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Gareth Bond

Research Profile

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Kristiaan Lenos; Kirsten Lodder; Emmanouela Repapi; Helge Taubert; Amina Teunisse; Peter Wuerl; Frank Bartel; Gareth Bond; Anne-Marie Cleton-Jansen; Anna M Grawenda; Lukasz F Grochola; Pancras C W Hogendoorn; Marieke L Kuijjer; Aart G Jochemsen
Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.
Karen S Yee; Helge Taubert; Peter Wurl; Elisabeth E Bond; Gareth Bond; Anna Grawenda; Lukasz Grochola; Garth Hamilton; Eric O'Neill
A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.
Alexei Vazquez; Diptee Kulkarni; Lukasz F Grochola; Gareth Bond; Nicola Barnard; Deborah Toppmeyer; Arnold J Levine; Kim M Hirshfield
A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.

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All Publications

2012: Kristiaan Lenos; Kirsten Lodder; Emmanouela Repapi; Helge Taubert; Amina Teunisse; Peter Wuerl; Frank Bartel; Gareth Bond; Anne-Marie Cleton-Jansen; Anna M Grawenda; Lukasz F Grochola; Pancras C W Hogendoorn; Marieke L Kuijjer; Aart G Jochemsen
Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.
Cancer research 2012;72(16):4074-84.
2012: Karen S Yee; Helge Taubert; Peter Wurl; Elisabeth E Bond; Gareth Bond; Anna Grawenda; Lukasz Grochola; Garth Hamilton; Eric O'Neill
A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.
Cancer research 2012;72(9):2206-17.
2011: Alexei Vazquez; Diptee Kulkarni; Lukasz F Grochola; Gareth Bond; Nicola Barnard; Deborah Toppmeyer; Arnold J Levine; Kim M Hirshfield
A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.
International journal of cancer. Journal international du cancer 2011;128(10):2335-43.
2010: Sean M Post; Alfonso Quintás-Cardama; Vinod Pant; Tomoo Iwakuma; Amir Hamir; James G Jackson; Daniela R Maccio; Gareth Bond; David G Johnson; Arnold J Levine; Guillermina Lozano
A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.
Cancer cell 2010;18(3):220-30.
2010: Lukasz F Grochola; Jorge Zeron-Medina; Sophie Mériaux; Gareth Bond
Single-nucleotide polymorphisms in the p53 signaling pathway.
Cold Spring Harbor perspectives in biology 2010;2(5):a001032.
2010: Alexei Vazquez; Lukasz F Grochola; Elisabeth E Bond; Arnold J Levine; Helge Taubert; Thomas H Müller; Peter Würl; Gareth Bond
Chemosensitivity profiles identify polymorphisms in the p53 network genes 14-3-3tau and CD44 that affect sarcoma incidence and survival.
Cancer research 2010;70(1):172-80.
2010: Lukasz F Grochola; Thomas H Müller; Gareth Bond; Helge Taubert; Andrej Udelnow; Peter Würl
MDM2 SNP309 associates with accelerated pancreatic adenocarcinoma formation.
Pancreas 2010;39(1):76-80.
2009: Lukasz F Grochola; Alexei Vazquez; Elisabeth E Bond; Peter Würl; Helge Taubert; Thomas H Müller; Arnold J Levine; Gareth Bond
Recent natural selection identifies a genetic variant in a regulatory subunit of protein phosphatase 2A that associates with altered cancer risk and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6301-8.
2009: Gurinder Singh Atwal; Tomas Kirchhoff; Elisabeth E Bond; Marco Montagna; Marco Monagna; Chiara Menin; Roberta Bertorelle; Maria Chiara Scaini; Frank Bartel; Anja Böhnke; Christina Pempe; Elise Gradhand; Steffen Hauptmann; Kenneth Offit; Arnold J Levine; Gareth Bond
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10236-41.
2008: Alexei Vazquez; Elisabeth E Bond; Arnold J Levine; Gareth Bond
The genetics of the p53 pathway, apoptosis and cancer therapy.
Nature reviews. Drug discovery 2008;7(12):979-87.
2008: Gurinder Singh Atwal; Raúl Rabadán; Guillermina Lozano; Louise C Strong; Mariëlle W G Ruijs; Marjanka K Schmidt; Laura J van't Veer; Heli Nevanlinna; Johanna Tommiska; Kristiina Aittomäki; Gaelle Bougeard; Thierry Frebourg; Arnold J Levine; Gareth Bond
An information-theoretic analysis of genetics, gender and age in cancer patients.
PloS one 2008;3(4):e1951.
2007: Gurinder Singh Atwal; Gareth Bond; Sally Metsuyanim; Moshe Papa; Eitan Friedman; Tal Distelman-Menachem; Edna Ben-Asher; Doron Lancet; David A Ross; John J Sninsky; Tomas J White; Arnold J Levine; Ronit Yarden
Haplotype structure and selection of the MDM2 oncogene in humans.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4524-9.
2007: Gareth Bond; Arnold J Levine
A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans.
Oncogene 2007;26(9):1317-23.
2006: Gareth Bond; Chiara Menin; Roberta Bertorelle; Pia Alhopuro; Lauri A Aaltonen; Arnold J Levine
MDM2 SNP309 accelerates colorectal tumour formation in women.
Journal of medical genetics 2006;43(12):950-2.
2006: Gareth Bond; Kim M Hirshfield; Tomas Kirchhoff; Gabriella Alexe; Elisabeth E Bond; Harlan Robins; Frank Bartel; Helge Taubert; Peter Wuerl; William N Hait; Deborah Toppmeyer; Kenneth Offit; Arnold J Levine
MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner.
Cancer research 2006;66(10):5104-10.
2005: Nicoleta C Arva; Tamara R Gopen; Kathryn E Talbott; Latoya E Campbell; Agustin Chicas; David E White; Gareth Bond; Arnold J Levine; Jill Bargonetti
A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells.
The Journal of biological chemistry 2005;280(29):26776-87.
2005: Gareth Bond; Wenwei Hu; Arnold J Levine
A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect.
Cancer research 2005;65(13):5481-4.
2005: Gareth Bond; Wenwei Hu; Arnold J Levine
MDM2 is a central node in the p53 pathway: 12 years and counting.
Current cancer drug targets 2005;5(1):3-8.
2005: Sandra Harris; G Gil; W Hu; H Robins; Elisabeth E Bond; Kim M Hirshfield; Z Feng; X Yu; A K Teresky; Gareth Bond; Arnold J Levine
Single-nucleotide polymorphisms in the p53 pathway.
Cold Spring Harbor symposia on quantitative biology 2005;70():111-9.
2004: Gareth Bond; Wenwei Hu; Elisabeth E Bond; Harlan Robins; Stuart G Lutzker; Nicoleta C Arva; Jill Bargonetti; Frank Bartel; Helge Taubert; Peter Wuerl; Kenan Onel; Linwah Yip; Shih-Jen Hwang; Louise C Strong; Guillermina Lozano; Arnold J Levine
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.
Cell 2004;119(5):591-602.
2001: Suzanne Topalian; Syuzo Kaneko; Monica I Gonzales; Gareth Bond; Yvona Ward; J L Manley
Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors.
Molecular and cellular biology 2001;21(16):5614-23.
2000: Gareth Bond; Carol Prives; James L Manley
Poly(A) polymerase phosphorylation is dependent on novel interactions with cyclins.
Molecular and cellular biology 2000;20(14):5310-20.