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Haig Kazazian

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Szilvia Solyom; Kyle R Upton; Sarah J Wheelan; David A Largaespada; Heather H Nelson; Eric P Rahrmann; Ruchi Shukla; David F Sigmon; Michael B Burns; Alex Casella; Tara Doucet; Bracha Erlanger; Adam D Ewing; Geoffrey J Faulkner; Reuben S Harris; Haig Kazazian
Extensive somatic L1 retrotransposition in colorectal tumors.
Dustin C Hancks; Ling E Cheung; Prabhat K Mandal; Haig Kazazian
The minimal active human SVA retrotransposon requires only the 5'-hexamer and Alu-like domains.
Dustin C Hancks; Haig Kazazian
Active human retrotransposons: variation and disease.

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All Publications

2012: Szilvia Solyom; Kyle R Upton; Sarah J Wheelan; David A Largaespada; Heather H Nelson; Eric P Rahrmann; Ruchi Shukla; David F Sigmon; Michael B Burns; Alex Casella; Tara Doucet; Bracha Erlanger; Adam D Ewing; Geoffrey J Faulkner; Reuben S Harris; Haig Kazazian
Extensive somatic L1 retrotransposition in colorectal tumors.
Genome research 2012;22(12):2328-38.
2012: Dustin C Hancks; Ling E Cheung; Prabhat K Mandal; Haig Kazazian
The minimal active human SVA retrotransposon requires only the 5'-hexamer and Alu-like domains.
Molecular and cellular biology 2012;32(22):4718-26.
2012: Dustin C Hancks; Haig Kazazian
Active human retrotransposons: variation and disease.
Current opinion in genetics & development 2012;22(3):191-203.
2012: Szilvia Solyom; Yasuhiro Takeshima; Adam D Ewing; Dustin C Hancks; Masafumi Matsuo; Hiroyuki Awano; Haig Kazazian
Pathogenic orphan transduction created by a nonreference LINE-1 retrotransposon.
Human mutation 2012;33(2):369-71.
2012: John L Goodier; Ling E Cheung; Haig Kazazian
MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.
PLoS genetics 2012;8(10):e1002941.
2012: Szilvia Solyom; Haig Kazazian
Mobile elements in the human genome: implications for disease.
Genome medicine 2012;4(2):12.
2011: Dustin C Hancks; Ling E Cheung; John L Goodier; Prabhat K Mandal; Haig Kazazian
Retrotransposition of marked SVA elements by human L1s in cultured cells.
Human molecular genetics 2011;20(17):3386-400.
2011: Adam D Ewing; Haig Kazazian
Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans.
Genome research 2011;21(6):985-90.
2011: Denise E Sabatino; Amy M Lange; Ekaterina S Altynova; Rita Sarkar; Shangzhen Zhou; Elizabeth P Merricks; Helen G Franck; Timothy C Nichols; Valder R Arruda; Haig Kazazian
Efficacy and safety of long-term prophylaxis in severe hemophilia A dogs following liver gene therapy using AAV vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):442-9.
2011: Haig Kazazian
Mobile DNA transposition in somatic cells.
BMC biology 2011;9():62.
2010: Jonathan D Finn; Margareth C Ozelo; Denise E Sabatino; Helen W G Franck; Elizabeth P Merricks; Julie M Crudele; Shangzhen Zhou; Haig Kazazian ; David Lillicrap; Timothy C Nichols; Valder R Arruda
Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.
Blood 2010;116(26):5842-8.
2010: Adam D Ewing; Haig Kazazian
High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes.
Genome research 2010;20(9):1262-70.
2010: Dustin C Hancks; Haig Kazazian
SVA retrotransposons: Evolution and genetic instability.
Seminars in cancer biology 2010;20(4):234-45.
2010: John L Goodier; Prabhat K Mandal; Lili Zhang; Haig Kazazian
Discrete subcellular partitioning of human retrotransposon RNAs despite a common mechanism of genome insertion.
Human molecular genetics 2010;19(9):1712-25.
2009: Denise E Sabatino; Christian Furlan Freguia; Raffaella Toso; Andrey Santos; Elizabeth P Merricks; Haig Kazazian ; Timothy C Nichols; Rodney M Camire; Valder R Arruda
Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model.
Blood 2009;114(20):4562-5.
2009: Dustin C Hancks; Adam D Ewing; Jesse E Chen; Katsushi Tokunaga; Haig Kazazian
Exon-trapping mediated by the human retrotransposon SVA.
Genome research 2009;19(11):1983-91.
2009: Sanjida H Rangwala; Haig Kazazian
The L1 retrotransposition assay: a retrospective and toolkit.
Methods (San Diego, Calif.) 2009;49(3):219-26.
2009: Hiroki Kano; Irene Godoy; Christine Courtney; Melissa R Vetter; George Gerton; Eric M Ostertag; Haig Kazazian
L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism.
Genes & development 2009;23(11):1303-12.
2009: Haig Kazazian
Allan Award Lecture: on jumping fields and "jumping genes".
American journal of human genetics 2009;84(2):105-14.
2009: Sanjida H Rangwala; Lili Zhang; Haig Kazazian
Many LINE1 elements contribute to the transcriptome of human somatic cells.
Genome biology 2009;10(9):R100.
2008: Prabhat K Mandal; Haig Kazazian
SnapShot: Vertebrate transposons.
Cell 2008;135(1):192-192.e1.
2008: John L Goodier; Haig Kazazian
Retrotransposons revisited: the restraint and rehabilitation of parasites.
Cell 2008;135(1):23-35.
2008: Richard G H Cotton; Haig Kazazian ; Garry R Cutting; Mark Paalman
In memoriam: Victor A. McKusick (1921-2008).
Human mutation 2008;29(10):1169-70.
2007: John L Goodier; Lili Zhang; Melissa R Vetter; Haig Kazazian
LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex.
Molecular and cellular biology 2007;27(18):6469-83.
2007: Daria V Babushok; Kazuhiko Ohshima; Eric M Ostertag; Xinsheng Chen; Yanfeng Wang; Prabhat K Mandal; Norihiro Okada; Charles S Abrams; Haig Kazazian
A novel testis ubiquitin-binding protein gene arose by exon shuffling in hominoids.
Genome research 2007;17(8):1129-38.
2007: José A J M van den Hurk; Iwan C Meij; Maria del Carmen Seleme; Hiroki Kano; Konstantinos Nikopoulos; Lies Hoefsloot; Erik A Sistermans; Ilse J de Wijs; Arijit Mukhopadhyay; Astrid S Plomp; Paulus T V M de Jong; Haig Kazazian ; Frans P M Cremers
L1 retrotransposition can occur early in human embryonic development.
Human molecular genetics 2007;16(13):1587-92.
2007: Daria V Babushok; Haig Kazazian
Progress in understanding the biology of the human mutagen LINE-1.
Human mutation 2007;28(6):527-39.
2007: Daria V Babushok; Eric M Ostertag; Haig Kazazian
Current topics in genome evolution: molecular mechanisms of new gene formation.
Cellular and molecular life sciences : CMLS 2007;64(5):542-54.
2007: Randy J Chandler; Jennifer Sloan; Hong Fu; Matthew Tsai; Sally Stabler; Robert Allen; Klaus kaestner; Haig Kazazian ; Charles Venditti
Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle.
BMC medical genetics 2007;8():64.
2006: Nuo Yang; Haig Kazazian
L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells.
Nature structural & molecular biology 2006;13(9):763-71.
2006: Randy J Chandler; Vijay Aswani; Matthew S Tsai; Marni Falk; Natasha Wehrli; Sally Stabler; Robert Allen; Margaret Sedensky; Haig Kazazian ; Charles Venditti
Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism.
Molecular genetics and metabolism 2006;89(1-2):64-73.
2006: Shuji Kubo; Maria del Carmen Seleme; Harris S Soifer; José Luis Garcia Perez; John V Moran; Haig Kazazian ; Noriyuki Kasahara
L1 retrotransposition in nondividing and primary human somatic cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8036-41.
2006: Maria del Carmen Seleme; Melissa R Vetter; Richard Cordaux; Laurel Bastone; Mark A Batzer; Haig Kazazian
Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(17):6611-6.
2006: Rita Sarkar; Melinda Mucci; Sankar Addya; Renee Tetreault; Dwight A Bellinger; Timothy C Nichols; Haig Kazazian
Long-term efficacy of adeno-associated virus serotypes 8 and 9 in hemophilia a dogs and mice.
Human gene therapy 2006;17(4):427-39.
2006: Daria V Babushok; Eric M Ostertag; Christine E Courtney; Janice M Choi; Haig Kazazian
L1 integration in a transgenic mouse model.
Genome research 2006;16(2):240-50.
2005: Eric M Ostertag; Haig Kazazian
Genetics: LINEs in mind.
Nature 2005;435(7044):890-1.
2005: Vivek S Purohit; Karthik Ramani; Rita Sarkar; Haig Kazazian ; Sathyamangalam V Balasubramanian
Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex.
The Journal of biological chemistry 2005;280(18):17593-600.
2005: Mary Ellen Conley; Julie D Partain; Shannon M Norland; Sheila A Shurtleff; Haig Kazazian
Two independent retrotransposon insertions at the same site within the coding region of BTK.
Human mutation 2005;25(3):324-5.
2005: Nuo Yang; Lin Zhang; Haig Kazazian
L1 retrotransposon-mediated stable gene silencing.
Nucleic acids research 2005;33(6):e57.
2004: John L Goodier; Eric M Ostertag; Kurt A Engleka; Maria del Carmen Seleme; Haig Kazazian
A potential role for the nucleolus in L1 retrotransposition.
Human molecular genetics 2004;13(10):1041-8.
2004: Haig Kazazian
Mobile elements: drivers of genome evolution.
Science (New York, N.Y.) 2004;303(5664):1626-32.
2004: Rita Sarkar; Renee Tetreault; Guangping Gao; Lili Wang; Peter Bell; Randy J Chandler; James M Wilson; Haig Kazazian
Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype.
Blood 2004;103(4):1253-60.
2004: Alexander H Farley; Eline T Luning Prak; Haig Kazazian
More active human L1 retrotransposons produce longer insertions.
Nucleic acids research 2004;32(2):502-10.
2003: Prescott L Deininger; John V Moran; Mark A Batzer; Haig Kazazian
Mobile elements and mammalian genome evolution.
Current opinion in genetics & development 2003;13(6):651-8.
2003: Eric M Ostertag; John L Goodier; Yue Zhang; Haig Kazazian
SVA elements are nonautonomous retrotransposons that cause disease in humans.
American journal of human genetics 2003;73(6):1444-51.
2003: Sheila M Lutz; Bethaney J Vincent; Haig Kazazian ; Mark A Batzer; John V Moran
Allelic heterogeneity in LINE-1 retrotransposition activity.
American journal of human genetics 2003;73(6):1431-7.
2003: Ciaran D Scallan; Tongyao Liu; Amy E Parker; Susannah Patarroyo-White; Haifeng Chen; Haiyan Jiang; Joseph Vargas; Dea Nagy; Sharon K Powell; J Fraser Wright; Rita Sarkar; Haig Kazazian ; Alan McClelland; Linda B Couto
Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.
Blood 2003;102(12):3919-26.
2003: Nuo Yang; Lin Zhang; Yue Zhang; Haig Kazazian
An important role for RUNX3 in human L1 transcription and retrotransposition.
Nucleic acids research 2003;31(16):4929-40.
2003: Ingrid Hrachovinová; Beatrice Cambien; Ali Hafezi-Moghadam; János Kappelmayer; Raymond T Camphausen; Angela Widom; Lijun Xia; Haig Kazazian ; Robert G Schaub; Rodger P McEver; Denisa D Wagner
Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.
Nature medicine 2003;9(8):1020-5.
2003: Brook Brouha; Joshua Schustak; Richard M Badge; Sheila Lutz-Prigge; Alexander H Farley; John V Moran; Haig Kazazian
Hot L1s account for the bulk of retrotransposition in the human population.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5280-5.
2003: Eline T Luning Prak; Allen W Dodson; Evan A Farkash; Haig Kazazian
Tracking an embryonic L1 retrotransposition event.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1832-7.
2003: Rita Sarkar; Weidong Xiao; Haig Kazazian
A single adeno-associated virus (AAV)-murine factor VIII vector partially corrects the hemophilia A phenotype.
Journal of thrombosis and haemostasis : JTH 2003;1(2):220-6.
2003: Cathryn Mah; Rita Sarkar; Irene Zolotukhin; Mary Schleissing; Xiao Xiao; Haig Kazazian ; Barry J Byrne
Dual vectors expressing murine factor VIII result in sustained correction of hemophilia A mice.
Human gene therapy 2003;14(2):143-52.
2002: Eric M Ostertag; Ralph J DeBerardinis; John L Goodier; Yue Zhang; Nuo Yang; George Gerton; Haig Kazazian
A mouse model of human L1 retrotransposition.
Nature genetics 2002;32(4):655-60.
2002: Haig Kazazian ; John L Goodier
LINE drive. retrotransposition and genome instability.
Cell 2002;110(3):277-80.
2002: Brook Brouha; Christof Meischl; Eric M Ostertag; Martin de Boer; Yue Zhang; Herman J Neijens; Dirk Roos; Haig Kazazian
Evidence consistent with human L1 retrotransposition in maternal meiosis I.
American journal of human genetics 2002;71(2):327-36.
2001: Eric M Ostertag; Haig Kazazian
Twin priming: a proposed mechanism for the creation of inversions in L1 retrotransposition.
Genome research 2001;11(12):2059-65.
2001: John L Goodier; Eric M Ostertag; K Du; Haig Kazazian
A novel active L1 retrotransposon subfamily in the mouse.
Genome research 2001;11(10):1677-85.
2001: Harris S Soifer; C Higo; Haig Kazazian ; John V Moran; Kohnosuke Mitani; Noriyuki Kasahara
Stable integration of transgenes delivered by a retrotransposon-adenovirus hybrid vector.
Human gene therapy 2001;12(11):1417-28.
2001: Naomi B Haas; J M Grabowski; J North; John V Moran; Haig Kazazian ; John B E Burch
Subfamilies of CR1 non-LTR retrotransposons have different 5'UTR sequences but are otherwise conserved.
Gene 2001;265(1-2):175-83.
2001: W Wei; Nicolas Gilbert; S L Ooi; Joseph F Lawler; Eric M Ostertag; Haig Kazazian ; Jef Boeke; John V Moran
Human L1 retrotransposition: cis preference versus trans complementation.
Molecular and cellular biology 2001;21(4):1429-39.
2001: Haig Kazazian
Retrotransposon insertions in germ cells and somatic cells.
Developments in biologicals 2001;106():307-13; discussion 313-4, 317-29.
2001: Eric M Ostertag; Haig Kazazian
Biology of mammalian L1 retrotransposons.
Annual review of genetics 2001;35():501-38.
2000: Eline T Luning Prak; Haig Kazazian
Mobile elements and the human genome.
Nature reviews. Genetics 2000;1(2):134-44.
2000: Ann E Pulver; Jennifer Gladys Mulle; Gerald Nestadt; Karen L Swartz; Jean-Louis Blouin; BA Dombroski; Kung-Yee Liang; D E Housman; Haig Kazazian ; Stylianos E Antonarakis; Virginia K Lasseter; Paula S Wolyniec; Mary H Thornquist; John A McGrath
Genetic heterogeneity in schizophrenia: stratification of genome scan data using co-segregating related phenotypes.
Molecular psychiatry 2000;5(6):650-3.
2000: Haig Kazazian
Genetics. L1 retrotransposons shape the mammalian genome.
Science (New York, N.Y.) 2000;289(5482):1152-3.
2000: Steven S Fakharzadeh; Yi Zhang; Rita Sarkar; Haig Kazazian
Correction of the coagulation defect in hemophilia A mice through factor VIII expression in skin.
Blood 2000;95(9):2799-805.
2000: Rita Sarkar; Guang-Ping Gao; Narendra Chirmule; John Tazelaar; Haig Kazazian
Partial correction of murine hemophilia A with neo-antigenic murine factor VIII.
Human gene therapy 2000;11(6):881-94.
2000: Eric M Ostertag; Eline T Luning Prak; Ralph J DeBerardinis; John V Moran; Haig Kazazian
Determination of L1 retrotransposition kinetics in cultured cells.
Nucleic acids research 2000;28(6):1418-23.
2000: John L Goodier; Eric M Ostertag; Haig Kazazian
Transduction of 3'-flanking sequences is common in L1 retrotransposition.
Human molecular genetics 2000;9(4):653-7.
2000: Steven S Fakharzadeh; Haig Kazazian
Correlation between factor VIII genotype and inhibitor development in hemophilia A.
Seminars in thrombosis and hemostasis 2000;26(2):167-71.
1999: Gerald S Lipshutz; Rajabrata Sarkar; Linda Flebbe-Rehwaldt; Haig Kazazian ; Karin M L Gaensler
Short-term correction of factor VIII deficiency in a murine model of hemophilia A after delivery of adenovirus murine factor VIII in utero.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13324-9.
1999: Stylianos E Antonarakis; Jean-Louis Blouin; Virginia K Lasseter; Corinne Gehrig; Uppala Radhakrishna; Gerald Nestadt; DE Housman; Haig Kazazian ; Katalin Kalman; George A Gutman; Emmanuelle Fantino; K George Chandy; J Jay Gargus; Ann E Pulver
Lack of linkage or association between schizophrenia and the polymorphic trinucleotide repeat within the KCNN3 gene on chromosome 1q21.
American journal of medical genetics 1999;88(4):348-51.
1999: M L Kimberland; V Divoky; Josef T Prchal; U Schwahn; W Berger; Haig Kazazian
Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells.
Human molecular genetics 1999;8(8):1557-60.
1999: Haig Kazazian
An estimated frequency of endogenous insertional mutations in humans.
Nature genetics 1999;22(2):130.
1999: Logos Curtis; Jean-Louis Blouin; Uppala Radhakrishna; Corinne Gehrig; Virginia K Lasseter; Paula S Wolyniec; Gerald Nestadt; BA Dombroski; Haig Kazazian ; Ann E Pulver; DE Housman; D Bertrand; Stylianos E Antonarakis
No evidence for linkage between schizophrenia and markers at chromosome 15q13-14.
American journal of medical genetics 1999;88(2):109-12.
1999: Ralph J DeBerardinis; Haig Kazazian
Analysis of the promoter from an expanding mouse retrotransposon subfamily.
Genomics 1999;56(3):317-23.
1999: John V Moran; Ralph J DeBerardinis; Haig Kazazian
Exon shuffling by L1 retrotransposition.
Science (New York, N.Y.) 1999;283(5407):1530-4.
1999: J Qian; M Borovok; L Bi; Haig Kazazian ; Leon Hoyer
Inhibitor antibody development and T cell response to human factor VIII in murine hemophilia A.
Thrombosis and haemostasis 1999;81(2):240-4.
1998: Ralph J DeBerardinis; John L Goodier; Eric M Ostertag; Haig Kazazian
Rapid amplification of a retrotransposon subfamily is evolving the mouse genome.
Nature genetics 1998;20(3):288-90.
1998: Ralph J DeBerardinis; Haig Kazazian
Full-length L1 elements have arisen recently in the same 1-kb region of the gorilla and human genomes.
Journal of molecular evolution 1998;47(3):292-301.
1998: Jean-Louis Blouin; BA Dombroski; Swapan K Nath; Virginia K Lasseter; Paula S Wolyniec; Gerald Nestadt; Mary H Thornquist; G Ullrich; J McGrath; L Kasch; M Lamacz; M G Thomas; Corinne Gehrig; Uppala Radhakrishna; S E Snyder; K G Balk; Karin Neufeld; Karen L Swartz; N DeMarchi; G N Papadimitriou; Dimitris G Dikeos; C N Stefanis; Aravinda Chakravarti; Barton Childs; DE Housman; Haig Kazazian ; Stylianos E Antonarakis; Ann E Pulver
Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21.
Nature genetics 1998;20(1):70-3.
1998: Haig Kazazian
Mobile elements and disease.
Current opinion in genetics & development 1998;8(3):343-50.
1998: Haig Kazazian ; John V Moran
The impact of L1 retrotransposons on the human genome.
Nature genetics 1998;19(1):19-24.
1998: Maria Karayiorgou; Joseph A Gogos; Brandi L Galke; Paula S Wolyniec; Gerald Nestadt; Stylianos E Antonarakis; Haig Kazazian ; D E Housman; Ann E Pulver
Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility.
Biological psychiatry 1998;43(6):425-31.
1998: T P Naas; Ralph J DeBerardinis; John V Moran; Eric M Ostertag; Stephen Kingsmore; Michael F Seldin; Y Hayashizaki; S L Martin; Haig Kazazian
An actively retrotransposing, novel subfamily of mouse L1 elements.
The EMBO journal 1998;17(2):590-7.
1998: K Amano; R Sarkar; S Pemberton; Geoffrey Kemball-Cook; Haig Kazazian ; Randal J Kaufman
The molecular basis for cross-reacting material-positive hemophilia A due to missense mutations within the A2-domain of factor VIII.
Blood 1998;91(2):538-48.
1998: B D M Theophilus; MOHAMMAD ENAYAT; M Higuchi; Haig Kazazian ; Stylianos Antonarakis; Frank G H Hill
Independent occurrence of the novel Arg2163 to His mutation in the factor VIII gene in three unrelated families with haemophila A with different phenotypes. Mutations in brief no. 126. Online.
Human mutation 1998;11(4):334.
1997: D M Sassaman; BA Dombroski; John V Moran; M L Kimberland; T P Naas; Ralph J DeBerardinis; A Gabriel; Gary Swergold; Haig Kazazian
Many human L1 elements are capable of retrotransposition.
Nature genetics 1997;16(1):37-43.
1997: M Young; H Inaba; Leon Hoyer; M Higuchi; Haig Kazazian ; Stylianos E Antonarakis
Partial correction of a severe molecular defect in hemophilia A, because of errors during expression of the factor VIII gene.
American journal of human genetics 1997;60(3):565-73.
1996: John V Moran; Susan E Holmes; T P Naas; Ralph J DeBerardinis; Jef Boeke; Haig Kazazian
High frequency retrotransposition in cultured mammalian cells.
Cell 1996;87(5):917-27.
1996: Q Feng; John V Moran; Haig Kazazian ; Jef Boeke
Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition.
Cell 1996;87(5):905-16.
1996: L Bi; R Sarkar; T Naas; Ann M Lawler; J Pain; S L Shumaker; Vahe Bedian; Haig Kazazian
Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies.
Blood 1996;88(9):3446-50.
1996: Starlene Loader; P Caldwell; A Kozyra; Jeffrey C Levenkron; Corinne D Boehm; Haig Kazazian ; Peter T Rowley
Cystic fibrosis carrier population screening in the primary care setting.
American journal of human genetics 1996;59(1):234-47.
1996: Howard A Pearson; A R Cohen; Patricia J Giardina; Haig Kazazian
The changing profile of homozygous beta-thalassemia: demography, ethnicity, and age distribution of current North American patients and changes in two decades.
Pediatrics 1996;97(3):352-6.
1996: M Gill; Homero Vallada; David Collier; Pak Sham; Peter Holmans; Robin Murray; Peter McGuffin; Shinichiro Nanko; Michael J Owen; S Antonarakis; D Housman; Haig Kazazian ; Gerald Nestadt; Ann E Pulver; R E Straub; C J MacLean; D Walsh; K S Kendler; L DeLisi; Mihael H Polymeropoulos; Hilary Coon; William Byerley; R Lofthouse; E Gershon; C M Read
A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).
American journal of medical genetics 1996;67(1):40-5.
1996: Maria Karayiorgou; Joseph A Gogos; Brandi L Galke; J A Jeffery; Gerald Nestadt; Paula S Wolyniec; Stylianos Antonarakis; Haig Kazazian ; David E Housman; D A Driscoll; Ann E Pulver
Genotype and phenotype analysis at the 22q11 schizophrenia susceptibility locus.
Cold Spring Harbor symposia on quantitative biology 1996;61():835-43.
1996: Ann E Pulver; Paula S Wolyniec; D Housman; Haig Kazazian ; Stylianos Antonarakis; Gerald Nestadt; Virginia K Lasseter; J A McGrath; B Dombroski; Maria Karayiorgou; C Ton; Jean-Louis Blouin; L Kempf
The Johns Hopkins University Collaborative Schizophrenia Study: an epidemiologic-genetic approach to test the heterogeneity hypothesis and identify schizophrenia susceptibility genes.
Cold Spring Harbor symposia on quantitative biology 1996;61():797-814.
1996: AI Wacey; Geoffrey Kemball-Cook; Haig Kazazian ; Stylianos Antonarakis; R Schwaab; Peter F Lindley; Edward G D Tuddenham
The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database: HAMSTeRS.
Nucleic acids research 1996;24(1):100-2.
1995: Stylianos Antonarakis; Jean-Louis Blouin; Ann E Pulver; Paula S Wolyniec; Virginia K Lasseter; Gerald Nestadt; L Kasch; R Babb; Haig Kazazian ; B Dombroski
Schizophrenia susceptibility and chromosome 6p24-22.
Nature genetics 1995;11(3):235-6.
1995: Stylianos Antonarakis; Judith P. Rossiter; M Young; J Horst; P de Moerloose; S S Sommer; Rhett P Ketterling; Haig Kazazian ; Claude Négrier; Christine Vinciguerra; Jane Gitschier; Michel Goossens; Emmanuelle Girodon; N Ghanem; F Plassa; Jean-Maurice Lavergne; M Vidaud; J M Costa; Yves Laurian; S W Lin; S R Lin; M C Shen; David Lillicrap; S A Taylor; S Windsor; Sophie Valleix; Khedoudja Nafa; Y Sultan; Marc Delpech; C L Vnencak-Jones; J A Phillips; R C Ljung; E Koumbarelis; AE Gialeraki; Titika Mandalaki; P Vincent Jenkins; P W Collins; K John Pasi; Anne C Goodeve; Ian R Peake; F Eric Preston; Marianne Schwartz; E Scheibel; Jørgen Ingerslev; D N Cooper; D S Millar; V V Kakkar; F Giannelli; J A Naylor; E F Tizzano; Montserrat Baiget; M Domenech; Carme Altisent; J Tusell; M Beneyto; J I Lorenzo; Christine Gaucher; Claudine Mazurier; Kathelijne Peerlinck; Gert Matthijs; J J Cassiman; J Vermylen; Pier Giorgio Mori; M Acquila; Daniela Caprino; H Inaba
Factor VIII gene inversions in severe hemophilia A: results of an international consortium study.
Blood 1995;86(6):2206-12.
1995: L Bi; Ann M Lawler; Stylianos Antonarakis; K A High; John D Gearhart; Haig Kazazian
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.
Nature genetics 1995;10(1):119-21.
1995: Virginia K Lasseter; Ann E Pulver; Paula S Wolyniec; Gerald Nestadt; Deborah A Meyers; Maria Karayiorgou; D Housman; S Antonarakis; Haig Kazazian ; L Kasch
Follow-up report of potential linkage for schizophrenia on chromosome 22q: Part 3.
American journal of medical genetics 1995;60(2):172-3.
1995: Stylianos Antonarakis; Haig Kazazian ; Jane Gitschier; P Hutter; Philippe de Moerloose; Michael Morris
Molecular etiology of factor VIII deficiency in hemophilia A.
Advances in experimental medicine and biology 1995;386():19-34.
1995: Stylianos Antonarakis; Haig Kazazian ; E G Tuddenham
Molecular etiology of factor VIII deficiency in hemophilia A.
Human mutation 1995;5(1):1-22.
1995: M L Kimberland; Corinne D Boehm; Haig Kazazian
Two novel beta-thalassemia alleles: poly A signal (AATAAA-->AAAA) and -92 C-->T.
Human mutation 1995;5(3):275-6.
1994: Judith P. Rossiter; Karin J Blakemore; Thomas S Kickler; L M Kasch; A N Khouzami; Eva K Pressman; A C Sciscione; Haig Kazazian
The use of polymerase chain reaction to determine fetal RhD status.
American journal of obstetrics and gynecology 1994;171(4):1047-51.
1994: B A Dombroski; Q Feng; S L Mathias; D M Sassaman; Alan F Scott; Haig Kazazian ; Jef Boeke
An in vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae.
Molecular and cellular biology 1994;14(7):4485-92.
1994: G Balta; H E Brickner; S Takegawa; Haig Kazazian ; T Papayannopoulou; B G Forget; George F Atweh
Increased expression of the G gamma and A gamma globin genes associated with a mutation in the A gamma enhancer.
Blood 1994;83(12):3727-37.
1994: Susan E Holmes; B A Dombroski; C M Krebs; Corinne D Boehm; Haig Kazazian
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion.
Nature genetics 1994;7(2):143-8.
1994: Ann E Pulver; Maria Karayiorgou; Paula S Wolyniec; Virginia K Lasseter; L Kasch; Gerald Nestadt; S Antonarakis; D Housman; Haig Kazazian ; Deborah A Meyers
Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1.
American journal of medical genetics 1994;54(1):36-43.
1994: Ann E Pulver; Maria Karayiorgou; Virginia K Lasseter; Paula S Wolyniec; L Kasch; S Antonarakis; D Housman; Haig Kazazian ; Deborah A Meyers; Gerald Nestadt
Follow-up of a report of a potential linkage for schizophrenia on chromosome 22q12-q13.1: Part 2.
American journal of medical genetics 1994;54(1):44-50.
1994: Allan L Reiss; Haig Kazazian ; C M Krebs; A McAughan; Corinne D Boehm; Michael T Abrams; D L Nelson
Frequency and stability of the fragile X premutation.
Human molecular genetics 1994;3(3):393-8.
1994: G Garewal; C W Fearon; T C Warren; N Marwaha; R K Marwaha; C Mahadik; Haig Kazazian
The molecular basis of beta thalassaemia in Punjabi and Maharashtran Indians includes a multilocus aetiology involving triplicated alpha-globin loci.
British journal of haematology 1994;86(2):372-6.
1994: Haig Kazazian
The new genetics.
Science (New York, N.Y.) 1994;263(5144):255-6.
1993: D Lakich; Haig Kazazian ; Stylianos Antonarakis; Jane Gitschier
Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A.
Nature genetics 1993;5(3):236-41.
1993: B A Dombroski; Alan F Scott; Haig Kazazian
Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable element.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6513-7.
1993: M J McGinniss; C Rosenberg; Gail Stetten; Albert Schinzel; Franz Binkert; Michael B Petersen; William G Kearns; Haig Kazazian ; P L Pearson; Stylianos Antonarakis
Unbalanced translocation, t(18;21), detected by fluorescence in situ hybridization (FISH) in a child with 18q- syndrome and a ring chromosome 21.
American journal of medical genetics 1993;46(6):647-51.
1993: Haig Kazazian
The molecular basis of hemophilia A and the present status of carrier and antenatal diagnosis of the disease.
Thrombosis and haemostasis 1993;70(1):60-2.
1993: Allan L Reiss; LS Freund; Michael T Abrams; Corinne D Boehm; Haig Kazazian
Neurobehavioral effects of the fragile X premutation in adult women: a controlled study.
American journal of human genetics 1993;52(5):884-94.
1993: Haig Kazazian ; Alan F Scott
"Copy and paste" transposable elements in the human genome.
The Journal of clinical investigation 1993;91(5):1859-60.
1993: Barbara R Migeon; M J McGinniss; S E Antonarakis; Joyce Axelman; B A Stasiowski; H Youssoufian; William G Kearns; A Chung; P L Pearson; Haig Kazazian
Severe hemophilia A in a female by cryptic translocation: order and orientation of factor VIII within Xq28.
Genomics 1993;16(1):20-5.
1993: M J McGinniss; Haig Kazazian ; Leon Hoyer; L Bi; H Inaba; S E Antonarakis
Spectrum of mutations in CRM-positive and CRM-reduced hemophilia A.
Genomics 1993;15(2):392-8.
1993: I R Hussein; Samia A Temtamy; A el-Beshlawy; C Fearon; Z Shalaby; G Vassilopoulos; Haig Kazazian
Molecular characterization of beta-thalassemia in Egyptians.
Human mutation 1993;2(1):48-52.
1993: Ariella Oppenheim; V Oron; Dvora Filon; C C Fearon; Eliezer A Rachmilewitz; Haig Kazazian ; Deborah Rund
Sporadic alleles, including a novel mutation, characterize beta-thalassemia in Ashkenazi Jews.
Human mutation 1993;2(2):155-7.
1992: Myron Miller; Corinne D Boehm; M Cotton; Haig Kazazian
Usefulness of a CACA repeat polymorphism in genotype assignments in Duchenne/Becker muscular dystrophy.
American journal of medical genetics 1992;44(4):473-6.
1992: E P Economou; Haig Kazazian ; S E Antonarakis
Detection of mutations in the factor VIII gene using single-stranded conformational polymorphism (SSCP).
Genomics 1992;13(3):909-11.
1992: A M Aly; M Higuchi; C K Kasper; Haig Kazazian ; S E Antonarakis; Leon Hoyer
Hemophilia A due to mutations that create new N-glycosylation sites.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):4933-7.
1992: Haig Kazazian ; C E Dowling; R L Hurwitz; M Coleman; A Stopeck; J G Adams
Dominant thalassemia-like phenotypes associated with mutations in exon 3 of the beta-globin gene.
Blood 1992;79(11):3014-8.
1992: Deborah Rund; C Dowling; K Najjar; Eliezer A Rachmilewitz; Haig Kazazian ; Ariella Oppenheim
Two mutations in the beta-globin polyadenylylation signal reveal extended transcripts and new RNA polyadenylylation sites.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4324-8.
1992: M Renda; Aurelio Maggio; T C Warren; Haig Kazazian
Detection of an IVS-1 3' end (G-C) beta-thalassemia mutation in the AG invariant dinucleotide of the acceptor splice site in a Sicilian subject.
Genomics 1992;13(1):234-5.
1992: M J McGinniss; Haig Kazazian ; Gail Stetten; Michael B Petersen; H Boman; E Engel; F Greenberg; J M Hertz; A Johnson; Z Laca
Mechanisms of ring chromosome formation in 11 cases of human ring chromosome 21.
American journal of human genetics 1992;50(1):15-28.
1992: Y A Berlin; Haig Kazazian
Rapid preparation of genomic DNA from dried blood and saliva spots for polymerase chain reaction.
Human mutation 1992;1(3):260-1.
1991: S L Mathias; Alan F Scott; Haig Kazazian ; Jef Boeke; A Gabriel
Reverse transcriptase encoded by a human transposable element.
Science (New York, N.Y.) 1991;254(5039):1808-10.
1991: B A Dombroski; S L Mathias; E Nanthakumar; Alan F Scott; Haig Kazazian
Isolation of an active human transposable element.
Science (New York, N.Y.) 1991;254(5039):1805-8.
1991: M J McGinniss; M A Horisberger; Haig Kazazian ; S E Antonarakis
An MspI polymorphism at the MX1 locus in 21q22.3.
Nucleic acids research 1991;19(19):5451.
1991: M Higuchi; S E Antonarakis; L Kasch; J Oldenburg; E Economou-Petersen; K Olek; M Arai; H Inaba; Haig Kazazian
Molecular characterization of mild-to-moderate hemophilia A: detection of the mutation in 25 of 29 patients by denaturing gradient gel electrophoresis.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8307-11.
1991: E P Economou; S E Antonarakis; C C Dowling; Bertha Ibarra; E de la Mora; Haig Kazazian
Molecular heterogeneity of beta-thalassemia in mestizo Mexicans.
Genomics 1991;11(2):474.
1991: Edward G D Tuddenham; David N Cooper; Jane Gitschier; M Higuchi; L W Hoyer; A Yoshioka; I R Peake; Rainer Schwaab; K Olek; Haig Kazazian
Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene.
Nucleic acids research 1991;19(18):4821-33.
1991: Mark I Evans; Anne E Greb; Louis Kunkel; A J Sacks; MP Johnson; Corinne D Boehm; Haig Kazazian ; Eric Hoffman
In utero fetal muscle biopsy for the diagnosis of Duchenne muscular dystrophy.
American journal of obstetrics and gynecology 1991;165(3):728-32.
1991: M Higuchi; Haig Kazazian ; L Kasch; T C Warren; M J McGinniss; J A Phillips; C Kasper; R Janco; S E Antonarakis
Molecular characterization of severe hemophilia A suggests that about half the mutations are not within the coding regions and splice junctions of the factor VIII gene.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7405-9.
1991: Haig Kazazian
Prenatal diagnosis of beta-thalassemia.
Seminars in perinatology 1991;15(3 Suppl 2):15-24.
1991: E H Mules; C E Dowling; M B Petersen; Haig Kazazian ; George H Thomas
A novel mutation in the invariant AG of the acceptor splice site of intron 4 of the beta-hexosaminidase alpha-subunit gene in two unrelated American black GM2-gangliosidosis (Tay-Sachs disease) patients.
American journal of human genetics 1991;48(6):1181-5.
1991: P Woods-Samuels; Haig Kazazian ; S E Antonarakis
Nonhomologous recombination in the human genome: deletions in the human factor VIII gene.
Genomics 1991;10(1):94-101.
1991: K J Hofman; Gary Steel; Haig Kazazian ; David Valle
Phenylketonuria in U.S. blacks: molecular analysis of the phenylalanine hydroxylase gene.
American journal of human genetics 1991;48(4):791-8.
1991: Deborah Rund; T Cohen; Dvora Filon; C E Dowling; T C Warren; I Barak; Eliezer A Rachmilewitz; Haig Kazazian ; Ariella Oppenheim
Evolution of a genetic disease in an ethnic isolate: beta-thalassemia in the Jews of Kurdistan.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(1):310-4.
1991: E P Economou; S E Antonarakis; Haig Kazazian ; G R Serjeant; George J Dover
Variation in hemoglobin F production among normal and sickle cell adults is not related to nucleotide substitutions in the gamma promoter regions.
Blood 1991;77(1):174-7.
1990: Garry R Cutting; L M Kasch; Beryl J Rosenstein; L C Tsui; Haig Kazazian ; S E Antonarakis
Two patients with cystic fibrosis, nonsense mutations in each cystic fibrosis gene, and mild pulmonary disease.
The New England journal of medicine 1990;323(24):1685-9.
1990: Gail Stetten; Cathy M Tuck-Muller; Karin J Blakemore; C Wong; Haig Kazazian ; S E Antonarakis
Evidence for involvement of a Robertsonian translocation 13 chromosome in formation of a ring chromosome 13.
Molecular biology & medicine 1990;7(6):479-84.
1990: Ariella Oppenheim; Arieh Yaari; Deborah Rund; Eliezer A Rachmilewitz; D Nathan; C Wong; Haig Kazazian ; B Miller
Intrinsic potential for high fetal hemoglobin production in a Druz family with beta-thalassemia is due to an unlinked genetic determinant.
Human genetics 1990;86(2):175-80.
1990: Corinne D Boehm; Haig Kazazian
The molecular basis of genetic disease.
Current opinion in biotechnology 1990;1(2):180-7.
1990: P Parikh; M Cotton; Corinne D Boehm; Haig Kazazian
Ethnic distribution of beta-thalassaemia in Indian subcontinent.
Lancet 1990;336(8721):1006.
1990: J G Adams; Martin H Steinberg; Haig Kazazian
Isolation and characterization of the translation product of a beta-globin gene nonsense mutation (beta 121 GAA----TAA).
British journal of haematology 1990;75(4):561-7.
1990: Garry R Cutting; L M Kasch; Beryl J Rosenstein; Julian Zielenski; L C Tsui; S E Antonarakis; Haig Kazazian
A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein.
Nature 1990;346(6282):366-9.
1990: David H K Chui; Margie Patterson; C E Dowling; Haig Kazazian ; A G Kendall
Hemoglobin Bart's disease in an Italian boy. Interaction between alpha-thalassemia and hereditary persistence of fetal hemoglobin.
The New England journal of medicine 1990;323(3):179-82.
1990: Haig Kazazian
The thalassemia syndromes: molecular basis and prenatal diagnosis in 1990.
Seminars in hematology 1990;27(3):209-28.
1990: M D Traystman; M Higuchi; C K Kasper; S E Antonarakis; Haig Kazazian
Use of denaturing gradient gel electrophoresis to detect point mutations in the factor VIII gene.
Genomics 1990;6(2):293-301.
1990: M Arai; M Higuchi; S E Antonarakis; Haig Kazazian ; J A Phillips; R L Janco; Leon Hoyer
Characterization of a thrombin cleavage site mutation (Arg 1689 to Cys) in the factor VIII gene of two unrelated patients with cross-reacting material-positive hemophilia A.
Blood 1990;75(2):384-9.
1990: S E Antonarakis; Haig Kazazian
The molecular basis of hemophilia A (factor VIII deficiency) in man; progress report from the Johns Hopkins University Hemophilia Project.
Progress in clinical and biological research 1990;324():1-11.
1990: VIRGINIA CORSON; K Quaid; L Kasch; Haig Kazazian
Prenatal testing for Huntington disease.
Birth defects original article series 1990;26(3):226-30.
1990: M Higuchi; C Wong; L Kochhan; K Olek; S Aronis; C K Kasper; Haig Kazazian ; S E Antonarakis
Characterization of mutations in the factor VIII gene by direct sequencing of amplified genomic DNA.
Genomics 1990;6(1):65-71.
1990: Haig Kazazian
Current status of prenatal diagnosis by DNA analysis.
Birth defects original article series 1990;26(3):210-6.
1990: J C Long; Aravinda Chakravarti; Corinne D Boehm; S Antonarakis; Haig Kazazian
Phylogeny of human beta-globin haplotypes and its implications for recent human evolution.
American journal of physical anthropology 1990;81(1):113-30.
1990: Deborah Rund; Dvora Filon; C Dowling; Haig Kazazian ; Eliezer A Rachmilewitz; Ariella Oppenheim
Molecular studies of beta-thalassemia in Israel. Mutational analysis and expression studies.
Annals of the New York Academy of Sciences 1990;612():98-105.
1990: Haig Kazazian ; C E Dowling; Corinne D Boehm; T C Warren; E P Economou; J Katz; S E Antonarakis
Gene defects in beta-thalassemia and their prenatal diagnosis.
Annals of the New York Academy of Sciences 1990;612():1-14.
1990: H Inaba; M Fujimaki; Haig Kazazian ; S E Antonarakis
MspI polymorphic site in intron 22 of the factor VIII gene in the Japanese population.
Human genetics 1990;84(2):214-5.
1989: X F Cui; Hong Hua Li; T M Goradia; K Lange; Haig Kazazian ; D Galas; Norman Arnheim
Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9389-93.
1989: Haig Kazazian
Diagnosis by gene amplification.
The Journal of laboratory and clinical medicine 1989;114(2):95-6.
1989: R M Zweig; S J Koven; J C Hedreen; NE Maestri; Haig Kazazian ; Susan E Folstein
Linkage to the Huntington's disease locus in a family with unusual clinical and pathological features.
Annals of neurology 1989;26(1):78-84.
1989: Jason Brandt; K A Quaid; Susan E Folstein; P Garber; NE Maestri; Margaret H Abbott; Phillip R Slavney; ML Franz; L Kasch; Haig Kazazian
Presymptomatic diagnosis of delayed-onset disease with linked DNA markers. The experience in Huntington's disease.
JAMA : the journal of the American Medical Association 1989;261(21):3108-14.
1989: M Arai; H Inaba; M Higuchi; S E Antonarakis; Haig Kazazian ; M Fujimaki; Leon Hoyer
Direct characterization of factor VIII in plasma: detection of a mutation altering a thrombin cleavage site (arginine-372----histidine).
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4277-81.
1989: P Woods-Samuels; C Wong; S L Mathias; Alan F Scott; Haig Kazazian ; S E Antonarakis
Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements.
Genomics 1989;4(3):290-6.
1989: Gregg L Semenza; C E Dowling; Haig Kazazian
Hinf I polymorphism 3' to the human beta-globin gene detected by the polymerase chain reaction (PCR).
Nucleic acids research 1989;17(6):2376.
1989: C Wong; S E Antonarakis; S C Goff; Stuart H Orkin; B G Forget; David G Nathan; Patricia J Giardina; Haig Kazazian
Beta-thalassemia due to two novel nucleotide substitutions in consensus acceptor splice sequences of the beta-globin gene.
Blood 1989;73(4):914-8.
1989: C Wong; Haig Kazazian ; Gail Stetten; William C Earnshaw; M L Van Keuren; S E Antonarakis
Molecular mechanism in the formation of a human ring chromosome 21.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(6):1914-8.
1989: Garry R Cutting; S E Antonarakis; K H Buetow; L M Kasch; Beryl J Rosenstein; Haig Kazazian
Analysis of DNA polymorphism haplotypes linked to the cystic fibrosis locus in North American black and Caucasian families supports the existence of multiple mutations of the cystic fibrosis gene.
American journal of human genetics 1989;44(3):307-18.
1989: H Inaba; M Fujimaki; Haig Kazazian ; S E Antonarakis
Mild hemophilia A resulting from Arg-to-Leu substitution in exon 26 of the factor VIII gene.
Human genetics 1989;81(4):335-8.
1989: Haig Kazazian ; D G Phillips; C E Dowling; Corinne D Boehm
Prenatal diagnosis of sickle cell anemia--1988.
Annals of the New York Academy of Sciences 1989;565():44-7.
1989: Surinder Safaya; R F Rieder; C E Dowling; Haig Kazazian ; J G Adams
Homozygous beta-thalassemia without anemia.
Blood 1989;73(1):324-8.
1988: R Di Marzo; Aurelio Maggio; S D'Agostino; C E Dowling; C Wong; Haig Kazazian
A rapid DNA method for first-trimester prenatal diagnosis.
British journal of haematology 1988;70(4):504-5.
1988: Garry R Cutting; S E Antonarakis; H Youssoufian; Haig Kazazian
Accuracy and limitations of pulsed field gel electrophoresis in sizing partial deletions of the factor VIII gene.
Molecular biology & medicine 1988;5(3):173-84.
1988: Garry R Cutting; Haig Kazazian ; S E Antonarakis; Paul D Killen; Y Yamada; Clair A Francomano
Macrorestriction mapping of COL4A1 and COL4A2 collagen genes on human chromosome 13q34.
Genomics 1988;3(3):256-63.
1988: H Youssoufian; C K Kasper; D G Phillips; Haig Kazazian ; S E Antonarakis
Restriction endonuclease mapping of six novel deletions of the factor VIII gene in hemophilia A.
Human genetics 1988;80(2):143-8.
1988: Haig Kazazian ; Corinne D Boehm
Molecular basis and prenatal diagnosis of beta-thalassemia.
Blood 1988;72(4):1107-16.
1988: Randall K Saiki; C A Chang; C H Levenson; T C Warren; Corinne D Boehm; Haig Kazazian ; Henry A Erlich
Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes.
The New England journal of medicine 1988;319(9):537-41.
1988: George F Atweh; H E Brickner; XX Zhu; Haig Kazazian ; B G Forget
New amber mutation in a beta-thalassemic gene with nonmeasurable levels of mutant messenger RNA in vivo.
The Journal of clinical investigation 1988;82(2):557-61.
1988: S E Antonarakis; Haig Kazazian
The molecular basis of hemophilia A in man.
Trends in genetics : TIG 1988;4(8):233-7.
1988: R Anand; Corinne D Boehm; Haig Kazazian ; E F Vanin
Molecular characterization of a beta zero-thalassemia resulting from a 1.4 kilobase deletion.
Blood 1988;72(2):636-41.
1988: R Di Marzo; C E Dowling; C Wong; Aurelio Maggio; Haig Kazazian
The spectrum of beta-thalassaemia mutations in Sicily.
British journal of haematology 1988;69(3):393-7.
1988: H Youssoufian; C Wong; S Aronis; H Platokoukis; Haig Kazazian ; S E Antonarakis
Moderately severe hemophilia A resulting from Glu----Gly substitution in exon 7 of the factor VIII gene.
American journal of human genetics 1988;42(6):867-71.
1988: H Youssoufian; S E Antonarakis; W Bell; A M Griffin; Haig Kazazian
Nonsense and missense mutations in hemophilia A: estimate of the relative mutation rate at CG dinucleotides.
American journal of human genetics 1988;42(5):718-25.
1988: Haig Kazazian ; C Wong; H Youssoufian; Alan F Scott; D G Phillips; S E Antonarakis
Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.
Nature 1988;332(6160):164-6.
1988: Haig Kazazian ; S E Antonarakis
The varieties of mutation.
Progress in medical genetics 1988;7():43-67.
1988: S Huang; P G Waber; C E Dowling; C Wong; S E Antonarakis; R L Cai; M Q Wang; W H Lo; Haig Kazazian
Beta-thalassemia in China: a systematic molecular characterization of beta-thalassemia mutations.
Hemoglobin 1988;12(5-6):621-8.
1988: H Youssoufian; Haig Kazazian ; A Patel; S Aronis; G Tsiftis; L W Hoyer; S E Antonarakis
Mild hemophilia A associated with a cryptic donor splice site mutation in intron 4 of the factor VIII gene.
Genomics 1988;2(1):32-6.
1987: C Wong; C E Dowling; Randall K Saiki; R G Higuchi; Henry A Erlich; Haig Kazazian
Characterization of beta-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA.
Nature 1987;330(6146):384-6.
1987: George F Atweh; XX Zhu; H E Brickner; C H Dowling; Haig Kazazian ; B G Forget
The beta-globin gene on the Chinese delta beta-thalassemia chromosome carries a promoter mutation.
Blood 1987;70(5):1470-4.
1987: S Kittur; M L Lubs; M Bauer; Aravinda Chakravarti; Haig Kazazian
Linkage analysis of neurofibromatosis.
Journal of medical genetics 1987;24(9):526-7.
1987: H Youssoufian; D G Phillips; Haig Kazazian ; S E Antonarakis
MspI polymorphism in the 3' flanking region of the human factor VIII gene.
Nucleic acids research 1987;15(15):6312.
1987: G F Atweh; C Wong; R Reed; S E Antonarakis; D Zhu; P K Ghosh; T Maniatis; B G Forget; Haig Kazazian
A new mutation in IVS-1 of the human beta globin gene causing beta thalassemia due to abnormal splicing.
Blood 1987;70(1):147-51.
1987: H Youssoufian; S E Antonarakis; S Aronis; G Tsiftis; D G Phillips; Haig Kazazian
Characterization of five partial deletions of the factor VIII gene.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3772-6.
1987: S E Antonarakis; H Youssoufian; Haig Kazazian
Molecular genetics of hemophilia A in man (factor VIII deficiency).
Molecular biology & medicine 1987;4(2):81-94.
1987: Haig Kazazian ; C Junien
Report of the committee on the genetic constitution of chromosomes 10, 11, and 12.
Cytogenetics and cell genetics 1987;46(1-4):188-212.
1987: Haig Kazazian ; C E Dowling; P G Waber; S Z Huang; W H Lo; A Li; J W Tam; J Kang; S E Antonarakis
Molecular characterization of beta-thalassemia major and beta-thalassemia intermedia in China and Southeast Asia.
Progress in clinical and biological research 1987;251():401-12.
1987: Deborah A Meyers; Terri H beaty; N E Maestri; S D Kittur; S E Antonarakis; Haig Kazazian
Multipoint mapping studies of six loci on chromosome 11.
Human heredity 1987;37(2):94-101.
1987: Haig Kazazian
Globin gene structure and the nature of mutation.
Birth defects original article series 1987;23(3):77-92.
1986: H Youssoufian; Haig Kazazian ; D G Phillips; S Aronis; G Tsiftis; V A Brown; S E Antonarakis
Recurrent mutations in haemophilia A give evidence for CpG mutation hotspots.
Nature 1986;324(6095):380-2.
1986: Deborah A Meyers; Terri H beaty; N E Maestri; S E Antonarakis; Haig Kazazian
Multipoint mapping studies of the beta-globin, insulin, and c-Ha-ras-1 loci on 11p.
American journal of human genetics 1986;39(4):539-41.
1986: S Huang; C Wong; S E Antonarakis; T Ro-lien; W H Lo; Haig Kazazian
The same "TATA" box beta-thalassemia mutation in Chinese and US blacks: another example of independent origins of mutation.
Human genetics 1986;74(2):162-4.
1986: Haig Kazazian ; C E Dowling; P G Waber; S Huang; W H Lo
The spectrum of beta-thalassemia genes in China and Southeast Asia.
Blood 1986;68(4):964-6.
1986: C Wong; S E Antonarakis; S C Goff; Stuart H Orkin; Corinne D Boehm; Haig Kazazian
On the origin and spread of beta-thalassemia: recurrent observation of four mutations in different ethnic groups.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6529-32.
1986: Haig Kazazian ; Stuart H Orkin; Corinne D Boehm; S C Goff; C Wong; C E Dowling; P E Newburger; R G Knowlton; V Brown; H Donis-Keller
Characterization of a spontaneous mutation to a beta-thalassemia allele.
American journal of human genetics 1986;38(6):860-7.
1986: R Gelinas; M Bender; C Lotshaw; P Waber; Haig Kazazian ; G Stamatoyannopoulos
Chinese A gamma fetal hemoglobin: C to T substitution at position-196 of the A gamma gene promoter.
Blood 1986;67(6):1777-9.
1986: Aravinda Chakravarti; K H Buetow; S E Antonarakis; P G Waber; Corinne D Boehm; Haig Kazazian
Nonuniform recombination within the human beta-globin gene cluster: A reply to B. S. Weir and W. G. Hill.
American journal of human genetics 1986;38(5):779-81.
1986: Corinne D Boehm; C E Dowling; P G Waber; Patricia J Giardina; Haig Kazazian
Use of oligonucleotide hybridization in the characterization of a beta zero-thalassemia gene (beta 37 TGG----TGA) in a Saudi Arabian family.
Blood 1986;67(4):1185-8.
1986: T Cohen; S K Karathanasis; Haig Kazazian ; S E Antonarakis
DNA polymorphic sites in the human ApoAI-CIII-AIV cluster: Taq I and Ava I.
Nucleic acids research 1986;14(4):1924.
1986: P G Waber; MA Bender; R E Gelinas; C Kattamis; A Karaklis; K Sofroniadou; George Stamatoyannopoulos; Francis S Collins; B G Forget; Haig Kazazian
Concordance of a point mutation 5' to the A gamma-globin gene with A gamma beta + hereditary persistence of fetal hemoglobin in Greeks.
Blood 1986;67(2):551-4.
1986: Haig Kazazian
The William Allan Memorial Award presented to Yuet Wai Kan.
American journal of human genetics 1986;38(1):1-3.
1986: Deborah A Meyers; Terri H beaty; S E Antonarakis; Haig Kazazian ; Raymond White
Genetic analysis workshop IV: the 11p data sets.
Genetic epidemiology. Supplement 1986;1():95-7.
1986: Haig Kazazian ; S E Antonarakis; H Youssoufian; C E Dowling; D G Phillips; C Wong; Corinne D Boehm
Comparison of deficiency alleles of the beta-globin and factor VIII:C genes: new lessons from a giant gene.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 1():371-9.
1986: Clair A Francomano; Haig Kazazian
DNA analysis in genetic disorders.
Annual review of medicine 1986;37():377-95.
1985: S Z Huang; Haig Kazazian ; P G Waber; H Y Luo; R L Cai; M Q Wang
Beta-thalassemia in Chinese--analysis of polymorphic restriction site haplotypes in the beta-globin gene cluster.
Chinese medical journal 1985;98(12):881-6.
1985: S E Antonarakis; P G Waber; S D Kittur; A S Patel; Haig Kazazian ; M A Mellis; R B Counts; G Stamatoyannopoulos; E J Bowie; D N Fass
Hemophilia A. Detection of molecular defects and of carriers by DNA analysis.
The New England journal of medicine 1985;313(14):842-8.
1985: S D Kittur; S E Antonarakis; Rudolph E Tanzi; Deborah A Meyers; Aravinda Chakravarti; Y Groner; J A Phillips; P C Watkins; James Gusella; Haig Kazazian
A linkage map of three anonymous human DNA fragments and SOD-1 on chromosome 21.
The EMBO journal 1985;4(9):2257-60.
1985: Haig Kazazian
Gene probes: application to prenatal and postnatal diagnosis of genetic disease.
Clinical chemistry 1985;31(9):1509-13.
1985: Susan E Folstein; J A Phillips; Deborah A Meyers; G A Chase; Margaret H Abbott; ML Franz; P G Waber; Haig Kazazian ; P M Conneally; W Hobbs
Huntington's disease: two families with differing clinical features show linkage to the G8 probe.
Science (New York, N.Y.) 1985;229(4715):776-9.
1985: S D Kittur; J W Hoppener; S E Antonarakis; J D Daniels; Deborah A Meyers; N E Maestri; M Jansen; R G Korneluk; Barry D Nelkin; Haig Kazazian
Linkage map of the short arm of human chromosome 11: location of the genes for catalase, calcitonin, and insulin-like growth factor II.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(15):5064-7.
1985: Corinne D Boehm; C E Dowling; S E Antonarakis; George R Honig; Haig Kazazian
Evidence supporting a single origin of the beta(C)-globin gene in blacks.
American journal of human genetics 1985;37(4):771-7.
1985: S E Antonarakis; K L Copeland; R J Carpenter; C A Carta; Leon Hoyer; C T Caskey; J J Toole; Haig Kazazian
Prenatal diagnosis of haemophilia A by factor VIII gene analysis.
Lancet 1985;1(8443):1407-9.
1985: Haig Kazazian
The nature of mutation.
Hospital practice (Office ed.) 1985;20(2):55-65, 69.
1985: Stuart H Orkin; T C Cheng; S E Antonarakis; Haig Kazazian
Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene.
The EMBO journal 1985;4(2):453-6.
1985: S E Antonarakis; Haig Kazazian ; Stuart H Orkin
DNA polymorphism and molecular pathology of the human globin gene clusters.
Human genetics 1985;69(1):1-14.
1985: K H Grzeschik; Haig Kazazian
Report of the Committee on the Genetic Constitution of Chromosomes 10, 11, and 12.
Cytogenetics and cell genetics 1985;40(1-4):179-205.
1985: Haig Kazazian ; S E Antonarakis; C Wong; S P Trusko; Gail Stetten; M Oliver; M J Potter; James Gusella; P C Watkins
Ring chromosome 21: characterization of DNA sequences at sites of breakage and reunion.
Annals of the New York Academy of Sciences 1985;450():33-42.
1985: Corinne D Boehm; Haig Kazazian
Prenatal diagnosis of hemoglobinopathies by DNA analysis.
Critical reviews in oncology/hematology 1985;4(2):155-67.
1985: Haig Kazazian ; Corinne D Boehm; C E Dowling
Prenatal diagnosis of hemoglobinopathies by DNA analysis.
Annals of the New York Academy of Sciences 1985;445():337-48.
1985: R Gelinas; M Yagi; B Endlich; C Lotshaw; Haig Kazazian ; G Stamatoyannopoulos
Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene.
Progress in clinical and biological research 1985;191():125-39.
1984: Francis S Collins; Corinne D Boehm; P G Waber; C J Stoeckert; S M Weissman; B G Forget; Haig Kazazian
Concordance of a point mutation 5' to the G gamma globin gene with G gamma beta +. Hereditary persistence of fetal hemoglobin in the black population.
Blood 1984;64(6):1292-6.
1984: Aravinda Chakravarti; K H Buetow; S E Antonarakis; P G Waber; Corinne D Boehm; Haig Kazazian
Nonuniform recombination within the human beta-globin gene cluster.
American journal of human genetics 1984;36(6):1239-58.
1984: Stuart H Orkin; S E Antonarakis; Haig Kazazian
Base substitution at position -88 in a beta-thalassemic globin gene. Further evidence for the role of distal promoter element ACACCC.
The Journal of biological chemistry 1984;259(14):8679-81.
1984: Haig Kazazian ; Stuart H Orkin; A F Markham; C R Chapman; H Youssoufian; P G Waber
Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans.
Nature 1984;310(5973):152-4.
1984: Corinne D Boehm; Haig Kazazian
Error in prenatal diagnosis by DNA analysis.
The New England journal of medicine 1984;311(1):58.
1984: Rona S Weinberg; S E Antonarakis; Haig Kazazian ; George J Dover; Stuart H Orkin; A L Lenes; J M Schofield; BLANCHE ALTER
Fetal hemoglobin synthesis in erythroid cultures in hereditary persistence of fetal hemoglobin and beta o-thalassemia.
Blood 1984;63(6):1278-84.
1984: T C Cheng; Stuart H Orkin; S E Antonarakis; M J Potter; J P Sexton; A F Markham; Patricia J Giardina; A Li; Haig Kazazian
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(9):2821-5.
1984: Haig Kazazian ; Stuart H Orkin; S E Antonarakis; J P Sexton; Corinne D Boehm; S C Goff; P G Waber
Molecular characterization of seven beta-thalassemia mutations in Asian Indians.
The EMBO journal 1984;3(3):593-6.
1984: S E Antonarakis; S H Irkin; T C Cheng; Alan F Scott; J P Sexton; Stephen P Trusko; S Charache; Haig Kazazian
beta-Thalassemia in American Blacks: novel mutations in the "TATA" box and an acceptor splice site.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(4):1154-8.
1984: S E Antonarakis; Corinne D Boehm; G R Serjeant; C E Theisen; George J Dover; Haig Kazazian
Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(3):853-6.
1984: M H Hutz; A M Michelson; S E Antonarakis; Stuart H Orkin; Haig Kazazian
Restriction site polymorphism in the phosphoglycerate kinase gene on the X chromosome.
Human genetics 1984;66(2-3):217-9.
1984: Haig Kazazian ; P G Waber; Corinne D Boehm; J I Lee; S E Antonarakis; V F Fairbanks
Hemoglobin E in Europeans: further evidence for multiple origins of the beta E-globin gene.
American journal of human genetics 1984;36(1):212-7.
1984: Stuart H Orkin; Haig Kazazian
The mutation and polymorphism of the human beta-globin gene and its surrounding DNA.
Annual review of genetics 1984;18():131-71.
1983: S E Antonarakis; J A Phillips; R L Mallonee; Haig Kazazian ; Eric R Fearon; P G Waber; H M Kronenberg; A Ullrich; Deborah A Meyers
Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(21):6615-9.
1983: Haig Kazazian ; Stuart H Orkin; Corinne D Boehm; J P Sexton; S E Antonarakis
beta-Thalassemia due to a deletion of the nucleotide which is substituted in the beta S-globin gene.
American journal of human genetics 1983;35(5):1028-33.
1983: Stuart H Orkin; J P Sexton; T C Cheng; S C Goff; Patricia J Giardina; J I Lee; Haig Kazazian
ATA box transcription mutation in beta-thalassemia.
Nucleic acids research 1983;11(14):4727-34.
1983: Corinne D Boehm; Haig Kazazian
Prenatal diagnosis of hemoglobinopathies--1983.
Seminars in perinatology 1983;7(3):175-83.
1983: Stuart H Orkin; J P Sexton; S C Goff; Haig Kazazian
Inactivation of an acceptor RNA splice site by a short deletion in beta-thalassemia.
The Journal of biological chemistry 1983;258(12):7249-51.
1983: Eric R Fearon; Haig Kazazian ; P G Waber; J I Lee; S E Antonarakis; Stuart H Orkin; E F Vanin; P S Henthorn; Frank Grosveld; Alan F Scott; G R Buchanan
The entire beta-globin gene cluster is deleted in a form of gamma delta beta-thalassemia.
Blood 1983;61(6):1269-74.
1983: Corinne D Boehm; S E Antonarakis; J A Phillips; Gail Stetten; Haig Kazazian
Prenatal diagnosis using DNA polymorphisms. Report on 95 pregnancies at risk for sickle-cell disease or beta-thalassemia.
The New England journal of medicine 1983;308(18):1054-8.
1983: Stuart H Orkin; A F Markham; Haig Kazazian
Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis.
The Journal of clinical investigation 1983;71(3):775-9.
1983: Haig Kazazian ; S E Antonarakis; T Cheng; Corinne D Boehm; P G Waber
Use of haplotype analysis in the beta-globin gene cluster to discover beta-thalassemia mutations.
Progress in clinical and biological research 1983;134():91-8.
1983: Haig Kazazian
Gene structure and the nature of mutation.
Mead Johnson Symposium on Perinatal and Developmental Medicine 1983;(22):3-11.
1983: Stuart H Orkin; S E Antonarakis; Haig Kazazian
Polymorphism and molecular pathology of the human beta-globin gene.
Progress in hematology 1983;13():49-73.
1982: Stuart H Orkin; Haig Kazazian ; S E Antonarakis; Harry Ostrer; S C Goff; J P Sexton
Abnormal RNA processing due to the exon mutation of beta E-globin gene.
Nature 1982;300(5894):768-9.
1982: S E Antonarakis; Stuart H Orkin; Haig Kazazian ; S C Goff; Corinne D Boehm; P G Waber; J P Sexton; Harry Ostrer; V F Fairbanks; Aravinda Chakravarti
Evidence for multiple origins of the beta E-globin gene in Southeast Asia.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(21):6608-11.
1982: Stuart H Orkin; P F Little; Haig Kazazian ; Corinne D Boehm
Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis.
The New England journal of medicine 1982;307(1):32-6.
1982: S E Antonarakis; J A Phillips; Haig Kazazian
Genetic diseases: diagnosis by restriction endonuclease analysis.
The Journal of pediatrics 1982;100(6):845-56.
1982: Stuart H Orkin; Haig Kazazian ; S E Antonarakis; S C Goff; Corinne D Boehm; J P Sexton; P G Waber; Patricia J Giardina
Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.
Nature 1982;296(5858):627-31.
1982: G G Johnson; A L Ramage; J W Littlefield; Haig Kazazian
Hypoxanthine-guanine phosphoribosyltransferase in human erythroid cells: posttranslational modification.
Biochemistry 1982;21(5):960-6.
1982: George H Thomas; S Raghavan; E H Kolodny; A Frisch; E F Neufeld; J S O'Brien; L W Reynolds; C S Miller; J Shapiro; Haig Kazazian ; R H Heller
Nonuniform deficiency of hexosaminidase A in tissues and fluids of two unrelated individuals.
Pediatric research 1982;16(3):232-7.
1982: L Cavalli-Sforza; K Davies; Kirby D Smith; P Pearson; P Gerald; S Naylor; Haig Kazazian ; R White; R Elliot; L Crippa; B Young; M Skolnick; M Nei
Workshop on DNA polymorphisms.
Progress in clinical and biological research 1982;103 Pt A():79-81.
1982: Corinne D Boehm; J A Phillips; S Antonarakis; Haig Kazazian
Prenatal diagnosis by restriction analysis: methodology and experience.
Progress in clinical and biological research 1982;98():17-26.
1982: S E Antonarakis; Corinne D Boehm; Patricia J Giardina; Haig Kazazian
Nonrandom association of polymorphic restriction sites in the beta-globin gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(1):137-41.
1981: Alan F Scott; J A Phillips; K E Young; Haig Kazazian ; Kirby D Smith; S Charache; J B Clegg
The molecular basis of hemoglobin Grady.
American journal of human genetics 1981;33(1):129-33.
1981: SUSAN PANNY; Alan F Scott; Kirby D Smith; J A Phillips; Haig Kazazian ; C Conover Talbot; Corinne D Boehm
Population heterogeneity of the Hpa I restriction site associated with the beta globin gene: implications for prenatal diagnosis.
American journal of human genetics 1981;33(1):25-35.
1980: Haig Kazazian ; J A Phillips; Corinne D Boehm; T A Vik; M J Mahoney; A K Ritchey
Prenatal diagnosis of beta-thalassemias by amniocentesis: linkage analysis using multiple polymorphic restriction endonuclease sites.
Blood 1980;56(5):926-30.
1980: J A Phillips; T A Vik; Alan F Scott; K E Young; Haig Kazazian ; Kirby D Smith; V F Fairbanks; H M Koenig
Unequal crossing-over: a common basis of single alpha-globin genes in Asians and American blacks with hemoglobin-H disease.
Blood 1980;55(6):1066-9.
1980: J A Phillips; SUSAN PANNY; Haig Kazazian ; Corinne D Boehm; Alan F Scott; Kirby D Smith
Prenatal diagnosis of sickle cell anemia by restriction and endonuclease analysis: HindIII polymorphisms in gamma-globin genes extend test applicability.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2853-6.
1979: J A Phillips; Alan F Scott; Kirby D Smith; K E Young; K L Lightbody; R M Jiji; Haig Kazazian
A molecular basis for hemoglobin-H disease in American blacks.
Blood 1979;54(6):1439-45.
1979: J A Phillips; Alan F Scott; Haig Kazazian ; Kirby D Smith; Gail Stetten; George H Thomas
Prenatal diagnosis of hemoglobinopathies by restriction endonuclease analysis: pregnancies at risk for sickle cell anemia and S--O Arab disease.
The Johns Hopkins medical journal 1979;145(2):57-60.
1979: J M Swint; J M Shapiro; VIRGINIA CORSON; L W Reynolds; George H Thomas; Haig Kazazian
The economic returns to community and hospital screening programs for a genetic disease.
Preventive medicine 1979;8(4):463-70.
1979: S Charache; STEPHEN ACHUFF; R Winslow; Haig Kazazian
Oxygen transport in a woman with hemoglobin Hope/beta+ thalassemia.
The Journal of laboratory and clinical medicine 1979;93(2):316-20.
1979: J A Phillips; D M Sedlak; T C Cheng; Haig Kazazian
Ratios of alpha- to beta-globin RNA sequences in the erythropoietic mouse spleen.
FEBS letters 1979;97(2):327-9.
1978: Haig Kazazian ; G L Dover; K L Lightbody; I J Park
Prenatal diagnosis in a fetus at risk for hemoglobin S-O Arab disease.
The Journal of pediatrics 1978;93(3):502-4.
1978: S Cho; T Cheng; Haig Kazazian
Characterization of 5'-terminal methylation of human alpha- and beta-globin mRNAs.
The Journal of biological chemistry 1978;253(16):5558-61.
1978: C O Leonard; Haig Kazazian
Prenatal diagnosis of hemoglobinopathies.
Pediatric clinics of North America 1978;25(3):631-42.
1978: VIRGINIA CORSON; Haig Kazazian
Unadjusted carrier frequency for community screening programs.
American journal of human genetics 1978;30(2):227.
1978: T Cheng; Haig Kazazian
Sequential methylation of globin mRNA in nucleated erythroid cells and reticulocytes of mice.
The Journal of biological chemistry 1978;253(1):246-51.
1977: J A Phillips; P G Snyder; Haig Kazazian
Ratios of alpha-to beta-globin mRNA and regulation of globin synthesis in reticulocytes.
Nature 1977;269(5627):442-5.
1977: S Charache; J Fox; P McCurdy; Haig Kazazian ; R Winslow; P Hathaway; R van Beneden; M Jessop
Postsynthetic deamidation of hemoglobin Providence (beta 82 Lys replaced by Asn, Asp) and its effect on oxygen transport.
The Journal of clinical investigation 1977;59(4):652-8.
1977: T C Cheng; Haig Kazazian
The 5'-terminal structures of murine alpha- and beta-globin messenger RNA.
The Journal of biological chemistry 1977;252(5):1758-63.
1977: George J Dover; S H Boyer; W H Zinkham; Haig Kazazian ; D J Pinney; A Sigler
Changing erythrocyte populations in juvenile chronic myelocytic leukemia: evidence for disordered regulation.
Blood 1977;49(3):355-65.
1977: Haig Kazazian ; S Cho; J A Phillips
The mutational basis of the thalassemia syndromes.
Progress in medical genetics 1977;2():165-204.
1976: Barton Childs; LEON GORDIS; M M Kaback; Haig Kazazian
Tay-Sachs screening: social and psychological impact.
American journal of human genetics 1976;28(6):550-8.
1976: Barton Childs; LEON GORDIS; M M Kaback; Haig Kazazian
Tay-Sachs screening: motives for participating and knowledge of genetics and probability.
American journal of human genetics 1976;28(6):537-49.
1976: H W Dickerman; T C Cheng; Haig Kazazian ; Jerry L Spivak
The erythropoietic mouse spleen-a model system of development.
Archives of biochemistry and biophysics 1976;177(1):1-9.
1976: Haig Kazazian
The hereditary persistence of fetal hemoglobin syndromes: variations on the thalassemia theme.
The Johns Hopkins medical journal 1976;139(5):215-9.
1976: Haig Kazazian ; R J Van Beneden; P G Snyder
beta-thalassemia: studies of the molecular defect in the "D" family.
The Johns Hopkins medical journal 1976;139(5):211-4.
1976: T C Cheng; Haig Kazazian
Unequal accumulation of alpha- and beta-globin mRNA in erythropoietic mouse spleen.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(6):1811-5.
1976: Haig Kazazian ; A M Silverstein; P G Snyder; R J VanBeneden
Increasing haemoglobin beta-chain syntheses in foetal development is associated with a declining gamma-to alpha-mRNA ratio.
Nature 1976;260(5546):67-70.
1976: Haig Kazazian
A geneticist's view of lung disease.
The American review of respiratory disease 1976;113(3):261-6.
1975: Y W Kan; J P Holland; A M Dozy; S Charache; Haig Kazazian
Deletion of the beta-globin structure gene in hereditary persistence of foetal haemoglobin.
Nature 1975;258(5531):162-3.
1975: F H Reynolds; PAULA PITHA-ROWE; R Chuang; T C Cheng; Haig Kazazian ; D Grunberger
Effects of poly(9-vinyladenine) and poly(1-vinyluracil) on messenger ribonucleic acid template activity.
Molecular pharmacology 1975;11(6):708-15.
1975: W E Bucknall; Haig Kazazian ; L T Clement; Barton Childs
Electrophoretic study of human ribosomal core proteins: evidence for selection against variation.
The Johns Hopkins medical journal 1975;137(3):123-6.
1975: Haig Kazazian
Editorial: Prenatal diagnosis of hemoglobinopathies.
The New England journal of medicine 1975;292(21):1125-6.
1975: Haig Kazazian ; G D Ginder; P G Snyder; R J Van Beneden; A P Woodhead
Further evidence of a quantitative deficiency of chain-specific globin mRNA in the thalassemia syndromes.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(2):567-71.
1974: Haig Kazazian ; A P Woodhead
Adult hemoglobin synthesis in the human fetus.
Annals of the New York Academy of Sciences 1974;241(0):691-8.
1974: Haig Kazazian ; T cheng; S K Polmar; G D Ginder
Globin mRNA of mouse spleen erythroblasts.
Annals of the New York Academy of Sciences 1974;241(0):170-82.
1974: Haig Kazazian
Regulation of fetal hemoglobin production.
Seminars in hematology 1974;11(4):525-48.
1974: Haig Kazazian ; P G Snyder; T C Cheng
Separation of alpha- and beta-globin messenger RNAs by formamide gel electrophoresis.
Biochemical and biophysical research communications 1974;59(3):1053-61.
1974: T Cheng; S K Polmar; Haig Kazazian
Isolation and characterization of modified globin messenger ribonucleic acid from erythropoietic mouse spleen.
The Journal of biological chemistry 1974;249(6):1781-6.
1973: Haig Kazazian ; A P Woodhead
Hemoglobin A synthesis in the developing fetus.
The New England journal of medicine 1973;289(2):58-62.
1973: Haig Kazazian ; P A Moore; P G Snyder
Identification of globin mRNA in 10s RNA of rabbit reticulocytes.
Biochemical and biophysical research communications 1973;51(3):564-71.
1972: Haig Kazazian
Separation of alpha- and beta-globin messenger RNAs.
Nature: New biology 1972;238(84):166-9.
1972: Haig Kazazian
Antenatal detection of sickle-cell anemia.
The New England journal of medicine 1972;287(1):41-2.
1972: Haig Kazazian ; M M Kaback; A P Woodhead; C O Leonard; W S Nersesian
Further studies on the antenatal detection of sickle cell anemia and other hemoglobinopathies.
Advances in experimental medicine and biology 1972;28():337-46.
1971: M D Hollenberg; M M Kaback; Haig Kazazian
Adult hemoglobin synthesis by reticulocytes from the human fetus at midtrimester.
Science (New York, N.Y.) 1971;174(4010):698-702.
1971: M A Del Monte; Haig Kazazian
Unequal synthesis of globin chains after extended incubation of rabbit reticulocytes with L-O-methylthreonine.
Journal of molecular biology 1971;56(2):429-34.
1968: Haig Kazazian ; M L Freedman
The characterization of separated alpha and beta-chain polyribosomes in rabbit reticulocytes.
The Journal of biological chemistry 1968;243(24):6446-50.
1968: Haig Kazazian ; H A Itano
Studies on the quantitative control of polypeptide synthesis in human reticulocytes.
The Journal of biological chemistry 1968;243(8):2048-55.
1966: Haig Kazazian
Molecular size studies on 6-phosphogluconate dehydrogenase.
Nature 1966;212(5058):197-8.
1965: Haig Kazazian ; W J Young; Barton Childs
X-linked 6-phosphogluconate dehydrogenase in drosophila: subunit associations.
Science (New York, N.Y.) 1965;150(3703):1601-2.