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Juul Wijnen

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Setareh Moghadasi; N Hofland; Frans B L Hogervorst; Maaike P G Vreeswijk; Juul Wijnen; Joyce N Wouts; Christi J van Asperen
Variants of uncertain significance in BRCA1 and BRCA2 assessment of in silico analysis and a proposal for communication in genetic counselling.
Florentine S Hilbers; Nicoline Hoogerbrugge; Paul A James; Siranoush Manoukian; Kenneth Offit; Jan C Oosterwijk; Paolo Peterlongo; Paolo Radice; Sohela Shah; Ella R Thompson; Alison H Trainer; Christi J van Asperen; Xianshu Wang; Juul Wijnen; Javier Benitez; Ian G Campbell; Fabio Capra; Margriet J Collee; Fergus J Couch; Irene Feroce; Javier Gracia; Lucia Guidugli; Peter Devilee
Rare variants in XRCC2 as breast cancer susceptibility alleles.
Amanda B Spurdle; Dominique Stoppa-Lyonnet; Mads Thomassen; Gail Tomlinson; Nadine Tung; Theo A van Os; Senno Verhoef; Carole Verny-Pierre; Fei Wan; Xianshu Wang; Jeff Weitzel; Juul Wijnen; Matti A Rookus; Christina G Selkirk; Christian F Singer; Olga Sinilnikova; Olga M Sinilnikova; Antonis C Antoniou; Margreet G E M Ausems; Laure Barjhoux; Jonathan Beesley; Muriel Belotti; Marinus J Blok; Joanne L Blum; Bruno Buecher; Tomasz Byrski; Ma Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Carol Chu; Marie-Agnès Collonge-Rame; Don Conroy; Margaret Cook; Fergus J Couch; Mary Daly; Rosemarie Davidson; Peter Devilee; Susan Domchek; Anne-Catharine Dressler; Hélène Dreyfus; Francine Durocher; Douglas F Easton; Diana Eccles; Ros Eeles; Hans Ehrencrona; D Gareth Evans; Debra Frost; Patricia Anne Ganz; Judy Garber; Daphne Gschwantler-Kaulich; Sue Healey; Tuomas Heikkinen; Nicoline Hoogerbrugge; Tomasz Huzarski; Claudine Isaacs; Louise Izatt; Anna Jakubowska; Helena Jernström; Per Karlsson; Mieke Kriege; Fiona Lalloo; Christine Lasset; Annelie Liljegren; Noralane M Lindor; Jan Lubinski; Henry Lynch; Louise Marquart; Sylvie Mazoyer; Lesley McGuffog; Hanne E J Meijers-Heijboer; Kate Nathanson; Susan Neuhausen; Heli Nevanlinna; Clare T Oliver; Olufunmilayo I Olopade; Susan Peock; Pascal Pujol; Timothy R Rebbeck
Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.

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2013: Setareh Moghadasi; N Hofland; Frans B L Hogervorst; Maaike P G Vreeswijk; Juul Wijnen; Joyce N Wouts; Christi J van Asperen
Variants of uncertain significance in BRCA1 and BRCA2 assessment of in silico analysis and a proposal for communication in genetic counselling.
Journal of medical genetics 2013;50(2):74-9.
2012: Florentine S Hilbers; Nicoline Hoogerbrugge; Paul A James; Siranoush Manoukian; Kenneth Offit; Jan C Oosterwijk; Paolo Peterlongo; Paolo Radice; Sohela Shah; Ella R Thompson; Alison H Trainer; Christi J van Asperen; Xianshu Wang; Juul Wijnen; Javier Benitez; Ian G Campbell; Fabio Capra; Margriet J Collee; Fergus J Couch; Irene Feroce; Javier Gracia; Lucia Guidugli; Peter Devilee
Rare variants in XRCC2 as breast cancer susceptibility alleles.
Journal of medical genetics 2012;49(10):618-20.
2011: Amanda B Spurdle; Dominique Stoppa-Lyonnet; Mads Thomassen; Gail Tomlinson; Nadine Tung; Theo A van Os; Senno Verhoef; Carole Verny-Pierre; Fei Wan; Xianshu Wang; Jeff Weitzel; Juul Wijnen; Matti A Rookus; Christina G Selkirk; Christian F Singer; Olga Sinilnikova; Olga M Sinilnikova; Antonis C Antoniou; Margreet G E M Ausems; Laure Barjhoux; Jonathan Beesley; Muriel Belotti; Marinus J Blok; Joanne L Blum; Bruno Buecher; Tomasz Byrski; Ma Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Carol Chu; Marie-Agnès Collonge-Rame; Don Conroy; Margaret Cook; Fergus J Couch; Mary Daly; Rosemarie Davidson; Peter Devilee; Susan Domchek; Anne-Catharine Dressler; Hélène Dreyfus; Francine Durocher; Douglas F Easton; Diana Eccles; Ros Eeles; Hans Ehrencrona; D Gareth Evans; Debra Frost; Patricia Anne Ganz; Judy Garber; Daphne Gschwantler-Kaulich; Sue Healey; Tuomas Heikkinen; Nicoline Hoogerbrugge; Tomasz Huzarski; Claudine Isaacs; Louise Izatt; Anna Jakubowska; Helena Jernström; Per Karlsson; Mieke Kriege; Fiona Lalloo; Christine Lasset; Annelie Liljegren; Noralane M Lindor; Jan Lubinski; Henry Lynch; Louise Marquart; Sylvie Mazoyer; Lesley McGuffog; Hanne E J Meijers-Heijboer; Kate Nathanson; Susan Neuhausen; Heli Nevanlinna; Clare T Oliver; Olufunmilayo I Olopade; Susan Peock; Pascal Pujol; Timothy R Rebbeck
Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(5):1032-8.
2011: Virginia Alonso-Espinaco; María Dolores Giráldez; Carlos Trujillo; Heleen van der Klift; Jenifer Muñoz; Francesc Balaguer; Teresa Ocaña; Irene Madrigal; Angela M Jones; M Magdalena Echeverry; Alejandro Velez; Ian Tomlinson; Montserrat Milà; Juul Wijnen; Luis Carvajal Carmona; Antoni Castells; Sergi Castellví-Bel
Novel MLH1 duplication identified in Colombian families with Lynch syndrome.
Genetics in medicine : official journal of the American College of Medical Genetics 2011;13(2):155-60.
2010: Marijke Wasielewski; Astrid A Out; Joyce Vermeulen; Maartje Nielsen; Ans van den Ouweland; Carli Tops; Juul Wijnen; Hans F A Vasen; Janneke Weiss; Jan G M Klijn; Peter Devilee; Frederik J Hes; Mieke Schutte
Increased MUTYH mutation frequency among Dutch families with breast cancer and colorectal cancer.
Breast cancer research and treatment 2010;124(3):635-41.
2010: Astrid A Out; Carli M J Tops; Maartje Nielsen; Janneke Weiss; Ivonne J H M van Minderhout; Ivo F A C Fokkema; Marie-Pierre Buisine; Kathleen Claes; Chrystelle Colas; Riccardo Fodde; Florentia Fostira; Patrick F Franken; Mette Gaustadnes; Karl Heinimann; Shirley V Hodgson; Frans B L Hogervorst; Elke Holinski-Feder; Kristina Lagerstedt-Robinson; Sylviane Olschwang; Ans M W van den Ouweland; Egbert J W Redeker; Rodney J Scott; Bruno Vankeirsbilck; Rikke Veggerby Grønlund; Juul Wijnen; Friedrik P Wikman; Stefan Aretz; Julian R Sampson; Peter Devilee; Johan T den Dunnen; Frederik J Hes
Leiden Open Variation Database of the MUTYH gene.
Human mutation 2010;31(11):1205-15.
2010: Arjan C Lankester; Marc Bierings; Elisabeth R van Wering; A J M Wijkhuijs; R A de Weger; Juul Wijnen; J M Vossen; B Versluys; R Maarten Egeler; M J D van Tol; H Putter; Tom Révész; J J M van Dongen; V H J van der Velden; Marco W Schilham
Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation.
Leukemia 2010;24(8):1462-9.
2010: A D Beggs; A R Latchford; H F A Vasen; G Moslein; A Alonso; S Aretz; L Bertario; I Blanco; S Bülow; J Burn; G Capella; C Colas; W Friedl; P Møller; F J Hes; H Järvinen; J-P Mecklin; F M Nagengast; Y Parc; R K S Phillips; W Hyer; M Ponz de Leon; L Renkonen-Sinisalo; J R Sampson; A Stormorken; S Tejpar; Huw J W Thomas; Juul Wijnen; Susan Clark; Shirley V Hodgson
Peutz-Jeghers syndrome: a systematic review and recommendations for management.
Gut 2010;59(7):975-86.
2010: Anneke Middeldorp; Shantie C Jagmohan-Changur; Heleen van der Klift; Marjo Van Puijenbroek; Jeanine J Houwing-Duistermaat; Emily Webb; Richard Houlston; Carli Tops; Hans F A Vasen; Peter Devilee; Hans Morreau; Tom van Wezel; Juul Wijnen
Comprehensive genetic analysis of seven large families with mismatch repair proficient colorectal cancer.
Genes, chromosomes & cancer 2010;49(6):539-48.
2010: H F A Vasen; G Möslein; A Alonso; S Aretz; I Bernstein; L Bertario; I Blanco; S Bulow; J Burn; G Capella; C Colas; C Engel; I Frayling; N Rahner; F J Hes; S Hodgson; J-P Mecklin; P Møller; T Myrhøj; F M Nagengast; Y Parc; M Ponz de Leon; L Renkonen-Sinisalo; J R Sampson; A Stormorken; S Tejpar; H J W Thomas; Juul Wijnen; J Lubinski; H Järvinen; E Claes; K Heinimann; J A Karagiannis; A Lindblom; I Dove-Edwin; H Müller
Recommendations to improve identification of hereditary and familial colorectal cancer in Europe.
Familial cancer 2010;9(2):109-15.
2010: Heleen van der Klift; Carli Tops; Elsa C Bik; Merel W Boogaard; Anne-Marijke Borgstein; Kerstin B M Hansson; Margreet G E M Ausems; Encarna Gomez Garcia; Andrew Green; Frederik J Hes; Louise Izatt; Liselotte P van Hest; Angel M Alonso; Annette H J T Vriends; Anja Wagner; Wendy A G van Zelst-Stams; Hans F A Vasen; Hans Morreau; Peter Devilee; Juul Wijnen
Quantification of sequence exchange events between PMS2 and PMS2CL provides a basis for improved mutation scanning of Lynch syndrome patients.
Human mutation 2010;31(5):578-87.
2010: Mark Drost; Jos e B M Zonneveld; Linda van Dijk; Hans Morreau; Carli Tops; Hans F A Vasen; Juul Wijnen; Niels De Wind
A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1.
Human mutation 2010;31(3):247-53.
2010: I P M Tomlinson; M Dunlop; H Campbell; B Zanke; S Gallinger; T Hudson; T Koessler; P D Pharoah; I Niittymäki; I Niittymäkix; S Tuupanen; S Tuupanenx; L A Aaltonen; K Hemminki; A Lindblom; A Försti; Oliver Sieber; L Lipton; Tom van Wezel; H Morreau; Juul Wijnen; P Devilee; K Matsuda; Y Nakamura; S Castellví-Bel; C Ruiz-Ponte; A Castells; A Carracedo; J W C Ho; P Sham; R M W Hofstra; P Vodicka; H Brenner; J Hampe; C Schafmayer; J Tepel; S Schreiber; H Völzke; M M Lerch; C A Schmidt; S Buch; V Moreno; C M Villanueva; P Peterlongo; P Radice; M M Echeverry; A Velez; Luis Carvajal Carmona; R Scott; S Penegar; P Broderick; A Tenesa; R S Houlston
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
British journal of cancer 2010;102(2):447-54.
2009: A Osorio; R L Milne; G Pita; P Peterlongo; T Heikkinen; J Simard; G Chenevix-Trench; A B Spurdle; J Beesley; X Chen; S Healey; S L Neuhausen; Y C Ding; F J Couch; X Wang; N Lindor; S Manoukian; M Barile; A Viel; L Tizzoni; C I Szabo; L Foretova; M Zikan; K Claes; M H Greene; P Mai; G Rennert; F Lejbkowicz; O Barnett-Griness; I L Andrulis; H Ozcelik; N Weerasooriya; A-M Gerdes; M Thomassen; D G Cruger; M A Caligo; Eitan Friedman; B Kaufman; Y Laitman; S Cohen; T Kontorovich; R Gershoni-Baruch; E Dagan; H Jernström; M S Askmalm; B Arver; B Malmer; S M Domchek; K L Nathanson; J Brunet; T Ramón Y Cajal; D Yannoukakos; U Hamann; F B L Hogervorst; S Verhoef; E B Gómez García; Juul Wijnen; A van den Ouweland; D F Easton; S Peock; M Cook; C T Oliver; D Frost; C Luccarini; D G Evans; Fiona Lalloo; R Eeles; G Pichert; J Cook; S Hodgson; P J Morrison; F Douglas; A K Godwin; O M Sinilnikova; L Barjhoux; D Stoppa-Lyonnet; V Moncoutier; S Giraud; C Cassini; L Olivier-Faivre; F Révillion; J-P Peyrat; D Muller; J-P Fricker; H T Lynch; E M John; S Buys; M Daly; J L Hopper; M B Terry; A Miron; Y Yassin; D Goldgar; C F Singer; D Gschwantler-Kaulich; G Pfeiler; A-C Spiess; Thomas V O Hansen; O T Johannsson; Tomas Kirchhoff; Kenneth Offit; K Kosarin; M Piedmonte; Gustavo Rodriguez; K Wakeley; J F Boggess; J Basil; P E Schwartz; S V Blank; A E Toland; M Montagna; C Casella; E N Imyanitov; A Allavena; R K Schmutzler; B Versmold; C Engel; A Meindl; N Ditsch; N Arnold; D Niederacher; H Deissler; B Fiebig; R Varon-Mateeva; D Schaefer; U G Froster; T Caldes; M de la Hoya; L McGuffog; A C Antoniou; H Nevanlinna; P Radice; J Benítez
Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).
British journal of cancer 2009;101(12):2048-54.
2009: Antonis C Antoniou; Olga M Sinilnikova; Lesley McGuffog; Sue Healey; Heli Nevanlinna; Tuomas Heikkinen; Jacques Simard; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Susan L Neuhausen; Yuan C Ding; Fergus J Couch; Xianshu Wang; Zachary Fredericksen; Paolo Peterlongo; Bernard Peissel; Bernardo Bonanni; Alessandra Viel; Loris Bernard; Paolo Radice; Csilla I Szabo; Lenka Foretova; Michal Zikan; Kathleen Claes; Mark H Greene; Phuong L Mai; Gad Rennert; Flavio Lejbkowicz; Irene L Andrulis; Hilmi Ozcelik; Gord Glendon; Anne-Marie Gerdes; Mads Thomassen; Lone Sunde; Maria A Caligo; Yael Laitman; Tair Kontorovich; Shimrit Cohen; Bella Kaufman; Efrat Dagan; Ruth Gershoni Baruch; Eitan Friedman; Katja Harbst; Gisela Barbany-Bustinza; Johanna Rantala; Hans Ehrencrona; Per Karlsson; Susan M Domchek; Katherine L Nathanson; Ana Osorio; Ignacio Blanco; Adriana Lasa; Javier Benítez; Ute Hamann; Frans B L Hogervorst; Matti A Rookus; J Margriet Collee; Peter Devilee; Marjolijn J Ligtenberg; Rob B van der Luijt; Cora M Aalfs; Quinten Waisfisz; Juul Wijnen; Cornelis E P van Roozendaal; Susan Peock; Margaret Cook; Debra Frost; Clare Oliver; Radka Platte; D Gareth Evans; Fiona Lalloo; Rosalind Eeles; Louise Izatt; Rosemarie Davidson; Carol Chu; Diana Eccles; Trevor Cole; Shirley Hodgson; Andrew K Godwin; Dominique Stoppa-Lyonnet; Bruno Buecher; Mélanie Léoné; Brigitte Bressac-de Paillerets; Audrey Remenieras; Olivier Caron; Gilbert M Lenoir; Nicolas Sevenet; Michel Longy; Sandra Fert Ferrer; Fabienne Prieur; David Goldgar; Alexander Miron; Esther M John; Saundra S Buys; Mary B Daly; John L Hopper; Mary Beth Terry; Yosuf Yassin; Christian Singer; Daphne Gschwantler-Kaulich; Christine Staudigl; Thomas v O Hansen; Rosa Bjork Barkardottir; Tomas Kirchhoff; Prodipto Pal; Kristi Kosarin; Kenneth Offit; Marion Piedmonte; Gustavo Rodriguez; Katie Wakeley; John F Boggess; Jack Basil; Peter E Schwartz; Stephanie V Blank; Amanda E Toland; Marco Montagna; Cinzia Casella; Evgeny N Imyanitov; Anna Allavena; Rita K Schmutzler; Beatrix Versmold; Christoph Engel; Alfons Meindl; Nina Ditsch; Norbert Arnold; Dieter Niederacher; Helmut Deissler; Britta Fiebig; Christian Suttner; Ines Schönbuchner; Dorothea Gadzicki; Trinidad Caldes; Miguel de la Hoya; Karen A Pooley; Douglas F Easton; Georgia Chenevix-Trench
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.
Human molecular genetics 2009;18(22):4442-56.
2009: Anneke Middeldorp; Shantie Jagmohan-Changur; Ronald van Eijk; Carli Tops; Peter Devilee; Hans F A Vasen; Frederik J Hes; Richard Houlston; Ian Tomlinson; Jeanine J Houwing-Duistermaat; Juul Wijnen; Hans Morreau; Tom van Wezel
Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):3062-7.
2009: Joel Vos; Christi J van Asperen; Juul Wijnen; Anne M Stiggelbout; Aad Tibben
Disentangling the Babylonian speech confusion in genetic counseling: an analysis of the reliability and validity of the nomenclature for BRCA1/2 DNA-test results other than pathogenic.
Genetics in medicine : official journal of the American College of Medical Genetics 2009;11(10):742-9.
2009: Sharon E Johnatty; Fergus J. Couch; Zachary Fredericksen; Robert Tarrell; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Daphne Gschwantler-Kaulich; Christian F Singer; Christine Fuerhauser; Anneliese Fink-Retter; Susan M Domchek; Katherine L Nathanson; Vernon S Pankratz; Noralane Lindor; Andrew K Godwin; Maria A Caligo; John Hopper; Melissa C Southey; Graham G Giles; Christina Justenhoven; Hiltrud Brauch; Ute Hamann; Yon-Dschun Ko; Tuomas Heikkinen; Kirsimari Aaltonen; Kristiina Aittomäki; Carl Blomqvist; Heli Nevanlinna; Per Hall; Kamila Czene; Jianjun Liu; Susan Peock; Margaret Cook; Radka Platte; D Gareth Evans; Fiona Lalloo; Rosalind Eeles; Gabriella Pichert; Diana Eccles; Rosemarie Davidson; Trevor Cole; Jackie Cook; Fiona Douglas; Carol Chu; Shirley Hodgson; Joan Paterson; Frans B L Hogervorst; Matti A Rookus; Caroline Seynaeve; Juul Wijnen; Maaike Vreeswijk; Marjolijn Ligtenberg; Rob B van der Luijt; Theo A M van Os; Hans J P Gille; Marinus J Blok; Claudine Issacs; Manjeet K Humphreys; Lesley McGuffog; Sue Healey; Olga Sinilnikova; Antonis C Antoniou; Douglas F Easton; Georgia Chenevix-Trench
No evidence that GATA3 rs570613 SNP modifies breast cancer risk.
Breast cancer research and treatment 2009;117(2):371-9.
2009: Leila Mohammadi; Maaike P Vreeswijk; Rogier Oldenburg; Ans van den Ouweland; Jan C Oosterwijk; Annemarie H Van Der Hout; Nicoline Hoogerbrugge; M J L Ligtenberg; Margreet G E M Ausems; Rob B van der Luijt; Charlotte J Dommering; Johan J Gille; Senno Verhoef; Frans B Hogervorst; Theo A M van Os; Encarna Gómez García; Marinus J Blok; Juul Wijnen; Quinta Helmer; Peter Devilee; Christi J van Asperen; Hans C van Houwelingen
A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example.
BMC cancer 2009;9():211.
2009: Carli M J Tops; Juul Wijnen; Frederik J Hes
Introduction to molecular and clinical genetics of colorectal cancer syndromes.
Best practice & research. Clinical gastroenterology 2009;23(2):127-46.
2009: Encarnación B Gómez García; Jan C Oosterwijk; Maarten Timmermans; Christi J van Asperen; Frans B L Hogervorst; Nicoline Hoogerbrugge; Rogier Oldenburg; Senno Verhoef; Charlotte J Dommering; Margreet G E M Ausems; Theo A M van Os; Annemarie H Van Der Hout; M J L Ligtenberg; Ans van den Ouweland; Rob B van der Luijt; Juul Wijnen; Jan J P Gille; Patrick J Lindsey; Peter Devilee; Marinus J Blok; Maaike P G Vreeswijk
A method to assess the clinical significance of unclassified variants in the BRCA1 and BRCA2 genes based on cancer family history.
Breast cancer research : BCR 2009;11(1):R8.
2009: Juul Wijnen; Richard M Brohet; Ronald van Eijk; Shantie Jagmohan-Changur; Anneke Middeldorp; Carli Tops; Mario van Puijenbroek; Margreet G E M Ausems; Encarna Gómez García; Frederik J Hes; Nicoline Hoogerbrugge; Fred H Menko; Theo A M van Os; Rolf Sijmons; Senno Verhoef; Anja Wagner; Fokko M Nagengast; Jan H Kleibeuker; Peter Devilee; Hans Morreau; David Goldgar; Ian P M Tomlinson; richard Houlston; Tom van Wezel; H F A Vasen
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.
Gastroenterology 2009;136(1):131-7.
2009: Maaike P G Vreeswijk; Jaennelle N Kraan; Heleen van der Klift; Geraldine R Vink; Cees J Cornelisse; Juul Wijnen; Egbert Bakker; Christi J van Asperen; Peter Devilee
Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice-site prediction programs.
Human mutation 2009;30(1):107-14.
2008: Alan Pittman; Emily Webb; Luis Carvajal Carmona; Kimberley Howarth; Maria Chiara Di Bernardo; Peter Broderick; Sarah Spain; Axel Walther; Amy Price; Kate Sullivan; Philip Twiss; Sarah Fielding; Andrew Rowan; Emma Jaeger; Jayaram Vijayakrishnan; Ian Chandler; Steven Penegar; Mobshra Qureshi; Steven Lubbe; Enric Domingo; Zoe Kemp; Ella Barclay; Wendy Wood; Lynn Martin; Maggie Gorman; Huw Thomas; Julian Peto; D Timothy Bishop; Richard Gray; Eamonn R Maher; Anneke Lucassen; David Kerr; Gareth R Evans; Tom van Wezel; Hans Morreau; Juul Wijnen; John L Hopper; Melissa C Southey; Graham G Giles; Gianluca Severi; Sergi Castellví-Bel; Clara Ruiz-Ponte; Angel Carracedo; Antoni Castells; Asta Försti; Kari Hemminki; Pavel Vodicka; Alessio Naccarati; Lara Lipton; Judy W C Ho; K K Cheng; Pak C Sham; J Luk; Jose A G Agúndez; Jose M Ladero; Miguel de la Hoya; Trinidad Caldés; Iina Niittymäki; Sari Tuupanen; Auli Karhu; Lauri A Aaltonen; Jean-Baptiste Cazier; axel walther; Richard S Houlston
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer.
Human molecular genetics 2008;17(23):3720-7.
2008: Eli Papaemmanuil; Luis Carvajal Carmona; Gabrielle S Sellick; Zoe Kemp; Emily Webb; Sarah Spain; Kate Sullivan; Ella Barclay; Steven Lubbe; Emma Jaeger; Jayaram Vijayakrishnan; Peter Broderick; Maggie Gorman; Lynn Martin; Anneke Lucassen; D Timothy Bishop; D Gareth Evans; Eamonn R Maher; Verena Steinke; Nils Rahner; Hans K Schackert; Timm O Goecke; Elke Holinski-Feder; Peter Propping; Tom van Wezel; Juul Wijnen; Jean-Baptiste Cazier; Huw Thomas; Richard S Houlston; Ian Tomlinson
Deciphering the genetics of hereditary non-syndromic colorectal cancer.
European journal of human genetics : EJHG 2008;16(12):1477-86.
2008: A Middeldorp; Marjo Van Puijenbroek; M Nielsen; W E Corver; Ekaterina S. Jordanova; Natalja T Ter Haar; C M J Tops; H F A Vasen; E H Lips; Ronald van Eijk; F J Hes; Jan Oosting; Juul Wijnen; Tom van Wezel; Hans Morreau
High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas.
The Journal of pathology 2008;216(1):25-31.
2008: Marijke Wasielewski; H F A Vasen; Juul Wijnen; Maartje Hooning; Dennis Dooijes; Carli Tops; Jan G M Klijn; Hanne Meijers-Heijboer; Mieke Schutte
CHEK2 1100delC is a susceptibility allele for HNPCC-related colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4989-94.
2008: Patrice Watson; H F A Vasen; Jukka-Pekka Mecklin; Inge Bernstein; Markku Aarnio; Heikki J Järvinen; Torben Myrhøj; Lone Sunde; Juul Wijnen; Henry T Lynch
The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome.
International journal of cancer. Journal international du cancer 2008;123(2):444-9.
2008: axel walther; Emily Webb; Luis Carvajal Carmona; Peter Broderick; Kimberley Howarth; Alan Pittman; Sarah Spain; Steven Lubbe; Axel Walther; Kate Sullivan; Emma Jaeger; Sarah Fielding; Andrew Rowan; Jayaram Vijayakrishnan; Enric Domingo; Ian Chandler; Zoe Kemp; Mobshra Qureshi; Susan M Farrington; Albert Tenesa; James G D Prendergast; Rebecca A Barnetson; Steven Penegar; Ella Barclay; Wendy Wood; Lynn Martin; Maggie Gorman; Huw Thomas; Julian Peto; Tim BISHOP; Richard Gray; Eamonn R Maher; Anneke Lucassen; David Kerr; D Gareth R Evans; Clemens Schafmayer; Stephan Buch; Henry Völzke; Jochen Hampe; Stefan Schreiber; Ulrich John; Thibaud Koessler; Paul Pharoah; Tom van Wezel; Hans Morreau; Juul Wijnen; John L Hopper; Melissa C Southey; Graham G Giles; Gianluca Severi; Sergi Castellví-Bel; Clara Ruiz-Ponte; Angel Carracedo; Antoni Castells; Asta Försti; Kari Hemminki; Pavel Vodicka; Alessio Naccarati; Lara Lipton; Judy W C Ho; K K Cheng; Pak C Sham; J Luk; Jose A G Agúndez; Jose M Ladero; Miguel de la Hoya; Trinidad Caldés; Iina Niittymäki; Sari Tuupanen; Auli Karhu; Lauri Aaltonen; Jean-Baptiste Cazier; Harry Campbell; Malcolm G Dunlop; Richard S Houlston
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.
Nature genetics 2008;40(5):623-30.
2008: Hans Vasen; G Möslein; A Alonso; S Aretz; I Bernstein; L Bertario; I Blanco; S Bülow; J Burn; G Capella; C Colas; Christoph Engel; I Frayling; W Friedl; F J Hes; S Hodgson; H Järvinen; J-P Mecklin; P Møller; T Myrhøi; F M Nagengast; Y Parc; R Phillips; Susan Clark; M Ponz de Leon; L Renkonen-Sinisalo; J R Sampson; A Stormorken; S Tejpar; H J W Thomas; Juul Wijnen
Guidelines for the clinical management of familial adenomatous polyposis (FAP).
Gut 2008;57(5):704-13.
2008: Marry H Nieuwenhuis; Wouter De Vos Tot Nederveen Cappel; Akke Botma; Fokko M Nagengast; Jan H Kleibeuker; E M H Mathus-Vliegen; Evelien Dekker; Jan Dees; Juul Wijnen; H F A Vasen
Desmoid tumors in a dutch cohort of patients with familial adenomatous polyposis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(2):215-9.
2008: Marjo Van Puijenbroek; Anneke Middeldorp; Carli Tops; Ronald van Eijk; Heleen van der Klift; H F A Vasen; Juul Wijnen; Frederik J Hes; Jan Oosting; Tom van Wezel; Hans Morreau
Genome-wide copy neutral LOH is infrequent in familial and sporadic microsatellite unstable carcinomas.
Familial cancer 2008;7(4):319-30.
2008: Frederik J Hes; Maartje Nielsen; Elsa Bik; D Konvalinka; Juul Wijnen; Egbert Bakker; H F A Vasen; Martijn H Breuning; Carli Tops
Somatic APC mosaicism: an underestimated cause of polyposis coli.
Gut 2008;57(1):71-6.
2007: H F A Vasen; Gabriela Möslein; A Alonso; I Bernstein; L Bertario; I Blanco; John Burn; G Capella; Christoph Engel; Ian M Frayling; Waltraut Friedl; Frederik J Hes; Shirley Hodgson; Jukka-Pekka Mecklin; Pål Møller; Fokko M Nagengast; Y Parc; Laura Renkonen-Sinisalo; Julian R Sampson; Astrid T Stormorken; Juul Wijnen
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).
Journal of medical genetics 2007;44(6):353-62.
2007: Maartje Nielsen; Frederik J Hes; Fokko M Nagengast; Janneke Weiss; E M H Mathus-Vliegen; Hans Morreau; Martijn H Breuning; Juul Wijnen; Carli Tops; H F A Vasen
Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
Clinical genetics 2007;71(5):427-33.
2007: Anneke Middeldorp; Shantie Jagmohan-Changur; Quinta Helmer; Heleen van der Klift; Carli Tops; H F A Vasen; Peter Devilee; Hans Morreau; Jeanine J Houwing-Duistermaat; Juul Wijnen; Tom van Wezel
A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer.
BMC cancer 2007;7():6.
2007: Marjo Van Puijenbroek; Maartje Nielsen; Tjitske H C M Reinards; Janneke Weiss; Anja Wagner; Yvonne M C Hendriks; H F A Vasen; Carli Tops; Juul Wijnen; Tom van Wezel; Frederik J Hes; Hans Morreau
The natural history of a combined defect in MSH6 and MUTYH in a HNPCC family.
Familial cancer 2007;6(1):43-51.
2006: Yvonne M C Hendriks; Andrea E De Jong; Hans Morreau; Carli Tops; H F A Vasen; Juul Wijnen; Martijn H Breuning; Annette H J T Bröcker-Vriends
Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians.
CA: a cancer journal for clinicians 2006;56(4):213-25.
2006: Jae-Gahb Park; Duck-Woo Kim; Chang Won Hong; Byung-Ho Nam; Young-Kyoung Shin; Sung-Hye Hong; Il-Jin Kim; Seok-Byung Lim; Melyssa Aronson; Marie Luise Bisgaard; Gregor J Brown; John Burn; Elizabeth Chow; Peggy Conrad; Fiona Douglas; Malcolm Dunlop; James Ford; Marc S Greenblatt; Jarvinen Heikki; Karl Heinimann; Elly L Lynch; Finlay Macrae; Wendy C McKinnon; Gabriela Möeslein; Benedito Mauro Rossi; Paul Rozen; Lyn Schofield; Carlos Vaccaro; Hans Vasen; Mary Velthuizen; Alessandra Viel; Juul Wijnen
Germ line mutations of mismatch repair genes in hereditary nonpolyposis colorectal cancer patients with small bowel cancer: International Society for Gastrointestinal Hereditary Tumours Collaborative Study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3389-93.
2006: Yvonne M C Hendriks; Shantie Jagmohan-Changur; Heleen van der Klift; Hans Morreau; Marjo Van Puijenbroek; Carli Tops; Theo A M van Os; Anja Wagner; Margreet G E M Ausems; Encarna Gomez; Martijn H Breuning; Annette H J T Bröcker-Vriends; H F A Vasen; Juul Wijnen
Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome).
Gastroenterology 2006;130(2):312-22.
2005: Heleen van der Klift; Juul Wijnen; Anja Wagner; Paul Verkuilen; Carli Tops; Robyn Otway; M R J Kohonen-Corish; H F A Vasen; Cristina Oliani; Daniela Barana; Pal Moller; Celia Delozier-Blanchet; Pierre Hutter; William D Foulkes; Henry T Lynch; John Burn; Gabriela Möslein; Riccardo Fodde
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
Genes, chromosomes & cancer 2005;44(2):123-38.
2005: Maartje Nielsen; Patrick F Franken; T H C M Reinards; Janneke Weiss; Anja Wagner; Heleen van der Klift; S Kloosterman; J J Houwing-Duistermaat; Cora M Aalfs; Margreet G E M Ausems; Annette H J T Bröcker-Vriends; E B Gomez Garcia; Nicoline Hoogerbrugge; Fred H Menko; Rolf Sijmons; Senno Verhoef; Ernst J Kuipers; Hans Morreau; Martijn H Breuning; Carli Tops; Juul Wijnen; H F A Vasen; Riccardo Fodde; Frederik J Hes
Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP).
Journal of medical genetics 2005;42(9):e54.
2005: Astrid T Stormorken; Inger Marie Bowitz Lothe; Tove Norèn; Elin H Kure; Steinar Aase; Juul Wijnen; Jaran Apold; Ketil Heimdal; Pål Møller
Immunohistochemistry identifies carriers of mismatch repair gene defects causing hereditary nonpolyposis colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(21):4705-12.
2005: Yansong Bian; Trinidad Caldes; Juul Wijnen; Patrick Franken; H F A Vasen; Virginia G Kaklamani; Khedoudja Nafa; Paolo Peterlongo; Nathan Ellis; John A Baron; John Burn; Gabriela Moeslein; Patrick J Morrison; Yu Chen; Habibul Ahsan; Patrice Watson; Henry T Lynch; Albert de La Chapelle; Riccardo Fodde; Boris Pasche
TGFBR1*6A may contribute to hereditary colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(13):3074-8.
2005: Anja Wagner; Ingrid van Kessel; Mieke Kriege; Carli Tops; Juul Wijnen; H F A Vasen; Conny A van der Meer; Iris van Oostrom; Hanne Meijers-Heijboer
Long term follow-up of HNPCC gene mutation carriers: compliance with screening and satisfaction with counseling and screening procedures.
Familial cancer 2005;4(4):295-300.
2004: Yvonne M C Hendriks; Anja Wagner; Hans Morreau; Fred H Menko; Astrid T Stormorken; Franz Quehenberger; Lodewijk A Sandkuijl; Pål Møller; Maurizio Genuardi; Hans C van Houwelingen; Carli Tops; Marjo Van Puijenbroek; Paul Verkuijlen; Gemma G Kenter; Anneke Van Mil; Hanne Meijers-Heijboer; Gita B Tan; Martijn H Breuning; Riccardo Fodde; Juul Wijnen; Annette H J T Bröcker-Vriends; H F A Vasen
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
Gastroenterology 2004;127(1):17-25.
2004: Daniela Barana; Heleen van der Klift; Juul Wijnen; Elena Dalla Longa; Paolo Radice; Gian Luigi Cetto; Riccardo Fodde; Cristina Oliani
Spectrum of genetic alterations in Muir-Torre syndrome is the same as in HNPCC.
American journal of medical genetics. Part A 2004;125A(3):318-9.
2004: Henry T Lynch; Stephanie M Coronel; Ross Okimoto; Heather Hampel; Kevin Sweet; Jane F Lynch; Alicia Barrows; Juul Wijnen; Heleen van der Klift; Patrick Franken; Anja Wagner; Riccardo Fodde; Albert de La Chapelle
A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the United States.
JAMA : the journal of the American Medical Association 2004;291(6):718-24.
2004: Andrea E De Jong; Marjo Van Puijenbroek; Yvonne M C Hendriks; Carli Tops; Juul Wijnen; Margreet G E M Ausems; Hanne Meijers-Heijboer; Anja Wagner; Theo A M van Os; Annette H J T Bröcker-Vriends; H F A Vasen; Hans Morreau
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(3):972-80.
2004: H F A Vasen; Yvonne M C Hendriks; Andrea E De Jong; Marjo Van Puijenbroek; Carli Tops; Annette H J T Bröcker-Vriends; Juul Wijnen; Hans Morreau
Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.
Disease markers 2004;20(4-5):207-13.
2004: Andrea E De Jong; Hans Morreau; Marjo Van Puijenbroek; Paul H C Eilers; Juul Wijnen; Fokko M Nagengast; Gerrit Griffioen; Annemieke Cats; Fred H Menko; Jan H Kleibeuker; H F A Vasen
The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC.
Gastroenterology 2004;126(1):42-8.
2003: claudio soravia; Heleen van der Klift; Marie-Anne Bründler; Jean-Louis Blouin; Juul Wijnen; Pierre Hutter; Riccardo Fodde; Celia Delozier-Blanchet
Prostate cancer is part of the hereditary non-polyposis colorectal cancer (HNPCC) tumor spectrum.
American journal of medical genetics. Part A 2003;121A(2):159-62.
2003: Hanne Meijers-Heijboer; Juul Wijnen; H F A Vasen; Marijke Wasielewski; Anja Wagner; Antoinette Hollestelle; Fons Elstrodt; Renate van den Bos; Anja de Snoo; Grace Tjon A Fat; Cecile T M Brekelmans; Shantie Jagmohan; Patrick Franken; Paul Verkuijlen; Ans M W van den Ouweland; Pamela Chapman; Carli Tops; Gabriela Möslein; John Burn; Henry T Lynch; Jan G M Klijn; Riccardo Fodde; Mieke Schutte
The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.
American journal of human genetics 2003;72(5):1308-14.
2003: Anja Wagner; Alicia Barrows; Juul Wijnen; Heleen van der Klift; Patrick F Franken; Paul Verkuijlen; Hidewaki Nakagawa; Marjan Geugien; Shantie Jaghmohan-Changur; Cor Breukel; Hanne Meijers-Heijboer; Hans Morreau; Marjo Van Puijenbroek; John Burn; Stephanie M Coronel; Yulia Kinarski; Ross Okimoto; Patrice Watson; Jane F Lynch; Albert de La Chapelle; Henry T Lynch; Riccardo Fodde
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
American journal of human genetics 2003;72(5):1088-100.
2003: Henry T Lynch; Rodney J Taylor; Jane F Lynch; Joseph A Knezetic; Alicia Barrows; Riccardo Fodde; Juul Wijnen; Anja Wagner
Multiple primary cancer, including transitional cell carcinoma of the upper uroepithelial tract in a multigeneration HNPCC family: molecular genetic, diagnostic, and management implications.
The American journal of gastroenterology 2003;98(3):664-70.
2003: Yvonne M C Hendriks; Patrick Franken; Jan Willem F Dierssen; Wiljo J F De Leeuw; Juul Wijnen; Enno J Dreef; Carli Tops; Martijn H Breuning; Annette H J T Bröcker-Vriends; H F A Vasen; Riccardo Fodde; Hans Morreau
Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.
The American journal of pathology 2003;162(2):469-77.
2003: Astrid T Stormorken; Wolfram Müller; Annika Lindblom; Ketil Heimdal; Steinar Aase; Inger Marie Bowitz Lothe; Tove Norèn; Juul Wijnen; Gabriela Möslein; Pål Møller
The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours.
Familial cancer 2003;2(1):9-13.
2003: Shantie Jagmohan-Changur; Taija Poikonen; Susa Vilkki; Virpi Launonen; Friedrik P Wikman; Torben F Orntoft; Pål Møller; H F A Vasen; Carli Tops; Richard D Kolodner; Jukka-Pekka Mecklin; Heikki Järvinen; Stephen Bevan; richard Houlston; Lauri A Aaltonen; Riccardo Fodde; Juul Wijnen; Auli Karhu
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer.
Cancer research 2003;63(1):154-8.
2002: Anja Wagner; Carli Tops; Juul Wijnen; K Zwinderman; Conny A van der Meer; M Kets; Martinus F Niermeijer; Jan G M Klijn; Aad Tibben; H F A Vasen; Hanne Meijers-Heijboer
Genetic testing in hereditary non-polyposis colorectal cancer families with a MSH2, MLH1, or MSH6 mutation.
Journal of medical genetics 2002;39(11):833-7.
2002: Johan J P Gille; Frans B L Hogervorst; Gerard Pals; Juul Wijnen; R J van Schooten; Charlotte Dommering; Gerrit A Meijer; Mikael E Craanen; petra nederlof; Daphne de Jong; Cathal J McElgunn; Jan P Schouten; Fred H Menko
Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach.
British journal of cancer 2002;87(8):892-7.
2002: Anja Wagner; Heleen van der Klift; Patrick Franken; Juul Wijnen; Cor Breukel; Vladimir Bezrookove; Ron Smits; Yulia Kinarsky; Alicia Barrows; Barbara Franklin; Jane Lynch; Henry T Lynch; Riccardo Fodde
A 10-Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred.
Genes, chromosomes & cancer 2002;35(1):49-57.
2002: Pierre Hutter; Juul Wijnen; Claudine Rey-Berthod; Isabelle Thiffault; Paul Verkuijlen; David Farber; Nancy Hamel; B Bapat; S N Thibodeau; John Burn; J Wu; Elizabeth MacNamara; Karl Heinimann; George Chong; William D Foulkes
An MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1.
Journal of medical genetics 2002;39(5):323-7.
2002: Jae-Gahb Park; H F A Vasen; Young Jin Park; Kyu Joo Park; Paivi Peltomaki; Maurizio Ponzo de Leon; Miguel A Rodriguez-Bigas; Jan Lubinski; Nicholas E Beck; Marie-Luise Bisgaard; Michiko Miyaki; Juul Wijnen; Shozo Baba; Annika Lindblom; Lisa Madlensky; Henry T Lynch
Suspected HNPCC and Amsterdam criteria II: evaluation of mutation detection rate, an international collaborative study.
International journal of colorectal disease 2002;17(2):109-14.
2002: Elmar S D de Pauw; Sigrid A Otto; Juul Wijnen; Jaak M Vossen; Margreet H van Weel; Hans J Tanke; Frank Miedema; Rein Willemze; Helene Roelofs; Willem E Fibbe
Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion.
British journal of haematology 2002;116(2):491-6.
2001: H F A Vasen; Astrid T Stormorken; Fred H Menko; Fokko M Nagengast; Jan H Kleibeuker; Gerrit Griffioen; Babs G Taal; Pal Moller; Juul Wijnen
MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(20):4074-80.
2001: Wiljo J F De Leeuw; Marjo Van Puijenbroek; R Merx; Juul Wijnen; Annette H J T Bröcker-Vriends; Carli Tops; H F A Vasen; Cees J Cornelisse; Hans Morreau
Bias in detection of instability of the (C)8 mononucleotide repeat of MSH6 in tumours from HNPCC patients.
Oncogene 2001;20(43):6241-4.
2001: Anja Wagner; Yvonne M C Hendriks; E Johanna Meijers-Heijboer; Wiljo J F De Leeuw; Hans Morreau; Robert M W Hofstra; Carli Tops; E Bik; Annette H J T Bröcker-Vriends; Conny A van der Meer; Dick Lindhout; H F A Vasen; Martijn H Breuning; Cees J Cornelisse; C van Krimpen; Martinus F Niermeijer; A H Zwinderman; Juul Wijnen; Riccardo Fodde
Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree.
Journal of medical genetics 2001;38(5):318-22.
2001: Juul Wijnen; H Morreau; H F A Vasen
[From gene to disease; from DNA 'mismatch' repair genes to hereditary non-polyposis colorectal carcinoma].
Nederlands tijdschrift voor geneeskunde 2001;145(16):780-2.
2001: Astrid T Stormorken; W Müller; B Lemkemeyer; Jaran Apold; Juul Wijnen; Riccardo Fodde; Gabriela Möslein; Pål Møller
Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry.
Familial cancer 2001;1(3-4):169-73.
2000: T Peelen; Wiljo J F De Leeuw; K van Lent; Hans Morreau; Ronald van Eijk; Marcel van Vliet; Juul Wijnen; M J L Ligtenberg; HB Ginjaar; R Zweemer; Fred H Menko; Riccardo Fodde; Gert-Jan B van Ommen; H F A Vasen; Cees J Cornelisse; Peter Devilee
Genetic analysis of a breast-ovarian cancer family, with 7 cases of colorectal cancer linked to BRCA1, fails to support a role for BRCA1 in colorectal tumorigenesis.
International journal of cancer. Journal international du cancer 2000;88(5):778-82.
2000: Rolf Sijmons; Robert M W Hofstra; Harry Hollema; Rob G J Mensink; Annemarie H Van Der Hout; H Hoekstra; Jan H Kleibeuker; Willemina M Molenaar; Juul Wijnen; R Fodde; H F A Vasen; Charles H C M Buys
Inclusion of malignant fibrous histiocytoma in the tumour spectrum associated with hereditary non-polyposis colorectal cancer.
Genes, chromosomes & cancer 2000;29(4):353-5.
2000: Wiljo J F De Leeuw; Jan Willem F Dierssen; H F A Vasen; Juul Wijnen; Gemma G Kenter; Hanne Meijers-Heijboer; A Brocker-Vriends; Astrid T Stormorken; Pal Moller; Fred H Menko; Cees J Cornelisse; Hans Morreau
Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients.
The Journal of pathology 2000;192(3):328-35.
2000: Paulo Fidalgo; M R Almeida; S West; C Gaspar; Lara Maia; Juul Wijnen; Cristina Albuquerque; A Curtis; Marília Cravo; Riccardo Fodde; C N Leitao; J Burn
Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach.
European journal of human genetics : EJHG 2000;8(1):49-53.
1999: Mustafa Yavuz Köker; Rob van Zwieten; Juul Wijnen; Félix Gómez-Gallego; Martin de Boer; D Stevens; C J Pronk-Admiraal; T de Rijk; C J van Noorden; Ron S Weening; Tom Vulliamy; J E Ploem; Philip J Mason; José M Bautista; PM Khan; E Beutler
Molecular basis and enzymatic properties of glucose 6-phosphate dehydrogenase volendam, leading to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections.
Blood 1999;94(9):2955-62.
1999: Juul Wijnen; Wiljo J F De Leeuw; H F A Vasen; Heleen van der Klift; Pål Møller; Astrid T Stormorken; Hanne Meijers-Heijboer; Dick Lindhout; Fred H Menko; Sandra Vossen; Gabriela Möslein; Carli Tops; Annette H J T Bröcker-Vriends; Y Wu; Robert M W Hofstra; Rolf Sijmons; Cees J Cornelisse; Hans Morreau; Riccardo Fodde
Familial endometrial cancer in female carriers of MSH6 germline mutations.
Nature genetics 1999;23(2):142-4.
1999: Jae-Gahb Park; Y J Park; Juul Wijnen; H F A Vasen
Gene-environment interaction in hereditary nonpolyposis colorectal cancer with implications for diagnosis and genetic testing.
International journal of cancer. Journal international du cancer 1999;82(4):516-9.
1999: George A Calin; Juul Wijnen; Heleen van der Klift; A Ionita; A Mulder; Cor Breukel; Ron Smits; H Dauwerse; K Hansson; S Calin; D Stefanescu; Alexandru Oproiu; Riccardo Fodde
Marfan-like habitus and familial adenomatous polyposis in two unrelated males: a significant association?
European journal of human genetics : EJHG 1999;7(5):609-14.
1999: Fred H Menko; Gerrit Griffioen; Juul Wijnen; Carli Tops; Riccardo Fodde; Hans Vasen
[Genetics of colorectal cancer. II. Hereditary background of sporadic and familial colorectal cancer].
Nederlands tijdschrift voor geneeskunde 1999;143(23):1207-11.
1999: Fred H Menko; Gerrit Griffioen; Juul Wijnen; Carli Tops; Riccardo Fodde; Hans Vasen
[Genetics of colorectal cancer. I. Non-polyposis and polyposis forms of hereditary colorectal cancer].
Nederlands tijdschrift voor geneeskunde 1999;143(23):1201-6.
1999: Jae-Gahb Park; H F A Vasen; Kyu Joo Park; Paivi Peltomaki; Maurizio Ponz de Leon; Miguel A Rodriguez-Bigas; J Lubinski; N E Beck; Marie-Luise Bisgaard; M Miyaki; Juul Wijnen; S Baba; Henry T Lynch
Suspected hereditary nonpolyposis colorectal cancer: International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) criteria and results of genetic diagnosis.
Diseases of the colon and rectum 1999;42(6):710-5; discussion 715-6.
1999: H F A Vasen; Juul Wijnen
Clinical implications of genetic testing of hereditary nonpolyposis colorectal cancer.
Cytogenetics and cell genetics 1999;86(2):136-9.
1998: Juul Wijnen; Heleen van der Klift; H F A Vasen; PM Khan; Fred H Menko; Carli Tops; Hanne Meijers-Heijboer; Dick Lindhout; Pål Møller; Riccardo Fodde
MSH2 genomic deletions are a frequent cause of HNPCC.
Nature genetics 1998;20(4):326-8.
1998: Juul Wijnen; H F A Vasen; PM Khan; Aeilko H Zwinderman; Heleen van der Klift; A Mulder; Carli Tops; Pål Møller; Riccardo Fodde
Clinical findings with implications for genetic testing in families with clustering of colorectal cancer.
The New England journal of medicine 1998;339(8):511-8.
1998: Fred H Menko; Juul Wijnen; H F A Vasen; Rolf Sijmons; PM Khan
Familial and hereditary non-polyposis colorectal cancer: issues relevant for surgical practice.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;146():20-31.
1997: D van Zoeren-Grobben; Jan H N Lindeman; E Houdkamp; Ralf M W Moison; Juul Wijnen; Howard M Berger
Markers of oxidative stress and antioxidant activity in plasma and erythrocytes in neonatal respiratory distress syndrome.
Acta paediatrica (Oslo, Norway : 1992) 1997;86(12):1356-62.
1997: Juul Wijnen; PM Khan; H F A Vasen; Heleen van der Klift; A Mulder; I van Leeuwen-Cornelisse; Bert Bakker; Monique Losekoot; Pål Møller; Riccardo Fodde
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
American journal of human genetics 1997;61(2):329-35.
1997: Rob B van der Luijt; PM Khan; H F A Vasen; Carli Tops; I S van Leeuwen-Cornelisse; Juul Wijnen; Heleen van der Klift; Rob Plug; Gerrit Griffioen; Riccardo Fodde
Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germline mutations identified by DGGE, PTT, and southern analysis.
Human mutation 1997;9(1):7-16.
1996: S Bala; Cornelia Kraus; Juul Wijnen; P Meera Khan; Wolfgang G Ballhausen
Multiple products in the protein truncation test due to alternative splicing in the adenomatous polyposis coli (APC) gene.
Human genetics 1996;98(5):528-33.
1996: M R J Kohonen-Corish; V L Ross; WF Doe; D A Kool; E Edkins; I Faragher; Juul Wijnen; PM Khan; F Macrae; D James B St John
RNA-based mutation screening in hereditary nonpolyposis colorectal cancer.
American journal of human genetics 1996;59(4):818-24.
1996: H F A Vasen; Juul Wijnen; Fred H Menko; J H Kleibeuker; Babs G Taal; Gerrit Griffioen; F M Nagengast; E H Meijers-Heijboer; Lucio Bertario; Liliana Varesco; M L Bisgaard; J Mohr; Riccardo Fodde; PM Khan
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.
Gastroenterology 1996;110(4):1020-7.
1996: Juul Wijnen; PM Khan; H F A Vasen; Fred H Menko; Heleen van der Klift; M van den Broek; I van Leeuwen-Cornelisse; F Nagengast; E J Meijers-Heijboer; Dick Lindhout; Gerrit Griffioen; A Cats; J Kleibeuker; Liliana Varesco; Lucio Bertario; M L Bisgaard; J Mohr; R Kolodner; Riccardo Fodde
Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16.
American journal of human genetics 1996;58(2):300-7.
1996: Fred H Menko; Juul Wijnen; PM Khan; Hans Vasen; M H Oosterwijk
Genetic counseling in hereditary nonpolyposis colorectal cancer.
Oncology (Williston Park, N.Y.) 1996;10(1):71-6; discussion 81-2.
1995: Juul Wijnen; H F A Vasen; PM Khan; Fred H Menko; Heleen van der Klift; C van Leeuwen; M van den Broek; I van Leeuwen-Cornelisse; F Nagengast; A Meijers-Heijboer
Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis.
American journal of human genetics 1995;56(5):1060-6.
1994: Juul Wijnen; Riccardo Fodde; PM Khan
DGGE polymorphism in intron 10 of MSH2, the HNPCC gene.
Human molecular genetics 1994;3(12):2268.
1994: Fred H Menko; R H Verheijen; E Everhardt; L A Louwé; Juul Wijnen; S C Band; R J Felt-Bersma; Hans Vasen; PM Khan
Endometrial cancer in four sisters: report of a kindred with presumed cancer family syndrome.
Gynecologic oncology 1994;54(2):171-4.
1994: R F Schapers; R P Pauwels; Juul Wijnen; J W Arends; F B Thunnissen; J W Coebergh; A W Smeets; F T Bosman
A simplified grading method of transitional cell carcinoma of the urinary bladder: reproducibility, clinical significance and comparison with other prognostic parameters.
British journal of urology 1994;73(6):625-31.
1994: J E van Leeuwen; Maarten J D van Tol; A M Joosten; Juul Wijnen; P J Verweij; PM Khan; Jaak M Vossen
Persistence of host-type hematopoiesis after allogeneic bone marrow transplantation for leukemia is significantly related to the recipient's age and/or the conditioning regimen, but it is not associated with an increased risk of relapse.
Blood 1994;83(10):3059-67.
1993: E J Breslau-Siderius; Juul Wijnen; J G Dauwerse; Joke de Pater; F A Beemer; PM Khan
Paternal duplication of chromosome 5q11.2-5q14 in a male born with craniostenosis, ear tags, kidney dysplasia and several other anomalies.
Human genetics 1993;92(5):481-5.
1993: J E van Leeuwen; Maarten J D van Tol; A M Joosten; Juul Wijnen; PM Khan; Jaak M Vossen
Mixed T-lymphoid chimerism after allogeneic bone marrow transplantation for hematologic malignancies of children is not correlated with relapse.
Blood 1993;82(6):1921-8.
1993: B Renault; M van den Broek; Riccardo Fodde; Juul Wijnen; N S Pellegata; Dino Amadori; PM Khan; Guglielmina Nadia Ranzani
Base transitions are the most frequent genetic changes at P53 in gastric cancer.
Cancer research 1993;53(11):2614-7.
1992: Riccardo Fodde; R van der Luijt; Juul Wijnen; Carli Tops; Heleen van der Klift; I van Leeuwen-Cornelisse; Gerrit Griffioen; H F A Vasen; PM Khan
Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis.
Genomics 1992;13(4):1162-8.
1991: Juul Wijnen; Carli Tops; Cor Breukel; C van Leeuwen; A Goverde; Heleen van der Klift; Riccardo Fodde; PM Khan
CA repeat polymorphism from YAC JW25 at the D5S318 locus, distal to adenomatous polyposis coli (APC).
Nucleic acids research 1991;19(24):6965.
1991: J E van Leeuwen; Maarten J D van Tol; B G Bodzinga; Juul Wijnen; M van der Keur; A M Joosten; Hans J Tanke; Jaak M Vossen; PM Khan
Detection of mixed chimaerism in flow-sorted cell subpopulations by PCR-amplified VNTR markers after allogeneic bone marrow transplantation.
British journal of haematology 1991;79(2):218-25.
1991: Carli Tops; Cor Breukel; Heleen van der Klift; I S von Leeuwen; Juul Wijnen; Gerrit Griffioen; H F A Vasen; F C den Hartog Jager; F M Nagengast; Cornelis B H W Lamers
A new deletion polymorphism at D5S71 raises the linkage information on adenomatous polyposis coli: implications for presymptomatic diagnosis.
Human genetics 1991;86(4):365-8.
1990: R H Brakenhoff; A H Guerts van Kessel; M Oldenburg; Juul Wijnen; Hans Bloemendal; P Meera Khan; J G Schoenmakers
Human alpha B-crystallin (CRYA2) gene mapped to chromosome 11q12-q23.
Human genetics 1990;85(2):237-40.
1990: E A van den Berg; E le Clercq; Cornelis Kluft; T Koide; A van der Zee; M Oldenburg; Juul Wijnen; P Meera Khan
Assignment of the human gene for histidine-rich glycoprotein to chromosome 3.
Genomics 1990;7(2):276-9.
1990: Cor Breukel; Juul Wijnen; Carli Tops; H vd Klift; Hans Dauwerse; PM Khan
Vector-Alu PCR: a rapid step in mapping cosmids and YACs.
Nucleic acids research 1990;18(10):3097.
1990: Winand N M Dinjens; Edith Van Der Linden; C M Signet; Juul Wijnen; P Meera Khan; J Ten Kate; Fred T Bosman
Solid-phase adsorption of antigens for efficient production of antibodies reactive with native and fixed tissue antigens.
Journal of immunological methods 1990;126(2):175-82.
1989: Carli Tops; Juul Wijnen; Gerrit Griffioen; I S von Leeuwen; H F A Vasen; F C den Hartog Jager; Cor Breukel; F M Nagengast; Heleen van der Klift; Cornelis B H W Lamers
Presymptomatic diagnosis of familial adenomatous polyposis by bridging DNA markers.
Lancet 1989;2(8676):1361-3.
1989: Winand N M Dinjens; J ten Kate; Edith Van Der Linden; Juul Wijnen; PM Khan; Fred T Bosman
Distribution of adenosine deaminase complexing protein (ADCP) in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(12):1869-75.
1989: Winand N M Dinjens; J ten Kate; Juul Wijnen; Edith Van Der Linden; C J Beek; Marie-Hélène Lenders; PM Khan; Fred T Bosman
Distribution of adenosine deaminase-complexing protein in murine tissues.
The Journal of biological chemistry 1989;264(32):19215-20.
1989: Arie van Haeringen; Wilma Bergman; M R Nelen; E van der Kooij-Meijs; I Hendrikse; Juul Wijnen; PM Khan; E C Klasen; Rune R Frants
Exclusion of the dysplastic nevus syndrome (DNS) locus from the short arm of chromosome 1 by linkage studies in Dutch families.
Genomics 1989;5(1):61-4.
1989: G L van Rens; Jos M H Raats; H P Driessen; M Oldenburg; Juul Wijnen; PM Khan; Wilfried W de Jong; Hans Bloemendal
Structure of the bovine eye lens gamma s-crystallin gene (formerly beta s).
Gene 1989;78(2):225-33.
1988: Riccardo Fodde; Monique Losekoot; M H van den Broek; M Oldenburg; N Rashida; A Schreuder; Juul Wijnen; Piero C Giordano; N V Nayudu; PM Khan
Prevalence and molecular heterogeneity of alfa+ thalassemia in two tribal populations from Andhra Pradesh, India.
Human genetics 1988;80(2):157-60.
1988: P Meera Khan; Carli Tops; M vd Broek; Cor Breukel; Juul Wijnen; M Oldenburg; J vd Bos; I S van Leeuwen-Cornelisse; H F A Vasen; Gerrit Griffioen
Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22.
Human genetics 1988;79(2):183-5.
1987: T M Berkvens; E J Gerritsen; M Oldenburg; Cor Breukel; Juul Wijnen; Hans van Ormondt; Jaak M Vossen; Alex J van der Eb; P Meera Khan
Severe combined immune deficiency due to a homozygous 3.2-kb deletion spanning the promoter and first exon of the adenosine deaminase gene.
Nucleic acids research 1987;15(22):9365-78.
1987: M H Breuning; K Madan; M Verjaal; Juul Wijnen; P Meera Khan; P L Pearson
Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP.
Human genetics 1987;76(3):287-9.
1987: P Meera Khan; Juul Wijnen; A Hagenbeek; J M Vossen
Isozymes as host-donor blood cell "tracers" in bone marrow transplantation.
Isozymes 1987;16():125-44.
1986: P Meera Khan; C Verma; L M Wijnen; Juul Wijnen; H K Prins; L E Nijenhuis
Electrotypes and formal genetics of red cell glutathione peroxidase (GPX1) in the Djuka of Surinam.
American journal of human genetics 1986;38(5):712-23.
1986: J H Verheijen; R Visse; Juul Wijnen; G T Chang; C Kluft; P Meera Khan
Assignment of the human tissue-type plasminogen activator gene (PLAT) to chromosome 8.
Human genetics 1986;72(2):153-6.
1985: J Ten Kate; Juul Wijnen; J Boldewijn; PM Khan; F T Bosman
Immunohistochemical localization of adenosine deaminase complexing protein in intestinal mucosa and in colorectal adenocarcinoma as a marker for tumour cell heterogeneity.
The Histochemical journal 1985;17(1):23-31.
1984: J ten Kate; Juul Wijnen; R G van der Goes; R Quadt; G Griffioen; F T Bosman; PM Khan
Quantitative changes in adenosine deaminase isoenzymes in human colorectal adenocarcinomas.
Cancer research 1984;44(10):4688-92.
1984: J ten Kate; Juul Wijnen; E Herbschleb-Voogt; G Griffioen; F T Bosman; PM Khan
Adenosine deaminase (ADA; E.C. no. 3.5.4.4.) in colorectal adenocarcinoma in man.
Advances in experimental medicine and biology 1984;165 Pt B():299-303.
1983: P Meera Khan; L M Wijnen; Juul Wijnen; K H Grzeschik
Electrophoretic characterization and genetics of human biliverdin reductase (BLVR; EC 1.3.1.24); assignment of BLVR to the p14 leads to cen region of human chromosome 7 in mouse-human somatic cell hybrids.
Biochemical genetics 1983;21(1-2):123-33.
1981: H Mukhtar; C E Zoetemelk; A J Baars; Juul Wijnen; L M Blankenstein-Wijnen; P Meera Khan; D D Breimer
Glutathione S-transferase activity in human fetal and adult tissues.
Pharmacology 1981;22(5):322-9.