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Jean-Charles Cerottini

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Anatomy

Chemicals & Drugs

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Melanoma

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Gabriel Bricard; Valerie Cesson; Estelle Devevre; Hanifa Bouzourene; Catherine Barbey; Nathalie Rufer; Jin S Im; Pedro M S Alves; Olivier Martinet; Nermin Halkic; Jean-Charles Cerottini; Pedro Romero; Steven A Porcelli; H Robson MacDonald; Daniel E Speiser
Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors.
Jean-Charles Cerottini; Pedro Romero
Lipid A in cancer therapy. Foreword.
Pedro M S Alves; Sebastien Viatte; Theres Fagerberg; Olivier Michielin; Gabriel Bricard; Hanifa Bouzourene; Henri Vuilleumier; Thorsten Kruger; Jean-Claude Givel; Frédéric Lévy; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients.

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2009: Gabriel Bricard; Valerie Cesson; Estelle Devevre; Hanifa Bouzourene; Catherine Barbey; Nathalie Rufer; Jin S Im; Pedro M S Alves; Olivier Martinet; Nermin Halkic; Jean-Charles Cerottini; Pedro Romero; Steven A Porcelli; H Robson MacDonald; Daniel E Speiser
Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5140-51.
2009: Jean-Charles Cerottini; Pedro Romero
Lipid A in cancer therapy. Foreword.
Advances in experimental medicine and biology 2009;667():v-vi.
2007: Pedro M S Alves; Sebastien Viatte; Theres Fagerberg; Olivier Michielin; Gabriel Bricard; Hanifa Bouzourene; Henri Vuilleumier; Thorsten Kruger; Jean-Claude Givel; Frédéric Lévy; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients.
Cancer immunology, immunotherapy : CII 2007;56(11):1795-805.
2007: Catherine Barbey; Petra Baumgaertner; Estelle Devevre; Verena Rubio-Godoy; Laurent Derré; Gabriel Bricard; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer; Daniel E Speiser
IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3566-74.
2007: Victor Appay; Verena Voelter; Nathalie Rufer; Severine Reynard; Camilla Jandus; Danielle Gasparini; Danielle Lienard; Daniel E Speiser; Philippe Schneider; Jean-Charles Cerottini; Pedro Romero; Serge Leyvraz
Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(2):240-50.
2006: Julie Tabiasco; Estelle Devêvre; Nathalie Rufer; Bruno Salaun; Jean-Charles Cerottini; Daniel Speiser; Pedro Romero
Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8708-13.
2006: Gilles Bioley; Camilla Jandus; Sandra Tuyaerts; Donata Rimoldi; William W Kwok; Daniel E Speiser; Jean-Marie Tiercy; Kris Thielemans; Jean-Charles Cerottini; Pedro Romero
Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6769-79.
2006: Victor Appay; Camilla Jandus; Verena Voelter; Severine Reynard; Sarah E Coupland; Donata Rimoldi; Danielle Lienard; Philippe Guillaume; Arthur M Krieg; Jean-Charles Cerottini; Pedro Romero; Serge Leyvraz; Nathalie Rufer; Daniel E Speiser
New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1670-8.
2006: Daniel E Speiser; Petra Baumgaertner; Catherine Barbey; Verena Rubio-Godoy; Alexandre Moulin; Patricia Corthesy; Estelle Devevre; Pierre-Yves Dietrich; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer
A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1338-48.
2006: Victor Appay; Daniel E Speiser; Nathalie Rufer; Severine Reynard; Catherine Barbey; Jean-Charles Cerottini; Serge Leyvraz; Clemencia Pinilla; Pedro Romero
Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide.
European journal of immunology 2006;36(7):1805-14.
2006: Pascal Batard; Daniel A Peterson; Estelle Devêvre; Philippe Guillaume; Jean-Charles Cerottini; Donata Rimoldi; Daniel E Speiser; Lars Winther; Pedro Romero
Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells.
Journal of immunological methods 2006;310(1-2):136-48.
2006: Theres Fagerberg; Jean-Charles Cerottini; Olivier Michielin
Structural prediction of peptides bound to MHC class I.
Journal of molecular biology 2006;356(2):521-46.
2006: Mikaël J Pittet; Asma Gati; Frédérique-Anne Le Gal; Gilles Bioley; Philippe Guillaume; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Alfred Zippelius
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2330-6.
2006: Laurence Chapatte; Sara Colombetti; Jean-Charles Cerottini; Frédéric Lévy
Efficient induction of tumor antigen-specific CD8+ memory T cells by recombinant lentivectors.
Cancer research 2006;66(2):1155-60.
2006: Pedro Romero; Jean-Charles Cerottini; Daniel E Speiser
The human T cell response to melanoma antigens.
Advances in immunology 2006;92():187-224.
2005: Pedro Romero; Jean-Charles Cerottini; Immanuel F Luescher
On the significance of CD8 alpha alpha expression for T cell memory.
European journal of immunology 2005;35(11):3092-4.
2005: M Montes; Nathalie Rufer; Victor Appay; Severine Reynard; Mikaël J Pittet; D E Speiser; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; S Leyvraz
Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy.
Clinical and experimental immunology 2005;142(2):292-302.
2005: Frédérique-Anne Le Gal; Maha Ayyoub; Valérie Dutoit; Valérie Widmer; Elke Jäger; Jean-Charles Cerottini; Pierre-Yves Dietrich; Danila Valmori
Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(3):252-7.
2005: Maha Ayyoub; Andrea Merlo; Charles Hesdorffer; Donata Rimoldi; Daniel Speiser; Jean-Charles Cerottini; Yao-Tseng Chen; Lloyd J Old; Stefan Stevanovic; Danila Valmori
CD4+ T cell responses to SSX-4 in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):5092-9.
2005: Frédéric Lévy; Katja Muehlethaler; Suzanne Salvi; Anne-Lise Peitrequin; Cecilia K Lindholm; Jean-Charles Cerottini; Donata Rimoldi
Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradation.
Molecular biology of the cell 2005;16(4):1777-87.
2005: Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Tumor cell recognition efficiency by T cells.
PLoS medicine 2005;2(3):e77; author reply e95.
2005: Daniel E Speiser; Danielle Liénard; Nathalie Rufer; Verena Rubio-Godoy; Donata Rimoldi; Ferdy Lejeune; Arthur M Krieg; Jean-Charles Cerottini; Pedro Romero
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.
The Journal of clinical investigation 2005;115(3):739-46.
2005: Gabriel Bricard; Hanifa Bouzourene; Olivier Martinet; Donata Rimoldi; Nermin Halkic; Michel Gillet; Pascal Chaubert; H Robson MacDonald; Pedro Romero; Jean-Charles Cerottini; Daniel E Speiser
Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1709-16.
2005: Yolanda D Mahnke; Daniel Speiser; Immanuel F Luescher; Jean-Charles Cerottini; Pedro Romero
Recent advances in tumour antigen-specific therapy: in vivo veritas.
International journal of cancer. Journal international du cancer 2005;113(2):173-8.
2005: Olivier Michielin; Jean-Sebastien Blanchet; Theres Fagerberg; Danila Valmori; Verena Rubio-Godoy; Daniel Speiser; Maha Ayyoub; Pedro Alves; Immanuel F Luescher; Jean Edouard Gairin; Jean-Charles Cerottini; Pedro Romero
Tinkering with nature: the tale of optimizing peptide based cancer vaccines.
Cancer treatment and research 2005;123():267-91.
2005: Maha Ayyoub; Andrea Merlo; Charles Hesdorffer; Daniel Speiser; Donata Rimoldi; Jean-Charles Cerottini; Gerd Ritter; Yao-Tseng Chen; Lloyd J Old; Stefan Stevanovic; Danila Valmori
Distinct but overlapping T helper epitopes in the 37-58 region of SSX-2.
Clinical immunology (Orlando, Fla.) 2005;114(1):70-8.
2004: Daniel E Speiser; Mikaël J Pittet; Philippe Guillaume; Norbert Lubenow; Eric Hoffman; Jean-Charles Cerottini; Pedro Romero
Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):298-308.
2004: Maha Ayyoub; Charles Hesdorffer; Genevieve Metthez; Stefan Stevanovic; Gerd Ritter; Yao-Tseng Chen; Lloyd J Old; Daniel Speiser; Jean-Charles Cerottini; Danila Valmori
Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7206-11.
2004: Danielle Liénard; Donata Rimoldi; Marie Marchand; Pierre-Yves Dietrich; Nicolas van Baren; Christine Geldhof; Pascal Batard; Philippe Guillaume; Maha Ayyoub; Mikaël J Pittet; Alfred Zippelius; Katharina Fleischhauer; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer immunity 2004;4():4.
2004: Alfred Zippelius; Pascal Batard; Verena Rubio-Godoy; Gilles Bioley; Danielle Liénard; Ferdy Lejeune; Donata Rimoldi; Philippe Guillaume; Norbert Meidenbauer; Andreas Mackensen; Nathalie Rufer; Norbert Lubenow; Daniel Speiser; Jean-Charles Cerottini; Pedro Romero; Mikaël J Pittet
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.
Cancer research 2004;64(8):2865-73.
2004: Maha Ayyoub; Charles Hesdorffer; Monica Montes; Andrea Merlo; Daniel Speiser; Donata Rimoldi; Jean-Charles Cerottini; Gerd Ritter; Matthew Scanlan; Lloyd J Old; Danila Valmori
An immunodominant SSX-2-derived epitope recognized by CD4+ T cells in association with HLA-DR.
The Journal of clinical investigation 2004;113(8):1225-33.
2004: Alfred Zippelius; Gilles Bioley; Frédérique-Anne Le Gal; Nathalie Rufer; Marlene Brandes; Pascal Batard; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Mikaël J Pittet
Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2773-7.
2004: Pedro Romero; Jean-Charles Cerottini; Daniel E Speiser
Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination.
Cancer immunology, immunotherapy : CII 2004;53(3):249-55.
2003: Daniel E Speiser; Mikaël J Pittet; Donata Rimoldi; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Seminars in cancer biology 2003;13(6):461-72.
2003: Danila Valmori; Valérie Dutoit; Maha Ayyoub; Donata Rimoldi; Philippe Guillaume; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.
Cancer immunity 2003;3():15.
2003: Donata Rimoldi; Suzanne Salvi; Danielle Liénard; Ferdy J Lejeune; Daniel Speiser; Leonidas Zografos; Jean-Charles Cerottini
Lack of BRAF mutations in uveal melanoma.
Cancer research 2003;63(18):5712-5.
2003: Daniel E Speiser; Donata Rimoldi; Pascal Batard; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Disease-driven T cell activation predicts immune responses to vaccination against melanoma.
Cancer immunity 2003;3():12.
2003: Maha Ayyoub; Donata Rimoldi; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Danila Valmori; Daniel Speiser
Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients.
Cancer research 2003;63(17):5601-6.
2003: Nathalie Rufer; Alfred Zippelius; Pascal Batard; Mikaël J Pittet; Isabel Kurth; Patricia Corthesy; Jean-Charles Cerottini; Serge Leyvraz; Eddy Roosnek; Markus Nabholz; Pedro Romero
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.
Blood 2003;102(5):1779-87.
2003: Mikaël J Pittet; Verena Rubio-Godoy; Gilles Bioley; Philippe Guillaume; Pascal Batard; Daniel Speiser; Immanuel F Luescher; Jean-Charles Cerottini; Pedro Romero; Alfred Zippelius
Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1844-9.
2003: Pierre-Yves Dietrich; Frédérique-Anne Le Gal; Valérie Dutoit; Mikaël J Pittet; Lydie Trautman; Alfred Zippelius; Isabelle Cognet; Valérie Widmer; Paul R Walker; Olivier Michielin; Philippe Guillaume; Thierry Connerotte; Francine Jotereau; Pierre G Coulie; Pedro Romero; Jean-Charles Cerottini; Marc Bonneville; Danila Valmori
Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5103-9.
2003: Philippe Guillaume; Daniel F Legler; Nicole Boucheron; Marie-Agnès Doucey; Jean-Charles Cerottini; Immanuel F Luescher
Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis.
The Journal of biological chemistry 2003;278(7):4500-9.
2003: Maha Ayyoub; Alfred Zippelius; Mikaël J Pittet; Donata Rimoldi; Danila Valmori; Jean-Charles Cerottini; Pedro Romero; Ferdy Lejeune; Danielle Liénard; Daniel E Speiser
Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):669-77.
2002: Pedro Romero; Mikael Pittet; Valérie Dutoit; Alfred Zippelius; Danielle Liénard; Ferdy Lejeune; Philippe Guillaume; Donata Rimoldi; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini
Therapeutic cancer vaccines based on molecularly defined human tumor antigens.
Vaccine 2002;20 Suppl 4():A2-7.
2002: Valérie Dutoit; Robert N Taub; Kyriakos P Papadopoulos; Susan Talbot; Mary-Louise Keohan; Michelle Brehm; Sacha Gnjatic; Paul E Harris; Brygida Bisikirska; Philippe Guillaume; Jean-Charles Cerottini; Charles Hesdorffer; Lloyd J Old; Danila Valmori
Multiepitope CD8(+) T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting.
The Journal of clinical investigation 2002;110(12):1813-22.
2002: Verena Rubio-Godoy; Valérie Dutoit; Yingdong Zhao; Richard Simon; Philippe Guillaume; Richard A Houghten; Pedro Romero; Jean-Charles Cerottini; Clemencia Pinilla; Danila Valmori
Positional scanning-synthetic peptide library-based analysis of self- and pathogen-derived peptide cross-reactivity with tumor-reactive Melan-A-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5696-707.
2002: Valérie Dutoit; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes.
European journal of immunology 2002;32(11):3285-93.
2002: Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?
Cancer immunity 2002;2():14.
2002: Pedro Romero; Danila Valmori; Mikaël J Pittet; Alfred Zippelius; Donata Rimoldi; Frédéric Lévy; Valérie Dutoit; Maha Ayyoub; Verena Rubio-Godoy; Olivier Michielin; Philippe Guillaume; Pascal Batard; Immanuel F Luescher; Ferdy Lejeune; Danielle Liénard; Nathalie Rufer; Pierre-Yves Dietrich; Daniel E Speiser; Jean-Charles Cerottini
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Immunological reviews 2002;188():81-96.
2002: Ann M De Mazière; Katja Muehlethaler; Elly van Donselaar; Suzanne Salvi; Jean Davoust; Jean-Charles Cerottini; Frédéric Lévy; Jan W Slot; Donata Rimoldi
The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins.
Traffic (Copenhagen, Denmark) 2002;3(9):678-93.
2002: Verena Rubio-Godoy; Maha Ayyoub; Valérie Dutoit; Catherine Servis; Amy Schink; Donata Rimoldi; Pedro Romero; Jean-Charles Cerottini; Richard Simon; Yindong Zhao; Richard A Houghten; Clemencia Pinilla; Danila Valmori
Combinatorial peptide library-based identification of peptide ligands for tumor-reactive cytolytic T lymphocytes of unknown specificity.
European journal of immunology 2002;32(8):2292-9.
2002: Valérie Dutoit; Verena Rubio-Godoy; Mikaël J Pittet; Alfred Zippelius; Pierre-Yves Dietrich; Frédérique Anne Legal; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Richard A Houghten; Clemencia Pinilla; Danila Valmori
Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans.
The Journal of experimental medicine 2002;196(2):207-16.
2002: Valérie Dutoit; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Danila Valmori
Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition.
Cancer immunity 2002;2():7.
2002: Mikaël J Pittet; Alfred Zippelius; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.
Trends in immunology 2002;23(7):325-8.
2002: Pascal Batard; Janos Szollosi; Immanuel F Luescher; Jean-Charles Cerottini; Rob MacDonald; Pedro Romero
Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations.
Cytometry 2002;48(2):97-105.
2002: Danila Valmori; Valérie Dutoit; Valerie Schnuriger; Anne-Lise Quiquerez; Mikaël J Pittet; Philippe Guillaume; Verena Rubio-Godoy; Paul R Walker; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Pierre-Yves Dietrich
Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4231-40.
2002: Verena Rubio-Godoy; Clemencia Pinilla; Valérie Dutoit; Eva Borras; Richard Simon; Yingdong Zhao; Jean-Charles Cerottini; Pedro Romero; Richard A Houghten; Danila Valmori
Toward synthetic combinatorial peptide libraries in positional scanning format (PS-SCL)-based identification of CD8+ Tumor-reactive T-Cell Ligands: a comparative analysis of PS-SCL recognition by a single tumor-reactive CD8+ cytolytic T-lymphocyte clone.
Cancer research 2002;62(7):2058-63.
2002: Danila Valmori; Carmen Scheibenbogen; Valérie Dutoit; Dirk Nagorsen; Anne Marie Asemissen; Verena Rubio-Godoy; Donata Rimoldi; Philippe Guillaume; Pedro Romero; Dirk Schadendorf; Martin Lipp; Pierre-Yves Dietrich; Eckhard Thiel; Jean-Charles Cerottini; Danielle Liénard; Ulrich Keilholz
Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.
Cancer research 2002;62(6):1743-50.
2002: Daniel E Speiser; Danielle Liénard; Mikaël J Pittet; Pascal Batard; Donata Rimoldi; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
European journal of immunology 2002;32(3):731-41.
2002: Alfred Zippelius; Mikaël J Pittet; Pascal Batard; Nathalie Rufer; Magda De Smedt; Philippe Guillaume; Kim Ellefsen; Danila Valmori; Danielle Liénard; Jean Plum; H Robson MacDonald; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
The Journal of experimental medicine 2002;195(4):485-94.
2002: Maha Ayyoub; Stefan Stevanovic; Ugur Sahin; Philippe Guillaume; Catherine Servis; Donata Rimoldi; Danila Valmori; Pedro Romero; Jean-Charles Cerottini; Hans-Georg Rammensee; Michael Pfreundschuh; Daniel Speiser; Frédéric Lévy
Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1717-22.
2002: Isabelle Miconnet; Sylvain Koenig; Daniel Speiser; Arthur Krieg; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero
CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1212-8.
2002: Valérie Dutoit; Verena Rubio-Godoy; Marie-Agnès Doucey; Pascal Batard; Danielle Liénard; Donata Rimoldi; Daniel Speiser; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1167-71.
2001: Daniel E Speiser; Marco COLONna; Maha Ayyoub; M Cella; Mikaël J Pittet; Pascal Batard; Danila Valmori; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6165-70.
2001: Donata Rimoldi; Katja Muehlethaler; Suzanne Salvi; Danila Valmori; Pedro Romero; Jean-Charles Cerottini; F Levy
Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitope.
The Journal of biological chemistry 2001;276(46):43189-96.
2001: Maha Ayyoub; M Migliaccio; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Frédéric Lévy; Daniel E Speiser; Danila Valmori
Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.
European journal of immunology 2001;31(9):2642-51.
2001: Verena Rubio-Godoy; Valérie Dutoit; Donata Rimoldi; Danielle Lienard; Ferdy Lejeune; Daniel Speiser; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10302-7.
2001: Valérie Dutoit; Verena Rubio-Godoy; Pierre-Yves Dietrich; A L Quiqueres; Valerie Schnuriger; Donata Rimoldi; Danielle Liénard; Daniel Speiser; Philippe Guillaume; Pascal Batard; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.
Cancer research 2001;61(15):5850-6.
2001: Clemencia Pinilla; Verena Rubio-Godoy; Valérie Dutoit; Philippe Guillaume; R Simon; Y Zhao; Richard A Houghten; Jean-Charles Cerottini; P Romero; Danila Valmori
Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes.
Cancer research 2001;61(13):5153-60.
2001: Daniel F Legler; Marie-Agnès Doucey; Jean-Charles Cerottini; Claude Bron; Immanuel F Luescher
Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1601-3.
2001: Mikaël J Pittet; Alfred Zippelius; Daniel E Speiser; M Assenmacher; Philippe Guillaume; Danila Valmori; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7634-40.
2001: Marie-Agnès Doucey; Daniel F Legler; Nicole Boucheron; Jean-Charles Cerottini; Claude Bron; Immanuel F Luescher
CTL activation is induced by cross-linking of TCR/MHC-peptide-CD8/p56lck adducts in rafts.
European journal of immunology 2001;31(5):1561-70.
2001: Isabelle Miconnet; Isabelle Coste; Friedrich Beermann; J F Haeuw; Jean-Charles Cerottini; Jean-Yves Bonnefoy; Pedro Romero; Toufic Renno
Cancer vaccine design: a novel bacterial adjuvant for peptide-specific CTL induction.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4612-9.
2001: Bruno Robert; Philippe Guillaume; Immanuel F Luescher; Marie-Agnès Doucey; Jean-Charles Cerottini; Pedro Romero; Jean-Pierre Mach
Redirecting anti-viral CTL against cancer cells by surface targeting of monomeric MHC class I-viral peptide conjugated to antibody fragments.
Cancer immunity 2001;1():2.
2001: Mikaël J Pittet; Daniel E Speiser; Danielle Liénard; Danila Valmori; Philippe Guillaume; Valérie Dutoit; Donata Rimoldi; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):796s-803s.
2001: Pedro Romero; Valérie Dutoit; Verena Rubio-Godoy; Danielle Liénard; Daniel Speiser; Philippe Guillaume; K Servis; Donata Rimoldi; Jean-Charles Cerottini; Danila Valmori
CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):766s-772s.
2001: Pierre-Yves Dietrich; Paul R Walker; Anne-Lise Quiquerez; Gaëlle Perrin; Valérie Dutoit; Danielle Liénard; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires.
Cancer research 2001;61(5):2047-54.
2001: Daniel E Speiser; M Migliaccio; Mikaël J Pittet; Danila Valmori; Danielle Liénard; F Lejeune; Patrick Reichenbach; Philippe Guillaume; I Lüscher; Jean-Charles Cerottini; Pedro Romero
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
European journal of immunology 2001;31(2):459-66.
2001: Danila Valmori; Valérie Dutoit; Verena Rubio-Godoy; C Chambaz; Danielle Liénard; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Donata Rimoldi
Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.
Cancer research 2001;61(2):509-12.
2000: Donata Rimoldi; Verena Rubio-Godoy; Valérie Dutoit; Danielle Lienard; Suzanne Salvi; Philippe Guillaume; Daniel Speiser; E Stockert; G Spagnoli; Catherine Servis; Jean-Charles Cerottini; Ferdy Lejeune; Pedro Romero; Danila Valmori
Efficient simultaneous presentation of NY-ESO-1/LAGE-1 primary and nonprimary open reading frame-derived CTL epitopes in melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7253-61.
2000: Pascale Jeannin; Toufic Renno; Liliane Goetsch; Isabelle Miconnet; Jean-Pierre Aubry; Yves Delneste; Nathalie Herbault; Thierry Baussant; Giovanni Magistrelli; Caroline Soulas; Pedro Romero; Jean-Charles Cerottini; Jean-Yves Bonnefoy
OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway.
Nature immunology 2000;1(6):502-9.
2000: M Migliaccio; Mario Amacker; T Just; Patrick Reichenbach; Danila Valmori; Jean-Charles Cerottini; Pedro Romero; Markus Nabholz
Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):4978-84.
2000: Isabelle Miconnet; Catherine Servis; Jean-Charles Cerottini; Pedro Romero; Frédéric Lévy
Amino acid identity and/or position determines the proteasomal cleavage of the HLA-A*0201-restricted peptide tumor antigen MAGE-3271-279.
The Journal of biological chemistry 2000;275(35):26892-7.
2000: Danila Valmori; Valérie Dutoit; Danielle Liénard; Donata Rimoldi; Mikaël J Pittet; Patrick Champagne; Kim Ellefsen; U Sahin; Daniel Speiser; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.
Cancer research 2000;60(16):4499-506.
2000: P Brawand; F A Lemonnier; H Robson MacDonald; Jean-Charles Cerottini; Werner Held
Transgenic expression of Ly49A on T cells impairs a specific antitumor response.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1871-6.
2000: Danila Valmori; Valérie Dutoit; Danielle Liénard; Ferdy Lejeune; Daniel Speiser; Donata Rimoldi; Vincenzo Cerundolo; Pierre-Yves Dietrich; Jean-Charles Cerottini; Pedro Romero
Tetramer-guided analysis of TCR beta-chain usage reveals a large repertoire of melan-A-specific CD8+ T cells in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):533-8.
2000: Mikaël J Pittet; Daniel E Speiser; Danila Valmori; Jean-Charles Cerottini; Pedro Romero
Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1148-52.
2000: Danila Valmori; Frédéric Lévy; Isabelle Miconnet; Paul Zajac; Giulio C Spagnoli; Donata Rimoldi; Danielle Liénard; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
Induction of potent antitumor CTL responses by recombinant vaccinia encoding a melan-A peptide analogue.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):1125-31.
1999: Danila Valmori; Jean-François Fonteneau; Salvatore Valitutti; Nadine Gervois; R Dunbar; Danielle Liénard; Donata Rimoldi; Vincenzo Cerundolo; Francine Jotereau; Jean-Charles Cerottini; Daniel E Speiser; Pedro Romero
Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.
International immunology 1999;11(12):1971-80.
1999: P Brawand; Jean-Charles Cerottini; H Robson MacDonald
Hierarchal utilization of different T-cell receptor Vbeta gene segments in the CD8(+)-T-cell response to an immunodominant Moloney leukemia virus-encoded epitope in vivo.
Journal of virology 1999;73(11):9161-9.
1999: Daniel E Speiser; Mikaël J Pittet; Danila Valmori; R Dunbar; Donata Rimoldi; Danielle Liénard; H Robson MacDonald; Jean-Charles Cerottini; Vincenzo Cerundolo; Pedro Romero
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1999;190(6):775-82.
1999: Donata Rimoldi; S Salvi; D Reed; Pierre G Coulie; Victor Jongeneel; Etienne De Plaen; Francis Brasseur; A M Rodriguez; T Boon; Jean-Charles Cerottini
cDNA and protein characterization of human MAGE-10.
International journal of cancer. Journal international du cancer 1999;82(6):901-7.
1999: Mikaël J Pittet; Danila Valmori; P R Dunbar; Daniel E Speiser; Danielle Liénard; Ferdy Lejeune; Katharina Fleischhauer; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
The Journal of experimental medicine 1999;190(5):705-15.
1999: Danila Valmori; Mikaël J Pittet; C Vonarbourg; Donata Rimoldi; Danielle Liénard; Daniel Speiser; R Dunbar; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
Cancer research 1999;59(16):4050-5.
1999: Daniel E Speiser; Danila Valmori; Donata Rimoldi; Mikaël J Pittet; Danielle Liénard; Vincenzo Cerundolo; H Robson MacDonald; Jean-Charles Cerottini; Pedro Romero
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
European journal of immunology 1999;29(6):1990-9.
1999: Danila Valmori; Mikaël J Pittet; Donata Rimoldi; Danielle Liénard; R Dunbar; Vincenzo Cerundolo; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
An antigen-targeted approach to adoptive transfer therapy of cancer.
Cancer research 1999;59(9):2167-73.
1999: H Bour; Olivier Michielin; P Bousso; Jean-Charles Cerottini; H Robson MacDonald
Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4647-56.
1999: Ying Men; Isabelle Miconnet; Danila Valmori; Donata Rimoldi; Jean-Charles Cerottini; Pedro Romero
Assessment of immunogenicity of human Melan-A peptide analogues in HLA-A*0201/Kb transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3566-73.
1999: Danila Valmori; Uzi Gileadi; Catherine Servis; P Rod Dunbar; Jean-Charles Cerottini; Pedro Romero; Vincenzo Cerundolo; Frédéric Lévy
Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.
The Journal of experimental medicine 1999;189(6):895-906.
1999: B Kessler; Olivier Michielin; C L Blanchard; Irina Apostolou; Christiane Delarbre; Gabriel Gachelin; Claude Grégoire; Bernard Malissen; Jean-Charles Cerottini; Florian M Wurm; M Karplus; Immanuel F Luescher
T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivative.
The Journal of biological chemistry 1999;274(6):3622-31.
1998: Danila Valmori; Nadine Gervois; Donata Rimoldi; Jean-François Fonteneau; Anilza Bonelo; Danielle Liénard; L Rivoltini; Francine Jotereau; Jean-Charles Cerottini; Pedro Romero
Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6956-62.
1998: B Kessler; Denis Hudrisier; M Schroeter; Jürg Tschopp; Jean-Charles Cerottini; Immanuel F Luescher
Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6939-46.
1998: Pedro Romero; P R Dunbar; Danila Valmori; Mikaël J Pittet; G S Ogg; Donata Rimoldi; J L Chen; Danielle Liénard; Jean-Charles Cerottini; Vincenzo Cerundolo
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1998;188(9):1641-50.
1998: Denis Hudrisier; B Kessler; Salvatore Valitutti; C Horvath; Jean-Charles Cerottini; Immanuel F Luescher
The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):553-62.
1998: H Bour; C Horvath; C Lurquin; Jean-Charles Cerottini; H Robson MacDonald
Differential requirement for CD4 help in the development of an antigen-specific CD8+ T cell response depending on the route of immunization.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5522-9.
1998: Danila Valmori; Jean-François Fonteneau; C M Lizana; Nadine Gervois; Danielle Liénard; Donata Rimoldi; Victor Jongeneel; Francine Jotereau; Jean-Charles Cerottini; Pedro Romero
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1750-8.
1998: P Brawand; G Biasi; C Horvath; Jean-Charles Cerottini; H Robson MacDonald
Flow-microfluorometric monitoring of oligoclonal CD8+ T cell responses to an immunodominant Moloney leukemia virus-encoded epitope in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1659-65.
1998: Katharina Fleischhauer; Elisabetta Zino; Myriam Arevalo-Herrera; Sócrates Herrera; Danila Valmori; Jean-Charles Cerottini; E Benazzi; Claudio Bordignon; Pedro Romero
Differential expression of HLA-A*02 subtypes in Colombian Blacks and Mestizos.
Tissue antigens 1998;51(2):204-9.
1998: Jean-Charles Cerottini; Danila Valmori; Donata Rimoldi; Pedro Romero
Human tumor immunotherapy. New opportunities as well as new challenges.
Advances in experimental medicine and biology 1998;451():247-50.
1997: B Kessler; Denis Hudrisier; Jean-Charles Cerottini; Immanuel F Luescher
Role of CD8 in aberrant function of cytotoxic T lymphocytes.
The Journal of experimental medicine 1997;186(12):2033-8.
1997: D S Reed; Pedro Romero; Donata Rimoldi; Jean-Charles Cerottini; J Schaack; Victor Jongeneel
Construction and characterization of a recombinant adenovirus directing expression of the MAGE-1 tumor-specific antigen.
International journal of cancer. Journal international du cancer 1997;72(6):1045-55.
1997: Pedro Romero; Nadine Gervois; Joerg Schneider; P Escobar; Danila Valmori; C Pannetier; A Steinle; T Wolfel; Danielle Lienard; Vincent G Brichard; Aline Van Pel; Francine Jotereau; Jean-Charles Cerottini
Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2366-74.
1997: G A Waanders; Donata Rimoldi; Danielle Liénard; S Carrel; Ferdy Lejeune; P Y Dietrich; Jean-Charles Cerottini; Pedro Romero
Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):685-96.
1997: Fabienne Anjuère; Dmitry Kuznetsov; Pedro Romero; Jean-Charles Cerottini; Victor Jongeneel; Immanuel F Luescher
Differential roles of T cell receptor alpha and beta chains in ligand binding among H-2Kd-restricted cytolytic T lymphocyte clones specific for a photoreactive Plasmodium berghei circumsporozoite peptide derivative.
The Journal of biological chemistry 1997;272(13):8505-14.
1997: B M Kessler; P Bassanini; Jean-Charles Cerottini; Immanuel F Luescher
Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative.
The Journal of experimental medicine 1997;185(4):629-40.
1997: Danila Valmori; Danielle Liénard; G Waanders; Donata Rimoldi; Jean-Charles Cerottini; Pedro Romero
Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients.
Cancer research 1997;57(4):735-41.
1997: Jean-Charles Cerottini; Jürg Tschopp
New knowledge about T-cell cytotoxicity.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8 Suppl 2():75-8.
1996: Michael Hahne; Donata Rimoldi; M Schröter; Pedro Romero; M Schreier; Lars E French; Pascal Schneider; T Bornand; A Fontana; D Lienard; Jean-Charles Cerottini; Jürg Tschopp
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
Science (New York, N.Y.) 1996;274(5291):1363-6.
1996: S Carrel; M Schreyer; G Spagnoli; Jean-Charles Cerottini; Donata Rimoldi
Monoclonal antibodies against recombinant-MAGE-1 protein identify a cross-reacting 72-kDa antigen which is co-expressed with MAGE-1 protein in melanoma cells.
International journal of cancer. Journal international du cancer 1996;67(3):417-22.
1996: Immanuel F Luescher; Pedro Romero; D Kuznetsov; Donata Rimoldi; Pierre G Coulie; Jean-Charles Cerottini; Victor Jongeneel
HLA photoaffinity labeling reveals overlapping binding of homologous melanoma-associated gene peptides by HLA-A1, HLA-A29, and HLA-B44.
The Journal of biological chemistry 1996;271(21):12463-71.
1996: Jean-Charles Cerottini; D Liénard; P Romero
Recognition of tumor-associated antigens by T-lymphocytes: perspectives for peptide-based vaccines.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(4):339-42.
1995: Pedro Romero; C Pannetier; J Herman; Victor Jongeneel; Jean-Charles Cerottini; Pierre G Coulie
Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1.
The Journal of experimental medicine 1995;182(4):1019-28.
1995: Fabienne Anjuère; A Layer; Jean-Charles Cerottini; Catherine Servis; Immanuel F Luescher
Synthesis of a radioiodinated photoreactive MAGE-1 peptide derivative and photoaffinity labeling of cell-associated human leukocyte antigen-A1 molecules.
Analytical biochemistry 1995;229(1):61-7.
1995: Immanuel F Luescher; Fabienne Anjuère; Manuel Peitsch; Victor Jongeneel; Jean-Charles Cerottini; Pedro Romero
Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative.
Immunity 1995;3(1):51-63.
1995: Fabienne Anjuère; C Horvath; Jean-Charles Cerottini; Immanuel F Luescher
Induction of CTL in vivo by major histocompatibility complex class I-peptide complexes covalently associated on the cell surface.
European journal of immunology 1995;25(6):1535-40.
1995: H Robson MacDonald; U Bommhardt; Jean-Charles Cerottini
Developmentally regulated expression of P-glycoprotein (multidrug resistance) activity in mouse thymocytes.
European journal of immunology 1995;25(5):1457-60.
1994: U Bommhardt; Jean-Charles Cerottini; H Robson MacDonald
Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: correlation with surface phenotype and effector function.
European journal of immunology 1994;24(12):2974-81.
1994: S Blum; R Milesi; J Tratkiewicz; D Olive; H Gallati; Jean-Charles Cerottini; V von Fliedner
Rapid induction of cytolytic T cells via CD28 stimulation for cellular immunotherapy.
Therapeutic immunology 1994;1(3):143-52.
1994: Pedro Romero; Jean-Charles Cerottini; Immanuel F Luescher
Efficient in vivo induction of CTL by cell-associated covalent H-2Kd-peptide complexes.
Journal of immunological methods 1994;171(1):73-84.
1994: Immanuel F Luescher; Jean-Charles Cerottini; P Romero
Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand.
The Journal of biological chemistry 1994;269(8):5574-82.
1993: H Robson MacDonald; Jean-Laurent Casanova; J L Maryanski; Jean-Charles Cerottini
Oligoclonal expansion of major histocompatibility complex class I-restricted cytolytic T lymphocytes during a primary immune response in vivo: direct monitoring by flow cytometry and polymerase chain reaction.
The Journal of experimental medicine 1993;177(5):1487-92.
1993: P Romero; Jean-Laurent Casanova; Jean-Charles Cerottini; J L Maryanski; Immanuel F Luescher
Differential T cell receptor photoaffinity labeling among H-2Kd restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative. Labeling of the alpha-chain correlates with J alpha segment usage.
The Journal of experimental medicine 1993;177(5):1247-56.
1993: Jean-Laurent Casanova; F Martinon; H Gournier; C Barra; C Pannetier; A Regnault; Philippe Kourilsky; Jean-Charles Cerottini; J L Maryanski
T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position.
The Journal of experimental medicine 1993;177(3):811-20.
1992: J A López; Immanuel F Luescher; Jean-Charles Cerottini
Direct binding of peptides to MHC class I molecules on living cells. Analysis at the single cell level.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3827-35.
1992: Jean-Laurent Casanova; Jean-Charles Cerottini; M Matthes; A Necker; H Gournier; C Barra; C Widmann; H Robson MacDonald; F Lemonnier; Bernard Malissen; J L Maryanski
H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity.
The Journal of experimental medicine 1992;176(2):439-47.
1992: Immanuel F Luescher; J A Lóez; Bernard Malissen; Jean-Charles Cerottini
Interaction of antigenic peptides with MHC class I molecules on living cells studied by photoaffinity labeling.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1003-11.
1992: V von Fliedner; S Miescher; J Gérain; H Gallati; C Barras; Didier Heumann; Jean-Charles Cerottini
Production of tumor necrosis factor-alpha by naive or memory T lymphocytes activated via CD28.
Cellular immunology 1992;139(1):198-207.
1991: Jean-Charles Cerottini; Immanuel F Luescher
Direct analysis of peptide binding to cell-associated MHC class I molecules.
Immunology letters 1991;30(2):171-5.
1991: J L Maryanski; Pedro Romero; Aline Van Pel; T Boon; Francis Salemme; Jean-Charles Cerottini; Giampietro Corradin
The identification of tyrosine as a common key residue in unrelated H-2Kd restricted antigenic peptides.
International immunology 1991;3(10):1035-42.
1991: Immanuel F Luescher; Pedro Romero; Jean-Charles Cerottini; J L Maryanski
Specific binding of antigenic peptides to cell-associated MHC class I molecules.
Nature 1991;351(6321):72-4.
1990: H Robson MacDonald; R C Budd; Jean-Charles Cerottini
Pgp-1 (Ly 24) as a marker of murine memory T lymphocytes.
Current topics in microbiology and immunology 1990;159():97-109.
1989: S Carrel; D Lamarre; P Isler; C Rapin; S Fleury; S Salvi; Rafick-Pierre Sekaly; Jean-Charles Cerottini
A positive signal is transduced via surface CD4 molecules.
Research in immunology 1989;140(5-6):545-61.
1989: Victor Jongeneel; A N Shakhov; Sergei A Nedospasov; Jean-Charles Cerottini
Molecular control of tissue-specific expression at the mouse TNF locus.
European journal of immunology 1989;19(3):549-52.
1989: Jean-Charles Cerottini; H Robson MacDonald
The cellular basis of T-cell memory.
Annual review of immunology 1989;7():77-89.
1989: J L Maryanski; J P Abastado; Giampietro Corradin; Jean-Charles Cerottini
Structural features of peptides recognized by H-2Kd-restricted T cells.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():545-50.
1988: J L Maryanski; P Pala; Jean-Charles Cerottini; H Robson MacDonald
Antigen recognition by H-2-restricted cytolytic T lymphocytes: inhibition of cytolysis by anti-CD8 monoclonal antibodies depends upon both concentration and primary sequence of peptide antigen.
European journal of immunology 1988;18(11):1863-6.
1988: P Isler; S Salvi; C Rapin; L Giuffrè; Jean-Charles Cerottini; S Carrel
Antigen-independent activation of T cells mediated by a novel cell surface heterodimer (Tp135-145).
European journal of immunology 1988;18(10):1491-8.
1988: P Pala; H C Bodmer; R M Pemberton; Jean-Charles Cerottini; J L Maryanski; B A Askonas
Competition between unrelated peptides recognized by H-2-Kd restricted T cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2289-94.
1988: J L Maryanski; P Pala; Jean-Charles Cerottini; Giampietro Corradin
Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.
The Journal of experimental medicine 1988;167(4):1391-405.
1988: Victor Jongeneel; Sergei A Nedospasov; G Plaetinck; P Naquet; Jean-Charles Cerottini
Expression of the tumor necrosis factor locus is not necessary for the cytolytic activity of T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(6):1916-22.
1988: S Carrel; Alessandro Moretta; G Pantaleo; G Tambussi; P Isler; B Perussia; Jean-Charles Cerottini
Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti-CD4 monoclonal antibody.
European journal of immunology 1988;18(3):333-9.
1988: D T Harris; W J Kozumbo; J E Testa; P A Cerutti; Jean-Charles Cerottini
Molecular mechanisms involved in T cell activation. III. The role of extracellular calcium in antigen-induced lymphokine production and interleukin 2-induced proliferation of cloned cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(3):921-7.
1988: P Pala; Giampietro Corradin; T Strachan; R Sodoyer; Bertrand R Jordan; Jean-Charles Cerottini; J L Maryanski
Mapping of HLA epitopes recognized by H-2-restricted cytotoxic T lymphocytes specific for HLA using recombinant genes and synthetic peptides.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(3):871-7.
1988: Jean-Charles Cerottini; R C Budd; H Robson MacDonald
Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells.
Annals of the New York Academy of Sciences 1988;532():68-75.
1987: S Carrel; P Isler; S Salvi; L Giuffrè; G Pantaleo; Jean-Pierre Mach; Jean-Charles Cerottini
Identification of a novel 45-kDa cell surface molecule involved in activation of the human Jurkat T cell line.
European journal of immunology 1987;17(10):1395-402.
1987: D T Harris; W J Kozumbo; P A Cerutti; Jean-Charles Cerottini
Mechanism of cyclosporin A-induced immunosuppression. Cyclosporin A inhibits receptor-mediated and non-receptor-mediated lymphokine production as well as interleukin-2-induced proliferation in cloned T lymphocytes.
Cellular immunology 1987;109(1):104-14.
1987: S Carrel; S Salvi; L Giuffrè; P Isler; Jean-Charles Cerottini
A novel 90-kDa polypeptide (Tp90) possibly involved in an antigen-independent pathway of T cell activation.
European journal of immunology 1987;17(6):835-41.
1987: R C Budd; Jean-Charles Cerottini; C Horvath; Claude Bron; Thierry Pedrazzini; R C Howe; H Robson MacDonald
Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(10):3120-9.
1987: W J Kozumbo; D T Harris; S Gromkowski; Jean-Charles Cerottini; P A Cerutti
Molecular mechanisms involved in T cell activation. II. The phosphatidylinositol signal-transducing mechanism mediates antigen-induced lymphokine production but not interleukin 2-induced proliferation in cloned cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(2):606-12.
1987: D T Harris; W J Kozumbo; P Cerutti; Jean-Charles Cerottini
Molecular mechanisms involved in T cell activation. I. Evidence for independent signal-transducing pathways in lymphokine production vs proliferation in cloned cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(2):600-5.
1986: J L Maryanski; P Pala; Giampietro Corradin; Bertrand R Jordan; Jean-Charles Cerottini
H-2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide.
Nature 1986;324(6097):578-9.