FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Amparo Alfonso

Research Profile

Chemicals & Drugs

Anatomy

Physiology

Concepts & Ideas

Hydrogen-Ion Concentration

Living Beings

Procedures

High Pressure Liquid Chromatography

Co-author Network

Publications

TOP 3
Araceli Tobío; Andrea Fernández-Araujo; Amparo Alfonso; Luis Botana
Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by anchor kinase A mitochondrial proteins.
Paz Otero; Paula Rodríguez; Juan A Rubiolo; Mercedes R Vieytes; Amparo Alfonso; Roberto Bermúdez; José Manuel Cifuentes; Luis Botana
Pharmacokinetic and toxicological data of spirolides after oral and intraperitoneal administration.
M Carmen Louzao; Isabel R Ares; Eva Cagide; Begoña Espiña; Natalia Vilariño; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Palytoxins and cytoskeleton: An overview.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Amparo Alfonso (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Araceli Tobío; Andrea Fernández-Araujo; Amparo Alfonso; Luis Botana
Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by anchor kinase A mitochondrial proteins.
Journal of cellular biochemistry 2012;113(12):3752-61.
2012: Paz Otero; Paula Rodríguez; Juan A Rubiolo; Mercedes R Vieytes; Amparo Alfonso; Roberto Bermúdez; José Manuel Cifuentes; Luis Botana
Pharmacokinetic and toxicological data of spirolides after oral and intraperitoneal administration.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(2):232-7.
2011: M Carmen Louzao; Isabel R Ares; Eva Cagide; Begoña Espiña; Natalia Vilariño; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Palytoxins and cytoskeleton: An overview.
Toxicon : official journal of the International Society on Toxinology 2011;57(3):460-9.
2010: M Carmen Louzao; Begoña Espiña; Eva Cagide; Isabel R Ares; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Cytotoxic effect of palytoxin on mussel.
Toxicon : official journal of the International Society on Toxinology 2010;56(5):842-7.
2010: P Rodríguez; Amparo Alfonso; A M Botana; Mercedes R Vieytes; Luis Botana
Comparative analysis of pre- and post-column oxidation methods for detection of paralytic shellfish toxins.
Toxicon : official journal of the International Society on Toxinology 2010;56(3):448-57.
2010: Paz Otero; Amparo Alfonso; Carmen Alfonso; Mercedes R Vieytes; M Carmen Louzao; Ana M Botana; Luis Botana
New protocol to obtain spirolides from Alexandrium ostenfeldii cultures with high recovery and purity.
Biomedical chromatography : BMC 2010;24(8):878-86.
2010: Paz Otero; Sheila Pérez; Amparo Alfonso; Carmen Vale; Paula Rodríguez; Neide N Gouveia; Nuno Gouveia; João Delgado; Paulo Vale; Masahiro Hirama; Yuuki Ishihara; Jordi Molgó; Luis Botana
First toxin profile of ciguateric fish in Madeira Arquipelago (Europe).
Analytical chemistry 2010;82(14):6032-9.
2010: Paz Otero; Amparo Alfonso; Mercedes R Vieytes; Ana G Cabado; Juan M Vieites; Luis Botana
Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii.
Environmental toxicology and chemistry / SETAC 2010;29(2):301-10.
2010: Antonio Reboreda; Jorge Lago; María-José Chapela; Juan M Vieites; Luis Botana; Amparo Alfonso; Ana G Cabado
Decrease of marine toxin content in bivalves by industrial processes.
Toxicon : official journal of the International Society on Toxinology 2010;55(2-3):235-43.
2010: Begoña Espiña; M Carmen Louzao; Eva Cagide; Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytes.
British journal of pharmacology 2010;159(2):337-44.
2008: Carmen Alfonso; Nils Rehmann; Philipp Hess; Amparo Alfonso; Carolina B Wandscheer; María Abuín; Carmen Vale; Paz Otero; Mercedes R Vieytes; Luis Botana
Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies.
Analytical chemistry 2008;80(24):9672-80.
2008: Eva Alonso; Amparo Alfonso; Kristin Löber; Luis Botana
The effect of rottlerin in calcium regulation in HMC-1(560) cells is mediated by a PKC-delta independent effect.
Journal of cellular biochemistry 2008;105(1):255-61.
2008: Paula Rodriguez; Amparo Alfonso; Carmen Vale; Carmen Alfonso; Paulo Vale; Antonio Tellez; Luis Botana
First toxicity report of tetrodotoxin and 5,6,11-trideoxyTTX in the trumpet shell Charonia lampas lampas in Europe.
Analytical chemistry 2008;80(14):5622-9.
2008: Carmen Alfonso; Amparo Alfonso; Paz Otero; Paula Rodríguez; Mercedes R Vieytes; Chris Elliot; Cowan Higgins; Luis Botana
Purification of five azaspiracids from mussel samples contaminated with DSP toxins and azaspiracids.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;865(1-2):133-40.
2008: Carmen Vale; Amparo Alfonso; Mercedes R Vieytes; Xosé Manuel Romarís; Fabiola Arévalo; Ana M Botana; Luis Botana
In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction.
Analytical chemistry 2008;80(5):1770-6.
2008: Kristin Löber; Amparo Alfonso; Luis Escribano; Luis Botana
Influence of the tyrosine kinase inhibitors STI571 (Glivec), lavendustin A and genistein on human mast cell line (HMC-1(560)) activation.
Journal of cellular biochemistry 2008;103(4):1076-88.
2008: Kristin Löber; Amparo Alfonso; Luis Escribano; Luis Botana
STI571 (Glivec) affects histamine release and intracellular pH after alkalinisation in HMC-1560, 816.
Journal of cellular biochemistry 2008;103(3):865-76.
2007: C Vale-Gonzalez; María-José Pazos; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Study of the neuronal effects of ouabain and palytoxin and their binding to Na,K-ATPases using an optical biosensor.
Toxicon : official journal of the International Society on Toxinology 2007;50(4):541-52.
2007: C Alfonso; Amparo Alfonso; María-José Pazos; Mercedes R Vieytes; Takeshi Yasumoto; Anna Milandri; Roberto Poletti; Luis Botana
Extraction and cleaning methods to detect yessotoxins in contaminated mussels.
Analytical biochemistry 2007;363(2):228-38.
2007: Carmen Vale; KC Nicolaou; Michael O Frederick; Belén Gómez-Limia; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study.
Journal of medicinal chemistry 2007;50(2):356-63.
2006: Octavio Pernas-Sueiras; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
PKC and cAMP positively modulate alkaline-induced exocytosis in the human mast cell line HMC-1.
Journal of cellular biochemistry 2006;99(6):1651-63.
2006: Octavio Pernas-Sueiras; Amparo Alfonso; Mercedes R Vieytes; Alberto Orfao; Luis Escribano; Sánchez-Jiménez Francisca; Luis Botana
Calcium-pH crosstalks in the human mast cell line HMC-1: intracellular alkalinization activates calcium extrusion through the plasma membrane Ca2+-ATPase.
Journal of cellular biochemistry 2006;99(5):1397-408.
2006: Amparo Alfonso; Mercedes R Vieytes; Katsuya Ofuji; Masayuki Satake; KC Nicolaou; Michael O Frederick; Luis Botana
Azaspiracids modulate intracellular pH levels in human lymphocytes.
Biochemical and biophysical research communications 2006;346(3):1091-9.
2006: Carmen Vale-González; Amparo Alfonso; Cristina Suñol; Mercedes R Vieytes; Luis Botana
Role of the plasma membrane calcium adenosine triphosphatase on domoate-induced intracellular acidification in primary cultures of cerebelar granule cells.
Journal of neuroscience research 2006;84(2):326-37.
2006: María-José Pazos; Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor.
Chemical research in toxicology 2006;19(6):794-800.
2006: Carmen Vale; Amparo Alfonso; Cristina Suñol; Mercedes R Vieytes; Luis Botana
Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin.
Journal of neuroscience research 2006;83(8):1393-406.
2005: Carmen Alfonso; Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure.
Analytical biochemistry 2005;344(2):266-74.
2005: Octavio Pernas-Sueiras; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Mast cell exocytosis can be triggered by ammonium chloride with just a cytosolic alkalinization and no calcium increase.
Journal of cellular physiology 2005;204(3):775-84.
2005: María-José Pazos; Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor.
Chemical research in toxicology 2005;18(7):1155-60.
2005: Amparo Alfonso; Yolanda Román; Mercedes R Vieytes; Katsuya Ofuji; Masayuki Satake; Takeshi Yasumoto; Luis Botana
Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes.
Biochemical pharmacology 2005;69(11):1627-36.
2005: Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Calcium-pH crosstalks in rat mast cells: modulation by transduction signals show non-essential role for calcium in alkaline-induced exocytosis.
Biochemical pharmacology 2005;69(2):319-27.
2004: María-José Pazos; Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Juan M Vieites; Luis Botana
Resonant mirror biosensor detection method based on yessotoxin-phosphodiesterase interactions.
Analytical biochemistry 2004;335(1):112-8.
2004: Yolanda Román; Amparo Alfonso; Mercedes R Vieytes; Katsuya Ofuji; Masayuki Satake; Takeshi Yasumoto; Luis Botana
Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH.
Chemical research in toxicology 2004;17(10):1338-49.
2004: Amparo Alfonso; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
A rapid microplate fluorescence method to detect yessotoxins based on their capacity to activate phosphodiesterases.
Analytical biochemistry 2004;326(1):93-9.
2003: Amparo Alfonso; Laura A de la Rosa; Mercedes R Vieytes; Luis Botana
Dimethylsphingosine increases cytosolic calcium and intracellular pH in human T lymphocytes.
Biochemical pharmacology 2003;65(3):465-78.
2003: Amparo Alfonso; Laura A de la Rosa; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes.
Biochemical pharmacology 2003;65(2):193-208.
2002: Yolanda Román; Amparo Alfonso; M Carmen Louzao; Laura A de la Rosa; Francisco Leira; Juan M Vieites; Mercedes R Vieytes; Katsuya Ofuji; Masayuki Satake; Takeshi Yasumoto; Luis Botana
Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets.
Cellular signalling 2002;14(8):703-16.
2002: Francisco Leira; Ana G Cabado; Mercedes R Vieytes; Yolanda Roman; Amparo Alfonso; Luis Botana; Takeshi Yasumoto; Claudia Malaguti; Gian Paolo Rossini
Characterization of F-actin depolymerization as a major toxic event induced by pectenotoxin-6 in neuroblastoma cells.
Biochemical pharmacology 2002;63(11):1979-88.
2001: Yolanda Román; Amparo Alfonso; M Carmen Louzao; Mercedes R Vieytes; Luis Botana
Confocal microscopy study of the different patterns of 2-NBDG uptake in rabbit enterocytes in the apical and basal zone.
Pflügers Archiv : European journal of physiology 2001;443(2):234-9.
2001: Amparo Alfonso; MA Botana; Mercedes R Vieytes; Luis Botana
Prolactin induces calcium influx and release from intracellular pools in human T lymphocytes by activation of tyrosine kinases.
Cellular signalling 2001;13(11):819-26.
2001: Laura A de la Rosa; Amparo Alfonso; Natalia Vilariño; Mercedes R Vieytes; Takeshi Yasumoto; Luis Botana
Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases.
Cellular signalling 2001;13(10):711-6.
2001: J Lago; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Ouabain-induced enhancement of rat mast cells response. Modulation by protein phosphorylation and intracellular pH.
Cellular signalling 2001;13(7):515-24.
2001: José M Quintela; Carlos Peinador; M J Moreira; Amparo Alfonso; Luis Botana; Ricardo Riguera
Pyrazolopyrimidines: synthesis, effect on histamine release from rat peritoneal mast cells and cytotoxic activity.
European journal of medicinal chemistry 2001;36(4):321-32.
2001: Laura A de la Rosa; Amparo Alfonso; Natalia Vilariño; Mercedes R Vieytes; Luis Botana
Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin.
Biochemical pharmacology 2001;61(7):827-33.
2000: Ana G Cabado; Amparo Alfonso; Mercedes R Vieytes; Luis Botana
Hypertonicity-induced intracellular pH changes in rat mast cells.
Life sciences 2000;67(16):1969-82.
2000: Ana G Cabado; Amparo Alfonso; Mercedes R Vieytes; M González; MA Botana; Luis Botana
Crosstalk between cytosolic pH and intracellular calcium in human lymphocytes: effect of 4-aminopyridin, ammoniun chloride and ionomycin.
Cellular signalling 2000;12(8):573-81.
2000: Amparo Alfonso; Ana G Cabado; Mercedes R Vieytes; Luis Botana
Calcium-pH crosstalks in rat mast cells: cytosolic alkalinization, but not intracellular calcium release, is a sufficient signal for degranulation.
British journal of pharmacology 2000;130(8):1809-16.
2000: Amparo Alfonso; Ana G Cabado; Mercedes R Vieytes; Luis Botana
Functional compartments in rat mast cells for cAMP and calcium on histamine release.
Cellular signalling 2000;12(5):343-50.
1999: Amparo Alfonso; J Lago; MA Botana; Mercedes R Vieytes; Luis Botana
Characterization of the Na+/Ca2+ exchanger on rat mast cells. Evidence for a functional role on the regulation of the cellular response.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1999;9(2):53-71.
1998: José M Quintela; Carlos Peinador; C Veiga; Liliana González; Luis Botana; Amparo Alfonso; Ricardo Riguera
Synthesis and antiallergic activity of pyridothienopyrimidines.
Bioorganic & medicinal chemistry 1998;6(10):1911-25.
1998: Amparo Alfonso; MA Botana; Mercedes R Vieytes; Luis Botana
Sodium, PMA and calcium play an important role on intracellular pH modulation in rat mast cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1998;8(6):314-27.
1997: M N Graber; Amparo Alfonso; Donald L Gill
Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid.
The Journal of biological chemistry 1997;272(47):29546-53.
1997: M D Estévez; Mercedes R Vieytes; M Carmen Louzao; Amparo Alfonso; Natalia Vilariño; Luis Botana
The antineoplastic drug vinorelbine activates non-immunological histamine release from rat mast cells.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46(4):119-24.
1996: Donald L Gill; R T Waldron; Krystyna rys-sikora; C A Ufret-Vincenty; M N Graber; Cecile Favre; Amparo Alfonso
Calcium pools, calcium entry, and cell growth.
Bioscience reports 1996;16(2):139-57.
1996: M N Graber; Amparo Alfonso; Donald L Gill
Ca2+ pools and cell growth: arachidonic acid induces recovery of cells growth-arrested by Ca2+ pool depletion.
The Journal of biological chemistry 1996;271(2):883-8.
1995: C A Ufret-Vincenty; A D Short; Amparo Alfonso; Donald L Gill
A novel Ca2+ entry mechanism is turned on during growth arrest induced by Ca2+ pool depletion.
The Journal of biological chemistry 1995;270(45):26790-3.
1995: Amparo Alfonso; M Estévez; M Carmen Louzao; Mercedes R Vieytes; Luis Botana
Determination of phosphodiesterase activity in rat mast cells using the fluorescent cAMP analogue anthraniloyl cAMP.
Cellular signalling 1995;7(5):513-8.
1995: M D Estévez; Amparo Alfonso; Mercedes R Vieytes; M Carmen Louzao; Luis Botana
Study of the activation mechanism of human GRF(1-29)NH2 on rat mast cell histamine release.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(2):87-91.
1994: Amparo Alfonso; M Carmen Louzao; Mercedes R Vieytes; Luis Botana
Comparative study of the stability of saxitoxin and neosaxitoxin in acidic solutions and lyophilized samples.
Toxicon : official journal of the International Society on Toxinology 1994;32(12):1593-8.
1994: M Carmen Louzao; Amparo Alfonso; A M Botana; X Goenaga; Ana G Cabado; Mercedes R Vieytes; Luis Botana
Effect of lyophilization on the stability of gonyautoxins obtained from contaminated mussels.
Toxicon : official journal of the International Society on Toxinology 1994;32(7):807-17.
1994: Amparo Alfonso; MA Botana; Mercedes R Vieytes; M Carmen Louzao; Luis Botana
Effect of signal transduction pathways on the action of thapsigargin on rat mast cells. Crosstalks between cellular signalling and cytosolic pH.
Biochemical pharmacology 1994;47(10):1813-20.
1994: Amparo Alfonso; MA Botana; Mercedes R Vieytes; Luis Botana
Functional characterization of the Na(+)-H+ exchanger in rat mast cells: crosstalks between different kinase pathways.
European journal of pharmacology 1994;267(3):289-96.
1993: Mercedes R Vieytes; Ana G Cabado; Amparo Alfonso; M Carmen Louzao; A M Botana; Luis Botana
Solid-phase radioreceptor assay for paralytic shellfish toxins.
Analytical biochemistry 1993;211(1):87-93.
1992: Luis Botana; Amparo Alfonso; MA Botana; Mercedes R Vieytes; M Carmen Louzao; Ana G Cabado
Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells.
Agents and actions 1992;37(1-2):1-7.
1992: E Arnaez; Amparo Alfonso; M Estevez; Mercedes R Vieytes; M Carmen Louzao; Luis Botana
Effect of purification, theophylline and sodium fluoride on histamine release produced by antineoplastic drugs on rat mast cells. A distinctive mechanism of action for carboplatin.
Biochemical pharmacology 1992;44(3):533-8.
1992: Luis Botana; E Arnaez; Mercedes R Vieytes; Amparo Alfonso; M Carmen Louzao
Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: effect of drug combinations.
Cancer chemotherapy and pharmacology 1992;30(6):487-90.
1992: Luis Botana; E Arnaez; Mercedes R Vieytes; Amparo Alfonso; M J Bujan; M Carmen Louzao; Ana G Cabado
Non-immunological release of histamine from rat mast cells elicited by antineoplastic agents.
Cancer chemotherapy and pharmacology 1992;29(6):495-8.
1991: Mercedes R Vieytes; M Carmen Louzao; M J Bujan; Amparo Alfonso; Ana G Cabado; L F de la Cruz; Luis Botana
Lack of specific saxitoxin binding to rat mast cells.
Agents and actions 1991;33(1-2):92-3.
1991: Mercedes R Vieytes; Amparo Alfonso; M J Bujan; M Carmen Louzao; A Cavado; L F de la Cruz; Luis Botana
Changes in rat mast cell responses in sodium-free media. Lack of demonstrable sodium channel activity.
Agents and actions 1991;33(1-2):94-6.