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Ludmila Prokunina-Olsson

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Ludmila Prokunina-Olsson; Barbara Rehermann; Faruk Sheikh; Wei Tang; McAnthony Tarway; David L Thomas; Heiyoung Park; Ruth M Pfeiffer; Patricia Porter-Gill; Jacquie Astemborski; Herbert L Bonkovsky; Nathan Brand; Sabrina Chen; Harold Dickensheets; Raymond P Donnelly; Brian R Edlin; Dianna Hergott; Charles D Howell; Indu kohaar; Luyang Liu; Timothy R Morgan; Brian Muchmore; Adam Mumy; Thomas R O'Brien
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus.
Indu kohaar; Petra Lenz; Lee E Moore; Adam Mumy; Patricia Porter-Gill; Andrea B Apolo; Dalsu Baris; Yi-Ping Fu; Stephen M Hewitt; Alison Johnson; Michael Jones; Masatoshi Kida; Nathaniel Rothman; Alan R Schned; Molly Schwenn; Debra T Silverman; Wei Tang; Kris Ylaya; Ludmila Prokunina-Olsson
Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer.
Heiyoung Park; Ludmila Prokunina-Olsson; Elisavet Serti; Stefania Capone; Onyinyechi Eke; Antonella Folgori; Brian Muchmore; Barbara Rehermann
IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection.

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All Publications

2013: Ludmila Prokunina-Olsson; Barbara Rehermann; Faruk Sheikh; Wei Tang; McAnthony Tarway; David L Thomas; Heiyoung Park; Ruth M Pfeiffer; Patricia Porter-Gill; Jacquie Astemborski; Herbert L Bonkovsky; Nathan Brand; Sabrina Chen; Harold Dickensheets; Raymond P Donnelly; Brian R Edlin; Dianna Hergott; Charles D Howell; Indu kohaar; Luyang Liu; Timothy R Morgan; Brian Muchmore; Adam Mumy; Thomas R O'Brien
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus.
Nature genetics 2013;45(2):164-71.
2013: Indu kohaar; Petra Lenz; Lee E Moore; Adam Mumy; Patricia Porter-Gill; Andrea B Apolo; Dalsu Baris; Yi-Ping Fu; Stephen M Hewitt; Alison Johnson; Michael Jones; Masatoshi Kida; Nathaniel Rothman; Alan R Schned; Molly Schwenn; Debra T Silverman; Wei Tang; Kris Ylaya; Ludmila Prokunina-Olsson
Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer.
Journal of the National Cancer Institute 2013;105(1):69-73.
2012: Heiyoung Park; Ludmila Prokunina-Olsson; Elisavet Serti; Stefania Capone; Onyinyechi Eke; Antonella Folgori; Brian Muchmore; Barbara Rehermann
IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2012;56(6):2060-70.
2011: Fatma M Shebl; Ruth M Pfeiffer; Ludmila Prokunina-Olsson; Dianna Buckett; Sabrina Chen; Myhanh Dotrang; Brian R Edlin; Brian Muchmore; Thomas R O'Brien
IL28B rs12979860 genotype and spontaneous clearance of hepatitis C virus in a multi-ethnic cohort of injection drug users: evidence for a supra-additive association.
The Journal of infectious diseases 2011;204(12):1843-7.
2011: Thomas R O'Brien; R M Pfeiffer; Indu kohaar; Dennis L Maeder; E E Schadt; M Yeager; Ludmila Prokunina-Olsson
Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver.
Genes and immunity 2011;12(6):428-33.
2011: Kerstin B Meyer; Martin O'Reilly; Patricia Porter-Gill; Radhika Prathalingam; Ludmila Prokunina-Olsson; Stefan Ambs; Jason Carroll; Maya Ghoussaini; Ana-Teresa Maia; Bruce A J Ponder
A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.
PLoS genetics 2011;7(7):e1002165.
2010: Nathaniel Rothman; Montserrat Garcia-Closas; Nilanjan Chatterjee; Antoni Picornell; Xifeng Wu; Jonine D Figueroa; Francisco X Real; David Van Den Berg; Giuseppe Matullo; Dalsu Baris; Michael Thun; Lambertus A Kiemeney; Paolo Vineis; Immaculata De Vivo; Demetrius Albanes; Mark P Purdue; Thorunn Rafnar; Michelle A T Hildebrandt; Anne E Kiltie; Olivier Cussenot; Klaus Golka; Rajiv Kumar; Jack A Taylor; Jose I Mayordomo; Kevin B Jacobs; Manolis Kogevinas; Amy Hutchinson; Zhaoming Wang; Yi-Ping Fu; Ludmila Prokunina-Olsson; Laurie Burdett; Meredith Yeager; William Wheeler; Adonina Tardón; Consol Serra; Alfredo Carrato; Reina García-Closas; Josep Lloreta; Alison Johnson; Molly Schwenn; Margaret R Karagas; Alan Schned; Gerald Andriole; Robert Grubb; Amanda Black; Eric J Jacobs; W Ryan Diver; Susan M Gapstur; Stephanie J Weinstein; Jarmo Virtamo; Victoria K Cortessis; Manuela Gago-Dominguez; Malcolm Pike; Mariana C Stern; Jian-Min Yuan; David J Hunter; Monica McGrath; Colin P Dinney; Bogdan Czerniak; Meng Chen; Hushan Yang; Sita H Vermeulen; Katja K Aben; J Alfred Witjes; Remco R Makkinje; Patrick Sulem; Soren Besenbacher; Kari Stefansson; Elio Riboli; Paul Brennan; Salvatore Panico; Carmen Navarro; Naomi E Allen; H Bas Bueno-de-Mesquita; Dimitrios Trichopoulos; Neil Caporaso; Maria Teresa Landi; Federico Canzian; Borje Ljungberg; Anne Tjonneland; Francoise Clavel-Chapelon; David T Bishop; Mark T W Teo; Margaret A Knowles; Simonetta Guarrera; Silvia Polidoro; Fulvio Ricceri; Carlotta Sacerdote; Alessandra Allione; Geraldine Cancel-Tassin; Silvia Selinski; Jan G Hengstler; Holger Dietrich; Tony Fletcher; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Sophia C E Bolick; Ashley Godfrey; Zongli Xu; José I Sanz-Velez; María D García-Prats; Manuel Sanchez; Gabriel Valdivia; Stefano Porru; Simone Benhamou; Robert N Hoover; Joseph F Fraumeni; Debra T Silverman; STEPHEN CHANOCK
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
Nature genetics 2010;42(11):978-84.
2010: C Cotsapas; Ludmila Prokunina-Olsson; C Welch; R Saxena; C Weaver; N Usher; C Guiducci; S Bonakdar; N Turner; B LaCroix; J L Hall
Expression analysis of loci associated with type 2 diabetes in human tissues.
Diabetologia 2010;53(11):2334-9.
2010: Fatma M Shebl; Dennis L Maeder; Yongwu Shao; Ludmila Prokunina-Olsson; Eric E Schadt; Thomas R O'Brien
In the absence of HCV infection, interferon stimulated gene expression in liver is not associated with IL28B genotype.
Gastroenterology 2010;139(4):1422-4.
2010: Kiran Musunuru; Alanna Strong; Maria Frank-Kamenetsky; Noemi E Lee; Tim Ahfeldt; Katherine V Sachs; Xiaoyu Li; Hui Li; Nicolas Kuperwasser; Vera M Ruda; James P Pirruccello; Brian Muchmore; Ludmila Prokunina-Olsson; Jennifer L Hall; Eric E Schadt; Carlos R Morales; Sissel Lund-Katz; Michael C Phillips; Jamie Wong; William Cantley; Timothy Racie; Kenechi G Ejebe; Marju Orho-Melander; Olle Melander; Victor Koteliansky; Kevin Fitzgerald; Ronald M Krauss; Chad A Cowan; Sekar Kathiresan; Daniel J Rader
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.
Nature 2010;466(7307):714-9.
2010: Indu kohaar; Alexander Ploss; Evgenia Korol; Kathy Mu; John W Schoggins; Thomas R O'Brien; Charles M Rice; Ludmila Prokunina-Olsson
Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry.
Journal of virology 2010;84(14):6987-94.
2010: Marie P Fogarty; Rui Xiao; Ludmila Prokunina-Olsson; Laura J Scott; Karen L Mohlke
Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK.
Human molecular genetics 2010;19(10):1921-9.
2010: Ludmila Prokunina-Olsson; Yi-Ping Fu; Wei Tang; Kevin B Jacobs; Richard B Hayes; Peter Kraft; Sonja I Berndt; Sholom Wacholder; Kai Yu; Amy Hutchinson; Heather Spencer Feigelson; Michael J Thun; W Ryan Diver; Demetrius Albanes; Jarmo Virtamo; Stephanie Weinstein; Fredrick R Schumacher; Geraldine Cancel-Tassin; Olivier Cussenot; Antoine Valeri; Gerald L Andriole; E David Crawford; Christopher A Haiman; Brian E Henderson; Laurence Kolonel; Loic Le Marchand; Afshan Siddiq; Elio Riboli; Ruth Travis; Rudolf Kaaks; William B Isaacs; Sarah D Isaacs; Henrik Grönberg; Fredrik Wiklund; Jianfeng Xu; Lars J Vatten; Kristian Hveem; Merethe Kumle; Margaret Tucker; Robert N Hoover; Joseph F Fraumeni; David J Hunter; Gilles Thomas; Nilanjan Chatterjee; STEPHEN CHANOCK; Meredith Yeager
Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(5):1349-55.
2010: Ludmila Prokunina-Olsson; J L Hall
Evidence for neuroendocrine function of a unique splicing form of TCF7L2 in human brain, islets and gut.
Diabetologia 2010;53(4):712-6.
2010: Ludmila Prokunina-Olsson; STEPHEN CHANOCK
Cancer sequencing gets a little more personal.
Science translational medicine 2010;2(20):20ps8.
2010: Yi-Ping Fu; Hege Edvardsen; Alpana Kaushiva; Juan P Arhancet; Tiffany M Howe; Indu kohaar; Patricia Porter-Gill; Anushi Shah; Hege Landmark-Høyvik; Sophie D Fosså; Stefan Ambs; Bjørn Naume; Anne-Lise Børresen-Dale; Vessela N Kristensen; Ludmila Prokunina-Olsson
NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.
Molecular cancer 2010;9():113.
2009: Ludmila Prokunina-Olsson; Cullan Welch; Ola Hansson; Neeta Adhikari; Laura J Scott; Nicolle Usher; Maurine Tong; Andrew Sprau; Amy Swift; Lori L Bonnycastle; Michael R Erdos; Zhi He; Richa Saxena; Brennan Harmon; Olga Kotova; Eric Hoffman; David Altshuler; Leif Groop; Michael Boehnke; Francis S Collins; Jennifer L Hall
Tissue-specific alternative splicing of TCF7L2.
Human molecular genetics 2009;18(20):3795-804.
2009: Gilles Thomas; Kevin B Jacobs; Peter Kraft; Meredith Yeager; Sholom Wacholder; David G Cox; Susan E Hankinson; Amy Hutchinson; Zhaoming Wang; Kai Yu; Nilanjan Chatterjee; Montserrat Garcia-Closas; Jesus Gonzalez-Bosquet; Ludmila Prokunina-Olsson; Nick Orr; Walter C Willett; GRaham Colditz; Regina G Ziegler; Christine D Berg; Saundra S Buys; Catherine A McCarty; Heather Spencer Feigelson; Eugenia E Calle; Michael J Thun; Ryan Diver; Ross Prentice; Rebecca Jackson; Charles Kooperberg; Rowan Chlebowski; Jolanta Lissowska; Beata Peplonska; Louise A Brinton; Alice Sigurdson; Michele Doody; Parveen Bhatti; Bruce H Alexander; Julie Buring; I-Min Lee; Lars J Vatten; Kristian Hveem; Merethe Kumle; Richard B Hayes; Margaret Tucker; Daniela S Gerhard; Joseph Fraumeni; Robert N Hoover; STEPHEN CHANOCK; David J Hunter
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).
Nature genetics 2009;41(5):579-84.
2009: Megan Y Dennis; Silvia Paracchini; Thomas Scerri; Ludmila Prokunina-Olsson; Julian C Knight; Richard Wade-Martins; Penny Coggill; Stephan Beck; Eric Green; Anthony P Monaco
A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
PLoS genetics 2009;5(3):e1000436.
2009: Ludmila Prokunina-Olsson; Jennifer L Hall
No effect of cancer-associated SNP rs6983267 in the 8q24 region on co-expression of MYC and TCF7L2 in normal colon tissue.
Molecular cancer 2009;8():96.
2009: Ludmila Prokunina-Olsson; Lee M Kaplan; Eric E Schadt; Francis S Collins
Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes.
PloS one 2009;4(9):e7231.
2009: Ellen L Goode; Csilla Szabo; Ludmila Prokunina-Olsson; Robert A Vierkant; Zachary S Fredericksen; Francis S Collins; Kristin L White; Mike Schmidt; Brooke L Fridley; Fergus J Couch
No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer.
BMC cancer 2009;9():312.
2008: Ilir Agalliu; Miia Suuriniemi; Ludmila Prokunina-Olsson; Bo Johanneson; Francis S Collins; Janet L Stanford; Elaine A Ostrander
Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study.
The Prostate 2008;68(7):740-7.
2007: Laura J Scott; Karen L Mohlke; Lori L Bonnycastle; Cristen J Willer; Yun Li; William L Duren; Michael R Erdos; Heather M Stringham; Peter S Chines; Anne U Jackson; Ludmila Prokunina-Olsson; Chia-Jen Ding; Amy J Swift; Narisu Narisu; Tianle Hu; Randall Pruim; Rui Xiao; Xiao-Yi Li; Karen N Conneely; Nancy L Riebow; Andrew G Sprau; Maurine Tong; Peggy P White; Kurt N Hetrick; Michael W Barnhart; Craig W Bark; Janet L Goldstein; Lee Watkins; Fang Xiang; Jouko Saramies; Thomas A Buchanan; Richard Watanabe; Timo T Valle; Leena Kinnunen; Goncalo Abecasis; Elizabeth W Pugh; Kimberly F Doheny; Richard N Bergman; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Science (New York, N.Y.) 2007;316(5829):1341-5.
2007: C M Thorburn; Ludmila Prokunina-Olsson; K A Sterba; Raymond F Lum; Michael F Seldin; Marta Eugenia ALARCON-RIQUELME; Lindsey A Criswell
Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort.
Genes and immunity 2007;8(4):279-87.
2006: Anna M Bennet; Marta E Alarcón-Riquelme; Björn Wiman; Ulf de Faire; Ludmila Prokunina-Olsson
Decreased risk for myocardial infarction and lower tumor necrosis factor-alpha levels in carriers of variants of the PDCD1 gene.
Human immunology 2006;67(9):700-5.
2005: Eric Kai-Pang Kong; Ludmila Prokunina-Olsson; Wong Wilfred; Chak Sing Lau; Tak Mao Chan; Marta E Alarcón-Riquelme; Yu-Lung Lau
A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese.
Arthritis and rheumatism 2005;52(4):1058-62.
2004: Ludmila Prokunina-Olsson; Leonid Padyukov; Anna Bennet; Ulf de Faire; Björn Wiman; Jonathan Prince; Lars Alfredsson; Lars Klareskog; Marta E Alarcón-Riquelme
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope.
Arthritis and rheumatism 2004;50(6):1770-3.
2004: Ludmila Prokunina-Olsson; Marta E Alarcón-Riquelme
Regulatory SNPs in complex diseases: their identification and functional validation.
Expert reviews in molecular medicine 2004;6(10):1-15.
2004: Ludmila Prokunina-Olsson; Marta Alarcon-Riquelme
The genetic basis of systemic lupus erythematosus--knowledge of today and thoughts for tomorrow.
Human molecular genetics 2004;13 Spec No 1():R143-8.
2004: Ludmila Prokunina-Olsson; Iva Gunnarsson; Gunnar Sturfelt; Lennart Truedsson; Victoria A Seligman; Jean L Olson; Michael F Seldin; Lindsey A Criswell; Marta E Alarcón-Riquelme
The systemic lupus erythematosus-associated PDCD1 polymorphism PD1.3A in lupus nephritis.
Arthritis and rheumatism 2004;50(1):327-8.
2003: Marta E Alarcón-Riquelme; Ludmila Prokunina-Olsson
Finding genes for SLE: complex interactions and complex populations.
Journal of autoimmunity 2003;21(2):117-20.
2002: Ludmila Prokunina-Olsson; Casimiro Castillejo-López; Fredrik Oberg; Iva Gunnarsson; Louise Berg; Veronica Magnusson; Anthony J Brookes; Dmitry Tentler; Helga Kristjansdóttir; Gerdur Gröndal; Anne Isine Bolstad; Elisabet Svenungsson; Ingrid Lundberg; Gunnar Sturfelt; Andreas Jönssen; Lennart Truedsson; Guadalupe Lima; Jorge Alcocer-Varela; Roland Jonsson; Ulf Gyllensten; John B Harley; Donato Alarcón-Segovia; Kristjan Steinsson; Marta E Alarcón-Riquelme
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans.
Nature genetics 2002;32(4):666-9.