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Raj Puri

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Joseph Bekisz; Syed R Husain; Chase Johnson; Raj K Puri; Yuki Sato; Kathy Zoon
Immunomodulatory effects of interferons in malignancies.
Bhargavi Kondragunta; Antonio R Moreira; Raj K Puri; Kurt Brorson; Jing Han; Bharat H Joshi; Govind Rao
Bioreactor environment-sensitive sentinel genes as novel metrics for cell culture scale-down comparability.
Bhargavi Kondragunta; Antonio R Moreira; Raj K Puri; Kurt Brorson; Jing Han; Bharat H Joshi; Shaunak Uplekar; Govind Rao
Genomic analysis of a hybridoma batch cell culture metabolic status in a standard laboratory 5 L bioreactor.

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All Publications

2013: Joseph Bekisz; Syed R Husain; Chase Johnson; Raj K Puri; Yuki Sato; Kathy Zoon
Immunomodulatory effects of interferons in malignancies.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2013;33(4):154-61.
2012: Bhargavi Kondragunta; Antonio R Moreira; Raj K Puri; Kurt Brorson; Jing Han; Bharat H Joshi; Govind Rao
Bioreactor environment-sensitive sentinel genes as novel metrics for cell culture scale-down comparability.
Biotechnology progress 2012;28(5):1138-51.
2012: Bhargavi Kondragunta; Antonio R Moreira; Raj K Puri; Kurt Brorson; Jing Han; Bharat H Joshi; Shaunak Uplekar; Govind Rao
Genomic analysis of a hybridoma batch cell culture metabolic status in a standard laboratory 5 L bioreactor.
Biotechnology progress 2012;28(5):1126-37.
2012: Toshio Fujisawa; Bharat H Joshi; Raj K Puri
IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer.
International journal of cancer. Journal international du cancer 2012;131(2):344-56.
2012: Hideyuki Nakashima; Raj K Puri; Samuel Baron; Joseph Bekisz; Christopher R Clark; Joel Finbloom; Syed R Husain; Kotaro Miyake; Kathy Zoon
Potent antitumor effects of combination therapy with IFNs and monocytes in mouse models of established human ovarian and melanoma tumors.
Cancer immunology, immunotherapy : CII 2012;61(7):1081-92.
2012: Wu Ou; Raj K Puri; Akiko Suzuki; Evanthia Galanis; Syed R Husain; Bharat Joshi; Andrea Maisner; Michael P Marino; Jakob Reiser
Specific targeting of human interleukin (IL)-13 receptor α2-positive cells with lentiviral vectors displaying IL-13.
Human gene therapy methods 2012;23(2):137-47.
2012: Toshio Fujisawa; William A Gahl; Bharat H Joshi; Prabhudas S Patel; Benjamin Rubin; Akiko Suzuki; Raj K Puri
Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.
PloS one 2012;7(4):e34437.
2011: Hideyuki Nakashima; Jay A Berzofsky; Syed R Husain; Masaki Terabe; Raj K Puri
A novel combination immunotherapy for cancer by IL-13Rα2-targeted DNA vaccine and immunotoxin in murine tumor models.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):4935-46.
2011: Toshio Fujisawa; Hideyuki Nakashima; Atsushi Nakajima; Bharat H Joshi; Raj K Puri
Targeting IL-13Rα2 in human pancreatic ductal adenocarcinoma with combination therapy of IL-13-PE and gemcitabine.
International journal of cancer. Journal international du cancer 2011;128(5):1221-31.
2011: Toshio Fujisawa; Bharat H Joshi; Raj K Puri
Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer.
Journal of translational medicine 2011;9():37.
2010: Sandeep Kunwar; Susan Chang; Manfred Westphal; Michael A Vogelbaum; John Sampson; Gene Barnett; Mark Shaffrey; Zvi Ram; Joseph M Piepmeier; Michael Prados; David Croteau; Christoph Pedain; Pamela Leland; Syed R Husain; Bharat H Joshi; Raj K Puri
Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.
Neuro-oncology 2010;12(8):871-81.
2010: John H Sampson; Gary Archer; Christoph Pedain; Eva Wembacher-Schröder; Manfred Westphal; Sandeep Kunwar; Michael A Vogelbaum; April Coan; James E Herndon; Raghu Raghavan; Martin L Brady; David A Reardon; Allan H Friedman; Henry S Friedman; M Inmaculada Rodríguez-Ponce; Susan M Chang; Stephan Mittermeyer; David Croteau; Raj K Puri
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
Journal of neurosurgery 2010;113(2):301-9.
2010: Takeshi Shimamura; Toshio Fujisawa; Syed R Husain; Bharat Joshi; Raj K Puri
Interleukin 13 mediates signal transduction through interleukin 13 receptor alpha2 in pancreatic ductal adenocarcinoma: role of IL-13 Pseudomonas exotoxin in pancreatic cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(2):577-86.
2010: Hideyuki Nakashima; Toshio Fujisawa; Syed R Husain; Raj K Puri
Interleukin-13 receptor α2 DNA prime boost vaccine induces tumor immunity in murine tumor models.
Journal of translational medicine 2010;8():116.
2009: Toshio Fujisawa; Bharat Joshi; Atsushi Nakajima; Raj K Puri
A novel role of interleukin-13 receptor alpha2 in pancreatic cancer invasion and metastasis.
Cancer research 2009;69(22):8678-85.
2009: Bharat H Joshi; Raj K Puri
Tumor immunology.
Current molecular medicine 2009;9(6):665-6.
2009: Bhaskar Bhattacharya; Sachin Puri; Raj K Puri
A review of gene expression profiling of human embryonic stem cell lines and their differentiated progeny.
Current stem cell research & therapy 2009;4(2):98-106.
2009: Mitomu Kioi; Takeshi Shimamura; Hideyuki Nakashima; Makoto Hirota; Iwai Tohnai; Syed R Husain; Raj K Puri
IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2009;124(6):1440-8.
2009: Jing Han; Mitomu Kioi; Wei-Sing Chu; Jan L Kasperbauer; Scott E Strome; Raj K Puri
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma.
Head & neck oncology 2009;1():27.
2008: Bharat H Joshi; Pamela Leland; Alfonso Calvo; Jeffrey E Green; Raj K Puri
Human adrenomedullin up-regulates interleukin-13 receptor alpha2 chain in prostate cancer in vitro and in vivo: a novel approach to sensitize prostate cancer to anticancer therapy.
Cancer research 2008;68(22):9311-7.
2008: Takeshi Shimamura; Toshio Fujisawa; Syed R Husain; Mitomu Kioi; Atsushi Nakajima; Raj K Puri
Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4656-65.
2008: Hin C Lee; Mitomu Kioi; Jing Han; Raj K Puri; Jesse Goodman
Anaplasma phagocytophilum-induced gene expression in both human neutrophils and HL-60 cells.
Genomics 2008;92(3):144-51.
2008: Mitomu Kioi; Saraswathy Seetharam; Raj K Puri
Targeting IL-13Ralpha2-positive cancer with a novel recombinant immunotoxin composed of a single-chain antibody and mutated Pseudomonas exotoxin.
Molecular cancer therapeutics 2008;7(6):1579-87.
2008: Bharat H Joshi; Rada A Puri; Pamela Leland; Frederick Varricchio; Ghanshyam Gupta; Mehmet Kocak; Richard J Gilbertson; Raj K Puri
Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma.
Neuro-oncology 2008;10(3):265-74.
2007: Michael A Vogelbaum; John H Sampson; Sandeep Kunwar; Susan M Chang; Mark E Shaffrey; Anthony Asher; Frederick F Lang; David Croteau; Kristen Parker; Amy Y Grahn; Jeffrey W Sherman; S Rafat Husain; Raj K Puri
Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
Neurosurgery 2007;61(5):1031-7; discussion 1037-8.
2007: Takeshi Shimamura; Richard E Royal; Mitomu Kioi; Atsushi Nakajima; Syed R Husain; Raj K Puri
Interleukin-4 cytotoxin therapy synergizes with gemcitabine in a mouse model of pancreatic ductal adenocarcinoma.
Cancer research 2007;67(20):9903-12.
2007: Chu Chieh Hsia; Vladimir E Chizhikov; Amy X Yang; Angamuthu Selvapandiyan; Indira K Hewlett; Robert Duncan; Raj K Puri; Hira L Nakhasi; Gerardo G Kaplan
Microarray multiplex assay for the simultaneous detection and discrimination of hepatitis B, hepatitis C, and human immunodeficiency type-1 viruses in human blood samples.
Biochemical and biophysical research communications 2007;356(4):1017-23.
2007: Sandeep Kunwar; Michael D Prados; Susan M Chang; Mitchel S Berger; Frederick F Lang; Joseph M Piepmeier; John H Sampson; Zvi Ram; Philip H Gutin; Robert D Gibbons; Kenneth Aldape; David Croteau; Jeffrey W Sherman; Raj K Puri
Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(7):837-44.
2007: John H Sampson; Raghu Raghavan; James M Provenzale; David Croteau; David A Reardon; R Edward Coleman; Inmaculada Rodríguez Ponce; Ira Pastan; Raj K Puri; Christoph Pedain
Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin.
AJR. American journal of roentgenology 2007;188(3):703-9.
2007: John H Sampson; Martin L Brady; Neil Petry; David Croteau; Allan H Friedman; Henry S Friedman; Terence Wong; Darell D Bigner; Ira Pastan; Raj K Puri; Christoph Pedain
Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning.
Neurosurgery 2007;60(2 Suppl 1):ONS89-98; discussion ONS98-9.
2006: Amy X Yang; Josef Mejido; Bhaskar Bhattacharya; David Petersen; Jing Han; Ernest S Kawasaki; Raj K Puri
Analysis of the quality of contact-pin fabricated oligonucleotide microarrays.
Molecular biotechnology 2006;34(3):303-15.
2006: Mitomu Kioi; Saraswathy Seetharam; Raj K Puri
N-linked glycosylation of IL-13R alpha2 is essential for optimal IL-13 inhibitory activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(13):2378-80.
2006: Mitomu Kioi; Mariko Kawakami; Takeshi Shimamura; Syed R Husain; Raj K Puri
Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy.
Cancer 2006;107(6):1407-18.
2006: Koji Kawakami; Masaki Terabe; Mitomu Kioi; Jay A Berzofsky; Raj K Puri
Intratumoral therapy with IL13-PE38 results in effective CTL-mediated suppression of IL-13Ralpha2-expressing contralateral tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4678-86.
2006: Audrey Player; Yonghong Wang; Bhaskar Bhattacharya; Mahendra S Rao; Raj K Puri; Ernest S Kawasaki
Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines.
Stem cells and development 2006;15(3):315-23.
2006: Mitomu Kioi; Syed R Husain; David Croteau; Sandeep Kunwar; Raj K Puri
Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy.
Technology in cancer research & treatment 2006;5(3):239-50.
2006: Koji Kawakami; Masaki Terabe; Mariko Kawakami; Jay A Berzofsky; Raj K Puri
Characterization of a novel human tumor antigen interleukin-13 receptor alpha2 chain.
Cancer research 2006;66(8):4434-42.
2006: Jing Han; Richard L Farnsworth; Jawahar L Tiwari; Jie Tian; Hin Lee; Pranvera Ikonomi; Andrew P Byrnes; Jesse Goodman; Raj K Puri
Quality prediction of cell substrate using gene expression profiling.
Genomics 2006;87(4):552-9.
2006: Bharat H Joshi; Cory M Hogaboam; Pamela Dover; Syed R Husain; Raj K Puri
Role of interleukin-13 in cancer, pulmonary fibrosis, and other T(H)2-type diseases.
Vitamins and hormones 2006;74():479-504.
2006: Yongquan Luo; Bhaskar Bhattacharya; Amy X Yang; Raj K Puri; Mahendra S Rao
Designing, testing, and validating a microarray for stem cell characterization.
Methods in molecular biology (Clifton, N.J.) 2006;331():241-66.
2006: Sandeep Kunwar; Susan M Chang; Michael D Prados; Mitchel S Berger; John H Sampson; David Croteau; Jeffrey W Sherman; Amy Y Grahn; Vince S Shu; Jeanne L Dul; Syed R Husain; Bharat H Joshi; Christoph Pedain; Raj K Puri
Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies.
Neurosurgical focus 2006;20(4):E15.
2006: Takeshi Shimamura; Syed R Husain; Raj K Puri
The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy.
Neurosurgical focus 2006;20(4):E11.
2005: Mitomu Kioi; Satoru Takahashi; Mariko Kawakami; Koji Kawakami; Robert J Kreitman; Raj K Puri
Expression and targeting of interleukin-4 receptor for primary and advanced ovarian cancer therapy.
Cancer research 2005;65(18):8388-96.
2005: Koji Kawakami; Mariko Kawakami; Qi Liu; Raj K Puri
Combined effects of radiation and interleukin-13 receptor-targeted cytotoxin on glioblastoma cell lines.
International journal of radiation oncology, biology, physics 2005;63(1):230-7.
2005: Jing Han; Hin Lee; Nga Yen Nguyen; Serge L Beaucage; Raj K Puri
Novel multiple 5'-amino-modified primer for DNA microarrays.
Genomics 2005;86(2):252-8.
2005: Amy X Yang; Josef Mejido; Yongquan Luo; Xianmin Zeng; Catherine Schwartz; Tianxia Wu; Scott Thies; Bhaskar Bhattacharya; Jing Han; Bill Freed; Mahendra S Rao; Raj K Puri
Development of a focused microarray to assess human embryonic stem cell differentiation.
Stem cells and development 2005;14(3):270-84.
2005: Oscar Gonzalez-Moreno; Alfonso Calvo; Bharat H Joshi; Ibane Abasolo; Pamela Leland; Zhou Wang; Luis M Montuenga; Raj K Puri; Jeffrey E Green
Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin.
International journal of cancer. Journal international du cancer 2005;114(6):870-8.
2005: Koji Kawakami; Mitomu Kioi; Qi Liu; Mariko Kawakami; Raj K Puri
Evidence that IL-13R alpha2 chain in human glioma cells is responsible for the antitumor activity mediated by receptor-directed cytotoxin therapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(3):193-202.
2005: Mariko Kawakami; Koji Kawakami; Mitomu Kioi; Pamela Leland; Raj K Puri
Hodgkin lymphoma therapy with interleukin-4 receptor-directed cytotoxin in an infiltrating animal model.
Blood 2005;105(9):3707-13.
2005: Ian F Parney; Sandeep Kunwar; Michael McDermott; Mitchel Berger; Michael Prados; Soonmee Cha; David Croteau; Raj K Puri; Susan M Chang
Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma.
Journal of neurosurgery 2005;102(2):267-75.
2005: Bharat H Joshi; Raj K Puri
Optimization of expression and purification of two biologically active chimeric fusion proteins that consist of human interleukin-13 and Pseudomonas exotoxin in Escherichia coli.
Protein expression and purification 2005;39(2):189-98.
2005: Bhaskar Bhattacharya; Jingli Cai; Youngquan Luo; Takumi Miura; Josef Mejido; Sandii N Brimble; Xianmin Zeng; Thomas C Schulz; Mahendra S Rao; Raj K Puri
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies.
BMC developmental biology 2005;5():22.
2004: Koji Kawakami; Mariko Kawakami; Mitomu Kioi; Syed R Husain; Raj K Puri
Distribution kinetics of targeted cytotoxin in glioma by bolus or convection-enhanced delivery in a murine model.
Journal of neurosurgery 2004;101(6):1004-11.
2004: Mitomu Kioi; Koji Kawakami; Raj K Puri
Analysis of antitumor activity of an interleukin-13 (IL-13) receptor-targeted cytotoxin composed of IL-13 antagonist and Pseudomonas exotoxin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 1):6231-8.
2004: Mariko Kawakami; Koji Kawakami; Satoru Takahashi; Masato Abe; Raj K Puri
Analysis of interleukin-13 receptor alpha2 expression in human pediatric brain tumors.
Cancer 2004;101(5):1036-42.
2004: Koji Kawakami; Mariko Kawakami; Raj K Puri
Nitric oxide accelerates interleukin-13 cytotoxin-mediated regression in head and neck cancer animal model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5264-70.
2004: Bryce D Beseth; Robert B Cameron; Pamela Leland; Liang You; Frederick Varricchio; Robert J Kreitman; Richard A Maki; David M Jablons; Syed R Husain; Raj K Puri
Interleukin-4 receptor cytotoxin as therapy for human malignant pleural mesothelioma xenografts.
The Annals of thoracic surgery 2004;78(2):436-43; discussion 436-43.
2004: Claudia Jakubzick; Esther S Choi; Kristin J Carpenter; Steven Kunkel; Holly Evanoff; Fernando J Martinez; Kevin R Flaherty; Galen Toews; Thomas V Colby; William D Travis; Bharat H Joshi; Raj K Puri; Cory M Hogaboam
Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia.
The American journal of pathology 2004;164(6):1989-2001.
2004: Mitomu Kioi; Koji Kawakami; Raj K Puri
Mechanism of action of interleukin-13 antagonist (IL-13E13K) in cells expressing various types of IL-4R.
Cellular immunology 2004;229(1):41-51.
2004: Claudia Jakubzick; Esther S Choi; Steven Kunkel; Holly Evanoff; Fernando J Martinez; Raj K Puri; Kevin R Flaherty; Galen Toews; Thomas V Colby; Ella Annabelle Kazerooni; Barry H Gross; William D Travis; Cory M Hogaboam
Augmented pulmonary IL-4 and IL-13 receptor subunit expression in idiopathic interstitial pneumonia.
Journal of clinical pathology 2004;57(5):477-86.
2004: Bhaskar Bhattacharya; Takumi Miura; Ralph Brandenberger; Josef Mejido; Yongquan Luo; Amy X Yang; Bharat H Joshi; Irene Ginis; Scott Thies; Michal Amit; Ian Lyons; Brian G Condie; Joseph Itskovitz-Eldor; Mahendra S Rao; Raj K Puri
Gene expression in human embryonic stem cell lines: unique molecular signature.
Blood 2004;103(8):2956-64.
2004: Koji Kawakami; Mariko Kawakami; Raj K Puri
Specifically targeted killing of interleukin-13 (IL-13) receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal model of human disease.
Molecular cancer therapeutics 2004;3(2):137-47.
2004: Claudia Jakubzick; Steven Kunkel; Raj K Puri; Cory M Hogaboam
Therapeutic targeting of IL-4- and IL-13-responsive cells in pulmonary fibrosis.
Immunologic research 2004;30(3):339-49.
2004: Xianmin Zeng; Takumi Miura; Yongquan Luo; Bhaskar Bhattacharya; Brian G Condie; Jia Chen; Irene Ginis; Ian Lyons; Josef Mejido; Raj K Puri; Mahendra S Rao; William J Freed
Properties of pluripotent human embryonic stem cells BG01 and BG02.
Stem cells (Dayton, Ohio) 2004;22(3):292-312.
2003: Ken J Ishii; Koji Kawakami; Ihsan Gursel; Jacqueline Conover; Bharat H Joshi; Dennis M Klinman; Raj K Puri
Antitumor therapy with bacterial DNA and toxin: complete regression of established tumor induced by liposomal CpG oligodeoxynucleotides plus interleukin-13 cytotoxin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6516-22.
2003: Mariko Kawakami; Koji Kawakami; Jan L Kasperbauer; Lucinda L Hinkley; Mamoru Tsukuda; Scott E Strome; Raj K Puri
Interleukin-13 receptor alpha2 chain in human head and neck cancer serves as a unique diagnostic marker.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6381-8.
2003: Mariska C de Jong; George L Scheffer; Henk J Broxterman; Jan Hendrik Hooijberg; Jerry W Slootstra; Rob H Meloen; Robert J Kreitman; Syed R Husain; Bharat H Joshi; Raj K Puri; Rik J Scheper
Multidrug-resistant tumor cells remain sensitive to a recombinant interleukin-4-Pseudomonas exotoxin, except when overexpressing the multidrug resistance protein MRP1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):5009-17.
2003: Syed R Husain; Raj K Puri
Interleukin-13 receptor-directed cytotoxin for malignant glioma therapy: from bench to bedside.
Journal of neuro-oncology 2003;65(1):37-48.
2003: Mariko Kawakami; Koji Kawakami; Raj K Puri
Interleukin-4-Pseudomonas exotoxin chimeric fusion protein for malignant glioma therapy.
Journal of neuro-oncology 2003;65(1):15-25.
2003: Claudia Jakubzick; Esther S Choi; Bharat H Joshi; Michael P Keane; Steven Kunkel; Raj K Puri; Cory M Hogaboam
Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2684-93.
2003: Bharat H Joshi; Pamela Leland; Raj K Puri
Identification and characterization of interleukin-13 receptor in human medulloblastoma and targeting these receptors with interleukin-13-pseudomonas exotoxin fusion protein.
Croatian medical journal 2003;44(4):455-62.
2003: Koji Kawakami; Mariko Kawakami; Syed R Husain; Raj K Puri
Potent antitumor activity of IL-13 cytotoxin in human pancreatic tumors engineered to express IL-13 receptor alpha2 chain in vivo.
Gene therapy 2003;10(13):1116-28.
2003: Koji Kawakami; Mariko Kawakami; Syed R Husain; Raj K Puri
Effect of interleukin (IL)-4 cytotoxin on breast tumor growth after in vivo gene transfer of IL-4 receptor alpha chain.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(5):1826-36.
2003: Claudia Jakubzick; Esther S Choi; Steven Kunkel; Bharat H Joshi; Raj K Puri; Cory M Hogaboam
Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts.
The American journal of pathology 2003;162(5):1475-86.
2003: Syed R Husain; Koji Kawakami; Mariko Kawakami; Raj K Puri
Interleukin-4 receptor-targeted cytotoxin therapy of androgen-dependent and -independent prostate carcinoma in xenograft models.
Molecular cancer therapeutics 2003;2(3):245-54.
2003: Mariko Kawakami; Koji Kawakami; Raj K Puri
Tumor regression mechanisms by IL-13 receptor-targeted cancer therapy involve apoptotic pathways.
International journal of cancer. Journal international du cancer 2003;103(1):45-52.
2002: Koji Kawakami; Mariko Kawakami; Raj K Puri
IL-13 receptor-targeted cytotoxin cancer therapy leads to complete eradication of tumors with the aid of phagocytic cells in nude mice model of human cancer.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):7119-26.
2002: Emanuel F Petricoin; Joseph L Hackett; Lawrence J Lesko; Raj K Puri; Steven I Gutman; Konstantin Chumakov; Janet Woodcock; David W Feigal; Kathy Zoon; Frank D Sistare
Medical applications of microarray technologies: a regulatory science perspective.
Nature genetics 2002;32 Suppl():474-9.
2002: Mariko Kawakami; Koji Kawakami; Vitaly A Stepensky; Richard A Maki; Howard Robin; Wayne Muller; Syed R Husain; Raj K Puri
Interleukin 4 receptor on human lung cancer: a molecular target for cytotoxin therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3503-11.
2002: Mariko Kawakami; Koji Kawakami; Raj K Puri
Intratumor administration of interleukin 13 receptor-targeted cytotoxin induces apoptotic cell death in human malignant glioma tumor xenografts.
Molecular cancer therapeutics 2002;1(12):999-1007.
2002: Claudia Jakubzick; Steven Kunkel; Bharat H Joshi; Raj K Puri; Cory M Hogaboam
Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice.
The American journal of pathology 2002;161(4):1283-97.
2002: Koji Kawakami; Syed R Husain; Mariko Kawakami; Raj K Puri
Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in head and neck cancer xenograft model.
Molecular medicine (Cambridge, Mass.) 2002;8(8):487-94.
2002: Koji Kawakami; Mariko Kawakami; Raj K Puri
Cytokine receptor as a sensitizer for targeted cancer therapy.
Anti-cancer drugs 2002;13(7):693-9.
2002: Koji Kawakami; Mariko Kawakami; Syed R Husain; Raj K Puri
Targeting interleukin-4 receptors for effective pancreatic cancer therapy.
Cancer research 2002;62(13):3575-80.
2002: Bharat H Joshi; Koji Kawakami; Pamela Leland; Raj K Puri
Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1948-56.
2002: Mariko Kawakami; Koji Kawakami; Raj K Puri
Apoptotic pathways of cell death induced by an interleukin-13 receptor-targeted recombinant cytotoxin in head and neck cancer cells.
Cancer immunology, immunotherapy : CII 2002;50(12):691-700.
2002: Kate Blease; Jane M Schuh; Claudia Jakubzick; Nicholas W Lukacs; Steven Kunkel; Bharat H Joshi; Raj K Puri; Mark H Kaplan; Cory M Hogaboam
Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.
The American journal of pathology 2002;160(2):481-90.
2002: Bharat H Joshi; Pamela Leland; J Silber; Robert J Kreitman; Ira Pastan; M Berger; Raj K Puri
IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4-Pseudomonas exotoxin fusion protein.
British journal of cancer 2002;86(2):285-91.
2002: Koji Kawakami; Mariko Kawakami; Pamela Leland; Raj K Puri
Internalization property of interleukin-4 receptor alpha chain increases cytotoxic effect of interleukin-4 receptor-targeted cytotoxin in cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):258-66.
2001: Koji Kawakami; Mariko Kawakami; Philip Snoy; Syed R Husain; Raj K Puri
In vivo overexpression of IL-13 receptor alpha2 chain inhibits tumorigenicity of human breast and pancreatic tumors in immunodeficient mice.
The Journal of experimental medicine 2001;194(12):1743-54.
2001: Kate Blease; Claudia Jakubzick; Jane M Schuh; Bharat H Joshi; Raj K Puri; Cory M Hogaboam
IL-13 fusion cytotoxin ameliorates chronic fungal-induced allergic airway disease in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6583-92.
2001: Bharat H Joshi; Pamela Leland; A Asher; R A Prayson; Frederick Varricchio; Raj K Puri
In situ expression of interleukin-4 (IL-4) receptors in human brain tumors and cytotoxicity of a recombinant IL-4 cytotoxin in primary glioblastoma cell cultures.
Cancer research 2001;61(22):8058-61.
2001: Koji Kawakami; Syed R Husain; R K Bright; Raj K Puri
Gene transfer of interleukin 13 receptor alpha2 chain dramatically enhances the antitumor effect of IL-13 receptor-targeted cytotoxin in human prostate cancer xenografts.
Cancer gene therapy 2001;8(11):861-8.
2001: Koji Kawakami; Mariko Kawakami; Bharat H Joshi; Raj K Puri
Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer.
Cancer research 2001;61(16):6194-200.
2001: Koji Kawakami; F Takeshita; Raj K Puri
Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin (IL)-13 binding component IL-13 receptor alpha 2 chain.
The Journal of biological chemistry 2001;276(27):25114-20.
2001: Yasuo Oshima; Raj K Puri
A novel interleukin 13 (IL-13) antagonist that blocks the biological activity of human IL-13 in immune and nonimmune cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(8):1469-71.
2001: Yasuo Oshima; Raj K Puri
Characterization of a powerful high affinity antagonist that inhibits biological activities of human interleukin-13.
The Journal of biological chemistry 2001;276(18):15185-91.
2001: Koji Kawakami; J Taguchi; T Murata; Raj K Puri
The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway.
Blood 2001;97(9):2673-9.
2001: Syed R Husain; Bharat H Joshi; Raj K Puri
Interleukin-13 receptor as a unique target for anti-glioblastoma therapy.
International journal of cancer. Journal international du cancer 2001;92(2):168-75.
2001: Mariko Kawakami; Pamela Leland; Koji Kawakami; Raj K Puri
Mutation and functional analysis of IL-13 receptors in human malignant glioma cells.
Oncology research 2001;12(11-12):459-67.
2001: Koji Kawakami; Mariko Kawakami; Raj K Puri
Overexpressed cell surface interleukin-4 receptor molecules can be successfully targeted for antitumor cytotoxin therapy.
Critical reviews in immunology 2001;21(1-3):299-310.
2001: Raj K Puri
Cytotoxins directed at interleukin-4 receptors as therapy for human brain tumors.
Methods in molecular biology (Clifton, N.J.) 2001;166():155-76.
2000: Bharat H Joshi; Syed R Husain; Raj K Puri
Preclinical studies with IL-13PE38QQR for therapy of malignant glioma.
Drug news & perspectives 2000;13(10):599-605.
2000: Raj K Puri
IL-4 receptor-directed cytotoxin for therapy of AIDS-associated KS tumors.
Drug news & perspectives 2000;13(7):395-402.
2000: Koji Kawakami; Bharat H Joshi; Raj K Puri
Sensitization of cancer cells to interleukin 13-pseudomonas exotoxin-induced cell death by gene transfer of interleukin 13 receptor alpha chain.
Human gene therapy 2000;11(13):1829-35.
2000: K Kawakami; P Leland; Raj K Puri
Structure, function, and targeting of interleukin 4 receptors on human head and neck cancer cells.
Cancer research 2000;60(11):2981-7.
2000: Syed R Husain; Raj K Puri
Interleukin-13 fusion cytotoxin as a potent targeted agent for AIDS-Kaposi's sarcoma xenograft.
Blood 2000;95(11):3506-13.
2000: Yasuo Oshima; Bharat H Joshi; Raj K Puri
Conversion of interleukin-13 into a high affinity agonist by a single amino acid substitution.
The Journal of biological chemistry 2000;275(19):14375-80.
2000: Pamela Leland; J Taguchi; Syed R Husain; Robert J Kreitman; Ira Pastan; Raj K Puri
Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo.
Molecular medicine (Cambridge, Mass.) 2000;6(3):165-78.
2000: B H Joshi; G E Plautz; Raj K Puri
Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas.
Cancer research 2000;60(5):1168-72.
1999: Syed R Husain; Robert J Kreitman; Ira Pastan; Raj K Puri
Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated Kaposi's sarcoma tumors in xenograft model.
Nature medicine 1999;5(7):817-22.
1999: Raj K Puri
Development of a recombinant interleukin-4-Pseudomonas exotoxin for therapy of glioblastoma.
Toxicologic pathology 1999;27(1):53-7.
1998: Syed R Husain; N Behari; Robert J Kreitman; Ira Pastan; Raj K Puri
Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy.
Cancer research 1998;58(16):3649-53.
1998: T Murata; Syed R Husain; H Mohri; Raj K Puri
Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway.
International immunology 1998;10(8):1103-10.
1998: Waldemar Debinski; Denise M Gibo; Raj K Puri
Novel way to increase targeting specificity to a human glioblastoma-associated receptor for interleukin 13.
International journal of cancer. Journal international du cancer 1998;76(4):547-51.
1998: T Murata; J Taguchi; Raj K Puri
Interleukin-13 receptor alpha' but not alpha chain: a functional component of interleukin-4 receptors.
Blood 1998;91(10):3884-91.
1998: Waldemar Debinski; Denise M Gibo; NI Obiri; A Kealiher; Raj K Puri
Novel anti-brain tumor cytotoxins specific for cancer cells.
Nature biotechnology 1998;16(5):449-53.
1998: R Mehrotra; Frederick Varricchio; Syed R Husain; Raj K Puri
Head and neck cancers, but not benign lesions, express interleukin-4 receptors in situ.
Oncology reports 1998;5(1):45-8.
1997: Gilda G Hillman; E Younes; Daniel W Visscher; Fasahat H Hamzavi; S Kim; J S Lam; EJ Montecillo; E Ali; J Edson Pontes; Raj K Puri; Gabriel P Haas
Inhibition of murine renal carcinoma pulmonary metastases by systemic administration of interferon gamma: mechanism of action and potential for combination with interleukin 4.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(10):1799-806.
1997: T Murata; NI Obiri; Waldemar Debinski; Raj K Puri
Structure of IL-13 receptor: analysis of subunit composition in cancer and immune cells.
Biochemical and biophysical research communications 1997;238(1):90-4.
1997: Atul Maini; Gilda G Hillman; Gabriel P Haas; Ching Y Wang; EJ Montecillo; Fasahat H Hamzavi; J Edson Pontes; Pamela Leland; Ira Pastan; Waldemar Debinski; Raj K Puri
Interleukin-13 receptors on human prostate carcinoma cell lines represent a novel target for a chimeric protein composed of IL-13 and a mutated form of Pseudomonas exotoxin.
The Journal of urology 1997;158(3 Pt 1):948-53.
1997: Subhash Dhawan; Raj K Puri; A Kumar; H Duplan; J M Masson; B B Aggarwal
Human immunodeficiency virus-1-tat protein induces the cell surface expression of endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in human endothelial cells.
Blood 1997;90(4):1535-44.
1997: NI Obiri; T Murata; Waldemar Debinski; Raj K Puri
Modulation of interleukin (IL)-13 binding and signaling by the gammac chain of the IL-2 receptor.
The Journal of biological chemistry 1997;272(32):20251-8.
1997: Syed R Husain; P Gill; Robert J Kreitman; Ira Pastan; Raj K Puri
Interleukin-4 receptor expression on AIDS-associated Kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin.
Molecular medicine (Cambridge, Mass.) 1997;3(5):327-38.
1997: Syed R Husain; NI Obiri; P Gill; T Zheng; Ira Pastan; Waldemar Debinski; Raj K Puri
Receptor for interleukin 13 on AIDS-associated Kaposi's sarcoma cells serves as a new target for a potent Pseudomonas exotoxin-based chimeric toxin protein.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(2):151-6.
1997: T Murata; NI Obiri; Raj K Puri
Human ovarian-carcinoma cell lines express IL-4 and IL-13 receptors: comparison between IL-4- and IL-13-induced signal transduction.
International journal of cancer. Journal international du cancer 1997;70(2):230-40.
1997: NI Obiri; Pamela Leland; T Murata; Waldemar Debinski; Raj K Puri
The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):756-64.
1997: T Murata; Raj K Puri
Comparison of IL-13- and IL-4-induced signaling in EBV-immortalized human B cells.
Cellular immunology 1997;175(1):33-40.
1997: Frederick Varricchio; Syed R Husain; Pamela Leland; P Gill; Raj K Puri
Interleukin-4 receptor expression in vivo on human AIDS-related Kaposi's sarcoma.
Oncology research 1997;9(9):495-503.
1996: Raj K Puri; D S Hoon; Pamela Leland; P Snoy; R W Rand; Ira Pastan; Robert J Kreitman
Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma.
Cancer research 1996;56(24):5631-7.
1996: NI Obiri; Syed R Husain; Waldemar Debinski; Raj K Puri
Interleukin 13 inhibits growth of human renal cell carcinoma cells independently of the p140 interleukin 4 receptor chain.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(10):1743-9.
1996: Syed R Husain; Pamela Leland; B B Aggarwal; Raj K Puri
Transcriptional up-regulation of interleukin 4 receptors by human immunodeficiency virus type 1 tat gene.
AIDS research and human retroviruses 1996;12(14):1349-59.
1996: Waldemar Debinski; R Miner; Pamela Leland; NI Obiri; Raj K Puri
Receptor for interleukin (IL) 13 does not interact with IL4 but receptor for IL4 interacts with IL13 on human glioma cells.
The Journal of biological chemistry 1996;271(37):22428-33.
1996: Raj K Puri; Pamela Leland; NI Obiri; Syed R Husain; J Mule; Ira Pastan; Robert J Kreitman
An improved circularly permuted interleukin 4-toxin is highly cytotoxic to human renal cell carcinoma cells. Introduction of gamma c chain in RCC cells does not improve sensitivity.
Cellular immunology 1996;171(1):80-6.
1996: Raj K Puri; Pamela Leland; NI Obiri; Syed R Husain; Robert J Kreitman; Gabriel P Haas; Ira Pastan; Waldemar Debinski
Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR).
Blood 1996;87(10):4333-9.
1996: T Murata; P D Noguchi; Raj K Puri
IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2972-8.
1995: T Murata; P D Noguchi; Raj K Puri
Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells.
The Journal of biological chemistry 1995;270(51):30829-36.
1995: Waldemar Debinski; NI Obiri; S K Powers; Ira Pastan; Raj K Puri
Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(11):1253-8.
1995: Robert J Kreitman; Raj K Puri; Ira Pastan
Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma.
Cancer research 1995;55(15):3357-63.
1995: Waldemar Debinski; NI Obiri; Ira Pastan; Raj K Puri
A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4.
The Journal of biological chemistry 1995;270(28):16775-80.
1995: NI Obiri; N Tandon; Raj K Puri
Up-regulation of intercellular adhesion molecule 1 (ICAM-1) on human renal cell carcinoma cells by interleukin-4.
International journal of cancer. Journal international du cancer 1995;61(5):635-42.
1995: NI Obiri; Waldemar Debinski; Warren J Leonard; Raj K Puri
Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.
The Journal of biological chemistry 1995;270(15):8797-804.
1995: E Younes; Gabriel P Haas; Daniel W Visscher; J Edson Pontes; Raj K Puri; Gilda G Hillman
Intralesional treatment of established murine primary renal tumor with interleukin-4: localized effect on primary tumor with no impact on metastases.
The Journal of urology 1995;153(2):490-3.
1995: Gilda G Hillman; E Younes; Daniel W Visscher; E Ali; J S Lam; EJ Montecillo; J Edson Pontes; Gabriel P Haas; Raj K Puri
Systemic treatment with interleukin-4 induces regression of pulmonary metastases in a murine renal cell carcinoma model.
Cellular immunology 1995;160(2):257-63.
1995: Raj K Puri
Structure and function of interleukin-4 and its receptor.
Cancer treatment and research 1995;80():143-85.
1995: Pamela Leland; NI Obiri; B B Aggarwal; Raj K Puri
Suramin blocks binding of interleukin-4 to its receptors on human tumor cells and interleukin-4-induced mitogenic response.
Oncology research 1995;7(5):227-35.
1995: Raj K Puri; Pamela Leland; B B Aggarwal
Constitutive expression of human immunodeficiency virus type 1 tat gene inhibits interleukin 2 and interleukin 2 receptor expression in a human CD4+ T lymphoid (H9) cell line.
AIDS research and human retroviruses 1995;11(1):31-40.
1994: Robert J Kreitman; Raj K Puri; Pamela Leland; Byungkook Lee; Ira Pastan
Site-specific conjugation to interleukin 4 containing mutated cysteine residues produces interleukin 4-toxin conjugates with improved binding and activity.
Biochemistry 1994;33(38):11637-44.
1994: Raj K Puri; Pamela Leland; Robert J Kreitman; Ira Pastan
Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein.
International journal of cancer. Journal international du cancer 1994;58(4):574-81.
1994: Robert J Kreitman; Raj K Puri; Ira Pastan
A circularly permuted recombinant interleukin 4 toxin with increased activity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):6889-93.
1994: Gilda G Hillman; Raj K Puri; M A Kukuruga; J Edson Pontes; Gabriel P Haas
Growth and major histocompatibility antigen expression regulation by IL-4, interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) on human renal cell carcinoma.
Clinical and experimental immunology 1994;96(3):476-83.
1994: Raj K Puri; P T Mehrotra; Pamela Leland; Robert J Kreitman; J P Siegel; Ira Pastan
A chimeric protein comprised of IL-4 and Pseudomonas exotoxin is cytotoxic for activated human lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3693-700.
1994: Raj K Puri; Waldemar Debinski; NI Obiri; Robert J Kreitman; Ira Pastan
Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein composed of human interleukin-4 and Pseudomonas exotoxin.
Cellular immunology 1994;154(1):369-79.
1994: NI Obiri; J P Siegel; F Varricchio; Raj K Puri
Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells.
Clinical and experimental immunology 1994;95(1):148-55.
1994: NI Obiri; Raj K Puri
Characterization of interleukin-4 receptors expressed on human renal cell carcinoma cells.
Oncology research 1994;6(9):419-27.
1993: Raj K Puri; Pamela Leland
Tumor necrosis factor upregulates interleukin-4 receptors on murine sarcoma cells.
Biochemical and biophysical research communications 1993;197(3):1424-30.
1993: F Varricchio; NI Obiri; Gabriel P Haas; Raj K Puri
Immunostaining of interleukin-4 receptor on human renal cell carcinoma.
Lymphokine and cytokine research 1993;12(6):465-9.
1993: W Debinski; Raj K Puri; Robert J Kreitman; Ira Pastan
A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin.
The Journal of biological chemistry 1993;268(19):14065-70.
1993: NI Obiri; Gilda G Hillman; Gabriel P Haas; S Sud; Raj K Puri
Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.
The Journal of clinical investigation 1993;91(1):88-93.
1993: Raj K Puri; J P Siegel
Interleukin-4 and cancer therapy.
Cancer investigation 1993;11(4):473-86.
1992: Raj K Puri; D FitzGerald; Pamela Leland; R W Kozak; Ira Pastan
In vitro and in vivo suppression of interleukin-2-activated killer cell activity by chimeric proteins between interleukin-2 and Pseudomonas exotoxin.
Cellular immunology 1992;143(2):324-34.
1992: Raj K Puri; B B Aggarwal
Human immunodeficiency virus type 1 tat gene up-regulates interleukin 4 receptors on a human B-lymphoblastoid cell line.
Cancer research 1992;52(13):3787-90.
1992: S S Ansher; Raj K Puri; W C Thompson; W H Habig
The effects of interleukin 2 and alpha-interferon administration on hepatic drug metabolism in mice.
Cancer research 1992;52(2):262-6.
1991: Raj K Puri; M Ogata; P Leland; G M Feldman; D FitzGerald; Ira Pastan
Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin.
Cancer research 1991;51(11):3011-7.
1991: R A Wong; Richard B Alexander; Raj K Puri; STEVEN ROSENBERG
In vivo proliferation of adoptively transferred tumor-infiltrating lymphocytes in mice.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(2):120-30.
1991: Raj K Puri; P Leland; A Razzaque
Antigen(s)-specific tumour-infiltrating lymphocytes from tumour induced by human herpes virus-6 (HHV-6) DNA transfected NIH 3T3 transformants.
Clinical and experimental immunology 1991;83(1):96-101.
1990: R W Kozak; Haya Lorberboum-Galski; L Jones; Raj K Puri; M C Willingham; T Malek; David J FitzGerald; Thomas Waldmann; Ira Pastan
IL-2-PE40 prevents the development of tumors in mice injected with IL-2 receptor expressing EL4 transfectant tumor cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(8):2766-71.
1990: Raj K Puri; William D Travis; STEVEN ROSENBERG
In vivo administration of interferon alpha and interleukin 2 induces proliferation of lymphoid cells in the organs of mice.
Cancer research 1990;50(17):5543-50.
1990: Raj K Puri; DS Finbloom; Pamela Leland; Howard Mostowski; J P Siegel
Expression of high-affinity IL-4 receptors on murine tumour infiltrating lymphocytes and their up-regulation by IL-2.
Immunology 1990;70(4):492-7.
1989: Raj K Puri; William D Travis; STEVEN ROSENBERG
Decrease in interleukin 2-induced vascular leakage in the lungs of mice by administration of recombinant interleukin 1 alpha in vivo.
Cancer research 1989;49(4):969-76.
1989: Raj K Puri; STEVEN ROSENBERG
Combined effects of interferon alpha and interleukin 2 on the induction of a vascular leak syndrome in mice.
Cancer immunology, immunotherapy : CII 1989;28(4):267-74.