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Timothy Myers

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Yuichi Fukuda; Timothy G Myers; Huei-Fung Tsai; JOHN BENNETT
Transcriptional profiling of Candida glabrata during phagocytosis by neutrophils and in the infected mouse spleen.
Gilad Sivan; Krysia H Szymczyk; Eugen Buehler; Scott E Martin; Timothy G Myers; Pinar Ormanoglu; Bernard Moss
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.
Jason A Noble; Qin Su; Sara D Suffis; Huei-Fung Tsai; Timothy G Myers; JOHN BENNETT
STB5 is a negative regulator of azole resistance in Candida glabrata.

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2013: Yuichi Fukuda; Timothy G Myers; Huei-Fung Tsai; JOHN BENNETT
Transcriptional profiling of Candida glabrata during phagocytosis by neutrophils and in the infected mouse spleen.
Infection and immunity 2013;81(4):1325-33.
2013: Gilad Sivan; Krysia H Szymczyk; Eugen Buehler; Scott E Martin; Timothy G Myers; Pinar Ormanoglu; Bernard Moss
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(9):3519-24.
2013: Jason A Noble; Qin Su; Sara D Suffis; Huei-Fung Tsai; Timothy G Myers; JOHN BENNETT
STB5 is a negative regulator of azole resistance in Candida glabrata.
Antimicrobial agents and chemotherapy 2013;57(2):959-67.
2013: Miranda S Oakley; Phuong Thao Pham; Vivek Anantharaman; L Aravind; Yamei Gao; Noel Gerald; Leda Lotspeich-Cole; Babita Mahajan; Victoria Majam; Thomas F McCutchan; Sheldon L Morris; Timothy G Myers; Sanjai Kumar
Radiation-induced cellular and molecular alterations in asexual intraerythrocytic Plasmodium falciparum.
The Journal of infectious diseases 2013;207(1):164-74.
2012: Chia-Yen Chen; Ya-Hui Chi; Stasia A Anderson; Rafidah Abdul Mutalif; Timothy G Myers; Matthew F Starost; Colin L Stewart; Kuan-Teh Jeang
Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.
Cell 2012;149(3):565-77.
2012: Kristin L McNally; Dana Mitzel; Timothy G Myers; José M C Ribeiro; Jesus G Valenzuela; James B Wolfinbarger; Jennifer M Anderson; Sonja Best; Alvaro Godinez; Marshall E Bloom
Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection.
Ticks and tick-borne diseases 2012;3(1):18-26.
2012: Takaya Tsuno; Terry Phillips; Tongmao Zhao; Timothy G Myers; Josef Mejido; Joseph Bekisz; Kathryn C Zoon
BID is a critical factor controlling cell viability regulated by IFN-α.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012;35(1):23-31.
2011: Aleksey Novikov; Ronald L Rabin; Kevin Shenderov; Alan Sher; Robert Thompson; Giorgio Trinchieri; Marco Cardone; Kevin D Kirschman; Katrin D Mayer-Barber; Timothy G Myers; Carl G Feng
Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2540-7.
2011: Amos Adler; Yoon-Dong Park; Peter Larsen; Vijayaraj Nagarajan; Kurt Wollenberg; Jin Qiu; Timothy G Myers; Peter R Williamson
A novel specificity protein 1 (SP1)-like gene regulating protein kinase C-1 (Pkc1)-dependent cell wall integrity and virulence factors in Cryptococcus neoformans.
The Journal of biological chemistry 2011;286(23):20977-90.
2011: Miranda S Oakley; Vivek Anantharaman; Thiago M Venancio; Hong Zheng; Babita Mahajan; Victoria Majam; Thomas F McCutchan; Timothy G Myers; L Aravind; Sanjai Kumar
Molecular correlates of experimental cerebral malaria detectable in whole blood.
Infection and immunity 2011;79(3):1244-53.
2011: B Rada; P Gardina; Timothy G Myers; Thomas L Leto
Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin.
Mucosal immunology 2011;4(2):158-71.
2011: Roshan Ramanathan; Sudhir Varma; José M C Ribeiro; Timothy G Myers; Thomas Nolan; David Abraham; James B Lok; Thomas B Nutman
Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis.
PLoS neglected tropical diseases 2011;5(5):e1039.
2010: Claro Yu; Denali Boon; Shannon L McDonald; Timothy G Myers; Keiko Tomioka; Hanh Nguyen; Ronald E Engle; Sugantha Govindarajan; Suzanne U Emerson; Robert H Purcell
Pathogenesis of hepatitis E virus and hepatitis C virus in chimpanzees: similarities and differences.
Journal of virology 2010;84(21):11264-78.
2010: Huei-Fung Tsai; Lindsay R Sammons; Xiaozhen Zhang; Sara D Suffis; Qin Su; Timothy G Myers; Kieren Marr; JOHN BENNETT
Microarray and molecular analyses of the azole resistance mechanism in Candida glabrata oropharyngeal isolates.
Antimicrobial agents and chemotherapy 2010;54(8):3308-17.
2008: Shen Luo; Megan McNeill; Timothy G Myers; Robert J Hohman; Rodney L Levine
Lon protease promotes survival of Escherichia coli during anaerobic glucose starvation.
Archives of microbiology 2008;189(2):181-5.
2005: Marietjie Venter; Timothy G Myers; Michael A Wilson; Thomas J Kindt; Janusz T Paweska; Felicity J Burt; Patricia A Leman; Robert Swanepoel
Gene expression in mice infected with West Nile virus strains of different neurovirulence.
Virology 2005;342(1):119-40.
2005: Man Lung Yeung; Yamina Bennasser; Timothy G Myers; Guojian Jiang; Monsef Benkirane; Kuan-Teh Jeang
Changes in microRNA expression profiles in HIV-1-transfected human cells.
Retrovirology 2005;2():81.
2005: Christopher J Schaupp; Guojian Jiang; Timothy G Myers; Michael A Wilson
Active mixing during hybridization improves the accuracy and reproducibility of microarray results.
BioTechniques 2005;38(1):117-9.
2005: Tito Fojo; Nick Farrell; Waldo Ortuzar; Hideyuki Tanimura; John Weinstein; Timothy G Myers
Identification of non-cross-resistant platinum compounds with novel cytotoxicity profiles using the NCI anticancer drug screen and clustered image map visualizations.
Critical reviews in oncology/hematology 2005;53(1):25-34.
2004: Geumsoo Kim; Tae-Hoon Lee; Petra Wetzel; Cornelia Geers; Mary Ann Robinson; Timothy G Myers; Jennie W Owens; Nancy B Wehr; Michael W Eckhaus; Gerolf Gros; Anthony Wynshaw-Boris; Rodney L Levine
Carbonic anhydrase III is not required in the mouse for normal growth, development, and life span.
Molecular and cellular biology 2004;24(22):9942-7.
2004: Helena I Boshoff; Timothy G Myers; Brent Copp; Michael R McNeil; Michael A Wilson; Clifton E Barry
The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.
The Journal of biological chemistry 2004;279(38):40174-84.
2004: Susan D Mertins; Timothy G Myers; Susan Holbeck; Wilma Medina-Perez; Elaine Wang; Glenda Kohlhagen; Yves Pommier; Susan E Bates
In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity.
Molecular cancer therapeutics 2004;3(7):849-60.
2002: Zhiyuan Xu; Zhong-Ping Chen; Areti Malapetsa; Moulay A Alaoui-Jamali; Josée Bergeron; Anne Monks; Timothy G Myers; Gérard Mohr; Edward A Sausville; Dominic A Scudiero; Raquel Aloyz; Lawrence Panasci
DNA repair protein levels vis-à-vis anticancer drug resistance in the human tumor cell lines of the National Cancer Institute drug screening program.
Anti-cancer drugs 2002;13(5):511-9.
2002: Zhong-Ping Chen; Areti Malapetsa; Anne Monks; Timothy G Myers; Gérard Mohr; Edward A Sausville; Dominic A Scudiero; Lawrence Panasci
Nucleotide excision repair protein levels vis-à-vis anticancer drug resistance in 60 human tumor cell lines.
Ai zheng = Aizheng = Chinese journal of cancer 2002;21(3):233-9.
2001: Allyson L Parr; Timothy G Myers; Susan Holbeck; Y J Loh; Carmen J Allegra
Thymidylate synthase as a molecular target for drug discovery using the National Cancer Institute's Anticancer Drug Screen.
Anti-cancer drugs 2001;12(7):569-74.
2001: Susan D Mertins; Timothy G Myers; Melinda G Hollingshead; D Dykes; E Bodde; P Tsai; C A Jefferis; R Gupta; W Marston Linehan; Michael C Alley; Susan E Bates
Screening for and identification of novel agents directed at renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):620-33.
2001: M I Nicoletti; Timothy G Myers; Tito Fojo; Mikhail V Blagosklonny
Wild-type p53 marginally induces endogenous MDR-1 mRNA without causing a measurable drug resistance in human cancer cells.
International journal of oncology 2001;18(2):375-81.
2000: Sally A Amundson; Timothy G Myers; Dominic A Scudiero; Shinichi Kitada; J C Reed; Albert J Fornace
An informatics approach identifying markers of chemosensitivity in human cancer cell lines.
Cancer research 2000;60(21):6101-10.
2000: Uwe Scherf; Douglas T Ross; Mark Waltham; Lawrence H Smith; Jae K Lee; Lorraine Tanabe; Kurt W Kohn; William C Reinhold; Timothy G Myers; D T Andrews; Dominic A Scudiero; Michael B Eisen; Edward A Sausville; Yves Pommier; David Botstein; Patrick O Brown; John N Weinstein
A gene expression database for the molecular pharmacology of cancer.
Nature genetics 2000;24(3):236-44.
2000: Douglas T Ross; Uwe Scherf; Michael B Eisen; Charles M Perou; C Rees; Paul Spellman; V Iyer; Stefanie S Jeffrey; Matt van de Rijn; Mark Waltham; A Pergamenschikov; JC Lee; DA Lashkari; D Shalon; Timothy G Myers; John N Weinstein; David Botstein; Patrick O Brown
Systematic variation in gene expression patterns in human cancer cell lines.
Nature genetics 2000;24(3):227-35.
2000: W W van Osdol; Timothy G Myers; J N Weinstein
Neural network techniques for informatics of cancer drug discovery.
Methods in enzymology 2000;321():369-95.
1999: Lloyd R Kelland; SY Sharp; Paul M Rogers; Timothy G Myers; Paul Workman
DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90.
Journal of the National Cancer Institute 1999;91(22):1940-9.
1999: France Carrier; Philippe Georgel; Philippe Pourquier; Mellissa Blake; H Udo Kontny; Michael J Antinore; M Gariboldi; Timothy G Myers; John N Weinstein; Yves Pommier; Albert J Fornace
Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin.
Molecular and cellular biology 1999;19(3):1673-85.
1999: Albert J Fornace; Sally A Amundson; Michael Bittner; Timothy G Myers; Paul Meltzer; J N Weinsten; Jeffrey M. Trent
The complexity of radiation stress responses: analysis by informatics and functional genomics approaches.
Gene expression 1999;7(4-6):387-400.
1998: Sally A Amundson; Timothy G Myers; Albert J Fornace
Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress.
Oncogene 1998;17(25):3287-99.
1998: Jonathan R Dimmock; NM Kandepu; M Hetherington; J Wilson Quail; U Pugazhenthi; Athena Sudom; Mahmood Chamankhah; P Rose; E Pass; Theresa M Allen; S Halleran; J Szydlowski; Bulent Mutus; M Tannous; Elias K Manavathu; Timothy G Myers; Erik De Clercq; Jan Balzarini
Cytotoxic activities of Mannich bases of chalcones and related compounds.
Journal of medicinal chemistry 1998;41(7):1014-26.
1998: Leming Shi; Y Fan; Timothy G Myers; Patrick M O'Connor; KD Paull; SH Friend; John N Weinstein
Mining the NCI anticancer drug discovery databases: genetic function approximation for the QSAR study of anticancer ellipticine analogues.
Journal of chemical information and computer sciences 1998;38(2):189-99.
1998: Leming Shi; Timothy G Myers; Y Fan; Patrick M O'Connor; KD Paull; SH Friend; John N Weinstein
Mining the National Cancer Institute Anticancer Drug Discovery Database: cluster analysis of ellipticine analogs with p53-inverse and central nervous system-selective patterns of activity.
Molecular pharmacology 1998;53(2):241-51.
1998: Shinichi Kitada; Maryla Krajewska; X Zhang; Dominic A Scudiero; Juan M Zapata; Hong-Gang Wang; Ahmed Shabaik; G Tudor; Stan Krajewski; Timothy G Myers; G S Johnson; Edward A Sausville; John C Reed
Expression and location of pro-apoptotic Bcl-2 family protein BAD in normal human tissues and tumor cell lines.
The American journal of pathology 1998;152(1):51-61.
1997: K Wosikowski; D Schuurhuis; K Johnson; KD Paull; Timothy G Myers; John N Weinstein; Susan E Bates
Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns.
Journal of the National Cancer Institute 1997;89(20):1505-15.
1997: Patrick M O'Connor; J Jackman; I Bae; Timothy G Myers; S Fan; Michihiro Mutoh; Dominic A Scudiero; Anne Monks; Edward A Sausville; John N Weinstein; SH Friend; Albert J Fornace; Kurt W Kohn
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.
Cancer research 1997;57(19):4285-300.
1997: Jeffrey A Moscow; T Connolly; Timothy G Myers; C C Cheng; KD Paull; Kenneth H Cowan
Reduced folate carrier gene (RFC1) expression and anti-folate resistance in transfected and non-selected cell lines.
International journal of cancer. Journal international du cancer 1997;72(1):184-90.
1997: Timothy G Myers; N L Anderson; Mark Waltham; Guang Li; JK Buolamwini; Dominic A Scudiero; KD Paull; Edward A Sausville; John N Weinstein
A protein expression database for the molecular pharmacology of cancer.
Electrophoresis 1997;18(3-4):647-53.
1997: J N Weinstein; Timothy G Myers; P M O'Connor; S H Friend; Albert J Fornace; K W Kohn; T Fojo; S E Bates; L V Rubinstein; N L Anderson; JK Buolamwini; W W van Osdol; Anne Monks; Dominic A Scudiero; Edward A Sausville; Daniel W Zaharevitz; B Bunow; Vellarkad Viswanadhan; G S Johnson; R E Wittes; KD Paull
An information-intensive approach to the molecular pharmacology of cancer.
Science (New York, N.Y.) 1997;275(5298):343-9.
1995: Timothy G Myers; E C Dietz; N L Anderson; E A Khairallah; S D Cohen; Sidney D Nelson
A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3'-hydroxyacetanilide.
Chemical research in toxicology 1995;8(3):403-13.
1995: Susan E Bates; A T Fojo; John N Weinstein; Timothy G Myers; M Alvarez; K D Pauli; B A Chabner
Molecular targets in the National Cancer Institute drug screen.
Journal of cancer research and clinical oncology 1995;121(9-10):495-500.
1994: W W van Osdol; Timothy G Myers; KD Paull; Kurt W Kohn; John N Weinstein
Use of the Kohonen self-organizing map to study the mechanisms of action of chemotherapeutic agents.
Journal of the National Cancer Institute 1994;86(24):1853-9.
1994: S J Hargus; H R Amouzedeh; N R Pumford; Timothy G Myers; S C McCoy; Lance R Pohl
Metabolic activation and immunochemical localization of liver protein adducts of the nonsteroidal anti-inflammatory drug diclofenac.
Chemical research in toxicology 1994;7(4):575-82.
1994: Timothy G Myers; Kenneth E Thummel; Thomas F Kalhorn; Sidney D Nelson
Preferred orientations in the binding of 4'-hydroxyacetanilide (acetaminophen) to cytochrome P450 1A1 and 2B1 isoforms as determined by 13C- and 15N-NMR relaxation studies.
Journal of medicinal chemistry 1994;37(6):860-7.
1994: John N Weinstein; Timothy G Myers; J Buolamwini; K Raghavan; W van Osdol; J Licht; Vellarkad Viswanadhan; Kurt W Kohn; L V Rubinstein; A D Koutsoukos
Predictive statistics and artificial intelligence in the U.S. National Cancer Institute's Drug Discovery Program for Cancer and AIDS.
Stem cells (Dayton, Ohio) 1994;12(1):13-22.
1993: N R Pumford; Timothy G Myers; J C Davila; R J Highet; Lance R Pohl
Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac.
Chemical research in toxicology 1993;6(2):147-50.
1991: Sidney D Nelson; M A Tirmenstein; M S Rashed; Timothy G Myers
Acetaminophen and protein thiol modification.
Advances in experimental medicine and biology 1991;283():579-88.
1990: P G Pearson; James G. Omichinski; Timothy G Myers; Erik J Søderlund; Erik Dybing; Sidney D Nelson
Metabolic activation of 1,2-dibromo-3-chloropropane to mutagenic metabolites: detection and mechanism of formation of (Z)- and (E)-2-chloro-3-(bromomethyl)oxirane.
Chemical research in toxicology 1990;3(5):458-66.
1990: M S Rashed; Timothy G Myers; Sidney D Nelson
Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(5):765-70.
1990: Timothy G Myers; Sidney D Nelson
Neuroactive carbamate adducts of beta-N-methylamino-L-alanine and ethylenediamine. Detection and quantitation under physiological conditions by 13C NMR.
The Journal of biological chemistry 1990;265(18):10193-5.
1987: M I Fatehi; DZ Gerhart; Timothy G Myers; Lester Drewes
Characterization of the blood-brain barrier: glycoconjugate receptors of 14 lectins in canine brain, cultured endothelial cells, and blotted membrane proteins.
Brain research 1987;415(1):30-9.