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Pandelakis Koni

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Pandelakis Koni; Jeffrey R Lee; Andrew L Mellor; Stephen L Nutt; Yutetsu Ametani; Anna Bolduc; Richard A Flavell; Lei Huang; Masahito Kamanaka; Mayuko Takezaki; Takeshi Tsubata; Michiko Shimoda
Constitutively CD40-activated B cells regulate CD8 T cell inflammatory response by IL-10 induction.
Madhav D Sharma; Deyan Hou; Babak Baban; Pandelakis Koni; Yukai He; Phillip R Chandler; Bruce R Blazar; Andrew L Mellor; David H Munn
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.
Anna Bolduc; Eugene Long; Dale Stapler; Marilia I Cascalho; Takeshi Tsubata; Pandelakis Koni; Michiko Shimoda
Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas.

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All Publications

2013: Pandelakis Koni; Jeffrey R Lee; Andrew L Mellor; Stephen L Nutt; Yutetsu Ametani; Anna Bolduc; Richard A Flavell; Lei Huang; Masahito Kamanaka; Mayuko Takezaki; Takeshi Tsubata; Michiko Shimoda
Constitutively CD40-activated B cells regulate CD8 T cell inflammatory response by IL-10 induction.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3189-96.
2010: Madhav D Sharma; Deyan Hou; Babak Baban; Pandelakis Koni; Yukai He; Phillip R Chandler; Bruce R Blazar; Andrew L Mellor; David H Munn
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.
Immunity 2010;33(6):942-54.
2010: Anna Bolduc; Eugene Long; Dale Stapler; Marilia I Cascalho; Takeshi Tsubata; Pandelakis Koni; Michiko Shimoda
Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):220-30.
2010: Burles A Johnson; David J Kahler; Babak Baban; Phillip R Chandler; Baolin Kang; Michiko Shimoda; Pandelakis Koni; Jeanene Pihkala; Bojan Vilagos; Meinrad Busslinger; David H Munn; Andrew L Mellor
B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(23):10644-8.
2009: Botond Z Igyarto; Matthew C Jenison; Jan C Dudda; Axel Roers; Werner Müller; Pandelakis Koni; Daniel J Campbell; Mark J Shlomchik; Daniel H Kaplan
Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5085-93.
2009: Babak Baban; Phillip R Chandler; Madhav D Sharma; Jeanene P S Pihkala; Pandelakis Koni; David H Munn; Andrew L Mellor
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2475-83.
2009: Yoshitsugu Takabatake; Tatsuki Sugiyama; Hiroshi Kohara; Taiji Matsusaka; Hidetake Kurihara; Pandelakis Koni; Yasuyuki Nagasawa; Takayuki Hamano; Isao Matsui; Noritaka Kawada; Enyu Imai; Takashi Nagasawa; Hiromi Rakugi; Yoshitaka Isaka
The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.
Journal of the American Society of Nephrology : JASN 2009;20(8):1714-23.
2009: Madhav D Sharma; Deyan Hou; Yanjun Liu; Pandelakis Koni; Richard Metz; Phillip R Chandler; Andrew L Mellor; Yukai He; David H Munn
Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.
Blood 2009;113(24):6102-11.
2008: Adrian Liston; Katherine M Nutsch; Andrew G Farr; Jennifer M Lund; Jeffery P Rasmussen; Pandelakis Koni; Alexander Y Rudensky
Differentiation of regulatory Foxp3+ T cells in the thymic cortex.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11903-8.
2008: Gabriela Pacholczyk; Rupali Suhag; Magdalena Mazurek; Suzanne M Dederscheck; Pandelakis Koni
Generation of C57BL/6 knockout mice using C3H x BALB/c blastocysts.
BioTechniques 2008;44(3):413-6.
2008: Rong Ou; Menghua Zhang; Lei Huang; Richard A Flavell; Pandelakis Koni; Dimitrios Moskofidis
Regulation of immune response and inflammatory reactions against viral infection by VCAM-1.
Journal of virology 2008;82(6):2952-65.
2007: Michiko Shimoda; Pandelakis Koni
MHC-restricted B-cell antigen presentation in memory B-cell maintenance and differentiation.
Critical reviews in immunology 2007;27(1):47-60.
2006: J Pablo Abonia; Jenny Hallgren; Tatiana Jones; Tong Shi; Yuhui Xu; Pandelakis Koni; Richard A Flavell; Joshua A Boyce; K Frank Austen; Tatiana G Jones
Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung.
Blood 2006;108(5):1588-94.
2006: Michiko Shimoda; Faith Mmanywa; Sunil K Joshi; Tao Li; Katsuya Miyake; Jeanene P S Pihkala; Jonathan A Abbas; Pandelakis Koni
Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6503-11.
2006: Michiko Shimoda; Tao Li; Jeanene P S Pihkala; Pandelakis Koni
Role of MHC class II on memory B cells in post-germinal center B cell homeostasis and memory response.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2122-33.
2005: Lois L Cavanagh; Roberto Bonasio; Irina B Mazo; Cornelia Halin; Guiying Cheng; Adrianus W M van der Velden; Annaiah Cariappa; Catharine Chase; Paul Russell; Michael N Starnbach; Pandelakis Koni; Shiv Pillai; Wolfgang Weninger; Ulrich H von Andrian
Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells.
Nature immunology 2005;6(10):1029-37.
2005: Koichi Hamada; Takehiko Sasaki; Pandelakis Koni; Miyuki Natsui; Hiroyuki Kishimoto; Junko Sasaki; Nobuyuki Yajima; Yasuo Horie; Go Hasegawa; Makoto Naito; Jun-Ichi Miyazaki; Toshio Suda; Hiroshi Itoh; Kazuwa Nakao; Tak Wah Mak; Toru Nakano; Akira Suzuki
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.
Genes & development 2005;19(17):2054-65.
2005: Tatiana Ulyanova; Linda Maree SCOTT; Gregory V Priestley; Yi Jiang; Betty Nakamoto; Pandelakis Koni; Thalia Papayannopoulou
VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin.
Blood 2005;106(1):86-94.
2005: Tang-Long Shen; Ann Y-J Park; Ana Alcaraz; Xu Peng; Ihnkyung Jang; Pandelakis Koni; Richard A Flavell; Hua Gu; Jun-Lin Guan
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis.
The Journal of cell biology 2005;169(6):941-52.
2005: J Pablo Abonia; K Frank Austen; Barrett J Rollins; Sunil K Joshi; Richard A Flavell; William Kuziel; Pandelakis Koni; Michael F Gurish
Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2.
Blood 2005;105(11):4308-13.
2005: Toshiaki Ara; Koji Tokoyoda; Rika Okamoto; Pandelakis Koni; Takashi Nagasawa
The role of CXCL12 in the organ-specific process of artery formation.
Blood 2005;105(8):3155-61.
2005: Irina B Mazo; Marek Honczarenko; Harry Leung; Lois L Cavanagh; Roberto Bonasio; Wolfgang Weninger; Katharina Engelke; Lijun Xia; Rodger P McEver; Pandelakis Koni; Leslie E Silberstein; Ulrich H von Andrian
Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells.
Immunity 2005;22(2):259-70.
2004: David H Munn; Madhav D Sharma; Deyan Hou; Babak Baban; Jeffrey R Lee; Scott J Antonia; Jane L Messina; Phillip R Chandler; Pandelakis Koni; Andrew L Mellor
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.
The Journal of clinical investigation 2004;114(2):280-90.
2004: Jianchao Xu; Peili Wang; Yanyan Li; Guoyong Li; Leonard K Kaczmarek; Yanling Wu; Pandelakis Koni; Richard A Flavell; Gary V Desir
The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3112-7.
2004: Debra A Fadool; K Tucker; R Perkins; G Fasciani; R N Thompson; Almetra D Parsons; J Michael Overton; Pandelakis Koni; R A Flavell; Leonard K Kaczmarek
Kv1.3 channel gene-targeted deletion produces "Super-Smeller Mice" with altered glomeruli, interacting scaffolding proteins, and biophysics.
Neuron 2004;41(3):389-404.
2003: Pandelakis Koni; Rajesh Khanna; Martin C Chang; Michael D Tang; Leonard K Kaczmarek; Lyanne C Schlichter; Richard A Flavella
Compensatory anion currents in Kv1.3 channel-deficient thymocytes.
The Journal of biological chemistry 2003;278(41):39443-51.
2003: Andrew L Mellor; Babak Baban; Phillip R Chandler; Brendan Marshall; Kanchan Jhaver; Anna Hansen; Pandelakis Koni; Makio Iwashima; David H Munn
Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1652-5.
2003: Akira Suzuki; Tsuneyasu Kaisho; Minako Ohishi; Manae Tsukio-Yamaguchi; Takeshi Tsubata; Pandelakis Koni; Takehiko Sasaki; Tak Wah Mak; Toru Nakano
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.
The Journal of experimental medicine 2003;197(5):657-67.
2003: Jianchao Xu; Pandelakis Koni; Peili Wang; Guoyong Li; Leonard Kaczmarek; Yanling Wu; Yanyan Li; Richard A Flavell; Gary V Desir
The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight.
Human molecular genetics 2003;12(5):551-9.
2003: Thomas Welte; Samuel Shao-Min Zhang; Tian Wang; Zhiyuan Zhang; David G T Hesslein; Zhinan Yin; Arihiro Kano; Yoshiki Iwamoto; En Li; Joseph E Craft; Alfred L M Bothwell; Erol Fikrig; Pandelakis Koni; Richard A Flavell; Xin-Yuan Fu
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1879-84.
2002: Sunil K Joshi; Kahoko Hashimoto; Pandelakis Koni
Induced DNA recombination by Cre recombinase protein transduction.
Genesis (New York, N.Y. : 2000) 2002;33(1):48-54.
2002: Michael B A Oldstone; Richard E Race; Diane Thomas; Hanna Lewicki; Dirk Homann; Sara Smelt; Andreas Holz; Pandelakis Koni; David Lo; Bruce Chesebro; Richard Flavell
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.
Journal of virology 2002;76(9):4357-63.
2002: Kahoko Hashimoto; Sunil K Joshi; Pandelakis Koni
A conditional null allele of the major histocompatibility IA-beta chain gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):152-3.
2001: Thomas W Spahn; Adriano Fontana; A M C Faria; Anthony J Slavin; Hans-Pietro Eugster; Xingmin Zhang; Pandelakis Koni; Nancy H Ruddle; R A Flavell; Paul D Rennert; Howard L Weiner
Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches.
European journal of immunology 2001;31(4):1278-87.
2001: Pandelakis Koni; Sunil K Joshi; U A Temann; D Olson; L Burkly; Richard A Flavell
Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow.
The Journal of experimental medicine 2001;193(6):741-54.
2000: Laura Manuelidis; I Zaitsev; Pandelakis Koni; Zhi Yun Lu; Richard A Flavell; W Fritch
Follicular dendritic cells and dissemination of Creutzfeldt-Jakob disease.
Journal of virology 2000;74(18):8614-22.
1999: DP Berger; Denise Naniche; M T Crowley; Pandelakis Koni; Richard A Flavell; Michael B A Oldstone
Lymphotoxin-beta-deficient mice show defective antiviral immunity.
Virology 1999;260(1):136-47.
1999: Pandelakis Koni; Richard A Flavell
Lymph node germinal centers form in the absence of follicular dendritic cell networks.
The Journal of experimental medicine 1999;189(5):855-64.
1998: Pandelakis Koni; Richard A Flavell
A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymphotoxin beta.
The Journal of experimental medicine 1998;187(12):1977-83.
1997: Pandelakis Koni; R Sacca; P Lawton; Jeffrey L Browning; Nancy H Ruddle; Richard A Flavell
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice.
Immunity 1997;6(4):491-500.
1997: T Nakamura; Richard Lee; S Y Nam; Basel K al-Ramadi; Pandelakis Koni; Kim Bottomly; Eckhard R Podack; Richard A Flavell
Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2090-8.
1996: J Li; Pandelakis Koni; David Ellar
Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation.
Journal of molecular biology 1996;257(1):129-52.
1995: J Li; Pandelakis Koni; David Ellar
Crystallization of a membrane pore-forming protein with mosquitocidal activity from Bacillus thuringiensis subspecies kyushuensis.
Proteins 1995;23(2):290-3.
1995: Weiming XU; I G Charles; L Liu; Pandelakis Koni; S Moncada; P Emson
Molecular genetic analysis of the duplication of human inducible nitric oxide synthase (NOS2) sequences.
Biochemical and biophysical research communications 1995;212(2):466-72.
1994: Pandelakis Koni; David Ellar
Biochemical characterization of Bacillus thuringiensis cytolytic delta-endotoxins.
Microbiology (Reading, England) 1994;140 ( Pt 8)():1869-80.
1993: Pandelakis Koni; David Ellar
Cloning and characterization of a novel Bacillus thuringiensis cytolytic delta-endotoxin.
Journal of molecular biology 1993;229(2):319-27.