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Constance Jeffery

Research Profile

Procedures

X Ray Crystallography

Chemicals & Drugs

Concepts & Ideas

Phenomena

Living Beings

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Binding, Competitive

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Publications

TOP 3
Grant L Zwicke; G Ali Mansoori; Constance J Jeffery
Utilizing the folate receptor for active targeting of cancer nanotherapeutics.
Constance J Jeffery
Danish Team wins First BIOMOD International Undergraduate Nanobiology Design Competition.
Constance J Jeffery
Workshop attendees suggest methods to improve the number and advancement of women scientists in NanoScience/NanoTechnology.

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All Publications

2012: Grant L Zwicke; G Ali Mansoori; Constance J Jeffery
Utilizing the folate receptor for active targeting of cancer nanotherapeutics.
Nano reviews 2012;3():.
2012: Constance J Jeffery
Danish Team wins First BIOMOD International Undergraduate Nanobiology Design Competition.
Nano reviews 2012;3():.
2012: Constance J Jeffery
Workshop attendees suggest methods to improve the number and advancement of women scientists in NanoScience/NanoTechnology.
Nano reviews 2012;3():.
2011: Constance J Jeffery
Proteins with neomorphic moonlighting functions in disease.
IUBMB life 2011;63(7):489-94.
2011: Constance J Jeffery
Engineering periplasmic ligand binding proteins as glucose nanosensors.
Nano reviews 2011;2():.
2011: Céline Roux; Forum Bhatt; Johanna Foret; Benoit de Courcy; Nohad Gresh; Jean-Philip Piquemal; Constance J Jeffery; Laurent Salmon
The reaction mechanism of type I phosphomannose isomerases: new information from inhibition and polarizable molecular mechanics studies.
Proteins 2011;79(1):203-20.
2010: Forum H Bhatt; Constance J Jeffery
Expression, detergent solubilization, and purification of a membrane transporter, the MexB multidrug resistance protein.
Journal of visualized experiments : JoVE 2010;(46):.
2010: Vidya Madhavan; Forum Bhatt; Constance J Jeffery
Recombinant expression screening of P. aeruginosa bacterial inner membrane proteins.
BMC biotechnology 2010;10():83.
2009: Constance J Jeffery
Moonlighting proteins--an update.
Molecular bioSystems 2009;5(4):345-50.
2009: Diana Arsenieva; Brian L Appavu; Gloria H Mazock; Constance J Jeffery
Crystal structure of phosphoglucose isomerase from Trypanosoma brucei complexed with glucose-6-phosphate at 1.6 A resolution.
Proteins 2009;74(1):72-80.
2005: Constance J Jeffery
Mass spectrometry and the search for moonlighting proteins.
Mass spectrometry reviews 2005;24(6):772-82.
2005: Ji Hyun Lee; Constance J Jeffery
The crystal structure of rabbit phosphoglucose isomerase complexed with D-sorbitol-6-phosphate, an analog of the open chain form of D-glucose-6-phosphate.
Protein science : a publication of the Protein Society 2005;14(3):727-34.
2004: Constance J Jeffery
Molecular mechanisms for multitasking: recent crystal structures of moonlighting proteins.
Current opinion in structural biology 2004;14(6):663-8.
2004: Céline Roux; Ji Hyun Lee; Constance J Jeffery; Laurent Salmon
Inhibition of type I and type II phosphomannose isomerases by the reaction intermediate analogue 5-phospho-D-arabinonohydroxamic acid supports a catalytic role for the metal cofactor.
Biochemistry 2004;43(10):2926-34.
2003: Constance J Jeffery
Moonlighting proteins: old proteins learning new tricks.
Trends in genetics : TIG 2003;19(8):415-7.
2003: Constance J Jeffery
Multifunctional proteins: examples of gene sharing.
Annals of medicine 2003;35(1):28-35.
2002: Diana Arsenieva; Constance J Jeffery
Conformational changes in phosphoglucose isomerase induced by ligand binding.
Journal of molecular biology 2002;323(1):77-84.
2002: Diana Arsenieva; Renaud Hardré; Laurent Salmon; Constance J Jeffery
The crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonohydroxamic acid.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):5872-7.
2001: Ji Hyun Lee; K Z Chang; Vimal A Patel; Constance J Jeffery
Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate.
Biochemistry 2001;40(26):7799-805.
2001: A Pasternak; Andre White; Constance J Jeffery; N Medina; Marguerite Cahoon; Dagmar Ringe; Lizbeth Hedstrom
The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.
Protein science : a publication of the Protein Society 2001;10(7):1331-42.
2001: Constance J Jeffery; Renaud Hardré; Laurent Salmon
Crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonate identifies the role of Glu357 in catalysis.
Biochemistry 2001;40(6):1560-6.
2000: Constance J Jeffery; B J Bahnson; W Chien; Dagmar Ringe; Gregory A Petsko
Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator.
Biochemistry 2000;39(5):955-64.
2000: Constance J Jeffery; Lisa M Gloss; Gregory A Petsko; Dagmar Ringe
The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase.
Protein engineering 2000;13(2):105-12.
1999: Constance J Jeffery; Daniel E Koshland
The Escherichia coli aspartate receptor: sequence specificity of a transmembrane helix studied by hydrophobic-biased random mutagenesis.
Protein engineering 1999;12(10):863-72.
1999: Constance J Jeffery
Moonlighting proteins.
Trends in biochemical sciences 1999;24(1):8-11.
1998: Constance J Jeffery; T Barry; S Doonan; Gregory A Petsko; Dagmar Ringe
Crystallization and preliminary X-ray diffraction analysis of aspartate aminotransferase from Saccharomyces cerevisiae.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 4):659-61.
1998: Constance J Jeffery; T Barry; S Doonan; Gregory A Petsko; Dagmar Ringe
Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase.
Protein science : a publication of the Protein Society 1998;7(6):1380-7.
1994: Constance J Jeffery; Daniel E Koshland
A single hydrophobic to hydrophobic substitution in the transmembrane domain impairs aspartate receptor function.
Biochemistry 1994;33(12):3457-63.
1993: Constance J Jeffery; Daniel E Koshland
Vibrio cholerae hlyB is a member of the chemotaxis receptor gene family.
Protein science : a publication of the Protein Society 1993;2(9):1532-5.
1993: Constance J Jeffery; Daniel E Koshland
Three-dimensional structural model of the serine receptor ligand-binding domain.
Protein science : a publication of the Protein Society 1993;2(4):559-66.