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Irina Gorshkova

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Andreas K Kateifides; Angeliki Chroni; Adelina Duka; Irina N Gorshkova; Dimitris Kardassis; Vassilis I Zannis
Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.
Irina N Gorshkova; David Atkinson
Enhanced binding of apolipoprotein A-I variants associated with hypertriglyceridemia to triglyceride-rich particles.
Irina N Gorshkova; Kyriakos E Kypreos; Donald L Gantz; Vassilis I Zannis; David Atkinson
Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia.

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All Publications

2011: Andreas K Kateifides; Angeliki Chroni; Adelina Duka; Irina N Gorshkova; Dimitris Kardassis; Vassilis I Zannis
Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.
Journal of lipid research 2011;52(7):1363-72.
2011: Irina N Gorshkova; David Atkinson
Enhanced binding of apolipoprotein A-I variants associated with hypertriglyceridemia to triglyceride-rich particles.
Biochemistry 2011;50(12):2040-7.
2008: Irina N Gorshkova; Kyriakos E Kypreos; Donald L Gantz; Vassilis I Zannis; David Atkinson
Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia.
Biochemistry 2008;47(47):12644-54.
2006: Irina N Gorshkova; Tong Liu; Horng-Yuan Kan; Angeliki Chroni; Vassilis I Zannis; David Atkinson
Structure and stability of apolipoprotein a-I in solution and in discoidal high-density lipoprotein probed by double charge ablation and deletion mutation.
Biochemistry 2006;45(4):1242-54.
2004: Angeliki Chroni; Horng-Yuan Kan; Kyriakos E Kypreos; Irina N Gorshkova; Adelina Shkodrani; Vassilis I Zannis
Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein A-I (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce severe hypertriglyceridemia in apoA-I-deficient mice.
Biochemistry 2004;43(32):10442-57.
2003: Angeliki Chroni; Tong Liu; Irina N Gorshkova; Horng-Yuan Kan; Yoshinari Uehara; Arnold von Eckardstein; Vassilis I Zannis
The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo.
The Journal of biological chemistry 2003;278(9):6719-30.
2002: Irina N Gorshkova; Tong Liu; Vassilis I Zannis; David Atkinson
Lipid-free structure and stability of apolipoprotein A-I: probing the central region by mutation.
Biochemistry 2002;41(33):10529-39.
2000: Irina N Gorshkova; KN Liadaki; Olga Gursky; David Atkinson; Vassilis I Zannis
Probing the lipid-free structure and stability of apolipoprotein A-I by mutation.
Biochemistry 2000;39(51):15910-9.
1996: Irina N Gorshkova; Mario Menschikowski; W Jaross
Alterations in the physiochemical characteristics of low and high density lipoproteins after lipolysis with phospholipase A2. A spin-label study.
Biochimica et biophysica acta 1996;1300(2):103-13.
1996: Irina N Gorshkova; N G Kiseleva; N M Akhmedzhanov; NV Perova
[Effect of enduracin on the activity of a cholesterol ester transfer protein in blood plasma of people with hypercholesteremia].
Biulleten' eksperimental'noĭ biologii i meditsiny 1996;121(2):185-7.
1991: Irina N Gorshkova; G N Shchukina; AD Morozkin; M A Sokolova; E K Ruuge; N V Perova; E I Sokolov; R G Oganov
[Changes in the physicochemical characteristics of low-density lipoproteins following a single fat load].
Fiziologiia cheloveka 1991;17(6):119-25.
1990: A P Sediuk; Iu A Shakhov; V V Konstantinov; Irina N Gorshkova; M A Sokolova
[Changes in high density lipoprotein subfractions during interaction with fibroblasts and hepatoma G-2 in various dyslipidemias].
Voprosy medit͡sinskoĭ khimii 1990;36(5):48-53.
1990: Iu A Shakhov; I E Petrichenko; Irina N Gorshkova; N V Perova; R G Oganov
[Low-density lipoproteins decrease cell sensitivity to glucocorticoids].
Doklady Akademii nauk SSSR 1990;313(4):1003-6.
1988: Irina N Gorshkova; E A Noeva; V A Polesskiĭ; N V Perova; E K Ruuge
[A study of thermoinduced changes in human high-density lipoproteins in hypo-alpha-lipoproteinemia and ischemic heart disease by the spin label method].
Voprosy medit͡sinskoĭ khimii 1988;34(3):85-90.
1988: Irina N Gorshkova; N V Medvedeva; AD Morozkin; I V Fuki; N N Gorchakova
[Physico-chemical and functional characteristics of a subfraction of low-density lipoproteins isolated by ion-exchange column chromatography].
Biokhimii͡a (Moscow, Russia) 1988;53(4):687-93.
1983: S El'-Karadagi; E K Ruuge; V A Tverdislov; V I Iuzhakov; Irina N Gorshkova
[Localization of tryptophanyl residues in the low-density lipoproteins of human plasma based on fluorescence paramagnetic quenching data].
Biofizika 1983;28(2):343-4.
1983: M L Belaia; S El'-Karadagi; Irina N Gorshkova; V A Tverdislov
[Interaction between plasma lipoproteins and bilayer lipid membranes. The role of surface charge].
Biofizika 1983;28(2):254-9.
1982: Irina N Gorshkova; N V Perova; E K Ruuge; N M Lobova; V A Polesskiĭ
[Spin label analysis of subclasses of high density lipoproteins].
Voprosy medit͡sinskoĭ khimii 1982;28(1):106-13.
1979: I G Kharitonenkov; Irina N Gorshkova; E K Ruuge
[Covalent fixation of a spin label containing a free amino group on protein molecules].
Biofizika 1979;24(5):927-9.