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Philip Alfred Kern

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Michael Spencer; Resat Unal; R Grace Walton; Beibei Zhu; Akosua Adu; Marilyn Campbell; Rod Erfani; Brian S Finlin; Jonah Lee; Robert E McGehee; Andrew J Morris; Charlotte A Peterson; Lindsey R Shipp; Philip Alfred Kern
Omega-3 Fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance.
Brian S Finlin; Philip Alfred Kern; Robert E McGehee; Charlotte A Peterson; Catherine P Starnes; Aiwei Yao-Borengasser; Beibei Zhu; Angela M Bodles-Brakhop; Neda Rasouli
Regulation of small ubiquitin-like modifier-1, nuclear receptor coreceptor, histone deacetylase 3, and peroxisome proliferator-activated receptor-γ in human adipose tissue.
Michael Spencer; Resat Unal; Beibei Zhu; Robert E McGehee; Charlotte A Peterson; Neda Rasouli; Philip Alfred Kern
Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance.

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2013: Michael Spencer; Resat Unal; R Grace Walton; Beibei Zhu; Akosua Adu; Marilyn Campbell; Rod Erfani; Brian S Finlin; Jonah Lee; Robert E McGehee; Andrew J Morris; Charlotte A Peterson; Lindsey R Shipp; Philip Alfred Kern
Omega-3 Fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance.
Diabetes 2013;62(5):1709-17.
2012: Brian S Finlin; Philip Alfred Kern; Robert E McGehee; Charlotte A Peterson; Catherine P Starnes; Aiwei Yao-Borengasser; Beibei Zhu; Angela M Bodles-Brakhop; Neda Rasouli
Regulation of small ubiquitin-like modifier-1, nuclear receptor coreceptor, histone deacetylase 3, and peroxisome proliferator-activated receptor-γ in human adipose tissue.
Metabolic syndrome and related disorders 2012;10(4):312-7.
2011: Michael Spencer; Resat Unal; Beibei Zhu; Robert E McGehee; Charlotte A Peterson; Neda Rasouli; Philip Alfred Kern
Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance.
The Journal of clinical endocrinology and metabolism 2011;96(12):E1990-8.
2011: Aiwei Yao-Borengasser; Robert H Coker; Bounleut Phanavanh; Gouri Ranganathan; Neda Rasouli; Vijayalakshmi Varma; Philip Alfred Kern
Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone.
Metabolism: clinical and experimental 2011;60(7):1012-20.
2011: Haihong Zhang; Chenghui Xie; Horace Spencer; Chunlai Zuo; Masahiro Higuchi; Gouri Ranganathan; Philip Alfred Kern; Ming W Chou; Qin Huang; Bartosz Szczesny; Sankar Mitra; Amanda J Watson; Geoffrey P Margison; Chun-Yang Fan
Obesity and hepatosteatosis in mice with enhanced oxidative DNA damage processing in mitochondria.
The American journal of pathology 2011;178(4):1715-27.
2011: Steven C Elbein; Philip Alfred Kern; Neda Rasouli; Aiwei Yao-Borengasser; Neeraj K Sharma; Swapan K Das
Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin-resistant individuals matched for BMI.
Diabetes 2011;60(3):1019-29.
2010: Michael Spencer; Aiwei Yao-Borengasser; Resat Unal; Neda Rasouli; Catherine M Gurley; Beibei Zhu; Charlotte A Peterson; Philip Alfred Kern
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation.
American journal of physiology. Endocrinology and metabolism 2010;299(6):E1016-27.
2010: Latasha M Smith; Aiwei Yao-Borengasser; Tasha Starks; Mark Tripputi; Philip Alfred Kern; Neda Rasouli
Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle.
The Journal of clinical endocrinology and metabolism 2010;95(9):4441-8.
2010: Resat Unal; Aiwei Yao-Borengasser; Vijayalakshmi Varma; Neda Rasouli; Craig Labbate; Philip Alfred Kern; Gouri Ranganathan
Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone.
The Journal of clinical endocrinology and metabolism 2010;95(6):2993-3001.
2009: Robert H Coker; Rick H Williams; Sophie E Yeo; Patrick Kortebein; Donald L Bodenner; Philip Alfred Kern; William J Evans
The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.
The Journal of clinical endocrinology and metabolism 2009;94(11):4258-66.
2009: Neda Rasouli; Aiwei Yao-Borengasser; Vijayalakshmi Varma; Horace Spencer; Robert E McGehee; Charlotte A Peterson; Jawahar L Mehta; Philip Alfred Kern
Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(9):1328-35.
2009: Vijayalakshmi Varma; Aiwei Yao-Borengasser; Neda Rasouli; Greg T Nolen; Bounleut Phanavanh; Tasha Starks; Cathy Gurley; Pippa Simpson; Robert E McGehee; Philip Alfred Kern; Charlotte A Peterson
Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action.
American journal of physiology. Endocrinology and metabolism 2009;296(6):E1300-10.
2009: Anannya Banga; Resat Unal; Preeti Tripathi; Irina Pokrovskaya; Randall J Owens; Philip Alfred Kern; Gouri Ranganathan
Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids.
American journal of physiology. Endocrinology and metabolism 2009;296(3):E480-9.
2009: Robert H Coker; Rick H Williams; Sophie E Yeo; Patrick Kortebein; Don L Bodenner; Philip Alfred Kern; William J Evans
Visceral fat and adiponectin: associations with insulin resistance are tissue-specific in women.
Metabolic syndrome and related disorders 2009;7(1):61-7.
2008: Neda Rasouli; Philip Alfred Kern
Adipocytokines and the metabolic complications of obesity.
The Journal of clinical endocrinology and metabolism 2008;93(11 Suppl 1):S64-73.
2008: Neeraj K Sharma; Swapan K Das; Ashis K Mondal; Oksana G Hackney; Winston S Chu; Philip Alfred Kern; Neda Rasouli; Horace Spencer; Aiwei Yao-Borengasser; Steven C Elbein
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects.
The Journal of clinical endocrinology and metabolism 2008;93(11):4532-41.
2008: Aiwei Yao-Borengasser; Negah Rassouli; Vijayalakshmi Varma; Angela M Bodles; Neda Rasouli; Resat Unal; Bounleut Phanavanh; Gouri Ranganathan; Robert E McGehee; Philip Alfred Kern
Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness.
The Journal of clinical endocrinology and metabolism 2008;93(11):4431-9.
2008: Swapan K Das; Winston S Chu; Ashis K Mondal; Neeraj K Sharma; Philip Alfred Kern; Neda Rasouli; Steven C Elbein
Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines.
American journal of physiology. Endocrinology and metabolism 2008;295(2):E393-400.
2008: Resat Unal; Irina D Pokrovskaya; Preeti Tripathi; Brett P Monia; Philip Alfred Kern; Gouri Ranganathan
Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Calpha activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA.
The Biochemical journal 2008;413(2):315-22.
2008: Anannya Banga; Angela M Bodles; Neda Rasouli; Gouri Ranganathan; Philip Alfred Kern; Randall J Owens
Calcium is involved in formation of high molecular weight adiponectin.
Metabolic syndrome and related disorders 2008;6(2):103-11.
2008: Vijayalakshmi Varma; Aiwei Yao-Borengasser; Angela M Bodles; Neda Rasouli; Bounleut Phanavanh; Greg T Nolen; Emily M Kern; Radhakrishnan Nagarajan; Horace Spencer; Mi-Jeong Lee; Susan K Fried; Robert E McGehee; Charlotte A Peterson; Philip Alfred Kern
Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance.
Diabetes 2008;57(2):432-9.
2007: Steven C Elbein; Winston S Chu; Swapan Kumar Das; Aiwei Yao-Borengasser; Sandra J Hasstedt; Hua Wang; Neda Rasouli; Philip Alfred Kern
Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent.
Diabetologia 2007;50(8):1621-30.
2007: Aiwei Yao-Borengasser; Vijayalakshmi Varma; Angela M Bodles; Neda Rasouli; Bounleut Phanavanh; Mi-Jeong Lee; Tasha Starks; Leslie M Kern; Horace Spencer; Amir Adel Rashidi; Robert E McGehee; Susan K Fried; Philip Alfred Kern
Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone.
The Journal of clinical endocrinology and metabolism 2007;92(7):2590-7.
2007: Zhendong Liu; James Aronson; Elizabeth C Wahl; Lichu Liu; Daniel S Perrien; Philip Alfred Kern; John L Fowlkes; Kathryn M Thrailkill; Robert C Bunn; Gael E Cockrell; Robert A Skinner; Charles K Lumpkin
A novel rat model for the study of deficits in bone formation in type-2 diabetes.
Acta orthopaedica 2007;78(1):46-55.
2007: Vijayalakshmi Varma; Aiwei Yao-Borengasser; Neda Rasouli; Angela M Bodles; Bounleut Phanavanh; Mi-Jeong Lee; Tasha Starks; Leslie M Kern; Horace Spencer; Robert E McGehee; Susan K Fried; Philip Alfred Kern
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.
The Journal of clinical endocrinology and metabolism 2007;92(2):666-72.
2007: Neda Rasouli; Behzad Molavi; Steven C Elbein; Philip Alfred Kern
Ectopic fat accumulation and metabolic syndrome.
Diabetes, obesity & metabolism 2007;9(1):1-10.
2007: Neda Rasouli; Philip Alfred Kern; E Albert Reece; Steven C Elbein
Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes.
American journal of physiology. Endocrinology and metabolism 2007;292(1):E359-65.
2006: Nathan E Wolins; Benjamin K Quaynor; James R Skinner; Anatoly Tzekov; Michelle A Croce; Matthew C Gropler; Vijayalakshmi Varma; Aiwei Yao-Borengasser; Neda Rasouli; Philip Alfred Kern; Brian N Finck; Perry E Bickel
OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization.
Diabetes 2006;55(12):3418-28.
2006: Gouri Ranganathan; Resat Unal; Irina D Pokrovskaya; Aiwei Yao-Borengasser; Bounleut Phanavanh; Beata Lecka-Czernik; Neda Rasouli; Philip Alfred Kern
The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment.
Journal of lipid research 2006;47(11):2444-50.
2006: Angela M Bodles; Anannya Banga; Neda Rasouli; Fumiyo Ono; Philip Alfred Kern; Randall J Owens
Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes.
American journal of physiology. Endocrinology and metabolism 2006;291(5):E1100-5.
2006: Aiwei Yao-Borengasser; Neda Rasouli; Vijayalakshmi Varma; Leslie M Miles; Bounleut Phanavanh; Tasha Starks; Jack Phan; Horace Spencer; Robert E McGehee; Karen Reue; Philip Alfred Kern
Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation.
Diabetes 2006;55(10):2811-8.
2006: Behzad Molavi; Neda Rasouli; Philip Alfred Kern
The prevention and treatment of metabolic syndrome and high-risk obesity.
Current opinion in cardiology 2006;21(5):479-85.
2006: Angela M Bodles; Vijayalakshmi Varma; Aiwei Yao-Borengasser; Bounleut Phanavanh; Charlotte A Peterson; Robert E McGehee; Neda Rasouli; Martin Wabitsch; Philip Alfred Kern
Pioglitazone induces apoptosis of macrophages in human adipose tissue.
Journal of lipid research 2006;47(9):2080-8.
2006: Neda Rasouli; Aiwei Yao-Borengasser; Leslie M Miles; Steven C Elbein; Philip Alfred Kern
Increased plasma adiponectin in response to pioglitazone does not result from increased gene expression.
American journal of physiology. Endocrinology and metabolism 2006;290(1):E42-E46.
2005: Gouri Ranganathan; Irina D Pokrovskaya; Subramanian Ranganathan; Philip Alfred Kern
Role of A kinase anchor proteins in the tissue-specific regulation of lipoprotein lipase.
Molecular endocrinology (Baltimore, Md.) 2005;19(10):2527-34.
2005: Gina B Di Gregorio; Aiwei Yao-Borengasser; Neda Rasouli; Vijayalakshmi Varma; Tong Lu; Leslie M Miles; Gouri Ranganathan; Charlotte A Peterson; Robert E McGehee; Philip Alfred Kern
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone.
Diabetes 2005;54(8):2305-13.
2005: Neda Rasouli; Ulrika Raue; Leslie M Miles; Tong Lu; Gina B Di Gregorio; Steven C Elbein; Philip Alfred Kern
Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue.
American journal of physiology. Endocrinology and metabolism 2005;288(5):E930-4.
2004: Lili Yue; Neda Rasouli; Gouri Ranganathan; Philip Alfred Kern; Theodore Mazzone
Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression.
The Journal of biological chemistry 2004;279(46):47626-32.
2004: Gina B Di Gregorio; Rickard Westergren; Sven Enerback; Tong Lu; Philip Alfred Kern
Expression of FOXC2 in adipose and muscle and its association with whole body insulin sensitivity.
American journal of physiology. Endocrinology and metabolism 2004;287(4):E799-803.
2004: Philip Alfred Kern; Sufyan Said; William G Jackson; Joel Michalek
Insulin sensitivity following agent orange exposure in Vietnam veterans with high blood levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
The Journal of clinical endocrinology and metabolism 2004;89(9):4665-72.
2004: Gina B Di Gregorio; Lori Hensley; Tong Lu; Gouri Ranganathan; Philip Alfred Kern
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E182-7.
2004: Philip Alfred Kern; Gina B Di Gregorio; Tong Lu; Negah Rassouli; Gouri Ranganathan
Perilipin expression in human adipose tissue is elevated with obesity.
The Journal of clinical endocrinology and metabolism 2004;89(3):1352-8.
2004: Hua Wang; Winston S Chu; Tong Lu; Sandra J Hasstedt; Philip Alfred Kern; Steven C Elbein
Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.
American journal of physiology. Endocrinology and metabolism 2004;286(1):E1-7.
2003: Lori L Hensley; Gouri Ranganathan; Elke M Wagner; Brian D Wells; Joseph C Daniel; Diane Vu; Clay F Semenkovich; Rudolf Zechner; Philip Alfred Kern
Transgenic mice expressing lipoprotein lipase in adipose tissue. Absence of the proximal 3'-untranslated region causes translational upregulation.
The Journal of biological chemistry 2003;278(35):32702-9.
2003: Philip Alfred Kern; Gina B Di Gregorio; Tong Lu; Negah Rassouli; Gouri Ranganathan
Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression.
Diabetes 2003;52(7):1779-85.
2003: Vivian A Fonseca; Louis M Fink; Philip Alfred Kern
Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects.
Atherosclerosis 2003;167(1):105-9.
2002: Gouri Ranganathan; Dan C Phan; Irina D Pokrovskaya; Joan E McEwen; Li Lisa; Philip Alfred Kern
The translational regulation of lipoprotein lipase by epinephrine involves an RNA binding complex including the catalytic subunit of protein kinase A.
The Journal of biological chemistry 2002;277(45):43281-7.
2002: Gouri Ranganathan; Wei Song; Nicholas Dean; Brett P Monia; Steven W Barger; Philip Alfred Kern
Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes.
The Journal of biological chemistry 2002;277(41):38669-75.
2002: Philip Alfred Kern; Renata B Fishman; Wei Song; Aliza Dicker Brown; Vivian Fonseca
The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on oxidative enzymes in adipocytes and liver.
Toxicology 2002;171(2-3):117-25.
2002: Subramanian Ranganathan; Philip Alfred Kern
The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes.
The Journal of endocrinology 2002;172(1):155-62.
2002: Philip Alfred Kern; Aliza Dicker-Brown; Sufyan T Said; Richard Kennedy; Vivian A Fonseca
The stimulation of tumor necrosis factor and inhibition of glucose transport and lipoprotein lipase in adipose cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Metabolism: clinical and experimental 2002;51(1):65-8.
2001: Aliza Dicker-Brown; Vivian A Fonseca; Louis M Fink; Philip Alfred Kern
The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-beta-synthase: studies in hepatocytes.
Atherosclerosis 2001;158(2):297-301.
2001: Philip Alfred Kern; Subramanian Ranganathan; C Li; L Wood; Gouri Ranganathan
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance.
American journal of physiology. Endocrinology and metabolism 2001;280(5):E745-51.
2000: Gouri Ranganathan; Li Lisa; Philip Alfred Kern
The translational regulation of lipoprotein lipase in diabetic rats involves the 3'-untranslated region of the lipoprotein lipase mRNA.
The Journal of biological chemistry 2000;275(52):40986-91.
2000: M Cranmer; S Louie; Richard Kennedy; Philip Alfred Kern; Vivian A Fonseca
Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with hyperinsulinemia and insulin resistance.
Toxicological sciences : an official journal of the Society of Toxicology 2000;56(2):431-6.
2000: Vivian Fonseca; Aliza Dicker-Brown; S Ranganathan; Wei Song; R J Barnard; L Fink; Philip Alfred Kern
Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat.
Metabolism: clinical and experimental 2000;49(6):736-41.
1999: Philip Alfred Kern; R B Simsolo; M Fournier
Effect of weight loss on muscle fiber type, fiber size, capillarity, and succinate dehydrogenase activity in humans.
The Journal of clinical endocrinology and metabolism 1999;84(11):4185-90.
1999: Uwe Querfeld; M M Hoffmann; G Klaus; Frank Eifinger; M Ackerschott; Dietrich V Michalk; Philip Alfred Kern
Antagonistic effects of vitamin D and parathyroid hormone on lipoprotein lipase in cultured adipocytes.
Journal of the American Society of Nephrology : JASN 1999;10(10):2158-64.
1999: Gouri Ranganathan; R Kaakaji; Philip Alfred Kern
Role of protein kinase C in the translational regulation of lipoprotein lipase in adipocytes.
The Journal of biological chemistry 1999;274(13):9122-7.
1999: Gouri Ranganathan; Philip Alfred Kern
In vitro transcription and translation of lipoprotein lipase.
Methods in molecular biology (Clifton, N.J.) 1999;109():337-41.
1999: Gouri Ranganathan; Philip Alfred Kern
Techniques for the measurement of lipoprotein lipase messenger RNA.
Methods in molecular biology (Clifton, N.J.) 1999;109():329-35.
1998: Theodore P Ciaraldi; L Carter; Sunder Mudaliar; Philip Alfred Kern; R R Henry
Effects of tumor necrosis factor-alpha on glucose metabolism in cultured human muscle cells from nondiabetic and type 2 diabetic subjects.
Endocrinology 1998;139(12):4793-800.
1998: Subramanian Ranganathan; Philip Alfred Kern
Thiazolidinediones inhibit lipoprotein lipase activity in adipocytes.
The Journal of biological chemistry 1998;273(40):26117-22.
1998: Vivian A Fonseca; Sunder Mudaliar; B Schmidt; Louis M Fink; Philip Alfred Kern; R R Henry
Plasma homocysteine concentrations are regulated by acute hyperinsulinemia in nondiabetic but not type 2 diabetic subjects.
Metabolism: clinical and experimental 1998;47(6):686-9.
1998: Subramanian Ranganathan; Theodore P Ciaraldi; R R Henry; Sunder Mudaliar; Philip Alfred Kern
Lack of effect of leptin on glucose transport, lipoprotein lipase, and insulin action in adipose and muscle cells.
Endocrinology 1998;139(5):2509-13.
1998: S Ranganathan; M Maffei; Philip Alfred Kern
Adipose tissue ob mRNA expression in humans: discordance with plasma leptin and relationship with adipose TNFalpha expression.
Journal of lipid research 1998;39(4):724-30.
1997: Philip Alfred Kern
A prudent and practical approach to the treatment of obesity.
The Journal of the Arkansas Medical Society 1997;94(5):191-7.
1997: Philip Alfred Kern
Potential role of TNFalpha and lipoprotein lipase as candidate genes for obesity.
The Journal of nutrition 1997;127(9):1917S-1922S.
1997: P Maheux; S Azhar; Philip Alfred Kern; Yii-Der I Chen; G M Reuven
Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase.
Diabetologia 1997;40(7):850-8.
1997: Gouri Ranganathan; D Vu; Philip Alfred Kern
Translational regulation of lipoprotein lipase by epinephrine involves a trans-acting binding protein interacting with the 3' untranslated region.
The Journal of biological chemistry 1997;272(4):2515-9.
1997: Sungshin Y Choi; L Pang; Philip Alfred Kern; H J Kayden; L K Curtiss; TM Vanni-Reyes; Ira J Goldberg
Dissociation of LPL and LDL: effects of lipoproteins and anti-apoB antibodies.
Journal of lipid research 1997;38(1):77-85.
1996: Philip Alfred Kern; Gouri Ranganathan; Ada Yukht; J M Ong; R C Davis
Translational regulation of lipoprotein lipase by thyroid hormone is via a cytoplasmic repressor that interacts with the 3' untranslated region.
Journal of lipid research 1996;37(11):2332-40.
1996: D Vu; J M Ong; Thomas Landes Clemens; Philip Alfred Kern
1,25-Dihydroxyvitamin D induces lipoprotein lipase expression in 3T3-L1 cells in association with adipocyte differentiation.
Endocrinology 1996;137(5):1540-4.
1996: Mehrnoosh Saghizadeh; J M Ong; W T Garvey; R R Henry; Philip Alfred Kern
The expression of TNF alpha by human muscle. Relationship to insulin resistance.
The Journal of clinical investigation 1996;97(4):1111-6.
1995: J M Ong; R B Simsolo; Mehrnoosh Saghizadeh; J W Goers; Philip Alfred Kern
Effects of exercise training and feeding on lipoprotein lipase gene expression in adipose tissue, heart, and skeletal muscle of the rat.
Metabolism: clinical and experimental 1995;44(12):1596-605.
1995: Ada Yukht; R C Davis; J M Ong; Gouri Ranganathan; Philip Alfred Kern
Regulation of lipoprotein lipase translation by epinephrine in 3T3-L1 cells. Importance of the 3' untranslated region.
The Journal of clinical investigation 1995;96(5):2438-44.
1995: R B Simsolo; S Ezzat; J M Ong; Mehrnoosh Saghizadeh; Philip Alfred Kern
Effects of acromegaly treatment and growth hormone on adipose tissue lipoprotein lipase.
The Journal of clinical endocrinology and metabolism 1995;80(11):3233-8.
1995: Philip Alfred Kern; Mehrnoosh Saghizadeh; J M Ong; R J Bosch; Richard Deem; R B Simsolo
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
The Journal of clinical investigation 1995;95(5):2111-9.
1995: Gouri Ranganathan; J M Ong; Ada Yukht; Mehrnoosh Saghizadeh; R B Simsolo; A Pauer; Philip Alfred Kern
Tissue-specific expression of human lipoprotein lipase. Effect of the 3'-untranslated region on translation.
The Journal of biological chemistry 1995;270(13):7149-55.
1994: J M Ong; R B Simsolo; Mehrnoosh Saghizadeh; A Pauer; Philip Alfred Kern
Expression of lipoprotein lipase in rat muscle: regulation by feeding and hypothyroidism.
Journal of lipid research 1994;35(9):1542-51.
1994: B G Slavin; J M Ong; Philip Alfred Kern
Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes.
Journal of lipid research 1994;35(9):1535-41.
1994: Philip Alfred Kern; L Trozzolino; G Wolfe; L Purdy
Combined use of behavior modification and very low-calorie diet in weight loss and weight maintenance.
The American journal of the medical sciences 1994;307(5):325-8.
1994: N Venkatesan; Mayer B Davidson; R B Simsolo; Philip Alfred Kern
Phenobarbital treatment enhances insulin-mediated glucose metabolism and improves lipid metabolism in the diabetic rat.
Metabolism: clinical and experimental 1994;43(3):348-56.
1993: R B Simsolo; J M Ong; Philip Alfred Kern
Effect of gemfibrozil on adipose tissue and muscle lipoprotein lipase.
Metabolism: clinical and experimental 1993;42(11):1486-91.
1993: R B Simsolo; J M Ong; Philip Alfred Kern
The regulation of adipose tissue and muscle lipoprotein lipase in runners by detraining.
The Journal of clinical investigation 1993;92(5):2124-30.
1992: R B Simsolo; J M Ong; Philip Alfred Kern
Characterization of lipoprotein lipase activity, secretion, and degradation at different sites of post-translational processing in primary cultures of rat adipocytes.
Journal of lipid research 1992;33(12):1777-84.
1992: J M Ong; R B Simsolo; B Saffari; Philip Alfred Kern
The regulation of lipoprotein lipase gene expression by dexamethasone in isolated rat adipocytes.
Endocrinology 1992;130(4):2310-6.
1992: B Saffari; J M Ong; Philip Alfred Kern
Regulation of adipose tissue lipoprotein lipase gene expression by thyroid hormone in rats.
Journal of lipid research 1992;33(2):241-9.
1992: J M Ong; B Saffari; R B Simsolo; Philip Alfred Kern
Epinephrine inhibits lipoprotein lipase gene expression in rat adipocytes through multiple steps in posttranscriptional processing.
Molecular endocrinology (Baltimore, Md.) 1992;6(1):61-9.
1992: R B Simsolo; J M Ong; B Saffari; Philip Alfred Kern
Effect of improved diabetes control on the expression of lipoprotein lipase in human adipose tissue.
Journal of lipid research 1992;33(1):89-95.
1990: Daniel J Wallace; A L Metzger; Vera J Stecher; B A Turnbull; Philip Alfred Kern
Cholesterol-lowering effect of hydroxychloroquine in patients with rheumatic disease: reversal of deleterious effects of steroids on lipids.
The American journal of medicine 1990;89(3):322-6.
1990: Uwe Querfeld; J M Ong; J Prehn; J Carty; B Saffari; S C Jordan; Philip Alfred Kern
Effects of cytokines on the production of lipoprotein lipase in cultured human macrophages.
Journal of lipid research 1990;31(8):1379-86.
1990: Philip Alfred Kern; J M Ong; B Saffari; J Carty
The effects of weight loss on the activity and expression of adipose-tissue lipoprotein lipase in very obese humans.
The New England journal of medicine 1990;322(15):1053-9.
1990: Philip Alfred Kern; R A Martin; J Carty; I J Goldberg; J M Ong
Identification of lipoprotein lipase immunoreactive protein in pre- and postheparin plasma from normal subjects and patients with type I hyperlipoproteinemia.
Journal of lipid research 1990;31(1):17-26.
1989: A Knedler; R H Eckel; Philip Alfred Kern; R G Ham
Microvascular endothelial cell cultures from human omental adipose tissue.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(10):863-4.
1989: J M Ong; Philip Alfred Kern
Effect of feeding and obesity on lipoprotein lipase activity, immunoreactive protein, and messenger RNA levels in human adipose tissue.
The Journal of clinical investigation 1989;84(1):305-11.
1989: Philip Alfred Kern; M E Svoboda; R H Eckel; Judson Vanwyk
Insulinlike growth factor action and production in adipocytes and endothelial cells from human adipose tissue.
Diabetes 1989;38(6):710-7.
1989: J M Ong; Philip Alfred Kern
The role of glucose and glycosylation in the regulation of lipoprotein lipase synthesis and secretion in rat adipocytes.
The Journal of biological chemistry 1989;264(6):3177-82.
1988: J M Ong; T G Kirchgessner; Michael C Schotz; Philip Alfred Kern
Insulin increases the synthetic rate and messenger RNA level of lipoprotein lipase in isolated rat adipocytes.
The Journal of biological chemistry 1988;263(26):12933-8.
1988: Philip Alfred Kern
Recombinant human tumor necrosis factor does not inhibit lipoprotein lipase in primary cultures of isolated human adipocytes.
Journal of lipid research 1988;29(7):909-14.
1988: Philip Alfred Kern; J M Ong; J W Goers; M E Pedersen
Regulation of lipoprotein lipase immunoreactive mass in isolated human adipocytes.
The Journal of clinical investigation 1988;81(2):398-406.
1987: Philip Alfred Kern; A Mandic; R H Eckel
Regulation of lipoprotein lipase by glucose in primary cultures of isolated human adipocytes. Relevance to hypertriglyceridemia of diabetes.
Diabetes 1987;36(11):1238-45.
1987: J W Goers; M E Pedersen; Philip Alfred Kern; J Ong; Michael C Schotz
An enzyme-linked immunoassay for lipoprotein lipase.
Analytical biochemistry 1987;166(1):27-35.
1987: Philip Alfred Kern
Lipid disorders in diabetes mellitus.
The Mount Sinai journal of medicine, New York 1987;54(3):245-52.
1986: Philip Alfred Kern; R J Robbins; D Bichet; T Berl; Joseph G Verbalis
Syndrome of inappropriate antidiuresis in the absence of arginine vasopressin.
The Journal of clinical endocrinology and metabolism 1986;62(1):148-52.
1985: Philip Alfred Kern; S Marshall; R H Eckel
Regulation of lipoprotein lipase in primary cultures of isolated human adipocytes.
The Journal of clinical investigation 1985;75(1):199-208.
1984: R J Robbins; Philip Alfred Kern; T L Thompson
Interactions between thioridazine and bromocriptine in a patient with a prolactin-secreting pituitary adenoma.
The American journal of medicine 1984;76(5):921-3.
1984: Philip Alfred Kern; R H Eckel
Absence of lipoprotein lipase in cultured human adipose stromal cells.
Arteriosclerosis (Dallas, Tex.) 1984;4(3):232-7.
1984: R H Eckel; J E Prasad; Philip Alfred Kern; S Marshall
Insulin regulation of lipoprotein lipase in cultured isolated rat adipocytes.
Endocrinology 1984;114(5):1665-71.
1983: Philip Alfred Kern; A Knedler; R H Eckel
Isolation and culture of microvascular endothelium from human adipose tissue.
The Journal of clinical investigation 1983;71(6):1822-9.
1983: Philip Alfred Kern; R J Robbins
Unilateral toxic multicystic goiter.
Archives of internal medicine 1983;143(4):834-5.