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Richard Cerione

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

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Amino Acid Sequence

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Protein Binding

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Mice
Cattle

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3T3 Cells

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Co-Publications
Name
13
Antonyak, Marc
12
Yang, Wannian
11
Bagrodia, Shubha
8
Feng, Qiyu
8
Hoffman, Gregory
7
Boehm, Jason
6
Baird, Daniel
6
Manor, D
5
Carraway, Kermit
5
Koland, John
5
Guan, Jun-Lin
4
Lin, Qiong
4
Nomanbhoy, TK
4
Wakshlag, Joseph
4
Wilson, Kristin

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Publications

TOP 3
Dias Sandra M G; Wilson Kristin F; Rojas Katherine S; Ambrosio Andre L B; Cerione Richard A
The molecular basis for the regulation of the cap-binding complex by the importins.
Johnson Jared L; Erickson Jon W; Cerione Richard A
New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes.
Antonyak Marc A; Cerione Richard A
Ras and the FAK paradox.

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All Publications

2009: Dias Sandra M G; Wilson Kristin F; Rojas Katherine S; Ambrosio Andre L B; Cerione Richard A
The molecular basis for the regulation of the cap-binding complex by the importins.
Nature structural & molecular biology 2009;16(9):930-7.
2009: Johnson Jared L; Erickson Jon W; Cerione Richard A
New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes.
The Journal of biological chemistry 2009;284(35):23860-71.
2009: Antonyak Marc A; Cerione Richard A
Ras and the FAK paradox.
Molecular cell 2009;35(2):141-2.
2009: Antonyak Marc A; Li Bo; Regan Andrew D; Feng Qiyu; Dusaban Stephanie S; Cerione Richard A
Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion.
The Journal of biological chemistry 2009;284(27):17914-25.
2009: Endo Makoto; Antonyak Marc A; Cerione Richard A
Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation.
The Journal of biological chemistry 2009;284(8):5107-18.
2008: Peng Xu; Wu Xiaoyang; Druso Joseph E; Wei Huijun; Park Ann Yong-Jin; Kraus Marc S; Alcaraz Ana; Chen Ju; Chien Shu; Cerione Richard A; Guan Jun-Lin
Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6638-43.
2008: Phillips Matthew J; Calero Guillermo; Chan Britton; Ramachandran Sekar; Cerione Richard A
Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42.
The Journal of biological chemistry 2008;283(20):14153-64.
2008: Erickson Jon W; Cerione Richard A
A new tool for G protein analysis.
ACS chemical biology 2008;3(1):24-6.
2008: DeRegis Carol J; Rahl Peter B; Hoffman Gregory R; Cerione Richard A; Collins Ruth N
Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function.
BMC cell biology 2008;9():3.
2007: Datta Sunando; Antonyak Marc A; Cerione Richard A
GTP-binding-defective forms of tissue transglutaminase trigger cell death.
Biochemistry 2007;46(51):14819-29.
2007: Dias Sandra M G; Cerione Richard A
X-ray crystal structures reveal two activated states for RhoC.
Biochemistry 2007;46(22):6547-58.
2007: Casey F P; Baird D; Feng Q; Gutenkunst R N; Waterfall J J; Myers C R; Brown K S; Cerione R A; Sethna J P
Optimal experimental design in an epidermal growth factor receptor signalling and down-regulation model.
IET systems biology 2007;1(3):190-202.
2006: Antonyak Marc A; Jansen Jaclyn M; Miller Allison M; Ly Thi K; Endo Makoto; Cerione Richard A
Two isoforms of tissue transglutaminase mediate opposing cellular fates.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18609-14.
2006: Datta Sunando; Antonyak Marc A; Cerione Richard A
Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis.
Biochemistry 2006;45(44):13163-74.
2006: Lin Qiong; Yang Wannian; Baird Daniel; Feng Qiyu; Cerione Richard A
Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42.
The Journal of biological chemistry 2006;281(46):35253-62.
2006: Ramachandran Sekar; Cerione Richard A
How GPCRs hit the switch.
Nature structural & molecular biology 2006;13(9):756-7.
2006: Feng Qiyu; Baird Dan; Peng Xu; Wang Jianbin; Ly Thi; Guan Jun-Lin; Cerione Richard A
Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth.
Nature cell biology 2006;8(9):945-56.
2006: Fidyk Nancy; Wang Jian-Bin; Cerione Richard A
Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42.
Biochemistry 2006;45(25):7750-62.
2006: Majumdar Sharmistha; Ramachandran Sekar; Cerione Richard A
New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins.
The Journal of biological chemistry 2006;281(14):9219-26.
2006: Wakshlag J J; McNeill C J; Antonyak M A; Boehm J E; Fuji R; Balkman C E; Zgola M; Cerione R A; Page R L
Expression and activity of transglutaminase II in spontaneous tumours of dogs and cats.
Journal of comparative pathology 2006;134(2-3):202-10.
2006: Wakshlag Joseph J; Antonyak Marc A; Boehm Jason E; Boehm Karen; Cerione Richard A
Effects of tissue transglutaminase on beta -amyloid1-42-induced apoptosis.
The protein journal 2006;25(1):83-94.
2006: Lin Qiong; Yang Wannian; Cerione Richard A
Measurement of epidermal growth factor receptor turnover and effects of Cdc42.
Methods in enzymology 2006;406():614-25.
2006: Baird Daniel; Feng Qiyu; Cerione Richard A
Biochemical characterization of the Cool (Cloned-out-of-Library)/Pix (Pak-interactive exchange factor) proteins.
Methods in enzymology 2006;406():58-69.
2005: Smith William J; Hamel Brant; Yohe Marielle E; Sondek John; Cerione Richard A; Snyder Jason T
A Cdc42 mutant specifically activated by intersectin.
Biochemistry 2005;44(40):13282-90.
2005: Pereira Ryan; Cerione Richard A
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
The Journal of biological chemistry 2005;280(42):35696-703.
2005: Wang Jian-Bin; Wu Wen Jin; Cerione Richard A
Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.
The Journal of biological chemistry 2005;280(24):22883-91.
2005: Baird Dan; Feng Qiyu; Cerione Richard A
The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.
Current biology : CB 2005;15(1):1-10.
2004: Brown K S; Hill C C; Calero G A; Myers C R; Lee K H; Sethna J P; Cerione R A
The statistical mechanics of complex signaling networks: nerve growth factor signaling.
Physical biology 2004;1(3-4):184-95.
2004: Antonyak Marc A; Miller Allison M; Jansen Jaclyn M; Boehm Jason E; Balkman Cheryl E; Wakshlag Joseph J; Page Rodney L; Cerione Richard A
Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells.
The Journal of biological chemistry 2004;279(40):41461-7.
2004: Feng Qiyu; Baird Daniel; Cerione Richard A
Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix.
The EMBO journal 2004;23(17):3492-504.
2004: Majumdar Sharmistha; Ramachandran Sekar; Cerione Richard A
Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins.
The Journal of biological chemistry 2004;279(38):40137-45.
2004: Yang Wannian; Jansen Jaclyn M; Lin Qiong; Canova Sabrina; Cerione Richard A; Childress Chandra
Interaction of activated Cdc42-associated tyrosine kinase ACK2 with HSP90.
The Biochemical journal 2004;382(Pt 1):199-204.
2004: Ramachandran Sekar; Cerione Richard A
Stabilization of an intermediate activation state for transducin by a fluorescent GTP analogue.
Biochemistry 2004;43(27):8778-86.
2004: Fortier Lisa A; Deak Molly M; Semevolos Stacy A; Cerione Richard A
Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(2):436-45.
2004: Cerione Richard A
Cdc42: new roads to travel.
Trends in cell biology 2004;14(3):127-32.
2004: Erickson Jon W; Cerione Richard A
Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes.
Biochemistry 2004;43(4):837-42.
2003: Tu Shine; Wu Wen Jin; Wang Jiabin; Cerione Richard A
Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase.
The Journal of biological chemistry 2003;278(49):49293-300.
2003: Hoffman Gregory R; Rahl Peter B; Collins Ruth N; Cerione Richard A
Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain.
Molecular cell 2003;12(3):615-25.
2003: Wu Wen Jin; Tu Shine; Cerione Richard A
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation.
Cell 2003;114(6):715-25.
2003: Lin Qiong; Fuji Reina N; Yang Wannian; Cerione Richard A
RhoGDI is required for Cdc42-mediated cellular transformation.
Current biology : CB 2003;13(17):1469-79.
2003: Flanders James A; Feng Qiyu; Bagrodia Shubha; Laux Maria T; Singavarapu Avinash; Cerione Richard A
The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins.
FEBS letters 2003;550(1-3):119-23.
2003: Antonyak Marc A; McNeill Conor J; Wakshlag Joseph J; Boehm Jason E; Cerione Richard A
Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells.
The Journal of biological chemistry 2003;278(18):15859-66.
2003: Smith William James; Nassar Nicolas; Bretscher Anthony; Cerione Richard A; Karplus P Andrew
Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions.
The Journal of biological chemistry 2003;278(7):4949-56.
2002: Fidyk Nancy J; Cerione Richard A
Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis.
Biochemistry 2002;41(52):15644-53.
2002: Calero Guillermo; Wilson Kristin F; Ly Thi; Rios-Steiner Jorge L; Clardy Jon C; Cerione Richard A
Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nature structural biology 2002;9(12):912-7.
2002: Osman Mahasin A; Konopka James B; Cerione Richard A
Iqg1p links spatial and secretion landmarks to polarity and cytokinesis.
The Journal of cell biology 2002;159(4):601-11.
2002: Tu Shine S; Wu Wen Jin; Yang Wannian; Nolbant Peri; Hahn Klaus; Cerione Richard A
Antiapoptotic Cdc42 mutants are potent activators of cellular transformation.
Biochemistry 2002;41(41):12350-8.
2002: Smith William J; Cerione Richard A
Crystallization and preliminary crystallographic analysis of the ezrin FERM domain.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 8):1359-61.
2002: Daniel Samira; Noda Mitsuhiko; Cerione Richard A; Sharp Geoffrey W G
A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release.
Biochemistry 2002;41(30):9663-71.
2002: Boehm Jason E; Singh Ugra; Combs Carolyn; Antonyak Marc A; Cerione Richard A
Tissue transglutaminase protects against apoptosis by modifying the tumor suppressor protein p110 Rb.
The Journal of biological chemistry 2002;277(23):20127-30.
2002: Antonyak Marc A; Boehm Jason E; Cerione Richard A
Phosphoinositide 3-kinase activity is required for retinoic acid-induced expression and activation of the tissue transglutaminase.
The Journal of biological chemistry 2002;277(17):14712-6.
2002: Liu Shenping; Cerione Richard A; Clardy Jon
Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2743-7.
2002: Lin Qiong; Lo Charles G; Cerione Richard A; Yang Wannian
The Cdc42 target ACK2 interacts with sorting nexin 9 (SH3PX1) to regulate epidermal growth factor receptor degradation.
The Journal of biological chemistry 2002;277(12):10134-8.
2002: Hoffman Gregory R; Cerione Richard A
Signaling to the Rho GTPases: networking with the DH domain.
FEBS letters 2002;513(1):85-91.
2002: Feng Qiyu; Albeck John G; Cerione Richard A; Yang Wannian
Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.
The Journal of biological chemistry 2002;277(7):5644-50.
2001: Yang W; Lin Q; Zhao J; Guan J L; Cerione R A
The nonreceptor tyrosine kinase ACK2, a specific target for Cdc42 and a negative regulator of cell growth and focal adhesion complexes.
The Journal of biological chemistry 2001;276(47):43987-93.
2001: Antonyak M A; Singh U S; Lee D A; Boehm J E; Combs C; Zgola M M; Page R L; Cerione R A
Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis.
The Journal of biological chemistry 2001;276(36):33582-7.
2001: Tu S; Cerione R A
Cdc42 is a substrate for caspases and influences Fas-induced apoptosis.
The Journal of biological chemistry 2001;276(22):19656-63.
2001: Yang W; Lo C G; Dispenza T; Cerione R A
The Cdc42 target ACK2 directly interacts with clathrin and influences clathrin assembly.
The Journal of biological chemistry 2001;276(20):17468-73.
2001: Erickson J W; Cerione R A
Multiple roles for Cdc42 in cell regulation.
Current opinion in cell biology 2001;13(2):153-7.
2001: Hoffman G R; Cerione R A
Rac inserts its way into the immune response.
Nature immunology 2001;2(3):194-6.
2001: Hong-Geller E; Holowka D; Siraganian R P; Baird B; Cerione R A
Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1154-9.
2000: Wilson K F; Wu W J; Cerione R A
Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex.
The Journal of biological chemistry 2000;275(48):37307-10.
2000: Hoffman G R; Cerione R A
Flipping the switch: the structural basis for signaling through the CRIB motif.
Cell 2000;102(4):403-6.
2000: Wilson K F; Cerione R A
Signal transduction and post-transcriptional gene expression.
Biological chemistry 2000;381(5-6):357-65.
2000: Walker S J; Wu W J; Cerione R A; Brown H A
Activation of phospholipase D1 by Cdc42 requires the Rho insert region.
The Journal of biological chemistry 2000;275(21):15665-8.
2000: Hoffman G R; Nassar N; Cerione R A
Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell 2000;100(3):345-56.
2000: Hong-Geller E; Cerione R A
Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells.
The Journal of cell biology 2000;148(3):481-94.
1999: Nomanbhoy T; Cerione R A
Fluorescence assays of Cdc42 interactions with target/effector proteins.
Biochemistry 1999;38(48):15878-84.
1999: Bagrodia S; Cerione R A
Pak to the future.
Trends in cell biology 1999;9(9):350-5.
1999: Lin R; Cerione R A; Manor D
Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation.
The Journal of biological chemistry 1999;274(33):23633-41.
1999: Bagrodia S; Bailey D; Lenard Z; Hart M; Guan J L; Premont R T; Taylor S J; Cerione R A
A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.
The Journal of biological chemistry 1999;274(32):22393-400.
1999: Yang W; Cerione R A
Endocytosis: Is dynamin a 'blue collar' or 'white collar' worker?
Current biology : CB 1999;9(14):R511-4.
1999: Chen L M; Bagrodia S; Cerione R A; Galán J E
Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses.
The Journal of experimental medicine 1999;189(9):1479-88.
1999: Yang W; Lin Q; Guan J L; Cerione R A
Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1.
The Journal of biological chemistry 1999;274(13):8524-30.
1999: Nomanbhoy T K; Erickson J W; Cerione R A
Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer.
Biochemistry 1999;38(6):1744-50.
1999: Wilson K F; Fortes P; Singh U S; Ohno M; Mattaj I W; Cerione R A
The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction.
The Journal of biological chemistry 1999;274(7):4166-73.
1999: Berger A L; Cerione R A; Erickson J W
Delineation of two functionally distinct gammaPDE binding sites on the bovine retinal cGMP phosphodiesterase by a mutant gammaPDE subunit.
Biochemistry 1999;38(4):1293-9.
1999: Glaven J A; Whitehead I; Bagrodia S; Kay R; Cerione R A
The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells.
The Journal of biological chemistry 1999;274(4):2279-85.
1998: Nassar N; Hoffman G R; Manor D; Clardy J C; Cerione R A
Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nature structural biology 1998;5(12):1047-52.
1998: Guo W; Sutcliffe M J; Cerione R A; Oswald R E
Identification of the binding surface on Cdc42Hs for p21-activated kinase.
Biochemistry 1998;37(40):14030-7.
1998: Bagrodia S; Taylor S J; Jordon K A; Van Aelst L; Cerione R A
A novel regulator of p21-activated kinases.
The Journal of biological chemistry 1998;273(37):23633-6.
1998: McCallum S J; Erickson J W; Cerione R A
Characterization of the association of the actin-binding protein, IQGAP, and activated Cdc42 with Golgi membranes.
The Journal of biological chemistry 1998;273(35):22537-44.
1998: Osman M A; Cerione R A
Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton.
The Journal of cell biology 1998;142(2):443-55.
1998: Wu W J; Lin R; Cerione R A; Manor D
Transformation activity of Cdc42 requires a region unique to Rho-related proteins.
The Journal of biological chemistry 1998;273(27):16655-8.
1998: Leonard D A; Lin R; Cerione R A; Manor D
Biochemical studies of the mechanism of action of the Cdc42-GTPase-activating protein.
The Journal of biological chemistry 1998;273(26):16210-5.
1998: Hoffman G R; Nassar N; Oswald R E; Cerione R A
Fluoride activation of the Rho family GTP-binding protein Cdc42Hs.
The Journal of biological chemistry 1998;273(8):4392-9.
1998: Singh U S; Li Q; Cerione R
Identification of the eukaryotic initiation factor 5A as a retinoic acid-stimulated cellular binding partner for tissue transglutaminase II.
The Journal of biological chemistry 1998;273(4):1946-50.
1998: Nomanbhoy T; Cerione R A
Use of fluorescence spectroscopy to study the regulation of small G proteins.
Methods in molecular biology (Clifton, N.J.) 1998;84():237-47.
1997: Lin R; Bagrodia S; Cerione R; Manor D
A novel Cdc42Hs mutant induces cellular transformation.
Current biology : CB 1997;7(10):794-7.
1997: Yang W; Cerione R A
Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain.
The Journal of biological chemistry 1997;272(40):24819-24.
1997: Erickson J W; Cerione R A; Hart M J
Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase.
The Journal of biological chemistry 1997;272(39):24443-7.
1997: Li Q; Cerione R A
Communication between switch II and switch III of the transducin alpha subunit is essential for target activation.
The Journal of biological chemistry 1997;272(35):21673-6.
1997: Feltham J L; Dötsch V; Raza S; Manor D; Cerione R A; Sutcliffe M J; Wagner G; Oswald R E
Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry 1997;36(29):8755-66.
1997: Gosser Y Q; Nomanbhoy T K; Aghazadeh B; Manor D; Combs C; Cerione R A; Rosen M K
C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature 1997;387(6635):814-9.
1997: Gamett D C; Pearson G; Cerione R A; Friedberg I
Secondary dimerization between members of the epidermal growth factor receptor family.
The Journal of biological chemistry 1997;272(18):12052-6.
1997: Leonard D A; Satoskar R S; Wu W J; Bagrodia S; Cerione R A; Manor D
Use of a fluorescence spectroscopic readout to characterize the interactions of Cdc42Hs with its target/effector, mPAK-3.
Biochemistry 1997;36(5):1173-80.
1997: Berger A L; Cerione R A; Erickson J W
Real time conformational changes in the retinal phosphodiesterase gamma subunit monitored by resonance energy transfer.
The Journal of biological chemistry 1997;272(5):2714-21.
1996: Glaven J A; Whitehead I P; Nomanbhoy T; Kay R; Cerione R A
Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein.
The Journal of biological chemistry 1996;271(44):27374-81.
1996: Singh U S; Cerione R A
Biochemical effects of retinoic acid on GTP-binding Protein/Transglutaminases in HeLa cells. Stimulation of GTP-binding and transglutaminase activity, membrane association, and phosphatidylinositol lipid turnover.
The Journal of biological chemistry 1996;271(44):27292-8.
1996: Erickson J W; Zhang C j; Kahn R A; Evans T; Cerione R A
Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus.
The Journal of biological chemistry 1996;271(43):26850-4.
1996: Zheng Y; Glaven J A; Wu W J; Cerione R A
Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs.
The Journal of biological chemistry 1996;271(39):23815-9.
1996: Zheng Y; Zangrilli D; Cerione R A; Eva A
The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting.
The Journal of biological chemistry 1996;271(32):19017-20.
1996: Cerione R A; Zheng Y
The Dbl family of oncogenes.
Current opinion in cell biology 1996;8(2):216-22.
1996: Nomanbhoy T K; Cerione R
Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy.
The Journal of biological chemistry 1996;271(17):10004-9.
1996: Nomanbhoy T K; Leonard D A; Manor D; Cerione R A
Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence.
Biochemistry 1996;35(14):4602-8.
1996: Mittal R; Erickson J W; Cerione R A
Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.
Science (New York, N.Y.) 1996;271(5254):1413-6.
1995: Singh U S; Erickson J W; Cerione R A
Identification and biochemical characterization of an 80 kilodalton GTP-binding/transglutaminase from rabbit liver nuclei.
Biochemistry 1995;34(48):15863-71.
1995: Bagrodia S; Dérijard B; Davis R J; Cerione R A
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation.
The Journal of biological chemistry 1995;270(47):27995-8.
1995: Bagrodia S; Taylor S J; Creasy C L; Chernoff J; Cerione R A
Identification of a mouse p21Cdc42/Rac activated kinase.
The Journal of biological chemistry 1995;270(39):22731-7.
1995: Gamett D C; Greene T; Wagreich A R; Kim H H; Koland J G; Cerione R A
Heregulin-stimulated signaling in rat pheochromocytoma cells. Evidence for ErbB3 interactions with Neu/ErbB2 and p85.
The Journal of biological chemistry 1995;270(32):19022-7.
1995: Erickson J W; Mittal R; Cerione R A
Use of resonance energy transfer to determine the proximity of the guanine nucleotide binding site of transducin relative to a conformationally-sensitive site on the gamma subunit of the cyclic GMP phosphodiesterase.
Biochemistry 1995;34(27):8693-700.
1995: Zheng Y; Olson M F; Hall A; Cerione R A; Toksoz D
Direct involvement of the small GTP-binding protein Rho in lbc oncogene function.
The Journal of biological chemistry 1995;270(16):9031-4.
1995: Platko J V; Leonard D A; Adra C N; Shaw R J; Cerione R A; Lim B
A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2974-8.
1995: Zheng Y; Bender A; Cerione R A
Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae.
The Journal of biological chemistry 1995;270(2):626-30.
1995: Leonard D A; Cerione R A
Solubilization of Cdc42Hs from membranes by Rho-GDP dissociation inhibitor.
Methods in enzymology 1995;256():98-105.
1995: Zheng Y; Hart M J; Cerione R A
Guanine nucleotide exchange catalyzed by dbl oncogene product.
Methods in enzymology 1995;256():77-84.
1995: Cerione R A; Leonard D; Zheng Y
Purification of baculovirus-expressed Cdc42Hs.
Methods in enzymology 1995;256():11-5.
1994: Peterson J; Zheng Y; Bender L; Myers A; Cerione R; Bender A
Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.
The Journal of cell biology 1994;127(5):1395-406.
1994: Leonard D A; Evans T; Hart M; Cerione R A; Manor D
Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy.
Biochemistry 1994;33(40):12323-8.
1994: Gamett D C; Cerione R A
Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells.
FEBS letters 1994;351(3):335-9.
1994: Guy P M; Platko J V; Cantley L C; Cerione R A; Carraway K L
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8132-6.
1994: Mittal R; Cerione R A; Erickson J W
Aluminum fluoride activation of bovine transducin induces two distinct conformational changes in the alpha subunit.
Biochemistry 1994;33(33):10178-84.
1994: Zheng Y; Bagrodia S; Cerione R A
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.
The Journal of biological chemistry 1994;269(29):18727-30.
1994: Carraway K L; Sliwkowski M X; Akita R; Platko J V; Guy P M; Nuijens A; Diamonti A J; Vandlen R L; Cantley L C; Cerione R A
The erbB3 gene product is a receptor for heregulin.
The Journal of biological chemistry 1994;269(19):14303-6.
1994: Sliwkowski M X; Schaefer G; Akita R W; Lofgren J A; Fitzpatrick V D; Nuijens A; Fendly B M; Cerione R A; Vandlen R L; Carraway K L
Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.
The Journal of biological chemistry 1994;269(20):14661-5.
1994: Phillips W J; Cerione R A
A C-terminal peptide of bovine rhodopsin binds to the transducin alpha-subunit and facilitates its activation.
The Biochemical journal 1994;299 ( Pt 2)():351-7.
1994: Zheng Y; Cerione R; Bender A
Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.
The Journal of biological chemistry 1994;269(4):2369-72.
1994: Hart M J; Eva A; Zangrilli D; Aaronson S A; Evans T; Cerione R A; Zheng Y
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product.
The Journal of biological chemistry 1994;269(1):62-5.
1994: Cerione R A
Fluorescence assays for G-protein interactions.
Methods in enzymology 1994;237():409-23.
1993: Adra C N; Ko J; Leonard D; Wirth L J; Cerione R A; Lim B
Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I.
Genes, chromosomes & cancer 1993;8(4):253-61.
1993: Zheng Y; Hart M J; Shinjo K; Evans T; Bender A; Cerione R A
Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.
The Journal of biological chemistry 1993;268(33):24629-34.
1993: Carraway K L; Cerione R A
Inhibition of epidermal growth factor receptor aggregation by an antibody directed against the epidermal growth factor receptor extracellular domain.
The Journal of biological chemistry 1993;268(32):23860-7.
1993: Erickson J W; Cerione R A
Regulation of the cGMP phosphodiesterase in bovine rod outer segments. Use of resonance energy transfer to distinguish between associative and dissociative activation mechanisms.
The Journal of biological chemistry 1993;268(5):3328-33.
1992: Leonard D; Hart M J; Platko J V; Eva A; Henzel W; Evans T; Cerione R A
The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein.
The Journal of biological chemistry 1992;267(32):22860-8.
1992: Hart M J; Maru Y; Leonard D; Witte O N; Evans T; Cerione R A
A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs.
Science (New York, N.Y.) 1992;258(5083):812-5.
1992: Phillips W J; Wong S C; Cerione R A
Rhodopsin/transducin interactions. II. Influence of the transducin-beta gamma subunit complex on the coupling of the transducin-alpha subunit to rhodopsin.
The Journal of biological chemistry 1992;267(24):17040-6.
1992: Phillips W J; Cerione R A
Rhodopsin/transducin interactions. I. Characterization of the binding of the transducin-beta gamma subunit complex to rhodopsin using fluorescence spectroscopy.
The Journal of biological chemistry 1992;267(24):17032-9.
1992: Narasimhan V; Hamill O; Cerione R A
The effects of the normal and oncogenic forms of the neu tyrosine kinase, and the corresponding forms of an immunoglobulin E receptor/neu tyrosine kinase fusion protein, on Xenopus oocyte maturation.
FEBS letters 1992;303(2-3):164-8.
1991: Cerione R A
Reconstitution of receptor/GTP-binding protein interactions.
Biochimica et biophysica acta 1991;1071(4):473-501.
1991: Hart M J; Eva A; Evans T; Aaronson S A; Cerione R A
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product.
Nature 1991;354(6351):311-4.
1991: Hart M J; Shinjo K; Hall A; Evans T; Cerione R A
Identification of the human platelet GTPase activating protein for the CDC42Hs protein.
The Journal of biological chemistry 1991;266(31):20840-8.
1991: Erickson J W; Cerione R A
Resonance energy transfer as a direct monitor of GTP-binding protein-effector interactions: activated alpha-transducin binding to the cGMP phosphodiesterase in the bovine phototransduction cascade.
Biochemistry 1991;30(29):7112-8.
1991: Phillips W J; Cerione R A
Labeling of the beta gamma subunit complex of transducin with an environmentally sensitive cysteine reagent. Use of fluorescence spectroscopy to monitor transducin subunit interactions.
The Journal of biological chemistry 1991;266(17):11017-24.
1990: Shinjo K; Koland J G; Hart M J; Narasimhan V; Johnson D I; Evans T; Cerione R A
Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9853-7.
1990: Carraway K L; Koland J G; Cerione R A
Location of the epidermal growth factor binding site on the EGF receptor. A resonance energy transfer study.
Biochemistry 1990;29(37):8741-7.
1990: Koland J G; Cerione R A
Activation of the EGF receptor tyrosine kinase by divalent metal ions: comparison of holoreceptor and isolated kinase domain properties.
Biochimica et biophysica acta 1990;1052(3):489-98.
1990: Koland J G; O'Brien K M; Cerione R A
Expression of epidermal growth factor receptor sequences as E. coli fusion proteins: applications in the study of tyrosine kinase function.
Biochemical and biophysical research communications 1990;166(1):90-100.
1989: Phillips W J; Trukawinski S; Cerione R A
An antibody-induced enhancement of the transducin-stimulated cyclic GMP phosphodiesterase activity.
The Journal of biological chemistry 1989;264(28):16679-88.
1989: Kroll S; Phillips W J; Cerione R A
The regulation of the cyclic GMP phosphodiesterase by the GDP-bound form of the alpha subunit of transducin.
The Journal of biological chemistry 1989;264(8):4490-7.
1988: Phillips W J; Cerione R A
The intrinsic fluorescence of the alpha subunit of transducin. Measurement of receptor-dependent guanine nucleotide exchange.
The Journal of biological chemistry 1988;263(30):15498-505.
1988: Krupinski J; Rajaram R; Lakonishok M; Benovic J L; Cerione R A
Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles.
The Journal of biological chemistry 1988;263(25):12333-41.
1988: Cerione R A; Kroll S; Rajaram R; Unson C; Goldsmith P; Spiegel A M
An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function.
The Journal of biological chemistry 1988;263(19):9345-52.
1988: Horne W A; Abdel-Ghany M; Racker E; Weiland G A; Oswald R E; Cerione R A
Functional reconstitution of skeletal muscle Ca2+ channels: separation of regulatory and channel components.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3718-22.
1988: Koland J G; Cerione R A
Growth factor control of epidermal growth factor receptor kinase activity via an intramolecular mechanism.
The Journal of biological chemistry 1988;263(5):2230-7.
1986: Horne W A; Weiland G A; Oswald R E; Cerione R A
Rapid incorporation of the solubilized dihydropyridine receptor into phospholipid vesicles.
Biochimica et biophysica acta 1986;863(2):205-12.

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