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Christophe Cavin

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Maricel Marin-Kuan; Christophe Cavin; Thierry Delatour; Veronika A Ehrlich; Benoît Schilter
Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a.
Mathieu Renouf; Philippe A Guy; Cynthia Marmet; Karin Longet; Anne-Lise Fraering; Julie Moulin; Denis Barron; Fabiola Dionisi; Christophe Cavin; Heike Steiling; Gary Williamson
Plasma appearance and correlation between coffee and green tea metabolites in human subjects.
Christine Hoelzl; Siegfried Knasmüller; Karl-Heinz Wagner; Leonilla Elbling; Wolfgang Huber; Nina Kager; Franziska Ferk; Veronika A Ehrlich; Armen K Nersesyan; Oliver Neubauer; Aurélien Desmarchelier; Maricel Marin-Kuan; Thierry Delatour; Clotilde Verguet; Claudine Bezençon; Amélie Besson; Dominik Grathwohl; Tatjana Simic; Michael Kundi; Benoît Schilter; Christophe Cavin
Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules.

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All Publications

2011: Maricel Marin-Kuan; Christophe Cavin; Thierry Delatour; Veronika A Ehrlich; Benoît Schilter
Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a.
Journal of toxicology 2011;2011():645361.
2010: Mathieu Renouf; Philippe A Guy; Cynthia Marmet; Karin Longet; Anne-Lise Fraering; Julie Moulin; Denis Barron; Fabiola Dionisi; Christophe Cavin; Heike Steiling; Gary Williamson
Plasma appearance and correlation between coffee and green tea metabolites in human subjects.
The British journal of nutrition 2010;104(11):1635-40.
2010: Christine Hoelzl; Siegfried Knasmüller; Karl-Heinz Wagner; Leonilla Elbling; Wolfgang Huber; Nina Kager; Franziska Ferk; Veronika A Ehrlich; Armen K Nersesyan; Oliver Neubauer; Aurélien Desmarchelier; Maricel Marin-Kuan; Thierry Delatour; Clotilde Verguet; Claudine Bezençon; Amélie Besson; Dominik Grathwohl; Tatjana Simic; Michael Kundi; Benoît Schilter; Christophe Cavin
Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules.
Molecular nutrition & food research 2010;54(12):1722-33.
2010: Miroslav Mišík; Christine Hoelzl; Karl-Heinz Wagner; Christophe Cavin; Beate Moser; Michael Kundi; Tanja Simic; Leonilla Elbling; Nina Kager; Franziska Ferk; Veronika A Ehrlich; Armen K Nersesyan; Maria Dušinská; Benoît Schilter; Siegfried Knasmüller
Impact of paper filtered coffee on oxidative DNA-damage: results of a clinical trial.
Mutation research 2010;692(1-2):42-8.
2010: Mathieu Renouf; Philippe A Guy; Cynthia Marmet; Anne-Lise Fraering; Karin Longet; Julie Moulin; Marc Enslen; Denis Barron; Fabiola Dionisi; Christophe Cavin; Gary Williamson; Heike Steiling
Measurement of caffeic and ferulic acid equivalents in plasma after coffee consumption: small intestine and colon are key sites for coffee metabolism.
Molecular nutrition & food research 2010;54(6):760-6.
2010: Mathieu Renouf; Cynthia Marmet; Philippe A Guy; Anne-Lise Fraering; Karin Longet; Julie Moulin; Marc Enslen; Denis Barron; Christophe Cavin; Fabiola Dionisi; Francois-Pierre Martin; Sunil Kochhar; Heike Steiling; Gary Williamson
Nondairy creamer, but not milk, delays the appearance of coffee phenolic acid equivalents in human plasma.
The Journal of nutrition 2010;140(2):259-63.
2009: Philippe A Guy; Mathieu Renouf; Denis Barron; Christophe Cavin; Fabiola Dionisi; Sunil Kochhar; Francois-Pierre Martin; Gary Williamson; Heike Steiling
Quantitative analysis of plasma caffeic and ferulic acid equivalents by liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(31):3965-74.
2009: Christophe Cavin; Thierry Delatour; Maricel Marin-Kuan; François Fenaille; Daisy Holzhäuser; Gabrièla Guignard; Claudine Bezençon; Dominique Piguet; Véronique Parisod; Janique Richoz-Payot; Benoît Schilter
Ochratoxin A-mediated DNA and protein damage: roles of nitrosative and oxidative stresses.
Toxicological sciences : an official journal of the Society of Toxicology 2009;110(1):84-94.
2009: Muriel Jaquet; Isabelle Rochat; Julie Moulin; Christophe Cavin; Rodrigo Bibiloni
Impact of coffee consumption on the gut microbiota: a human volunteer study.
International journal of food microbiology 2009;130(2):117-21.
2008: Christophe Cavin; Maricel Marin-Kuan; S Langouët; Claudine Bezençon; G Guignard; C Verguet; D Piguet; D Holzhäuser; R Cornaz; Benoît Schilter
Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1239-48.
2008: Larry G Higgins; Christophe Cavin; Ken Itoh; Masayuki Yamamoto; John D Hayes
Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
Toxicology and applied pharmacology 2008;226(3):328-37.
2007: Maricel Marin-Kuan; Sandra Nestler; C Verguet; Claudine Bezençon; D Piguet; Thierry Delatour; Peter G Mantle; Christophe Cavin; Benoît Schilter
MAPK-ERK activation in kidney of male rats chronically fed ochratoxin A at a dose causing a significant incidence of renal carcinoma.
Toxicology and applied pharmacology 2007;224(2):174-81.
2007: Julia Bichler; Christophe Cavin; T Simic; Asima Chakraborty; Franziska Ferk; Christine Hoelzl; Rolf Schulte-Hermann; Michael Kundi; Gerald Haidinger; K Angelis; Siegfried Knasmüller
Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(8):1428-36.
2007: Christophe Cavin; Thierry Delatour; Maricel Marin-Kuan; Daisy Holzhäuser; Larry Higgins; Claudine Bezençon; Gabriela Guignard; Sylviane Junod; Janique Richoz-Payot; Eric Gremaud; John D Hayes; Sandra Nestler; Peter G Mantle; Benoît Schilter
Reduction in antioxidant defenses may contribute to ochratoxin A toxicity and carcinogenicity.
Toxicological sciences : an official journal of the Society of Toxicology 2007;96(1):30-9.
2006: Maricel Marin-Kuan; Sandra Nestler; C Verguet; Claudine Bezençon; D Piguet; R Mansourian; JA Holzwarth; Martin Grigorov; Thierry Delatour; Peter G Mantle; Christophe Cavin; Benoît Schilter
A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(1):120-34.
2005: Herta Steinkellner; Christine Hoelzl; Maria Uhl; Christophe Cavin; Gerald Haidinger; Andrea Gsur; Rainer Schmid; Michael Kundi; Julia Bichler; Siegfried Knasmüller
Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials.
Mutation research 2005;591(1-2):264-75.
2005: Bernhard J Majer; E Hofer; Christophe Cavin; Evelyne Lhoste; Maria Uhl; Hansruedi Glatt; Walter Meinl; Siegfried Knasmüller
Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(3):433-41.
2005: Christophe Cavin; M Delannoy; A Malnoe; E Debefve; André Touché; Didier Courtois; Benoît Schilter
Inhibition of the expression and activity of cyclooxygenase-2 by chicory extract.
Biochemical and biophysical research communications 2005;327(3):742-9.
2005: Benoît Schilter; Maricel Marin-Kuan; Thierry Delatour; Sandra Nestler; Peter G Mantle; Christophe Cavin
Ochratoxin A: potential epigenetic mechanisms of toxicity and carcinogenicity.
Food additives and contaminants 2005;22 Suppl 1():88-93.
2004: Siegfried Knasmüller; Christophe Cavin; Asima Chakraborty; Firouz Darroudi; Bernhard J Majer; Wolfgang W Huber; Veronika A Ehrlich
Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment.
Nutrition and cancer 2004;50(2):190-7.
2003: Christophe Cavin; C Bezencon; G Guignard; Benoît Schilter
Coffee diterpenes prevent benzo[a]pyrene genotoxicity in rat and human culture systems.
Biochemical and biophysical research communications 2003;306(2):488-95.
2002: Christophe Cavin; D Holzhaeuser; Gerlinde Scharf; Anne Constable; Wolfgang W Huber; Benoît Schilter
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(8):1155-63.
2001: Christophe Cavin; K Mace; Elizabeth A Offord; Benoît Schilter
Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(6):549-56.
2001: Michael McMahon; Ken Itoh; Masayuki Yamamoto; Simon A Chanas; Colin Henderson; Lesley I McLellan; C Roland Wolf; Christophe Cavin; John D Hayes
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
Cancer research 2001;61(8):3299-307.
1998: Christophe Cavin; D Holzhäuser; Anne Constable; AC Huggett; Benoît Schilter
The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism.
Carcinogenesis 1998;19(8):1369-75.