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Tieyan Han

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Chemicals & Drugs

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TOP 3
Valérie Gouazé; Jing Y Yu; Richard J Bleicher; Tieyan Han; Yong-Yu Liu; Hongtao Wang; Michael M Gottesman; Arie Bitterman; Armando E Giuliano; Myles C Cabot
Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy.
Yong-Yu Liu; Tieyan Han; Jing Y Yu; Arie Bitterman; Ahn Le; Armando E Giuliano; Myles C Cabot
Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
A Senchenkov; Tieyan Han; H Wang; A E Frankel; T J Kottke; S H Kaufmann; Myles C Cabot
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.

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All Publications

2004: Valérie Gouazé; Jing Y Yu; Richard J Bleicher; Tieyan Han; Yong-Yu Liu; Hongtao Wang; Michael M Gottesman; Arie Bitterman; Armando E Giuliano; Myles C Cabot
Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy.
Molecular cancer therapeutics 2004;3(5):633-9.
2004: Yong-Yu Liu; Tieyan Han; Jing Y Yu; Arie Bitterman; Ahn Le; Armando E Giuliano; Myles C Cabot
Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
Journal of lipid research 2004;45(5):933-40.
2001: A Senchenkov; Tieyan Han; H Wang; A E Frankel; T J Kottke; S H Kaufmann; Myles C Cabot
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
Blood 2001;98(6):1927-34.
2001: A G Charles; Tieyan Han; Yong-Yu Liu; N Hansen; Armando E Giuliano; Myles C Cabot
Taxol-induced ceramide generation and apoptosis in human breast cancer cells.
Cancer chemotherapy and pharmacology 2001;47(5):444-50.
2001: Yong-Yu Liu; Tieyan Han; Armando E Giuliano; Myles C Cabot
Ceramide glycosylation potentiates cellular multidrug resistance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(3):719-30.
2000: Yong-Yu Liu; Tieyan Han; Armando E Giuliano; N Hansen; Myles C Cabot
Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance.
The Journal of biological chemistry 2000;275(10):7138-43.
1999: Yong-Yu Liu; Tieyan Han; Armando E Giuliano; S Ichikawa; Y Hirabayashi; Myles C Cabot
Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis.
Experimental cell research 1999;252(2):464-70.
1999: A Lucci; Tieyan Han; Yong-Yu Liu; Armando E Giuliano; Myles C Cabot
Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics.
International journal of oncology 1999;15(3):541-6.
1999: A Lucci; Armando E Giuliano; Tieyan Han; T Dinur; Yong-Yu Liu; A Senchenkov; Myles C Cabot
Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells.
International journal of oncology 1999;15(3):535-40.
1999: A Lucci; Tieyan Han; Yong-Yu Liu; Armando E Giuliano; Myles C Cabot
Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells.
Cancer 1999;86(2):300-11.
1999: Myles C Cabot; Armando E Giuliano; Tieyan Han; Yong-Yu Liu
SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells.
Cancer research 1999;59(4):880-5.
1999: Yong-Yu Liu; Tieyan Han; Armando E Giuliano; Myles C Cabot
Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells.
The Journal of biological chemistry 1999;274(2):1140-6.
1998: Y Lavie; Z C Zhang; H T Cao; Tieyan Han; R C Jones; Yong-Yu Liu; Michael Jarman; IR Hardcastle; Armando E Giuliano; Myles C Cabot
Tamoxifen induces selective membrane association of protein kinase C epsilon in MCF-7 human breast cancer cells.
International journal of cancer. Journal international du cancer 1998;77(6):928-32.
1998: Myles C Cabot; Tieyan Han; Armando E Giuliano
The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation.
FEBS letters 1998;431(2):185-8.
1998: A Lucci; W I Cho; Tieyan Han; Armando E Giuliano; Donald L Morton; Myles C Cabot
Glucosylceramide: a marker for multiple-drug resistant cancers.
Anticancer research 1998;18(1B):475-80.
1997: Myles C Cabot; Z Zhang; H Cao; Y Lavie; Armando E Giuliano; Tieyan Han; R C Jones
Tamoxifen activates cellular phospholipase C and D and elicits protein kinase C translocation.
International journal of cancer. Journal international du cancer 1997;70(5):567-74.
1997: Y Lavie; H t Cao; A Volner; A Lucci; Tieyan Han; V Geffen; Armando E Giuliano; Myles C Cabot
Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells.
The Journal of biological chemistry 1997;272(3):1682-7.
1996: Myles C Cabot; Armando E Giuliano; A Volner; Tieyan Han
Tamoxifen retards glycosphingolipid metabolism in human cancer cells.
FEBS letters 1996;394(2):129-31.