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Gregory Charles Ippolito

Research Profile

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Jian Xu; Bryan G Chong; Benjamin L Ebert; Erica B Esrick; Yuko Fujiwara; Gregory Charles Ippolito; Cong Peng; Vijay G Sankaran; Zhen Shao; Philip W Tucker; Stuart H Orkin
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Gülşen Sürmeli; Philip W Tucker; Turgay Akay; Gregory Charles Ippolito; Thomas M Jessell
Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template.
Xiaoming Feng; Gregory Charles Ippolito; Lifeng Tian; Karla Wiehagen; Soyoung Oh; Arivazhagan Sambandam; Jessica Willen; Ralph M Bunte; Shanna D Maika; June V Harriss; Andrew J Caton; Avinash Bhandoola; Philip W Tucker; Hui Hu
Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.

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All Publications

2011: Jian Xu; Bryan G Chong; Benjamin L Ebert; Erica B Esrick; Yuko Fujiwara; Gregory Charles Ippolito; Cong Peng; Vijay G Sankaran; Zhen Shao; Philip W Tucker; Stuart H Orkin
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Science (New York, N.Y.) 2011;334(6058):993-6.
2011: Gülşen Sürmeli; Philip W Tucker; Turgay Akay; Gregory Charles Ippolito; Thomas M Jessell
Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template.
Cell 2011;147(3):653-65.
2010: Xiaoming Feng; Gregory Charles Ippolito; Lifeng Tian; Karla Wiehagen; Soyoung Oh; Arivazhagan Sambandam; Jessica Willen; Ralph M Bunte; Shanna D Maika; June V Harriss; Andrew J Caton; Avinash Bhandoola; Philip W Tucker; Hui Hu
Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.
Blood 2010;115(3):510-8.
2009: Vijay G Sankaran; Jian Xu; Tobias Ragoczy; Gregory Charles Ippolito; Carl R Walkley; Shanna D Maika; Yuko Fujiwara; Masafumi Ito; Mark Groudine; MA Bender; Philip W Tucker; Stuart H Orkin
Developmental and species-divergent globin switching are driven by BCL11A.
Nature 2009;460(7259):1093-7.
2009: Christian Schmidt; Dongkyoon Kim; Gregory Charles Ippolito; Hassan R Naqvi; Loren Probst; Shawn Mathur; German Rosas-Acosta; Van G Wilson; Athenia L Oldham; Martin Poenie; Carol F Webb; Philip W Tucker
Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.
The EMBO journal 2009;28(6):711-24.
2008: Michael Zemlin; Robert L Schelonka; Gregory Charles Ippolito; Cosima Zemlin; Yingxin Zhuang; G Larry Gartland; Lars Nitschke; Jukka Pelkonen; Klaus Rajewsky; Harry Schroeder
Regulation of repertoire development through genetic control of DH reading frame preference.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8416-24.
2008: Robert L Schelonka; Michael Zemlin; Ryoki Kobayashi; Gregory Charles Ippolito; Yingxin Zhuang; G Larry Gartland; Alexander Szalai; Kohtaro Fujihashi; Klaus Rajewsky; Harry Schroeder
Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8409-15.
2007: Henry B Koon; Gregory Charles Ippolito; Alison H Banham; Philip W Tucker
FOXP1: a potential therapeutic target in cancer.
Expert opinion on therapeutic targets 2007;11(7):955-65.
2007: Danjuan Lin; Gregory Charles Ippolito; Rui-Ting Zong; James Bryant; Janet Koslovsky; Philip Tucker
Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer.
Molecular cancer 2007;6():23.
2006: Karen Pulford; Alison H Banham; L Lyne; M Jones; Gregory Charles Ippolito; H Liu; Philip W Tucker; Giovanna Roncador; Elena Lucas; S Ashe; L Stockwin; Renata Walewska; Lorraine Karran; Randy D Gascoyne; David Y Mason; Martin J S Dyer
The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells.
Leukemia 2006;20(8):1439-41.
2006: Gregory Charles Ippolito; Robert L Schelonka; Michael Zemlin; Ivaylo I Ivanov; Ryoki Kobayashi; Cosima Zemlin; G Larry Gartland; Lars Nitschke; Jukka Pelkonen; Kohtaro Fujihashi; Klaus Rajewsky; Harry Schroeder
Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.
The Journal of experimental medicine 2006;203(6):1567-78.
2006: Hui Liu; Gregory Charles Ippolito; Jason K Wall; Teresa Niu; Loren Probst; Baeck-Seung Lee; Karen Pulford; Alison H Banham; Luke Stockwin; Arthur L Shaffer; Louis M Staudt; Chhaya Das; Martin J S Dyer; Philip W Tucker
Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells.
Molecular cancer 2006;5():18.
2005: Robert L Schelonka; Ivaylo I Ivanov; David H Jung; Gregory Charles Ippolito; Lars Nitschke; Yingxin Zhuang; G Larry Gartland; Jukka Pelkonen; Frederick W Alt; Klaus Rajewsky; Harry Schroeder
A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6624-32.
2005: Michael Zemlin; Gregory Charles Ippolito; Cosima Zemlin; Jason Link; Marc Monestier; Harry Schroeder
Adult lupus-prone MRL/MpJ2+ mice express a primary antibody repertoire that differs in CDR-H3 length distribution and hydrophobicity from that expressed in the C3H parental strain.
Molecular immunology 2005;42(7):789-98.
2005: Gregory Charles Ippolito; Christian Schmidt; Chhaya Das; Philip W Tucker
Towards open access.
Molecular cancer 2005;4(1):20.
2003: Gregory Charles Ippolito; Jukka Pelkonen; Lars Nitschke; Klaus Rajewsky; Harry Schroeder
Antibody repertoire in a mouse with a simplified D(H) locus: the D-limited mouse.
Annals of the New York Academy of Sciences 2003;987():262-5.
2001: Yi Xu; M Ma; Gregory Charles Ippolito; Harry Schroeder; M C Carroll; John E Volanakis
Complement activation in factor D-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14577-82.
1998: Harry Schroeder; Gregory Charles Ippolito; S Shiokawa
Regulation of the antibody repertoire through control of HCDR3 diversity.
Vaccine 1998;16(14-15):1383-90.