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Maurizio Ceruti

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Maria Grazia Sarpietro; Sara Ottimo; Maria Chiara Giuffrida; Flavio Rocco; Maurizio Ceruti; Francesco Castelli
Synthesis of n-squalenoyl cytarabine and evaluation of its affinity with phospholipid bilayers and monolayers.
S Voyron; Flavio Rocco; Maurizio Ceruti; Paolo Forni; Alessandra Fiorio Pla; Maria Grazia Sarpietro; Giovanna Cristina Varese; Valeria Filipello Marchisio
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase.
Maria Grazia Sarpietro; Flavio Rocco; Dorotea Micieli; Sara Ottimo; Maurizio Ceruti; Francesco Castelli
Interaction of acyclovir and its squalenoyl-acyclovir prodrug with DMPC in monolayers at the air/water interface.

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All Publications

2011: Maria Grazia Sarpietro; Sara Ottimo; Maria Chiara Giuffrida; Flavio Rocco; Maurizio Ceruti; Francesco Castelli
Synthesis of n-squalenoyl cytarabine and evaluation of its affinity with phospholipid bilayers and monolayers.
International journal of pharmaceutics 2011;406(1-2):69-77.
2010: S Voyron; Flavio Rocco; Maurizio Ceruti; Paolo Forni; Alessandra Fiorio Pla; Maria Grazia Sarpietro; Giovanna Cristina Varese; Valeria Filipello Marchisio
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase.
Mycoses 2010;53(6):481-7.
2010: Maria Grazia Sarpietro; Flavio Rocco; Dorotea Micieli; Sara Ottimo; Maurizio Ceruti; Francesco Castelli
Interaction of acyclovir and its squalenoyl-acyclovir prodrug with DMPC in monolayers at the air/water interface.
International journal of pharmaceutics 2010;395(1-2):167-73.
2009: Maria Grazia Sarpietro; Dorotea Micieli; Flavio Rocco; Maurizio Ceruti; Francesco Castelli
Conjugation of squalene to acyclovir improves the affinity for biomembrane models.
International journal of pharmaceutics 2009;382(1-2):73-9.
2007: Francesco Castelli; Maria Grazia Sarpietro; Flavio Rocco; Maurizio Ceruti; Luigi Cattel
Interaction of lipophilic gemcitabine prodrugs with biomembrane models studied by Langmuir-Blodgett technique.
Journal of colloid and interface science 2007;313(1):363-8.
2006: Francesco Castelli; Maria Grazia Sarpietro; Maurizio Ceruti; Flavio Rocco; Luigi Cattel
Characterization of lipophilic gemcitabine prodrug-liposomal membrane interaction by differential scanning calorimetry.
Molecular pharmaceutics 2006;3(6):737-44.
2005: Simonetta Oliaro-Bosso; Maurizio Ceruti; Gianni Balliano; Paola Milla; Flavio Rocco; Franca Viola
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae.
Lipids 2005;40(12):1257-62.
2005: Quanbo Xiong; Flavio Rocco; William K Wilson; Ran Xu; Maurizio Ceruti; Seiichi P T Matsuda
Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis.
The Journal of organic chemistry 2005;70(14):5362-75.
2005: Maurizio Ceruti; Gianni Balliano; Flavio Rocco; Alexander Lenhart; Georg E Schulz; Francesco Castelli; Paola Milla
Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase.
Lipids 2005;40(7):729-35.
2005: Mario Di Braccio; Giancarlo Grossi; Maurizio Ceruti; Flavio Rocco; Roberta Loddo; Giuseppina Sanna; Bernardetta Busonera; Marta Murreddu; Maria Elena Marongiu
1,5-Benzodiazepines XIV. Synthesis of new substituted 9H-bis-[1,2,4]triazolo[4,3-a:3',4'-d] [1,5]benzodiazepines and relate compounds endowed with in vitro cytotoxic properties.
Farmaco (Società chimica italiana : 1989) 2005;60(2):113-25.
2004: Maria Laura Immordino; Paola Brusa; Flavio Rocco; Silvia Arpicco; Maurizio Ceruti; Luigi Cattel
Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(3):331-46.
2004: Luigi Cattel; Maurizio Ceruti; Franco Dosio
From conventional to stealth liposomes: a new Frontier in cancer chemotherapy.
Journal of chemotherapy (Florence, Italy) 2004;16 Suppl 4():94-7.
2004: Silvia Arpicco; Silvana Canevari; Maurizio Ceruti; Enrico Galmozzi; Flavio Rocco; Luigi Cattel
Synthesis, characterization and transfection activity of new saturated and unsaturated cationic lipids.
Farmaco (Società chimica italiana : 1989) 2004;59(11):869-78.
2003: Luigi Cattel; Maurizio Ceruti; Franco Dosio
From conventional to stealth liposomes: a new frontier in cancer chemotherapy.
Tumori 2003;89(3):237-49.
2003: Flavio Rocco; Simonetta Oliaro Bosso; Franca Viola; Paola Milla; Giorgio Roma; Giancarlo Grossi; Maurizio Ceruti
Conjugated methyl sulfide and phenyl sulfide derivatives of oxidosqualene as inhibitors of oxidosqualene and squalene-hopene cyclases.
Lipids 2003;38(3):201-7.
2002: Silvia Arpicco; Franco Dosio; Andrea Bolognesi; Chiara Lubelli; Paola Brusa; Barbara Stella; Maurizio Ceruti; Luigi Cattel
Novel poly(ethylene glycol) derivatives for preparation of ribosome-inactivating protein conjugates.
Bioconjugate chemistry 2002;13(4):757-65.
2001: Maurizio Ceruti; Gianni Balliano; Flavio Rocco; Paola Milla; Silvia Arpicco; Luigi Cattel; Franca Viola
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases.
Lipids 2001;36(6):629-36.
2001: Luigi Cattel; E Buffa; Michele De Simone; P Cesana; S Novello; Franco Dosio; Maurizio Ceruti
Melphalan monitoring during hyperthermic perfusion of isolated limb for melanoma: pharmacokinetic study and 99mTc-albumin microcolloid technique.
Anticancer research 2001;21(3C):2243-8.
2000: Paola Brusa; Maurizio Ceruti; R Casullo; Franco Dosio; G Squiccimarro; Giuseppe Paolo Segoloni; Luigi Cattel
Pharmacokinetic monitoring of mycophenolate mofetil in kidney transplanted patients.
Farmaco (Società chimica italiana : 1989) 2000;55(4):270-5.
2000: Franca Viola; Maurizio Ceruti; Luigi Cattel; Paola Milla; K Poralla; Gianni Balliano
Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase.
Lipids 2000;35(3):297-303.
2000: Maurizio Ceruti; P Crosasso; Paola Brusa; Silvia Arpicco; Franco Dosio; Luigi Cattel
Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing water-soluble prodrugs of paclitaxel.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):141-53.
2000: P Crosasso; Maurizio Ceruti; Paola Brusa; Silvia Arpicco; Franco Dosio; Luigi Cattel
Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):19-30.
2000: Franca Viola; Gianni Balliano; Paola Milla; Luigi Cattel; Flavio Rocco; Maurizio Ceruti
Stereospecific syntheses of trans-vinyldioxidosqualene and 3-hydroxysulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors.
Bioorganic & medicinal chemistry 2000;8(1):223-32.
1999: Maurizio Ceruti; Valentina Tagini; Valeria Recalenda; Silvia Arpicco; Luigi Cattel; Mario Airoldi; Cesare Bumma
Docetaxel in combination with epirubicin in metastatic breast cancer: pharmacokinetic interactions.
Farmaco (Società chimica italiana : 1989) 1999;54(11-12):733-9.
1999: Paola Milla; Franca Viola; Maurizio Ceruti; Flavio Rocco; Luigi Cattel; Gianni Balliano
19-Azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae.
Lipids 1999;34(7):681-8.
1998: Maurizio Ceruti; Flavio Rocco; Franca Viola; Gianni Balliano; Paola Milla; Silvia Arpicco; Luigi Cattel
29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase.
Journal of medicinal chemistry 1998;41(4):540-54.
1998: Luigi Cattel; Maurizio Ceruti
Inhibitors of 2,3-oxidosqualene cyclase as tools for studying the mechanism and function of the enzyme.
Critical reviews in biochemistry and molecular biology 1998;33(5):353-73.
1996: Franco Dosio; A Franceschi; Maurizio Ceruti; Paola Brusa; Luigi Cattel; M Colombatti
Enhancement of ricin toxin A chain immunotoxin activity: synthesis, ionophoretic ability, and in vitro activity of monensin derivatives.
Biochemical pharmacology 1996;52(1):157-66.
1996: D Airaudi; Maurizio Ceruti; C Bianco; V Filipello Marchisio
In vitro susceptibility of fungi to acyclic inhibitors of 2,3-oxidosqualene cyclases.
Mycoses 1996;39(1-2):51-6.
1995: Franca Viola; Paola Brusa; Gianni Balliano; Maurizio Ceruti; O Boutaud; Francis Schuber; Luigi Cattel
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives.
Biochemical pharmacology 1995;50(6):787-96.
1995: D Airaudi; Maurizio Ceruti; A Giannetta; V Filipello Marchisio
Preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes.
Mycoses 1995;38(7-8):311-5.
1995: O Boutaud; Maurizio Ceruti; Luigi Cattel; Francis Schuber
Retention of the label during the conversion of [3-3H] squalene into (3S)-2,3-oxidosqualene catalyzed by mammalian squalene oxidase.
Biochemical and biophysical research communications 1995;208(1):42-7.
1995: Luigi Cattel; Maurizio Ceruti; Gianni Balliano; Franca Viola; G Grosa; Flavio Rocco; Paola Brusa
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors.
Lipids 1995;30(3):235-46.
1994: Gianni Balliano; Paola Milla; Maurizio Ceruti; L Carrano; Franca Viola; Paola Brusa; Luigi Cattel
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide.
Antimicrobial agents and chemotherapy 1994;38(9):1904-8.
1994: G Grosa; Franco Dosio; Paola Brusa; Maurizio Ceruti; L Delprino; Luigi Cattel
2,3,4,5-tetrahydroxy-5-(4-hydroxyphenyl)valeric acid: a new cleavable monofunctional reagent for monoclonal antibody labeling.
Farmaco (Società chimica italiana : 1989) 1994;49(5):349-55.
1994: Franco Dosio; Paola Brusa; L Delprino; G Grosa; Maurizio Ceruti; Luigi Cattel
A new approach in the synthesis of immunotoxins: ribosome inactivating protein noncovalently bound to monoclonal antibody.
Journal of pharmaceutical sciences 1994;83(2):206-11.
1993: L Delprino; M Giacomotti; Franco Dosio; Paola Brusa; Maurizio Ceruti; G Grosa; Luigi Cattel
Toxin-targeted design for anticancer therapy. II: Preparation and biological comparison of different chemically linked gelonin-antibody conjugates.
Journal of pharmaceutical sciences 1993;82(7):699-704.
1993: L Delprino; M Giacomotti; Franco Dosio; Paola Brusa; Maurizio Ceruti; G Grosa; Luigi Cattel
Toxin-targeted design for anticancer therapy. I: Synthesis and biological evaluation of new thioimidate heterobifunctional reagents.
Journal of pharmaceutical sciences 1993;82(5):506-12.
1993: G Grosa; Flavio Rocco; Maurizio Ceruti; Franco Dosio; Paola Brusa; G Biglino
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane, and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study.
Farmaco (Società chimica italiana : 1989) 1993;48(5):677-90.
1993: Gianni Balliano; Paola Milla; Maurizio Ceruti; Franca Viola; L Carrano; Luigi Cattel
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene.
FEBS letters 1993;320(3):203-6.
1993: Franco Dosio; Paola Brusa; L Delprino; Maurizio Ceruti; G Grosa; Luigi Cattel; Andrea Bolognesi; L Barbieri
A new 'solid phase' procedure to synthesize immunotoxins (antibody-ribosome inactivating protein conjugates).
Farmaco (Società chimica italiana : 1989) 1993;48(1):105-15.
1992: G Grosa; Otto Caputo; Maurizio Ceruti; G Biglino
Metabolism of 7-(1,3-thiazolidin-2-ylmethyl)theophylline by rat liver microsomes. Evidence for a monooxygenase-dependent step in 1,3-thiazolidine ring cleavage.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(5):742-6.
1992: Maurizio Ceruti; Gianni Balliano; Franca Viola; G Grosa; Flavio Rocco; Luigi Cattel
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase.
Journal of medicinal chemistry 1992;35(16):3050-8.
1992: Gianni Balliano; Franca Viola; Maurizio Ceruti; Luigi Cattel
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae.
Archives of biochemistry and biophysics 1992;293(1):122-9.
1991: Otto Caputo; G Grosa; Maurizio Ceruti; Flavio Rocco; G Biglino
The metabolic fate of the anti-parkinsonian drug budipine in rats.
European journal of drug metabolism and pharmacokinetics 1991;16(2):113-8.
1991: G Grosa; Otto Caputo; Maurizio Ceruti; G Biglino; J S Franzone; Carlo Cravanzola
Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine by rat liver microsomes. Diastereoselective metabolism of the 1,3-dithiolane ring.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(2):454-7.
1990: Franca Viola; Maurizio Ceruti; Gianni Balliano; Otto Caputo; Luigi Cattel
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase.
Farmaco (Società chimica italiana : 1989) 1990;45(9):965-78.
1990: Otto Caputo; G Grosa; Maurizio Ceruti; Flavio Rocco; G Biglino
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(5):771-8.
1989: Otto Caputo; G Grosa; Maurizio Ceruti; Franca Viola; Flavio Rocco
In vivo metabolism of the anti-inflammatory agent 2-(5-ethylpyridin-2-yl)benzimidazole.
European journal of drug metabolism and pharmacokinetics 1989;14(4):263-8.
1989: Franca Viola; G Grosa; Maurizio Ceruti; Otto Caputo; Luigi Cattel
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes.
Biochemical pharmacology 1989;38(15):2497-503.
1989: Luigi Cattel; Maurizio Ceruti; Gianni Balliano; Franca Viola; G Grosa; Francis Schuber
Drug design based on biosynthetic studies: synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase.
Steroids 1989;53(3-5):363-91.
1988: Gianni Balliano; Franca Viola; Maurizio Ceruti; Luigi Cattel
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae by N,N-diethylazasqualene and derivatives.
Biochimica et biophysica acta 1988;959(1):9-19.
1986: Agostino Pugliese; Valerio Vidotto; Maurizio Ceruti; Alberto Biglino
[Antiproliferative effect of an extract of Aspergillus terreus].
Giornale di batteriologia, virologia ed immunologia 1986;79(7-12):272-8.
1986: A Ceruti; Maurizio Ceruti; G Vigolo
[Natural antitumor compounds of vegetable origin].
Giornale di batteriologia, virologia ed immunologia 1986;79(7-12):187-98.
1986: Luigi Cattel; Maurizio Ceruti; Franca Viola; L Delprino; Gianni Balliano; A Duriatti; P Bouvier-Navé
The squalene-2,3-epoxide cyclase as a model for the development of new drugs.
Lipids 1986;21(1):31-8.
1986: A Pugliese; Valerio Vidotto; L Parisi; M Vitale; G Schioppacassi; Maurizio Ceruti; P A Tovo
In vitro activity of alpha, beta, gamma human interferons and Aspergillus terreus mycotoxins on cell proliferation.
Bollettino dell'Istituto sieroterapico milanese 1986;65(6):530-7.