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Lionel Henry Opie

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TOP 3
Lionel Henry Opie
Erythropoietin as a cardioprotective agent: down but not out.
Lionel Henry Opie; Sandrine Lecour
Delayed postconditioning: cardioprotection at the limit?
Joy McCarthy; Lionel Henry Opie; Michael N Sack; Amanda Lochner; M Faadiel Essop
PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition.

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All Publications

2011: Lionel Henry Opie
Erythropoietin as a cardioprotective agent: down but not out.
Heart (British Cardiac Society) 2011;97(19):1537-9.
2011: Lionel Henry Opie; Sandrine Lecour
Delayed postconditioning: cardioprotection at the limit?
Circulation 2011;124(12):1315-8.
2011: Joy McCarthy; Lionel Henry Opie; Michael N Sack; Amanda Lochner; M Faadiel Essop
PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition.
Journal of cellular physiology 2011;226(9):2457-68.
2011: Lionel Henry Opie
Inhibition of the cerebral renin-angiotensin system to limit cognitive decline in elderly hypertensive persons.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2011;25(4):277-9.
2011: Lionel Henry Opie
Glycaemia and heart failure in diabetes types 1 and 2.
Lancet 2011;378(9786):103-4.
2011: Lionel Henry Opie
Dilated cardiomyopathy and potentially deadly digoxin.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2011;101(6):388, 390.
2011: Lionel Henry Opie
Aspirin in the prevention of cancer.
Lancet 2011;377(9778):1651; author reply 1651-2.
2011: Kim T Lamont; Sarin Somers; Lydia Lacerda; Lionel Henry Opie; Sandrine Lecour
Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection.
Journal of pineal research 2011;50(4):374-80.
2011: Lionel Henry Opie; Derek M Yellon; Bernard J Gersh
Controversies in the cardiovascular management of type 2 diabetes.
Heart (British Cardiac Society) 2011;97(1):6-14.
2010: Roisin F Kelly; Kim T Lamont; Sarin Somers; DJ Hacking; Lydia Lacerda; Paul Thomas; Lionel Henry Opie; Sandrine Lecour
Ethanolamine is a novel STAT-3 dependent cardioprotective agent.
Basic research in cardiology 2010;105(6):763-70.
2010: Lydia Lacerda; Joy McCarthy; Shazia F K Mungly; Edward G Lynn; Michael N Sack; Lionel Henry Opie; Sandrine Lecour
TNFα protects cardiac mitochondria independently of its cell surface receptors.
Basic research in cardiology 2010;105(6):751-62.
2010: Tasneem Adam; Lionel Henry Opie; M Faadiel Essop
AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1.
Biochemical and biophysical research communications 2010;398(3):495-9.
2009: Dr L Lacerda; Sarin Somers; Lionel Henry Opie; Sandrine Lecour
Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway.
Cardiovascular research 2009;84(2):201-8.
2009: Lionel Henry Opie; Juhani Knuuti
The adrenergic-fatty acid load in heart failure.
Journal of the American College of Cardiology 2009;54(18):1637-46.
2009: Thomas A Gaziano; Lionel Henry Opie
Body-mass index and mortality.
Lancet 2009;374(9684):113-4; author reply 114.
2009: Lionel Henry Opie
Caloric restriction models reverse metabolic syndrome.
Journal of the American College of Cardiology 2009;53(10):899-900; author reply 900.
2009: Lionel Henry Opie
Perioperative beta blockade: the debate continues.
Lancet 2009;373(9664):627; author reply 628.
2009: Lionel Henry Opie
Hypertension, the changing pattern of drug usage.
Cardiovascular journal of Africa 2009;20(1):52-6.
2008: Miguel A Frias; Sarin Somers; Christine Gerber-Wicht; Lionel Henry Opie; Sandrine Lecour; Ursula Lang
The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis.
Cardiovascular research 2008;80(1):69-77.
2008: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Mika Scheinin; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy.
Circulation 2008;118(12):1250-8.
2008: Britt N Fuglesteg; Naushaad Suleman; Crina Tiron; Tambuzai Kanhema; Lydia Lacerda; Thomas Andreasen; Michael N Sack; Anne K Jonassen; Ole D Mjøs; Lionel Henry Opie; Sandrine Lecour
Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion.
Basic research in cardiology 2008;103(5):444-53.
2008: Naushaad Suleman; Sarin Somers; Robert Smith; Lionel Henry Opie; Sandrine C Lecour
Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning.
Cardiovascular research 2008;79(1):127-33.
2008: Lionel Henry Opie
Glucose-insulin-potassium therapy in patients with STEMI.
JAMA : the journal of the American Medical Association 2008;299(20):2385-6; author reply 2387-8.
2008: Eugene F Du Toit; A Genis; Lionel Henry Opie; P Pollesello; Amanda Lochner
A role for the RISK pathway and K(ATP) channels in pre- and post-conditioning induced by levosimendan in the isolated guinea pig heart.
British journal of pharmacology 2008;154(1):41-50.
2008: Lionel Henry Opie
Metabolic management of acute myocardial infarction comes to the fore and extends beyond control of hyperglycemia.
Circulation 2008;117(17):2172-7.
2008: Lionel Henry Opie
Beta-blockade should not be among several choices for initial therapy of hypertension.
Journal of hypertension 2008;26(2):161-3.
2007: Charles Shey Wiysonge; Jimmy Volmink; Lionel Henry Opie
Beta-blockers and the treatment of hypertension: it is time to move on.
Cardiovascular journal of Africa 2007;18(6):351-2.
2007: Lionel Henry Opie
Acute myocardial infarction and diabetes.
Lancet 2007;370(9588):634-5.
2007: Houman Ashrafian; Michael P Frenneaux; Lionel Henry Opie
Metabolic mechanisms in heart failure.
Circulation 2007;116(4):434-48.
2007: Lionel Henry Opie; Sandrine Lecour
The red wine hypothesis: from concepts to protective signalling molecules.
European heart journal 2007;28(14):1683-93.
2007: Graeme A Deuchar; Lionel Henry Opie; Sandrine Lecour
TNFalpha is required to confer protection in an in vivo model of classical ischaemic preconditioning.
Life sciences 2007;80(18):1686-91.
2007: Lionel Henry Opie
Metabolic syndrome.
Circulation 2007;115(3):e32-5.
2007: Charles Shey Wiysonge; Hazel A Bradley; Bongani M Mayosi; R Maroney; A Mbewu; Lionel Henry Opie; Jimmy Volmink
Beta-blockers for hypertension.
Cochrane database of systematic reviews (Online) 2007;(1):CD002003.
2007: Jan Minners; Dr L Lacerda; Derek M Yellon; Lionel Henry Opie; Christopher J McLeod; Michael N Sack
Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning.
Molecular and cellular biochemistry 2007;294(1-2):11-8.
2006: Lionel Henry Opie; Harry P Selker
Letter by Opie and Selker regarding article, "Reperfusion starts in the ambulance".
Circulation 2006;114(24):e640; author reply e641.
2006: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure.
Circulation 2006;114(20):2130-7.
2006: Dr L Lacerda; Robert M Smith; Lionel Henry Opie; Sandrine Lecour
TNFalpha-induced cytoprotection requires the production of free radicals within mitochondria in C2C12 myotubes.
Life sciences 2006;79(23):2194-201.
2006: Hazel A Bradley; Charles Shey Wiysonge; Jimmy Volmink; Bongani M Mayosi; Lionel Henry Opie
How strong is the evidence for use of beta-blockers as first-line therapy for hypertension? Systematic review and meta-analysis.
Journal of hypertension 2006;24(11):2131-41.
2006: Thomas A Gaziano; Lionel Henry Opie; Milton C Weinstein
Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysis.
Lancet 2006;368(9536):679-86.
2006: Lionel Henry Opie
Heart disease in Africa.
Lancet 2006;368(9534):449-50.
2006: Lionel Henry Opie
Donepezil for severe Alzheimer's disease.
Lancet 2006;368(9533):361-2; author reply 362.
2006: Lionel Henry Opie
Cardiologists are living through exciting times. The example of postconditioning to protect the human heart during revascularization.
Annales de cardiologie et d'angéiologie 2006;55(2):64-5.
2006: Y K Seedat; M A Croasdale; F J Milne; Lionel Henry Opie; Vicky Pinkney-Atkinson; B L Rayner; Y Veriava
South African hypertension guideline 2006.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2006;96(4 Pt 2):337-62.
2006: Sandrine Lecour; Peter Owira; Lionel Henry Opie
Ceramide-induced preconditioning involves reactive oxygen species.
Life sciences 2006;78(15):1702-6.
2006: Derek M Yellon; Lionel Henry Opie
Postconditioning for protection of the infarcting heart.
Lancet 2006;367(9509):456-8.
2006: Brian Rayner; Yvonne A Trinder; Donette Baines; Sedick Isaacs; Lionel Henry Opie
Effect of losartan versus candesartan on uric acid, renal function, and fibrinogen in patients with hypertension and hyperuricemia associated with diuretics.
American journal of hypertension 2006;19(2):208-13.
2006: Ségolène Gambert; Catherine Vergely; Rodolphe Filomenko; Daniel Moreau; Ali Bettaieb; Lionel Henry Opie; Luc Rochette
Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts.
Molecular and cellular biochemistry 2006;283(1-2):147-52.
2006: Lionel Henry Opie; Patrick J Commerford; Bernard J Gersh; Marc A Pfeffer
Controversies in ventricular remodelling.
Lancet 2006;367(9507):356-67.
2006: Stanley Nattel; Lionel Henry Opie
Controversies in atrial fibrillation.
Lancet 2006;367(9506):262-72.
2006: Norman M Kaplan; Lionel Henry Opie
Controversies in hypertension.
Lancet 2006;367(9505):168-76.
2006: Lionel Henry Opie; Patrick J Commerford; Bernard J Gersh
Controversies in stable coronary artery disease.
Lancet 2006;367(9504):69-78.
2006: Lionel Henry Opie
Controversies in cardiology.
Lancet 2006;367(9504):13-4.
2006: Sandrine Lecour; Elizabeth van der Merwe; Lionel Henry Opie; Michael N Sack
Ceramide attenuates hypoxic cell death via reactive oxygen species signaling.
Journal of cardiovascular pharmacology 2006;47(1):158-63.
2005: Sandrine Lecour; Naushaad Suleman; Graeme A Deuchar; Sarin Somers; Dr L Lacerda; Barbara Huisamen; Lionel Henry Opie
Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase).
Circulation 2005;112(25):3911-8.
2005: Thomas A Gaziano; Krisela Steyn; David J Cohen; Milton C Weinstein; Lionel Henry Opie
Cost-effectiveness analysis of hypertension guidelines in South Africa: absolute risk versus blood pressure level.
Circulation 2005;112(23):3569-76.
2005: Lionel Henry Opie; Yackoob K Seedat
Hypertension in sub-Saharan African populations.
Circulation 2005;112(23):3562-8.
2005: Lionel Henry Opie; Bongani M Mayosi
Cardiovascular disease in sub-Saharan Africa.
Circulation 2005;112(23):3536-40.
2005: Jakob Vinten-Johansen; Derek M Yellon; Lionel Henry Opie
Postconditioning: a simple, clinically applicable procedure to improve revascularization in acute myocardial infarction.
Circulation 2005;112(14):2085-8.
2005: Lionel Henry Opie
HIV/AIDS in South Africa.
Lancet 2005;366(9482):291.
2005: Lionel Henry Opie
Angiotensin receptor blockers and myocardial infarction: direct comparative studies are needed.
BMJ (Clinical research ed.) 2005;330(7502):1270; author reply 1270-1.
2005: Carl S Apstein; Lionel Henry Opie
A challenge to the metabolic approach to myocardial ischaemia.
European heart journal 2005;26(10):956-9.
2005: Siyanda Makaula; Amanda Lochner; Sonia Genade; Michael N Sack; Moneeb M Awan; Lionel Henry Opie
H-89, a non-specific inhibitor of protein kinase A, promotes post-ischemic cardiac contractile recovery and reduces infarct size.
Journal of cardiovascular pharmacology 2005;45(4):341-7.
2005: Lionel Henry Opie
ARBs and mortality in myocardial infarction.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 2005;16(2):84.
2005: Eugene F Du Toit; Ellen Rossouw; Ruduwaan Salie; Lionel Henry Opie; Amanda Lochner
Effect of sildenafil on reperfusion function, infarct size, and cyclic nucleotide levels in the isolated rat heart model.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2005;19(1):23-31.
2005: Sandrine Lecour; Luc Rochette; Lionel Henry Opie
Free radicals trigger TNF alpha-induced cardioprotection.
Cardiovascular research 2005;65(1):239-43.
2004: Lionel Henry Opie
The metabolic vicious cycle in heart failure.
Lancet 2004;364(9447):1733-4.
2004: Lionel Henry Opie
Cellular basis for therapeutic choices in heart failure.
Circulation 2004;110(17):2559-61.
2004: M Faadiel Essop; Lionel Henry Opie
Metabolic therapy for heart failure.
European heart journal 2004;25(20):1765-8.
2004: Lionel Henry Opie
Angina pectoris: the evolution of concepts.
Journal of cardiovascular pharmacology and therapeutics 2004;9 Suppl 1():S3-9.
2004: Robert M Smith; Naushaad Suleman; Dr L Lacerda; Lionel Henry Opie; Shizuo Akira; Kenneth R Chien; Michael N Sack
Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning.
Cardiovascular research 2004;63(4):611-6.
2004: Lionel Henry Opie; R Schall
Old antihypertensives and new diabetes.
Journal of hypertension 2004;22(8):1453-8.
2004: Brian Rayner; Hillel Goodman; Lionel Henry Opie
The chest radiograph. A useful investigation in the evaluation of hypertensive patients.
American journal of hypertension 2004;17(6):507-10.
2004: Birger Hesse; Christian Meyer; Flemming S Nielsen; Asako Sato; Jens D Hove; Søren Holm; Lia E Bang; Klaus F Kofoed; Tage Lysbo Svendsen; Hans-Henrik Parving; Lionel Henry Opie
Myocardial perfusion in type 2 diabetes with left ventricular hypertrophy: normalisation by acute angiotensin-converting enzyme inhibition.
European journal of nuclear medicine and molecular imaging 2004;31(3):362-8.
2003: Sandrine Lecour; Michael N Sack; Lionel Henry Opie
[Sphingolipid signaling: a potential pathway for TNF-alpha induced preconditioning].
Annales de cardiologie et d'angéiologie 2003;52(6):363-9.
2003: Lionel Henry Opie
Preconditioning and metabolic anti-ischaemic agents.
European heart journal 2003;24(20):1854-6.
2003: Lionel Henry Opie; Tony Dalby; D P Naidoo
Perindopril (Coversyl) prevents cardiovascular death and MI in coronary disease patients regardless of their cardiovascular risk.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 2003;14(5):277-9.
2003: Lionel Henry Opie
Errors: incompetence, ineptitude or failure.
Lancet 2003;362(9385):731.
2003: Lionel Henry Opie
Tedisamil in coronary disease: additional benefits in the therapy of atrial fibrillation?
Journal of cardiovascular pharmacology and therapeutics 2003;8 Suppl 1():S33-7.
2003: Brian Rayner; E Patricia Owen; Judy A King; Steven G Soule; Heleen Vreede; Lionel Henry Opie; David Marais; James S Davidson
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.
Journal of hypertension 2003;21(5):921-6.
2003: Lionel Henry Opie
Medicine and conflict.
Lancet 2003;361(9363):1130.
2002: Lionel Henry Opie; Matthias Haus; Patrick J Commerford; Basil N Levetan; Karen Moore; Johan Brink
Antihypertensive effects of angiotensin converting enzyme inhibition by lisinopril in post-transplant patients.
American journal of hypertension 2002;15(10 Pt 1):911-6.
2002: Lionel Henry Opie; Michael N Sack
Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning.
Journal of molecular and cellular cardiology 2002;34(9):1077-89.
2002: Gary D Lopaschuk; Lionel Henry Opie
Introduction to JMCC symposium on myocardial energy metabolism in health and disease.
Journal of molecular and cellular cardiology 2002;34(9):1075-6.
2002: Lionel Henry Opie; Hans-Henrik Parving
Diabetic nephropathy: can renoprotection be extrapolated to cardiovascular protection?
Circulation 2002;106(6):643-5.
2002: Brian Rayner; Biddy Buchanan-Lee; Johan Brink; Lionel Henry Opie
Generic substitution--is it safe in patients at high cardiovascular risk?
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2002;92(8):603-4.
2002: Lionel Henry Opie
The neuroendocrinology of congestive heart failure.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 2002;13(4):171-8.
2002: Lionel Henry Opie
What vitamins should I be taking?
The New England journal of medicine 2002;346(24):1914-6; author reply 1914-6.
2002: Jacques van Rooyen; J McCarthy; Lionel Henry Opie
Increased glycolysis during ischaemia mediates the protective effect of glucose and insulin in the isolated rat heart despite the presence of cardiodepressant exogenous substrates.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 2002;13(3):103-9.
2002: Sandrine Lecour; Robert M Smith; Brian Woodward; Lionel Henry Opie; Luc Rochette; Michael N Sack
Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection.
Journal of molecular and cellular cardiology 2002;34(5):509-18.
2002: Lionel Henry Opie; Robert Schall
Evidence-based evaluation of calcium channel blockers for hypertension: equality of mortality and cardiovascular risk relative to conventional therapy.
Journal of the American College of Cardiology 2002;39(2):315-22.
2001: Lionel Henry Opie
Renoprotection by angiotensin-receptor blockers and ACE inhibitors in hypertension.
Lancet 2001;358(9296):1829-31.
2001: Lionel Henry Opie
Calcium channel blockers in hypertension: reappraisal after new trials and major meta-analyses.
American journal of hypertension 2001;14(10):1074-81.
2001: E F Du Toit; J Meiring; Lionel Henry Opie
Relation of cyclic nucleotide ratios to ischemic and reperfusion injury in nitric oxide-donor treated rat hearts.
Journal of cardiovascular pharmacology 2001;38(4):529-38.
2001: Lionel Henry Opie; F H Messerli
The choice of first-line therapy: rationale for low-dose combinations of an angiotensin converting enzyme inhibitor and a diuretic.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2001;19(3):S17-21.
2001: Herzl Schwalb; A Olivson; J Li; Esther Houminer; Sayed E. Wahezi; Lionel Henry Opie; Dev Maulik; Joseph B Borman; Saul Powell
Nicorandil decreases postischemic actin oxidation.
Free radical biology & medicine 2001;31(5):607-14.
2001: Brian Rayner; J E Myers; Lionel Henry Opie; Yvonne A Trinder; James S Davidson
Screening for primary aldosteronism--normal ranges for aldosterone and renin in three South African population groups.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2001;91(7):594-9.
2001: L Rochette; D Moreau; Lionel Henry Opie
Effect of repeated regional myocardial ischemia in the rat heart on reperfusion arrhythmias and release of norepinephrine.
Journal of cardiovascular pharmacology 2001;38(1):78-89.
2001: Mohammad T Jaberansari; G F Baxter; C A Muller; S E Latouf; Erzsébet Röth; Lionel Henry Opie; D M Yellon
Angiotensin-converting enzyme inhibition enhances a subthreshold stimulus to elicit delayed preconditioning in pig myocardium.
Journal of the American College of Cardiology 2001;37(7):1996-2001.
2001: Lionel Henry Opie; Michael N Sack
Enhanced angiotensin II activity in heart failure: reevaluation of the counterregulatory hypothesis of receptor subtypes.
Circulation research 2001;88(7):654-8.
2001: Lionel Henry Opie
Blood-pressure-lowering treatment.
Lancet 2001;357(9257):717.
2001: B T Roverkamp; J Minners; Lionel Henry Opie
Opioid preconditioning extends to post-ischemic recovery of contractile function as shown with a novel opioid delta selective agonist, SB 235863A, that acts on the mitochondrial K(ATP) channel.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(1):89-90.
2000: S P Bell; M N Sack; A Patel; Lionel Henry Opie; Derek M Yellon
Delta opioid receptor stimulation mimics ischemic preconditioning in human heart muscle.
Journal of the American College of Cardiology 2000;36(7):2296-302.
2000: Lionel Henry Opie
First line drugs in chronic stable effort angina--the case for newer, longer-acting calcium channel blocking agents.
Journal of the American College of Cardiology 2000;36(6):1967-71.
2000: Lionel Henry Opie
Adverse cardiovascular drug interactions.
Current problems in cardiology 2000;25(9):621-76.
2000: Lionel Henry Opie; S Yusuf; W Kübler
Current status of safety and efficacy of calcium channel blockers in cardiovascular diseases: a critical analysis based on 100 studies.
Progress in cardiovascular diseases 2000;43(2):171-96.
2000: Moneeb M Awan; Siyanda Makaula; S Forresti; Michael N Sack; Lionel Henry Opie
Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart.
Molecular and cellular biochemistry 2000;211(1-2):111-21.
2000: Lionel Henry Opie
Diuretic downsides--but in low doses they still seem among the best authenticated antihypertensives.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2000;14(4):407-9.
2000: Jan Minners; E J van den Bos; Derek M Yellon; Herzl Schwalb; Lionel Henry Opie; Michael N Sack
Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: support for a mitochondrial role in cardioprotection.
Cardiovascular research 2000;47(1):68-73.
2000: Lionel Henry Opie
Trends in antihypertensive drug treatment.
Circulation 2000;101(21):E209.
2000: Lionel Henry Opie
Calcium channel blockers and preconditioning.
Journal of molecular and cellular cardiology 2000;32(5):859-60.
2000: Brian Rayner; Lionel Henry Opie; James S Davidson
The aldosterone/renin ratio as a screening test for primary aldosteronism.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2000;90(4):394-400.
2000: K A Aitchison; G F Baxter; Moneeb M Awan; Robert M Smith; Derek M Yellon; Lionel Henry Opie
Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: implications for ischemic preconditioning.
Basic research in cardiology 2000;95(1):1-10; discussion 11.
2000: Michael N Sack; Robert M Smith; Lionel Henry Opie
Tumor necrosis factor in myocardial hypertrophy and ischaemia--an anti-apoptotic perspective.
Cardiovascular research 2000;45(3):688-95.
1999: Lionel Henry Opie
Cardiac metabolism in ischemic heart disease.
Archives des maladies du coeur et des vaisseaux 1999;92(12):1755-60.
1999: E F Du Toit; C A Muller; J McCarthy; Lionel Henry Opie
Levosimendan: effects of a calcium sensitizer on function and arrhythmias and cyclic nucleotide levels during ischemia/reperfusion in the Langendorff-perfused guinea pig heart.
The Journal of pharmacology and experimental therapeutics 1999;290(2):505-14.
1999: C S Apstein; Lionel Henry Opie
Glucose-insulin-potassium (GIK) for acute myocardial infarction: a negative study with a positive value.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1999;13(3):185-9.
1999: Lionel Henry Opie
Proof that glucose-insulin-potassium provides metabolic protection of ischaemic myocardium?
Lancet 1999;353(9155):768-9.
1999: Moneeb M Awan; C Taunyane; K A Aitchison; Derek M Yellon; Lionel Henry Opie
Normothermic transfer times up to 3 min will not precondition the isolated rat heart.
Journal of molecular and cellular cardiology 1999;31(3):503-11.
1998: Lionel Henry Opie
Trends in prescribing calcium-channel blockers.
Lancet 1998;352(9141):1708.
1998: Lionel Henry Opie
Pursuit of the role of free radicals in stunning.
Basic research in cardiology 1998;93(5):422.
1998: C A Muller; Lionel Henry Opie; CA Pineda; J McCarthy; V Kraljevic
Combination of a calcium antagonist, verapamil, with an angiotensin converting enzyme inhibitor, trandolapril, in experimental myocardial ischemia and reperfusion: antiarrhythmic and hemodynamic effects of chronic oral pretreatment.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(5):449-55.
1998: Lionel Henry Opie
Principles of combination therapy for hypertension: what we learn from the HOT and other studies--a personal point of view.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(5):425-9.
1998: Lionel Henry Opie
Nisoldipine was associated with increased risk of MI among hypertensive diabetic patients when compared with enalapril.
Evidence-based cardiovascular medicine 1998;2(3):76.
1998: Amanda Lochner; Sonia Genade; E Tromp; Lionel Henry Opie; Johannes A Moolman; S Thomas; T Podzuweit
Role of cyclic nucleotide phosphodiesterases in ischemic preconditioning.
Molecular and cellular biochemistry 1998;186(1-2):169-75.
1998: Lionel Henry Opie
Review of trials in the treatment of coronary artery disease: theoretical expectations versus lack of practical success--how can we explain the differences?
The American journal of cardiology 1998;82(3A):15H-20H.
1998: L M King; Lionel Henry Opie
Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow.
Cardiovascular research 1998;39(2):381-92.
1998: Lionel Henry Opie
Personal viewpoint: new developments in the therapy of diabetic hypertensive disease. The ABCD study adds to strong evidence favoring the prime use of ACE inhibitors. Appropriate Blood Pressure Control in Diabetes.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(3):233-8.
1998: C A Muller; Lionel Henry Opie; J McCarthy; D Hofmann; CA Pineda; M Peisach
Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise.
Journal of the American College of Cardiology 1998;32(1):268-74.
1998: Lionel Henry Opie
Myocardial stunning--we do not know the mechanism nor is there "overwhelming evidence" for a major role of free radicals.
Basic research in cardiology 1998;93(3):152-5.
1998: Eugene F Du Toit; J McCarthy; J Miyashiro; Lionel Henry Opie; F Brunner
Effect of nitrovasodilators and inhibitors of nitric oxide synthase on ischaemic and reperfusion function of rat isolated hearts.
British journal of pharmacology 1998;123(6):1159-67.
1998: L M King; Lionel Henry Opie
Glucose and glycogen utilisation in myocardial ischemia--changes in metabolism and consequences for the myocyte.
Molecular and cellular biochemistry 1998;180(1-2):3-26.
1998: Friedrich Brunner; Lionel Henry Opie
Role of endothelin-A receptors in ischemic contracture and reperfusion injury.
Circulation 1998;97(4):391-8.
1998: Lionel Henry Opie
JNC VI guidelines.
Lancet 1998;351(9098):289; author reply 289-90.
1997: Lionel Henry Opie
Evidence is needed that beta blockade alone reduces mortality in hypertension.
BMJ (Clinical research ed.) 1997;315(7121):1544.
1997: Lionel Henry Opie
New developments in cardiovascular drugs: vitamin E and antioxidants--an informal and personal viewpoint.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1997;11(6):719-21.
1997: Lionel Henry Opie
New developments in cardiovascular drugs: heart failure--an informal and personal viewpoint.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1997;11(4):519-20.
1997: Lionel Henry Opie; B Hesse
Radionuclide tracers in the evaluation of resting myocardial ischaemia and viability.
European journal of nuclear medicine 1997;24(9):1183-93.
1997: Johannes A Moolman; Sonia Genade; E Tromp; Lionel Henry Opie; Amanda Lochner
Ischaemic preconditioning does not protect hypertrophied myocardium against ischaemia.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1997;87 Suppl 3():C151-6.
1997: Lionel Henry Opie
What does nisoldipine coat core (CC) add to current therapy that is clinically meaningful?
The American journal of cardiology 1997;79(10A):29-32; discussion 47-8.
1997: Lionel Henry Opie
Calcium channel blockers for hypertension: dissecting the evidence for adverse effects.
American journal of hypertension 1997;10(5 Pt 1):565-77.
1997: Lionel Henry Opie
Commentary: calcium antagonist controversy, does the accusing finger also point to beta-blockers and methyldopa?
Journal of human hypertension 1997;11(4):201-4.
1997: Lionel Henry Opie
New developments in the calcium channel antagonist controversy.
Circulation 1997;95(6):1668-70.
1997: Lionel Henry Opie; FO Müller; D P Myburgh; C Rosendorff; P Sareli; Yackoob K Seedat; D J Weich; H G Luus
Efficacy and tolerability of nisoldipine coat-core formulation in the treatment of essential hypertension: The South African Multicenter ANCHOR Study. Ambulatory Nisoldipine Coat-Core Hypertension Outpatient Response (ANCHOR) Investigators.
American journal of hypertension 1997;10(3):250-60.
1997: Amanda Lochner; Barbara Huisamen; J F Klopper; Lionel Henry Opie; L King; Eugene F Du Toit
Myocardial metabolism--Part I. Round-table discussion.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1997;87 Suppl 1():C45-53.
1997: Lionel Henry Opie
Preconditioning: we do not need more experiments, because our current knowledge already permits us to develop pharmacological agents.
Basic research in cardiology 1997;92 Suppl 2():46-7.
1997: Lionel Henry Opie
Calcium channel blockers: summary and safety issues.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1997;10 Suppl 3():893-5.
1997: Lionel Henry Opie; T F Lüscher; R Ferrari; J F Hansen
How European cardiologists perceive the role of calcium antagonists in follow-up after myocardial infarction.
European heart journal 1997;18 Suppl A():A134-8.
1997: Lionel Henry Opie
Mechanisms whereby calcium channel antagonists may protect patients with coronary artery disease.
European heart journal 1997;18 Suppl A():A92-104.
1997: Lionel Henry Opie
Pharmacological differences between calcium antagonists.
European heart journal 1997;18 Suppl A():A71-9.
1996: Lionel Henry Opie
The multifarious spectrum of ischemic left ventricular dysfunction: relevance of new ischemic syndromes.
Journal of molecular and cellular cardiology 1996;28(12):2403-14.
1996: L M King; Lionel Henry Opie
Does preconditioning act by glycogen depletion in the isolated rat heart?
Journal of molecular and cellular cardiology 1996;28(12):2305-21.
1996: Lionel Henry Opie
Myocardial ischemia, reperfusion and cytoprotection.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 1996;15(10):703-8.
1996: Lionel Henry Opie
The STONE Study (Shanghai Trial of Hypertension in the Elderly): a meeting report.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1996;10(4):467-8.
1996: Lionel Henry Opie
Calcium channel antagonists should be among the first-line drugs in the management of cardiovascular disease.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1996;10(4):455-61.
1996: Lionel Henry Opie
Hypertension 1996--simplified guidelines for primary care nurses and medical students.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1996;86(4):357-8.
1996: Lionel Henry Opie
ACE inhibitors in pregnancy--how to avoid the sting in the tail.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1996;86(4):326-7.
1996: H R Cross; Lionel Henry Opie; George K Radda; Kieran Clarke
Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved.
Circulation research 1996;78(3):482-91.
1996: L M King; Lionel Henry Opie
Preconditioning--a reappraisal of protection.
Basic research in cardiology 1996;91(1):5-7.
1996: Lionel Henry Opie
Calcium channel antagonists in the management of anginal syndromes: changing concepts in relation to the role of coronary vasospasm.
Progress in cardiovascular diseases 1996;38(4):291-314.
1996: Lionel Henry Opie
Calcium channel antagonists in the treatment of coronary artery disease: fundamental pharmacological properties relevant to clinical use.
Progress in cardiovascular diseases 1996;38(4):273-90.
1995: C J Quarmby; V C Burch; David M Dent; Lionel Henry Opie
Conn's syndrome due to adrenocortical adenoma--a rare but rewarding cause of curable hypertension.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1995;85(12 Pt 2):1353-6.
1995: Lionel Henry Opie; Krisela Steyn
Rationale for the hypertension guidelines for primary care in South Africa.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1995;85(12 Pt 2):1325-8, 1330-1, 1334-5 passim.
1995: Lionel Henry Opie
Risks and benefits of calcium antagonists.
Lancet 1995;346(8980):961.
1995: Friedrich Brunner; H Stessel; N Watzinger; B M Löffler; Lionel Henry Opie
Binding of endothelin to plasma proteins and tissue receptors: effects on endothelin determination, vasoactivity, and tissue kinetics.
FEBS letters 1995;373(1):97-101.
1995: Lionel Henry Opie; F H Messerli
Nifedipine and mortality. Grave defects in the dossier.
Circulation 1995;92(5):1068-73.
1995: Lionel Henry Opie; F Boucher
Trimetazidine and myocardial ischemic contracture in isolated rat heart.
The American journal of cardiology 1995;76(6):38B-40B.
1995: Lionel Henry Opie
New concepts regarding events that lead to myocardial infarction.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9 Suppl 3():479-87.
1995: Lionel Henry Opie
Chronic stunning: the new switch in thought.
Basic research in cardiology 1995;90(4):303-4.
1995: Lionel Henry Opie; H Kowolik
The discovery of captopril: from large animals to small molecules.
Cardiovascular research 1995;30(1):18-25.
1995: H R Cross; Kieran Clarke; Lionel Henry Opie; George K Radda
Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate?
Journal of molecular and cellular cardiology 1995;27(7):1369-81.
1995: Lionel Henry Opie
Glucose and the metabolism of ischaemic myocardium.
Lancet 1995;345(8964):1520-1.
1995: Lionel Henry Opie
Fundamental role of angiotensin-converting enzyme inhibitors in the management of congestive heart failure.
The American journal of cardiology 1995;75(18):3F-6F.
1995: Lionel Henry Opie
Regulation of myocardial contractility.
Journal of cardiovascular pharmacology 1995;26 Suppl 1():S1-9.
1995: L M King; F Boucher; Lionel Henry Opie
Coronary flow and glucose delivery as determinants of contracture in the ischemic myocardium.
Journal of molecular and cellular cardiology 1995;27(1):701-20.
1995: Friedrich Brunner; R Mouton; Amanda Lochner; Lionel Henry Opie
Defective stretch-induced release of atrial natriuretic peptide from aging hypertensive rat heart: possible role of phosphatidylinositol pathway.
Journal of cardiovascular pharmacology 1995;25(1):168-76.
1995: Lionel Henry Opie
Risk factors for heart disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1995;85(1):49-50.
1994: B Huisamen; R Mouton; Lionel Henry Opie; Amanda Lochner
Effects of ischaemia, reperfusion and alpha 1-adrenergic receptor stimulation on the inositoltrisphosphate receptor population in rat heart atria and ventricles.
Molecular and cellular biochemistry 1994;140(1):23-30.
1994: Udho Thadani; Lionel Henry Opie
Nitrates for unstable angina.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8(5):719-26.
1994: E F du Toit; Lionel Henry Opie
Inhibitors of Ca2+ ATPase pump of sarcoplasmic reticulum attenuate reperfusion stunning in isolated rat heart.
Journal of cardiovascular pharmacology 1994;24(4):678-84.
1994: R Enous; Lionel Henry Opie
Effect of the angiotensin-converting enzyme inhibitor, perindoprilat, and of angiotensin-II on the transient inward current of rabbit ventricular myocytes.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8(4):647-51.
1994: Lionel Henry Opie
Myocardial stunning--are calcium antagonists useful?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8 Suppl 3():533-41.
1994: Lionel Henry Opie
Potassium channels.
Cardiovascular research 1994;28(7):1119-20.
1994: C A Muller; Lionel Henry Opie; M Peisach; C A Pineda
Chronic oral pretreatment with the angiotensin converting enzyme inhibitor, trandolapril decreases ventricular fibrillation in acute ischaemia and reperfusion.
European heart journal 1994;15(7):988-96.
1994: François Boucher; D J Hearse; Lionel Henry Opie
Effects of trimetazidine on ischemic contracture in isolated perfused rat hearts.
Journal of cardiovascular pharmacology 1994;24(1):45-9.
1994: Lionel Henry Opie
The new trials: AIRE, ISIS-4, and GISSI-3. Is the dossier on ACE inhibitors and myocardial infarction now complete?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8(3):469-72.
1994: Lionel Henry Opie
Margarine and coronary heart disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1994;84(6):357, 359.
1994: E F du Toit; Lionel Henry Opie
Antiarrhythmic properties of specific inhibitors of sarcoplasmic reticulum calcium ATPase in the isolated perfused rat heart after coronary artery ligation.
Journal of the American College of Cardiology 1994;23(6):1505-10.
1994: Lionel Henry Opie
The ever expanding spectrum of ischemic left ventricular dysfunction.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8 Suppl 2():297-304.
1994: B Huisamen; R Mouton; Lionel Henry Opie; Amanda Lochner
Demonstration of a specific [3H]INS(1,4,5)P3 binding site in rat heart sarcoplasmic reticulum.
Journal of molecular and cellular cardiology 1994;26(3):341-9.
1994: M F Oliver; Lionel Henry Opie
Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias.
Lancet 1994;343(8890):155-8.
1993: D Hofmann; Lionel Henry Opie
Potassium channel blockade and acute myocardial infarction: implications for management of the non-insulin requiring diabetic patient.
European heart journal 1993;14(12):1585-9.
1993: E F du Toit; Lionel Henry Opie
Role for the Na+/H+ exchanger in reperfusion stunning in isolated perfused rat heart.
Journal of cardiovascular pharmacology 1993;22(6):877-83.
1993: Lionel Henry Opie
The mechanism of myocyte death in ischaemia.
European heart journal 1993;14 Suppl G():31-3.
1993: Lionel Henry Opie
Cholesterol confusion in primary prevention of coronary artery disease.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7(5):779-84.
1993: Lionel Henry Opie
Interactions with cardiovascular drugs.
Current problems in cardiology 1993;18(9):531-81.
1993: Lionel Henry Opie
South Africa's health service.
Lancet 1993;342(8868):441.
1993: Lionel Henry Opie
Modulation of ischemia by regulation of the ATP-sensitive potassium channel.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7 Suppl 3():507-13.
1993: Lionel Henry Opie
The origin and significance of our supplements--a response to the New England Journal of Medicine.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7 Suppl 3():491-2.
1993: P Owen; E F du Toit; Lionel Henry Opie
The optimal glucose concentration for intermittent cardioplegia in isolated rat heart when added to St. Thomas' Hospital cardioplegic solution.
The Journal of thoracic and cardiovascular surgery 1993;105(6):995-1006.
1993: M G Worthington; M C Wendt; Lionel Henry Opie
Sodium transport in hypertension: assessment of membrane-associated defects in South African black and white hypertensives.
Journal of human hypertension 1993;7(3):291-7.
1993: T Podzuweit; A Müller; Lionel Henry Opie
Anti-arrhythmic effects of selective inhibition of myocardial phosphodiesterase II.
Lancet 1993;341(8847):760.
1993: Lionel Henry Opie
Calcium antagonists for congestive heart failure: is it really one bridge too far to cross?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7(1):93-4.
1993: Lionel Henry Opie
Individualised selection of antihypertensive therapy.
Drugs 1993;46 Suppl 2():142-8.
1992: A van Zyl; A A Jennings; M J Byrne; Lionel Henry Opie
Effects of therapy on renal impairment in essential hypertension.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1992;82(6):407-10.
1992: Lionel Henry Opie
Treatment of hypertension in the elderly--the end of the story?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(6):559-62; discussion 563-4.
1992: M G Worthington; Lionel Henry Opie
Effects of calcium channel agonism by Bay-K-8644 on ventricular fibrillation threshold of isolated heart.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(6):597-604.
1992: F Brunner; E F du Toit; Lionel Henry Opie
Endothelin release during ischaemia and reperfusion of isolated perfused rat hearts.
Journal of molecular and cellular cardiology 1992;24(11):1291-305.
1992: Lionel Henry Opie; E Carmeliet
Introduction to the special issue on potassium channels.
Cardiovascular research 1992;26(11):1010.
1992: Lionel Henry Opie; P Owen; E du Toit; G G Norton
Decreased rates of release of atrial natriuretic peptide from isolated hearts from aging hypertensive rats.
American journal of hypertension 1992;5(10):748-53.
1992: M G Worthington; Lionel Henry Opie
Contrasting effects of cyclic AMP increase caused by beta-adrenergic stimulation or by adenylate cyclase activation on ventricular fibrillation threshold of isolated rat heart.
Journal of cardiovascular pharmacology 1992;20(4):595-600.
1992: Lionel Henry Opie
Cardiac metabolism--emergence, decline, and resurgence. Part II.
Cardiovascular research 1992;26(9):817-30.
1992: Lionel Henry Opie
Cardiac metabolism--emergence, decline, and resurgence. Part I.
Cardiovascular research 1992;26(8):721-33.
1992: Lionel Henry Opie; P G Camici
Myocardial blood flow, deoxyglucose uptake, and myocyte viability in ischemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(7):1353-6.
1992: W A Coetzee; Lionel Henry Opie
Effects of oxygen free radicals on isolated cardiac myocytes from guinea-pig ventricle: electrophysiological studies.
Journal of molecular and cellular cardiology 1992;24(6):651-63.
1992: C A Muller; Lionel Henry Opie; C A Pineda; M Peisach
Bucindolol, a beta blocker, decreased ventricular fibrillation and maintained mechanical function in a pig model of acute myocardial ischemia.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(3):233-7.
1992: W F Lubbe; T Podzuweit; Lionel Henry Opie
Potential arrhythmogenic role of cyclic adenosine monophosphate (AMP) and cytosolic calcium overload: implications for prophylactic effects of beta-blockers in myocardial infarction and proarrhythmic effects of phosphodiesterase inhibitors.
Journal of the American College of Cardiology 1992;19(7):1622-33.
1992: E F du Toit; Lionel Henry Opie
Modulation of severity of reperfusion stunning in the isolated rat heart by agents altering calcium flux at onset of reperfusion.
Circulation research 1992;70(5):960-7.
1992: C A Muller; Lionel Henry Opie; M Peisach; C A Pineda
Antiarrhythmic effects of the angiotensin converting enzyme inhibitor perindoprilat in a pig model of acute regional myocardial ischemia.
Journal of cardiovascular pharmacology 1992;19(5):748-54.
1992: Lionel Henry Opie
Choice of ACE inhibitor for congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(2):181.
1992: Lionel Henry Opie; J Z Przybojewski
Angiotensin-converting enzyme inhibitor therapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1992;81(4):183-5.
1992: J Wilson; P J Commerford; R S Millar; Lionel Henry Opie
Hemodynamic effects of nisoldipine, a highly specific calcium antagonist, in patients with acute myocardial infarction.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(1):41-6.
1992: Lionel Henry Opie
Should calcium antagonists be used after myocardial infarction? Ischemia selectivity versus vascular selectivity.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1992;6(1):19-24.
1992: Lionel Henry Opie
Myocardial stunning: a role for calcium antagonists during reperfusion?
Cardiovascular research 1992;26(1):20-4.
1992: R Enous; W A Coetzee; Lionel Henry Opie
Effects of the ACE inhibitor, perindoprilat, and of angiotensin II on the transient inward current of guinea pig ventricular myocytes.
Journal of cardiovascular pharmacology 1992;19(1):17-23.
1992: Lionel Henry Opie
Choosing the correct drug for the individual hypertensive patient.
Drugs 1992;44 Suppl 1():147-55.
1992: Lionel Henry Opie; E F du Toit
Postischemic stunning: the two-phase model for the role of calcium as pathogen.
Journal of cardiovascular pharmacology 1992;20 Suppl 5():S1-4.
1991: Lionel Henry Opie
Sublingual nifedipine.
Lancet 1991;338(8776):1203.
1991: Ulrich O von Oppell; L M King; E F Du Toit; P Owen; Bruno Reichart; Lionel Henry Opie
Effect of pH shifts induced by oxygenating crystalloid cardioplegic solutions.
The Annals of thoracic surgery 1991;52(4):903-7.
1991: Lionel Henry Opie
Postischemic stunning--the case for calcium as the ultimate culprit.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5(5):895-9.
1991: E Schneider; A A Jennings; Lionel Henry Opie
Captopril, nifedipine and their combination for therapy of hypertensive urgencies.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1991;80(6):265-70.
1991: Ulrich O von Oppell; L M King; E F Du Toit; P Owen; Bruno Reichart; Lionel Henry Opie
Effect of oxygenation and consequent pH changes on the efficacy of St. Thomas' Hospital cardioplegic solution.
The Journal of thoracic and cardiovascular surgery 1991;102(3):396-404.
1991: Ulrich O von Oppell; E F Du Toit; L M King; P Owen; T Dunne; Bruno Reichart; Lionel Henry Opie
St. Thomas' Hospital cardioplegic solution. Beneficial effect of glucose and multidose reinfusions of cardioplegic solution.
The Journal of thoracic and cardiovascular surgery 1991;102(3):405-12.
1991: S C Dennis; W Gevers; Lionel Henry Opie
Protons in ischemia: where do they come from; where do they go to?
Journal of molecular and cellular cardiology 1991;23(9):1077-86.
1991: Lionel Henry Opie
Calcium antagonists post-infarction: the significance of experimental studies on potentially lethal early ischemic ventricular arrhythmias.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5(4):671-5.
1991: Jan Willem De Jong; P Van der Meer; P Owen; Lionel Henry Opie
Prevention and treatment of ischemic injury with nucleosides.
Bratislavské lekárske listy 1991;92(3-4):165-73.
1991: Lionel Henry Opie
Role of calcium and other ions in reperfusion injury.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5 Suppl 2():237-47.
1991: Lionel Henry Opie
Reperfusion injury--fad, fashion, or fact?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5 Suppl 2():223-4.
1991: D H Boehm; Paul Human; Ulrich O von Oppell; P Owen; Hermann Reichenspurner; Lionel Henry Opie; A G Rose; Bruno Reichart
Adenosine cardioplegia: reducing reperfusion injury of the ischaemic myocardium?
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1991;5(10):542-5.
1991: Lionel Henry Opie
Calcium antagonists, ventricular arrhythmias, and sudden cardiac death: a major challenge for the future.
Journal of cardiovascular pharmacology 1991;18 Suppl 10():S81-6.
1991: Lionel Henry Opie
Required beta blocker profile in the elderly.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;4 Suppl 6():1273-80.
1991: Lionel Henry Opie
Profiles of calcium antagonists in cardiovascular disease with special reference to second-generation agents and amlodipine.
Postgraduate medical journal 1991;67 Suppl 5():S2-8.
1990: Lionel Henry Opie
Compensation and overcompensation in congestive heart failure.
American heart journal 1990;120(6 Pt 2):1552-7.
1990: V Strugo; F J Glew; J Davis; Lionel Henry Opie
Update: Recommendations for human blood pressure determination by sphygmomanometers.
Hypertension 1990;16(5):594.
1990: Jan Willem De Jong; P van der Meer; H van Loon; P Owen; Lionel Henry Opie
Adenosine as adjunct to potassium cardioplegia: effect on function, energy metabolism, and electrophysiology.
The Journal of thoracic and cardiovascular surgery 1990;100(3):445-54.
1990: Antoine Bril; L Rochette; A Verry; Véronique Maupoil; Ricky Y K Man; Lionel Henry Opie
Effects of the free radical generating system FeCl3/ADP on reperfusion arrhythmias of rat hearts and electrical activity of canine Purkinje fibres.
Cardiovascular research 1990;24(8):669-75.
1990: Lionel Henry Opie
What is new in myocardial ischemia?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1990;4 Suppl 4():765-6.
1990: W A Coetzee; R Enous; Lionel Henry Opie
Trimetazidine: effects on delayed afterdepolarizations (DADs) and upstroke velocity of the action potential.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1990;4 Suppl 4():806-7.
1990: Lionel Henry Opie
Myocardial ischemia--metabolic pathways and implications of increased glycolysis.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1990;4 Suppl 4():777-90.
1990: Daniel Moreau; L Rochette; J P Didier; Lionel Henry Opie; J Bralet
Effects of increased heart work on release of norepinephrine and ventricular arrhythmias following reperfusion in the isolated rat heart.
Journal of cardiovascular pharmacology 1990;15(6):927-32.
1990: Ian Harper; E van der Merwe; P Owen; Lionel Henry Opie
Ultrastructural correlates of ischaemic contracture during global subtotal ischaemia in the rat heart.
Journal of experimental pathology (Oxford, England) 1990;71(2):257-68.
1990: D H Boehm; Paul Human; Hermann Reichenspurner; Ulrich O von Oppell; P Owen; Lionel Henry Opie; Bruno Reichart
Adenosine and its role in cardioplegia: effects on postischemic recovery in the baboon.
Transplantation proceedings 1990;22(2):545-6.
1990: Steven C Dennis; W A Coetzee; E J Cragoe; Lionel Henry Opie
Effects of proton buffering and of amiloride derivatives on reperfusion arrhythmias in isolated rat hearts. Possible evidence for an arrhythmogenic role of Na(+)-H+ exchange.
Circulation research 1990;66(4):1156-9.
1990: W A Coetzee; P Owen; Steven C Dennis; S Saman; Lionel Henry Opie
Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias.
Cardiovascular research 1990;24(2):156-64.
1990: P Owen; S Dennis; Lionel Henry Opie
Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts.
Circulation research 1990;66(2):344-54.
1990: P F Kantor; W A Coetzee; E E Carmeliet; Steven C Dennis; Lionel Henry Opie
Reduction of ischemic K+ loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea.
Circulation research 1990;66(2):478-85.
1990: Lionel Henry Opie; W T Clusin
Cellular mechanism for ischemic ventricular arrhythmias.
Annual review of medicine 1990;41():231-8.
1989: T Schubert; H Vetter; P Owen; Bruno Reichart; Lionel Henry Opie
Adenosine cardioplegia. Adenosine versus potassium cardioplegia: effects on cardiac arrest and postischemic recovery in the isolated rat heart.
The Journal of thoracic and cardiovascular surgery 1989;98(6):1057-65.
1989: P Camici; Ele Ferrannini; Lionel Henry Opie
Myocardial metabolism in ischemic heart disease: basic principles and application to imaging by positron emission tomography.
Progress in cardiovascular diseases 1989;32(3):217-38.
1989: Lionel Henry Opie
Myocardial ischaemia and coronary artery disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;Suppl():1-5.
1989: Lionel Henry Opie
Reperfusion injury and its pharmacologic modification.
Circulation 1989;80(4):1049-62.
1989: Lionel Henry Opie; P J Commerford; C Adnams
Effects of calcium antagonists on hypertension and diastolic function.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;76(3):89-92.
1989: Lionel Henry Opie
The total costs and demands of treatment of hypertension in South Africa. Contributions of drug costs, hidden costs and mass strategies.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;76(3):85-8.
1989: Lionel Henry Opie
Calcium channel antagonists: Part VI: Clinical pharmacokinetics of first and second-generation agents.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3(4):482-97.
1989: Lionel Henry Opie; W P Leary; P J Commerford; D Davey; P Joubert; P Marshall; J Milne; C Rosendorff; M Seedat; Y K Seedat
Calcium antagonists in hypertension.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;76(2):76-7.
1989: D Posel; T Noakes; P Kantor; M Lambert; Lionel Henry Opie
Exercise training after experimental myocardial infarction increases the ventricular fibrillation threshold before and after the onset of reinfarction in the isolated rat heart.
Circulation 1989;80(1):138-45.
1989: Lionel Henry Opie
Pharmacology of acute effort angina.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3 Suppl 1():257-70.
1989: J H Chesebro; Lionel Henry Opie; V Fuster
The recent trials for aspirin in the prevention of cardiovascular mortality.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3(3):353-4.
1989: Lionel Henry Opie
Proposed role of calcium in reperfusion injury.
International journal of cardiology 1989;23(2):159-64.
1989: Lionel Henry Opie
Digoxin revived?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3(1):11-2.
1989: C A Muller; Lionel Henry Opie; M Peisach; C A Pineda; C W Hamm; F T Thandroyen
Critical role of dose in protection by propranolol against ventricular fibrillation in a pig model of acute myocardial ischemia.
Journal of cardiovascular pharmacology 1989;13(2):192-7.
1989: Steven C Dennis; W A Coetzee; J W de Jong; W Clusin; Lionel Henry Opie
Effects of coronary flow, pacing rate, isoprenaline and diltiazem on ischemic ventricular arrhythmias in guinea pig hearts.
The Journal of pharmacology and experimental therapeutics 1989;248(1):372-7.
1989: S A Boschmans; M F Perkin; Stephanus Terblanche; Lionel Henry Opie
The effects of imipramine, mianserin and trazodone on the chronotropic, inotropic and coronary vascular responses in the isolated perfused rat heart.
General pharmacology 1989;20(2):233-7.
1989: A I van Zyl; A A Jennings; E D Bateman; Lionel Henry Opie
Comparison of respiratory effects of two cardioselective beta-blockers, celiprolol and atenolol, in asthmatics with mild to moderate hypertension.
Chest 1989;95(1):209-13.
1989: Lionel Henry Opie
Digitalis--still problematic?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;2(6):715.
1988: A Keren; P Dorian; J M Davy; Lionel Henry Opie
Effects of magnesium on ischemic and reperfusion arrhythmias in the rat heart and electrophysiologic effects of hypermagnesemia in the anesthetized dog.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(5):637-45.
1988: Lionel Henry Opie; W A Coetzee
Role of calcium ions in reperfusion arrhythmias: relevance to pharmacologic intervention.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(5):623-36.
1988: Lionel Henry Opie
Role of vasodilation in the antihypertensive and antianginal effects of labetalol: implications for therapy of combined hypertension and angina.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(3):369-76.
1988: E A Lloyd; R G Charles; G D Gordon; C M Adams; T A Mabin; P J Commerford; Lionel Henry Opie
Beta-blockade by sotalol in early myocardial infarction decreases ventricular arrhythmias without increasing left ventricular volume.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1988;74(1):5-10.
1988: C A Muller; Lionel Henry Opie; C W Hamm; M Peisach; C A Pineda; F T Thandroyen
Verapamil and tiapamil in prevention of ventricular fibrillation in pigs with coronary ligation. Comparative effects on left ventricular function.
Circulation 1988;78(1):227-32.
1988: Lionel Henry Opie
Calcium channel antagonists. Part V: Second-generation agents.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(2):191-203.
1988: Lionel Henry Opie
Calcium channel antagonists. Part IV: Side effects and contraindications drug interactions and combinations.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(2):177-89.
1988: Lionel Henry Opie
Calcium channel antagonists. Part III: Use and comparative efficacy in hypertension and supraventricular arrhythmias. Minor indications.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;1(6):625-56.
1988: W Coetzee; G Biermans; Geert Callewaert; J Vereecke; Lionel Henry Opie; Edward Carmeliet
The effect of inhibition of mitochondrial energy metabolism on the transient inward current of isolated guinea-pig ventricular myocytes.
Journal of molecular and cellular cardiology 1988;20(3):181-5.
1988: Lionel Henry Opie
Qualities of an ideal beta-adrenoceptor antagonist and comparison of existing agents with a new cardioselective hydrophilic vasodilator beta-adrenoceptor antagonist, celiprolol.
The American journal of cardiology 1988;61(5):8C-13C.
1988: S Saman; W A Coetzee; Lionel Henry Opie
Inhibition by simulated ischemia or hypoxia of delayed afterdepolarizations provoked by cyclic AMP: significance for ischemic and reperfusion arrhythmias.
Journal of molecular and cellular cardiology 1988;20(2):91-5.
1988: F T Thandroyen; J McCarthy; K P Burton; Lionel Henry Opie
Ryanodine and caffeine prevent ventricular arrhythmias during acute myocardial ischemia and reperfusion in rat heart.
Circulation research 1988;62(2):306-14.
1988: Lionel Henry Opie; W A Coetzee; Steven C Dennis; F T Thandroyen
A potential role of calcium ions in early ischemic and reperfusion arrhythmias.
Annals of the New York Academy of Sciences 1988;522():464-77.
1988: Lionel Henry Opie; P J Commerford
The total vascular burden, peripheral and coronary: vasodilator effects of nifedipine.
American heart journal 1988;115(1 Pt 1):228-38.
1988: Lionel Henry Opie
Heart failure today.
Cardiology 1988;75 Suppl 1():155-8.
1988: Lionel Henry Opie
Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;1(5):461-91.
1988: Luc Rochette; J Yao-Kouame; J Bralet; Lionel Henry Opie
Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart.
Fundamental & clinical pharmacology 1988;2(5):385-97.
1988: Lionel Henry Opie
Inodilation--the way ahead in the early therapy of congestive heart failure?
Cardiology 1988;75 Suppl 1():138-47.
1988: Lionel Henry Opie
Sympathetic stimulation of ischemic myocardium: role of plasma free fatty acids and potassium.
Journal of cardiovascular pharmacology 1988;12 Suppl 1():S31-8.
1987: Lionel Henry Opie
Myocardial ischaemia--metabolism and its modification.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1987;72(11):740-7.
1987: Lionel Henry Opie
Calcium channel antagonists, Part I: Fundamental properties: mechanisms, classification, sites of action.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1987;1(4):411-30.
1987: Lionel Henry Opie
Torsades de pointes induced by sotalol.
The American journal of cardiology 1987;60(14):1216-7.
1987: W F Lubbe; Lionel Henry Opie
Metabolic basis of increased vulnerability to fibrillation in myocardial ischaemia.
Journal of molecular and cellular cardiology 1987;19 Suppl 5():1-3.
1987: W A Coetzee; Lionel Henry Opie; S Saman
Proposed role of energy supply in the genesis of delayed afterdepolarizations--implications for ischemic or reperfusion arrhythmias.
Journal of molecular and cellular cardiology 1987;19 Suppl 5():13-21.
1987: A R Daniels; Lionel Henry Opie
Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs.
The American journal of cardiology 1987;60(8):703-7.
1987: Lionel Henry Opie; F R Buhler; A Fleckenstein; L Hansson; D C Harrison; P A Poole-Wilson; A Schwartz; P M Vanhoutte; E Braunwald; W G Nayler
International Society and Federation of Cardiology: Working Group on Classification of Calcium Antagonists for Cardiovascular Disease.
The American journal of cardiology 1987;60(7):630-2.
1987: F T Thandroyen; N S Flint; M G Worthington; Lionel Henry Opie
Arrhythmogenic action of alpha 1-adrenoceptor stimulation in normoxic rat ventricular myocardium: influence of nisoldipine, reduced extracellular Ca2+ and ryanodine.
Journal of molecular and cellular cardiology 1987;19(9):841-51.
1987: W A Coetzee; Lionel Henry Opie
Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle.
Circulation research 1987;61(2):157-65.
1987: Lionel Henry Opie
Drug-related arrhythmias during therapy of congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1987;1(2):195-8.
1987: P I Pillans; Lionel Henry Opie
Antihypertensive therapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1987;71(11):736.
1987: W A Coetzee; S C Dennis; Lionel Henry Opie; C A Muller
Calcium channel blockers and early ischemic ventricular arrhythmias: electrophysiological versus anti-ischemic effects.
Journal of molecular and cellular cardiology 1987;19 Suppl 2():77-97.
1987: H G Eichler; T A Mabin; S Gasić; Lionel Henry Opie
Beta-blockade in acute myocardial infarction: is Swan-Ganz catheterization required before treatment?
International journal of clinical pharmacology, therapy, and toxicology 1987;25(4):204-7.
1987: C Vial; P Owen; Lionel Henry Opie; D Posel
Significance of release of adenosine triphosphate and adenosine induced by hypoxia or adrenaline in perfused rat heart.
Journal of molecular and cellular cardiology 1987;19(2):187-97.
1987: E van der Merwe; Ian Harper; P Owen; Amanda Lochner; S Wynchank; Lionel Henry Opie
Ultrastructural observations on the effects of different substrates on ischaemic contracture in global subtotal ischaemia in the rat heart.
Basic research in cardiology 1987;82 Suppl 2():285-7.
1987: Lionel Henry Opie
Practical therapy: adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs) in therapy of hypertension and congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1987;1(1):109-10.
1987: K Chatterjee; Lionel Henry Opie
Angiotensin inhibitors and other vasodilators with special reference to congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1987;1(1):1-8.
1987: Lionel Henry Opie
Angiotensin-converting enzyme inhibitors for cardiovascular therapy: recent advances at the Tenth World Congress of Cardiology Washington DC, September 14-19, 1986.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1987;1(1):111-2.
1987: A A Jennings; Lionel Henry Opie
Effects of intravenous ketanserin on severely hypertensive patients with double-blind crossover assessment of central side-effects.
Journal of cardiovascular pharmacology 1987;9(1):120-4.
1986: Lionel Henry Opie
Fluid retention with nifedipine in antihypertensive therapy.
Lancet 1986;2(8521-22):1456.
1986: Lionel Henry Opie; A A Jennings
Role of calcium channel blockade in chronic hypertension following successful management of hypertensive emergency.
The American journal of medicine 1986;81(6A):35-42.
1986: Lionel Henry Opie
Transdermal nitroglycerin.
American heart journal 1986;112(6):1345.
1986: M J Tansey; Lionel Henry Opie
Plasma glucose on admission to hospital as a metabolic index of the severity of acute myocardial infarction.
The Canadian journal of cardiology 1986;2(6):326-31.
1986: S S Maze; P J Commerford; Lionel Henry Opie
Lack of correlation between myocardial glycogen levels and perioperative change of left ventricular ejection fraction.
The Journal of thoracic and cardiovascular surgery 1986;92(4):804.
1986: C A Muller; Lionel Henry Opie; C W Hamm; M Peisach; D Gihwala
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
Journal of molecular and cellular cardiology 1986;18(4):375-87.
1985: Lionel Henry Opie; C A Muller; F T Thandroyen; E A Lloyd; T Mabin; P J Commerford; H G Eichler
Tiapamil--a new calcium antagonist.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1985;67(22):881-3.
1985: H G Eichler; T A Mabin; P J Commerford; E A Lloyd; W Beck; Lionel Henry Opie
Tiapamil, a new calcium antagonist: hemodynamic effects in patients with acute myocardial infarction.
Circulation 1985;71(4):779-86.
1984: G D Gordon; T A Mabin; S Isaacs; E A Lloyd; H G Eichler; Lionel Henry Opie
Hemodynamic effects of sublingual nifedipine in acute myocardial infarction.
The American journal of cardiology 1984;53(9):1228-32.
1983: Lionel Henry Opie; F T Thandroyen; C W Hamm; C A Muller; E A Lloyd; D Gordon
Calcium antagonists and the acutely ischemic heart: experimental effects on ventricular fibrillation and enzyme release.
European heart journal 1983;4 Suppl C():93-100.
1983: F T Thandroyen; M G Worthington; L M Higginson; Lionel Henry Opie
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
Journal of the American College of Cardiology 1983;1(4):1056-66.
1981: W F Lubbe; C A Muller; M Worthington; E L McFadyen; Lionel Henry Opie
Influence of propranolol isomers and atenolol on myocardial cyclic AMP, high energy phosphates and vulnerability to fibrillation after coronary artery ligation in the isolated rat heart.
Cardiovascular research 1981;15(12):690-9.
1981: F T Thandroyen; L M Higginson; Lionel Henry Opie
The interaction of calcium and cAMP and the relationship to ventricular vulnerability.
Basic research in cardiology 1981;76(4):449-52.