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Gaétan Guillemette

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Nathalie Nguyen; Elie Simard; Eric Béliveau; Michael Biet; Robert Dumaine; Nancy Francoeur; michel Grandbois; Gaétan Guillemette; Guylain Boulay
STIM1 participates in the contractile rhythmicity of HL-1 cells by moderating T-type Ca(2+) channel activity.
Dany Fillion; Gaétan Guillemette; Pierre Lavigne; Richard Leduc; Jérôme Cabana; Emanuel Escher
Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode.
Ghadi Elkoreh; Gaétan Guillemette; Eric Béliveau; Véronique Blais; Jean-Bernard Denault
Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis.

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2013: Nathalie Nguyen; Elie Simard; Eric Béliveau; Michael Biet; Robert Dumaine; Nancy Francoeur; michel Grandbois; Gaétan Guillemette; Guylain Boulay
STIM1 participates in the contractile rhythmicity of HL-1 cells by moderating T-type Ca(2+) channel activity.
Biochimica et biophysica acta 2013;1833(6):1294-303.
2013: Dany Fillion; Gaétan Guillemette; Pierre Lavigne; Richard Leduc; Jérôme Cabana; Emanuel Escher
Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode.
The Journal of biological chemistry 2013;288(12):8187-97.
2012: Ghadi Elkoreh; Gaétan Guillemette; Eric Béliveau; Véronique Blais; Jean-Bernard Denault
Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis.
Journal of cellular biochemistry 2012;113(8):2775-84.
2011: Èric Béliveau; Fanny Lapointe; Gaétan Guillemette
The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells.
Journal of cellular biochemistry 2011;112(12):3722-31.
2011: Marc-Olivier Frégeau; Yannik Régimbald-Dumas; Gaétan Guillemette
Positive regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by mammalian target of rapamycin (mTOR) in RINm5F cells.
Journal of cellular biochemistry 2011;112(2):723-33.
2010: Jason Arsenault; Jérôme Cabana; Dany Fillion; Richard Leduc; Gaétan Guillemette; Pierre Lavigne; Emanuel Escher
Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism.
Biochemical pharmacology 2010;80(7):990-9.
2010: Dany Fillion; Guillaume Lemieux; Luta Luse Basambombo; Pierre Lavigne; Gaétan Guillemette; Richard Leduc; Emanuel Escher
The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1.
Journal of medicinal chemistry 2010;53(5):2063-75.
2010: Liping Yan; Brian J Holleran; Pierre Lavigne; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis.
The Journal of biological chemistry 2010;285(4):2284-93.
2010: Guillaume Arguin; Annabelle Caron; Ghadi Elkoreh; Jean-Bernard Denault; Gaétan Guillemette
The transcription factors NFAT and CREB have different susceptibilities to the reduced Ca2+ responses caused by the knock down of inositol trisphosphate receptor in HEK 293A cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;26(4-5):629-40.
2009: Ivana Domazet; Stéphane S Martin; Brian J Holleran; Marie-Eve Morin; Patrick Lacasse; Pierre Lavigne; Emanuel Escher; Richard Leduc; Gaétan Guillemette
The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation.
The Journal of biological chemistry 2009;284(46):31953-61.
2009: Martin Clément; Jérôme Cabana; Brian J Holleran; Richard Leduc; Gaétan Guillemette; Pierre Lavigne; Emanuel Escher
Activation induces structural changes in the liganded angiotensin II type 1 receptor.
The Journal of biological chemistry 2009;284(39):26603-12.
2009: Ivana Domazet; Brian J Holleran; Stéphane S Martin; Pierre Lavigne; Richard Leduc; Emanuel Escher; Gaétan Guillemette
The second transmembrane domain of the human type 1 angiotensin II receptor participates in the formation of the ligand binding pocket and undergoes integral pivoting movement during the process of receptor activation.
The Journal of biological chemistry 2009;284(18):11922-9.
2009: Nathalie Nguyen; Nancy Francoeur; Valérie Chartrand; Klaus Klarskov; Gaétan Guillemette; Guylain Boulay
Insulin promotes the association of heat shock protein 90 with the inositol 1,4,5-trisphosphate receptor to dampen its Ca2+ release activity.
Endocrinology 2009;150(5):2190-6.
2009: Brian J Holleran; Ivana Domazet; Marie-Eve Beaulieu; Li Ping Yan; Gaétan Guillemette; Pierre Lavigne; Emanuel Escher; Richard Leduc
Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor.
Biochemical pharmacology 2009;77(8):1374-82.
2009: Charles Cuerrier; Martin Benoit; Gaétan Guillemette; Fernand Gobeil; michel Grandbois
Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy.
Pflügers Archiv : European journal of physiology 2009;457(6):1361-72.
2009: Eric Béliveau; Gaétan Guillemette
Microfilament and microtubule assembly is required for the propagation of inositol trisphosphate receptor-induced Ca2+ waves in bovine aortic endothelial cells.
Journal of cellular biochemistry 2009;106(2):344-52.
2009: Martin Clément; Gaétan Guillemette; Richard Leduc; Emanuel Escher
Structural changes in the binding pocket of the liganded angiotensin II receptor AT1 during activation.
Advances in experimental medicine and biology 2009;611():341-2.
2009: Julie Arsenault; M P La-Haye Renaud; Martin Clément; Dany Fillion; Gaétan Guillemette; Richard Leduc; Pierre Lavigne; Emanuel Escher
Temperature-induced ligand contact point variations of the hAT1 receptor and of the constitutively active mutant N111G-hAT1.
Advances in experimental medicine and biology 2009;611():339-40.
2009: Dany Fillion; Gaétan Guillemette; Richard Leduc; Emanuel Escher
Photoprobe peptides to map the interactions of angiotensin II with its receptor AT1.
Advances in experimental medicine and biology 2009;611():329-30.
2008: Christophe D Proulx; Brian J Holleran; Antony A Boucard; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor.
Molecular pharmacology 2008;74(3):552-61.
2008: Christophe D Proulx; Brian J Holleran; Pierre Lavigne; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Biological properties and functional determinants of the urotensin II receptor.
Peptides 2008;29(5):691-9.
2008: Patrice C Leclerc; Christophe D Proulx; Guillaume Arguin; Simon Bélanger; Fernand Gobeil; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Ascorbic acid decreases the binding affinity of the AT1 receptor for angiotensin II.
American journal of hypertension 2008;21(1):67-71.
2007: Julie Arsenault; M P La Haye Renaud; M Clément; Dany Fillion; Gaétan Guillemette; Richard Leduc; Pierre Lavigne; Emanuel Escher
Temperature-dependent variations of ligand-receptor contact points in hAT(1).
Journal of peptide science : an official publication of the European Peptide Society 2007;13(9):575-80.
2007: Annabelle Caron; Benoit Chaloux; Guillaume Arguin; Gaétan Guillemette
Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells.
Cell calcium 2007;42(3):323-31.
2007: Stéphane S Martin; Brian J Holleran; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method.
Molecular pharmacology 2007;72(1):182-90.
2007: Benoit Chaloux; Annabelle Caron; Gaétan Guillemette
Protein kinase A increases the binding affinity and the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 2007;99(7):379-88.
2007: Yannik Regimbald-Dumas; Guillaume Arguin; Marc-Olivier Frégeau; Gaétan Guillemette
cAMP-dependent protein kinase enhances inositol 1,4,5-trisphosphate-induced Ca2+ release in AR4-2J cells.
Journal of cellular biochemistry 2007;101(3):609-18.
2007: Guillaume Arguin; Yannik Regimbald-Dumas; Marc-Olivier Frégeau; Annabelle Caron; Gaétan Guillemette
Protein kinase C phosphorylates the inositol 1,4,5-trisphosphate receptor type 2 and decreases the mobilization of Ca2+in pancreatoma AR4-2J cells.
The Journal of endocrinology 2007;192(3):659-68.
2006: Patrice C Leclerc; Pascal M Lanctot; Mannix Auger-Messier; Emanuel Escher; Richard Leduc; Gaétan Guillemette
S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II.
British journal of pharmacology 2006;148(3):306-13.
2006: Pascal M Lanctôt; Patrice C Leclerc; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor.
Biochemical and biophysical research communications 2006;340(2):395-402.
2006: Martin Clément; Caroline Chamberland; Jacqueline Pérodin; Richard Leduc; Gaétan Guillemette; Emanuel Escher
The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: an MPA study on a constitutively active angiotensin II receptor mutant.
Journal of receptor and signal transduction research 2006;26(5-6):417-33.
2005: Pascal M Lanctot; Patrice C Leclerc; Martin Clément; Mannix Auger-Messier; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor.
The Biochemical journal 2005;390(Pt 1):367-76.
2005: Mannix Auger-Messier; Eric S Turgeon; Richard Leduc; Emanuel Escher; Gaétan Guillemette
The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells.
Experimental cell research 2005;308(1):188-95.
2005: Martin Clément; Stéphane S Martin; Marie-Eve Beaulieu; Caroline Chamberland; Pierre Lavigne; Richard Leduc; Gaétan Guillemette; Emanuel Escher
Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay.
The Journal of biological chemistry 2005;280(29):27121-9.
2005: Marc-Antoine Moris; Annabelle Caron; Gaétan Guillemette; Didier Rognan; Martine Schmitt; Gilbert Schlewer
Synthesis of (+/-)-2-O-[4'-(N-9''-purinyl)butyl] myo-inositol 1,4,5-tris(phosphate), a potent full agonist at the D-myo-inositol 1,4,5-tris(phosphate) receptor.
Journal of medicinal chemistry 2005;48(4):1251-5.
2005: Joelle Guillemette; Annabelle Caron; Yannik Regimbald-Dumas; Guillaume Arguin; Gregory A Mignery; Guylain Boulay; Gaétan Guillemette
Expression of a truncated form of inositol 1,4,5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1,4,5-trisphosphate receptor-knockout cells.
Cell calcium 2005;37(2):97-104.
2005: Christophe D Proulx; May Simaan; Emanuel Escher; Stephane Laporte; Gaétan Guillemette; Richard Leduc
Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.
The Biochemical journal 2005;385(Pt 1):115-23.
2004: Stéphane S Martin; Antony A Boucard; Martin Clément; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
The Journal of biological chemistry 2004;279(49):51415-23.
2004: Mannix Auger-Messier; Guillaume Arguin; Benoit Chaloux; Richard Leduc; Emanuel Escher; Gaétan Guillemette
Down-regulation of inositol 1,4,5-trisphosphate receptor in cells stably expressing the constitutively active angiotensin II N111G-AT(1) receptor.
Molecular endocrinology (Baltimore, Md.) 2004;18(12):2967-80.
2004: Marc-Antoine Moris; Annabelle Caron; Gaétan Guillemette; Gilbert Schlewer
Synthesis and binding properties of cyclopentane analogues of myo-inositol 1,4,5-tris(phosphate).
Bioorganic & medicinal chemistry 2004;12(15):3995-4001.
2003: Mannix Auger-Messier; Martin Clement; Pascal M Lanctot; Patrice C Leclerc; Richard Leduc; Emanuel Escher; Gaétan Guillemette
The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha.
Endocrinology 2003;144(12):5277-84.
2003: Antony A Boucard; Marise Roy; Marie-Eve Beaulieu; Pierre Lavigne; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket.
The Journal of biological chemistry 2003;278(38):36628-36.
2003: Annabelle Caron; Guillaume Arguin; Gaétan Guillemette
Angiotensin IV interacts with a juxtamembrane site on AT(4)/IRAP suggesting an allosteric mechanism of enzyme modulation.
Regulatory peptides 2003;113(1-3):9-15.
2003: Antony A Boucard; Simon Sauvé; Gaétan Guillemette; Emanuel Escher; Richard Leduc
Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain.
The Biochemical journal 2003;370(Pt 3):829-38.
2002: Jacqueline Pérodin; Maud Deraët; Mannix Auger-Messier; Antony A Boucard; Lenka Rihakova; Marie-Eve Beaulieu; Pierre Lavigne; Jean-Luc Parent; Gaétan Guillemette; Richard Leduc; Emanuel Escher
Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.
Biochemistry 2002;41(48):14348-56.
2002: Patrice C Leclerc; Mannix Auger-Messier; Pascal M Lanctot; Emanuel Escher; Richard Leduc; Gaétan Guillemette
A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling.
Endocrinology 2002;143(12):4702-10.
2002: Maud Deraët; Lenka Rihakova; Antony A Boucard; J Pèrodin; Simon Sauvé; Axel P Mathieu; Gaétan Guillemette; Richard Leduc; Pierre Lavigne; Emanuel Escher
Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form.
Canadian journal of physiology and pharmacology 2002;80(5):418-25.
2002: Lenka Rihakova; Maud Deraët; Mannix Auger-Messier; Jacqueline Pérodin; Antony A Boucard; Gaétan Guillemette; Richard Leduc; Pierre Lavigne; Emanuel Escher
Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction.
Journal of receptor and signal transduction research 2002;22(1-4):297-313.
2002: Karina Laflamme; Olivier Domingue; Benoit I Guillemette; Gaétan Guillemette
Immunohistochemical localization of type 2 inositol 1,4,5-trisphosphate receptor to the nucleus of different mammalian cells.
Journal of cellular biochemistry 2002;85(1):219-28.
2001: SN Poirier; M Poitras; Karina Laflamme; Gaétan Guillemette
Thiol-reactive agents biphasically regulate inositol 1,4,5-trisphosphate binding and Ca(2+) release activities in bovine adrenal cortex microsomes.
Endocrinology 2001;142(6):2614-21.
2001: SN Poirier; M Poitras; Alzbeta Chorvatova; Marcel D Payet; Gaétan Guillemette
FK506 blocks intracellular Ca2+ oscillations in bovine adrenal glomerulosa cells.
Biochemistry 2001;40(21):6486-92.
2001: Pierre J Farmer; SG Bernier; Andrée Lepage; Gaétan Guillemette; Domenico Regoli; Pierre Sirois
Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L732-8.
2001: Stephane Pelletier; J Dubé; A Villeneuve; Fernand Gobeil; Q Yang; Bruno Battistini; Gaétan Guillemette; Pierre Sirois
Prostaglandin E(2) increases cyclic AMP and inhibits endothelin-1 production/secretion by guinea-pig tracheal epithelial cells through EP(4) receptors.
British journal of pharmacology 2001;132(5):999-1008.
2001: Jacqueline Pérodin; Antony A Boucard; Richard Leduc; Emanuel Escher; Gaétan Guillemette
Assays for radiolabel-photoaffinity labeling of Angiotensin receptors.
Methods in molecular medicine 2001;51():297-303.
2000: Antony A Boucard; B C Wilkes; Stephane Laporte; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure.
Biochemistry 2000;39(32):9662-70.
2000: M J Gosselin; Patrice C Leclerc; Mannix Auger-Messier; Gaétan Guillemette; Emanuel Escher; Richard Leduc
Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding.
Biochimica et biophysica acta 2000;1497(1):94-102.
2000: M Poitras; SN Poirier; Karina Laflamme; M Simoneau; Emanuel Escher; Gaétan Guillemette
Different populations of inositol 1,4,5-trisphosphate receptors expressed in the bovine adrenal cortex.
Receptors & channels 2000;7(1):41-52.
2000: Stephane Pelletier; J Dubé; A Villeneuve; Fernand Gobeil; SG Bernier; Bruno Battistini; Gaétan Guillemette; Pierre Sirois
Adenosine induces cyclic-AMP formation and inhibits endothelin-1 production/secretion in guinea-pig tracheal epithelial cells through A(2B) adenosine receptors.
British journal of pharmacology 2000;129(2):243-50.
1999: SI Briand; Witold Neugebauer; Gaétan Guillemette
Agonist-dependent AT(4) receptor internalization in bovine aortic endothelial cells.
Journal of cellular biochemistry 1999;75(4):587-97.
1999: S Ballereau; P Guédat; SN Poirier; Gaétan Guillemette; Bernard Spiess; Gilbert Schlewer
Synthesis, acid-base behavior, and binding properties of 6-modified myo-inositol 1,4,5-tris(phosphate)s.
Journal of medicinal chemistry 1999;42(23):4824-35.
1999: P M Lanctôt; Patrice C Leclerc; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Role of N-glycosylation in the expression and functional properties of human AT1 receptor.
Biochemistry 1999;38(27):8621-7.
1999: Stephane Laporte; Antony A Boucard; Guy Servant; Gaétan Guillemette; Richard Leduc; Emanuel Escher
Determination of peptide contact points in the human angiotensin II type I receptor (AT1) with photosensitive analogs of angiotensin II.
Molecular endocrinology (Baltimore, Md.) 1999;13(4):578-86.
1999: L Chrétien; Stephane Laporte; Emanuel Escher; Richard Leduc; Gaétan Guillemette
The bradykinin B2 receptor couples less efficiently than the angiotensin AT1 receptor to the G protein Gq in transiently transfected COS-7 cells.
Receptors & channels 1999;6(6):425-33.
1998: SI Briand; J M Bellemare; SG Bernier; Gaétan Guillemette
Study on the functionality and molecular properties of the AT4 receptor.
Endocrine research 1998;24(3-4):315-23.
1998: SG Bernier; J M Bellemare; Emanuel Escher; Gaétan Guillemette
Characterization of AT4 receptor from bovine aortic endothelium with photosensitive analogues of angiotensin IV.
Biochemistry 1998;37(12):4280-7.
1998: L Chrétien; DE Richard; SN Poirier; M Poitras; Gaétan Guillemette
Bovine adrenal glomerulosa cells express such a low level of functional B2 receptors that bradykinin does not significantly increase their aldosterone production.
The Journal of endocrinology 1998;156(3):449-60.
1998: R Bouley; Jacqueline Pérodin; H Plante; Lenka Rihakova; SG Bernier; L Maletínská; Gaétan Guillemette; Emanuel Escher
N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor.
European journal of pharmacology 1998;343(2-3):323-31.
1998: Guy Servant; Emanuel Escher; Gaétan Guillemette
The angiotensin II binding site on Mycoplasma hyorhynis is structurally distinct from mammalian AT1 and AT2 receptors.
Regulatory peptides 1998;73(1):35-41.
1998: SI Briand; SG Bernier; Gaétan Guillemette
Monitoring of phospholipase A2 activation in cultured cells using tritiated arachidonic acid.
Methods in molecular biology (Clifton, N.J.) 1998;105():161-6.
1998: M Poitras; A Sidibé; DE Richard; L Chrétien; Gaétan Guillemette
Effect of uncoupling agents on AT1 receptor affinity for antagonist analogs of angiotensin II.
Receptors & channels 1998;6(1):65-72.
1998: Stephane Laporte; S F Roy; Emanuel Escher; Gaétan Guillemette; Richard Leduc
Essential role of leucine222 in mediating signal transduction of the human angiotensin II type 1 receptor.
Receptors & channels 1998;5(2):103-12.
1997: DE Richard; Stephane Laporte; SG Bernier; Richard Leduc; Gaétan Guillemette
Desensitization of AT1 receptor-mediated cellular responses requires long term receptor down-regulation in bovine adrenal glomerulosa cells.
Endocrinology 1997;138(9):3828-35.
1997: L Chrétien; Stephane Laporte; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Use of LiCl in phospholipase C assays masks the impaired functionality of a mutant angiotensin II receptor.
Cellular signalling 1997;9(5):379-82.
1997: S F Roy; Stephane Laporte; Emanuel Escher; Richard Leduc; Gaétan Guillemette
Epitope tagging and immunoreactivity of the human angiotensin II type 1 receptor.
Canadian journal of physiology and pharmacology 1997;75(6):690-5.
1997: R Bouley; M Gosselin; H Plante; Guy Servant; Jacqueline Pérodin; M Arcand; Gaétan Guillemette; Emanuel Escher
Characterization of a specific binding site for angiotensin II in chicken liver.
Canadian journal of physiology and pharmacology 1997;75(6):568-75.
1997: DE Richard; L Chrétien; M Caron; Gaétan Guillemette
Stimulation of the angiotensin II type I receptor on bovine adrenal glomerulosa cells activates a temperature-sensitive internalization-recycling pathway.
Molecular and cellular endocrinology 1997;129(2):209-18.
1997: Guy Servant; Stephane Laporte; Richard Leduc; Emanuel Escher; Gaétan Guillemette
Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs.
The Journal of biological chemistry 1997;272(13):8653-9.
1997: D Dumitriu; S Prié; SG Bernier; Gaétan Guillemette; Pierre Sirois
Mechanism of action of leukotriene D4 on guinea pig tracheal smooth muscle cells: roles of Ca++ influx and intracellular Ca++ release.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1357-65.
1996: S I Briand; SG Bernier; Gaétan Guillemette
Calcium-calmodulin plays a major role in bradykinin-induced arachidonic acid release by bovine aortic endothelial cells.
Journal of cellular biochemistry 1996;63(3):292-301.
1996: Stephane Laporte; Guy Servant; DE Richard; Emanuel Escher; Gaétan Guillemette; Richard Leduc
The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization.
Molecular pharmacology 1996;49(1):89-95.
1996: Guy Servant; D T Dudley; Emanuel Escher; Gaétan Guillemette
Analysis of the role of N-glycosylation in cell-surface expression and binding properties of angiotensin II type-2 receptor of rat pheochromocytoma cells.
The Biochemical journal 1996;313 ( Pt 1)():297-304.
1995: SG Bernier; Guy Servant; M Boudreau; Alain Fournier; Gaétan Guillemette
Characterization of a binding site for angiotensin IV on bovine aortic endothelial cells.
European journal of pharmacology 1995;291(2):191-200.
1995: S Prié; Gaétan Guillemette; Guylain Boulay; Pierre Borgeat; Pierre Sirois
Leukotriene C4 receptors on guinea pig tracheocytes.
The Journal of pharmacology and experimental therapeutics 1995;275(1):312-8.
1995: M Poitras; R M Ribeiro-Do-Valle; S N Poirier; Gaétan Guillemette
Bidirectional activity of the endoplasmic reticulum Ca(2+)-ATPase of bovine adrenal cortex.
Biochemistry 1995;34(30):9755-61.
1995: Marc J Servant; Gaétan Guillemette; Jean Morisset
Pancreatic acinar-cell desensitization alters InsP3 production and Ca2+ mobilization under conditions where InsP3 receptor remains intact.
The Biochemical journal 1995;305 ( Pt 1)():103-10.
1994: SG Bernier; Alain Fournier; Gaétan Guillemette
A specific binding site recognizing a fragment of angiotensin II in bovine adrenal cortex membranes.
European journal of pharmacology 1994;271(1):55-63.
1994: Guylain Boulay; L Chrétien; DE Richard; Gaétan Guillemette
Short-term desensitization of the angiotensin II receptor of bovine adrenal glomerulosa cells corresponds to a shift from a high to a low affinity state.
Endocrinology 1994;135(5):2130-6.
1994: Marc J Servant; Gaétan Guillemette; Jean Morisset
Pharmacologic characterization of the inositol trisphosphate receptor in rat pancreas.
Pancreas 1994;9(5):591-8.
1994: Guy Servant; D T Dudley; Emanuel Escher; Gaétan Guillemette
The marked disparity between the sizes of angiotensin type 2 receptors from different tissues is related to different degrees of N-glycosylation.
Molecular pharmacology 1994;45(6):1112-8.
1994: L Chrétien; Gaétan Guillemette; D Regoli
Non-peptide angiotensin receptor antagonists bind to tachykinin NK3 receptors of rat and guinea pig brain.
European journal of pharmacology 1994;256(1):73-8.
1994: DE Richard; SG Bernier; Guylain Boulay; Gaétan Guillemette
Selective interaction of chemical dyes with inositol 1,4,5-trisphosphate recognition sites.
Canadian journal of physiology and pharmacology 1994;72(2):174-81.
1994: R M Ribeiro-do-Valle; M Poitras; Guylain Boulay; Gaétan Guillemette
The important discrepancy between the apparent affinity observed in Ca2+ mobilization studies and the Kd measured in binding studies is a consequence of the quantal process by which inositol 1,4,5-trisphosphate releases Ca2+ from bovine adrenal cortex microsomes.
Cell calcium 1994;15(1):79-88.
1993: M Poitras; SG Bernier; Marc J Servant; DE Richard; Guylain Boulay; Gaétan Guillemette
The high affinity state of inositol 1,4,5-trisphosphate receptor is a functional state.
The Journal of biological chemistry 1993;268(32):24078-82.
1993: Guy Servant; Guylain Boulay; R Bossé; Emanuel Escher; Gaétan Guillemette
Photoaffinity labeling of subtype 2 angiotensin receptor of human myometrium.
Molecular pharmacology 1993;43(5):677-83.
1993: R Bossé; Guy Servant; L M Zhou; Guylain Boulay; Gaétan Guillemette; Emanuel Escher
Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor.
Regulatory peptides 1993;44(2):215-23.
1993: SG Bernier; Gaétan Guillemette
Increased inositol 1,4,5-trisphosphate binding capacity in vascular smooth muscle of spontaneously hypertensive rats.
American journal of hypertension 1993;6(3 Pt 1):217-25.
1993: M Poitras; SG Bernier; Guylain Boulay; Alain Fournier; Gaétan Guillemette
Interaction of benzene 1,2,4-trisphosphate with inositol 1,4,5-trisphosphate receptor and metabolizing enzymes.
European journal of pharmacology 1993;244(3):203-10.
1992: C Tousignant; L Chrétien; Gaétan Guillemette; D Regoli
Characterization of NK-1 receptors in guinea pig and rat brain membranes with NK-1 peptides and a non-peptide antagonist.
Brain research 1992;596(1-2):243-50.
1992: Guylain Boulay; Guy Servant; T T Luong; Emanuel Escher; Gaétan Guillemette
Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa.
Molecular pharmacology 1992;41(4):809-15.
1992: T T Luong; Guylain Boulay; Gaétan Guillemette
Study on the stereoselectivity of inositol 1,4,5-trisphosphate recognition sites of bovine adrenal cortex.
Canadian journal of physiology and pharmacology 1992;70(4):434-41.
1992: C Tousignant; D Regoli; Nour-Eddine Rhaleb; D Jukic; Gaétan Guillemette
Characterization of a novel binding site for 125I-Tyr-D-Arg-[Hyp3,D-Phe7,Leu8]bradykinin on epithelial membranes of guinea pig ileum.
European journal of pharmacology 1992;225(3):235-44.
1992: C Tousignant; D Regoli; Nour-Eddine Rhaleb; D Jukic; Gaétan Guillemette
125I-Tyr,D-Arg[Hyp3,D-Phe7,Leu8]BK, a radiolabelled B2 antagonist specifically interacts with two distinct binding sites on epithelial membranes of guinea pig ileum.
Agents and actions. Supplements 1992;38 ( Pt 1)():526-39.
1991: Artur J de Brum-Fernandes; Gaétan Guillemette; Pierre Borgeat; Pierre Sirois
Specific binding sites for leukotriene B4 in guinea pig brain membranes.
The Journal of pharmacology and experimental therapeutics 1991;259(3):1035-42.
1991: T T Luong; M Poitras; Guylain Boulay; Gaétan Guillemette
Interaction of polyanions with the recognition sites for inositol 1,4,5-trisphosphate in the bovine adrenal cortex.
European journal of pharmacology 1991;208(3):213-21.
1991: C Tousignant; Gaétan Guillemette; D Regoli
Binding sites for [3H][Sar9, Met(O2)11]substance P in rat brain and guinea pig ileum.
Brain research 1991;560(1-2):1-11.
1991: C Tousignant; Gaétan Guillemette; J Barabé; Nour-Eddine Rhaleb; D Regoli
Characterization of kinin binding sites: identity of B2 receptors in the epithelium and the smooth muscle of the guinea pig ileum.
Canadian journal of physiology and pharmacology 1991;69(6):818-25.
1991: Gaétan Guillemette; M Poitras; Guylain Boulay
Two Ca2+ transport systems are distinguished on the basis of their Mg2+ dependency in a post-nuclear particulate fraction of bovine adrenal cortex.
Cell calcium 1991;12(1):51-60.
1990: Gaétan Guillemette; I Favreau; Guylain Boulay; M Potier
Solubilization and partial characterization of inositol 1,4,5-trisphosphate receptor of bovine adrenal cortex reveal similarities with the receptor of rat cerebellum.
Molecular pharmacology 1990;38(6):841-7.
1990: Artur J de Brum-Fernandes; Gaétan Guillemette; Pierre Sirois
Leukotriene B4 binding sites in guinea-pig alveolar macrophages.
Prostaglandins 1990;40(5):515-27.
1990: Guylain Boulay; Nicole Gallo-Payet; Gaétan Guillemette
Implication of phospholipase C in the steroidogenic action of angiotensin II.
European journal of pharmacology 1990;189(4-5):267-75.
1990: C Tousignant; Gaétan Guillemette; G Drapeau; S Télémaque; SB Dion; D Regoli
125I-BH[Sar9, Met(O2)11]-SP, a new selective ligand for the NK-1 receptor in the central nervous system.
Brain research 1990;524(2):263-70.
1990: Gaétan Guillemette; I Favreau; S Lamontagne; Guylain Boulay
2,3-Diphosphoglycerate is a nonselective inhibitor of inositol 1,4,5-trisphosphate action and metabolism.
European journal of pharmacology 1990;188(4-5):251-60.
1989: C Tousignant; Gaétan Guillemette; G Drapeau; D Regoli
Comparison of binding assay and biological activity on a NK-1 system with new selective agonists.
Neuropeptides 1989;14(4):275-83.
1989: Gaétan Guillemette; Guylain Boulay; S Gagnon; Roger Bosse; Emanuel Escher
The peptide encoded by angiotensin II complementary RNA does not interfere with angiotensin II action.
The Biochemical journal 1989;261(1):309.
1989: Gaétan Guillemette; S Lamontagne; Guylain Boulay; B Mouillac
Differential effects of heparin on inositol 1,4,5-trisphosphate binding, metabolism, and calcium release activity in the bovine adrenal cortex.
Molecular pharmacology 1989;35(3):339-44.
1988: Gaétan Guillemette; J A Segui
Effects of pH, reducing and alkylating reagents on the binding and Ca2+ release activities of inositol 1,4,5-triphosphate in the bovine adrenal cortex.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1249-55.