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richard maser

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Hiroyuki Inuzuka; Shavali Shaik; Ichiro Onoyama; Daming Gao; Alan Tseng; richard s maser; Bo Zhai; Lixin Wan; Alejandro Gutierrez; Alan W Lau; Yonghong Xiao; Amanda L Christie; Jon Aster; Jeffrey Settleman; Steven P Gygi; Andrew L Kung; Thomas Look; Keiichi I Nakayama; Ronald A DePinho; Wenyi Wei
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Ergün Sahin; Simona Colla; Marc Liesa; Javid Moslehi; Florian L Müller; Mira Guo; Marcus Cooper; Darrell Kotton; Attila J Fabian; Carl Walkey; richard s maser; Giovanni Tonon; Friedrich Foerster; Robert Xiong; Y Alan Wang; Sachet A Shukla; Mariela Jaskelioff; Eric S Martin; Timothy P Heffernan; Alexei Protopopov; Elena Ivanova; John E Mahoney; Maria Kost-Alimova; Samuel R Perry; Roderick Bronson; Ronglih Liao; Richard Mulligan; Orian S Shirihai; Lynda Chin; Ronald A DePinho
Telomere dysfunction induces metabolic and mitochondrial compromise.
Samanthi A Perera; richard s maser; Huili Xia; Kate McNamara; Alexei Protopopov; Liang Chen; Aram F Hezel; Carla F. Kim; Roderick T Bronson; Diego H Castrillon; Lynda Chin; Nabeel Bardeesy; Ronald A DePinho; Kwok-Kin Wong
Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.

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All Publications

2011: Hiroyuki Inuzuka; Shavali Shaik; Ichiro Onoyama; Daming Gao; Alan Tseng; richard s maser; Bo Zhai; Lixin Wan; Alejandro Gutierrez; Alan W Lau; Yonghong Xiao; Amanda L Christie; Jon Aster; Jeffrey Settleman; Steven P Gygi; Andrew L Kung; Thomas Look; Keiichi I Nakayama; Ronald A DePinho; Wenyi Wei
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Nature 2011;471(7336):104-9.
2011: Ergün Sahin; Simona Colla; Marc Liesa; Javid Moslehi; Florian L Müller; Mira Guo; Marcus Cooper; Darrell Kotton; Attila J Fabian; Carl Walkey; richard s maser; Giovanni Tonon; Friedrich Foerster; Robert Xiong; Y Alan Wang; Sachet A Shukla; Mariela Jaskelioff; Eric S Martin; Timothy P Heffernan; Alexei Protopopov; Elena Ivanova; John E Mahoney; Maria Kost-Alimova; Samuel R Perry; Roderick Bronson; Ronglih Liao; Richard Mulligan; Orian S Shirihai; Lynda Chin; Ronald A DePinho
Telomere dysfunction induces metabolic and mitochondrial compromise.
Nature 2011;470(7334):359-65.
2008: Samanthi A Perera; richard s maser; Huili Xia; Kate McNamara; Alexei Protopopov; Liang Chen; Aram F Hezel; Carla F. Kim; Roderick T Bronson; Diego H Castrillon; Lynda Chin; Nabeel Bardeesy; Ronald A DePinho; Kwok-Kin Wong
Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.
Carcinogenesis 2008;29(4):747-53.
2008: Naomi M Simon; Kate McNamara; C W Chow; richard s maser; George I Papakostas; Mark H Pollack; Andrew A Nierenberg; Maurizio Fava; Kwok-Kin Wong
A detailed examination of cytokine abnormalities in Major Depressive Disorder.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(3):230-3.
2007: Jennifer O'Neil; Joëlle Tchinda; Alejandro Gutierrez; Lisa A Moreau; richard s maser; Kwok-Kin Wong; Wei Li; Keith McKenna; Xiaole (Shirley) Liu; Bin Feng; Donna Neuberg; Lewis B Silverman; Daniel J DeAngelo; Jeffery L Kutok; Rodney Rothstein; Ronald A DePinho; Lynda Chin; Charles Lee; A Thomas Look
Alu elements mediate MYB gene tandem duplication in human T-ALL.
The Journal of experimental medicine 2007;204(13):3059-66.
2007: richard s maser; Bhudipa Choudhury; Peter J Campbell; Bin Feng; Kwok-Kin Wong; Alexei Protopopov; Jennifer O'Neil; Alejandro Gutierrez; Elena Ivanova; Ilana Perna; Eric Lin; Vidya Mani; Shan Jiang; Kate McNamara; Sara Zaghlul; Sarah Edkins; Claire Stevens; Cameron Brennan; Eric S Martin; Ruprecht Wiedemeyer; Omar Kabbarah; Cristina Nogueira; Gavin Histen; Jon Aster; Marc Mansour; Veronique Duke; Letizia Foroni; Adele K Fielding; Anthony H Goldstone; Jacob M Rowe; Yaoqi A Wang; A Thomas Look; Michael R Stratton; Lynda Chin; P Andrew Futreal; Ronald A DePinho
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.
Nature 2007;447(7147):966-71.
2007: Kwok-Kin Wong; richard s maser; E Sahin; S T Bailey; Huili Xia; Hongbin Ji; Kate McNamara; M Naylor; Roderick T Bronson; S Ghosh; R Welsh; Ronald A DePinho
Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres.
Oncogene 2007;26(20):2815-21.
2007: richard s maser; Kwok-Kin Wong; Erguen Sahin; Huili Xia; Maria Naylor; H Mason Hedberg; Steven E Artandi; Ronald A DePinho
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.
Molecular and cellular biology 2007;27(6):2253-65.
2006: Naomi M Simon; Jordan W Smoller; Kate McNamara; richard s maser; Alyson K Zalta; Mark H Pollack; Andrew A Nierenberg; Maurizio Fava; Kwok-Kin Wong
Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging.
Biological psychiatry 2006;60(5):432-5.
2006: Hongbin Ji; A McGarry Houghton; T J Mariani; S Perera; Carla F. Kim; Robert F Padera; Giovanni Tonon; Kate McNamara; L A Marconcini; Aram F Hezel; N El-Bardeesy; Roderick T Bronson; D Sugarbaker; richard s maser; Steven D Shapiro; Kwok-Kin Wong
K-ras activation generates an inflammatory response in lung tumors.
Oncogene 2006;25(14):2105-12.
2005: Aram F Hezel; Nabeel Bardeesy; richard s maser
Telomere induced senescence: end game signaling.
Current molecular medicine 2005;5(2):145-52.
2004: richard s maser; Ronald A DePinho
Telomeres and the DNA damage response: why the fox is guarding the henhouse.
DNA repair 2004;3(8-9):979-88.
2003: Kwok-Kin Wong; richard s maser; Robert M Bachoo; Jayant Menon; Daniel R Carrasco; Yansong Gu; Frederick W Alt; Ronald A DePinho
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.
Nature 2003;421(6923):643-8.
2003: richard s maser; Ronald A DePinho
Take care of your chromosomes lest cancer take care of you.
Cancer cell 2003;3(1):4-6.
2003: Sandy Chang; Christine M Khoo; Maria L Naylor; richard s maser; Ronald A DePinho
Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression.
Genes & development 2003;17(1):88-100.
2002: richard s maser; Ronald A DePinho
Keeping telomerase in its place.
Nature medicine 2002;8(9):934-6.
2002: Rónán C O'Hagan; Sandy Chang; richard s maser; Ramya Mohan; Steven E Artandi; Lynda Chin; Ronald A DePinho
Telomere dysfunction provokes regional amplification and deletion in cancer genomes.
Cancer cell 2002;2(2):149-55.
2002: richard s maser; Ronald A DePinho
Connecting chromosomes, crisis, and cancer.
Science (New York, N.Y.) 2002;297(5581):565-9.
2001: K Antoku; richard s maser; W J Scully; Scott M Delach; Daniel E Johnson
Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein.
Biochemical and biophysical research communications 2001;286(5):1003-10.
2001: richard s maser; Olga K Mirzoeva; Julie Wells; HA Olivares; B R Williams; Robert A Zinkel; Peggy J Farnham; John H J Petrini
Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis.
Molecular and cellular biology 2001;21(17):6006-16.
2001: richard s maser; Robert A Zinkel; John H J Petrini
An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele.
Nature genetics 2001;27(4):417-21.
2000: richard s maser; K Antoku; W J Scully; R L Cho; Daniel E Johnson
Analysis of the role of conserved cysteine residues in the bcl-2 oncoprotein.
Biochemical and biophysical research communications 2000;277(1):171-8.
2000: Pierre-Marie Girard; Nicolas Foray; Markus Stumm; Alastair Waugh; Enriqueta Riballo; richard s maser; W P Phillips; John H J Petrini; Colin F Arlett; Penny A Jeggo
Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects.
Cancer research 2000;60(17):4881-8.
2000: Dae-Sik Lim; Seong-Tae Kim; Bo Xu; richard s maser; J Lin; John H J Petrini; Michael B Kastan
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.
Nature 2000;404(6778):613-7.
1999: Grant S Stewart; richard s maser; Tatjana Stankovic; Debra A Bressan; M I Kaplan; Nicolaas G J Jaspers; Anja Raams; Philip J Byrd; John H J Petrini; A Malcolm R Taylor
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.
Cell 1999;99(6):577-87.
1998: James P Carney; richard s maser; HA Olivares; Elizabeth M Davis; Michelle M Le Beau; John R Yates; L Hays; William F Morgan; John H J Petrini
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.
Cell 1998;93(3):477-86.
1998: Benjamin E Nelms; richard s maser; JF MacKay; M G Lagally; John H J Petrini
In situ visualization of DNA double-strand break repair in human fibroblasts.
Science (New York, N.Y.) 1998;280(5363):590-2.
1997: richard s maser; K J Monsen; Benjamin E Nelms; John H J Petrini
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.
Molecular and cellular biology 1997;17(10):6087-96.
1996: G M Dolganov; richard s maser; A Novikov; L Tosto; S Chong; Debra A Bressan; John H J Petrini
Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.
Molecular and cellular biology 1996;16(9):4832-41.