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Ye Xiong

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Ye Xiong; Asim Mahmood; Michael Chopp
Animal models of traumatic brain injury.
Yanlu Zhang; Michael Chopp; Asim Mahmood; Yuling Meng; Changsheng Qu; Ye Xiong
Impact of inhibition of erythropoietin treatment-mediated neurogenesis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury.
Asim Mahmood; Riuzuo Ning; Changsheng Qu; Hongtao Wu; Ye Xiong; Anton Goussev; Susan Irtenkauf; Yi Li; Michael Chopp
Treatment of TBI with collagen scaffolds and human marrow stromal cells increases the expression of tissue plasminogen activator.

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All Publications

2013: Ye Xiong; Asim Mahmood; Michael Chopp
Animal models of traumatic brain injury.
Nature reviews. Neuroscience 2013;14(2):128-42.
2012: Yanlu Zhang; Michael Chopp; Asim Mahmood; Yuling Meng; Changsheng Qu; Ye Xiong
Impact of inhibition of erythropoietin treatment-mediated neurogenesis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury.
Experimental neurology 2012;235(1):336-44.
2011: Asim Mahmood; Riuzuo Ning; Changsheng Qu; Hongtao Wu; Ye Xiong; Anton Goussev; Susan Irtenkauf; Yi Li; Michael Chopp
Treatment of TBI with collagen scaffolds and human marrow stromal cells increases the expression of tissue plasminogen activator.
Journal of neurotrauma 2011;28(7):1199-207.
2011: Ruizhuo Ning; Ye Xiong; Asim Mahmood; Yanlu Zhang; Yuling Meng; Changsheng Qu; Michael Chopp
Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury.
Brain research 2011;1384():140-50.
2011: Ye Xiong; Asim Mahmood; Yuling Meng; Yanlu Zhang; Zheng Gang Zhang; Daniel C Morris; Michael Chopp
Treatment of traumatic brain injury with thymosin β₄ in rats.
Journal of neurosurgery 2011;114(1):102-15.
2010: Ye Xiong; Asim Mahmood; Michael Chopp
Neurorestorative treatments for traumatic brain injury.
Discovery medicine 2010;10(54):434-42.
2010: Changsheng Qu; Asim Mahmood; Ruizhuo Ning; Ye Xiong; Li Zhang; Jieli Chen; Hao Jiang; Michael Chopp
The treatment of traumatic brain injury with velcade.
Journal of neurotrauma 2010;27(9):1625-34.
2010: Ye Xiong; Asim Mahmood; Michael Chopp
Angiogenesis, neurogenesis and brain recovery of function following injury.
Current opinion in investigational drugs (London, England : 2000) 2010;11(3):298-308.
2010: Ye Xiong; Asim Mahmood; Changsheng Qu; Humaira Kazmi; Zheng Gang Zhang; Constance T Noguchi; Timothy Schallert; Michael Chopp
Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor.
Journal of neurotrauma 2010;27(1):205-15.
2009: Hongtao Wu; Hao Jiang; Dunyue Lu; Ye Xiong; Changsheng Qu; Dong Zhou; Asim Mahmood; Michael Chopp
Effect of simvastatin on glioma cell proliferation, migration, and apoptosis.
Neurosurgery 2009;65(6):1087-96; discussion 1096-7.
2009: Yanlu Zhang; Ye Xiong; Asim Mahmood; Yuling Meng; Changsheng Qu; Timothy Schallert; Michael Chopp
Therapeutic effects of erythropoietin on histological and functional outcomes following traumatic brain injury in rats are independent of hematocrit.
Brain research 2009;1294():153-64.
2009: Bo Li; Asim Mahmood; Dunyue Lu; Hongtao Wu; Ye Xiong; Changsheng Qu; Michael Chopp
Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.
Neurosurgery 2009;65(1):179-85; discussion 185-6.
2009: Ye Xiong; Michael Chopp; Chuan-Pu Lee
Erythropoietin improves brain mitochondrial function in rats after traumatic brain injury.
Neurological research 2009;31(5):496-502.
2009: Ye Xiong; Changsheng Qu; Asim Mahmood; Zhongwu Liu; Ruizhuo Ning; Yi Li; David L Kaplan; Timothy Schallert; Michael Chopp
Delayed transplantation of human marrow stromal cell-seeded scaffolds increases transcallosal neural fiber length, angiogenesis, and hippocampal neuronal survival and improves functional outcome after traumatic brain injury in rats.
Brain research 2009;1263():183-91.
2009: Ye Xiong; Asim Mahmood; Michael Chopp
Emerging treatments for traumatic brain injury.
Expert opinion on emerging drugs 2009;14(1):67-84.
2009: Nicole M Diotte; Ye Xiong; Jinping Gao; Balvin H L Chua; Ye-Shih Ho
Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2.
Biochimica et biophysica acta 2009;1793(2):427-38.
2008: Asim Mahmood; Anton Goussev; Dunyue Lu; Changsheng Qu; Ye Xiong; Humaira Kazmi; Michael Chopp
Long-lasting benefits after treatment of traumatic brain injury (TBI) in rats with combination therapy of marrow stromal cells (MSCs) and simvastatin.
Journal of neurotrauma 2008;25(12):1441-7.
2008: Hongtao Wu; Dunyue Lu; Hao Jiang; Ye Xiong; Changsheng Qu; Bo Li; Asim Mahmood; Dong Zhou; Michael Chopp
Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury.
Journal of neurosurgery 2008;109(4):691-8.
2008: Jinping Gao; Ye Xiong; Ye-Shih Ho; Xuwan Liu; Chu Chang Chua; Xingshun Xu; Hong Wang; Ronald Hamdy; Balvin H L Chua
Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity.
Biochimica et biophysica acta 2008;1783(10):2020-9.
2008: Ye Xiong; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Asim Mahmood; Michael Chopp
Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice.
Journal of neurosurgery 2008;109(3):510-21.
2008: Changsheng Qu; Asim Mahmood; Dunyue Lu; Anton Goussev; Ye Xiong; Michael Chopp
Treatment of traumatic brain injury in mice with marrow stromal cells.
Brain research 2008;1208():234-9.
2007: Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Michael Chopp
Role of gender in outcome after traumatic brain injury and therapeutic effect of erythropoietin in mice.
Brain research 2007;1185():301-12.
2007: Ye-Shih Ho; Ye Xiong; Dorothy S Ho; Jinping Gao; Balvin H L Chua; Harish Pai; John J Mieyal
Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia.
Free radical biology & medicine 2007;43(9):1299-312.
2007: Chu Chang Chua; Jinping Gao; Ye-Shih Ho; Ye Xiong; Xingshun Xu; Zhongyi Chen; Ronald C Hamdy; Balvin H L Chua
Overexpression of IAP-2 attenuates apoptosis and protects against myocardial ischemia/reperfusion injury in transgenic mice.
Biochimica et biophysica acta 2007;1773(4):577-83.
2007: H Helen Lin; Ye Xiong; Ye-Shih Ho; Beiyun Zhou; Ha-Van Nguyen; Hongtao Deng; Renee Lee; Yun Yen; Zea Borok; David K Ann
Transcriptional regulation by targeted expression of architectural transcription factor high mobility group A2 in salivary glands of transgenic mice.
European journal of oral sciences 2007;115(1):30-9.
2006: Renu A Kowluru; Vibhuti Kowluru; Ye Xiong; Ye-Shih Ho
Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress.
Free radical biology & medicine 2006;41(8):1191-6.
2006: Ye Xiong; Xuwan Liu; Chuan-Pu Lee; Balvin H L Chua; Ye-Shih Ho
Attenuation of doxorubicin-induced contractile and mitochondrial dysfunction in mouse heart by cellular glutathione peroxidase.
Free radical biology & medicine 2006;41(1):46-55.
2005: Ye Xiong; Feng-Shiun Shie; Jing Zhang; Chuan-Pu Lee; Ye-Shih Ho
Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase.
Journal of neurochemistry 2005;95(3):732-44.
2004: Ye-Shih Ho; Ye Xiong; Wanchao Ma; Abraham Spector; Dorothy S Ho
Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury.
The Journal of biological chemistry 2004;279(31):32804-12.
2004: Ye Xiong; Feng-Shiun Shie; Jing Zhang; Chuan-Pu Lee; Ye-Shih Ho
The protective role of cellular glutathione peroxidase against trauma-induced mitochondrial dysfunction in the mouse brain.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2004;13(3):129-37.
2001: Ye Xiong; Hong Lin; Ben D Chen; PL Peterson; Chuan-Pu Lee
Appearance of shortened Bcl-2 and Bax proteins and lack of evidence for apoptosis in rat forebrain after severe experimental traumatic brain injury.
Biochemical and biophysical research communications 2001;286(2):401-5.
2001: Ye Xiong; PL Peterson; Chuan-Pu Lee
Alterations in cerebral energy metabolism induced by traumatic brain injury.
Neurological research 2001;23(2-3):129-38.
2000: Bon H Verweij; J Paul Muizelaar; Federico Vinas; PL Peterson; Ye Xiong; Chuan-Pu Lee
Improvement in mitochondrial dysfunction as a new surrogate efficiency measure for preclinical trials: dose-response and time-window profiles for administration of the calcium channel blocker Ziconotide in experimental brain injury.
Journal of neurosurgery 2000;93(5):829-34.
2000: Bon H Verweij; J Paul Muizelaar; Federico Vinas; PL Peterson; Ye Xiong; Chuan-Pu Lee
Impaired cerebral mitochondrial function after traumatic brain injury in humans.
Journal of neurosurgery 2000;93(5):815-20.
1999: Ye Xiong; PL Peterson; Chuan-Pu Lee
Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats.
Journal of neurotrauma 1999;16(11):1067-82.
1998: Ye Xiong; PL Peterson; Bon H Verweij; Federico Vinas; J Paul Muizelaar; Chuan-Pu Lee
Mitochondrial dysfunction after experimental traumatic brain injury: combined efficacy of SNX-111 and U-101033E.
Journal of neurotrauma 1998;15(7):531-44.
1997: Ye Xiong; PL Peterson; J Paul Muizelaar; Chuan-Pu Lee
Amelioration of mitochondrial function by a novel antioxidant U-101033E following traumatic brain injury in rats.
Journal of neurotrauma 1997;14(12):907-17.
1997: Bon H Verweij; J Paul Muizelaar; Federico Vinas; PL Peterson; Ye Xiong; Chuan-Pu Lee
Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111).
Neurological research 1997;19(3):334-9.
1997: Ye Xiong; Q Gu; PL Peterson; J Paul Muizelaar; Chuan-Pu Lee
Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury.
Journal of neurotrauma 1997;14(1):23-34.
1996: Chuan-Pu Lee; Q Gu; Ye Xiong; R A Mitchell; L Ernster
P/O ratios reassessed: mitochondrial P/O ratios consistently exceed 1.5 with succinate and 2.5 with NAD-linked substrates.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(2):345-50.