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Leonardo A. Meza-Zepeda

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Gene Dosage

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Oligonucleotide Array Sequence Analysis

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Nucleic Acid Hybridization

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Hege O Ohnstad; Jinchang Sun; Lyubomir T Vassilev; Bodil Bjerkehagen; Russell Castro; Karen-Marie Heintz; Stine H Kresse; Leonardo A. Meza-Zepeda; Ola Myklebost
Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma.
Su Qu; Leonardo A. Meza-Zepeda; Solveig Mjelstad Olafsrud; Fahri Saatcioglu
Rapid Gene Expression Changes in Peripheral Blood Lymphocytes upon Practice of a Comprehensive Yoga Program.
Sarah R Herlofsen; Torill Høiby; Robbyn Issner; Leonardo A. Meza-Zepeda; Tarjei S Mikkelsen; Li Wang; Xiaolan Zhang; Jan Christian Bryne; Philippe Collas; Michael J Coyne; Hongcang Gu; Patrick Boyle; Jan E Brinchmann
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.

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All Publications

2013: Hege O Ohnstad; Jinchang Sun; Lyubomir T Vassilev; Bodil Bjerkehagen; Russell Castro; Karen-Marie Heintz; Stine H Kresse; Leonardo A. Meza-Zepeda; Ola Myklebost
Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma.
Cancer 2013;119(5):1013-22.
2013: Su Qu; Leonardo A. Meza-Zepeda; Solveig Mjelstad Olafsrud; Fahri Saatcioglu
Rapid Gene Expression Changes in Peripheral Blood Lymphocytes upon Practice of a Comprehensive Yoga Program.
PloS one 2013;8(4):e61910.
2013: Sarah R Herlofsen; Torill Høiby; Robbyn Issner; Leonardo A. Meza-Zepeda; Tarjei S Mikkelsen; Li Wang; Xiaolan Zhang; Jan Christian Bryne; Philippe Collas; Michael J Coyne; Hongcang Gu; Patrick Boyle; Jan E Brinchmann
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.
BMC genomics 2013;14():105.
2012: Rolf I Skotheim; Eivind Hovig; Per E Lønning; Ragnhild A Lothe; Leonardo A. Meza-Zepeda; Ola Myklebost
[Genome sequencing for personalized cancer treatment].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2012;132(21):2406-8.
2012: Dag Henrik Reikvam; Anders Sandvik; Hauke Smidt; Leonardo A. Meza-Zepeda; Muriel Derrien; Alexander Erofeev; Peter Gaustad; Vedrana Grcic; Rejoanoul Islam; Frode L Jahnsen; Finn-Eirik Johansen
Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice.
European journal of immunology 2012;42(11):2959-70.
2012: Marieke L Kuijjer; Ana B Lid; Leonardo A. Meza-Zepeda; Ola Myklebost; Helene Roelofs; Halfdan Rydbeck; Emilie P Buddingh; Horst Bürger; Pancras C W Hogendoorn; Stine H Kresse; Anne-Marie Cleton-Jansen
Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data.
Genes, chromosomes & cancer 2012;51(7):696-706.
2012: Pierre Chymkowitch; Vegard Eldholm; Magnar Bjørås; Jessica M Lindvall; Susanne Lorenz; Leonardo A. Meza-Zepeda; Christine Zimmermann; Jorrit M Enserink
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(26):10450-5.
2012: Magne Skårn; Meng-Yu Wang; Leonardo A. Meza-Zepeda; Heidi Maria Namløs; Paul Noordhuis; Ola Myklebost
Adipocyte differentiation of human bone marrow-derived stromal cells is modulated by microRNA-155, microRNA-221, and microRNA-222.
Stem cells and development 2012;21(6):873-83.
2012: Linn G Bjørnstad; Trine J Meza; Leonardo A. Meza-Zepeda; Solveig M Olafsrud; Marit Otterlei; Pål Ø Falnes
Human ALKBH4 interacts with proteins associated with transcription.
PloS one 2012;7(11):e49045.
2012: Stine H Kresse; Knut Liestøl; Ana H Barragan-Polania; Anne-Marie Cleton-Jansen; Pancras C W Hogendoorn; Eivind Hovig; Ola Myklebost; Heidi Maria Namløs; Halfdan Rydbeck; Massimo Serra; Magne Skårn; Leonardo A. Meza-Zepeda
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PloS one 2012;7(11):e48262.
2012: Heidi Maria Namløs; Massimo Serra; Ingrid H G Østensen; Tale Barøy; Horst Bürger; Anne-Marie Cleton-Jansen; Stine H Kresse; Marieke L Kuijjer; Leonardo A. Meza-Zepeda; Ola Myklebost
Modulation of the osteosarcoma expression phenotype by microRNAs.
PloS one 2012;7(10):e48086.
2011: Hanne-Sofie S Dahlback; Håvard E Danielsen; Radek Fric; Bård K Krossnes; Torstein R Meling; Leonardo A. Meza-Zepeda; Petter Brandal; Sverre Heim
Multiple chromosomal monosomies are characteristic of giant cell ependymoma.
Human pathology 2011;42(12):2042-6.
2011: Geir Olav Hjortland; Hanne Hoifodt; Knut H Hole; Leonardo A. Meza-Zepeda; Ola Myklebost; Anne Hansen Ree; Sigbjørn Smeland; Siri Tveito; Klaus Beiske; Per J Bohler; Oystein Fodstad; Eivind Hovig
Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma.
BMC cancer 2011;11():455.
2011: Marieke L Kuijjer; Antonio Llombart Bosch; Isidro Machado; Leonardo A. Meza-Zepeda; Ola Myklebost; Heidi M Namløs; Massimo Serra; Esther I Hauben; Pancras C W Hogendoorn; Stine H Kresse; Anne-Marie Cleton-Jansen
mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts.
BMC medical genomics 2011;4():66.
2011: Dag Henrik Reikvam; Alexander Erofeev; Anders Sandvik; Vedrana Grcic; Frode L Jahnsen; Peter Gaustad; Kathy D McCoy; Andrew J Macpherson; Leonardo A. Meza-Zepeda; Finn-Eirik Johansen
Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression.
PloS one 2011;6(3):e17996.
2010: Marianne Brodtkorb Eide; Knut Liestøl; Ole Christian Lingjaerde; Marit E Hystad; Stine H Kresse; Leonardo A. Meza-Zepeda; Ola Myklebost; Gunhild Trøen; Hege Vangstein Aamot; Harald Holte; Erlend Smeland; Jan Delabie
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones.
Blood 2010;116(9):1489-97.
2010: Stine H Kresse; Hege O Ohnstad; Bodil Bjerkehagen; Ola Myklebost; Leonardo A. Meza-Zepeda
DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation.
PloS one 2010;5(11):e15378.
2010: Stine H Kresse; Karoly Szuhai; Ana H Barragan-Polania; Halfdan Rydbeck; Anne-Marie Cleton-Jansen; Ola Myklebost; Leonardo A. Meza-Zepeda
Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours.
BMC research notes 2010;3():223.
2010: Jørn Henriksen; Marianne Stabell; Leonardo A. Meza-Zepeda; Silje Au Lauvrak; Moustapha Kassem; Ola Myklebost
Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells.
BMC cancer 2010;10():329.
2010: Laura Ottaviano; Karl-Ludwig Schaefer; Melanie Gajewski; Wolfgang Huckenbeck; Stefan Baldus; Uwe Rogel; Carlos Mackintosh; Enrique de Alava; Ola Myklebost; Stine H Kresse; Leonardo A. Meza-Zepeda; Massimo Serra; Anne-Marie Cleton-Jansen; Pancras C W Hogendoorn; Horst Buerger; Thomas Aigner; Helmut E Gabbert; Christopher Poremba
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes, chromosomes & cancer 2010;49(1):40-51.
2009: Thea Kristin Våtsveen; Erming Tian; Stine H Kresse; Leonardo A. Meza-Zepeda; Ana Gabrea; Oleg Glebov; Hong Yan Dai; Anders Sundan; W Michael Kuehl; Magne Børset
OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus.
Leukemia research 2009;33(12):1670-7.
2009: Gustav Lehne; Unn-Hilde Grasmo-Wendler; Jeanne-Marie Berner; Leonardo A. Meza-Zepeda; Birgitte Lid Adamsen; Aksel Flack; Andrew Reiner; Ole Petter Fraas Clausen; Eivind Hovig; Ola Myklebost
Upregulation of stem cell genes in multidrug resistant K562 leukemia cells.
Leukemia research 2009;33(10):1379-85.
2009: Stine H Kresse; Hege O Ohnstad; Erik B Paulsen; Bodil Bjerkehagen; Karoly Szuhai; Massimo Serra; Karl-Ludwig Schaefer; Ola Myklebost; Leonardo A. Meza-Zepeda
LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization.
Genes, chromosomes & cancer 2009;48(8):679-93.
2008: Helle Lybaek; Leonardo A. Meza-Zepeda; Stine H Kresse; Trude Høysaeter; Vidar M Steen; Gunnar Houge
Array-CGH fine mapping of minor and cryptic HR-CGH detected genomic imbalances in 80 out of 590 patients with abnormal development.
European journal of human genetics : EJHG 2008;16(11):1318-28.
2008: Eric Roman; Leonardo A. Meza-Zepeda; Stine H Kresse; Ola Myklebost; Endre N Vasstrand; Salah O Ibrahim
Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization.
Oncology reports 2008;20(4):825-43.
2008: Elisabeth Larsen; Liv Kleppa; Trine J Meza; Leonardo A. Meza-Zepeda; Christina Rada; Cesilie G Castellanos; Guro F Lien; Gaute J Nesse; Michael S Neuberger; Jon K Laerdahl; Richard William Doughty; Arne Klungland
Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants.
Cancer research 2008;68(12):4571-9.
2008: Leonardo A. Meza-Zepeda; Agate Noer; John Arne Dahl; Francesca Micci; Ola Myklebost; Philippe Collas
High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence.
Journal of cellular and molecular medicine 2008;12(2):553-63.
2008: Stine H Kresse; Magne Skårn; Hege O Ohnstad; Heidi M Namløs; Bodil Bjerkehagen; Ola Myklebost; Leonardo A. Meza-Zepeda
DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH.
Molecular cancer 2008;7():48.
2008: Heidi Lyng; Malin Lando; Runar S Brøvig; Debbie H Svendsrud; Morten Johansen; Eivind Galteland; Odd T Brustugun; Leonardo A. Meza-Zepeda; Ola Myklebost; Gunnar Kristensen; Eivind Hovig; Trond Stokke
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data.
Genome biology 2008;9(5):R86.
2007: Michael Zangani; Marianne Frøyland; Gao Yue Qiu; Leonardo A. Meza-Zepeda; Jeffery L Kutok; Keith M Thompson; Ludvig A Munthe; Bjarne Bogen
Lymphomas can develop from B cells chronically helped by idiotype-specific T cells.
The Journal of experimental medicine 2007;204(5):1181-91.
2006: Leonardo A. Meza-Zepeda; Stine H Kresse; Ana H Barragan-Polania; Bodil Bjerkehagen; Hege O Ohnstad; Heidi Maria Namløs; Junbai Wang; Bjørn E Kristiansen; Ola Myklebost
Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas.
Cancer research 2006;66(18):8984-93.
2006: Anne Hansen Ree; Trond Stokke; Ase Bratland; Sebastian Patzke; Ragnhild V Nome; Sigurd Folkvord; Leonardo A. Meza-Zepeda; Kjersti Flatmark; Oystein Fodstad; Yvonne Andersson
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting.
Anticancer research 2006;26(3A):1909-16.
2006: Einar A Sivertsen; Eivind Galteland; D Mu; Harald Holte; Leonardo A. Meza-Zepeda; Ola Myklebost; Sebastian Patzke; Erlend Smeland; Trond Stokke
Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas.
Leukemia 2006;20(3):539-42.
2005: Eivind Galteland; Einar A Sivertsen; Debbie H Svendsrud; L Smedshammer; Stine H Kresse; Leonardo A. Meza-Zepeda; Ola Myklebost; Z Suo; D Mu; Paula M DeAngelis; Trond Stokke
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas.
Leukemia 2005;19(12):2313-23.
2005: Stine H Kresse; Jeanne-Marie Berner; Leonardo A. Meza-Zepeda; Simon G Gregory; Wen-Lin Kuo; Joe Gray; Anne Forus; Ola Myklebost
Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH.
Molecular cancer 2005;4():39.
2004: Junbai Wang; Leonardo A. Meza-Zepeda; Stine H Kresse; Ola Myklebost
M-CGH: analysing microarray-based CGH experiments.
BMC bioinformatics 2004;5():74.
2004: Malin Nilsson; Leonardo A. Meza-Zepeda; Fredrik Mertens; Anne Forus; Ola Myklebost; Nils Mandahl
Amplification of chromosome 1 sequences in lipomatous tumors and other sarcomas.
International journal of cancer. Journal international du cancer 2004;109(3):363-9.
2004: Mef Nilbert; Leonardo A. Meza-Zepeda; Princy Francis; Jeanne-Marie Berner; Heidi Maria Namløs; Josefin Fernebro; Ola Myklebost
Lessons from genetic profiling in soft tissue sarcomas.
Acta orthopaedica Scandinavica. Supplementum 2004;75(311):35-50.
2002: Trine J Meza; Biljana Stangeland; Inderjit S Mercy; Magne Skårn; Dag A Nymoen; Anita Berg; Melinka A Butenko; Anne-Mari Håkelien; Camilla Haslekås; Leonardo A. Meza-Zepeda; Reidunn Aalen
Analyses of single-copy Arabidopsis T-DNA-transformed lines show that the presence of vector backbone sequences, short inverted repeats and DNA methylation is not sufficient or necessary for the induction of transgene silencing.
Nucleic acids research 2002;30(20):4556-66.
2002: Leonardo A. Meza-Zepeda; Anne Forus; Birgitte Lygren; Anine B Dahlberg; Linda H Godager; Andrew P South; Ingo Marenholz; Maria Lioumi; Vivi Ann Flørenes; Gunhild M Maelandsmo; Massimo Serra; Dietmar Mischke; Dean Nizetic; Jiannis Ragoussis; Maija Tarkkanen; Jahn M Nesland; Sakari Knuutila; Ola Myklebost
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21.
Oncogene 2002;21(14):2261-9.
2001: Anne Forus; Bodil Bjerkehagen; Nicolas Sirvent; Leonardo A. Meza-Zepeda; Jean-Michel Coindre; Jeanne-Marie Berner; Ola Myklebost; Florence Pedeutour
A well-differentiated liposarcoma with a new type of chromosome 12-derived markers.
Cancer genetics and cytogenetics 2001;131(1):13-8.
2001: Anne Forus; Anna D'Angelo; Jørn Henriksen; Giuseppe Merla; Gunhild M Maelandsmo; Vivi Ann Flørenes; Stefano Olivieri; Bodil Bjerkehagen; Leonardo A. Meza-Zepeda; F del Vecchio Blanco; C Müller; Francesca Sanvito; J Kononen; Jahn M Nesland; Øystein Fodstad; Alexandre Reymond; Olli Kallioniemi; Gianluigi Arrigoni; Andrea Ballabio; Ola Myklebost; Massimo Zollo
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Oncogene 2001;20(47):6881-90.
2001: Leonardo A. Meza-Zepeda; Jeanne-Marie Berner; Jørn Henriksen; Andrew P South; Florence Pedeutour; Anine B Dahlberg; Linda H Godager; Dean Nizetic; Anne Forus; Ola Myklebost
Ectopic sequences from truncated HMGIC in liposarcomas are derived from various amplified chromosomal regions.
Genes, chromosomes & cancer 2001;31(3):264-73.
2001: Anne Forus; Marcelo L Larramendy; Leonardo A. Meza-Zepeda; Bodil Bjerkehagen; Linda H Godager; Anine B Dahlberg; Gunnar Saeter; Sakari Knuutila; Ola Myklebost
Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma: amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases.
Cancer genetics and cytogenetics 2001;125(2):100-11.
1999: Anne Hansen Ree; M Tvermyr; Olav Engebraaten; M Rooman; Oystein Røsok; Eivind Hovig; Leonardo A. Meza-Zepeda; Oyvind S Bruland; Oystein Fodstad
Expression of a novel factor in human breast cancer cells with metastatic potential.
Cancer research 1999;59(18):4675-80.
1998: Anne Forus; Jeanne-Marie Berner; Leonardo A. Meza-Zepeda; Gunnar Saeter; Dietmar Mischke; Oystein Fodstad; Ola Myklebost
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas.
British journal of cancer 1998;78(4):495-503.
1997: Jeanne-Marie Berner; Leonardo A. Meza-Zepeda; P F Kools; Anne Forus; E F Schoenmakers; W J Van de Ven; Oystein Fodstad; Ola Myklebost
HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas.
Oncogene 1997;14(24):2935-41.
1996: M M Baudo; Leonardo A. Meza-Zepeda; E Tapio Palva; P Heino
Induction of homologous low temperature and ABA-responsive genes in frost resistant (Solanum commersonii) and frost-sensitive (Solanum tuberosum cv. Bintje) potato species.
Plant molecular biology 1996;30(2):331-6.