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Karl Swärd

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Awahan Rahman; Yulia Shakirova; Kristina E Andersson; Patrik Brundin; Mari Ekman; Jonas S Erjefält; Jia-Yi Li; Matthias Mörgelin; Karl Swärd
Late onset vascular dysfunction in the R6/1 model of Huntington's disease.
Mardjaneh Sadegh Karbalaei; Alva Mansten; Catarina Rippe; Sebastian Albinsson; Mari Ekman; Bengt Uvelius; Karl Swärd
Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice.
Karolina M Turczynska; Per Hellstrand; Mardjaneh Karbalaei Sadegh; Karl Swärd; Sebastian Albinsson
MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channels.

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All Publications

2013: Awahan Rahman; Yulia Shakirova; Kristina E Andersson; Patrik Brundin; Mari Ekman; Jonas S Erjefält; Jia-Yi Li; Matthias Mörgelin; Karl Swärd
Late onset vascular dysfunction in the R6/1 model of Huntington's disease.
European journal of pharmacology 2013;698(1-3):345-53.
2012: Mardjaneh Sadegh Karbalaei; Alva Mansten; Catarina Rippe; Sebastian Albinsson; Mari Ekman; Bengt Uvelius; Karl Swärd
Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice.
European journal of pharmacology 2012;689(1-3):179-85.
2012: Karolina M Turczynska; Per Hellstrand; Mardjaneh Karbalaei Sadegh; Karl Swärd; Sebastian Albinsson
MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channels.
The Journal of biological chemistry 2012;287(23):19199-206.
2012: Mari Ekman; Matthias Mörgelin; Catarina Rippe; Mardjaneh Karbalaei Sadegh; Saeed Dabestani; Bengt Uvelius; Karl Swärd
Association of muscarinic M₃ receptors and Kir6.1 with caveolae in human detrusor muscle.
European journal of pharmacology 2012;683(1-3):238-45.
2012: Mardjaneh Karbalaei Sadegh; Karl Swärd; Bengt Uvelius; Mari Ekman; Catarina Rippe; Sebastian Albinsson
Deletion of Dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmission.
PloS one 2012;7(4):e35882.
2011: Mardjaneh Karbalaei Sadegh; Mari Ekman; Catarina Rippe; Frank Sundler; Nils Wierup; Michiko Mori; Bengt Uvelius; Karl Swärd
Biomechanical properties and innervation of the female caveolin-1-deficient detrusor.
British journal of pharmacology 2011;162(5):1156-70.
2010: Yulia Shakirova; Karl Swärd; Bengt Uvelius; Mari Ekman
Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder.
European journal of pharmacology 2010;649(1-3):362-8.
2010: Karl Swärd; Bengt Uvelius
[Caveolae-invaginations in the cell membrane with complex function. Defects in caveolae gene connected to severe congenital diseases].
Läkartidningen 2010;107(26-28):1705-8.
2010: Yulia Shakirova; Michiko Mori; Mari Ekman; Jonas Erjefält; Bengt Uvelius; Karl Swärd
Human urinary bladder smooth muscle is dependent on membrane cholesterol for cholinergic activation.
European journal of pharmacology 2010;634(1-3):142-8.
2010: Kristina E Andersson; Tina Immerstrand; Karl Swärd; Björn Bergenståhl; Marie W Lindholm; Rickard Oste; Per Hellstrand
Effects of oats on plasma cholesterol and lipoproteins in C57BL/6 mice are substrain specific.
The British journal of nutrition 2010;103(4):513-21.
2009: Gustaf Grände; Catarina Rippe; Anna Rippe; Awahan Rahman; Karl Swärd; Bengt Rippe
Unaltered size selectivity of the glomerular filtration barrier in caveolin-1 knockout mice.
American journal of physiology. Renal physiology 2009;297(2):F257-62.
2009: Ulrika E A Mårtensson; S Albert Salehi; Sara Windahl; Maria F Gomez; Karl Swärd; Joanna Daszkiewicz-Nilsson; Anna Wendt; Niklas Andersson; Per Hellstrand; Per-Olof Grände; Christer Owman; Clifford J Rosen; Martin Adamo; Ingmar Lundquist; Patrik Rorsman; Bengt-Olof Nilsson; Claes Ohlsson; Björn Olde; L M Fredrik Leeb-Lundberg
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.
Endocrinology 2009;150(2):687-98.
2009: A Rahman; Karl Swärd
The role of caveolin-1 in cardiovascular regulation.
Acta physiologica (Oxford, England) 2009;195(2):231-45.
2009: Yulia Shakirova; Petter Hedlund; Karl Swärd
Impaired nerve-mediated relaxation of penile tissue from caveolin-1 deficient mice.
European journal of pharmacology 2009;602(2-3):399-405.
2008: Pedro J Gomez-Pinilla; Maria F Gomez; Karl Swärd; Petter Hedlund; Per Hellstrand; Pedro J Camello; Karl-Erik Andersson; María J Pozo
Melatonin restores impaired contractility in aged guinea pig urinary bladder.
Journal of pineal research 2008;44(4):416-25.
2008: Sebastian Albinsson; Ina Nordström; Karl Swärd; Per Hellstrand
Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.
American journal of physiology. Cell physiology 2008;294(1):C271-9.
2007: Sebastian Albinsson; Yulia Shakirova; Anna Rippe; Maria Baumgarten; Bert-Inge Rosengren; Catarina Rippe; Rupert Hallmann; Per Hellstrand; Bengt Rippe; Karl Swärd
Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(3):R1222-31.
2007: Pedro J Gomez-Pinilla; Maria F Gomez; Petter Hedlund; Karl Swärd; Per Hellstrand; Pedro J Camello; María J Pozo; Karl-Erik Andersson
Effect of melatonin on age associated changes in Guinea pig bladder function.
The Journal of urology 2007;177(4):1558-61.
2007: Anna Rippe; Catarina Rippe; Karl Swärd; Bengt Rippe
Disproportionally low clearance of macromolecules from the plasma to the peritoneal cavity in a mouse model of peritoneal dialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(1):88-95.
2006: Yulia Shakirova; Johan Bonnevier; Sebastian Albinsson; Mikael Adner; Bengt Rippe; Jonas Broman; Anders Arner; Karl Swärd
Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1.
American journal of physiology. Cell physiology 2006;291(6):C1326-35.
2006: Rebecka Nilsson; Faiyaz Ahmad; Karl Swärd; Ulrika Andersson; marie weston; Vincent C Manganiello; Eva Degerman
Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes.
Cellular signalling 2006;18(10):1713-21.
2006: Bert-Inge Rosengren; Anna Rippe; Catarina Rippe; Daniele Venturoli; Karl Swärd; Bengt Rippe
Transvascular protein transport in mice lacking endothelial caveolae.
American journal of physiology. Heart and circulatory physiology 2006;291(3):H1371-7.
2005: Max Levin; Seth Goldbarg; Anders Lindqvist; Karl Swärd; Christine Roman; Bao Mei Liu; Lillemor Mattsson Hultén; Jan Borén; Ronald I Clyman
ATP depletion and cell death in the neonatal lamb ductus arteriosus.
Pediatric research 2005;57(6):801-5.
2004: Andreas Bergdahl; Karl Swärd
Caveolae-associated signalling in smooth muscle.
Canadian journal of physiology and pharmacology 2004;82(5):289-99.
2004: Ulf Malmqvist; Petter Hedlund; Karl Swärd; Karl-Erik Andersson
Female pig urethral tone is dependent on Rho guanosine triphosphatases and Rho-associated kinase.
The Journal of urology 2004;171(5):1955-8.
2004: Asad Zeidan; Karl Swärd; Ina Nordström; Eva Ekblad; Janet C L Zhang; Michael S Parmacek; Per Hellstrand
Ablation of SM22alpha decreases contractility and actin contents of mouse vascular smooth muscle.
FEBS letters 2004;562(1-3):141-6.
2003: Andreas Bergdahl; Maria F Gomez; Karl Dreja; Shang-Zhong Xu; Mikael Adner; David J Beech; Jonas Broman; Per Hellstrand; Karl Swärd
Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.
Circulation research 2003;93(9):839-47.
2003: Andreas Bergdahl; Erik Persson; Per Hellstrand; Karl Swärd
Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery.
Pharmacology & toxicology 2003;93(3):128-34.
2003: Asad Zeidan; Jonas Broman; Per Hellstrand; Karl Swärd
Cholesterol dependence of vascular ERK1/2 activation and growth in response to stretch: role of endothelin-1.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1528-34.
2003: Asad Zeidan; Ina Nordström; Sebastian Albinsson; Ulf Malmqvist; Karl Swärd; Per Hellstrand
Stretch-induced contractile differentiation of vascular smooth muscle: sensitivity to actin polymerization inhibitors.
American journal of physiology. Cell physiology 2003;284(6):C1387-96.
2003: Karl Swärd; Mitsuo Mita; David P Wilson; Jing Ti Deng; Marija Susnjar; Michael P Walsh
The role of RhoA and Rho-associated kinase in vascular smooth muscle contraction.
Current hypertension reports 2003;5(1):66-72.
2002: Mikael Adner; Andrew C Rose; Yaping Zhang; Karl Swärd; Mikael Benson; Rolf Uddman; Nigel P Shankley; Lars-Olaf Cardell
An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.
British journal of pharmacology 2002;137(7):971-82.
2002: Bengt-Olof Nilsson; Maria F Gomez; Karl Swärd; Per Hellstrand
Regulation of Ca2+ channel and phosphatase activities by polyamines in intestinal and vascular smooth muscle--implications for cellular growth and contractility.
Acta physiologica Scandinavica 2002;176(1):33-41.
2002: Karl Dreja; Marianne Voldstedlund; Jørgen Vinten; Jørgen Tranum-Jensen; Per Hellstrand; Karl Swärd
Cholesterol depletion disrupts caveolae and differentially impairs agonist-induced arterial contraction.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1267-72.
2002: Anders Lindqvist; Karl Dreja; Karl Swärd; Per Hellstrand
Effects of oxygen tension on energetics of cultured vascular smooth muscle.
American journal of physiology. Heart and circulatory physiology 2002;283(1):H110-7.
2002: Karl Swärd; Karl Dreja; Anders Lindqvist; Erik Persson; Per Hellstrand
Influence of mitochondrial inhibition on global and local [Ca(2+)](I) in rat tail artery.
Circulation research 2002;90(7):792-9.
2000: L P Weber; M Seto; Y Sasaki; Karl Swärd; Michael P Walsh
The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle.
The Biochemical journal 2000;352 Pt 2():573-82.
2000: Karl Swärd; Karl Dreja; Marija Susnjar; Per Hellstrand; D J Hartshorne; Michael P Walsh
Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum.
The Journal of physiology 2000;522 Pt 1():33-49.
1998: Karl Swärd; Karl Dreja; Per Hellstrand
Contractile effects of polycations in permeabilized smooth muscle.
Journal of muscle research and cell motility 1998;19(5):463-72.
1998: Bengt-Olof Nilsson; A Lindqvist; R K Pandita; Karl Swärd; K Persson
Effects of polyamine synthesis inhibition on polyamines, growth and mechanical properties in hypertrophic rat urinary bladder.
Pharmacology & toxicology 1998;82(6):287-94.
1997: M Gomez; Karl Swärd
Long-term regulation of contractility and calcium current in smooth muscle.
The American journal of physiology 1997;273(5 Pt 1):C1714-20.
1997: Karl Swärd; Bengt-Olof Nilsson; Per Hellstrand
Inhibition of polyamine synthesis influences contractility of intestinal smooth muscle in culture.
The American journal of physiology 1997;273(1 Pt 1):C77-84.
1995: Karl Swärd; M D Pato; Bengt-Olof Nilsson; I Nordström; Per Hellstrand
Polyamines inhibit myosin phosphatase and increase LC20 phosphorylation and force in smooth muscle.
The American journal of physiology 1995;269(3 Pt 1):C563-71.
1994: Karl Swärd; Bengt-Olof Nilsson; Per Hellstrand
Polyamines increase Ca2+ sensitivity in permeabilized smooth muscle of guinea pig ileum.
The American journal of physiology 1994;266(6 Pt 1):C1754-63.
1994: M L Lydrup; Karl Swärd; Per Hellstrand
Effect of glibenclamide on membrane response to metabolic inhibition in smooth muscle of rat portal vein.
Journal of vascular research 1994;31(2):82-91.
1993: Karl Swärd; M Josefsson; M L Lydrup; Per Hellstrand
Effects of metabolic inhibition on cytoplasmic calcium and contraction in smooth muscle of rat portal vein.
Acta physiologica Scandinavica 1993;148(3):265-72.