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Saverio Cellamare

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TOP 3
leonardo pisani; Ramon Soto-Otero; Angela Stefanachi; Cosimo Altomare; Maria Barletta; Marco Catto; Saverio Cellamare; Antonellina Introcaso; Estefania Mendez-Alvarez; Orazio Nicolotti; Angelo Carotti
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.
Marco Catto; Saverio Cellamare; Francesco Leonetti; Orazio Nicolotti; Paolo Pesce; leonardo pisani; Angela Stefanachi; Angelo Carotti
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
Orazio Nicolotti; leonardo pisani; Angela Stefanachi; Paolo Tortorella; Marco Catto; Saverio Cellamare; Ilenia Giangreco; Francesco Leonetti; Fulvio Loiodice; Maria Barletta; Angelo Carotti
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9.

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All Publications

2013: leonardo pisani; Ramon Soto-Otero; Angela Stefanachi; Cosimo Altomare; Maria Barletta; Marco Catto; Saverio Cellamare; Antonellina Introcaso; Estefania Mendez-Alvarez; Orazio Nicolotti; Angelo Carotti
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.
Journal of medicinal chemistry 2013;56(6):2651-64.
2013: Marco Catto; Saverio Cellamare; Francesco Leonetti; Orazio Nicolotti; Paolo Pesce; leonardo pisani; Angela Stefanachi; Angelo Carotti
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
Bioorganic & medicinal chemistry 2013;21(1):146-52.
2012: Orazio Nicolotti; leonardo pisani; Angela Stefanachi; Paolo Tortorella; Marco Catto; Saverio Cellamare; Ilenia Giangreco; Francesco Leonetti; Fulvio Loiodice; Maria Barletta; Angelo Carotti
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9.
European journal of medicinal chemistry 2012;58():368-76.
2012: Diana A Stolfa; Lucia Altucci; Saverio Cellamare; Julia M Gajer; Manfred Jung; Angela Nebbioso; Angela Stefanachi; Angelo Carotti
Design, synthesis, and biological evaluation of 2-aminobenzanilide derivatives as potent and selective HDAC inhibitors.
ChemMedChem 2012;7(7):1256-66.
2012: Orazio Nicolotti; Marco Catto; Saverio Cellamare; M Convertino; F Leonetti; A Carotti
Estimation of the binding free energy by Linear Interaction Energy models.
Mini reviews in medicinal chemistry 2012;12(6):551-61.
2012: Angela Stefanachi; C Altomare; Marco Catto; Saverio Cellamare; F Leonetti; Orazio Nicolotti; L Pisani; Angelo Carotti
New strategies in the chemotherapy of leukemia: eradicating cancer stem cells in chronic myeloid leukemia.
Current cancer drug targets 2012;12(5):571-96.
2011: Sonja Schlimme; Diana A Stolfa; Lucia Altucci; Vincenzo Carafa; Angelo Carotti; Saverio Cellamare; Alexander-Thomas Hauser; Ralf Heinke; Manfred Jung; Srinivasaraghavan Kannan; Wolfgang Sippl
Carbamate prodrug concept for hydroxamate HDAC inhibitors.
ChemMedChem 2011;6(7):1193-8.
2011: F Leonetti; Orazio Nicolotti; L Pisani; Angela Stefanachi; Marco Catto; Saverio Cellamare; Angelo Carotti
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile.
Current medicinal chemistry 2011;18(19):2943-59.
2010: leonardo pisani; Marco Catto; Ilenia Giangreco; Francesco Leonetti; Orazio Nicolotti; Angela Stefanachi; Saverio Cellamare; Angelo Carotti
Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors.
ChemMedChem 2010;5(9):1616-30.
2010: Marco Catto; Rosaria Aliano; Angelo Carotti; Saverio Cellamare; Fausta Palluotto; Rosa Purgatorio; Angelo De Stradis; Francesco Campagna
Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as beta-amyloid aggregation inhibitors.
European journal of medicinal chemistry 2010;45(4):1359-66.
2008: Angela Stefanachi; Orazio Nicolotti; Francesco Leonetti; Saverio Cellamare; Francesco Campagna; Maria Isabel Loza; Jose Manuel Brea; Fernando Mazza; Enrico Gavuzzo; Angelo Carotti
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
Bioorganic & medicinal chemistry 2008;16(22):9780-9.
2008: Saverio Cellamare; Angela Stefanachi; Diana A Stolfa; Teodora Basile; Marco Catto; Francesco Campagna; Eddy Sotelo; Pasquale Acquafredda; Angelo Carotti
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Abeta1-40 aggregation in vitro.
Bioorganic & medicinal chemistry 2008;16(9):4810-22.
2007: Francesco Leonetti; Carmelida Capaldi; leonardo pisani; Orazio Nicolotti; Giovanni Muncipinto; Angela Stefanachi; Saverio Cellamare; Carla Caccia; Angelo Carotti
Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.
Journal of medicinal chemistry 2007;50(20):4909-16.
2005: Modesto de Candia; Paola Fossa; Saverio Cellamare; Luisa Mosti; Angelo Carotti; Cosimo Altomare
Insights into structure-activity relationships from lipophilicity profiles of pyridin-2(1H)-one analogs of the cardiotonic agent milrinone.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(1):78-86.
2004: Agostino De Marco; Modesto de Candia; Angelo Carotti; Saverio Cellamare; Erica De Candia; Cosimo Altomare
Lipophilicity-related inhibition of blood platelet aggregation by nipecotic acid anilides.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;22(2-3):153-64.
2003: Modesto de Candia; Luciana Summo; Antonio Carrieri; Cosimo Altomare; Adele Nardecchia; Saverio Cellamare; Angelo Carotti
Investigation of platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids.
Bioorganic & medicinal chemistry 2003;11(7):1439-50.
2003: Giuseppe Trapani; Andrea Latrofa; Massimo Franco; Antonio Carrieri; Saverio Cellamare; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(3-4):231-40.
2001: Angelo Carotti; Antonio Carrieri; Saverio Cellamare; F P Fanizzi; Enrico Gavuzzo; Fernando Mazza
Extended form of a retro-inverso peptide stabilized by beta-sheet unidirectional H-bonds: Crystallographic and NMR evidence.
Biopolymers 2001;60(4):322-32.
2000: Cosimo Altomare; Saverio Cellamare; Luciana Summo; Paola Fossa; Luisa Mosti; Angelo Carotti
Ionization behaviour and tautomerism-dependent lipophilicity of pyridine-2(1H)-one cardiotonic agents.
Bioorganic & medicinal chemistry 2000;8(5):909-16.
2000: Cosimo Altomare; Luciana Summo; Saverio Cellamare; Alexey V Varlamov; Leonid G Voskressensky; Tatiana N Borisova; Angelo Carotti
Pyrrolo[3,2-c]pyridine derivatives as inhibitors of platelet aggregation.
Bioorganic & medicinal chemistry letters 2000;10(6):581-4.
1999: Ilaria D'Acquarica; Francesco Gasparrini; Domenico Misiti; Claudio Villani; A Carotti; Saverio Cellamare; Sandra Muck
Direct chromatographic resolution of carnitine and O-acylcarnitine enantiomers on a teicoplanin-bonded chiral stationary phase.
Journal of chromatography. A 1999;857(1-2):145-55.
1999: Antonio Capurso; Vincenzo Solfrizzi; Francesco Panza; Franco Mastroianni; Francesco Torres; Angelo Del Parigi; Anna M Colacicco; Cristiano Capurso; G Nicoletti; B Veneziani; Saverio Cellamare; A Scalabrino
Increased bile acid excretion and reduction of serum cholesterol after crenotherapy with salt-rich mineral water.
Aging (Milan, Italy) 1999;11(4):273-6.
1998: Kevin St P McNaught; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; A Carotti; Bernard Testa; Peter Jenner; CD Marsden
Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease.
Biochemical pharmacology 1998;56(8):921-33.
1998: Cosimo Altomare; Saverio Cellamare; Luciana Summo; Marco Catto; Angelo Carotti; U Thull; Pierre-Alain Carrupt; Bernard Testa; H Stoeckli-Evans
Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: effects of lipophilicity and structure-activity relationships.
Journal of medicinal chemistry 1998;41(20):3812-20.
1996: Kevin St P McNaught; U Thull; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; Bernard Testa; Peter Jenner; CD Marsden
Nigral cell loss produced by infusion of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(3):265-74.
1996: Kevin St P McNaught; U Thull; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; Bernard Testa; Peter Jenner; CD Marsden
Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Biochemical pharmacology 1996;52(1):29-34.
1996: Kevin St P McNaught; U Thull; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; Bernard Testa; Peter Jenner; CD Marsden
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration.
Biochemical pharmacology 1996;51(11):1503-11.
1996: Kevin St P McNaught; U Thull; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; Bernard Testa; Peter Jenner; CD Marsden
Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Neuroscience letters 1996;206(1):37-40.
1996: Cosimo Altomare; Saverio Cellamare; Angelo Carotti; M L Barreca; Alba Chimirri; Anna Maria Monforte; Francesco Gasparrini; Claudio Villani; M Cirilli; F Mazza
Substituent effects on the enantioselective retention of anti-HIV 5-aryl-delta 2-1,2,4-oxadiazolines on R,R-DACH-DNB chiral stationary phase.
Chirality 1996;8(8):556-66.
1995: Kevin St P McNaught; U Thull; Pierre-Alain Carrupt; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; Bernard Testa; Peter Jenner; CD Marsden
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Biochemical pharmacology 1995;50(11):1903-11.
1995: Kevin St P McNaught; Cosimo Altomare; Saverio Cellamare; Angelo Carotti; U Thull; Pierre-Alain Carrupt; Bernard Testa; Peter Jenner; CD Marsden
Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Neuroreport 1995;6(8):1105-8.
1995: Angelo Carotti; Cosimo Altomare; Saverio Cellamare; Anna Maria Monforte; G Bettoni; Fulvio Loiodice; N Tangari; Vincenzo Tortorella
LFER and CoMFA studies on optical resolution of alpha-alkyl alpha-aryloxy acetic acid methyl esters on DACH-DNB chiral stationary phase.
Journal of computer-aided molecular design 1995;9(2):131-8.
1995: Cosimo Altomare; Saverio Cellamare; Angelo Carotti; G Casini; M Ferappi; Enrico Gavuzzo; F Mazza; P T Carrupt; P Gaillard; Bernard Testa
X-ray crystal structure, partitioning behavior, and molecular modeling study of piracetam-type nootropics: insights into the pharmacophore.
Journal of medicinal chemistry 1995;38(1):170-9.
1994: Cosimo Altomare; Angelo Carotti; Saverio Cellamare; A Carrieri; Romeo Ciabatti; A Malabarba
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships.
The Journal of pharmacy and pharmacology 1994;46(12):994-9.
1994: Cosimo Altomare; Saverio Cellamare; Angelo Carotti; M Ferappi
Linear solvation energy relationships in reversed-phase liquid chromatography. Examination of RP-8 stationary phases for measuring lipophilicity parameters.
Farmaco (Società chimica italiana : 1989) 1994;49(6):394-401.
1994: Cosimo Altomare; Francesco Campagna; V Carta; Saverio Cellamare; Angelo Carotti; G Genchi; G De Sarro
Synthesis, benzodiazepine receptor affinity and anticonvulsant activity of 5-H-indeno[1,2-c]pyridazine derivatives.
Farmaco (Società chimica italiana : 1989) 1994;49(5):313-23.
1994: H Van Gelderen; Joachim M Mayer; Saverio Cellamare; Bernard Testa
The temperature dependence of steady-state kinetics: what can be learned about pig liver esterase stereospecificity?
Chirality 1994;6(1):11-6.
1992: Cosimo Altomare; Angelo Carotti; G Casini; Saverio Cellamare; M Ferappi; C Vitali
Synthesis and structure-antimicrobial activity relationships of quaternary ammonium derivatives of perhydropyrrolo-[3,4-c]pyridine.
Arzneimittel-Forschung 1992;42(2):152-5.
1991: Cosimo Altomare; R S Tsai; N el Tayar; Bernard Testa; Angelo Carotti; Saverio Cellamare; Pier G De Benedetti
Determination of lipophilicity and hydrogen-bond donor acidity of bioactive sulphonyl-containing compounds by reversed-phase HPLC and centrifugal partition chromatography and their application to structure-activity relations.
The Journal of pharmacy and pharmacology 1991;43(3):191-7.
1990: Cosimo Altomare; Angelo Carotti; Saverio Cellamare; G Leogrande; D De Vito
Determination of antitubercular drugs in human plasma by HPLC through direct injection.
Farmaco (Società chimica italiana : 1989) 1990;45(11):1229-36.
1990: Cosimo Altomare; Angelo Carotti; G Casini; Saverio Cellamare; M Ferappi; G S Brigiani; M Persichella
Synthesis and pharmacological evaluation of perhydropyrrolo [3,4-c]pyridine derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(5):489-97.
1989: Cosimo Altomare; Angelo Carotti; Saverio Cellamare; M Ferappi
Benzenesulfonamide inhibitors of carbonic anhydrase: study of their hydrophobicity by RPLC.
Progress in clinical and biological research 1989;291():79-82.
1988: Cosimo Altomare; Angelo Carotti; G Casini; Saverio Cellamare; M Ferappi; Enrico Gavuzzo; F Mazza; Giancarlo Pantaleoni; R Giorgi
Synthesis and cognition activating properties of some mono- and bicyclic lactam derivatives.
Journal of medicinal chemistry 1988;31(11):2153-8.
1987: Cosimo Altomare; Angelo Carotti; Saverio Cellamare; M Ferappi
[ISRP in the determination of aryl esters of nipecotic acid in serum].
Bollettino chimico farmaceutico 1987;126(10):430-3.