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Xavier Cayla

Research Profile

Chemicals & Drugs

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Publications

TOP 3
A Galioot; A N Godet; V Maire; B Baron; Xavier Cayla; Patrick England; Pierre B Falanga; Alphonse Garcia
Transducing properties of a pre-structured α-helical DPT-peptide containing a short canine adenovirus type 2 E4orf4 PP2A1-binding sequence.
Julien Guergnon; Angélique N Godet; Xavier Cayla; Jean-Hervé Colle; Pierre B Falanga; Amandine Galioot; Alphonse Garcia
PP2A targeting by viral proteins: a widespread biological strategy from DNA/RNA tumor viruses to HIV-1.
Angélique N Godet; Julien Guergnon; Amélie Croset; Xavier Cayla; Pierre Barthélemy Falanga; Jean-Hervé Colle; Alphonse Garcia
PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins.

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All Publications

2013: A Galioot; A N Godet; V Maire; B Baron; Xavier Cayla; Patrick England; Pierre B Falanga; Alphonse Garcia
Transducing properties of a pre-structured α-helical DPT-peptide containing a short canine adenovirus type 2 E4orf4 PP2A1-binding sequence.
Biochimica et biophysica acta 2013;1830(6):3578-83.
2011: Julien Guergnon; Angélique N Godet; Xavier Cayla; Jean-Hervé Colle; Pierre B Falanga; Amandine Galioot; Alphonse Garcia
PP2A targeting by viral proteins: a widespread biological strategy from DNA/RNA tumor viruses to HIV-1.
Biochimica et biophysica acta 2011;1812(11):1498-507.
2010: Angélique N Godet; Julien Guergnon; Amélie Croset; Xavier Cayla; Pierre Barthélemy Falanga; Jean-Hervé Colle; Alphonse Garcia
PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins.
PloS one 2010;5(11):e13760.
2009: Gaelle Jan; Violaine Delorme; Nehmé Saksouk; Marie Abrivard; Virginie Gonzalez; Xavier Cayla; Mohamed-Ali Hakimi; Isabelle Tardieux
A Toxoplasma type 2C serine-threonine phosphatase is involved in parasite growth in the mammalian host cell.
Microbes and infection / Institut Pasteur 2009;11(12):935-45.
2007: Gaelle Jan; Violaine Delorme; violaine david; Celine Revenu; Angelita Rebollo; Xavier Cayla; Isabelle Tardieux
The toxofilin-actin-PP2C complex of Toxoplasma: identification of interacting domains.
The Biochemical journal 2007;401(3):711-9.
2006: Frédéric Dessauge; Xavier Cayla; Juan Pablo Albar; Aarne Fleischer; Ata Ghadiri; Marianne Duhamel; Angelita Rebollo
Identification of PP1alpha as a caspase-9 regulator in IL-2 deprivation-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2441-51.
2006: Julien Guergnon; Frédéric Dessauge; François Traincard; Xavier Cayla; Angelita Rebollo; Pierre-Etienne Bost; Gordon Langsley; Alphonse Garcia
A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes.
Apoptosis : an international journal on programmed cell death 2006;11(8):1263-73.
2006: Julien Guergnon; Frédéric Dessauge; victoria dominguez; Jean Viallet; Serge Bonnefoy; Victor Jose Yuste; Odile Mercereau-Puijalon; Xavier Cayla; Angelita Rebollo; Santos A Susin; Pierre-Etienne Bost; Alphonse Garcia
Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology.
Molecular pharmacology 2006;69(4):1115-24.
2004: Aarne Fleischer; Ata Ghadiri; Frédéric Dessauge; Marianne Duhamel; Xavier Cayla; Alphonse Garcia; Angelita Rebollo
Bad-dependent rafts alteration is a consequence of an early intracellular signal triggered by interleukin-4 deprivation.
Molecular cancer research : MCR 2004;2(12):674-84.
2004: Alphonse Garcia; Xavier Cayla; Bernard Caudron; Eric Deveaud; Fernando Roncal; Angelita Rebollo
New insights in protein phosphorylation: a signature for protein phosphatase 1 interacting proteins.
Comptes rendus biologies 2004;327(2):93-7.
2003: Alphonse Garcia; Xavier Cayla; Aarne Fleischer; Julien Guergnon; Fernando Alvarez-Franco Cañas; Maria Paz Rebollo; Fernando Roncal; Angelita Rebollo
Rafts: a simple way to control apoptosis by subcellular redistribution.
Biochimie 2003;85(8):727-31.
2003: Alphonse Garcia; Xavier Cayla; Julien Guergnon; Frédéric Dessauge; Véronique Hospital; Maria Paz Rebollo; Aarne Fleischer; Angelita Rebollo
Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis.
Biochimie 2003;85(8):721-6.
2003: Violaine Delorme; Xavier Cayla; Grazyna Faure; Alphonse Garcia; Isabelle Tardieux
Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin.
Molecular biology of the cell 2003;14(5):1900-12.
2002: Veronique De Smedt; Robert Poulhe; Xavier Cayla; Frédéric Dessauge; Anthi Karaiskou; Catherine Jessus; René Ozon
Thr-161 phosphorylation of monomeric Cdc2. Regulation by protein phosphatase 2C in Xenopus oocytes.
The Journal of biological chemistry 2002;277(32):28592-600.
2002: Verónica Ayllón; Xavier Cayla; Alphonse García; Aarne Fleischer; Angelita Rebollo
The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad.
European journal of immunology 2002;32(7):1847-55.
2002: Verónica Ayllón; Aarne Fleischer; Xavier Cayla; Alphonse García; Angelita Rebollo
Segregation of Bad from lipid rafts is implicated in the induction of apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3387-93.
2002: Violaine Delorme; Alphonse Garcia; Xavier Cayla; Isabelle Tardieux
A role for Toxoplasma gondii type 1 ser/thr protein phosphatase in host cell invasion.
Microbes and infection / Institut Pasteur 2002;4(3):271-8.
2001: Verónica Ayllón; Xavier Cayla; Alphonse García; Fernando Roncal; R Fernández; Juan Pablo Albar; Carlos Martínez; Angelita Rebollo
Bcl-2 targets protein phosphatase 1 alpha to Bad.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7345-52.
2000: Xavier Cayla; Alphonse Garcia; Martin Baumgartner; René Ozon; Gordon Langsley
A Theileria parva type 1 protein phosphatase activity.
Molecular and biochemical parasitology 2000;110(1):161-6.
2000: Verónica Ayllón; Carlos Martínez-A; Alphonse García; Xavier Cayla; Angelita Rebollo
Protein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis.
The EMBO journal 2000;19(10):2237-46.
2000: Alphonse Garcia; Xavier Cayla; E Sontag
Protein phosphatase 2A: a definite player in viral and parasitic regulation.
Microbes and infection / Institut Pasteur 2000;2(4):401-7.
1999: Alphonse Garcia; Xavier Cayla; S Barik; Gordon Langsley
A family of PP2 phosphatases in Plasmodium falciparum and parasitic protozoa.
Parasitology today (Personal ed.) 1999;15(3):90-2.
1998: A Karaïskou; Xavier Cayla; Olivier Haccard; Catherine Jessus; René Ozon
MPF amplification in Xenopus oocyte extracts depends on a two-step activation of cdc25 phosphatase.
Experimental cell research 1998;244(2):491-500.
1997: H Y Tung; H De Rocquigny; L J Zhao; Xavier Cayla; B P Roques; René Ozon
Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.
FEBS letters 1997;401(2-3):197-201.
1995: Christine Van Hoof; F Ingels; Xavier Cayla; Ilse Stevens; Wilfried Merlevede; Jozef Goris
Molecular cloning and developmental regulation of expression of two isoforms of the catalytic subunit of protein phosphatase 2A from Xenopus laevis.
Biochemical and biophysical research communications 1995;215(2):666-73.
1995: Christine Van Hoof; M S Aly; A Garcia; Xavier Cayla; Jean-Jacques Cassiman; Wilfried Merlevede; Jozef Goris
Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A.
Genomics 1995;28(2):261-72.
1995: M Bosch; Xavier Cayla; Christine Van Hoof; Brian A Hemmings; René Ozon; Wilfried Merlevede; Jozef Goris
The PR55 and PR65 subunits of protein phosphatase 2A from Xenopus laevis. molecular cloning and developmental regulation of expression.
European journal of biochemistry / FEBS 1995;230(3):1037-45.
1994: Christine Van Hoof; Xavier Cayla; M Bosch; Wilfried Merlevede; Jozef Goris
The phosphotyrosyl phosphatase activator of protein phosphatase 2A. A novel purification method, immunological and enzymic characterization.
European journal of biochemistry / FEBS 1994;226(3):899-907.
1994: Xavier Cayla; Christine Van Hoof; M Bosch; Etienne Waelkens; Joël Vandekerckhove; Ben Peeters; Wilfried Merlevede; Jozef Goris
Molecular cloning, expression, and characterization of PTPA, a protein that activates the tyrosyl phosphatase activity of protein phosphatase 2A.
The Journal of biological chemistry 1994;269(22):15668-75.
1993: Xavier Cayla; K Ballmer-Hofer; Wilfried Merlevede; Jozef Goris
Phosphatase 2A associated with polyomavirus small-T or middle-T antigen is an okadaic acid-sensitive tyrosyl phosphatase.
European journal of biochemistry / FEBS 1993;214(1):281-6.
1990: Olivier Haccard; Catherine Jessus; Xavier Cayla; Jozef Goris; Wilfried Merlevede; René Ozon
In vivo activation of a microtubule-associated protein kinase during meiotic maturation of the Xenopus oocyte.
European journal of biochemistry / FEBS 1990;192(3):633-42.
1990: Xavier Cayla; Jozef Goris; J Hermann; P Hendrix; René Ozon; Wilfried Merlevede
Isolation and characterization of a tyrosyl phosphatase activator from rabbit skeletal muscle and Xenopus laevis oocytes.
Biochemistry 1990;29(3):658-67.
1990: Xavier Cayla; Jozef Goris; J Hermann; Catherine Jessus; P Hendrix; Wilfried Merlevede
Phosphotyrosyl phosphatase activity of the polycation-stimulated protein phosphatases and involvement of dephosphorylation in cell cycle regulation.
Advances in enzyme regulation 1990;30():265-85.
1989: Catherine Jessus; Jozef Goris; S Staquet; Xavier Cayla; René Ozon; Wilfried Merlevede
Identification of the ATP + Mg-dependent and polycation-stimulated protein phosphatases in the germinal vesicle of the Xenopus oocyte.
The Biochemical journal 1989;260(1):45-51.
1989: Catherine Jessus; Jozef Goris; Xavier Cayla; J Hermann; P Hendrix; René Ozon; Wilfried Merlevede
Tubulin and MAP2 regulate the PCSL phosphatase activity. A possible new role for microtubular proteins.
European journal of biochemistry / FEBS 1989;180(1):15-22.
1988: J Hermann; Xavier Cayla; K Dumortier; Jozef Goris; René Ozon; Wilfried Merlevede
Modulation of the substrate specificity of the polycation-stimulated protein phosphatase from Xenopus laevis oocytes.
European journal of biochemistry / FEBS 1988;173(1):17-25.
1988: Odile Mulner-Lorillon; J Marot; Xavier Cayla; R Pouhle; Robert Bellé
Purification and characterization of a casein-kinase-II-type enzyme from Xenopus laevis ovary. Biological effects on the meiotic cell division of full-grown oocyte.
European journal of biochemistry / FEBS 1988;171(1-2):107-17.