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David Hill

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Xiaofeng Xin; Xinping Yang; Yingnan Zhang; Adenrele Akintobi; Charles Boone; Dryden Bouamalay; Aaron T Cheng; Jackie Cheng; Bridget Currell; David G Drubin; David Gfeller; Barth D Grant; Mark L Grimes; Ailan Guo; Tong Hao; David E Hill; Jingjing Li; Lianet Lopez; Adrien Lugari; Alevtina Pavlenco; Jean-François Rual; Kourosh Salehi-Ashtiani; Somasekar Seshagiri; Yun A Shen; Sachdev S Sidhu; Lin Sun; Raffi Tonikian; Marc Vidal; Gary D Bader
SH3 interactome conserves general function over specific form.
Melissa Duarte; David E Hill; G Adelmant; Michael A Calderwood; Hongyu Deng; Jarrod A Marto; Makoto Ohashi; Jennifer Roecklein-Canfield; Lili Wang; Eric Johannsen
An RS motif within the Epstein-Barr virus BLRF2 tegument protein is phosphorylated by SRPK2 and is important for viral replication.
Grégory Neveu; Chantal Rabourdin-Combe; Caroline Rolloy; Lionel Tafforeau; Frédéric Tangy; Gilles Travé; Marc Vidal; Pierre-Olivier Vidalain; Patricia Cassonnet; Caroline Demeret; Amélie Dricot; Michel Favre; David E Hill; Louis Jones; Vincent Lotteau; José Mendoza; Mandy Muller; Yves Jacob
Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.

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All Publications

2013: Xiaofeng Xin; Xinping Yang; Yingnan Zhang; Adenrele Akintobi; Charles Boone; Dryden Bouamalay; Aaron T Cheng; Jackie Cheng; Bridget Currell; David G Drubin; David Gfeller; Barth D Grant; Mark L Grimes; Ailan Guo; Tong Hao; David E Hill; Jingjing Li; Lianet Lopez; Adrien Lugari; Alevtina Pavlenco; Jean-François Rual; Kourosh Salehi-Ashtiani; Somasekar Seshagiri; Yun A Shen; Sachdev S Sidhu; Lin Sun; Raffi Tonikian; Marc Vidal; Gary D Bader
SH3 interactome conserves general function over specific form.
Molecular systems biology 2013;9():652.
2013: Melissa Duarte; David E Hill; G Adelmant; Michael A Calderwood; Hongyu Deng; Jarrod A Marto; Makoto Ohashi; Jennifer Roecklein-Canfield; Lili Wang; Eric Johannsen
An RS motif within the Epstein-Barr virus BLRF2 tegument protein is phosphorylated by SRPK2 and is important for viral replication.
PloS one 2013;8(1):e53512.
2012: Grégory Neveu; Chantal Rabourdin-Combe; Caroline Rolloy; Lionel Tafforeau; Frédéric Tangy; Gilles Travé; Marc Vidal; Pierre-Olivier Vidalain; Patricia Cassonnet; Caroline Demeret; Amélie Dricot; Michel Favre; David E Hill; Louis Jones; Vincent Lotteau; José Mendoza; Mandy Muller; Yves Jacob
Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.
Methods (San Diego, Calif.) 2012;58(4):349-59.
2012: Dominique Baas; Stéphanie Bertrand; Frederico Calhabeu; Sabine Caussanel-Boude; Emilie Chopin; Emilie Delaune; Alexandre Guiraud; David E Hill; Pierre Jurdic; Irma Machuca-Gayet; Fanny Pilot; Jean-François Rual; Laurent Schaeffer; Aurélia Vernay; Marc Vidal; Evelyne Goillot
CKIP-1 regulates mammalian and zebrafish myoblast fusion.
Journal of cell science 2012;125(Pt 16):3790-800.
2012: Debrah A Fine; Laurence Florens; Luxuan Guo; David E Hill; Robert L James; Anna Korkhin; Larisa Litovchick; Jarrod A Marto; Megha Padi; Orit Rozenblatt-Rosen; Soundarapandian Velmurgan; Marc Vidal; Michael P Washburn; Rosa Yoon; Ying Zhang; G Adelmant; Christian Berrios; Michael A Calderwood; Jingwei Cheng; Michael E Cusick; James A DeCaprio
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor.
PLoS pathogens 2012;8(10):e1002949.
2012: Nicolas Simonis; Jan Tavernier; Carine Van Lint; Didier Vertommen; Marc Vidal; Jean-François Willaert; Mathieu Boxus; Arsène Burny; Michael E Cusick; Sarah Daakour; Franck Dequiedt; Amélie Dricot; Jean-Stéphane Gatot; Tong Hao; David E Hill; Tomoko Hirozane-Kishikawa; Richard Kettmann; Niels Klitgord; Sébastien Legros; Irma Lemmens; Maud Martin; vincent navratil; Jean-François Rual; Jean-Claude Twizere
Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
Retrovirology 2012;9():26.
2011: John S Reece-Hoyes; Kourosh Salehi-Ashtiani; Xinping Yang; Heng Zhu; A Rasim Barutcu; Seth Blackshaw; Job Dekker; David E Hill; Jun Seop Jeong; Lizhi Jiang; Andrew MacWilliams; Rachel Patton McCord; Albertha J M Walhout
Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.
Nature methods 2011;8(12):1050-2.
2011: Kristina Schild-Prüfert; Sarit Smolikov; Marc Vidal; Yanjie Gu; David E Hill; Marina Hincapie; Kent McDonald; Takamune T Saito; Mónica P Colaiácovo
Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans.
Genetics 2011;189(2):411-21.
2011: Xiaoping Yang; Xinping Yang; Kourosh Salehi-Ashtiani; Yun Shen; Serena J Silver; Sapana R Thomas; Marc Vidal; Ozan Alkan; Dawit Balcha; Tashfeen Bhimdi; Jesse S Boehm; Changyu Fan; Lila Ghamsari; Thomas M Green; William C Hahn; Tong Hao; Haley Hieronymus; David E Hill; Cory M Johannessen; Chenwei Lin; Rakela Lubonja; Ryan R Murray; Cindy Nguyen; David E Root
A public genome-scale lentiviral expression library of human ORFs.
Nature methods 2011;8(8):659-61.
2011: M Shahid Mukhtar; Marc T Nishimura; Samuel J Pevzner; Matthew M Poulin; Viviana Romero; Frederick P Roth; Balaji Santhanam; Jens Steinbrenner; Stanley Tam; Murat Tasan; Jean Vandenhaute; Marc Vidal; Jim Beynon; Mike Boxem; Pascal Braun; Anne-Ruxandra Carvunis; Huaming Chen; Susan E Donovan; Matija Dreze; Joseph R Ecker; Petra Epple; Lantian Gai; Mary Galli; Fana Gebreab; Lila Ghamsari; Bryan J Gutierrez; Tong Hao; Christopher J Harbort; Yijian He; David E Hill; Nathan McDonald; Dario Monachello; Jonathan Moore; Jeffery L Dangl
Independently evolved virulence effectors converge onto hubs in a plant immune system network.
Science (New York, N.Y.) 2011;333(6042):596-601.
2011: Marie de Barsy; Didier Filopon; Jean-Pierre Gorvel; David E Hill; Alexandre Jamet; Géraldine Laloux; Jean-Jacques LETESSON; Alexandre Muller; Cécile Nicolas; Bernard Nkengfac; Jean-François Rual; Suzana P Salcedo; Jean-Claude Twizere; Jean Vandenhaute; Xavier De Bolle
Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2.
Cellular microbiology 2011;13(7):1044-58.
2011: Yasunari Sakai; Chad A Shaw; Zaina Al-Mohtaseb; Brian C Dawson; Diana V Dugas; David E Hill; Huda Y Zoghbi
Protein interactome reveals converging molecular pathways among autism disorders.
Science translational medicine 2011;3(86):86ra49.
2011: Haiyuan Yu; Leah Tardivo; Stanley Tam; Evan Weiner; Fana Gebreab; Changyu Fan; Nenad Svrzikapa; Tomoko Hirozane-Kishikawa; Edward Rietman; Xinping Yang; Julie Sahalie; Kourosh Salehi-Ashtiani; Tong Hao; Michael E Cusick; David E Hill; Frederick P Roth; Pascal Braun; Marc Vidal
Next-generation sequencing to generate interactome datasets.
Nature methods 2011;8(6):478-80.
2011: Zhihu Ding; Chang-Jiun Wu; Gerald Chu; Yonghong Xiao; Dennis Ho; Jingfang Zhang; Samuel R Perry; Emma S Labrot; Xiaoqiu Wu; Rosina Lis; Yujin Hoshida; David Hiller; Baoli Hu; Shan Jiang; Hongwu Zheng; Alexander H Stegh; Kenneth L Scott; Sabina Signoretti; Nabeel Bardeesy; Y Alan Wang; David E Hill; Todd R Golub; Meir J Stampfer; Wing H Wong; Massimo Loda; Lorelei Mucci; Lynda Chin; Ronald A DePinho
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
Nature 2011;470(7333):269-73.
2011: Juliette J Kahle; Natali Gulbahce; Chad A Shaw; Janghoo Lim; David E Hill; Albert-László Barabási; Huda Y Zoghbi
Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.
Human molecular genetics 2011;20(3):510-27.
2011: Benoit Charloteaux; Michael E Cusick; Matija Dreze; David E Hill; Quan Zhong; Marc Vidal
Protein-protein interactions and networks: forward and reverse edgetics.
Methods in molecular biology (Clifton, N.J.) 2011;759():197-213.
2010: Cory M Johannessen; Jesse S Boehm; So Young Kim; Sapana R Thomas; Leslie Wardwell; Laura A Johnson; Caroline M Emery; Nicolas Stransky; Alexandria P Cogdill; Jordi Barretina; Giordano Caponigro; Haley Hieronymus; Ryan R Murray; Kourosh Salehi-Ashtiani; David E Hill; Marc Vidal; Jean J Zhao; Xiaoping Yang; Ozan Alkan; Sungjoon Kim; Jennifer L Harris; Christopher J Wilson; Vic E Myer; Peter M Finan; David E Root; Thomas M Roberts; Todd Golub; Keith T Flaherty; Reinhard Dummer; Barbara L Weber; William R Sellers; Robert Schlegel; Jennifer A Wargo; William C Hahn; Levi A Garraway
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Nature 2010;468(7326):968-72.
2010: Fanny Pilot-Storck; Emilie Chopin; Jean-François Rual; Anais Baudot; Pavel Dobrokhotov; Marc Robinson-Rechavi; Christine Brun; Michael E Cusick; David E Hill; Laurent Schaeffer; Marc Vidal; Evelyne Goillot
Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.
Molecular & cellular proteomics : MCP 2010;9(7):1578-93.
2010: Matija Dreze; Dario Monachello; Claire Lurin; Michael E Cusick; David E Hill; Marc Vidal; Pascal Braun
High-quality binary interactome mapping.
Methods in enzymology 2010;470():281-315.
2010: Han Yan; Kavitha Venkatesan; John E Beaver; Niels Klitgord; Muhammed A Yildirim; Tong Hao; David E Hill; Michael E Cusick; Norbert Perrimon; Frederick P Roth; Marc Vidal
A genome-wide gene function prediction resource for Drosophila melanogaster.
PloS one 2010;5(8):e12139.
2009: Sagi D Shapira; Irit Gat-Viks; Bennett O V Shum; Amelie Dricot; Marciela M de Grace; Liguo Wu; Piyush B Gupta; Tong Hao; Serena J Silver; David E Root; David E Hill; Aviv Regev; Nir Hacohen
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.
Cell 2009;139(7):1255-67.
2009: Kourosh Salehi-Ashtiani; Chenwei Lin; Tong Hao; Yun Shen; David Szeto; Xinping Yang; Lila Ghamsari; HanJoo Lee; Changyu Fan; Ryan R Murray; Stuart Milstein; Nenad Svrzikapa; Michael E Cusick; Frederick P Roth; David E Hill; Marc Vidal
Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome.
Genome research 2009;19(12):2334-42.
2009: Matija Dreze; Benoit Charloteaux; Stuart Milstein; Pierre-Olivier Vidalain; Muhammed A Yildirim; Quan Zhong; Nenad Svrzikapa; Viviana Romero; Géraldine Laloux; Robert Brasseur; Jean Vandenhaute; Mike Boxem; Michael E Cusick; David E Hill; Marc Vidal
'Edgetic' perturbation of a C. elegans BCL2 ortholog.
Nature methods 2009;6(11):843-9.
2009: Ani Manichaikul; Lila Ghamsari; Erik F Y Hom; Chenwei Lin; Ryan R Murray; Roger L Chang; S Balaji; Tong Hao; Yun Shen; Arvind K Chavali; Ines Thiele; Xinping Yang; Changyu Fan; Elizabeth Mello; David E Hill; Marc Vidal; Kourosh Salehi-Ashtiani; Jason A Papin
Metabolic network analysis integrated with transcript verification for sequenced genomes.
Nature methods 2009;6(8):589-92.
2009: Xiaofeng Xin; Jean-François Rual; Tomoko Hirozane-Kishikawa; David E Hill; Marc Vidal; Charles Boone; Nicolas Thierry-Mieg
Shifted Transversal Design smart-pooling for high coverage interactome mapping.
Genome research 2009;19(7):1262-9.
2009: Quan Zhong; Nicolas Simonis; Qian-Ru Li; Benoit Charloteaux; Fabien Heuze; Niels Klitgord; Stanley Tam; Haiyuan Yu; Kavitha Venkatesan; Danny Mou; Venus Swearingen; Muhammed A Yildirim; Han Yan; Amélie Dricot; David Szeto; Chenwei Lin; Tong Hao; Changyu Fan; Stuart Milstein; Denis Dupuy; Robert Brasseur; David E Hill; Michael E Cusick; Marc Vidal
Edgetic perturbation models of human inherited disorders.
Molecular systems biology 2009;5():321.
2009: Nicolas Simonis; Jean-François Rual; Anne-Ruxandra Carvunis; Murat Tasan; Irma Lemmens; Tomoko Hirozane-Kishikawa; Tong Hao; Julie M Sahalie; Kavitha Venkatesan; Fana Gebreab; Sebiha Cevik; Niels Klitgord; Changyu Fan; Pascal Braun; Ning Li; Nono Ayivi-Guedehoussou; Elizabeth Dann; Nicolas Bertin; David Szeto; Amélie Dricot; Muhammed A Yildirim; Chenwei Lin; Anne-Sophie de Smet; Huey-Ling Kao; Christophe Simon; Alex Smolyar; Jin Sook Ahn; Muneesh Tewari; Mike Boxem; Stuart Milstein; Haiyuan Yu; Matija Dreze; Jean Vandenhaute; Kristin C Gunsalus; Michael E Cusick; David E Hill; Jan Tavernier; Frederick P Roth; Marc Vidal
Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network.
Nature methods 2009;6(1):47-54.
2009: Michael E Cusick; Haiyuan Yu; A Smolyar; Kavitha Venkatesan; Anne-Ruxandra Carvunis; Nicolas Simonis; Jean-François Rual; Heather Peek Borick; Pascal Braun; Matija Dreze; Jean Vandenhaute; Mary Galli; Junshi Yazaki; David E Hill; Joseph R Ecker; Frederick P Roth; Marc Vidal
Literature-curated protein interaction datasets.
Nature methods 2009;6(1):39-46.
2009: Kavitha Venkatesan; Jean-François Rual; Alexei Vazquez; Ulrich Stelzl; Irma Lemmens; Tomoko Hirozane-Kishikawa; Tong Hao; Martina Zenkner; Xiaofeng Xin; Kwang-Il Goh; Muhammed A Yildirim; Nicolas Simonis; Kathrin Heinzmann; Fana Gebreab; Julie M Sahalie; Sebiha Cevik; Christophe Simon; Anne-Sophie de Smet; Elizabeth Dann; Alex Smolyar; Arunachalam Vinayagam; Haiyuan Yu; David Szeto; Heather Peek Borick; Amélie Dricot; Niels Klitgord; Ryan R Murray; Chenwei Lin; Maciej Lalowski; Jan Timm; Kirstin Rau; Charles Boone; Pascal Braun; Michael E Cusick; Frederick P Roth; David E Hill; Jan Tavernier; Erich E Wanker; Albert-László Barabási; Marc Vidal
An empirical framework for binary interactome mapping.
Nature methods 2009;6(1):83-90.
2009: Pascal Braun; Murat Tasan; Matija Dreze; Miriam Barrios-Rodiles; Irma Lemmens; Haiyuan Yu; Julie M Sahalie; Ryan R Murray; Luba Roncari; Anne-Sophie de Smet; Kavitha Venkatesan; Jean-François Rual; Jean Vandenhaute; Michael E Cusick; Tony Pawson; David E Hill; Jan Tavernier; Jeffrey L Wrana; Frederick P Roth; Marc Vidal
An experimentally derived confidence score for binary protein-protein interactions.
Nature methods 2009;6(1):91-7.
2008: James L Hartley; Kourosh Salehi-Ashtiani; David E Hill
Proteome expression moves in vitro: resources and tools for harnessing the human proteome.
Nature methods 2008;5(12):1001-2.
2008: Haiyuan Yu; Pascal Braun; Muhammed A Yildirim; Irma Lemmens; Kavitha Venkatesan; Julie Sahalie; Tomoko Hirozane-Kishikawa; Fana Gebreab; Na Li; Nicolas Simonis; Tong Hao; Jean-François Rual; Amélie Dricot; Alexei Vazquez; Ryan R Murray; Christophe Simon; Leah Tardivo; Stanley Tam; Nenad Svrzikapa; Changyu Fan; Anne-Sophie de Smet; Adriana Motyl; Michael E Hudson; Juyong Park; Xiaofeng Xin; Michael E Cusick; Troy Moore; Charlie Boone; Michael Snyder; Frederick P Roth; Albert-László Barabási; Jan Tavernier; David E Hill; Marc Vidal
High-quality binary protein interaction map of the yeast interactome network.
Science (New York, N.Y.) 2008;322(5898):104-10.
2008: Mike Boxem; Zoltan Maliga; Niels Klitgord; Na Li; Irma Lemmens; Miyeko Mana; Lorenzo de Lichtervelde; Joram D Mul; Diederik van de Peut; Maxime Devos; Nicolas Simonis; Muhammed A Yildirim; Murat Cokol; Huey-Ling Kao; Anne-Sophie de Smet; Haidong Wang; Anne-Lore Schlaitz; Tong Hao; Stuart Milstein; Changyu Fan; Mike Tipsword; Kevin Drew; Matilde Galli; Kahn Rhrissorrakrai; David Drechsel; Daphne Koller; Frederick P Roth; Lilia M Iakoucheva; Keith Dunker; Richard Bonneau; Kristin C Gunsalus; David E Hill; Fabio Piano; Jan Tavernier; Sander van den Heuvel; Anthony A Hyman; Marc Vidal
A protein domain-based interactome network for C. elegans early embryogenesis.
Cell 2008;134(3):534-45.
2008: Siming Li; Chang Liu; Na Li; Tong Hao; Ting Han; David E Hill; Marc Vidal; Jiandie Lin
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism.
Cell metabolism 2008;8(2):105-17.
2008: Qian-Ru Li; Anne-Ruxandra Carvunis; Haiyuan Yu; Jing-Dong J Han; Quan Zhong; Nicolas Simonis; Stanley Tam; Tong Hao; Niels J Klitgord; Denis Dupuy; Danny Mou; Ilan Wapinski; Aviv Regev; David E Hill; Michael E Cusick; Marc Vidal
Revisiting the Saccharomyces cerevisiae predicted ORFeome.
Genome research 2008;18(8):1294-303.
2008: David J Pagliarini; Sarah E Calvo; Betty Chang; Sunil A Sheth; Scott B Vafai; Shao-En Ong; Geoffrey A Walford; Canny Sugiana; Avihu Boneh; William K Chen; David E Hill; Marc Vidal; James G Evans; David R Thorburn; Steven A Carr; Vamsi K Mootha
A mitochondrial protein compendium elucidates complex I disease biology.
Cell 2008;134(1):112-23.
2008: Kourosh Salehi-Ashtiani; Xinping Yang; Adnan Derti; Weidong Tian; Tong Hao; Chenwei Lin; Kathryn Makowski; Lei Shen; Ryan R Murray; David Szeto; Nadeem Tusneem; Douglas R Smith; Michael E Cusick; David E Hill; Frederick P Roth; Marc Vidal
Isoform discovery by targeted cloning, 'deep-well' pooling and parallel sequencing.
Nature methods 2008;5(7):597-600.
2008: Janghoo Lim; crespo-barreto juan; Paymaan Jafar-Nejad; Aaron B Bowman; Ronald Richman; David E Hill; Harry T Orr; Huda Y Zoghbi
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
Nature 2008;452(7188):713-8.
2007: Miguel Angel Pujana; Jing-Dong J Han; Lea M Starita; Kristen N Stevens; Muneesh Tewari; Jin Sook Ahn; Gad Rennert; Víctor Moreno; Tomas Kirchhoff; Bert Gold; Volker Assmann; Wael ElShamy; Jean-François Rual; Douglas A Levine; Laura S Rozek; Rebecca Gelman; Kristin C Gunsalus; Roger A. Greenberg; Bijan Sobhian; Nicolas Bertin; Kavitha Venkatesan; Nono Ayivi-Guedehoussou; Xavier Sole; Pilar Hernández; Conxi Lázaro; Katherine L Nathanson; Barbara L Weber; Michael E Cusick; David E Hill; Kenneth Offit; David M Livingston; Stephen B Gruber; Jeffrey D Parvin; Marc Vidal
Network modeling links breast cancer susceptibility and centrosome dysfunction.
Nature genetics 2007;39(11):1338-49.
2007: Jesse S Boehm; Jean J Zhao; Jun Yao; So Young Kim; Ron Firestein; Ian F Dunn; Sarah K Sjostrom; Levi A Garraway; Stanislawa Weremowicz; Andrea L Richardson; Heidi Greulich; Carly J Stewart; Laura A Mulvey; Rhine R Shen; Lauren Ambrogio; Tomoko Hirozane-Kishikawa; David E Hill; Marc Vidal; Matthew Meyerson; Jennifer K Grenier; Greg Hinkle; David E Root; Thomas M Roberts; Eric S Lander; Kornelia Polyak; William C Hahn
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Cell 2007;129(6):1065-79.
2007: Michael A Calderwood; Kavitha Venkatesan; Li Xing; Michael R Chase; Alexei Vazquez; Amy M Holthaus; Alexandra E Ewence; Ning Li; Tomoko Hirozane-Kishikawa; David E Hill; Marc Vidal; Elliott Kieff; Eric Johannsen
Epstein-Barr virus and virus human protein interaction maps.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7606-11.
2007: Philippe Lamesch; Ning Li; Stuart Milstein; Changyu Fan; Tong Hao; Gabor Szabo; Zhenjun Hu; Kavitha Venkatesan; Graeme Bethel; Paul Martin; Jane Rogers; Stephanie Lawlor; Stuart McLaren; Amélie Dricot; Heather Peek Borick; Michael E Cusick; Jean Vandenhaute; Ian Dunham; David E Hill; Marc Vidal
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Genomics 2007;89(3):307-15.
2006: Janghoo Lim; Tong Hao; Chad Shaw; Akash J Patel; Gábor Szabó; Jean-François Rual; C Joseph Fisk; Ning Li; Alex Smolyar; David E Hill; Albert-László Barabási; Marc Vidal; Huda Y Zoghbi
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell 2006;125(4):801-14.
2006: Gary Temple; Philippe Lamesch; Stuart Milstein; David E Hill; Lukas Wagner; Troy Moore; Marc Vidal
From genome to proteome: developing expression clone resources for the human genome.
Human molecular genetics 2006;15 Spec No 1():R31-43.
2006: Fabio Piano; Kristin C Gunsalus; David E Hill; Marc Vidal
C. elegans network biology: a beginning.
WormBook : the online review of C. elegans biology 2006;():1-20.
2005: William K Gillette; Dominic Esposito; Peter H Frank; Ming Zhou; Li-Rong Yu; Catherine Jozwik; Xiuying Zhang; Brighid McGowan; David M Jacobowitz; Harvey B Pollard; Tong Hao; David E Hill; Marc Vidal; Thomas P Conrads; Timothy D Veenstra; James L Hartley
Pooled ORF expression technology (POET): using proteomics to screen pools of open reading frames for protein expression.
Molecular & cellular proteomics : MCP 2005;4(11):1647-52.
2005: Jean-François Rual; Kavitha Venkatesan; Tong Hao; Tomoko Hirozane-Kishikawa; Amélie Dricot; Ning Li; Gabriel F Berriz; Frank Gibbons; Matija Dreze; Nono Ayivi-Guedehoussou; Niels Klitgord; Christophe Simon; Mike Boxem; Stuart Milstein; Jennifer Rosenberg; Debra S Goldberg; Lan V Zhang; Sharyl L Wong; Giovanni Franklin; Siming Li; Joanna S Albala; Janghoo Lim; Carlene Fraughton; Estelle Llamosas; Sebiha Cevik; Camille Bex; Philippe Lamesch; Robert S Sikorski; Jean Vandenhaute; Huda Y Zoghbi; Alex Smolyar; Stephanie Bosak; Reynaldo Sequerra; Lynn Doucette-Stamm; Michael E Cusick; David E Hill; Frederick P Roth; Marc Vidal
Towards a proteome-scale map of the human protein-protein interaction network.
Nature 2005;437(7062):1173-8.
2005: Michael E Cusick; Niels Klitgord; Marc Vidal; David E Hill
Interactome: gateway into systems biology.
Human molecular genetics 2005;14 Spec No. 2():R171-81.
2005: Derek Sieburth; QueeLim Ch'ng; Michael Dybbs; Masoud Tavazoie; Scott Kennedy; Duo Wang; Denis Dupuy; Jean-François Rual; David E Hill; Marc Vidal; Gary Ruvkun; Joshua M Kaplan
Systematic analysis of genes required for synapse structure and function.
Nature 2005;436(7050):510-7.
2005: Marie-Elaine Caruso; Sarah Jenna; Simon Beaulne; Eun-Hye Lee; Anne Bergeron; Cédric Chauve; Philippe Roby; Jean-François Rual; David E Hill; Marc Vidal; Roger Bossé; Eric Chevet
Biochemical clustering of monomeric GTPases of the Ras superfamily.
Molecular & cellular proteomics : MCP 2005;4(7):936-44.
2005: Anita G Fernandez; Kristin C Gunsalus; Jerry Huang; Ling-Shiang Chuang; Nancy Ying; Hsiao-Lan Liang; Caroline Tang; Aaron J Schetter; Charles Zegar; Jean-François Rual; David E Hill; Valerie Reinke; Marc Vidal; Fabio Piano
New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones.
Genome research 2005;15(2):250-9.
2004: Amélie Dricot; Jean-François Rual; Philippe Lamesch; Nicolas Bertin; Denis Dupuy; Tong Hao; Christophe Lambert; Regis Hallez; Jean-Marc Delroisse; Jean Vandenhaute; Ignacio Lopez-Goñi; Ignacio Moriyon; Juan M Garcia-Lobo; Félix J Sangari; Alastair P Macmillan; Sally J Cutler; Adrian M Whatmore; Stephanie Bozak; Reynaldo Sequerra; Lynn Doucette-Stamm; Marc Vidal; David E Hill; Jean-Jacques LETESSON; Xavier De Bolle
Generation of the Brucella melitensis ORFeome version 1.1.
Genome research 2004;14(10B):2201-6.
2004: Denis Dupuy; Qian-Ru Li; Bart Deplancke; Mike Boxem; Tong Hao; Philippe Lamesch; Reynaldo Sequerra; Stephanie Bosak; Lynn Doucette-Stamm; Ian A Hope; David E Hill; Albertha J M Walhout; Marc Vidal
A first version of the Caenorhabditis elegans Promoterome.
Genome research 2004;14(10B):2169-75.
2004: Jean-François Rual; Julian Ceron; John Koreth; Tong Hao; Anne-Sophie Nicot; Tomoko Hirozane-Kishikawa; Jean Vandenhaute; Stuart H Orkin; David E Hill; Sander van den Heuvel; Marc Vidal
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library.
Genome research 2004;14(10B):2162-8.
2004: Jean-François Rual; Tomoko Hirozane-Kishikawa; Tong Hao; Nicolas Bertin; Siming Li; Amélie Dricot; Ning Li; Jennifer Rosenberg; Philippe Lamesch; Pierre-Olivier Vidalain; Tracey R Clingingsmith; James L Hartley; Dominic Esposito; David L Cheo; Troy Moore; Blake Simmons; Reynaldo Sequerra; Stephanie Bosak; Lynn Doucette-Stamm; Christian Le Peuch; Jean Vandenhaute; Michael E Cusick; Joanna S Albala; David E Hill; Marc Vidal
Human ORFeome version 1.1: a platform for reverse proteomics.
Genome research 2004;14(10B):2128-35.
2004: Chi-Hao Luan; Shihong Qiu; James B Finley; Mike Carson; Rita J Gray; Wenying Huang; David Johnson; Jun Tsao; Jérôme Reboul; Philippe Vaglio; David E Hill; Marc Vidal; Lawrence J Delucas; Ming Luo
High-throughput expression of C. elegans proteins.
Genome research 2004;14(10B):2102-10.
2004: Philippe Lamesch; Stuart Milstein; Tong Hao; Jennifer Rosenberg; Ning Li; Reynaldo Sequerra; Stephanie Bosak; Lynn Doucette-Stamm; Jean Vandenhaute; David E Hill; Marc Vidal
C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions.
Genome research 2004;14(10B):2064-9.
2004: David E Hill; Michael A Brasch; Anthony A del Campo; Lynn Doucette-Stamm; James I Garrels; Judith Glaven; James L Hartley; James R Hudson; Troy Moore; Marc Vidal
Academia-industry collaboration: an integral element for building "omic" resources.
Genome research 2004;14(10B):2010-4.
2004: Jean-François Rual; David E Hill; Marc Vidal
ORFeome projects: gateway between genomics and omics.
Current opinion in chemical biology 2004;8(1):20-5.
2004: Siming Li; Christopher M Armstrong; Nicolas Bertin; Hui Ge; Stuart Milstein; Mike Boxem; Pierre-Olivier Vidalain; Jing-Dong J Han; Alban Chesneau; Tong Hao; Debra S Goldberg; Ning Li; Monica Martinez; Jean-François Rual; Philippe Lamesch; Lai Xu; Muneesh Tewari; Sharyl L Wong; Lan V Zhang; Gabriel F Berriz; Laurent Jacotot; Philippe Vaglio; Jérôme Reboul; Tomoko Hirozane-Kishikawa; Qianru Li; Harrison W Gabel; Ahmed Elewa; Bridget Baumgartner; Debra J Rose; Haiyuan Yu; Stephanie Bosak; Reynaldo Sequerra; Andrew Fraser; Susan E Mango; William M Saxton; Susan Strome; Sander Van Den Heuvel; Fabio Piano; Jean Vandenhaute; Claude Sardet; Mark Gerstein; Lynn Doucette-Stamm; Kristin C Gunsalus; J Wade Harper; Michael E Cusick; Frederick P Roth; David E Hill; Marc Vidal
A map of the interactome network of the metazoan C. elegans.
Science (New York, N.Y.) 2004;303(5657):540-3.
2004: Simon J Boulton; Julie S Martin; Jolanta Polanowska; David E Hill; Anton Gartner; Marc Vidal
BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans.
Current biology : CB 2004;14(1):33-9.
2003: Jérôme Reboul; Philippe Vaglio; Jean-François Rual; Philippe Lamesch; Monica Martinez; Christopher M Armstrong; Siming Li; Laurent Jacotot; Nicolas Bertin; Rekin's Janky; Troy Moore; James R Hudson; James L Hartley; Michael A Brasch; Jean Vandenhaute; Simon J Boulton; Gregory A Endress; Sarah Jenna; Eric Chevet; Vasilis Papasotiropoulos; Peter P Tolias; Jason Ptacek; Mike Snyder; Raymond Huang; Mark R Chance; Hongmei Lee; Lynn Doucette-Stamm; David E Hill; Marc Vidal
C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression.
Nature genetics 2003;34(1):35-41.
2002: Simon J Boulton; Anton Gartner; Jérôme Reboul; Philippe Vaglio; Nicholas J Dyson; David E Hill; Marc Vidal
Combined functional genomic maps of the C. elegans DNA damage response.
Science (New York, N.Y.) 2002;295(5552):127-31.
2001: Shuji Kishi; Xiao Zhen Zhou; Y Ziv; C Khoo; David E Hill; Y Shiloh; Kun Ping Lu
Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.
The Journal of biological chemistry 2001;276(31):29282-91.
2001: David E Hill
Mutagenesis with degenerate oligonucleotides: creating numerous mutations in a small DNA sequence.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 8():Unit8.2A.
2001: Jérôme Reboul; Philippe Vaglio; N Tzellas; N Thierry-Mieg; Troy Moore; C Jackson; T Shin-i; Y Kohara; Danielle Thierry-Mieg; Jean Thierry-Mieg; Hongmei Lee; J Hitti; Lynn Doucette-Stamm; James L Hartley; Gary F Temple; Michael A Brasch; Jean Vandenhaute; Philippe Lamesch; David E Hill; Marc Vidal
Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. elegans.
Nature genetics 2001;27(3):332-6.
2000: PM Flatt; Kornelia Polyak; Luo Jia Tang; CD Scatena; Matthew D Westfall; L A Rubinstein; J Yu; Kenneth W Kinzler; Bert Vogelstein; David E Hill; Jennifer A Pietenpol
p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest.
Cancer letters 2000;156(1):63-72.
2000: Lois A Annab; Natalay Kouprina; Greg Solomon; P LouAnn Cable; David E Hill; J Carl Barrett; Vladimir Larionov; Cynthia A Afshari
Isolation of a functional copy of the human BRCA1 gene by transformation-associated recombination in yeast.
Gene 2000;250(1-2):201-8.
2000: Kenji Hibi; Barry Trink; Meera Patturajan; William H Westra; Otavia L Caballero; David E Hill; Edward Ratovitski; Jin Jen; David Sidransky
AIS is an oncogene amplified in squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5462-7.
1998: Jann N. Sarkaria; Randal S Tibbetts; EC Busby; A P Kennedy; David E Hill; Robert T Abraham
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.
Cancer research 1998;58(19):4375-82.
1998: L Berrueta; Stine-Kathrein Kraeft; Jennifer Tirnauer; Scott C Schuyler; Lan Bo Chen; David E Hill; David Pellman; Barbara E Bierer
The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10596-601.
1997: L Shick; J H Carman; John K Choi; K Somasundaram; M Burrell; David E Hill; YX Zeng; Yihan Wang; K G Wiman; KE Salhany; Tom Kadesch; John G Monroe; L A Donehower; Wafik S El-Deiry
Decreased immunoglobulin deposition in tumors and increased immature B cells in p53-null mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(2):121-31.
1996: F Liu; David E Hill; Jonathan Chernoff
Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas).
The Journal of biological chemistry 1996;271(49):31290-5.
1996: R V Bhat; K J Axt; J S Fosnaugh; K J Smith; K A Johnson; David E Hill; Kenneth W Kinzler; Jay M Baraban
Expression of the APC tumor suppressor protein in oligodendroglia.
Glia 1996;17(2):169-74.
1995: L K Su; M Burrell; David E Hill; J Gyuris; R Brent; R Wiltshire; Jeffrey M. Trent; Bert Vogelstein; Kenneth W Kinzler
APC binds to the novel protein EB1.
Cancer research 1995;55(14):2972-7.
1995: Wafik S El-Deiry; T Tokino; Todd Waldman; J D Oliner; Victor E Velculescu; M Burrell; David E Hill; E Healy; J L Rees; Stanley R Hamilton
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.
Cancer research 1995;55(13):2910-9.
1994: J Kusari; K A Kenner; K I Suh; David E Hill; Robert R Henry
Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance.
The Journal of clinical investigation 1994;93(3):1156-62.
1994: Wafik S El-Deiry; J W Harper; Patrick M O'Connor; Victor E Velculescu; Shilpy Sharma; J Jackman; J A Pietenpol; M Burrell; David E Hill; Y Wang
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.
Cancer research 1994;54(5):1169-74.
1993: K A Kenner; David E Hill; Jerrold M Olefsky; J Kusari
Regulation of protein tyrosine phosphatases by insulin and insulin-like growth factor I.
The Journal of biological chemistry 1993;268(34):25455-62.
1993: L K Su; K A Johnson; K J Smith; David E Hill; Bert Vogelstein; Kenneth W Kinzler
Association between wild type and mutant APC gene products.
Cancer research 1993;53(12):2728-31.
1993: Shyamala Maheswaran; S Park; A Bernard; J F Morris; F J Rauscher; David E Hill; Daniel A Haber
Physical and functional interaction between WT1 and p53 proteins.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5100-4.
1993: C V Johnson; D E Cool; moira glaccum; N Green; Edmond H Fischer; A Bruskin; David E Hill; Jeanne B Lawrence
Isolation and mapping of human T-cell protein tyrosine phosphatase sequences: localization of genes and pseudogenes discriminated using fluorescence hybridization with genomic versus cDNA probes.
Genomics 1993;16(3):619-29.
1993: F S Leach; T Tokino; P Meltzer; M Burrell; J D Oliner; S Smith; David E Hill; David Sidransky; Kenneth W Kinzler; Bert Vogelstein
p53 Mutation and MDM2 amplification in human soft tissue sarcomas.
Cancer research 1993;53(10 Suppl):2231-4.
1993: A J Flint; M F Gebbink; B R Franza; David E Hill; N K Tonks
Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation.
The EMBO journal 1993;12(5):1937-46.
1993: A R Schievella; L A Paige; K A Johnson; David E Hill; Raymond L. Erikson
Protein tyrosine phosphatase 1B undergoes mitosis-specific phosphorylation on serine.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(4):239-46.
1993: K J Smith; K A Johnson; T M Bryan; David E Hill; Sanford Markowitz; James Willson; C Paraskeva; Gloria M Petersen; Stanley R Hamilton; Bert Vogelstein
The APC gene product in normal and tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2846-50.
1992: S Brown-Shimer; K A Johnson; David E Hill; A M Bruskin
Effect of protein tyrosine phosphatase 1B expression on transformation by the human neu oncogene.
Cancer research 1992;52(2):478-82.
1992: Nicholas K Tonks; Q Yang; A J Flint; M F Gebbink; B R Franza; David E Hill; H Sun; Susann M Brady-Kalnay
Protein tyrosine phosphatases: the problems of a growing family.
Cold Spring Harbor symposia on quantitative biology 1992;57():87-94.
1990: S Brown-Shimer; K A Johnson; Jeanne B Lawrence; C Johnson; A Bruskin; N R Green; David E Hill
Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5148-52.
1990: David E Hill; R Aldape; J D Rozzell
Nucleotide sequence of a cyclodextrin glucosyltransferase gene, cgtA, from Bacillus licheniformis.
Nucleic acids research 1990;18(1):199.
1989: David E Hill
Integrative transformation of yeast using electroporation.
Nucleic acids research 1989;17(19):8011.
1988: David E Hill; Kevin Struhl
Molecular characterization of GCD1, a yeast gene required for general control of amino acid biosynthesis and cell-cycle initiation.
Nucleic acids research 1988;16(19):9253-65.
1988: David E Hill; R Boulay; D Rogers
Complete nucleotide sequence of the peroxisomal acyl CoA oxidase from the alkane-utilizing yeast Candida maltosa.
Nucleic acids research 1988;16(1):365-6.
1987: David E Hill; A R Oliphant; K Struhl
Mutagenesis with degenerate oligonucleotides: an efficient method for saturating a defined DNA region with base pair substitutions.
Methods in enzymology 1987;155():558-68.
1987: K Struhl; David E Hill
Two related regulatory sequences are required for maximal induction of Saccharomyces cerevisiae his3 transcription.
Molecular and cellular biology 1987;7(1):104-10.
1986: David E Hill; K Struhl
A rapid method for determining tRNA charging levels in vivo: analysis of yeast mutants defective in the general control of amino acid biosynthesis.
Nucleic acids research 1986;14(24):10045-51.
1986: David E Hill; I A Hope; J P Macke; K Struhl
Saturation mutagenesis of the yeast his3 regulatory site: requirements for transcriptional induction and for binding by GCN4 activator protein.
Science (New York, N.Y.) 1986;234(4775):451-7.
1985: K Struhl; W Chen; David E Hill; I A Hope; M A Oettinger
Constitutive and coordinately regulated transcription of yeast genes: promoter elements, positive and negative regulatory sites, and DNA binding proteins.
Cold Spring Harbor symposia on quantitative biology 1985;50():489-503.