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Stephen Wilton Edwards

Research Profile

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Oligonucleotide Array Sequence Analysis

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Chemicals & Drugs

Water Pollutants, Chemical

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Publications

TOP 3
Ila Cote; David J Dix; Stephen Wilton Edwards; Paul T Anastas; Linda S Birnbaum; Rebecca M Clark; Peter W Preuss
Advancing the next generation of health risk assessment.
Daniel L Villeneuve; Karen H Watanabe; Lyle D Burgoon; Nancy D Denslow; Stephen Wilton Edwards; Natàlia Garcia-Reyero; Carlie A Lalone; Zhenhong Li; Dalma Martinović-Weigelt; Edward F Orlando; Edward J Perkins; Gerald T Ankley
A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis.
Jane Gallagher; Brooke Heidenfelder; Gina Andrews; Stephen Wilton Edwards; Edward Hudgens; J Inmon; Markey Johnson; Lucas Matthew Neas; Haluk Ozkaynak; David Reif; Scott Rhoney; Ann Williams; Ronald Williams; Elaine Cohen Hubal
Mechanistic indicators of childhood asthma (MICA) study: piloting an integrative design for evaluating environmental health.

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All Publications

2012: Ila Cote; David J Dix; Stephen Wilton Edwards; Paul T Anastas; Linda S Birnbaum; Rebecca M Clark; Peter W Preuss
Advancing the next generation of health risk assessment.
Environmental health perspectives 2012;120(11):1499-502.
2012: Daniel L Villeneuve; Karen H Watanabe; Lyle D Burgoon; Nancy D Denslow; Stephen Wilton Edwards; Natàlia Garcia-Reyero; Carlie A Lalone; Zhenhong Li; Dalma Martinović-Weigelt; Edward F Orlando; Edward J Perkins; Gerald T Ankley
A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis.
Mutation research 2012;746(2):151-62.
2011: Jane Gallagher; Brooke Heidenfelder; Gina Andrews; Stephen Wilton Edwards; Edward Hudgens; J Inmon; Markey Johnson; Lucas Matthew Neas; Haluk Ozkaynak; David Reif; Scott Rhoney; Ann Williams; Ronald Williams; Elaine Cohen Hubal
Mechanistic indicators of childhood asthma (MICA) study: piloting an integrative design for evaluating environmental health.
BMC public health 2011;11():344.
2011: Bonnie R Joubert; David M Reif; Stephen Wilton Edwards; Kevin A Leiner; Edward E Hudgens; Peter Egeghy; Jane E Gallagher; Elaine Cohen Hubal
Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.
BMC medical genetics 2011;12():25.
2011: Edward J Perkins; J Kevin Chipman; Stephen Wilton Edwards; Tanwir Habib; Francesco Falciani; Ronald Taylor; Graham Van Aggelen; Chris Vulpe; Philipp Antczak; Alexandre Loguinov
Reverse engineering adverse outcome pathways.
Environmental toxicology and chemistry / SETAC 2011;30(1):22-38.
2010: Rong-Lin Wang; David Bencic; Daniel L Villeneuve; Gerald T Ankley; james lazorchak; Stephen Wilton Edwards
A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species.
Aquatic toxicology (Amsterdam, Netherlands) 2010;98(3):230-44.
2010: Elaine A Cohen Hubal; Ann M Richard; Imran Shah; Jane Gallagher; Robert Kavlock; Jerry Blancato; Stephen Wilton Edwards
Exposure science and the U.S. EPA National Center for Computational Toxicology.
Journal of exposure science & environmental epidemiology 2010;20(3):231-6.
2010: Elaine A Cohen Hubal; Ann Richard; Lesa Aylward; Stephen Wilton Edwards; Jane Gallagher; Michael-Rock Goldsmith; Sastry Isukapalli; Rogelio Tornero-Velez; Eric Weber; Robert Kavlock
Advancing exposure characterization for chemical evaluation and risk assessment.
Journal of toxicology and environmental health. Part B, Critical reviews 2010;13(2-4):299-313.
2009: Zhidong Tu; Carmen Argmann; Kenny K Wong; Lyndon J Mitnaul; Stephen Wilton Edwards; Iliana C Sach; Jun Zhu; Eric E Schadt
Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network.
Genome research 2009;19(6):1057-67.
2009: Gerald T Ankley; David C Bencic; Michael S Breen; Timothy W Collette; Rory B Conolly; Nancy D Denslow; Stephen Wilton Edwards; Drew R Ekman; Natalia Garcia-Reyero; Kathleen M Jensen; James M Lazorchak; Dalma Martinović; David H Miller; Edward J Perkins; Edward F Orlando; Daniel L Villeneuve; Rong-Lin Wang; Karen Watanabe
Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.
Aquatic toxicology (Amsterdam, Netherlands) 2009;92(3):168-78.
2009: Brooke L Heidenfelder; David M Reif; Jack R Harkema; Elaine A Cohen Hubal; Edward E Hudgens; Lori A Bramble; James G Wagner; Masako Morishita; Gerald J Keeler; Stephen Wilton Edwards; Jane E Gallagher
Comparative microarray analysis and pulmonary changes in Brown Norway rats exposed to ovalbumin and concentrated air particulates.
Toxicological sciences : an official journal of the Society of Toxicology 2009;108(1):207-21.
2008: Stephen Wilton Edwards; R Julian Preston
Systems biology and mode of action based risk assessment.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(2):312-8.
2008: Mark P Keller; YounJeong Choi; Ping Wang; Dawn Belt Davis; Mary E Rabaglia; Angie T Oler; Donald S Stapleton; Carmen Argmann; Kathy L Schueler; Stephen Wilton Edwards; H Adam Steinberg; Elias Chaibub Neto; Robert Kleinhanz; Scott Turner; Marc K Hellerstein; Eric E Schadt; Brian S Yandell; Christina Kendziorski; Alan D Attie
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.
Genome research 2008;18(5):706-16.
2008: Yanqing Chen; Jun Zhu; Pek Yee Lum; Xia Yang; Shirly Pinto; Douglas J MacNeil; Chunsheng Zhang; john lamb; Stephen Wilton Edwards; Solveig K Sieberts; Amy Leonardson; Lawrence W Castellini; Susanna Wang; Marie-France Champy; Bin Zhang; Valur Emilsson; Sudheer Doss; Anatole Ghazalpour; Steve Horvath; Thomas A Drake; Aldons J Lusis; Eric E Schadt
Variations in DNA elucidate molecular networks that cause disease.
Nature 2008;452(7186):429-35.
2008: Wan-Lin Su; Barmak Modrek; Debraj GuhaThakurta; Stephen Wilton Edwards; Jyoti K Shah; Amit V Kulkarni; Archie Russell; Eric E Schadt; Jason M Johnson; John C Castle
Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences.
BMC genomics 2008;9():273.
2007: Jennifer Fostel; Lyle Burgoon; Craig Zwickl; Peter Lord; J Christopher Corton; Pierre R Bushel; Michael Cunningham; Liju Fan; Stephen Wilton Edwards; Susan Hester; James Stevens; Weida Tong; Michael Waters; Chihae Yang; Raymond W Tennant
Toward a checklist for exchange and interpretation of data from a toxicology study.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(1):26-34.
2006: Debraj GuhaThakurta; Tao Xie; Manish Anand; Stephen Wilton Edwards; Guoya Li; Susanna S Wang; Eric E Schadt
Cis-regulatory variations: a study of SNPs around genes showing cis-linkage in segregating mouse populations.
BMC genomics 2006;7():235.
2005: Margarete Mehrabian; Hooman Allayee; Jirina Stockton; Pek Yee Lum; Thomas A Drake; Lawrence W Castellani; Michael Suh; Christopher Armour; Stephen Wilton Edwards; john lamb; Aldons J Lusis; Eric E Schadt
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.
Nature genetics 2005;37(11):1224-33.
2005: Alessandra C L Cervino; Guoya Li; Stephen Wilton Edwards; Jun Zhu; Cathy Laurie; George Tokiwa; Pek Yee Lum; Susanna Wang; Lawrence W Castellani; Lawrence W Castellini; Aldons J Lusis; Sonia Carlson; Alan Sachs; Eric E Schadt
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.
Genomics 2005;86(5):505-17.
2005: Eric E Schadt; john lamb; Xia Yang; Jun Zhu; Stephen Wilton Edwards; Debraj GuhaThakurta; Solveig K Sieberts; Stephanie Monks; Marc Reitman; Chunsheng Zhang; Pek Yee Lum; Amy Leonardson; Rolf Thieringer; Joseph M Metzger; Liming Yang; John Castle; Haoyuan Zhu; Shera F Kash; Thomas A Drake; Alan Sachs; Aldons J Lusis
An integrative genomics approach to infer causal associations between gene expression and disease.
Nature genetics 2005;37(7):710-7.
2005: Jason Johnson; Stephen Wilton Edwards; Daniel D Shoemaker; Eric E Schadt
Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments.
Trends in genetics : TIG 2005;21(2):93-102.
2004: Stephanie A Monks; Amy Leonardson; H Zhu; P Cundiff; P Pietrusiak; Stephen Wilton Edwards; J W Phillips; A Sachs; E E Schadt
Genetic inheritance of gene expression in human cell lines.
American journal of human genetics 2004;75(6):1094-105.
2004: Eric E Schadt; Stephen Wilton Edwards; Debraj GuhaThakurta; Daniel J Holder; Lisa Ying; Vladimir Svetnik; Amy Leonardson; Kyle W Hart; Archie Russell; Guoya Li; Guy Cavet; John Castle; Paul McDonagh; Zhengyan Kan; Ronghua Chen; Andrew Kasarskis; Mihai Margarint; Ramon M Caceres; Jason Johnson; Christopher D Armour; Philip Garrett-Engele; Nicholas F Tsinoremas; Daniel D Shoemaker
A comprehensive transcript index of the human genome generated using microarrays and computational approaches.
Genome biology 2004;5(10):R73.
2004: Jun Zhu; Pek Yee Lum; john lamb; Debraj GuhaThakurta; Stephen Wilton Edwards; Rolf Thieringer; Joel P Berger; M S Wu; J Thompson; Alan Sachs; Eric E Schadt
An integrative genomics approach to the reconstruction of gene networks in segregating populations.
Cytogenetic and genome research 2004;105(2-4):363-74.
2003: Yudong D He; Hongyue Dai; Eric E Schadt; Guy Cavet; Stephen Wilton Edwards; Sergey B Stepaniants; Sven Duenwald; Robert Kleinhanz; Allan R Jones; Daniel D Shoemaker; Roland B Stoughton
Microarray standard data set and figures of merit for comparing data processing methods and experiment designs.
Bioinformatics (Oxford, England) 2003;19(8):956-65.
2001: D D Shoemaker; E E Schadt; C D Armour; Y D He; P Garrett-Engele; P D McDonagh; P M Loerch; A Leonardson; P Y Lum; Guy Cavet; L F Wu; S J Altschuler; Stephen Wilton Edwards; J King; J S Tsang; G Schimmack; J M Schelter; J Koch; Ziman Michael; M J Marton; B Li; P Cundiff; T Ward; J Castle; M Krolewski; M R Meyer; M Mao; J Burchard; M J Kidd; H Dai; J W Phillips; Peter Linsley; R Stoughton; S Scherer; M S Boguski
Experimental annotation of the human genome using microarray technology.
Nature 2001;409(6822):922-7.
2000: Stephen Wilton Edwards; Christopher M Tan; Lee E Limbird
Localization of G-protein-coupled receptors in health and disease.
Trends in pharmacological sciences 2000;21(8):304-8.
2000: Hagit Shatkay; Stephen Wilton Edwards; W John Wilbur; Mark S Boguski
Genes, themes and microarrays: using information retrieval for large-scale gene analysis.
Proceedings / ... International Conference on Intelligent Systems for Molecular Biology ; ISMB. International Conference on Intelligent Systems for Molecular Biology 2000;8():317-28.
1999: Stephen Wilton Edwards; Lee E Limbird
Role for the third intracellular loop in cell surface stabilization of the alpha2A-adrenergic receptor.
The Journal of biological chemistry 1999;274(23):16331-6.
1999: L Prezeau; Jeremy G Richman; Stephen Wilton Edwards; Lee E Limbird
The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha2-adrenergic receptor subtypes.
The Journal of biological chemistry 1999;274(19):13462-9.
1991: B M Peek; G T Ross; Stephen Wilton Edwards; G J Meyer; T J Meyer; Bruce W Erickson
Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris(2,2'-bipyridine)ruthenium(II).
International journal of peptide and protein research 1991;38(2):114-23.