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Samuel achilefu

Research Profile

Chemicals & Drugs

Procedures

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Anatomy

Tumor Cell Line

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Tissue Distribution

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Fluorescence

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TOP 3
Zhenghui Wang; Karen L Wooley; Ke Zhang; Samuel achilefu; Sharon Bloch; Yuefei Shen; Jillian Smith; John-Stephen Taylor
Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles.
Duanwen Shen; Rui Tang; Baogang Xu; Mingfeng Bai; Xiaoming Ju; Richard G Pestell; Samuel achilefu
Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity.
Yang Liu; Suman Mondal; Gail P Sudlow; Walter J Akers; Adam Q Bauer; Joseph P Culver; Kyle Gullicksrud; Samuel achilefu
Intraoperative detection of liver tumors aided by a fluorescence goggle system and multimodal imaging.

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All Publications

2013: Zhenghui Wang; Karen L Wooley; Ke Zhang; Samuel achilefu; Sharon Bloch; Yuefei Shen; Jillian Smith; John-Stephen Taylor
Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles.
Organic & biomolecular chemistry 2013;11(19):3159-67.
2013: Duanwen Shen; Rui Tang; Baogang Xu; Mingfeng Bai; Xiaoming Ju; Richard G Pestell; Samuel achilefu
Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity.
Scientific reports 2013;3():1697.
2013: Yang Liu; Suman Mondal; Gail P Sudlow; Walter J Akers; Adam Q Bauer; Joseph P Culver; Kyle Gullicksrud; Samuel achilefu
Intraoperative detection of liver tumors aided by a fluorescence goggle system and multimodal imaging.
The Analyst 2013;138(8):2254-7.
2013: Dawei Deng; Samuel achilefu; Jie Cao; Lingzhi Qu; Yueqing Gu
Highly luminescent water-soluble quaternary Zn-Ag-In-S quantum dots for tumor cell-targeted imaging.
Physical chemistry chemical physics : PCCP 2013;15(14):5078-83.
2013: Metasebya Solomon; Gail P Suddlow; Yuan-Chuan Tai; Baogang Xu; Hamid Deghani; WB Edwards; Adam T Eggebrecht; Kexian Liang; Ralph E Nothdruft; Samuel achilefu; Akers Walter; Joseph P Culver
Multimodal fluorescence-mediated tomography and SPECT/CT for small-animal imaging.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013;54(4):639-46.
2013: Changli Du; Samuel achilefu; Jie Cao; Dawei Deng; Lingling Shan; Junmei Tian; Shunan Wan; Yueqing Gu
A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery.
Biomaterials 2013;34(12):3087-97.
2013: Jianpeng Xue; Hongyan Zhu; Yang Li; Zhiyu Qian; Lingling Shan; Samuel achilefu; Haiyan Chen; Dawei Deng; Yueqing Gu
Visual detection of STAT5B gene expression in living cell using the hairpin DNA modified gold nanoparticle beacon.
Biosensors & bioelectronics 2013;41():71-7.
2013: Xiaoxiao Xu; Pinaki Sarder; Samuel achilefu; Nalinikanth Kotagiri; Arye Nehorai
Performance analysis and design of position-encoded microsphere arrays using the Ziv-Zakai bound.
IEEE transactions on nanobioscience 2013;12(1):29-40.
2013: Hyeran Lee; Rui Tang; Natalia Zhegalova; Mikhail Y Berezin; Samuel achilefu
Pyrazole-substituted near-infrared cyanine dyes exhibit pH-dependent fluorescence lifetime properties.
Photochemistry and photobiology 2013;89(2):326-31.
2013: Sisi Cui; Yingfeng Di; Samuel achilefu; Haiyan Chen; Yuqi Chen; Yuxiang Ma; Deyan Yin; Yueqing Gu
In vivo targeted deep-tissue photodynamic therapy based on near-infrared light triggered upconversion nanoconstruct.
ACS nano 2013;7(1):676-88.
2013: Yang Liu; Metasebya Solomon; Samuel achilefu
Perspectives and potential applications of nanomedicine in breast and prostate cancer.
Medicinal research reviews 2013;33(1):3-32.
2013: Jianting Wang; Damon Wheeler; Jin Z Zhang; Samuel achilefu; Kyung A Kang
NIR fluorophore-hollow gold nanosphere complex for cancer enzyme-triggered detection and hyperthermia.
Advances in experimental medicine and biology 2013;765():323-8.
2012: Shaw-Wei D Tsen; Kong-Thon Tsen; Dong Yu; Wandy Beatty; Travis Chapa; Samuel achilefu
Inactivation of enveloped virus by laser-driven protein aggregation.
Journal of biomedical optics 2012;17(12):128002.
2012: Jeffrey C Gildersleeve; Zhude Tu; Baomei Wang; Samuel achilefu; Mai Xu
Glycan array analysis of the antigen repertoire targeted by tumor-binding antibodies.
Bioorganic & medicinal chemistry letters 2012;22(22):6839-43.
2012: Yang Liu; Gail Sudlow; Timothy York; Walter Akers; Viktor Gruev; Samuel achilefu
Complementary fluorescence-polarization microscopy using division-of-focal-plane polarization imaging sensor.
Journal of biomedical optics 2012;17(11):116001.
2012: Haiyan Chen; Sisi Cui; Yueqing Gu; Bowen Li; Shulan Li; Shengnan Li; Didel M Mahounga; Xueyan Ren; Samuel achilefu
Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy.
Nanoscale 2012;4(19):6050-64.
2012: M Xu; W J Akers; D Cao; J F DiPersio; D G Mutch; M P Rettig; G Sudlow; B Wang; Samuel achilefu
Preclinical evaluation of Mab CC188 for ovarian cancer imaging.
International journal of cancer. Journal international du cancer 2012;131(6):1351-9.
2012: Yunpeng Ye; Walter Akers; Sharon Bloch; Charles Odonkor; Baogang Xu; Samuel achilefu
Near-infrared fluorescent divalent RGD ligand for integrin αvβ₃-targeted optical imaging.
Bioorganic & medicinal chemistry letters 2012;22(17):5405-9.
2012: Samuel achilefu
Rapid response activatable molecular probes for intraoperative optical image-guided tumor resection.
Hepatology (Baltimore, Md.) 2012;56(3):1170-3.
2012: R Nothdurft; P Sarder; S Bloch; J Culver; Samuel achilefu
Fluorescence lifetime imaging microscopy using near-infrared contrast agents.
Journal of microscopy 2012;247(2):202-7.
2012: Alexandru V Korotcov; Stephen Lin; Rajagopalan Sridhar; Samuel achilefu; Yue Chen; Sophia Huang; Yunpeng Ye; Fayun Zhang; Paul C Wang
Glucosamine-linked near-infrared fluorescent probes for imaging of solid tumor xenografts.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2012;14(4):443-51.
2012: Hui Li; Zhiyu Qian; Zhenzhen Tu; Samuel achilefu; Lianxiao An; Yueqing Gu
Inhibitory effects of ERβ on proliferation, invasion, and tumor formation of MCF-7 breast cancer cells--prognostication for the use of ERβ-selective therapy.
Pharmaceutical biology 2012;50(7):839-49.
2012: Zhenzhen Tu; Samuel achilefu; Walter Akers; Hui Li; Yuxiang Ma; Bin Tang; Junmei Tian; Yueqing Gu
The enhanced antiproliferative response to combined treatment of trichostatin A with raloxifene in MCF-7 breast cancer cells and its relevance to estrogen receptor β expression.
Molecular and cellular biochemistry 2012;366(1-2):111-22.
2012: Zhenzhen Tu; Samuel achilefu; Walter Akers; Hui Li; Yuxiang Ma; Junmei Tian; Yueqing Gu
Estrogen receptor β potentiates the antiproliferative effect of raloxifene and affects the cell migration and invasion in HCT-116 colon cancer cells.
Journal of cancer research and clinical oncology 2012;138(7):1091-103.
2012: Jeffrey M Craft; Ravindra A De Silva; Kimberly A Lears; Kexian Liang; Samuel achilefu; Rebecca Andrews; Buck E Rogers
In vitro and in vivo evaluation of a 64Cu-labeled NOTA-Bn-SCN-Aoc-bombesin analogue in gastrin-releasing peptide receptor expressing prostate cancer.
Nuclear medicine and biology 2012;39(5):609-16.
2012: Jing Guo; Zhiyu Qian; Lingling Shan; Bing Xue; Hongyan Zhu; Samuel achilefu; Changli Du; Yueqing Gu
Comparison of near-infrared fluorescent deoxyglucose probes with different dyes for tumor diagnosis in vivo.
Contrast media & molecular imaging 2012;7(3):289-301.
2012: Bing Xue; Xin Li; Fei Liu; Samuel achilefu; Akers Walter; Jie Cao; Da-Wei Deng; Yue-Qing Gu
Synthesis of NAC capped near infrared-emitting CdTeS alloyed quantum dots and application for in vivo early tumor imaging.
Dalton transactions (Cambridge, England : 2003) 2012;41(16):4935-47.
2012: Xuan Zhang; Akers Walter; Sharon Bloch; Samuel achilefu
Near-infrared molecular probes for in vivo imaging.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2012;Chapter 12():Unit12.27.
2012: Akers Walter; Samuel achilefu; Gregg B Fields; Hyeran Lee; Gail P Sudlow; Baogang Xu; WB Edwards
Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe.
Bioconjugate chemistry 2012;23(3):656-63.
2012: Rui Tang; Hyeran Lee; Samuel achilefu
Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes.
Journal of the American Chemical Society 2012;134(10):4545-8.
2012: Jianting Wang; Samuel achilefu; Sebastien Laulhe; Joseph Moore; Michael Nantz; Kyung A Kang
Fluorophore-gold nanoparticle complex for sensitive optical biosensing and imaging.
Nanotechnology 2012;23(9):095501.
2012: Akers Walter; WB Edwards; Todd N Erpelding; Chulhong Kim; Lihong V Wang; Baogang Xu; Samuel achilefu
Multimodal sentinel lymph node mapping with single-photon emission computed tomography (SPECT)/computed tomography (CT) and photoacoustic tomography.
Translational research : the journal of laboratory and clinical medicine 2012;159(3):175-81.
2012: Tiffany P Gustafson; Qian Cao; Samuel achilefu; Mikhail Y Berezin
Defining a polymethine dye for fluorescence anisotropy applications in the near-infrared spectral range.
Chemphyschem : a European journal of chemical physics and physical chemistry 2012;13(3):716-23.
2012: Kevin Guo; Samuel achilefu; Mikhail Y Berezin
Dating bloodstains with fluorescence lifetime measurements.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(5):1303-5.
2012: Yasaman Ardeshirpour; Jacek Capala; Victor Chernomordik; Amir H Gandjbakhche; Gary Griffiths; Jay R Knutson; Ilya Lyakhov; Aleksandr V Smirnov; Olga Vasalatiy; Rafal Zielinski; Samuel achilefu; Moinuddin Hassan
In vivo fluorescence lifetime imaging monitors binding of specific probes to cancer biomarkers.
PloS one 2012;7(2):e31881.
2012: Kyung A Kang; Sebastien Laulhe; Joseph D Moore; Michael Nantz; Martin G O'Toole; Jianting Wang; Samuel achilefu
Sensitivity enhancement of NIR fluorescence contrast agent utilizing gold nanoparticles.
Advances in experimental medicine and biology 2012;737():285-91.
2012: Lingling Shan; Shunan Wan; Zhiyu Qian; Samuel achilefu; Sisi Cui; Changli Du; Yueqing Gu
A paclitaxel-conjugated adenovirus vector for targeted drug delivery for tumor therapy.
Biomaterials 2012;33(1):146-62.
2011: Metasebya Solomon; Akers Walter; Samuel achilefu; Adam T Eggebrecht; Ralph E Nothdruft; Gail Sudlow; Brian R White; Joseph P Culver
Video-rate fluorescence diffuse optical tomography for in vivo sentinel lymph node imaging.
Biomedical optics express 2011;2(12):3267-77.
2011: Y Ardeshirpour; Jacek Capala; Victor Chernomordik; G Griffiths; M Hassan; P Smith; R Zielinsky; Samuel achilefu; Amir H Gandjbakhche
Using in-vivo fluorescence imaging in personalized cancer diagnostics and therapy, an image and treat paradigm.
Technology in cancer research & treatment 2011;10(6):549-60.
2011: Y Pu; M Sharanov; G C Tang; W B Wang; Min Xu; Samuel achilefu; Y Budansky; J A Eastham; Robert R Alfano
Near infrared photonic finger imager for prostate cancer screening.
Technology in cancer research & treatment 2011;10(6):507-17.
2011: Mikhail Y Berezin; Chulmin Joo; Hyeran Lee; Siavash Yazdanfar; Chun Zhan; Akers Walter; Samuel achilefu
Two-photon optical properties of near-infrared dyes at 1.55 μm excitation.
The journal of physical chemistry. B 2011;115(39):11530-5.
2011: Jianting Wang; Samuel achilefu; Michael Nantz; Kyung A Kang
Gold nanoparticle-fluorophore complex for conditionally fluorescing signal mediator.
Analytica chimica acta 2011;695(1-2):96-104.
2011: Metasebya Solomon; Gail P Sudlow; Samuel achilefu; Mikhail Berezin; WB Edwards; Kevin Guo; Akers Walter
Detection of enzyme activity in orthotopic murine breast cancer by fluorescence lifetime imaging using a fluorescence resonance energy transfer-based molecular probe.
Journal of biomedical optics 2011;16(6):066019.
2011: Yang Liu; Adam Q Bauer; Akers Walter; Gail Sudlow; Kexian Liang; Duanwen Shen; Mikhail Y Berezin; Joseph P Culver; Samuel achilefu
Hands-free, wireless goggles for near-infrared fluorescence and real-time image-guided surgery.
Surgery 2011;149(5):689-98.
2011: Mikhail Berezin; Kevin Guo; Akers Walter; Ralph E Northdurft; Joseph P Culver; Bao Teng; Olga Vasalatiy; Kyle Barbacow; Amir H Gandjbakhche; Gary L Griffiths; Samuel achilefu
Near-infrared fluorescence lifetime pH-sensitive probes.
Biophysical journal 2011;100(8):2063-72.
2011: Lingling Shan; Jianpeng Xue; Jing Guo; Zhiyu Qian; Samuel achilefu; Yueqing Gu
Improved targeting of ligand-modified adenovirus as a new near infrared fluorescence tumor imaging probe.
Bioconjugate chemistry 2011;22(4):567-81.
2011: Hyeran Lee; Akers Walter; Kumar Bhushan; Sharon Bloch; Gail Sudlow; Rui Tang; Samuel achilefu
Near-infrared pH-activatable fluorescent probes for imaging primary and metastatic breast tumors.
Bioconjugate chemistry 2011;22(4):777-84.
2011: Mikhail Berezin; Kevin Guo; Akers Walter; Joseph Livingston; Metasebya Solomon; Hyeran Lee; Kexian Liang; Anthony Agee; Samuel achilefu
Rational approach to select small peptide molecular probes labeled with fluorescent cyanine dyes for in vivo optical imaging.
Biochemistry 2011;50(13):2691-700.
2011: Yang Pu; Wubao B Wang; Samuel achilefu; R R Alfano
Study of rotational dynamics of receptor-targeted contrast agents in cancerous and normal prostate tissues using time-resolved picosecond emission spectroscopy.
Applied optics 2011;50(10):1312-22.
2011: Yunpeng Ye; Baogang Xu; Gregory V Nikiforovich; Sharon Bloch; Samuel achilefu
Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging.
Bioorganic & medicinal chemistry letters 2011;21(7):2116-20.
2011: Weiyang Li; Xin Cai; Chulhong Kim; Guorong Sun; Yu Zhang; Rui Deng; Miaoxin Yang; Jingyi Chen; Samuel achilefu; Lihong V Wang; Younan Xia
Gold nanocages covered with thermally-responsive polymers for controlled release by high-intensity focused ultrasound.
Nanoscale 2011;3(4):1724-30.
2011: Kimberly A Lears; Riccardo Ferdani; Kexian Liang; Alexander Zheleznyak; Rebecca Andrews; Christopher D Sherman; Samuel achilefu; Carolyn J Anderson; Buck E Rogers
In vitro and in vivo evaluation of 64Cu-labeled SarAr-bombesin analogs in gastrin-releasing peptide receptor-expressing prostate cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(3):470-7.
2011: Akers Walter; Chulhong Kim; Mikhail Berezin; Kevin Guo; Ralph Fuhrhop; Gregory M Lanza; Georg M Fischer; Ewald Daltrozzo; Andreas Zumbusch; Xin Cai; Lihong V Wang; Samuel achilefu
Noninvasive photoacoustic and fluorescence sentinel lymph node identification using dye-loaded perfluorocarbon nanoparticles.
ACS nano 2011;5(1):173-82.
2011: Metasebya Solomon; Mikhail Y Berezin; Yang Liu; Samuel achilefu
Optical imaging in cancer research: basic principles, tumor detection, and therapeutic monitoring.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2011;20(5):397-415.
2011: Kyung A Kang; Jianting Wang; Jacek B Jasinski; Samuel achilefu
Fluorescence manipulation by gold nanoparticles: from complete quenching to extensive enhancement.
Journal of nanobiotechnology 2011;9():16.
2011: Jianting Wang; Martin O'Toole; Archna Massey; Souvik Biswas; Michael Nantz; Samuel achilefu; Kyung A Kang
Highly specific, NIR fluorescent contrast agent with emission controlled by gold nanoparticle.
Advances in experimental medicine and biology 2011;701():149-54.
2011: Mingfeng Bai; Samuel achilefu
Synthesis and spectroscopy of near infrared fluorescent dyes for investigating dichromic fluorescence.
Bioorganic & medicinal chemistry letters 2011;21(1):280-4.
2010: Samuel achilefu
The insatiable quest for near-infrared fluorescent probes for molecular imaging.
Angewandte Chemie (International ed. in English) 2010;49(51):9816-8.
2010: Fei Liu; Dawei Deng; Xinyang Chen; Zhiyu Qian; Samuel achilefu; Yueqing Gu
Folate-polyethylene glycol conjugated near-infrared fluorescence probe with high targeting affinity and sensitivity for in vivo early tumor diagnosis.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(6):595-607.
2010: Tzu-Chen Yen; Shiaw-Pyng Wey; Chang-Hui Liao; Chi-Hsiao Yeh; Duan-Wen Shen; Samuel achilefu; Tze-Chein Wun
Measurement of the binding parameters of annexin derivative-erythrocyte membrane interactions.
Analytical biochemistry 2010;406(1):70-9.
2010: Ron Chen; Jesse J Parry; Akers Walter; Mikhail Berezin; Issam El-Naqa; Samuel achilefu; WB Edwards; Buck E Rogers
Multimodality imaging of gene transfer with a receptor-based reporter gene.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1456-63.
2010: Mai Xu; Fan Wang; Jeffrey C Gildersleeve; Samuel achilefu
MAb L9E10 to blood group H2 antigen binds to colon cancer stem cells and inhibits tumor cell migration and invasion.
Hybridoma (2005) 2010;29(4):355-9.
2010: Chulhong Kim; Todd N Erpelding; Konstantin Maslov; Ladislav Jankovic; Akers Walter; Liang Song; Samuel achilefu; Julie A Margenthaler; Michael D Pashley; Lihong V Wang
Handheld array-based photoacoustic probe for guiding needle biopsy of sentinel lymph nodes.
Journal of biomedical optics 2010;15(4):046010.
2010: Akers Walter; Zongren Zhang; Mikhail Berezin; Yunpeng Ye; Anthony Agee; Kevin Guo; Ralph W Fuhrhop; Samuel A Wickline; Gregory M Lanza; Samuel achilefu
Targeting of alpha(nu)beta(3)-integrins expressed on tumor tissue and neovasculature using fluorescent small molecules and nanoparticles.
Nanomedicine (London, England) 2010;5(5):715-26.
2010: Kevin Guo; Mikhail Y Berezin; Jie Zheng; Akers Walter; Franck Lin; Bao Teng; Olga Vasalatiy; Amir Gandjbakhche; Gary L Griffiths; Samuel achilefu
Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging.
Chemical communications (Cambridge, England) 2010;46(21):3705-7.
2010: Samuel achilefu
Introduction to concepts and strategies for molecular imaging.
Chemical reviews 2010;110(5):2575-8.
2010: Mikhail Y Berezin; Samuel achilefu
Fluorescence lifetime measurements and biological imaging.
Chemical reviews 2010;110(5):2641-84.
2010: Siavash Yazdanfar; Chulmin Joo; Chun Zhan; Mikhail Y Berezin; Akers Walter; Samuel achilefu
Multiphoton microscopy with near infrared contrast agents.
Journal of biomedical optics 2010;15(3):030505.
2010: Guorong Sun; Mikhail Y Berezin; Jinda Fan; Hyeran Lee; Jun Ma; Ke Zhang; Karen L Wooley; Samuel achilefu
Bright fluorescent nanoparticles for developing potential optical imaging contrast agents.
Nanoscale 2010;2(4):548-58.
2010: Bryan A Smith; Akers Walter; W Matthew Leevy; Andrew J Lampkins; Shuzhang Xiao; William Wolter; Mark A Suckow; Samuel achilefu; Bradley D Smith
Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces.
Journal of the American Chemical Society 2010;132(1):67-9.
2010: Jianting Wang; Michael H Nantz; Samuel achilefu; Kyung A Kang
FRET-like fluorophore-nanoparticle complex for highly specific cancer localization.
Advances in experimental medicine and biology 2010;662():407-13.
2009: Mikhail Berezin; Akers Walter; Kevin Guo; Georg M Fischer; Ewald Daltrozzo; Andreas Zumbusch; Samuel achilefu
Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging.
Biophysical journal 2009;97(9):L22-4.
2009: Mikhail Berezin; Kevin Guo; Bao Teng; WB Edwards; Carolyn J Anderson; Olga Vasalatiy; Amir Gandjbakhche; Gary L Griffiths; Samuel achilefu
Radioactivity-synchronized fluorescence enhancement using a radionuclide fluorescence-quenched dye.
Journal of the American Chemical Society 2009;131(26):9198-200.
2009: Hyeran Lee; Akers Walter; Philip P Cheney; WB Edwards; Kexian Liang; Joseph P Culver; Samuel achilefu
Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe.
Journal of biomedical optics 2009;14(4):040507.
2009: Charles A Odonkor; Samuel achilefu
Modulation of effector caspase cleavage determines response of breast and lung tumor cell lines to chemotherapy.
Cancer investigation 2009;27(4):417-29.
2009: Lihui Wei; Yunpeng Ye; Thaddeus J Wadas; Jason S Lewis; Michael J Welch; Samuel achilefu; Carolyn J Anderson
(64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity.
Nuclear medicine and biology 2009;36(3):277-85.
2009: Zongren Zhang; Jinda Fan; Philip P Cheney; Mikhail Berezin; WB Edwards; Akers Walter; Duanwen Shen; Kexian Liang; Joseph P Culver; Samuel achilefu
Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo.
Molecular pharmaceutics 2009;6(2):416-27.
2009: Ralph E Nothdurft; Sachin V Patwardhan; Akers Walter; Yunpeng Ye; Samuel achilefu; Joseph P Culver
In vivo fluorescence lifetime tomography.
Journal of biomedical optics 2009;14(2):024004.
2009: Reece Goiffon; Akers Walter; Mikhail Y Berezin; Hyeran Lee; Samuel achilefu
Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging.
Journal of biomedical optics 2009;14(2):020501.
2009: WB Edwards; Akers Walter; Yunpeng Ye; Philip P Cheney; Sharon Bloch; Baogang Xu; Richard Laforest; Samuel achilefu
Multimodal imaging of integrin receptor-positive tumors by bioluminescence, fluorescence, gamma scintigraphy, and single-photon emission computed tomography using a cyclic RGD peptide labeled with a near-infrared fluorescent dye and a radionuclide.
Molecular imaging 2009;8(2):101-10.
2009: Huimin Qian; Yueqing Gu; Min Wang; Samuel achilefu
Optimization of the near-infrared fluorescence labeling for in vivo monitoring of a protein drug distribution in animal model.
Journal of fluorescence 2009;19(2):277-84.
2009: Mikhail Y Berezin; Hyeran Lee; Akers Walter; Kevin Guo; Reece J Goiffon; Adah Almutairi; Jean M J Fréchet; Samuel achilefu
Engineering NIR dyes for fluorescent lifetime contrast.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009;2009():114-7.
2009: Mikhail Y Berezin; Jeff Kao; Samuel achilefu
pH-dependent optical properties of synthetic fluorescent imidazoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(14):3560-6.
2009: Kimberly M Hsu; Jennifer R Pratt; Akers Walter; Samuel achilefu; Wayne M Yokoyama
Murine cytomegalovirus displays selective infection of cells within hours after systemic administration.
The Journal of general virology 2009;90(Pt 1):33-43.
2009: Hyeran Lee; Mikhail Y Berezin; Kevin Guo; Jeff Kao; Samuel achilefu
Near-infrared fluorescent pH-sensitive probes via unexpected barbituric acid mediated synthesis.
Organic letters 2009;11(1):29-32.
2008: Mai Xu; Yuan Yuan; Yang Xia; Samuel achilefu
Monoclonal antibody CC188 binds a carbohydrate epitope expressed on the surface of both colorectal cancer stem cells and their differentiated progeny.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(22):7461-9.
2008: Adah Almutairi; Akers Walter; Mikhail Berezin; Samuel achilefu; Jean M J Fréchet
Monitoring the biodegradation of dendritic near-infrared nanoprobes by in vivo fluorescence imaging.
Molecular pharmaceutics 2008;5(6):1103-10.
2008: Thaddeus J Wadas; Martin Eiblmaier; Alexander Zheleznyak; Christopher D Sherman; Riccardo Ferdani; Kexian Liang; Samuel achilefu; Carolyn J Anderson
Preparation and biological evaluation of 64Cu-CB-TE2A-sst2-ANT, a somatostatin antagonist for PET imaging of somatostatin receptor-positive tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(11):1819-27.
2008: Tim O Hirche; Rym Benabid; GAETAN DESLEE; Sophie C Gangloff; Samuel achilefu; Moncef Guenounou; François Lebargy; Robert E Hancock; Azzaq Belaaouaj
Neutrophil elastase mediates innate host protection against Pseudomonas aeruginosa.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4945-54.
2008: Akers Walter; Mikhail Y Berezin; Hyeran Lee; Samuel achilefu
Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements.
Journal of biomedical optics 2008;13(5):054042.
2008: Y Pu; W B Wang; B B Das; Samuel achilefu; Robert R Alfano
Time-resolved fluorescence polarization dynamics and optical imaging of Cytate: a prostate cancer receptor-targeted contrast agent.
Applied optics 2008;47(13):2281-9.
2008: Joseph Culver; Akers Walter; Samuel achilefu
Multimodality molecular imaging with combined optical and SPECT/PET modalities.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(2):169-72.
2008: Hyeran Lee; J Christian Mason; Samuel achilefu
Synthesis and spectral properties of near-infrared aminophenyl-, hydroxyphenyl-, and phenyl-substituted heptamethine cyanines.
The Journal of organic chemistry 2008;73(2):723-5.
2008: Adah Almutairi; Steven J Guillaudeu; Mikhail Berezin; Samuel achilefu; Jean M J Fréchet
Biodegradable pH-sensing dendritic nanoprobes for near-infrared fluorescence lifetime and intensity imaging.
Journal of the American Chemical Society 2008;130(2):444-5.
2008: Charles Amoatey Odonkor; Samuel achilefu
Differential activity of caspase-3 regulates susceptibility of lung and breast tumor cell lines to Paclitaxel.
The open biochemistry journal 2008;2():121-8.
2008: Zongren Zhang; Mikhail Berezin; Jeff L-F Kao; André d'Avignon; Mingfeng Bai; Samuel achilefu
Near-infrared dichromic fluorescent carbocyanine molecules.
Angewandte Chemie (International ed. in English) 2008;47(19):3584-7.
2008: Yunpeng Ye; Sharon Bloch; Baogang Xu; Samuel achilefu
Novel near-infrared fluorescent integrin-targeted DFO analogue.
Bioconjugate chemistry 2008;19(1):225-34.
2008: WB Edwards; Baogang Xu; Akers Walter; Philip P Cheney; Kexian Liang; Buck E Rogers; Carolyn J Anderson; Samuel achilefu
Agonist-antagonist dilemma in molecular imaging: evaluation of a monomolecular multimodal imaging agent for the somatostatin receptor.
Bioconjugate chemistry 2008;19(1):192-200.
2007: Mikhail Berezin; Hyeran Lee; Akers Walter; Gregory V Nikiforovich; Samuel achilefu
Ratiometric analysis of fluorescence lifetime for probing binding sites in albumin with near-infrared fluorescent molecular probes.
Photochemistry and photobiology 2007;83(6):1371-8.
2007: Mikhail Berezin; Hyeran Lee; Akers Walter; Samuel achilefu
Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems.
Biophysical journal 2007;93(8):2892-9.
2007: Akers Walter; Frederic Lesage; Dewey Holten; Samuel achilefu
In vivo resolution of multiexponential decays of multiple near-infrared molecular probes by fluorescence lifetime-gated whole-body time-resolved diffuse optical imaging.
Molecular imaging 2007;6(4):237-46.
2007: Duanwen Shen; Kexian Liang; Yunpeng Ye; Elizabeth Tetteh; Samuel achilefu
Modulation of nuclear internalization of Tat peptides by fluorescent dyes and receptor-avid peptides.
FEBS letters 2007;581(9):1793-9.
2007: Gregory V Nikiforovich; Garland R Marshall; Samuel achilefu
Molecular modeling suggests conformational scaffolds specifically targeting five subtypes of somatostatin receptors.
Chemical biology & drug design 2007;69(3):163-9.
2007: Jennifer E Sprague; Hideki Kitaura; wei zou; Yunpeng Ye; Samuel achilefu; Katherine N Weilbaecher; Steven L Teitelbaum; Carolyn J Anderson
Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(2):311-8.
2006: Hyeran Lee; J Christian Mason; Samuel achilefu
Heptamethine cyanine dyes with a robust C-C bond at the central position of the chromophore.
The Journal of organic chemistry 2006;71(20):7862-5.
2006: Sharon Bloch; Baogang Xu; Yunpeng Ye; Kexian Liang; Gregory V Nikiforovich; Samuel achilefu
Targeting Beta-3 integrin using a linear hexapeptide labeled with a near-infrared fluorescent molecular probe.
Molecular pharmaceutics 2006;3(5):539-49.
2006: Yunpeng Ye; Sharon Bloch; Baogang Xu; Samuel achilefu
Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors.
Journal of medicinal chemistry 2006;49(7):2268-75.
2006: Jennifer E Sprague; Wen Ping Li; Kexian Liang; Samuel achilefu; Carolyn J Anderson
In vitro and in vivo investigation of matrix metalloproteinase expression in metastatic tumor models.
Nuclear medicine and biology 2006;33(2):227-37.
2006: Sachin V Patwardhan; Sharon Bloch; Samuel achilefu; Joseph P Culver
Quantitative small animal fluorescence tomography using an ultrafast gated image intensifier.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():2675-8.
2005: Zongren Zhang; Samuel achilefu
Design, synthesis and evaluation of near-infrared fluorescent pH indicators in a physiologically relevant range.
Chemical communications (Cambridge, England) 2005;(47):5887-9.
2005: Zongren Zhang; Samuel achilefu
Spectral properties of pro-multimodal imaging agents derived from a NIR dye and a metal chelator.
Photochemistry and photobiology 2005;81(6):1499-504.
2005: Sharon Bloch; Frédéric Lesage; Laura McIntosh; Amir H Gandjbakhche; Kexian Liang; Samuel achilefu
Whole-body fluorescence lifetime imaging of a tumor-targeted near-infrared molecular probe in mice.
Journal of biomedical optics 2005;10(5):054003.
2005: Yihui Chen; Amy Gryshuk; Samuel achilefu; Tymish Ohulchanskyy; William Potter; Tuoxiu Zhong; Janet Morgan; Britton Chance; Paras N Prasad; Barbara W Henderson; Allan R Oseroff; Ravindra K Pandey
A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy.
Bioconjugate chemistry 2005;16(5):1264-74.
2005: Zongren Zhang; Kexian Liang; Sharon Bloch; Mikhail Berezin; Samuel achilefu
Monomolecular multimodal fluorescence-radioisotope imaging agents.
Bioconjugate chemistry 2005;16(5):1232-9.
2005: Y Pu; W B Wang; G C Tang; F Zeng; Samuel achilefu; Jack Vitenson; I Sawczuk; S Peters; J M Lombardo; Robert R Alfano
Spectral polarization imaging of human prostate cancer tissue using a near-infrared receptor-targeted contrast agent.
Technology in cancer research & treatment 2005;4(4):429-36.
2005: Samuel achilefu; Sharon Bloch; Mary A. Markiewicz; Tuoxiu Zhong; Yunpeng Ye; Richard B Dorshow; Britton Chance; Kexian Liang
Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(22):7976-81.
2005: Sachin Patwardhan; Sharon Bloch; Samuel achilefu; Joseph Culver
Time-dependent whole-body fluorescence tomography of probe bio-distributions in mice.
Optics express 2005;13(7):2564-77.
2005: Yunpeng Ye; Sharon Bloch; Jeffery Kao; Samuel achilefu
Multivalent carbocyanine molecular probes: synthesis and applications.
Bioconjugate chemistry 2005;16(1):51-61.
2004: Jennifer E Sprague; Yijie Peng; Xiankai Sun; Gary R Weisman; Edward H Wong; Samuel achilefu; Carolyn J Anderson
Preparation and biological evaluation of copper-64-labeled tyr3-octreotate using a cross-bridged macrocyclic chelator.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8674-82.
2004: Samuel achilefu
Lighting up tumors with receptor-specific optical molecular probes.
Technology in cancer research & treatment 2004;3(4):393-409.
2004: Yunpeng Ye; Sharon Bloch; Samuel achilefu
Polyvalent carbocyanine molecular beacons for molecular recognitions.
Journal of the American Chemical Society 2004;126(25):7740-1.
2004: Zongren Zhang; Samuel achilefu
Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes.
Organic letters 2004;6(12):2067-70.
2003: Yu Chen; Gang Zheng; Z H Zhang; Dana Blessington; Min Zhang; Hui Li; Q Liu; L Zhou; Xavier Intes; Samuel achilefu; Britton Chance
Metabolism-enhanced tumor localization by fluorescence imaging: in vivo animal studies.
Optics letters 2003;28(21):2070-2.
2003: Virgil A S H Dalm; P Martin van Hagen; Peter M Van Koetsveld; Samuel achilefu; Adriaan B Houtsmuller; David H J Pols; Aart Jan Van der Lely; Steven W J Lamberts; Leo J Hofland
Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells.
American journal of physiology. Endocrinology and metabolism 2003;285(2):E344-53.
2003: Samuel achilefu; Ananthacari Srinivasan; Michelle A Schmidt; Hermo N Jimenez; Joseph E Bugaj; Jack Erion
Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors.
Journal of medicinal chemistry 2003;46(15):3403-11.
2003: Yunpeng Ye; Wen Ping Li; Carolyn J Anderson; Jeffery Kao; Gregory V Nikiforovich; Samuel achilefu
Synthesis and characterization of a macrocyclic near-infrared optical scaffold.
Journal of the American Chemical Society 2003;125(26):7766-7.
2002: Jason S Lewis; Samuel achilefu; Joel R Garbow; Richard Laforest; Michael J Welch
Small animal imaging. current technology and perspectives for oncological imaging.
European journal of cancer (Oxford, England : 1990) 2002;38(16):2173-88.
2002: Samuel achilefu; Hermo N Jimenez; Richard B Dorshow; Joseph E Bugaj; Elizabeth G Webb; R Randy Wilhelm; Raghavan Rajagopalan; Jill Johler; Jack Erion
Synthesis, in vitro receptor binding, and in vivo evaluation of fluorescein and carbocyanine peptide-based optical contrast agents.
Journal of medicinal chemistry 2002;45(10):2003-15.
2001: Joseph E Bugaj; Samuel achilefu; Richard B Dorshow; Raghavan Rajagopalan
Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform.
Journal of biomedical optics 2001;6(2):122-33.
2000: Samuel achilefu; Richard B Dorshow; Joseph E Bugaj; Raghavan Rajagopalan
Novel receptor-targeted fluorescent contrast agents for in vivo tumor imaging.
Investigative radiology 2000;35(8):479-85.
2000: Samuel achilefu; R R Wilhelm; Hermo N Jimenez; Michelle A Schmidt; Ananthacari Srinivasan
A new method for the synthesis of tri-tert-butyl diethylenetriaminepentaacetic acid and its derivatives.
The Journal of organic chemistry 2000;65(5):1562-5.
2000: Raghavan Rajagopalan; P Uetrecht; Joseph E Bugaj; Samuel achilefu; Richard B Dorshow
Stabilization of the optical tracer agent indocyanine green using noncovalent interactions.
Photochemistry and photobiology 2000;71(3):347-50.
1999: C Gerardin-Charbonnier; S Auberger; L Molina; Samuel achilefu; M A Manresa; P Vinardell; M Rosa Infante; C Selve
Preparation and antibiotic activity of monobactam analogues of nocardicins.
Preparative biochemistry & biotechnology 1999;29(3):257-72.

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