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Guy Rouleau

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Alanna Grant; Ridha Joober; Guy Rouleau; Ferid Fathalli; Cecilia Flores
Association between schizophrenia and genetic variation in DCC: a case-control study.
Jean-François Lepage; Alvaro Pascual-Leone; Guy Rouleau; Myriam Srour; Vincent Beaulé; Maryse Lassonde; Hugo Théoret
Neurophysiological investigation of congenital mirror movements in a patient with agenesis of the corpus callosum.
Alexandra Vaccaro; Dina Aggad; Pierre Drapeau; Guy Rouleau; Arnaud Tauffenberger; J Alex Parker
Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.

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All Publications

2012: Alanna Grant; Ridha Joober; Guy Rouleau; Ferid Fathalli; Cecilia Flores
Association between schizophrenia and genetic variation in DCC: a case-control study.
Schizophrenia research 2012;137(1-3):26-31.
2012: Jean-François Lepage; Alvaro Pascual-Leone; Guy Rouleau; Myriam Srour; Vincent Beaulé; Maryse Lassonde; Hugo Théoret
Neurophysiological investigation of congenital mirror movements in a patient with agenesis of the corpus callosum.
Brain stimulation 2012;5(2):137-40.
2012: Alexandra Vaccaro; Dina Aggad; Pierre Drapeau; Guy Rouleau; Arnaud Tauffenberger; J Alex Parker
Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.
PloS one 2012;7(2):e31321.
2011: Hussein Daoud; Patrick A Dion; Nicolas Dupré; Lucette Lacomblez; Sandra Martins; Vincent Meininger; Pierre Provencher; Véronique Belzil; William Camu; Mike Sabbagh; Guy Rouleau
Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis.
Archives of neurology 2011;68(6):739-42.
2011: Simon L Girard; Lan Xiong; Patrick A Dion; Guy Rouleau
Where are the missing pieces of the schizophrenia genetics puzzle?
Current opinion in genetics & development 2011;21(3):310-6.
2011: Fadi F Hamdan; Julie Gauthier; Sylvia Dobrzeniecka; Anne Lortie; Laurent Mottron; Michel Vanasse; Guy D'Anjou; Jean Claude Lacaille; Guy Rouleau; Jacques L Michaud
Intellectual disability without epilepsy associated with STXBP1 disruption.
European journal of human genetics : EJHG 2011;19(5):607-9.
2011: Fadi F Hamdan; Hussein Daoud; Amélie Piton; Julie Gauthier; Sylvia Dobrzeniecka; Marie-Odile Krebs; Ridha Joober; Jean-Claude Lacaille; Amélie Nadeau; Jeff M Milunsky; Zhenyuan Wang; Lionel Carmant; Laurent Mottron; Miriam H Beauchamp; Guy Rouleau; Jacques L Michaud
De novo SYNGAP1 mutations in nonsyndromic intellectual disability and autism.
Biological psychiatry 2011;69(9):898-901.
2011: Hussein Daoud; Paul N Valdmanis; François Gros-Louis; Véronique Belzil; Dan Spiegelman; Edouard Henrion; Ousmane Diallo; Anne Desjarlais; Julie Gauthier; William Camu; Patrick Dion; Guy Rouleau
Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis.
Archives of neurology 2011;68(5):587-93.
2011: Karli K McDonald; Anaïs Aulas; Laurie Destroismaisons; Sarah Pickles; Evghenia Beleac; William Camu; Guy Rouleau; Christine Vande Velde
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1.
Human molecular genetics 2011;20(7):1400-10.
2011: Véronique V Belzil; Hussein Daoud; Patrick A Dion; Guy Rouleau
No effect on SOD1 splicing by TARDP or FUS mutations.
Archives of neurology 2011;68(3):395-6.
2011: Veronique V Belzil; Hussein Daoud; Judith St-Onge; Anne Desjarlais; Jean-Pierre Bouchard; Nicolas Dupre; Lucette Lacomblez; François Salachas; Pierre-François Pradat; Vincent Meininger; William Camu; Patrick Dion; Guy Rouleau
Identification of novel FUS mutations in sporadic cases of amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2011;12(2):113-7.
2011: Véronique V Belzil; Judith St-Onge; Hussein Daoud; Anne Desjarlais; Jean-Pierre Bouchard; Nicolas Dupré; William Camu; Patrick Dion; Guy Rouleau
Identification of a FUS splicing mutation in a large family with amyotrophic lateral sclerosis.
Journal of human genetics 2011;56(3):247-9.
2011: Véronique V Belzil; Hussein Daoud; Anne Desjarlais; Jean-Pierre Bouchard; Nicolas Dupré; William Camu; Patrick A Dion; Guy Rouleau
Analysis of OPTN as a causative gene for amyotrophic lateral sclerosis.
Neurobiology of aging 2011;32(3):555.e13-4.
2011: Masoud Shekarabi; Adèle Salin-Cantegrel; Janet Laganière; Rébecca Gaudet; Patrick Dion; Guy Rouleau
Cellular expression of the K+-Cl- cotransporter KCC3 in the central nervous system of mouse.
Brain research 2011;1374():15-26.
2011: Paul N Valdmanis; Nicolas Dupré; Mathieu Lachance; Shawn J Stochmanski; Veronique V Belzil; Patrick A Dion; Isabelle Thiffault; Bernard Brais; Lyle Weston; Louis Saint-Amant; Mark E Samuels; Guy Rouleau
A mutation in the RNF170 gene causes autosomal dominant sensory ataxia.
Brain : a journal of neurology 2011;134(Pt 2):602-7.
2011: Gauthier Julie; Fadi F Hamdan; Guy Rouleau
A strategy to identify de novo mutations in common disorders such as autism and schizophrenia.
Journal of visualized experiments : JoVE 2011;(52):.
2011: Tracy Tucker; Alexandre Montpetit; David Chai; Susanna Chan; Sebastien Chenier; Bradley P Coe; Allen Delaney; Patrice Eydoux; Wan L Lam; Sylvie Langlois; Emmanuelle Lemyre; Marco Marra; Hong Qian; Guy Rouleau; David Vincent; Jacques L Michaud; Jan M Friedman
Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardation.
BMC medical genomics 2011;4():25.
2011: N D Merner; P A Dion; Guy Rouleau
Recent advances in the genetics of distal hereditary motor neuropathy give insight to a disease mechanism involving copper homeostasis that may extend to other motor neuron disorders.
Clinical genetics 2011;79(1):23-34.
2010: Emilie Fortier; Anne Noreau; Franco Lepore; Michel Boivin; Daniel Pérusse; Guy Rouleau; Mario Beauregard
Early impact of 5-HTTLPR polymorphism on the neural correlates of sadness.
Neuroscience letters 2010;485(3):261-5.
2010: Fadi F Hamdan; Hussein Daoud; Daniel Rochefort; Amélie Piton; Julie Gauthier; Mathieu Langlois; Gila Foomani; Sylvia Dobrzeniecka; Marie-Odile Krebs; Ridha Joober; Ronald G Lafrenière; Jean-Claude Lacaille; Laurent Mottron; Pierre Drapeau; Miriam H Beauchamp; Michael S Phillips; Eric Fombonne; Guy Rouleau; Jacques L Michaud
De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment.
American journal of human genetics 2010;87(5):671-8.
2010: Hussein Daoud; Véronique Belzil; Patrick A Dion; Guy Rouleau
Chromosome 9p21 in amyotrophic lateral sclerosis: the plot thickens.
Lancet neurology 2010;9(10):945-7.
2010: Julien Tarabeux; Nathalie Champagne; Edna Brustein; Fadi F Hamdan; Julie Gauthier; Mathieu Lapointe; Claudia Maios; Amélie Piton; Dan Spiegelman; Edouard Henrion; Bruno Millet; Judith L Rapoport; Lynn E Delisi; Ridha Joober; Ferid Fathalli; Eric Fombonne; Laurent Mottron; Nadine Forget-Dubois; Michel Boivin; Jacques L Michaud; Ronald G Lafrenière; Pierre Drapeau; Marie-Odile Krebs; Guy Rouleau
De novo truncating mutation in Kinesin 17 associated with schizophrenia.
Biological psychiatry 2010;68(7):649-56.
2010: Georgina Macintyre; Tyler Alford; Lan Xiong; Guy Rouleau; Philip Tibbo; Diane W Cox
Association of NPAS3 exonic variation with schizophrenia.
Schizophrenia research 2010;120(1-3):143-9.
2010: Matthieu Y Pasco; Hélène Catoire; Alex Parker; Bernard Brais; Guy Rouleau; Christian Néri
Cross-talk between canonical Wnt signaling and the sirtuin-FoxO longevity pathway to protect against muscular pathology induced by mutant PABPN1 expression in C. elegans.
Neurobiology of disease 2010;38(3):425-33.
2010: Lan Xiong; Jacques Montplaisir; Alex Desautels; Amina Barhdadi; Gustavo Turecki; Anastasia Levchenko; Pascale Thibodeau; Marie-Pierre Dubé; Claudia Gaspar; Guy Rouleau
Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases.
Archives of neurology 2010;67(5):617-22.
2010: Myriam Srour; Jean-Baptiste Rivière; Jessica M T Pham; Marie-Pierre Dubé; Simon Girard; Steves Morin; Patrick Dion; Géraldine Asselin; Daniel Rochefort; Pascale Hince; Sabrina Diab; Naser Sharafaddinzadeh; Sylvain Chouinard; Hugo Théoret; Frédéric Charron; Guy Rouleau
Mutations in DCC cause congenital mirror movements.
Science (New York, N.Y.) 2010;328(5978):592.
2010: Julie Gauthier; Nathalie Champagne; Ronald G Lafrenière; Lan Xiong; Dan Spiegelman; Edna Brustein; Mathieu Lapointe; Huashan Peng; Mélanie Côté; Anne Noreau; Fadi F Hamdan; Anjené M Addington; Judith L Rapoport; Lynn E Delisi; Marie-Odile Krebs; Ridha Joober; Ferid Fathalli; Fayçal Mouaffak; Ali P Haghighi; Christian Néri; Marie-Pierre Dubé; Mark E Samuels; Claude Marineau; Eric A Stone; Philip Awadalla; Philip A Barker; Salvatore Carbonetto; Pierre Drapeau; Guy Rouleau
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(17):7863-8.
2010: Edor Kabashi; Li Lin; Miranda L Tradewell; Patrick A Dion; Valérie Bercier; Patrick Bourgouin; Daniel Rochefort; Samar Bel Hadj; Heather D Durham; Christine Vande Velde; Guy Rouleau; Pierre Drapeau
Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo.
Human molecular genetics 2010;19(4):671-83.
2010: Matthieu Y Pasco; dante rotili; Lucia Altucci; Francesca Farina; Guy Rouleau; Antonello Mai; Christian Néri
Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specific sirtinol analogues.
Journal of medicinal chemistry 2010;53(3):1407-11.
2010: Fadi F Hamdan; Julie Gauthier; Guy Rouleau; Jacques L Michaud
[De novo mutations in SYNGAP1 associated with non-syndromic mental retardation].
Médecine sciences : M/S 2010;26(2):133-5.
2010: C Graeni; Frank Stepper; Matthias Sturzenegger; A Merlo; Dominique J Verlaan; Frederick Andermann; Christian R Baumann; F Bonassin; D Georgiadis; Ralf W Baumgartner; Guy Rouleau; Adrian M Siegel
Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families.
Neurosurgical review 2010;33(1):47-51.
2009: Francois Gros-Louis; Peter M Andersen; Nicolas Dupre; Makoto Urushitani; Patrick Dion; Frederique Souchon; Monique D'Amour; William Camu; Vincent Meininger; Jean-Pierre Bouchard; Guy Rouleau; Jean-Pierre Julien
Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(51):21777-82.
2009: Paul N Valdmanis; Veronique V Belzil; James Lee; Patrick Dion; Judith St-Onge; Pascale Hince; Benoit Funalot; Philippe Couratier; Pierre Clavelou; William Camu; Guy Rouleau
A mutation that creates a pseudoexon in SOD1 causes familial ALS.
Annals of human genetics 2009;73(Pt 6):652-7.
2009: Patrick A Dion; Hussein Daoud; Guy Rouleau
Genetics of motor neuron disorders: new insights into pathogenic mechanisms.
Nature reviews. Genetics 2009;10(11):769-82.
2009: V V Belzil; Paul N Valdmanis; Patrick Dion; H Daoud; Edor Kabashi; A Noreau; J Gauthier; P Hince; A Desjarlais; Jean-Pierre Bouchard; Lucette Lacomblez; François Salachas; P-F Pradat; William Camu; Vincent Meininger; Nicolas Dupré; Guy Rouleau
Mutations in FUS cause FALS and SALS in French and French Canadian populations.
Neurology 2009;73(15):1176-9.
2009: Jean-Baptiste Rivière; Lan Xiong; Anastasia Levchenko; Judith St-Onge; Claudia Gaspar; Yves Dion; Paul Lespérance; Geneviève Tellier; Francois Richer; Sylvain Chouinard; Guy Rouleau
Association of intronic variants of the BTBD9 gene with Tourette syndrome.
Archives of neurology 2009;66(10):1267-72.
2009: M Srour; M Philibert; M-H Dion; André Duquette; Francois Richer; Guy Rouleau; S Chouinard
Familial congenital mirror movements: report of a large 4-generation family.
Neurology 2009;73(9):729-31.
2009: Fadi F Hamdan; Amélie Piton; Julie Gauthier; Anne Lortie; François Dubeau; Sylvia Dobrzeniecka; Dan Spiegelman; Anne Noreau; Stéphanie Pellerin; Mélanie Côté; Edouard Henrion; Eric Fombonne; Laurent Mottron; Claude Marineau; Pierre Drapeau; Ronald G Lafrenière; Jean Claude Lacaille; Guy Rouleau; Jacques L Michaud
De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy.
Annals of neurology 2009;65(6):748-53.
2009: C Messaed; Guy Rouleau
Molecular mechanisms underlying polyalanine diseases.
Neurobiology of disease 2009;34(3):397-405.
2009: Paul N Valdmanis; Hussein Daoud; Patrick Dion; Guy Rouleau
Recent advances in the genetics of amyotrophic lateral sclerosis.
Current neurology and neuroscience reports 2009;9(3):198-205.
2009: Jeanne M McCaffery; Qing Ling Duan; Nancy Frasure-Smith; Amina Barhdadi; Francois Lespérance; Pierre Théroux; Guy Rouleau; Marie-Pierre Dubé
Genetic predictors of depressive symptoms in cardiac patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(3):381-8.
2009: Julie Gauthier; Dan Spiegelman; Amélie Piton; Ronald G Lafrenière; Sandra Laurent; Judith St-Onge; Line Lapointe; Fadi F Hamdan; Patrick Cossette; Laurent Mottron; Eric Fombonne; Ridha Joober; Claude Marineau; Pierre Drapeau; Guy Rouleau
Novel de novo SHANK3 mutation in autistic patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(3):421-4.
2009: Qing Ling Duan; Karen Binkley; Guy Rouleau
Genetic analysis of Factor XII and bradykinin catabolic enzymes in a family with estrogen-dependent inherited angioedema.
The Journal of allergy and clinical immunology 2009;123(4):906-10.
2009: Jean-Baptiste Rivière; Patrick Dion; Masoud Shekarabi; Nathalie Girard; Laurence Faivre; Ronald G Lafrenière; Mark Samuels; Guy Rouleau
[Mutations in the HSN2 exon of WNK1 cause hereditary sensory neuropathy type II].
Médecine sciences : M/S 2009;25(3):235-8.
2009: Paul N Valdmanis; Dominique J Verlaan; Guy Rouleau
The proportion of mutations predicted to have a deleterious effect differs between gain and loss of function genes in neurodegenerative disease.
Human mutation 2009;30(3):E481-9.
2009: Fadi F Hamdan; Julie Gauthier; Dan Spiegelman; Anne Noreau; Yan Yang; Stéphanie Pellerin; Sylvia Dobrzeniecka; Mélanie Côté; Elizabeth Perreau-Linck; Elizabeth Perreault-Linck; Lionel Carmant; Guy D'Anjou; Eric Fombonne; Anjene M Addington; Judy Rapoport; Lynn E Delisi; Marie-Odile Krebs; Faycal Mouaffak; Ridha Joober; Laurent Mottron; Pierre Drapeau; Claude Marineau; Ronald G Lafrenière; Jean-Claude Lacaille; Guy Rouleau; Jacques L Michaud
Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation.
The New England journal of medicine 2009;360(6):599-605.
2009: Edor Kabashi; Hussein Daoud; Jean-Baptiste Rivière; Paul N Valdmanis; Paul N Valdamanis; Patrick Bourgouin; Pierre Provencher; Emmanuelle Pourcher; Patrick Dion; Nicolas Dupré; Guy Rouleau
No TARDBP mutations in a French Canadian population of patients with Parkinson disease.
Archives of neurology 2009;66(2):281-2.
2009: H Daoud; Paul N Valdmanis; Edor Kabashi; P Dion; Nicolas Dupré; W Camu; Vincent Meininger; Guy Rouleau
Contribution of TARDBP mutations to sporadic amyotrophic lateral sclerosis.
Journal of medical genetics 2009;46(2):112-4.
2009: Jm Friedman; Shelin Adam; Laura Arbour; Linlea Armstrong; Agnes Baross; Patricia Birch; Cornelius Boerkoel; Susanna Chan; David Chai; Allen D Delaney; Stephane Flibotte; William T Gibson; Sylvie Langlois; Emmanuelle Lemyre; H Irene Li; Patrick MacLeod; Joan Mathers; Jacques L Michaud; Barbara C McGillivray; Millan S Patel; Hong Qian; Guy Rouleau; Margot I Van Allen; Siu Li Yong; Farah R Zahir; Patrice Eydoux; Marco A Marra
Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization.
BMC genomics 2009;10():526.
2009: Adolfo Sequeira; Firoza Mamdani; Carl Ernst; Marquis P Vawter; William E Bunney; Veronique Lebel; Sonia Rehal; Tim Klempan; Alain Gratton; Chawki Benkelfat; Guy Rouleau; Naguib Mechawar; Gustavo Turecki
Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression.
PloS one 2009;4(8):e6585.
2008: Amélie Piton; Jacques L Michaud; Huashan Peng; Swaroop Aradhya; Julie Gauthier; Laurent Mottron; Nathalie Champagne; Ronald G Lafrenière; Fadi F Hamdan; Ridha Joober; Eric Fombonne; Claude Marineau; Patrick Cossette; Marie-Pierre Dubé; Pejmun Haghighi; Pierre Drapeau; Philip A Barker; Salvatore Carbonetto; Guy Rouleau
Mutations in the calcium-related gene IL1RAPL1 are associated with autism.
Human molecular genetics 2008;17(24):3965-74.
2008: Inge A Meijer; Ana A Simoes-Lopes; Sandra Laurent; Tanya Katz; Judith St-Onge; Dominique J Verlaan; Nicolas Dupré; Manon Thibault; Johanne Mathurin; Jean-Pierre Bouchard; Guy Rouleau
A novel duplication confirms the involvement of 5q23.2 in autosomal dominant leukodystrophy.
Archives of neurology 2008;65(11):1496-501.
2008: Adèle Salin-Cantegrel; Masoud Shekarabi; Sébastien Holbert; Patrick Dion; Daniel Rochefort; Janet Laganière; Sandra Dacal; Pascale Hince; Liliane Karemera; Claudia Gaspar; Jean-Yves Lapointe; Guy Rouleau
HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3.
Human molecular genetics 2008;17(17):2703-11.
2008: François Gros-Louis; Jasna Kriz; Edor Kabashi; Jonathan McDearmid; Stéphanie Millecamps; Makoto Urushitani; Li Lin; Patrick Dion; Qinzhang Zhu; Pierre Drapeau; Jean-Pierre Julien; Guy Rouleau
Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish.
Human molecular genetics 2008;17(17):2691-702.
2008: Jeremy J Moeller; Robert Macaulay; Paul N Valdmanis; Lyle E Weston; Guy Rouleau; Nicolas Dupré
Autosomal dominant sensory ataxia: a neuroaxonal dystrophy.
Acta neuropathologica 2008;116(3):331-6.
2008: Paul N Valdmanis; Edor Kabashi; A Dyck; P Hince; J Lee; Patrick Dion; M D'Amour; F Souchon; Jean-Pierre Bouchard; François Salachas; Vincent Meininger; P M Andersen; William Camu; Nicolas Dupré; Guy Rouleau
Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden.
Neurology 2008;71(7):514-20.
2008: Samar Khoury; Guy Rouleau; Pierre Rompré; Pierre Mayer; Jacques Y Montplaisir; Gilles J Lavigne
A significant increase in breathing amplitude precedes sleep bruxism.
Chest 2008;134(2):332-7.
2008: Hélène Catoire; Matthieu Y Pasco; Aida Abu-Baker; Sébastien Holbert; Cendrine Tourette; Bernard Brais; Guy Rouleau; Alex Parker; Christian Néri
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.
Human molecular genetics 2008;17(14):2108-17.
2008: Masoud Shekarabi; Nathalie Girard; Jean-Baptiste Rivière; Patrick Dion; Martin Houle; André Toulouse; Ronald G Lafrenière; Freya Vercauteren; Pascale Hince; janet laganiere; Daniel Rochefort; Laurence Faivre; Mark Samuels; Guy Rouleau
Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II.
The Journal of clinical investigation 2008;118(7):2496-505.
2008: Edor Kabashi; Paul N Valdmanis; Patrick Dion; Dan Spiegelman; Brendan J McConkey; Christine Vande Velde; Jean-Pierre Bouchard; Lucette Lacomblez; Ksenia Pochigaeva; Francois Salachas; Pierre-Francois Pradat; William Camu; Vincent Meininger; Nicolas Dupre; Guy Rouleau
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Nature genetics 2008;40(5):572-4.
2008: Arnaud F Klein; Mitsuru Ebihara; Christine Alexander; Marie-Josée Dicaire; A Marie-Josée Sasseville; Yves Langelier; Guy Rouleau; Bernard Brais
PABPN1 polyalanine tract deletion and long expansions modify its aggregation pattern and expression.
Experimental cell research 2008;314(8):1652-66.
2008: Paul N Valdmanis; Nicolas Dupré; Guy Rouleau
A locus for primary lateral sclerosis on chromosome 4ptel-4p16.1.
Archives of neurology 2008;65(3):383-6.
2008: Peter Kinirons; Dominique J Verlaan; Marie-Pierre Dubé; Josée Poirier; Charles Deacon; Anne Lortie; Jean-François Clément; Richard Desbiens; Lionel Carmant; Cecile Cieuta-Walti; Michael Shevell; Guy Rouleau; Patrick Cossette
A novel locus for idiopathic generalized epilepsy in French-Canadian families maps to 10p11.
American journal of medical genetics. Part A 2008;146A(5):578-84.
2008: Lan Xiong; Anastasia Levchenko; Jacques Montplaisir; Jean-Baptiste Rivière; Pascale Thibodeau; Judith St-Onge; Claudia Gaspar; Alex Desautels; Paul Lespérance; Sylvain Chouinard; Gustavo Turecki; Guy Rouleau
Genetic association studies of neurotensin gene and restless legs syndrome in French Canadians.
Sleep medicine 2008;9(3):273-82.
2008: Paul N Valdmanis; Edor Kabashi; Patrick A Dion; Guy Rouleau
ALS predisposition modifiers: knock NOX, who's there? SOD1 mice still are.
European journal of human genetics : EJHG 2008;16(2):140-2.
2008: Paul N Valdmanis; Guy Rouleau
Genetics of familial amyotrophic lateral sclerosis.
Neurology 2008;70(2):144-52.
2008: Ferid Fathalli; Guy Rouleau; Lan Xiong; Karim Tabbane; Chawki Benkelfat; Rosherrie Deguzman; Danics Zoltan; Samarthji Lal; Sarogini D'cruz; Ridha Joober
No association between the DRD3 Ser9Gly polymorphism and schizophrenia.
Schizophrenia research 2008;98(1-3):98-104.
2007: Hana Zouk; Alexander McGirr; Véronique Lebel; Chawki Benkelfat; Guy Rouleau; Gustavo Turecki
The effect of genetic variation of the serotonin 1B receptor gene on impulsive aggressive behavior and suicide.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(8):996-1002.
2007: Edor Kabashi; Paul N Valdmanis; Patrick Dion; Guy Rouleau
Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis?
Annals of neurology 2007;62(6):553-9.
2007: Lan Xiong; Patrick Dion; Jacques Montplaisir; Anastasia Levchenko; Pascale Thibodeau; Liliane Karemera; Jean-Baptiste Rivière; Judith St-Onge; Claudia Gaspar; Marie-Pierre Dubé; Alex Desautels; Gustavo Turecki; Guy Rouleau
Molecular genetic studies of DMT1 on 12q in French-Canadian restless legs syndrome patients and families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):911-7.
2007: Sandra Martins; Francesc Calafell; Claudia Gaspar; Virginia C N Wong; Isabel Silveira; Garth A Nicholson; Ewout R Brunt; Lisbeth Tranebjaerg; Giovanni Stevanin; Mingli Hsieh; bing-wen soong; Leal Loureiro; Alexandra Dürr; Shoji Tsuji; Mitsunori Watanabe; Laura B Jardim; Paola Giunti; Olaf Riess; Laura P W Ranum; Alexis Brice; Guy Rouleau; Paula Coutinho; António Amorim; Jorge Sequeiros
Asian origin for the worldwide-spread mutational event in Machado-Joseph disease.
Archives of neurology 2007;64(10):1502-8.
2007: A Salin-Cantegrel; Jean-Baptiste Rivière; Nicolas Dupré; François M Charron; Masoud Shekarabi; L Karéméra; Claudia Gaspar; Jürgen Horst; Mustafa Tekin; G Deda; A Krause; M M Lippert; Michèl A A P Willemsen; R Jarrar; Jean-Yves Lapointe; Guy Rouleau
Distal truncation of KCC3 in non-French Canadian HMSN/ACC families.
Neurology 2007;69(13):1350-5.
2007: Sultan Ahmad; Leif Dahllund; Anders B Eriksson; Dennis Hellgren; Urban Karlsson; Per-Eric Lund; Inge A Meijer; Luc Meury; Tracy Mills; Adrian Moody; Anne Morinville; John Morten; Dajan O'Donnell; Carina Raynoschek; Hugh Salter; Guy Rouleau; Johannes J Krupp
A stop codon mutation in SCN9A causes lack of pain sensation.
Human molecular genetics 2007;16(17):2114-21.
2007: Nicolas Dupré; Jean-Baptiste Rivière; Richard H Myers; Pierre Provencher; Emmanuelle Pourcher; François Emond; Guy Rouleau
LRRK2 is not a significant cause of Parkinson's disease in French-Canadians.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2007;34(3):333-5.
2007: Nicolas Dupré; François Gros-Louis; Nicolas Chrestian; Steve Verreault; Denis Brunet; Danielle de Verteuil; Bernard Brais; Jean-Pierre Bouchard; Guy Rouleau
Clinical and genetic study of autosomal recessive cerebellar ataxia type 1.
Annals of neurology 2007;62(1):93-8.
2007: Pedro Adolfo Sequeira; Tim Klempan; Lilian Canetti; Jarlath ffrench-Mullen; Chawki Benkelfat; Guy Rouleau; Gustavo Turecki
Patterns of gene expression in the limbic system of suicides with and without major depression.
Molecular psychiatry 2007;12(7):640-55.
2007: christian beetz; Stephan Zuchner; Allison Ashley-Koch; Michaela Auer-Grumbach; Paula Byrne; Patrick F Chinnery; Michael Hutchinson; Christopher J McDermott; Inge A Meijer; Anders O H Nygren; Margaret Pericak-Vance; Angela Pyle; Guy Rouleau; Jörg Schickel; Pamela J Shaw; Thomas Deufel
Linkage to a known gene but no mutation identified: comprehensive reanalysis of SPG4 HSP pedigrees reveals large deletions as the sole cause.
Human mutation 2007;28(7):739-40.
2007: Catalina Lopez de Lara; Jelena Brezo; Guy Rouleau; Alain Lesage; Mimi Dumont; Martin Alda; Chawki Benkelfat; Gustavo Turecki
Effect of tryptophan hydroxylase-2 gene variants on suicide risk in major depression.
Biological psychiatry 2007;62(1):72-80.
2007: Inge A Meijer; Patrick Dion; Sandra Laurent; Nicolas Dupré; Bernard Brais; Annie Levert; Jack Puymirat; Marie-France Rioux; Michel Sylvain; Peng-Peng Zhu; Cynthia Soderblom; Julia Stadler; Craig Blackstone; Guy Rouleau
Characterization of a novel SPG3A deletion in a French-Canadian family.
Annals of neurology 2007;61(6):599-603.
2007: Christiane Messaed; Patrick Dion; Aida Abu-Baker; Daniel Rochefort; janet laganiere; Bernard Brais; Guy Rouleau
Soluble expanded PABPN1 promotes cell death in oculopharyngeal muscular dystrophy.
Neurobiology of disease 2007;26(3):546-57.
2007: Qing Ling Duan; Marie-Pierre Dubé; Nancy Frasure-Smith; Amina Barhdadi; François Lesperance; Pierre Théroux; Judith St-Onge; Guy Rouleau; Jeanne M McCaffery
Additive effects of obesity and TCF7L2 variants on risk for type 2 diabetes among cardiac patients.
Diabetes care 2007;30(6):1621-3.
2007: Lan Xiong; K Jang; Jacques Montplaisir; Anastasia Levchenko; Pascale Thibodeau; Claudia Gaspar; Gustavo Turecki; Guy Rouleau
Canadian restless legs syndrome twin study.
Neurology 2007;68(19):1631-3.
2007: Inge A Meijer; Nicolas Dupré; Bernard Brais; Patrick Cossette; Judith St-Onge; Marie-France Rioux; Melanie Benard; Guy Rouleau
SPG4 founder effect in French Canadians with hereditary spastic paraplegia.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2007;34(2):211-4.
2007: Martin Lemay; NICOLAS TERMOZ; P Lesperance; Sylvain Chouinard; Guy Rouleau; Francois Richer
Postural control anomalies in children with Tourette syndrome.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2007;179(3):525-30.
2007: Nicolas Dupré; Paul N Valdmanis; Jean-Pierre Bouchard; Guy Rouleau
Autosomal dominant primary lateral sclerosis.
Neurology 2007;68(14):1156-7.
2007: Nicolas Dupré; Jean-Pierre Bouchard; François Gros-Louis; Guy Rouleau
[Mutations in SYNE-1 lead to a newly discovered form of autosomal recessive cerebellar ataxia].
Médecine sciences : M/S 2007;23(3):261-2.
2007: Paul N Valdmanis; Nicolas Dupre; Jean-Pierre Bouchard; William Camu; François Salachas; Vincent Meininger; Michael Strong; Guy Rouleau
Three families with amyotrophic lateral sclerosis and frontotemporal dementia with evidence of linkage to chromosome 9p.
Archives of neurology 2007;64(2):240-5.
2007: Aida Abu-Baker; Guy Rouleau
Oculopharyngeal muscular dystrophy: recent advances in the understanding of the molecular pathogenic mechanisms and treatment strategies.
Biochimica et biophysica acta 2007;1772(2):173-85.
2007: Guy Rouleau; Inge A Meijer
CSCI/RCPSC Henry Friesen lecture: the past and the future of neurogenetics.
Clinical and investigative medicine. Médecine clinique et experimentale 2007;30(6):E269-73.
2007: Firoza Mamdani; Pedro Adolfo Sequeira; Martin Alda; Paul Grof; Guy Rouleau; Gustavo Turecki
No association between the PREP gene and lithium responsive bipolar disorder.
BMC psychiatry 2007;7():9.
2007: Paul N Valdmanis; Inge A Meijer; Annie Reynolds; Adrienne Lei; Patrick MacLeod; David Schlesinger; Mayana Zatz; Evan Reid; Patrick Dion; Pierre Drapeau; Guy Rouleau
Mutations in the KIAA0196 gene at the SPG8 locus cause hereditary spastic paraplegia.
American journal of human genetics 2007;80(1):152-61.
2007: François Gros-Louis; Nicolas Dupré; Patrick Dion; Michael A Fox; Sandra Laurent; Steve Verreault; Joshua R Sanes; Jean-Pierre Bouchard; Guy Rouleau
Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia.
Nature genetics 2007;39(1):80-5.
2006: Paul N Valdmanis; Denis Brunet; Judith St-Onge; L Weston; Guy Rouleau; Nicolas Dupré
A founder haplotype for autosomal dominant sensory ataxia in Eastern Canada.
Neurology 2006;67(12):2239-42.
2006: Hitesh K Jindal; Kazumi Yoshinaga; Pil-Soo Seo; Mohini Lutchman; Patrick Dion; Guy Rouleau; Toshihiko Hanada; Athar H Chishti
Purification of the NF2 tumor suppressor protein from human erythrocytes.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2006;33(4):394-402.
2006: Giuseppe Molinaro; Qing Ling Duan; Chagnon Miguel; Marie Eve Moreau; P Simon; P Clavel; Sylvie Lavaud; Guy Boileau; Guy Rouleau; Yves Lepage; Albert Adam; Jacques Chanard
Kinin-dependent hypersensitivity reactions in hemodialysis: metabolic and genetic factors.
Kidney international 2006;70(10):1823-31.
2006: Adam Torkamanzehi; Patricia Boksa; Mouhssine Ayoubi; Marie-Eve Fortier; N M K Ng Ying Kin; Emil Skamene; Guy Rouleau; Ridha Joober
Identification of informative strains and provisional QTL mapping of amphetamine (AMPH)-induced locomotion in recombinant congenic strains (RCS) of mice.
Behavior genetics 2006;36(6):903-13.
2006: François Gros-Louis; Claudia Gaspar; Guy Rouleau
Genetics of familial and sporadic amyotrophic lateral sclerosis.
Biochimica et biophysica acta 2006;1762(11-12):956-72.
2006: Anastasia Levchenko; Sylvie Provost; J Y Montplaisir; Lan Xiong; Judith St-Onge; Pascale Thibodeau; Jean-Baptiste Rivière; Alex Desautels; Gustavo Turecki; Marie-Pierre Dubé; Guy Rouleau
A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13.
Neurology 2006;67(5):900-1.
2006: A Marie-Josée Sasseville; Antoine W Caron; Lucie Bourget; Arnaud F Klein; Marie-Josée Dicaire; Guy Rouleau; Bernard Massie; Yves Langelier; Bernard Brais
The dynamism of PABPN1 nuclear inclusions during the cell cycle.
Neurobiology of disease 2006;23(3):621-9.
2006: I Thiffault; Marie-France Rioux; M Tetreault; J Jarry; L Loiselle; J Poirier; François Gros-Louis; Jean Mathieu; Michel Vanasse; Guy Rouleau; Jean-Pierre Bouchard; Jacques Lesage; Bernard Brais
A new autosomal recessive spastic ataxia associated with frequent white matter changes maps to 2q33-34.
Brain : a journal of neurology 2006;129(Pt 9):2332-40.
2006: Dominique J Verlaan; M-P Dubé; Judith St-Onge; A Noreau; Julie Roussel; N Satgé; M C Wallace; Guy Rouleau
A new locus for autosomal dominant intracranial aneurysm, ANIB4, maps to chromosome 5p15.2-14.3.
Journal of medical genetics 2006;43(6):e31.
2006: Ryan R Brinkman; Marie-Pierre Dubé; Guy Rouleau; Andrew C Orr; Mark E Samuels
Human monogenic disorders - a source of novel drug targets.
Nature reviews. Genetics 2006;7(4):249-60.
2006: Jeanne M McCaffery; Nancy Frasure-Smith; Marie-Pierre Dubé; Pierre Théroux; Guy Rouleau; Qingling Duan; François Lespérance
Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin.
Psychosomatic medicine 2006;68(2):187-200.
2006: Sharlene Murdoch; Ugljesa Djuric; Batool Mazhar; Muhieddine Seoud; Rabia Khan; Rork Kuick; Rashmi Bagga; Renate Kircheisen; Asangla Ao; Bhawna Ratti; Samir Hanash; Guy Rouleau; Rima Slim
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans.
Nature genetics 2006;38(3):300-2.
2006: Julie Gauthier; Ridha Joober; Marie-Pierre Dubé; Judith St-Onge; Anna Bonnel; D Gariépy; Sandra Laurent; R Najafee; H Lacasse; L St-Charles; Eric Fombonne; Laurent Mottron; Guy Rouleau
Autism spectrum disorders associated with X chromosome markers in French-Canadian males.
Molecular psychiatry 2006;11(2):206-13.
2006: Catalina Lopez de Lara; Alexandre Dumais; Guy Rouleau; Alain Lesage; Mimi Dumont; Nadia Chawky; Martin Alda; Chawki Benkelfat; Gustavo Turecki
STin2 variant and family history of suicide as significant predictors of suicide completion in major depression.
Biological psychiatry 2006;59(2):114-20.
2006: Sarojini Sengupta; Lan Xiong; Ferid Fathalli; Chawki Benkelfat; Karim Tabbane; Zoltan Danics; Alain Labelle; Samarthji Lal; Marie-Odile Krebs; Guy Rouleau; Ridha Joober
Association study of the trinucleotide repeat polymorphism within SMARCA2 and schizophrenia.
BMC genetics 2006;7():34.
2006: Pedro Adolfo Sequeira; Fuad G Gwadry; Jarlath ffrench-Mullen; Lilian Canetti; Yves Gingras; Robert A Casero; Guy Rouleau; Chawki Benkelfat; Gustavo Turecki
Implication of SSAT by gene expression and genetic variation in suicide and major depression.
Archives of general psychiatry 2006;63(1):35-48.
2005: Dominique J Verlaan; Julie Roussel; Sandra B Laurent; C E Elger; Adrian M Siegel; Guy Rouleau
CCM3 mutations are uncommon in cerebral cavernous malformations.
Neurology 2005;65(12):1982-3.
2005: Alexandre Dumais; Alain Lesage; Martin Alda; Guy Rouleau; Mimi Dumont; Nadia Chawky; M Roy; J J Mann; Chawki Benkelfat; Gustavo Turecki
Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men.
The American journal of psychiatry 2005;162(11):2116-24.
2005: Julie Turnbull; Hannes Lohi; Jennifer A Kearney; Guy Rouleau; Antonio V Delgado-Escueta; Miriam H Meisler; Patrick Cossette; Berge A Minassian
Sacred disease secrets revealed: the genetics of human epilepsy.
Human molecular genetics 2005;14 Spec No. 2():2491-2500.
2005: Adriana Díaz-Anzaldúa; Jean-Baptiste Rivière; Marie-Pierre Dubé; Ridha Joober; Judith Saint-Onge; Yves Dion; Paul Lespérance; Francois Richer; Sylvain Chouinard; Guy Rouleau
Chromosome 11-q24 region in Tourette syndrome: association and linkage disequilibrium study in the French Canadian population.
American journal of medical genetics. Part A 2005;138A(3):225-8.
2005: Qing Ling Duan; Borzoo Nikpoor; Marie-Pierre Dube; Giuseppe Molinaro; Inge A Meijer; Patrick Dion; Daniel Rochefort; Judith Saint-Onge; Leah Flury; Nancy Brown; James V Gainer; Jean-Lucien Rouleau; Angelo Agostoni; Massimo Cugno; Pierre Simon; Pierre Clavel; Jacky Potier; Bassem Wehbe; Seddik Benarbia; Julien Marc-Aurele; Jacques Chanard; Tatiana Foroud; Albert Adam; Guy Rouleau
A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors.
American journal of human genetics 2005;77(4):617-26.
2005: André Toulouse; Faith Au-Yeung; Claudia Gaspar; Julie Roussel; Patrick Dion; Guy Rouleau
Ribosomal frameshifting on MJD-1 transcripts with long CAG tracts.
Human molecular genetics 2005;14(18):2649-60.
2005: Borzoo Nikpoor; Qing Ling Duan; Guy Rouleau
Acute adverse reactions associated with angiotensin-converting enzyme inhibitors: genetic factors and therapeutic implications.
Expert opinion on pharmacotherapy 2005;6(11):1851-6.
2005: Aida Abu-Baker; Simon Laganiere; Xueping Fan; janet laganiere; Bernard Brais; Guy Rouleau
Cytoplasmic targeting of mutant poly(A)-binding protein nuclear 1 suppresses protein aggregation and toxicity in oculopharyngeal muscular dystrophy.
Traffic (Copenhagen, Denmark) 2005;6(9):766-79.
2005: Julie Turnbull; Hannes Lohi; Jennifer A Kearney; Guy Rouleau; Antonio V Delgado-Escueta; Miriam H Meisler; Patrick Cossette; Berge A Minassian
Sacred disease secrets revealed: the genetics of human epilepsy.
Human molecular genetics 2005;14(17):2491-500.
2005: Ridha Joober; Guy Rouleau; Samarthji Lal; David Bloom; Pierre Lalonde; Alain Labelle; Chawki Benkelfat
Increased prevalence of schizophrenia spectrum disorders in relatives of neuroleptic-nonresponsive schizophrenic patients.
Schizophrenia research 2005;77(1):35-41.
2005: Stéphanie Millecamps; benoit Gentil; François Gros-Louis; Guy Rouleau; Jean-Pierre Julien
Alsin is partially associated with centrosome in human cells.
Biochimica et biophysica acta 2005;1745(1):84-100.
2005: Julie Gauthier; Giovana V de Amorim; Gevork N Mnatzakanian; Carol Saunders; John B Vincent; Sylvie Toupin; David Kauffman; Judith St-Onge; Sandra Laurent; Patrick M Macleod; Berge A Minassian; Guy Rouleau
Clinical stringency greatly improves mutation detection in Rett syndrome.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2005;32(3):321-6.
2005: Michael E Baser; Lisa Kuramoto; Ryan Woods; Harry Joe; Jan M Friedman; Andrew J Wallace; Richard T Ramsden; S Olschwang; EK Bijlsma; M Kalamarides; L Papi; R Kato; J Carroll; C Lázaro; F Joncourt; Dilys M Parry; Guy Rouleau; D G R Evans
The location of constitutional neurofibromatosis 2 (NF2) splice site mutations is associated with the severity of NF2.
Journal of medical genetics 2005;42(7):540-6.
2005: Martin Alda; Paul Grof; Guy Rouleau; Gustavo Turecki; L Trevor Young
Investigating responders to lithium prophylaxis as a strategy for mapping susceptibility genes for bipolar disorder.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(6):1038-45.
2005: Katel Roddier; T Thomas; G Marleau; A M Gagnon; Marie-Josée Dicaire; A St-Denis; I Gosselin; A M Sarrazin; A Larbrisseau; Marie Lambert; Michel Vanasse; Daniel Gaudet; Guy Rouleau; Bernard Brais
Two mutations in the HSN2 gene explain the high prevalence of HSAN2 in French Canadians.
Neurology 2005;64(10):1762-7.
2005: Alex Desautels; Gustavo Turecki; Jacques Montplaisir; Lan Xiong; Arthur S Walters; Bruce L Ehrenberg; Kateri Brisebois; Amelie K Desautels; Yves Gingras; William G Johnson; Elio Lugaresi; Giorgio Coccagna; Daniel Picchietti; Alice Lazzarini; Guy Rouleau
Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity.
Archives of neurology 2005;62(4):591-6.
2005: Louis-Philippe Corbeil-Girard; Arnaud F Klein; A Marie-Josée Sasseville; Hugo Lavoie; Marie-Josée Dicaire; Anik Saint-Denis; Martin Pagé; André Duranceau; François Codère; Jean-Pierre Bouchard; George Karpati; Guy Rouleau; Bernard Massie; Yves Langelier; Bernard Brais
PABPN1 overexpression leads to upregulation of genes encoding nuclear proteins that are sequestered in oculopharyngeal muscular dystrophy nuclear inclusions.
Neurobiology of disease 2005;18(3):551-67.
2005: Patrick Dion; Vijayalakshmi Shanmugam; Claudia Gaspar; Christiane Messaed; Inge A Meijer; André Toulouse; janet laganiere; Julie Roussel; Daniel Rochefort; Simon Laganiere; Carol Allen; George Karpati; Jean-Pierre Bouchard; Bernard Brais; Guy Rouleau
Transgenic expression of an expanded (GCG)13 repeat PABPN1 leads to weakness and coordination defects in mice.
Neurobiology of disease 2005;18(3):528-36.
2005: Osman El-Maarri; Muhieddine Seoud; Jean-Baptiste Rivière; Johannes Oldenburg; Jörn Walter; Guy Rouleau; Rima Slim
Patients with familial biparental hydatidiform moles have normal methylation at imprinted genes.
European journal of human genetics : EJHG 2005;13(4):486-90.
2005: Rebecca S Devon; Claudia Schwab; Justin D Topp; Paul C Orban; Yu-Zhou Yang; Terry D Pape; Jeffrey R Helm; Tara-Lynne Davidson; Daniel A Rogers; François Gros-Louis; Guy Rouleau; Bruce F Horazdovsky; Blair R Leavitt; Michael R Hayden
Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood.
Neurobiology of disease 2005;18(2):243-57.
2005: Adrian M Siegel; Helmut Bertalanffy; Johannes Dichgans; C E Elger; H Hopf; N Hopf; M Keidel; A Kleider; G Nowak; R A Pfeiffer; J Schramm; S Spuck; H Stefan; U Sure; Christian R Baumann; Guy Rouleau; Dominique J Verlaan; E Andermann; Frederick Andermann
[Familial cavernous malformations of the central nervous system. A clinical and genetic study of 15 German families].
Der Nervenarzt 2005;76(2):175-80.
2005: Lan Xiong; Guy Rouleau; Lynn E Delisi; Judith St-Onge; Robert Najafee; Jean-Baptiste Rivière; Chawki Benkelfat; Karim Tabbane; Ferid Fathalli; Zoltan Danics; Alain Labelle; Samarthji Lal; Ridha Joober
CAA insertion polymorphism in the 3'UTR of Nogo gene on 2p14 is not associated with schizophrenia.
Brain research. Molecular brain research 2005;133(1):153-6.
2005: Julie Gauthier; Anna Bonnel; Judith St-Onge; Liliane Karemera; Sandra Laurent; Laurent Mottron; Eric Fombonne; Ridha Joober; Guy Rouleau
NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):74-5.
2005: Patrick Cossette; Anne Lortie; Michel Vanasse; Jean-Marc Saint-Hilaire; Guy Rouleau
Autosomal dominant juvenile myoclonic epilepsy and GABRA1.
Advances in neurology 2005;95():255-63.
2004: K K Grewal; M G Stefanelli; Inge A Meijer; Collette K Hand; Guy Rouleau; E J Ives
A founder effect in three large Newfoundland families with a novel clinically variable spastic ataxia and supranuclear gaze palsy.
American journal of medical genetics. Part A 2004;131(3):249-54.
2004: Dominique J Verlaan; Sandra B Laurent; Guy Rouleau; Adrian M Siegel
No CCM2 mutations in a cohort of 31 sporadic cases.
Neurology 2004;63(10):1979.
2004: François Gros-Louis; Roxanne C Larivière; Geneviève Gowing; Sandra Laurent; William Camu; Jean-Pierre Bouchard; Vincent Meininger; Guy Rouleau; Jean-Pierre Julien
A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis.
The Journal of biological chemistry 2004;279(44):45951-6.
2004: Jean-Baptiste Rivière; Dominique J Verlaan; Masoud Shekarabi; Ronald G Lafrenière; Mélanie Bénard; Vazken M Der Kaloustian; Zuhayr Shbaklo; Guy Rouleau
A mutation in the HSN2 gene causes sensory neuropathy type II in a Lebanese family.
Annals of neurology 2004;56(4):572-5.
2004: Inge A Meijer; Patrick Cossette; Julie Roussel; Melanie Benard; Sylvie Toupin; Guy Rouleau
A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1-10q24.1.
Annals of neurology 2004;56(4):579-82.
2004: Paul Lespérance; N Djerroud; A Diaz Anzaldua; Guy Rouleau; Sylvain Chouinard; Francois Richer
Restless legs in Tourette syndrome.
Movement disorders : official journal of the Movement Disorder Society 2004;19(9):1084-7.
2004: Anastasia Levchenko; Yvonne Robitaille; Michael J Strong; Guy Rouleau
TAU mutations are not a predominant cause of frontotemporal dementia in Canadian patients.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2004;31(3):363-7.
2004: Paul N Valdmanis; A A Simões Lopes; François Gros-Louis; J D Stewart; Guy Rouleau; Nicolas Dupré
A novel neurodegenerative disease characterised by posterior column ataxia and pyramidal tract involvement maps to chromosome 8p12-8q12.1.
Journal of medical genetics 2004;41(8):634-9.
2004: Anastasia Levchenko; Jacques-Yves Montplaisir; Marie-Pierre Dubé; Jean-Baptiste Riviere; Judith St-Onge; Gustavo Turecki; Lan Xiong; Pascale Thibodeau; Alex Desautels; Dominique J Verlaan; Guy Rouleau
The 14q restless legs syndrome locus in the French Canadian population.
Annals of neurology 2004;55(6):887-91.
2004: Adriana Díaz-Anzaldúa; Ridha Joober; Jean-Baptiste Rivière; Yves Dion; Paul Lespérance; Sylvain Chouinard; Francois Richer; Guy Rouleau
Association between 7q31 markers and Tourette syndrome.
American journal of medical genetics. Part A 2004;127A(1):17-20.
2004: Dominique J Verlaan; Sandra B Laurent; Daniel L Rochefort; Christina L Liquori; Douglas A Marchuk; Adrian M Siegel; Guy Rouleau
CCM2 mutations account for 13% of cases in a large collection of kindreds with hereditary cavernous malformations.
Annals of neurology 2004;55(5):757-8.
2004: Ronald G Lafreniere; Marcia L E MacDonald; Marie-Pierre Dube; Julie MacFarlane; Mary O'Driscoll; Bernard Brais; Sebastien Meilleur; Ryan R Brinkman; Owen Dadivas; Terry Pape; Christele Platon; Christopher C Radomski; Jenni Risler; Jay Thompson; Ana-Maria Guerra-Escobio; Gudarz Davar; Xandra O Breakefield; Simon N Pimstone; Roger C Green; William Pryse-Phillips; Y Paul Goldberg; H Banfield Younghusband; Michael R Hayden; Robin Sherrington; Guy Rouleau; Mark E Samuels
Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates.
American journal of human genetics 2004;74(5):1064-73.
2004: Dominique J Verlaan; Sandra B Laurent; U Sure; Helmut Bertalanffy; Eva Andermann; Frederick Andermann; Guy Rouleau; Adrian M Siegel
CCM1 mutation screen of sporadic cases with cerebral cavernous malformations.
Neurology 2004;62(7):1213-5.
2004: Adriana Díaz-Anzaldúa; Ridha Joober; Jean-Baptiste Rivière; Yves Dion; Paul Lespérance; Francois Richer; Sylvain Chouinard; Guy Rouleau
Tourette syndrome and dopaminergic genes: a family-based association study in the French Canadian founder population.
Molecular psychiatry 2004;9(3):272-7.
2004: Hélène-Farnase Jafari-Schluep; Jawad Khoris; Véronique Mayeux-Portas; C Hand; Guy Rouleau; William Camu
[Superoxyde dismutase 1 gene abnormalities in familial amyotrophic lateral sclerosis: phenotype/genotype correlations. The French experience and review of the literature].
Revue neurologique 2004;160(1):44-50.
2004: Alex Desautels; Gustavo Turecki; Lan Xiong; Daniel Rochefort; Jacques Montplaisir; Guy Rouleau
Mutational analysis of neurotensin in familial restless legs syndrome.
Movement disorders : official journal of the Movement Disorder Society 2004;19(1):90-4.
2003: Alex Desautels; Gustavo Turecki; Jacques Montplaisir; Kateri Brisebois; Amélie K Desautels; Benoît Adam; Guy Rouleau
Analysis of CAG repeat expansions in restless legs syndrome.
Sleep 2003;26(8):1055-7.
2003: Nadine Forget-Dubois; Daniel Pérusse; Gustavo Turecki; Alain Girard; Jean-Michel Billette; Guy Rouleau; Michel Boivin; Jocelyn Malo; Richard E Tremblay
Diagnosing zygosity in infant twins: physical similarity, genotyping, and chorionicity.
Twin research : the official journal of the International Society for Twin Studies 2003;6(6):479-85.
2003: Collette K Hand; Rebecca S Devon; François Gros-Louis; Daniel Rochefort; Jawad Khoris; Vincent Meininger; Jean-Pierre Bouchard; William Camu; Michael R Hayden; Guy Rouleau
Mutation screening of the ALS2 gene in sporadic and familial amyotrophic lateral sclerosis.
Archives of neurology 2003;60(12):1768-71.
2003: François Gros-Louis; Sandra Laurent; Ana Amelia Simões Lopes; Jawad Khoris; Vincent Meininger; William Camu; Guy Rouleau
Absence of mutations in the hypoxia response element of VEGF in ALS.
Muscle & nerve 2003;28(6):774-5.
2003: Christina L Liquori; Michel J Berg; Adrian M Siegel; Elizabeth Huang; Jon S Zawistowski; T'Prien Stoffer; Dominique J Verlaan; Fiyinfolu Balogun; Lori Hughes; Tracey P Leedom; Nicholas W Plummer; Milena Cannella; Vittorio Maglione; Ferdinando Squitieri; Eric W Johnson; Guy Rouleau; Louis J Ptacek; Douglas A Marchuk
Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations.
American journal of human genetics 2003;73(6):1459-64.
2003: Hugo Lavoie; Francois Debeane; Quoc-Dien Trinh; Jean-Francois Turcotte; Louis-Philippe Corbeil-Girard; Marie-Josée Dicaire; Anik Saint-Denis; Martin Pagé; Guy Rouleau; Bernard Brais
Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains.
Human molecular genetics 2003;12(22):2967-79.
2003: Aida Abu-Baker; Christiane Messaed; janet laganiere; Claudia Gaspar; Bernard Brais; Guy Rouleau
Involvement of the ubiquitin-proteasome pathway and molecular chaperones in oculopharyngeal muscular dystrophy.
Human molecular genetics 2003;12(20):2609-23.
2003: Robert K Koenekoop; Magali Loyer; Collette K Hand; Huda Al Mahdi; Olga Dembinska; Raquel Beneish; Julie Racine; Guy Rouleau
Novel RPGR mutations with distinct retinitis pigmentosa phenotypes in French-Canadian families.
American journal of ophthalmology 2003;136(4):678-87.
2003: Elayne M Chan; Edwin J Young; Leonarda Ianzano; Iulia Munteanu; Xiaochu Zhao; Constantine C Christopoulos; Giuliano Avanzini; Maurizio Elia; Cameron Ackerley; Nebojsa J Jovic; Saeed Bohlega; Eva Andermann; Guy Rouleau; Antonio V Delgado-Escueta; Berge A Minassian; Stephen W Scherer
Mutations in NHLRC1 cause progressive myoclonus epilepsy.
Nature genetics 2003;35(2):125-7.
2003: Elayne M Chan; D E Bulman; Andrew D Paterson; Julie Turnbull; Eva Andermann; F Andermann; Guy Rouleau; Antonio V Delgado-Escueta; Stephen W Scherer; Berge A Minassian
Genetic mapping of a new Lafora progressive myoclonus epilepsy locus (EPM2B) on 6p22.
Journal of medical genetics 2003;40(9):671-5.
2003: Rebecca S Devon; Jeffrey R Helm; Guy Rouleau; Y Leitner; Tally Lerman-Sagie; D Lev; Michael R Hayden
The first nonsense mutation in alsin results in a homogeneous phenotype of infantile-onset ascending spastic paralysis with bulbar involvement in two siblings.
Clinical genetics 2003;64(3):210-5.
2003: Xueping Fan; Christiane Messaed; Patrick Dion; janet laganiere; Bernard Brais; George Karpati; Guy Rouleau
HnRNP A1 and A/B interaction with PABPN1 in oculopharyngeal muscular dystrophy.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2003;30(3):244-51.
2003: André Toulouse; Daniel Rochefort; Julie Roussel; Ridha Joober; Guy Rouleau
Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia.
Genomics 2003;82(2):162-71.
2003: Maxwell S H Laurans; Michael L DiLuna; Dana Shin; Faheem Niazi; Jennifer R Voorhees; Carol Nelson-Williams; Eric W Johnson; Adrian M Siegel; Gary K Steinberg; Michel J Berg; rmichael Scott; Gioacchino Tedeschi; T Peter Enevoldson; John Anson; Guy Rouleau; Christopher S Ogilvy; Issam A Awad; Richard P Lifton; Murat Gunel
Mutational analysis of 206 families with cavernous malformations.
Journal of neurosurgery 2003;99(1):38-43.
2003: Nicolas Dupré; Heidi C Howard; Jean Mathieu; George Karpati; Michel Vanasse; Jean-Pierre Bouchard; Stirling Carpenter; Guy Rouleau
Hereditary motor and sensory neuropathy with agenesis of the corpus callosum.
Annals of neurology 2003;54(1):9-18.
2003: Osman El-Maarri; Muhieddine Seoud; Philippe Coullin; Ursula Herbiniaux; Johannes Oldenburg; Guy Rouleau; Rima Slim
Maternal alleles acquiring paternal methylation patterns in biparental complete hydatidiform moles.
Human molecular genetics 2003;12(12):1405-13.
2003: Pedro Adolfo Sequeira; Caroline Kim; Monique Seguin; Alain Lesage; Nadia Chawky; Alex Desautels; Michel Tousignant; Claude Vanier; Olivier Lipp; Chawki Benkelfat; Guy Rouleau; Gustavo Turecki
Wolfram syndrome and suicide: Evidence for a role of WFS1 in suicidal and impulsive behavior.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;119B(1):108-13.
2003: Nicolas Dupré; Dominique J Verlaan; Collette K Hand; Sandra B Laurent; Gustavo Turecki; W Jeptha Davenport; Nicola Acciarri; Johannes Dichgans; Akio Ohkuma; Adrian M Siegel; Guy Rouleau
Linkage to the CCM2 locus and genetic heterogeneity in familial cerebral cavernous malformation.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2003;30(2):122-8.
2003: Julie Gauthier; Ridha Joober; Laurent Mottron; Sandra Laurent; Marketa Fuchs; Violaine De Kimpe; Guy Rouleau
Mutation screening of FOXP2 in individuals diagnosed with autistic disorder.
American journal of medical genetics. Part A 2003;118A(2):172-5.
2003: Heidi C Howard; Nicolas Dupré; Jean Mathieu; Jean-Pierre Bouchard; Guy Rouleau
[Severe neuropathy with agenesis of the corpus callosum].
Médecine sciences : M/S 2003;19(4):414-6.
2003: Gustavo Turecki; Pedro Adolfo Sequeira; Yves Gingras; Monique Séguin; Alain Lesage; Michel Tousignant; Nadia Chawky; Claude Vanier; Olivier Lipp; Chawki Benkelfat; Guy Rouleau
Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;118B(1):36-40.
2003: Xueping Fan; Guy Rouleau
Progress in understanding the pathogenesis of oculopharyngeal muscular dystrophy.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2003;30(1):8-14.
2003: Patrick Cossette; Andrew Loukas; Ronald G Lafrenière; Daniel Rochefort; Erik Harvey-Girard; David S Ragsdale; Robert J Dunn; Guy Rouleau
Functional characterization of the D188V mutation in neuronal voltage-gated sodium channel causing generalized epilepsy with febrile seizures plus (GEFS).
Epilepsy research 2003;53(1-2):107-17.
2003: Kenji Yamamoto; Joseph F Cubells; Joel Gelernter; Chawki Benkelfat; Pierre Lalonde; David Bloom; Samarthji Lal; Alain Labelle; Gustavo Turecki; Guy Rouleau; Ridha Joober
Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;117B(1):33-8.
2003: François Gros-Louis; Inge A Meijer; Collette K Hand; Marie-Pierre Dubé; Daune L MacGregor; Marie-Hélène Seni; Rebecca S Devon; Michael R Hayden; Frederick Andermann; Eva Andermann; Guy Rouleau
An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred.
Annals of neurology 2003;53(1):144-5.
2002: Alex Desautels; Martin Michaud; Jacques Montplaisir; Gustavo Turecki; Guy Rouleau
[Restless leg syndrome: clinical aspects, etiology and genetic factors].
Revue neurologique 2002;158(12 Pt 1):1225-31.
2002: Heidi C Howard; David B Mount; Daniel Rochefort; Nellie Byun; Nicolas Dupré; Jianming Lu; Xuemo Fan; Luyan Song; Jean-Baptiste Rivière; Claude Prévost; Jürgen Horst; Alessandro Simonati; Beate Lemcke; Rick Welch; Roger England; Frank Q Zhan; Adriana Mercado; William B Siesser; Alfred L George; Michael P McDonald; Jean-Pierre Bouchard; Jean Mathieu; Eric Delpire; Guy Rouleau
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.
Nature genetics 2002;32(3):384-92.
2002: Y Zhao; Ravinesh Kumar; Michael E Baser; D G R Evans; A Wallace; Lan Kluwe; Victor-Felix Mautner; Dilys M Parry; Guy Rouleau; Harry Joe; Jan M Friedman
Intrafamilial correlation of clinical manifestations in neurofibromatosis 2 (NF2).
Genetic epidemiology 2002;23(3):245-59.
2002: Ridha Joober; Patricia Boksa; Chawki Benkelfat; Guy Rouleau
Genetics of schizophrenia: from animal models to clinical studies.
Journal of psychiatry & neuroscience : JPN 2002;27(5):336-47.
2002: Alex Desautels; Gustavo Turecki; Jacques Montplaisir; Kateri Brisebois; Pedro Adolfo Sequeira; B Adam; Guy Rouleau
Evidence for a genetic association between monoamine oxidase A and restless legs syndrome.
Neurology 2002;59(2):215-9.
2002: Heidi C Howard; Marie-Pierre Dubé; Claude Prévost; Jean-Pierre Bouchard; Jean Mathieu; Guy Rouleau
Fine mapping the candidate region for peripheral neuropathy with or without agenesis of the corpus callosum in the French Canadian population.
European journal of human genetics : EJHG 2002;10(7):406-12.
2002: Ridha Joober; Julie Gauthier; Samarthji Lal; David Bloom; Pierre Lalonde; Guy Rouleau; Chawki Benkelfat; Alain Labelle
Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test.
Archives of general psychiatry 2002;59(7):662-3.
2002: Patrick Cossette; Lidong Liu; Kateri Brisebois; Haiheng Dong; Anne Lortie; Michel Vanasse; Jean-Marc Saint-Hilaire; Lionel Carmant; Andrei Verner; Wei-Yang Lu; Yu Tian Wang; Guy Rouleau
Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy.
Nature genetics 2002;31(2):184-9.
2002: Dominique J Verlaan; Adrian M Siegel; Guy Rouleau
Krit1 missense mutations lead to splicing errors in cerebral cavernous malformation.
American journal of human genetics 2002;70(6):1564-7.
2002: Dominique J Verlaan; W Jeptha Davenport; H Stefan; U Sure; Adrian M Siegel; Guy Rouleau
Cerebral cavernous malformations: mutations in Krit1.
Neurology 2002;58(6):853-7.
2002: Inge A Meijer; Collette K Hand; K K Grewal; M G Stefanelli; E J Ives; Guy Rouleau
A locus for autosomal dominant hereditary spastic ataxia, SAX1, maps to chromosome 12p13.
American journal of human genetics 2002;70(3):763-9.
2002: Collette K Hand; Guy Rouleau
Familial amyotrophic lateral sclerosis.
Muscle & nerve 2002;25(2):135-59.
2002: Inge A Meijer; Collette K Hand; Patrick Cossette; Denise A Figlewicz; Guy Rouleau
Spectrum of SPG4 mutations in a large collection of North American families with hereditary spastic paraplegia.
Archives of neurology 2002;59(2):281-6.
2002: Ridha Joober; Guy Rouleau; Samarthji Lal; Michael Dixon; Gillian A O'Driscoll; Roberta Palmour; Lawrence Annable; David Bloom; Pierre Lalonde; Alain Labelle; Chawki Benkelfat
Neuropsychological impairments in neuroleptic-responder vs. -nonresponder schizophrenic patients and healthy volunteers.
Schizophrenia research 2002;53(3):229-38.
2002: Collette K Hand; Jawad Khoris; François Salachas; François Gros-Louis; Ana Amélia Simões Lopes; Véronique Mayeux-Portas; Carl G Brewer; Robert H Brown; Vincent Meininger; William Camu; Guy Rouleau
A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q.
American journal of human genetics 2002;70(1):251-6.
2001: Alex Desautels; Gustavo Turecki; Jacques Montplaisir; Pedro Adolfo Sequeira; Andrei Verner; Guy Rouleau
Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q.
American journal of human genetics 2001;69(6):1266-70.
2001: Patrícia Maciel; Maria do Carmo Costa; Anabela Ferro; M Rousseau; C S Santos; Claudia Gaspar; José Barros; Guy Rouleau; Paula Coutinho; Jorge Sequeiros
Improvement in the molecular diagnosis of Machado-Joseph disease.
Archives of neurology 2001;58(11):1821-7.
2001: Alex Desautels; Gustavo Turecki; Jacques Montplaisir; N Ftouhi-Paquin; Martin Michaud; V A Chouinard; Guy Rouleau
Dopaminergic neurotransmission and restless legs syndrome: a genetic association analysis.
Neurology 2001;57(7):1304-6.
2001: Xueping Fan; Patrick Dion; janet laganiere; Bernard Brais; Guy Rouleau
Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death.
Human molecular genetics 2001;10(21):2341-51.
2001: Shinji Hadano; Collette K Hand; Hitoshi Osuga; Yoshiko Yanagisawa; Asako Otomo; Rebecca S Devon; N Miyamoto; Junko Showguchi-Miyata; Y Okada; Roshni R Singaraja; D A Figlewicz; T Kwiatkowski; B A Hosler; Tally Lerman-Sagie; Jennifer Skaug; Jamal Nasir; R H Brown; Stephen W Scherer; Guy Rouleau; Michael R Hayden; Joh-E Ikeda
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.
Nature genetics 2001;29(2):166-73.
2001: Gustavo Turecki; Paul Grof; Eva Grof; V D'Souza; L Lebuis; Claude Marineau; Patrizia Cavazzoni; Anne Duffy; Christine Bétard; P Zvolský; Carrie Robertson; Carl G Brewer; Thomas J Hudson; Guy Rouleau; Martin Alda
Mapping susceptibility genes for bipolar disorder: a pharmacogenetic approach based on excellent response to lithium.
Molecular psychiatry 2001;6(5):570-8.
2001: M Jannatipour; Patrick Dion; S Khan; Hitesh K Jindal; Xiaotang Fan; Josée Laganière; Athar H Chishti; Guy Rouleau
Schwannomin isoform-1 interacts with syntenin via PDZ domains.
The Journal of biological chemistry 2001;276(35):33093-100.
2001: B Nikpoor; Gustavo Turecki; C Fournier; Pierre Théroux; Guy Rouleau
A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians.
American heart journal 2001;142(2):336-9.
2001: Martin Alda; D Keller; Eva Grof; Gustavo Turecki; Patrizia Cavazzoni; Anne Duffy; Guy Rouleau; Paul Grof; L Trevor Young
Is lithium response related to G(s)alpha levels in transformed lymphoblasts from subjects with bipolar disorder?
Journal of affective disorders 2001;65(2):117-22.
2001: Anny Fortin; Eduardo Diez; Daniel Rochefort; Line Laroche; Danielle Malo; Guy Rouleau; Philippe Gros; Emil Skamene
Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.
Genomics 2001;74(1):21-35.
2001: A Pramatarova; Josée Laganière; Julie Roussel; Kateri Brisebois; Guy Rouleau
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):3369-74.
2001: N Ftouhi-Paquin; Martin Alda; Paul Grof; N Chretien; Guy Rouleau; Gustavo Turecki
Identification of three polymorphisms in the translated region of PLC-gamma1 and their investigation in lithium responsive bipolar disorder.
American journal of medical genetics 2001;105(3):301-5.
2001: K Yamamoto; David Bloom; S La; Gustavo Turecki; Ridha Joober; Chawki Benkelfat; Pierre Lalonde; Alain Labelle; Guy Rouleau
Polymorphism in the cell division cycle 45 like gene and schizophrenia.
American journal of medical genetics 2001;105(2):214-5.
2001: W Jeptha Davenport; Adrian M Siegel; Johannes Dichgans; P Drigo; I Mammi; P Pereda; Nicholas W Wood; Guy Rouleau
CCM1 gene mutations in families segregating cerebral cavernous malformations.
Neurology 2001;56(4):540-3.
2001: Nicolas Dupré; L Cossette; Collette K Hand; Jean-Pierre Bouchard; Guy Rouleau; Jack Puymirat
A founder mutation in French-Canadian families with X-linked hereditary neuropathy.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2001;28(1):51-5.
2001: Collette K Hand; Véronique Mayeux-Portas; Jawad Khoris; Valérie Briolotti; Pierre Clavelou; William Camu; Guy Rouleau
Compound heterozygous D90A and D96N SOD1 mutations in a recessive amyotrophic lateral sclerosis family.
Annals of neurology 2001;49(2):267-71.
2001: Claudia Gaspar; Iscia Lopes-Cendes; S Hayes; Jun Goto; K Arvidsson; Adelaide Dias; Isabel Silveira; Patrícia Maciel; Paula Coutinho; M Lima; Y X Zhou; bing-wen soong; Masahiko Watanabe; Paola Giunti; Giovanni Stevanin; Olaf Riess; H Sasaki; M Hsieh; G A Nicholson; E Brunt; J J Higgins; M Lauritzen; Lisbeth Tranebjaerg; V Volpini; Nicholas W Wood; Laura P W Ranum; Shoji Tsuji; Alexis Brice; Jorge Sequeiros; Guy Rouleau
Ancestral origins of the Machado-Joseph disease mutation: a worldwide haplotype study.
American journal of human genetics 2001;68(2):523-8.
2001: Shinji Hadano; Yoshiko Yanagisawa; Jennifer Skaug; Keith Fichter; Jamal Nasir; Duane W Martindale; BF Koop; Stephen W Scherer; Donald W Nicholson; Guy Rouleau; J Ikeda; Michael R Hayden
Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2.
Genomics 2001;71(2):200-13.
2001: Y Ichikawa; Jun Goto; Masahira Hattori; Atsushi Toyoda; K Ishii; Seon-Yong Jeong; Hideji Hashida; N Masuda; Katsuhisa Ogata; F Kasai; Momoki Hirai; Patrícia Maciel; Guy Rouleau; Yoshiyuki Sakaki; Ichiro Kanazawa
The genomic structure and expression of MJD, the Machado-Joseph disease gene.
Journal of human genetics 2001;46(7):413-22.
2001: Gustavo Turecki; Z Zhu; J Tzenova; Alain Lesage; Monique Séguin; Michel Tousignant; Nadia Chawky; Claude Vanier; Olivier Lipp; Martin Alda; Ridha Joober; Chawki Benkelfat; Guy Rouleau
TPH and suicidal behavior: a study in suicide completers.
Molecular psychiatry 2001;6(1):98-102.
2000: Sergiu C Blumen; Amos D Korczyn; Hugo Lavoie; S Medynski; Joab Chapman; A Asherov; Puiu Nisipeanu; Rivka Inzelberg; Ralph L Carasso; Jean-Pierre Bouchard; Fernando M S Tomé; Guy Rouleau; Bernard Brais
Oculopharyngeal MD among Bukhara Jews is due to a founder (GCG)9 mutation in the PABP2 gene.
Neurology 2000;55(9):1267-70.
2000: Vijayalakshmi Shanmugam; Patrick Dion; Daniel Rochefort; Josée Laganière; Bernard Brais; Guy Rouleau
PABP2 polyalanine tract expansion causes intranuclear inclusions in oculopharyngeal muscular dystrophy.
Annals of neurology 2000;48(5):798-802.
2000: Jérôme Lamartine; G Munhoz Essenfelder; Zoha Kibar; I Lanneluc; E Callouet; D Laoudj; Gilles Lemaître; C Hand; Susan J Hayflick; Jonathan (Jon) Zonana; S Antonarakis; Uppala Radhakrishna; D P Kelsell; A L Christianson; Amandine Pitaval; Vazken M Der Kaloustian; C Fraser; Claudine Blanchet-Bardon; Guy Rouleau; Gilles Waksman
Mutations in GJB6 cause hidrotic ectodermal dysplasia.
Nature genetics 2000;26(2):142-4.
2000: Anne Duffy; Gustavo Turecki; Paul Grof; Patrizia Cavazzoni; Eva Grof; Ridha Joober; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtĕchovský; P Zvolský; A Nilsson; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Carrie Robertson; Guy Rouleau; Martin Alda
Association and linkage studies of candidate genes involved in GABAergic neurotransmission in lithium-responsive bipolar disorder.
Journal of psychiatry & neuroscience : JPN 2000;25(4):353-8.
2000: Claudia Gaspar; M Jannatipour; Patrick Dion; Josée Laganière; Jorge Sequeiros; Bernard Brais; Guy Rouleau
CAG tract of MJD-1 may be prone to frameshifts causing polyalanine accumulation.
Human molecular genetics 2000;9(13):1957-66.
2000: Berge A Minassian; Leonarda Ianzano; M Meloche; Eva Andermann; Guy Rouleau; Antonio V Delgado-Escueta; Stephen W Scherer
Mutation spectrum and predicted function of laforin in Lafora's progressive myoclonus epilepsy.
Neurology 2000;55(3):341-6.
2000: S Hayes; Gustavo Turecki; Kateri Brisebois; Iscia Lopes-Cendes; Claudia Gaspar; Olaf Riess; Laura P W Ranum; Stef pulst; Guy Rouleau
CAG repeat length in RAI1 is associated with age at onset variability in spinocerebellar ataxia type 2 (SCA2).
Human molecular genetics 2000;9(12):1753-8.
2000: Jérôme Lamartine; Amandine Pitaval; Pascal Soularue; I Lanneluc; Gilles Lemaître; Zoha Kibar; Guy Rouleau; Gilles Waksman
A 1.5-Mb physical map of the hidrotic ectodermal dysplasia (Clouston syndrome) gene region on human chromosome 13q11.
Genomics 2000;67(2):232-6.
2000: Ridha Joober; André Toulouse; Chawki Benkelfat; Samarthji Lal; David Bloom; Alain Labelle; Pierre Lalonde; Gustavo Turecki; Guy Rouleau
DRD3 and DAT1 genes in schizophrenia: an association study.
Journal of psychiatric research 2000;34(4-5):285-91.
2000: Ridha Joober; Chawki Benkelfat; Samarthji Lal; David Bloom; Alain Labelle; Pierre Lalonde; Gustavo Turecki; R Rozen; Guy Rouleau
Association between the methylenetetrahydrofolate reductase 677C-->T missense mutation and schizophrenia.
Molecular psychiatry 2000;5(3):323-6.
2000: Zoha Kibar; Marie-Pierre Dubé; J Powell; C McCuaïg; Susan J Hayflick; Jonathan (Jon) Zonana; A Hovnanian; Uppala Radhakrishna; Stylianos Antonarakis; A Benohanian; A D Sheeran; M L Stephan; R Gosselin; D P Kelsell; A L Christianson; FC Fraser; Vazken M Der Kaloustian; Guy Rouleau
Clouston hidrotic ectodermal dysplasia (HED): genetic homogeneity, presence of a founder effect in the French Canadian population and fine genetic mapping.
European journal of human genetics : EJHG 2000;8(5):372-80.
2000: Martin Alda; Gustavo Turecki; Paul Grof; Patrizia Cavazzoni; Anne Duffy; Eva Grof; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtĕchovský; P Zvolský; Ridha Joober; A Nilsson; H Prochazka; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Guy Rouleau
Association and linkage studies of CRH and PENK genes in bipolar disorder: a collaborative IGSLI study.
American journal of medical genetics 2000;96(2):178-81.
2000: Gustavo Turecki; Martin Alda; Paul Grof; Ridha Joober; Ronald G Lafrenière; Patrizia Cavazzoni; Anne Duffy; Eva Grof; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtechovský; P Zvolský; A Nilsson; H Prochazka; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Guy Rouleau
Polyglutamine coding genes in bipolar disorder: lack of association with selected candidate loci.
Journal of affective disorders 2000;58(1):63-8.
2000: Jérôme Lamartine; D Laoudj; Claudine Blanchet-Bardon; Zoha Kibar; Pascal Soularue; V Ridoux; L Dubertret; Guy Rouleau; Gilles Waksman
Refined localization of the gene for Clouston syndrome (hidrotic ectodermal dysplasia) in a large French family.
The British journal of dermatology 2000;142(2):248-52.
2000: I Lopes-Cendes; I E Scheffer; S F Berkovic; M Rousseau; E Andermann; Guy Rouleau
A new locus for generalized epilepsy with febrile seizures plus maps to chromosome 2.
American journal of human genetics 2000;66(2):698-701.
1999: Ridha Joober; Chawki Benkelfat; André Toulouse; Ronald G Lafrenière; Samarthji Lal; S Ajroud; Gustavo Turecki; David Bloom; Alain Labelle; Pierre Lalonde; Martin Alda; Kenneth Morgan; Roberta Palmour; Guy Rouleau
Analysis of 14 CAG repeat-containing genes in schizophrenia.
American journal of medical genetics 1999;88(6):694-9.
1999: Gustavo Turecki; R Brière; Ken Dewar; T Antonetti; Alain Lesage; Monique Séguin; Nadia Chawky; Claude Vanier; Martin Alda; Ridha Joober; Chawki Benkelfat; Guy Rouleau
Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide.
The American journal of psychiatry 1999;156(9):1456-8.
1999: Gustavo Turecki; Paul Grof; Patrizia Cavazzoni; Anne Duffy; Eva Grof; R Martin; Ridha Joober; Guy Rouleau; Martin Alda
Lithium responsive bipolar disorder, unilineality, and chromosome 18: A linkage study.
American journal of medical genetics 1999;88(4):411-5.
1999: Sergiu C Blumen; Bernard Brais; Amos D Korczyn; S Medinsky; Joab Chapman; A Asherov; Puiu Nisipeanu; François Codère; Jean-Pierre Bouchard; M Fardeau; Fernando M S Tomé; Guy Rouleau
Homozygotes for oculopharyngeal muscular dystrophy have a severe form of the disease.
Annals of neurology 1999;46(1):115-8.
1999: William Camu; Jawad Khoris; Bruno Moulard; François Salachas; Valérie Briolotti; Guy Rouleau; Vincent Meininger
Genetics of familial ALS and consequences for diagnosis. French ALS Research Group.
Journal of the neurological sciences 1999;165 Suppl 1():S21-6.
1999: J S Parboosingh; Vincent Meininger; D McKenna-Yasek; R H Brown; Guy Rouleau
Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis.
Archives of neurology 1999;56(6):710-2.
1999: Gustavo Turecki; Martin Alda; Paul Grof; Ridha Joober; Patrizia Cavazzoni; Anne Duffy; Eva Grof; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtechovský; P Zvolský; A Nilsson; H Prochazka; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Guy Rouleau
Polyglutamine tracts: no evidence of a major role in bipolar disorder.
Molecular psychiatry 1999;4(3):220-1.
1999: Ridha Joober; Chawki Benkelfat; Kateri Brisebois; André Toulouse; Ronald G Lafrenière; Gustavo Turecki; Samarthji Lal; David Bloom; Alain Labelle; Pierre Lalonde; D Fortin; Martin Alda; Roberta Palmour; Guy Rouleau
Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia.
American journal of medical genetics 1999;88(2):154-7.
1999: Gustavo Turecki; Paul Grof; Patrizia Cavazzoni; Anne Duffy; Eva Grof; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtechovsky; Petr Zvolsky; Ridha Joober; A Nilsson; H Prochazka; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Guy Rouleau; Martin Alda
MAOA: association and linkage studies with lithium responsive bipolar disorder.
Psychiatric genetics 1999;9(1):13-6.
1999: Ridha Joober; Chawki Benkelfat; Kateri Brisebois; André Toulouse; Gustavo Turecki; Samarthji Lal; David Bloom; Alain Labelle; Pierre Lalonde; D Fortin; Martin Alda; Roberta Palmour; Guy Rouleau
T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability.
Journal of psychiatry & neuroscience : JPN 1999;24(2):141-6.
1999: Zoha Kibar; Ronald G Lafrenière; Aravinda Chakravarti; J C Wang; M Chevrette; Vazken M Der Kaloustian; Guy Rouleau
A radiation hybrid map of 48 loci including the clouston hidrotic ectodermal dysplasia locus in the pericentromeric region of chromosome 13q.
Genomics 1999;56(1):127-30.
1999: Patrícia Maciel; Claudia Gaspar; Laura Guimarães; Jun Goto; Iscia Lopes-Cendes; S Hayes; K Arvidsson; Adelaide Dias; Jorge Sequeiros; Alda Sousa; Guy Rouleau
Study of three intragenic polymorphisms in the Machado-Joseph disease gene (MJD1) in relation to genetic instability of the (CAG)n tract.
European journal of human genetics : EJHG 1999;7(2):147-56.
1999: M M Mezei; Ami Mankodi; Bernard Brais; Claude Marineau; Charles A Thornton; Guy Rouleau; George Karpati
Minimal expansion of the GCG repeat in the PABP2 gene does not predispose to sporadic inclusion body myositis.
Neurology 1999;52(3):669-70.
1999: Gustavo Turecki; Guy Rouleau; Martin Alda
Family density of alcoholism and linkage information in the analysis of the COGA data.
Genetic epidemiology 1999;17 Suppl 1():S361-6.
1999: Ridha Joober; Chawki Benkelfat; M Jannatipour; Gustavo Turecki; Samarthji Lal; J L Mandel; David Bloom; Pierre Lalonde; I Lopes-Cendes; D Fortin; Guy Rouleau
Polyglutamine-containing proteins in schizophrenia.
Molecular psychiatry 1999;4(1):53-7.
1998: Adrian M Siegel; Frederick Andermann; AmanPreet Badhwar; Guy Rouleau; M Dam; H C Hopf; J Dichgans; M Sturzenegger; N J Hopf; N Yasui; Frank Stepper; M Killer; J A Vanneste; Nicola Acciarri; P Drigo; J Christensen; V Braun; Dilek Könü; Eva Andermann
Anticipation in familial cavernous angioma: ascertainment bias or genetic cause.
Acta neurologica Scandinavica 1998;98(6):372-6.
1998: Adrian M Siegel; Eva Andermann; AmanPreet Badhwar; Guy Rouleau; G L Wolford; Frederick Andermann; K Hess
Anticipation in familial cavernous angioma: a study of 52 families from International Familial Cavernous Angioma Study. IFCAS Group.
Lancet 1998;352(9141):1676-7.
1998: Gustavo Turecki; Paul Grof; Patrizia Cavazzoni; Anne Duffy; Eva Grof; Bernd Ahrens; Anne Berghöfer; Bruno Müller-Oerlinghausen; M Dvoráková; E Libigerová; M Vojtechovský; P Zvolský; Ridha Joober; A Nilsson; H Prochazka; Rasmus W Licht; NA Rasmussen; M Schou; P Vestergaard; Anita Holzinger; C Schumann; K Thau; Guy Rouleau; Martin Alda
Evidence for a role of phospholipase C-gamma1 in the pathogenesis of bipolar disorder.
Molecular psychiatry 1998;3(6):534-8.
1998: Berge A Minassian; JR Lee; Jo-Anne Herbrick; J Huizenga; S Soder; Andrew Mungall; Carl Bruder; R Gardner; Chung Yan Fong; S Carpenter; Laura B Jardim; P Satishchandra; Eva Andermann; O Carter Snead; I Lopes-Cendes; Lap-Chee Tsui; Antonio V Delgado-Escueta; Guy Rouleau; Stephen W Scherer
Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy.
Nature genetics 1998;20(2):171-4.
1998: Ya-Gang Xie; Daniel Rochefort; Bernard Brais; Heidi C Howard; Fei-Yu Han; L P Gou; Patrícia Maciel; B T The; C Larsson; Guy Rouleau
Restriction map of a YAC and cosmid contig encompassing the oculopharyngeal muscular dystrophy candidate region on chromosome 14q11.2-q13.
Genomics 1998;52(2):201-4.
1998: Y Boukaftane; Jawad Khoris; Bruno Moulard; François Salachas; Vincent Meininger; A Malafosse; William Camu; Guy Rouleau
Identification of six novel SOD1 gene mutations in familial amyotrophic lateral sclerosis.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1998;25(3):192-6.
1998: Isabel Silveira; Paula Coutinho; Patrícia Maciel; Claudia Gaspar; S Hayes; Adelaide Dias; João Guimarães; Leal Loureiro; Jorge Sequeiros; Guy Rouleau
Analysis of SCA1, DRPLA, MJD, SCA2, and SCA6 CAG repeats in 48 Portuguese ataxia families.
American journal of medical genetics 1998;81(2):134-8.
1998: Bernard Brais; Jean-Pierre Bouchard; Ya-Gang Xie; Daniel Rochefort; N Chrétien; Fernando M S Tomé; Ronald G Lafrenière; Johanna M Rommens; Eiichiro Uyama; O Nohira; Sergiu C Blumen; Amos D Korczyn; Peter Heutink; Jean Mathieu; André Duranceau; François Codère; M Fardeau; Guy Rouleau; A D Korcyn
Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy.
Nature genetics 1998;18(2):164-7.
1997: Bernard Brais; Jean-Pierre Bouchard; F Gosselin; Ya-Gang Xie; M Fardeau; Fernando M S Tomé; Guy Rouleau
Using the full power of linkage analysis in 11 French Canadian families to fine map the oculopharyngeal muscular dystrophy gene.
Neuromuscular disorders : NMD 1997;7 Suppl 1():S70-4.
1997: Jean-Pierre Bouchard; Bernard Brais; Denis Brunet; P V Gould; Guy Rouleau
Recent studies on oculopharyngeal muscular dystrophy in Québec.
Neuromuscular disorders : NMD 1997;7 Suppl 1():S22-9.
1997: Ronald G Lafrenière; Zoha Kibar; Daniel Rochefort; Fei-Yu Han; Edward A Fon; Marie-Pierre Dubé; X Kang; S Baird; Robert G Korneluk; Johanna M Rommens; Guy Rouleau
Genomic structure of the human GT334 (EHOC-1) gene mapping to 21q22.3.
Gene 1997;198(1-2):313-21.
1997: H Shinotoh; B Thiessen; BJ Snow; S Hashimoto; Patrick M MacLeod; I Silveira; Guy Rouleau; Michael Schulzer; Donald B Calne
Fluorodopa and raclopride PET analysis of patients with Machado-Joseph disease.
Neurology 1997;49(4):1133-6.
1997: Iscia Lopes-Cendes; H G Teive; Maria E Calcagnotto; Jaderson Costa DaCosta; F Cardoso; E Viana; J A Maciel; J Radvany; W O Arruda; P C Trevisol-Bittencourt; Pedro Rosa-Neto; Isabel Silveira; Carlos Eduardo Steiner; W Pinto Júnior; A S Santos; Y Correa Neto; L C Werneck; A Q Araújo; G Carakushansky; L R Mello; Laura B Jardim; Guy Rouleau
Frequency of the different mutations causing spinocerebellar ataxia (SCA1, SCA2, MJD/SCA3 and DRPLA) in a large group of Brazilian patients.
Arquivos de neuro-psiquiatria 1997;55(3B):519-29.
1997: Jun Goto; Masahiko Watanabe; Y Ichikawa; S B Yee; N Ihara; K Endo; S Igarashi; Y Takiyama; Claudia Gaspar; Patrícia Maciel; Shoji Tsuji; Guy Rouleau; Ichiro Kanazawa
Machado-Joseph disease gene products carrying different carboxyl termini.
Neuroscience research 1997;28(4):373-7.
1997: J S Parboosingh; Denise A Figlewicz; A Krizus; Vincent Meininger; N A Azad; D S Newman; Guy Rouleau
Spinobulbar muscular atrophy can mimic ALS: the importance of genetic testing in male patients with atypical ALS.
Neurology 1997;49(2):568-72.
1997: Gustavo Turecki; Guy Rouleau; J Mari; Ridha Joober; Kenneth Morgan
Lack of association between bipolar disorder and tyrosine hydroxylase: a meta-analysis.
American journal of medical genetics 1997;74(4):348-52.
1997: Yvonne Robitaille; I Lopes-Cendes; M Becher; Guy Rouleau; A W Clark
The neuropathology of CAG repeat diseases: review and update of genetic and molecular features.
Brain pathology (Zurich, Switzerland) 1997;7(3):901-26.
1997: J O Claudio; R W Veneziale; A Sue Menko; Guy Rouleau
Expression of schwannomin in lens and Schwann cells.
Neuroreport 1997;8(8):2025-30.
1997: Gustavo Turecki; Guy Rouleau; Ridha Joober; J Mari; Kenneth Morgan
Schizophrenia and chromosome 6p.
American journal of medical genetics 1997;74(2):195-8.
1997: Ronald G Lafrenière; Daniel Rochefort; N Chrétien; Johanna M Rommens; J I Cochius; Reetta Kälviäinen; U Nousiainen; G Patry; K Farrell; B Söderfeldt; A Federico; B R Hale; O H Cossio; T Sørensen; M A Pouliot; T Kmiec; P Uldall; J Janszky; M R Pranzatelli; F Andermann; Eva Andermann; Guy Rouleau
Unstable insertion in the 5' flanking region of the cystatin B gene is the most common mutation in progressive myoclonus epilepsy type 1, EPM1.
Nature genetics 1997;15(3):298-302.
1997: Marie-Pierre Dubé; M A Mlodzienski; Zoha Kibar; Martin R Farlow; G Ebers; P Harper; E H Kolodny; Guy Rouleau; D A Figlewicz
Hereditary spastic paraplegia: LOD-score considerations for confirmation of linkage in a heterogeneous trait.
American journal of human genetics 1997;60(3):625-9.
1997: Gustavo Turecki; Guy Rouleau; Kenneth Morgan
Modeling the phenotype in parametric linkage analysis of bipolar disorder.
Genetic epidemiology 1997;14(6):687-91.
1996: Ronald G Lafrenière; Daniel Rochefort; Zoha Kibar; E A Fon; Fei-Yu Han; J Cochius; X Kang; S Baird; R G Korneluk; Eva Andermann; Johanna M Rommens; Guy Rouleau
Isolation and characterization of GT335, a novel human gene conserved in Escherichia coli and mapping to 21q22.3.
Genomics 1996;38(3):264-72.
1996: Ronald G Lafrenière; Daniel Rochefort; N Chrétien; C E Neville; R G Korneluk; L Zuo; Y Wei; J Lichter; Guy Rouleau
Isolation and genomic structure of a human homolog of the yeast periodic tryptophan protein 2 (PWP2) gene mapping to 21q22.3.
Genome research 1996;6(12):1216-26.
1996: D Watkins; M H Ruttledge; J Sarrazin; S Rangaratnam; M Poisson; J Y Delattre; Guy Rouleau
Loss of heterozygosity on chromosome 22 in human gliomas does not inactivate the neurofibromatosis type 2 gene.
Cancer genetics and cytogenetics 1996;92(1):73-8.
1996: Iscia Lopes-Cendes; Isabel Silveira; Patrícia Maciel; Claudia Gaspar; J Radvany; D Chitayat; R Babul; J Stewart; M Dolliver; Yvonne Robitaille; Guy Rouleau; Jorge Sequeiros
Limits of clinical assessment in the accurate diagnosis of Machado-Joseph disease.
Archives of neurology 1996;53(11):1168-74.
1996: Claudia Gaspar; Iscia Lopes-Cendes; Anita L DeStefano; Patrícia Maciel; Isabel Silveira; Paula Coutinho; P MacLeod; Jorge Sequeiros; Lindsay A Farrer; Guy Rouleau
Linkage disequilibrium analysis in Machado-Joseph disease patients of different ethnic origins.
Human genetics 1996;98(5):620-4.
1996: Patrizia Cavazzoni; Martin Alda; Gustavo Turecki; Guy Rouleau; Eva Grof; R Martin; Anne Duffy; Paul Grof
Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene.
Psychiatry research 1996;64(2):91-6.
1996: Iscia Lopes-Cendes; C E Steiner; Isabel Silveira; W Pinto Júnior; J A Maciel; Guy Rouleau
Clinical and molecular characteristics of a Brazilian family with spinocerebellar ataxia type 1.
Arquivos de neuro-psiquiatria 1996;54(3):412-8.
1996: M Lutchman; Guy Rouleau
Neurofibromatosis type 2: a new mechanism of tumor suppression.
Trends in neurosciences 1996;19(9):373-7.
1996: Gustavo Turecki; F Grand'Maison; B Lemieux; Guy Rouleau
Hyperekplexia and the alpha1 subunit glycine receptor gene (GLRA1)
Archives of neurology 1996;53(9):836-7.
1996: Iscia Lopes-Cendes; Patrícia Maciel; Stephen J Kish; Claudia Gaspar; Yvonne Robitaille; H B Clark; A H Koeppen; M Nance; L Schut; Isabel Silveira; Paula Coutinho; Jorge Sequeiros; Guy Rouleau
Somatic mosaicism in the central nervous system in spinocerebellar ataxia type 1 and Machado-Joseph disease.
Annals of neurology 1996;40(2):199-206.
1996: M Melanson; Colin Chalk; L Georgevich; K Fett; Y Lapierre; H Duong; J Richardson; Claude Marineau; Guy Rouleau
Varicella-zoster virus DNA in CSF and arteries in delayed contralateral hemiplegia: evidence for viral invasion of cerebral arteries.
Neurology 1996;47(2):569-70.
1996: M H Ruttledge; A A Andermann; CM Phelan; J O Claudio; Fei-Yu Han; N Chretien; S Rangaratnam; M MacCollin; P Short; D Parry; V Michels; V M Riccardi; R Weksberg; K Kitamura; J M Bradburn; B D Hall; P Propping; Guy Rouleau
Type of mutation in the neurofibromatosis type 2 gene (NF2) frequently determines severity of disease.
American journal of human genetics 1996;59(2):331-42.
1996: Gustavo Turecki; Martin Alda; Paul Grof; R Martin; Patrizia Cavazzoni; Anne Duffy; Patrícia Maciel; Guy Rouleau
No association between chromosome-18 markers and lithium-responsive affective disorders.
Psychiatry research 1996;63(1):17-23.
1996: John K Fink; T Heiman-Patterson; Thomas D Bird; Franca Cambi; Marie-Pierre Dubé; Denise A Figlewicz; J K Fink; Jonathan L Haines; Terry D Heiman-Patterson; A Hentati; Margaret Pericak-Vance; W Raskind; Guy Rouleau; Teepu Siddique
Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group.
Neurology 1996;46(6):1507-14.
1996: Gustavo Turecki; Guy Rouleau; J J Mari; K Morgan
A systematic evaluation of linkage studies in bipolar disorder.
Acta psychiatrica Scandinavica 1996;93(5):317-26.
1996: Ridha Joober; Guy Rouleau; E Fon; Samarthji Lal; Roberta Palmour; David Bloom; A Labelle; Chawki Benkelfat
Apolipoprotein E genotype in schizophrenia.
American journal of medical genetics 1996;67(2):235.
1996: Zoha Kibar; V M Der Kaloustian; B Brais; V Hani; F C Fraser; Guy Rouleau
The gene responsible for Clouston hidrotic ectodermal dysplasia maps to the pericentromeric region of chromosome 13q.
Human molecular genetics 1996;5(4):543-7.
1996: K Rooke; Denise A Figlewicz; F Y Han; Guy Rouleau
Analysis of the KSP repeat of the neurofilament heavy subunit in familiar amyotrophic lateral sclerosis.
Neurology 1996;46(3):789-90.
1996: Guy Rouleau; A W Clark; K Rooke; A Pramatarova; A Krizus; O Suchowersky; Jean-Pierre Julien; D Figlewicz
SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.
Annals of neurology 1996;39(1):128-31.
1996: Isabel Silveira; Iscia Lopes-Cendes; Stephen J Kish; Patrícia Maciel; Claudia Gaspar; Paula Coutinho; MI Botez; H Teive; Walter Oleschko Arruda; C E Steiner; W Pinto-Júnior; J A Maciel; S Jerin; GEORGE SACK; Eva Andermann; L Sudarsky; Roger Rosenberg; P MacLeod; D Chitayat; R Babul; Jorge Sequeiros; Guy Rouleau
Frequency of spinocerebellar ataxia type 1, dentatorubropallidoluysian atrophy, and Machado-Joseph disease mutations in a large group of spinocerebellar ataxia patients.
Neurology 1996;46(1):214-8.
1996: L K Casaubon; M Melanson; Iscia Lopes-Cendes; Claude Marineau; Eva Andermann; Frederick Andermann; J Weissenbach; C Prévost; J P Bouchard; J Mathieu; Guy Rouleau
The gene responsible for a severe form of peripheral neuropathy and agenesis of the corpus callosum maps to chromosome 15q.
American journal of human genetics 1996;58(1):28-34.
1995: E A Fon; J Sarrazin; C Meunier; J Alarcia; M I Shevell; Anne Philippe; Marion Leboyer; Guy Rouleau
Adenylosuccinate lyase (ADSL) and infantile autism: absence of previously reported point mutation.
American journal of medical genetics 1995;60(6):554-7.
1995: J O Claudio; M Lutchman; Guy Rouleau
Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene.
Neuroreport 1995;6(14):1942-6.
1995: Anita L DeStefano; Lindsay A Farrer; Patrícia Maciel; Claudia Gaspar; Guy Rouleau; Paula Coutinho; Jorge Sequeiros
Gender equality in Machado-Joseph disease.
Nature genetics 1995;11(2):118-9.
1995: M J Belliveau; M Lutchman; J O Claudio; Claude Marineau; Guy Rouleau
Schwannomin: new insights into this member of the band 4.1 superfamily.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1995;73(9-10):733-7.
1995: Ronald G Lafrenière; P J de Jong; Guy Rouleau
A 405-kb cosmid contig and HindIII restriction map of the progressive myoclonus epilepsy type 1 (EPM1) candidate region in 21q22.3.
Genomics 1995;29(1):288-90.
1995: S Demczuk; A Lévy; M Aubry; Marie-Françoise Croquette; N Philip; Marguerite Prieur; U Sauer; Patrice Bouvagnet; Guy Rouleau; Gilles Thomas
Excess of deletions of maternal origin in the DiGeorge/velo-cardio-facial syndromes. A study of 22 new patients and review of the literature.
Human genetics 1995;96(1):9-13.
1995: M Lutchman; Guy Rouleau
The neurofibromatosis type 2 gene product, schwannomin, suppresses growth of NIH 3T3 cells.
Cancer research 1995;55(11):2270-4.
1995: O Garofalo; Denise A Figlewicz; S M Thomas; R Butler; L Lebuis; Guy Rouleau; Vincent Meininger; P N Leigh
Superoxide dismutase activity in lymphoblastoid cells from motor neurone disease/amyotrophic lateral sclerosis (MND/ALS) patients.
Journal of the neurological sciences 1995;129 Suppl():90-2.
1995: S Demczuk; R Aledo; J Zucman; Olivier Delattre; C Desmaze; L Dauphinot; P Jalbert; Guy Rouleau; Gilles Thomas; Alain Aurias
Cloning of a balanced translocation breakpoint in the DiGeorge syndrome critical region and isolation of a novel potential adhesion receptor gene in its vicinity.
Human molecular genetics 1995;4(4):551-8.
1995: A Pramatarova; Denise A Figlewicz; A Krizus; Fei-Yu Han; Irène Ceballos-Picot; Annie Nicole; Michel DIB; Vincent Meininger; R H Brown; Guy Rouleau
Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis.
American journal of human genetics 1995;56(3):592-6.
1995: P Mérel; Khê Hoang-Xuan; M Sanson; EK Bijlsma; Guy Rouleau; Pierre Laurent-Puig; Stef pulst; M Baser; G Lenoir; J M Sterkers
Screening for germ-line mutations in the NF2 gene.
Genes, chromosomes & cancer 1995;12(2):117-27.
1995: E C Twist; L K Casaubon; M H Ruttledge; V S Rao; P M Macleod; J Radvany; Z Zhao; Roger Rosenberg; Lindsay A Farrer; Guy Rouleau
Machado Joseph disease maps to the same region of chromosome 14 as the spinocerebellar ataxia type 3 locus.
Journal of medical genetics 1995;32(1):25-31.
1995: J S Parboosingh; Guy Rouleau; V Meninger; Diane McKenna-Yasek; R H Brown; Denise A Figlewicz
Absence of mutations in the Mn superoxide dismutase or catalase genes in familial amyotrophic lateral sclerosis.
Neuromuscular disorders : NMD 1995;5(1):7-10.
1994: J Cochius; S Carpenter; Eva Andermann; Guy Rouleau; U Nousiainen; R Kalviainen; K Farrell; Frederick Andermann
Sweat gland vacuoles in Unverricht-Lundborg disease: a clue to diagnosis?
Neurology 1994;44(12):2372-5.
1994: A Pramatarova; J Goto; E Nanba; K Nakashima; K Takahashi; A Takagi; I Kanazawa; Denise A Figlewicz; Guy Rouleau
A two basepair deletion in the SOD 1 gene causes familial amyotrophic lateral sclerosis.
Human molecular genetics 1994;3(11):2061-2.
1994: Denise A Figlewicz; A Krizus; M G Martinoli; Vincent Meininger; Michel DIB; Guy Rouleau; Jean-Pierre Julien
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis.
Human molecular genetics 1994;3(10):1757-61.
1994: J O Claudio; Danielle Malo; Guy Rouleau
The mouse neurofibromatosis type 2 gene maps to chromosome 11.
Genomics 1994;21(2):437-9.
1994: Iscia Lopes-Cendes; Eva Andermann; E Attig; F Cendes; S Bosch; M Wagner; F Gerstenbrand; Frederick Andermann; Guy Rouleau
Confirmation of the SCA-2 locus as an alternative locus for dominantly inherited spinocerebellar ataxias and refinement of the candidate region.
American journal of human genetics 1994;54(5):774-81.
1994: Iscia Lopes-Cendes; Eva Andermann; Guy Rouleau
Evidence for the existence of a fourth dominantly inherited spinocerebellar ataxia locus.
Genomics 1994;21(1):270-4.
1994: E C Twist; Lindsay A Farrer; P M Macleod; J Radvany; S Chamberlain; Roger Rosenberg; Guy Rouleau
Machado Joseph disease is not an allele of the spinocerebellar ataxia 2 locus.
Human genetics 1994;93(3):335-8.
1994: D Watkins; F Dion; M Poisson; J Y Delattre; Guy Rouleau
Analysis of oncogene expression in primary human gliomas: evidence for increased expression of the ros oncogene.
Cancer genetics and cytogenetics 1994;72(2):130-6.
1994: Denise A Figlewicz; R M Garruto; A Krizus; R Yanagihara; Guy Rouleau
The Cu/Zn superoxide dismutase gene in ALS and parkinsonism-dementia of Guam.
Neuroreport 1994;5(5):557-60.
1994: J O Claudio; Claude Marineau; Guy Rouleau
The mouse homologue of the neurofibromatosis type 2 gene is highly conserved.
Human molecular genetics 1994;3(1):185-90.
1994: E C Twist; M H Ruttledge; M Rousseau; M Sanson; L Papi; P Merel; Olivier Delattre; Gilles Thomas; Guy Rouleau
The neurofibromatosis type 2 gene is inactivated in schwannomas.
Human molecular genetics 1994;3(1):147-51.
1994: D Watkins; Guy Rouleau
Genetics, prognosis and therapy of central nervous system tumors.
Cancer detection and prevention 1994;18(2):139-44.
1994: S Demczuk; C Desmaze; M Aikem; Marguerite Prieur; F Ledeist; M Sanson; Guy Rouleau; Gilles Thomas; Alain Aurias
Molecular cytogenetic analysis of a series of 23 DiGeorge syndrome patients by fluorescence in situ hybridization.
Annales de génétique 1994;37(2):60-5.
1993: Denise A Figlewicz; Guy Rouleau; A Krizus; Jean-Pierre Julien
Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene.
Gene 1993;132(2):297-300.
1993: M Aubry; S Demczuk; C Desmaze; M Aikem; Alain Aurias; J P Julien; Guy Rouleau
Isolation of a zinc finger gene consistently deleted in DiGeorge syndrome.
Human molecular genetics 1993;2(10):1583-7.
1993: M Sanson; F Zhang; S Demczuk; Olivier Delattre; P DeJong; Alain Aurias; Gilles Thomas; Guy Rouleau
Isolation and mapping of 45 NotI linking clones to chromosome 22.
Genomics 1993;17(3):776-9.
1993: Denise A Figlewicz; O Delattre; G Guellaen; A Krizus; G Thomas; J Zucman; Guy Rouleau
Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.
Genomics 1993;17(2):299-305.
1993: Guy Rouleau; P Merel; M Lutchman; M Sanson; J Zucman; Claude Marineau; Khê Hoang-Xuan; S Demczuk; C Desmaze; B Plougastel
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2.
Nature 1993;363(6429):515-21.
1993: J Goto; A Gnirke; N Khodr; E Kaufer; A Krizus; Denise A Figlewicz; Guy Rouleau
Dinucleotide repeat polymorphism at the D21S370 locus which flanks the PRGS (GARS)-PAIS (AIRS)-PGFT (GART) gene.
Human molecular genetics 1993;2(5):616.
1993: O Garofalo; Denise A Figlewicz; P N Leigh; J F Powell; Vincent Meininger; Michel DIB; Guy Rouleau
Androgen receptor gene polymorphisms in amyotrophic lateral sclerosis.
Neuromuscular disorders : NMD 1993;3(3):195-9.
1993: Claude Marineau; C Baron; Olivier Delattre; J Zucman; Gilles Thomas; Guy Rouleau
Dinucleotide repeat polymorphism at the D22S268 locus.
Human molecular genetics 1993;2(3):336.
1993: J Goto; Denise A Figlewicz; Jonathan L Haines; R H Brown; N Khodr; Guy Rouleau
The glycinamide ribonucleotide transformylase (GART) gene is not responsible for familial amyotrophic lateral sclerosis.
Neuromuscular disorders : NMD 1993;3(2):157-60.
1993: E A Fon; S Demczuk; Olivier Delattre; Gilles Thomas; Guy Rouleau
Mapping of the human adenylosuccinate lyase (ADSL) gene to chromosome 22q13.1-->q13.2.
Cytogenetics and cell genetics 1993;64(3-4):201-3.
1992: J Goto; Denise A Figlewicz; A Gnirke; N Khodr; A Krizus; Guy Rouleau
Dinucleotide repeat polymorphism at the D21S219 locus which flanks the GARS-AIRS-GART gene.
Human molecular genetics 1992;1(9):782.
1992: J Zucman; Olivier Delattre; C Desmaze; B Plougastel; I Joubert; T Melot; Martine Peter; P De Jong; Guy Rouleau; Alain Aurias
Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints.
Genes, chromosomes & cancer 1992;5(4):271-7.
1992: Olivier Delattre; J Zucman; B Plougastel; C Desmaze; T Melot; Martine Peter; Heinrich Kovar; I Joubert; P de Jong; Guy Rouleau
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours.
Nature 1992;359(6391):162-5.
1992: J Goto; F Tassone; S Demczuk; K Gardiner; Denise A Figlewicz; N Khodr; Guy Rouleau
Dinucleotide repeat polymorphism at the D21S65 locus.
Human molecular genetics 1992;1(5):350.
1992: W J Carson; J Radvany; Lindsay A Farrer; D Vincent; Roger Rosenberg; P M MacLeod; Guy Rouleau
The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1).
Genomics 1992;13(3):852-5.
1992: M Aubry; Claude Marineau; F R Zhang; L Zahed; D Figlewicz; Olivier Delattre; Gilles Thomas; P J de Jong; Jean-Pierre Julien; Guy Rouleau
Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2).
Genomics 1992;13(3):641-8.
1992: J Zucman; Olivier Delattre; C Desmaze; C Azambuja; Guy Rouleau; P De Jong; Alain Aurias; Gilles Thomas
Rapid isolation of cosmids from defined subregions by differential Alu-PCR hybridization on chromosome 22-specific library.
Genomics 1992;13(2):395-401.
1992: Claude Marineau; M Aubry; Jean-Pierre Julien; Guy Rouleau
Dinucleotide repeat polymorphism at the D22S264 locus.
Nucleic acids research 1992;20(6):1430.
1992: Claude Marineau; Guy Rouleau
Dinucleotide repeat polymorphism at the human CRYB2 gene locus (22q11.2).
Nucleic acids research 1992;20(6):1430.
1992: J Goto; Denise A Figlewicz; Claude Marineau; N Khodr; Guy Rouleau
Dinucleotide repeat polymorphism at the IGF2R locus.
Nucleic acids research 1992;20(4):923.
1992: D Watkins; Guy Rouleau
Oncogenes and glial tumors.
Revue neurologique 1992;148(6-7):402-7.
1991: J Goto; Denise A Figlewicz; M Lutchman; F Ruddle; Guy Rouleau
A PvuII RFLP at the HOX 1.4 homeobox locus (HOX1D).
Nucleic acids research 1991;19(13):3755.
1991: Olivier Delattre; C J Azambuja; Alain Aurias; J Zucman; Martine Peter; F Zhang; M C Hors-Cayla; Guy Rouleau; Gilles Thomas
Mapping of human chromosome 22 with a panel of somatic cell hybrids.
Genomics 1991;9(4):721-7.
1990: M Sanson; Olivier Delattre; Jérôme Couturier; J Philippon; J Cophignon; P Derome; Guy Rouleau; Gilles Thomas
Parental origin of chromosome 22 alleles lost in meningioma.
American journal of human genetics 1990;47(5):877-80.
1990: F R Zhang; Alain Aurias; Olivier Delattre; M H Stern; J Benitez; Guy Rouleau; Gilles Thomas
Mapping of human chromosome 22 by in situ hybridization.
Genomics 1990;7(3):319-24.
1990: Jérôme Couturier; Olivier Delattre; M Kujas; J Philippon; Martine Peter; Guy Rouleau; Alain Aurias; Gilles Thomas
Assessment of chromosome 22 anomalies in neurinomas by combined karyotype and RFLP analyses.
Cancer genetics and cytogenetics 1990;45(1):55-62.
1990: F R Zhang; Olivier Delattre; Guy Rouleau; Jérôme Couturier; Gilles Thomas; Alain Aurias
The neuroepithelioma breakpoint on chromosome 22 is proximal to the meningioma locus.
Genomics 1990;6(1):174-7.