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Brian Chait

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

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TOP 3
Shaun E Peterson; Foon Wu-Baer; Hong Yan; Richard Baer; Brian T Chait; Max E Gottesman; Yinyin Li; Jean Gautier
Activation of DSB processing requires phosphorylation of CtIP by ATR.
Yong-Seok Oh; Dinshaw J Patel; Ji-Seon Seo; Xiaozhu Zhang; Jung-Hyuck Ahn; Ilaria Ceglia; Brian T Chait; Pu Gao; Yong Kim; Ko-Woon Lee; Paul Greengard
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
Michela Di Virgilio; Niklas Feldhahn; Alexander D Gitlin; Mila Jankovic; André Nussenzweig; Thiago Y Oliveira; Wolfgang Resch; Davide F Robbiani; Arito Yamane; Wenzhu Zhang; Elsa Callen; Rafael Casellas; Brian T Chait; Michel C Nussenzweig
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.

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All Publications

2013: Shaun E Peterson; Foon Wu-Baer; Hong Yan; Richard Baer; Brian T Chait; Max E Gottesman; Yinyin Li; Jean Gautier
Activation of DSB processing requires phosphorylation of CtIP by ATR.
Molecular cell 2013;49(4):657-67.
2013: Yong-Seok Oh; Dinshaw J Patel; Ji-Seon Seo; Xiaozhu Zhang; Jung-Hyuck Ahn; Ilaria Ceglia; Brian T Chait; Pu Gao; Yong Kim; Ko-Woon Lee; Paul Greengard
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
Cell 2013;152(4):831-43.
2013: Michela Di Virgilio; Niklas Feldhahn; Alexander D Gitlin; Mila Jankovic; André Nussenzweig; Thiago Y Oliveira; Wolfgang Resch; Davide F Robbiani; Arito Yamane; Wenzhu Zhang; Elsa Callen; Rafael Casellas; Brian T Chait; Michel C Nussenzweig
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Science (New York, N.Y.) 2013;339(6120):711-5.
2012: Swapnil Bhatia; Brian T Chait; Lourdes Cruz; Yong J Kil; Bingwen Lu; Lemmuel Tayo; Beatrix Ueberheide; John R Yates; Marshall Bern
Constrained de novo sequencing of conotoxins.
Journal of proteome research 2012;11(8):4191-200.
2012: Anupam K Chakravarty; Brian T Chait; Roman Subbotin; Stewart Shuman
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(16):6072-7.
2012: Javier Fernandez-Martinez; Josef D Franke; Jeremy Phillips; Andrej Sali; Matthew Sekedat; David L Stokes; Javier Velazquez-Muriel; Rosemary Williams; Brian T Chait; Ruben Diaz-Avalos; Michael P Rout
Structure-function mapping of a heptameric module in the nuclear pore complex.
The Journal of cell biology 2012;196(4):419-34.
2012: Xiang Li; Yinyin Li; Kelly R Molloy; Brian T Chait; Emily A Foley; Tarun M Kapoor
Quantitative chemical proteomics approach to identify post-translational modification-mediated protein-protein interactions.
Journal of the American Chemical Society 2012;134(4):1982-5.
2012: James M Manning; Julio C Padovan; Anthony Popowicz; Brian T Chait; Lois R Manning
Intrinsic regulation of hemoglobin expression by variable subunit interface strengths.
The FEBS journal 2012;279(3):361-9.
2012: Laura T Donlin; Carol C Gregorio; Erica Y Jacobs; Steffen Just; Martina Kruger; Christopher T Pappas; Wolfgang Rottbauer; Eugene Rudensky; Alexander Tarakhovsky; Andreas Unger; Tobias Voelkel; Anke Zieseniss; Christian Andresen; Brian T Chait; Marc-Werner Dobenecker; Wolfgang A Linke
Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization.
Genes & development 2012;26(2):114-9.
2012: Miki Jishage; Sohail Malik; Bing Ren; Brian T Chait; Averell Gnatt; Xiaopeng Hu; Yasushi Ishihama; Beatrix Uberheide; Ulrich Wagner; Robert G Roeder
Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II.
Molecular cell 2012;45(1):51-63.
2012: Leonia Bozzacco; Brian T Chait; Haiteng Deng; Jörn Dengjel; Victoria Küttner; Svetlana Mojsov; Ralph M Steinman; Christine Trumpfheller; Beatrix Ueberheide; Haiqiang Yu; Henry A Zebroski; Nawei Zhang; David Fenyö
Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.
PloS one 2012;7(7):e41897.
2012: Elizabeth A Heller; Inés Ibañez-Tallon; Julio Santos-Torres; Fekrije Selimi; Wenzhu Zhang; Marta A Ślimak; Chiye Aoki; Brian T Chait; John C Earnheart; Nathaniel Heintz
The biochemical anatomy of cortical inhibitory synapses.
PloS one 2012;7(6):e39572.
2011: Carola Wilczek; Eileen Woo; Brian T Chait; Raghu Chitta; Donald F Hunt; Jeffrey Shabanowitz; David Shechter
Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs.
The Journal of biological chemistry 2011;286(49):42221-31.
2011: Johannes F Scheid; Michael S Seaman; Beatrix Ueberheide; Klara Velinzon; Bruce D Walker; Thiago Y K Oliveira; Florencia Pereyra; John Pietzsch; Pascal Poignard; Alexander Abadir; Pamela J Bjorkman; Farid Boulad; Dennis R Burton; Brian T Chait; Ron Diskin; David Fenyo; David D Ho; Arlene Hurley; Florian Klein; Hugo Mouquet; Sunnie Myung; Michel C Nussenzweig
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science (New York, N.Y.) 2011;333(6049):1633-7.
2011: Shaun E Peterson; Richard Baer; Brian T Chait; Max E Gottesman; Yinyin Li; Jean Gautier
Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
The Journal of cell biology 2011;194(5):705-20.
2011: Brian T Chait
Mass spectrometry in the postgenomic era.
Annual review of biochemistry 2011;80():239-46.
2011: Svetlana Dokudovskaya; Francois Waharte; Avner Schlessinger; Ursula Pieper; Damien Devos; Ileana M Cristea; Rosemary Williams; Jean Salamero; Brian T Chait; Andrej Sali; Mark Field; Michael P Rout; Catherine Dargemont
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.
Molecular & cellular proteomics : MCP 2011;10(6):M110.006478.
2011: Ileana M Cristea; Brian T Chait
Conjugation of magnetic beads for immunopurification of protein complexes.
Cold Spring Harbor protocols 2011;2011(5):pdb.prot5610.
2011: Ileana M Cristea; Brian T Chait
Affinity purification of protein complexes.
Cold Spring Harbor protocols 2011;2011(5):pdb.prot5611.
2011: Joanna Bloom; Ileana M Cristea; Andrea L Procko; Veronica Lubkov; Brian T Chait; Michael Snyder; Frederick R Cross
Global analysis of Cdc14 phosphatase reveals diverse roles in mitotic processes.
The Journal of biological chemistry 2011;286(7):5434-45.
2011: Anna Gazumyan; Ksenia Timachova; Grace Yuen; Edward Siden; Michela Di Virgilio; Eileen M Woo; Brian T Chait; Bernardo Reina-San-Martin; Michel C Nussenzweig; Kevin M McBride
Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Molecular and cellular biology 2011;31(3):442-9.
2011: Zhanna Berdygulova; Lars F Westblade; Laurence Florens; Eugene V Koonin; Brian T Chait; Erlan Ramanculov; Michael Washburn; Seth A Darst; Konstantin Severinov; Leonid Minakhin
Temporal regulation of gene expression of the Thermus thermophilus bacteriophage P23-45.
Journal of molecular biology 2011;405(1):125-42.
2011: Xianting Li; Qing Jun Wang; Nina Pan; Sangkyu Lee; Yingming Zhao; Brian T Chait; Zhenyu Yue
Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease.
PloS one 2011;6(3):e17153.
2010: Yinyin Li; Nichole K Stewart; Anthony J Berger; Seychelle Vos; Allyn J Schoeffler; James M Berger; Brian T Chait; Martha G Oakley
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):18832-7.
2010: Lois R Manning; Anthony Popowicz; Julio Padovan; Brian T Chait; J Eric Russell; James M Manning
Developmental expression of human hemoglobins mediated by maturation of their subunit interfaces.
Protein science : a publication of the Protein Society 2010;19(8):1595-9.
2010: Ileana M Cristea; Nathaniel J. Moorman; Scott S Terhune; Christian D Cuevas; Erin S O'Keefe; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.
Journal of virology 2010;84(15):7803-14.
2010: Ileana M Cristea; Heather Rozjabek; Kelly R Molloy; Sophiya Karki; Laura L White; Charles M Rice; Michael P Rout; Brian T Chait; Margaret R MacDonald
Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication.
Journal of virology 2010;84(13):6720-32.
2010: Anton Zilman; Stefano Di Talia; Tijana Jovanovic-Talisman; Brian T Chait; Michael P Rout; Marcelo O Magnasco
Enhancement of transport selectivity through nano-channels by non-specific competition.
PLoS computational biology 2010;6(6):e1000804.
2010: Guoan Zhang; Beatrix M Ueberheide; Sofia Waldemarson; Sunnie Myung; Kelly Molloy; Jan Eriksson; Brian T Chait; Thomas A Neubert; David Fenyö
Protein quantitation using mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 2010;673():211-22.
2010: Scott S Terhune; Nathaniel J. Moorman; Ileana M Cristea; John Paul Savaryn; Christian Cuevas-Bennett; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.
PLoS pathogens 2010;6(6):e1000965.
2010: Matthew D Sekedat; David Fenyö; Richard S Rogers; Alan J Tackett; John D Aitchison; Brian T Chait
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome.
Molecular systems biology 2010;6():353.
2010: Dragana Nesić; Marshall C Miller; Zachary T Quinkert; Markus Stein; Brian T Chait; C Erec Stebbins
Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates.
Nature structural & molecular biology 2010;17(1):130-2.
2009: Lisa Postow; Eileen M Woo; Brian T Chait; Hironori Funabiki
Identification of SMARCAL1 as a component of the DNA damage response.
The Journal of biological chemistry 2009;284(51):35951-61.
2009: Marlene Oeffinger; Daniel Zenklusen; Angelica Ferguson; Karen E Wei; Aziz El Hage; David Tollervey; Brian T Chait; Robert H Singer; Michael P Rout
Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA.
Molecular cell 2009;36(5):768-81.
2009: Jeffrey A DeGrasse; Kelly N DuBois; Damien Devos; T Nicolai Siegel; Andrej Sali; Mark Field; Michael P Rout; Brian T Chait
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor.
Molecular & cellular proteomics : MCP 2009;8(9):2119-30.
2009: Amrita Basu; Kristie L Rose; Junmei Zhang; Ronald C Beavis; Beatrix Ueberheide; Benjamin A Garcia; Brian T Chait; Y Zhao; Donald F Hunt; Eran Segal; C David Allis; Sandra B Hake
Proteome-wide prediction of acetylation substrates.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):13785-90.
2009: Brian Reed; Jack Varon; Brian T Chait; Mary Jeanne Kreek
Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin.
Endocrinology 2009;150(6):2934-9.
2009: Beatrix Ueberheide; David Fenyö; Paul F Alewood; Brian T Chait
Rapid sensitive analysis of cysteine rich peptide venom components.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):6910-5.
2009: Fekrije Selimi; Ileana M Cristea; Elizabeth Heller; Brian T Chait; Nathaniel Heintz
Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse.
PLoS biology 2009;7(4):e83.
2009: Yun Zhong; Qing Jun Wang; Xianting Li; Ying Yan; Jonathan M Backer; Brian T Chait; Nathaniel Heintz; Zhenyu Yue
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
Nature cell biology 2009;11(4):468-76.
2009: Tijana Jovanovic-Talisman; Jaclyn Tetenbaum-Novatt; Anna Sophia McKenney; Anton Zilman; Reiner Peters; Michael P Rout; Brian T Chait
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex.
Nature 2009;457(7232):1023-7.
2009: Zhenyu Yue; Gay Robbins Holstein; Brian T Chait; Qing Jun Wang
Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system.
Methods in enzymology 2009;453():159-80.
2008: Christoph Seibert; Christopher T Veldkamp; Francis C Peterson; Brian T Chait; Brian F Volkman; Thomas P Sakmar
Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases.
Biochemistry 2008;47(43):11251-62.
2008: Kevin M McBride; Anna Gazumyan; Eileen M Woo; Tanja A Schwickert; Brian T Chait; Michel C Nussenzweig
Regulation of class switch recombination and somatic mutation by AID phosphorylation.
The Journal of experimental medicine 2008;205(11):2585-94.
2008: Lisa Postow; Cristina Ghenoiu; Eileen M Woo; Andrew N Krutchinsky; Brian T Chait; Hironori Funabiki
Ku80 removal from DNA through double strand break-induced ubiquitylation.
The Journal of cell biology 2008;182(3):467-79.
2008: B Reed; Jean M Bidlack; Brian T Chait; Mary Jeanne Kreek
Extracellular biotransformation of beta-endorphin in rat striatum and cerebrospinal fluid.
Journal of neuroendocrinology 2008;20(5):606-16.
2008: Nathaniel J. Moorman; Ileana M Cristea; Scott S Terhune; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex.
Cell host & microbe 2008;3(4):253-62.
2008: Eileen M Woo; David Fenyo; Benjamin H Kwok; Hironori Funabiki; Brian T Chait
Efficient identification of phosphorylation by mass spectrometric phosphopeptide fingerprinting.
Analytical chemistry 2008;80(7):2419-25.
2008: Eduardo R Butelman; Brian Reed; Brian T Chait; Marek Mandau; Vadim Yuferov; Mary Jeanne Kreek
Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates.
Psychoneuroendocrinology 2008;33(3):292-304.
2008: Dhruti Savalia; Lars F Westblade; Manisha Goel; Laurence Florens; Priscilla Kemp; Natalja Akulenko; Olga Pavlova; Julio C Padovan; Brian T Chait; Michael Washburn; Hans-W Ackermann; Arcady Mushegian; Tarasii Gabisonia; Ian Molineux; Konstantin Severinov
Genomic and proteomic analysis of phiEco32, a novel Escherichia coli bacteriophage.
Journal of molecular biology 2008;377(3):774-89.
2008: Lars F Westblade; Leonid Minakhin; Konstantin Kuznedelov; Alan J Tackett; Emmanuel J Chang; Rachel A Mooney; Irina Vvedenskaya; Qing Jun Wang; David Fenyö; Michael P Rout; Robert Landick; Brian T Chait; Konstantin Severinov; Seth A Darst
Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions.
Journal of proteome research 2008;7(3):1244-50.
2008: Brian T Chait
Brian Chait: master of mass spectrometry. Interview by Ruth Williams.
The Journal of cell biology 2008;180(4):652-3.
2008: David Lee; Stephen J W Busby; Lars F Westblade; Brian T Chait
Affinity isolation and I-DIRT mass spectrometric analysis of the Escherichia coli O157:H7 Sakai RNA polymerase complex.
Journal of bacteriology 2008;190(4):1284-9.
2008: Jeffrey A DeGrasse; Brian T Chait; Mark Field; Michael P Rout
High-yield isolation and subcellular proteomic characterization of nuclear and subnuclear structures from trypanosomes.
Methods in molecular biology (Clifton, N.J.) 2008;463():77-92.
2007: Frank Alber; Svetlana Dokudovskaya; Liesbeth M Veenhoff; Wenzhu Zhang; Julia Kipper; Damien Devos; Adisetyantari Suprapto; Orit Karni-Schmidt; Rosemary Williams; Brian T Chait; Andrej Sali; Michael P Rout
The molecular architecture of the nuclear pore complex.
Nature 2007;450(7170):695-701.
2007: Frank Alber; Svetlana Dokudovskaya; Liesbeth M Veenhoff; Wenzhu Zhang; Julia Kipper; Damien Devos; Adisetyantari Suprapto; Orit Karni-Schmidt; Rosemary Williams; Brian T Chait; Michael P Rout; Andrej Sali
Determining the architectures of macromolecular assemblies.
Nature 2007;450(7170):683-94.
2007: Jens Brandenburg; Bernd Schimanski; Everson Nogoceke; Tu N Nguyen; Júlio C Padovan; Brian T Chait; George A M Cross; Arthur Günzl
Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex.
The EMBO journal 2007;26(23):4856-66.
2007: Marlene Oeffinger; Karen E Wei; Richard Rogers; Jeffrey A DeGrasse; Brian T Chait; John D Aitchison; Michael P Rout
Comprehensive analysis of diverse ribonucleoprotein complexes.
Nature methods 2007;4(11):951-6.
2007: Motohiko Nishida; Martine Cadene; Brian T Chait; Roderick MacKinnon
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera.
The EMBO journal 2007;26(17):4005-15.
2007: Masaaki Komatsu; Qing Jun Wang; Gay Robbins Holstein; Victor L Friedrich; Jun-ichi Iwata; Eiki Kominami; Brian T Chait; Keiji Tanaka; Zhenyu Yue
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14489-94.
2007: Srinath C Sampath; Ivan Marazzi; Kyoko L Yap; Srinath C Sampath; Andrew N Krutchinsky; Ingrid Mecklenbräuker; Agnes Viale; Eugene Rudensky; Ming-Ming Zhou; Brian T Chait; Alexander Tarakhovsky
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly.
Molecular cell 2007;27(4):596-608.
2007: Lois R Manning; J Eric Russell; Julio C Padovan; Brian T Chait; Anthony Popowicz; Robert S Manning; James M Manning
Human embryonic, fetal, and adult hemoglobins have different subunit interface strengths. Correlation with lifespan in the red cell.
Protein science : a publication of the Protein Society 2007;16(8):1641-58.
2007: Anton Zilman; Stefano Di Talia; Brian T Chait; Michael P Rout; Marcelo O Magnasco
Efficiency, selectivity, and robustness of nucleocytoplasmic transport.
PLoS computational biology 2007;3(7):e125.
2007: Joseph Stephen Glavy; Andrew N Krutchinsky; Ileana M Cristea; Ian C Berke; Thomas Boehmer; Günter Blobel; Brian T Chait
Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3811-6.
2007: SEAN TAVERNA; Beatrix Ueberheide; Yifan Liu; Alan J Tackett; Robert L Diaz; Jeffrey Shabanowitz; Brian T Chait; Donald F Hunt; C David Allis
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2086-91.
2007: David Fenyo; Qingjun Wang; Jeffrey A DeGrasse; Julio C Padovan; Martine Cadene; Brian T Chait
MALDI sample preparation: the ultra thin layer method.
Journal of visualized experiments : JoVE 2007;(3):192.
2007: Emmanuel J Chang; Rashida Begum; Brian T Chait; Terry Gaasterland
Prediction of cyclin-dependent kinase phosphorylation substrates.
PloS one 2007;2(7):e656.
2007: Alexander E Kelly; Srinath C Sampath; Tapan A Maniar; Eileen M Woo; Brian T Chait; Hironori Funabiki
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.
Developmental cell 2007;12(1):31-43.
2006: SEAN TAVERNA; Sergey Ilin; Richard S Rogers; Jason Tanny; Heather Lavender; Haitao Li; Lindsey Baker; John Boyle; Lauren P Blair; Brian T Chait; Dinshaw J Patel; John D Aitchison; Alan J Tackett; C David Allis
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.
Molecular cell 2006;24(5):785-96.
2006: Benjamin L Timney; Jaclyn Tetenbaum-Novatt; Diana S Agate; Rosemary Williams; Wenzhu Zhang; Brian T Chait; Michael P Rout
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo.
The Journal of cell biology 2006;175(4):579-93.
2006: Brian T Chait
Chemistry. Mass spectrometry: bottom-up or top-down?
Science (New York, N.Y.) 2006;314(5796):65-6.
2006: Ileana M Cristea; John-William N Carroll; Michael P Rout; Charles M Rice; Brian T Chait; Margaret R MacDonald
Tracking and elucidating alphavirus-host protein interactions.
The Journal of biological chemistry 2006;281(40):30269-78.
2006: Qing Jun Wang; Yaomei Ding; D Stave Kohtz; Stave Kohtz; Noboru Mizushima; Ileana M Cristea; Michael P Rout; Brian T Chait; Yun Zhong; Nathaniel Heintz; Zhenyu Yue
Induction of autophagy in axonal dystrophy and degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(31):8057-68.
2006: Joanna Wysocka; Tomek Swigut; Hua Xiao; Thomas A Milne; So Yeon Kwon; Joe Landry; Monika Kauer; Alan J Tackett; Brian T Chait; Paul Badenhorst; Carl Wu; C David Allis
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.
Nature 2006;442(7098):86-90.
2006: Kevin M McBride; Anna Gazumyan; Eileen M Woo; Vasco M Barreto; Davide F Robbiani; Brian T Chait; Michel C Nussenzweig
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8798-803.
2006: Mohamed Guermah; Vikas Palhan; Alan J Tackett; Brian T Chait; Robert G Roeder
Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates.
Cell 2006;125(2):275-86.
2006: Svetlana Dokudovskaya; Rosemary Williams; Damien Devos; Andrej Sali; Brian T Chait; Michael P Rout
Protease accessibility laddering: a proteomic tool for probing protein structure.
Structure (London, England : 1993) 2006;14(4):653-60.
2006: Wen-Yen Kao; Jun Qin; Kenzo Fushitani; Sandra S Smith; Thomas A Gorr; Claire K Riggs; James E Knapp; Brian T Chait; Austen F Riggs
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Proteins 2006;63(1):174-87.
2006: Damien Devos; Svetlana Dokudovskaya; Rosemary Williams; Frank Alber; Narayanan Eswar; Brian T Chait; Michael P Rout; Andrej Sali
Simple fold composition and modular architecture of the nuclear pore complex.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2172-7.
2005: David J Dilworth; Alan J Tackett; Richard S Rogers; Eugene C Yi; Rowan H Christmas; Jennifer J Smith; Andrew F Siegel; Brian T Chait; Richard W Wozniak; John D Aitchison
The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control.
The Journal of cell biology 2005;171(6):955-65.
2005: Mi Jin; Helen Bateup; Júlio C Padovan; Paul Greengard; Angus Nairn; Brian T Chait
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
Analytical chemistry 2005;77(24):7845-51.
2005: Ileana M Cristea; Rosemary Williams; Brian T Chait; Michael P Rout
Fluorescent proteins as proteomic probes.
Molecular & cellular proteomics : MCP 2005;4(12):1933-41.
2005: Caterina Strambio-De-Castillia; Jaclyn Tetenbaum-Novatt; Brian S Imai; Brian T Chait; Michael P Rout
A method for the rapid and efficient elution of native affinity-purified protein A tagged complexes.
Journal of proteome research 2005;4(6):2250-6.
2005: Peter Höök; Atsushi Mikami; Beth Shafer; Brian T Chait; Steven S Rosenfeld; Richard B Vallee
Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains.
The Journal of biological chemistry 2005;280(38):33045-54.
2005: Alan J Tackett; Jeffrey A DeGrasse; Matthew Sekedat; Marlene Oeffinger; Michael P Rout; Brian T Chait
I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions.
Journal of proteome research 2005;4(5):1752-6.
2005: Mario Niepel; Caterina Strambio-De-Castillia; Joseph Fasolo; Brian T Chait; Michael P Rout
The nuclear pore complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly.
The Journal of cell biology 2005;170(2):225-35.
2005: Xiaoting Zhang; Andrew N Krutchinsky; Aya Fukuda; Wei Chen; Soichiro Yamamura; Brian T Chait; Robert G Roeder
MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.
Molecular cell 2005;19(1):89-100.
2005: Yali Dou; Thomas A Milne; Alan J Tackett; Edwin R Smith; Aya Fukuda; Joanna Wysocka; C David Allis; Brian T Chait; Jay L Hess; Robert G Roeder
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
Cell 2005;121(6):873-85.
2005: Vikas Palhan; Shiming Chen; Guang-Hua Peng; Agneta Tjernberg; Armin Gamper; Yuxin Fan; Brian T Chait; Albert R La Spada; Robert G Roeder
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8472-7.
2005: Makoto Ashiuchi; Takeshi Yagami; Ronald J Willey; Julio C Padovan; Brian T Chait; Anthony Popowicz; Lois R Manning; James M Manning
N-terminal acetylation and protonation of individual hemoglobin subunits: position-dependent effects on tetramer strength and cooperativity.
Protein science : a publication of the Protein Society 2005;14(6):1458-71.
2005: Masayuki Matsushita; J Ashot Kozak; Yoshio Shimizu; Derek T McLachlin; Hiroto Yamaguchi; Fan-Yan Wei; Kazuhito Tomizawa; Hideki Matsui; Brian T Chait; Michael D Cahalan; Angus Nairn
Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.
The Journal of biological chemistry 2005;280(21):20793-803.
2005: Alan J Tackett; David J Dilworth; Megan J Davey; Michael O'Donnell; John D Aitchison; Michael P Rout; Brian T Chait
Proteomic and genomic characterization of chromatin complexes at a boundary.
The Journal of cell biology 2005;169(1):35-47.
2005: László Csanády; Donna Seto-Young; Kim W Chan; Cristina Cenciarelli; Benjamin B Angel; Jun Qin; Derek T McLachlin; Andrew N Krutchinsky; Brian T Chait; Angus Nairn; David C Gadsby
Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.
The Journal of general physiology 2005;125(2):171-86.
2004: Damien Devos; Svetlana Dokudovskaya; Frank Alber; Rosemary Williams; Brian T Chait; Andrej Sali; Michael P Rout
Components of coated vesicles and nuclear pore complexes share a common molecular architecture.
PLoS biology 2004;2(12):e380.
2004: Jeffrey Zheng-Sheng Ye; Jill R Donigian; Megan van Overbeek; Diego Loayza; Yan Luo; Andrew N Krutchinsky; Brian T Chait; Titia de Lange
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.
The Journal of biological chemistry 2004;279(45):47264-71.
2004: Vasant Muralidharan; Jaehyun Cho; Michelle Trester-Zedlitz; Lukasz Kowalik; Brian T Chait; Daniel P Raleigh; Tom W Muir
Domain-specific incorporation of noninvasive optical probes into recombinant proteins.
Journal of the American Chemical Society 2004;126(43):14004-12.
2004: Deena M Leslie; Wenzhu Zhang; Benjamin L Timney; Brian T Chait; Michael P Rout; Richard W Wozniak; John D Aitchison
Characterization of karyopherin cargoes reveals unique mechanisms of Kap121p-mediated nuclear import.
Molecular and cellular biology 2004;24(19):8487-503.
2004: Maria Magdalena Coman; Mi Jin; Razvan Ceapa; Jeff Finkelstein; Michael O'Donnell; Brian T Chait; Manju M Hingorani
Dual functions, clamp opening and primer-template recognition, define a key clamp loader subunit.
Journal of molecular biology 2004;342(5):1457-69.
2004: Jinsong Zhang; Markus Kalkum; Soichiro Yamamura; Brian T Chait; Robert G Roeder
E protein silencing by the leukemogenic AML1-ETO fusion protein.
Science (New York, N.Y.) 2004;305(5688):1286-9.
2004: Emmanuel J Chang; Vincent Archambault; Derek T McLachlin; Andrew N Krutchinsky; Brian T Chait
Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry.
Analytical chemistry 2004;76(15):4472-83.
2004: Jeffrey Zheng-Sheng Ye; Dirk Hockemeyer; Andrew N Krutchinsky; Diego Loayza; Sarah M Hooper; Brian T Chait; Titia de Lange
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Genes & development 2004;18(14):1649-54.
2004: Vincent Archambault; Emmanuel J Chang; Benjamin J Drapkin; Frederick R Cross; Brian T Chait; Michael P Rout
Targeted proteomic study of the cyclin-Cdk module.
Molecular cell 2004;14(6):699-711.
2003: Derek T McLachlin; Brian T Chait
Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides.
Analytical chemistry 2003;75(24):6826-36.
2003: Michael P Rout; John D Aitchison; Marcelo O Magnasco; Brian T Chait
Virtual gating and nuclear transport: the hole picture.
Trends in cell biology 2003;13(12):622-8.
2003: Vincent Archambault; Caihong X Li; Alan J Tackett; Ralph Wäsch; Brian T Chait; Michael P Rout; Frederick R Cross
Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exit.
Molecular biology of the cell 2003;14(11):4592-604.
2003: Kelly-Anne Wilson; Markus Kalkum; Jennifer Ottesen; Julia Yuzenkova; Brian T Chait; Robert Landick; Tom Muir; Konstantin Severinov; Seth A Darst
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail.
Journal of the American Chemical Society 2003;125(41):12475-83.
2003: John Keith Moffat; Brian T Chait
Biophysical methods: doing more with less.
Current opinion in structural biology 2003;13(5):535-7.
2003: Wenzhu Zhang; Andrew N Krutchinsky; Brian T Chait
"De novo" peptide sequencing by MALDI-quadrupole-ion trap mass spectrometry: a preliminary study.
Journal of the American Society for Mass Spectrometry 2003;14(9):1012-21.
2003: Ephraim Sehayek; Rong Wang; Jennie G Ono; Vadim S Zinchuk; Elizabeth M Duncan; Sarah Shefer; Dennis E Vance; Meenakshisundaram Ananthanarayanan; Brian T Chait; Jan L Breslow
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Journal of lipid research 2003;44(9):1605-13.
2003: Brian Reed; Yong Zhang; Brian T Chait; Mary Jeanne Kreek
Dynorphin A(1-17) biotransformation in striatum of freely moving rats using microdialysis and matrix-assisted laser desorption/ionization mass spectrometry.
Journal of neurochemistry 2003;86(4):815-23.
2003: Youxing Jiang; Alice Lee; Jiayun Chen; Vanessa Ruta; Martine Cadene; Brian T Chait; Roderick MacKinnon
X-ray structure of a voltage-dependent K+ channel.
Nature 2003;423(6935):33-41.
2003: Michelle Trester-Zedlitz; Katsuhiko Kamada; Stephen K Burley; David Fenyö; Brian T Chait; Tom W Muir
A modular cross-linking approach for exploring protein interactions.
Journal of the American Chemical Society 2003;125(9):2416-25.
2003: Markus Kalkum; Gholson J Lyon; Brian T Chait
Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2795-800.
2003: Shengkan Jin; Markus Kalkum; Michael Overholtzer; Archontoula Stoffel; Brian T Chait; Arnold J Levine
CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals.
Genes & development 2003;17(3):359-67.
2003: I-Hsin Su; Ashwin Basavaraj; Andrew N Krutchinsky; Oliver Hobert; Axel Ullrich; Brian T Chait; Alexander Tarakhovsky
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.
Nature immunology 2003;4(2):124-31.
2002: Luis Lopez-Molina; Sébastien Mongrand; Derek T McLachlin; Brian T Chait; Nam-Hai Chua
ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination.
The Plant journal : for cell and molecular biology 2002;32(3):317-28.
2002: Janet M Cronshaw; Andrew N Krutchinsky; Wenzhu Zhang; Brian T Chait; Michael J Matunis
Proteomic analysis of the mammalian nuclear pore complex.
The Journal of cell biology 2002;158(5):915-27.
2002: Christoph Seibert; Martine Cadene; Anthony Sanfiz; Brian T Chait; Thomas P Sakmar
Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11031-6.
2002: Youxing Jiang; Alice Lee; Jiayun Chen; Martine Cadene; Brian T Chait; Roderick MacKinnon
The open pore conformation of potassium channels.
Nature 2002;417(6888):523-6.
2002: Youxing Jiang; Alice Lee; Jiayun Chen; Martine Cadene; Brian T Chait; Roderick MacKinnon
Crystal structure and mechanism of a calcium-gated potassium channel.
Nature 2002;417(6888):515-22.
2002: Jayasree S Nair; Christopher J DaFonseca; Agneta Tjernberg; Wei Sun; James E Darnell; Brian T Chait; J. Jue Zhang
Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):5971-6.
2002: Christopher A Bradley; Júlio César Padovan; Timothy L Thompson; Clint A Benoit; Brian T Chait; Robert E Rhoads
Mass spectrometric analysis of the N terminus of translational initiation factor eIF4G-1 reveals novel isoforms.
The Journal of biological chemistry 2002;277(15):12559-71.
2002: Jinsong Zhang; Markus Kalkum; Brian T Chait; Robert G Roeder
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.
Molecular cell 2002;9(3):611-23.
2002: Hiroyuki Kato; Agneta Tjernberg; Wenzhu Zhang; Andrew N Krutchinsky; Woojin An; Tamotsu Takeuchi; Yuji Ohtsuki; Sumio Sugano; Diederik R de Bruijn; Brian T Chait; Robert G Roeder
SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.
The Journal of biological chemistry 2002;277(7):5498-505.
2002: Andrew N Krutchinsky; Brian T Chait
On the nature of the chemical noise in MALDI mass spectra.
Journal of the American Society for Mass Spectrometry 2002;13(2):129-34.
2002: Raimund Dutzler; Ernest B Campbell; Martine Cadene; Brian T Chait; Roderick MacKinnon
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature 2002;415(6869):287-94.
2002: Takeshi Yagami; Barry T Ballard; Julio C Padovan; Brian T Chait; Anthony Popowicz; James M Manning
N-terminal contributions of the gamma-subunit of fetal hemoglobin to its tetramer strength: remote effects at subunit contacts.
Protein science : a publication of the Protein Society 2002;11(1):27-35.
2001: Andrew N Krutchinsky; Markus Kalkum; Brian T Chait
Automatic identification of proteins with a MALDI-quadrupole ion trap mass spectrometer.
Analytical chemistry 2001;73(21):5066-77.
2001: C Yang; J Wang; A N Krutchinsky; Brian T Chait; Joel D Morrisett; Charles V Smith
Selective oxidation in vitro by myeloperoxidase of the N-terminal amine in apolipoprotein B-100.
Journal of lipid research 2001;42(11):1891-6.
2001: Derek T McLachlin; Brian T Chait
Analysis of phosphorylated proteins and peptides by mass spectrometry.
Current opinion in chemical biology 2001;5(5):591-602.
2001: E Martinez; Vikas Palhan; Agneta Tjernberg; E S Lymar; Armin Gamper; TK Kundu; Brian T Chait; Robert G Roeder
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Molecular and cellular biology 2001;21(20):6782-95.
2001: David J Dilworth; Adisetyantari Suprapto; J C Padovan; Brian T Chait; Richard W Wozniak; Michael P Rout; John D Aitchison
Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex.
The Journal of cell biology 2001;153(7):1465-78.
2001: Y Oda; T Nagasu; Brian T Chait
Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome.
Nature biotechnology 2001;19(4):379-82.
2001: Youxing Jiang; A Pico; Martine Cadene; Brian T Chait; Roderick MacKinnon
Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.
Neuron 2001;29(3):593-601.
2001: NA Linderoth; Martha N Simon; N A Rodionova; Martine Cadene; W R Laws; Brian T Chait; SS Sastry
Biophysical analysis of the endoplasmic reticulum-resident chaperone/heat shock protein gp96/GRP94 and its complex with peptide antigen.
Biochemistry 2001;40(5):1483-95.
2001: Steven Cohen; Brian T Chait
Mass spectrometry as a tool for protein crystallography.
Annual review of biophysics and biomolecular structure 2001;30():67-85.
2000: Martine Cadene; Brian T Chait
A robust, detergent-friendly method for mass spectrometric analysis of integral membrane proteins.
Analytical chemistry 2000;72(22):5655-8.
2000: K Inagaki; J Inagaki; A Dumoulin; Julio C Padovan; Brian T Chait; Anthony Popowicz; Lois R Manning; James M Manning
Expression and properties of recombinant HbA2 (alpha2delta2) and hybrids containing delta-beta sequences.
Journal of protein chemistry 2000;19(8):649-62.
2000: bassam rushdi ali; A Tjernberg; Brian T Chait; Mark Field
A microsomal GTPase is required for glycopeptide export from the mammalian endoplasmic reticulum.
The Journal of biological chemistry 2000;275(43):33222-30.
2000: S Sechi; Brian T Chait
A method to define the carboxyl terminal of proteins.
Analytical chemistry 2000;72(14):3374-8.
2000: W Zhang; Brian T Chait
ProFound: an expert system for protein identification using mass spectrometric peptide mapping information.
Analytical chemistry 2000;72(11):2482-9.
2000: Andrew N Krutchinsky; Wenzhu Zhang; Brian T Chait
Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification.
Journal of the American Society for Mass Spectrometry 2000;11(6):493-504.
2000: W Chen; A Dumoulin; Xianfeng Li; Julio C Padovan; Brian T Chait; R Buonopane; Orah Platt; Lois R Manning; James M Manning
Transposing sequences between fetal and adult hemoglobins indicates which subunits and regulatory molecule interfaces are functionally related.
Biochemistry 2000;39(13):3774-81.
2000: J Eriksson; Brian T Chait; David Fenyö
A statistical basis for testing the significance of mass spectrometric protein identification results.
Analytical chemistry 2000;72(5):999-1005.
2000: Michael P Rout; John D Aitchison; Adisetyantari Suprapto; K Hjertaas; Y Zhao; Brian T Chait
The yeast nuclear pore complex: composition, architecture, and transport mechanism.
The Journal of cell biology 2000;148(4):635-51.
2000: Steven Cohen; J C Padovan; Brian T Chait
Mass spectrometric analysis of mercury incorporation into proteins for X-ray diffraction phase determination.
Analytical chemistry 2000;72(3):574-9.
2000: SN Uljon; L Mazzarelli; Brian T Chait; Runsheng Wang
Analysis of proteins and peptides directly from biological fluids by immunoprecipitation/mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 2000;146():439-52.
1999: M Teichmann; Z Wang; E Martinez; Agneta Tjernberg; D Zhang; Frank Vollmer; Brian T Chait; Robert G Roeder
Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13720-5.
1999: Rong Wang; Brian T Chait; I Wolf; Ronald A Kohanski; Christopher Cardozo
Lysozyme degradation by the bovine multicatalytic proteinase complex (proteasome): evidence for a nonprocessive mode of degradation.
Biochemistry 1999;38(44):14573-81.
1999: T Nagata; Vineet Gupta; D Sorce; W Y Kim; Andrej Sali; Brian T Chait; Shigesada Katsuya; Y Ito; Milton H Werner
Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain.
Nature structural biology 1999;6(7):615-9.
1999: Y Oda; K Huang; F R Cross; David Cowburn; Brian T Chait
Accurate quantitation of protein expression and site-specific phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6591-6.
1999: E Maréchal; K Hiratsuka; J Delgado; Angus Nairn; J Qin; Brian T Chait; Nam-Hai Chua
Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation.
Plant molecular biology 1999;40(3):373-86.
1999: James M Manning; A Dumoulin; Lois R Manning; W Chen; Julio C Padovan; Brian T Chait; Anthony Popowicz
Remote contributions to subunit interactions: lessons from adult and fetal hemoglobins.
Trends in biochemical sciences 1999;24(6):211-2.
1999: Xianfeng Li; Juha P Himanen; J J Martin de Llano; Julio C Padovan; Brian T Chait; James M Manning
Mutational analysis of sickle haemoglobin (Hb) gelation.
Biotechnology and applied biochemistry 1999;29 ( Pt 2)():165-84.
1998: A Dumoulin; Julio C Padovan; Lois R Manning; Anthony Popowicz; RM Winslow; Brian T Chait; James M Manning
The N-terminal sequence affects distant helix interactions in hemoglobin. Implications for mutant proteins from studies on recombinant hemoglobin felix.
The Journal of biological chemistry 1998;273(52):35032-8.
1998: S Sechi; Brian T Chait
Modification of cysteine residues by alkylation. A tool in peptide mapping and protein identification.
Analytical chemistry 1998;70(24):5150-8.
1998: J. Jue Zhang; Y Zhao; Brian T Chait; W W Lathem; M Ritzi; Rolf Knippers; James E Darnell
Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.
The EMBO journal 1998;17(23):6963-71.
1998: João H Morais-Cabral; A Lee; Steven Cohen; Brian T Chait; M Li; Roderick MacKinnon
Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain.
Cell 1998;95(5):649-55.
1998: Craig L Peterson; Y Zhao; Brian T Chait
Subunits of the yeast SWI/SNF complex are members of the actin-related protein (ARP) family.
The Journal of biological chemistry 1998;273(37):23641-4.
1998: Wenzhu Zhang; S Niu; Brian T Chait
Exploring infrared wavelength matrix-assisted laser desorption/ionization of proteins with delayed-extraction time-of-flight mass spectrometry.
Journal of the American Society for Mass Spectrometry 1998;9(9):879-84.
1998: David Fenyö; J Qin; Brian T Chait
Protein identification using mass spectrometric information.
Electrophoresis 1998;19(6):998-1005.
1998: Katherine A Hajjar; L Mauri; Andrew T Jacovina; F Zhong; U A Mirza; J C Padovan; Brian T Chait
Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine.
The Journal of biological chemistry 1998;273(16):9987-93.
1998: Declan Doyle; João H Morais-Cabral; R A Pfuetzner; Anling Kuo; Jacqueline M Gulbis; Steven Cohen; Brian T Chait; Roderick MacKinnon
The structure of the potassium channel: molecular basis of K+ conduction and selectivity.
Science (New York, N.Y.) 1998;280(5360):69-77.
1998: Roderick MacKinnon; Steven Cohen; Anling Kuo; A Lee; Brian T Chait
Structural conservation in prokaryotic and eukaryotic potassium channels.
Science (New York, N.Y.) 1998;280(5360):106-9.
1998: Huaxi Xu; Gunnar K Gouras; Jeffrey P Greenfield; B Vincent; J Naslund; L Mazzarelli; G Fried; J N Jovanovic; M Seeger; Norman Richard Relkin; F Liao; F Checler; Joseph Buxbaum; Brian T Chait; Gopal Thinakaran; Sangram S Sisodia; Runsheng Wang; Paul Greengard; Sam Gandy
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Nature medicine 1998;4(4):447-51.
1998: PW van Ophem; S D Erickson; A Martinez del Pozo; Ivan Haller; Brian T Chait; T Yoshimura; K Soda; Dagmar Ringe; G Petsko; James M Manning
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
Biochemistry 1998;37(9):2879-88.
1998: S Niu; Wenzhu Zhang; Brian T Chait
Direct comparison of infrared and ultraviolet wavelength matrix-assisted laser desorption/ionization mass spectrometry of proteins.
Journal of the American Society for Mass Spectrometry 1998;9(1):1-7.
1997: Xianfeng Li; U A Mirza; Brian T Chait; James M Manning
Systematic enhancement of polymerization of recombinant sickle hemoglobin mutants: implications for transgenic mouse model for sickle cell anemia.
Blood 1997;90(11):4620-7.
1997: J Qin; Brian T Chait
Identification and characterization of posttranslational modifications of proteins by MALDI ion trap mass spectrometry.
Analytical chemistry 1997;69(19):4002-9.
1997: J Qin; David Fenyö; Y Zhao; WW Hall; D M Chao; C J Wilson; R A Young; Brian T Chait
A strategy for rapid, high-confidence protein identification.
Analytical chemistry 1997;69(19):3995-4001.
1997: J Yu; Eduardo R Butelman; James H Woods; Brian T Chait; Mary Jeanne Kreek
Dynorphin A (1-8) analog, E-2078, crosses the blood-brain barrier in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1997;282(2):633-8.
1997: Y Wang; Konstantin Severinov; N Loizos; David Fenyö; Ewa Heyduk; Tomasz Heyduk; Brian T Chait; Seth A Darst
Determinants for Escherichia coli RNA polymerase assembly within the beta subunit.
Journal of molecular biology 1997;270(5):648-62.
1997: Steven Cohen; Brian T Chait
Mass spectrometry of whole proteins eluted from sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels.
Analytical biochemistry 1997;247(2):257-67.
1997: Phoebe L Stewart; CY Chiu; Shuang Huang; T Muir; Y Zhao; Brian T Chait; P Mathias; Glen R Nemerow
Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization.
The EMBO journal 1997;16(6):1189-98.
1997: Yaofeng Zhao; S B Kent; Brian T Chait
Rapid, sensitive structure analysis of oligosaccharides.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1629-33.
1997: J Yu; Eduardo R Butelman; James H Woods; Brian T Chait; Mary Jeanne Kreek
Dynorphin A (1-8) analog, E-2078, is stable in human and rhesus monkey blood.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1147-51.
1997: Harry M Lander; DP Hajjar; Barbara L Hempstead; U A Mirza; Brian T Chait; Sharon L Campbell; Lawrence A Quilliam
A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction.
The Journal of biological chemistry 1997;272(7):4323-6.
1997: Q Xie; R A Donahue; K Schneider; U A Mirza; Ivan Haller; Brian T Chait; Austen F Riggs
Structure of chain d of the gigantic hemoglobin of the earthworm.
Biochimica et biophysica acta 1997;1337(2):241-7.
1997: Runsheng Wang; Brian T Chait
N-terminal protein ladder sequencing.
Methods in molecular biology (Clifton, N.J.) 1997;64():175-82.
1996: J G da Silva; Olga L T Machado; C Izumi; J C Padovan; Brian T Chait; U A Mirza; L J Greene
Amino acid sequence of a new 2S albumin from Ricinus communis which is part of a 29-kDa precursor protein.
Archives of biochemistry and biophysics 1996;336(1):10-8.
1996: Elena Severinova; Konstantin Severinov; David Fenyö; Michael T Marr; E N Brody; J W Roberts; Brian T Chait; Seth A Darst
Domain organization of the Escherichia coli RNA polymerase sigma 70 subunit.
Journal of molecular biology 1996;263(5):637-47.
1996: Brian T Chait
Trawling for proteins in the post-genome era.
Nature biotechnology 1996;14(11):1544.
1996: J Yu; Eduardo R Butelman; James H Woods; Brian T Chait; Mary Jeanne Kreek
In vitro biotransformation of dynorphin A (1-17) is similar in human and rhesus monkey blood as studied by matrix-assisted laser desorption/ionization mass spectrometry.
The Journal of pharmacology and experimental therapeutics 1996;279(2):507-14.
1996: Uwe Vinkemeier; Steven Cohen; Ismail Moarefi; Brian T Chait; John Kuriyan; James E Darnell
DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites.
The EMBO journal 1996;15(20):5616-26.
1996: Juha P Himanen; U A Mirza; Brian T Chait; R M Bookchin; James M Manning
A recombinant sickle hemoglobin triple mutant with independent inhibitory effects on polymerization.
The Journal of biological chemistry 1996;271(41):25152-6.
1996: Steven Cohen; JL Halaas; Jeffrey M Friedman; Brian T Chait; L Bennett; D Chang; R Hecht; F Collins
Human leptin characterization.
Nature 1996;382(6592):589.
1996: J Qin; Brian T Chait
Matrix-assisted laser desorption ion trap mass spectrometry: efficient isolation and effective fragmentation of peptide ions.
Analytical chemistry 1996;68(13):2108-12.
1996: J Qin; Brian T Chait
Matrix-assisted laser desorption ion trap mass spectrometry: efficient trapping and ejection of ions.
Analytical chemistry 1996;68(13):2102-7.
1996: C H Lee; K Saksela; U A Mirza; Brian T Chait; John Kuriyan
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell 1996;85(6):931-42.
1996: Joyce W Lustbader; Steven Birken; Susan Pollak; A Pound; Brian T Chait; U A Mirza; S Ramnarain; Robert E Canfield; J M Brown
Expression of human chorionic gonadotropin uniformly labeled with NMR isotopes in Chinese hamster ovary cells: an advance toward rapid determination of glycoprotein structures.
Journal of biomolecular NMR 1996;7(4):295-304.
1996: Harry M Lander; A J Milbank; J M Tauras; D P Hajjar; Barbara L Hempstead; G D Schwartz; R T Kraemer; U A Mirza; Brian T Chait; S C Burk; Lawrence A Quilliam
Redox regulation of cell signalling.
Nature 1996;381(6581):380-1.
1996: J Qin; J Ruud; Brian T Chait
A practical ion trap mass spectrometer for the analysis of peptides by matrix-assisted laser desorption/ionization.
Analytical chemistry 1996;68(10):1784-91.
1996: Y Zhao; Tom W Muir; S B Kent; E Tischer; J M Scardina; Brian T Chait
Mapping protein-protein interactions by affinity-directed mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4020-4.
1996: X Xie; T Kokubo; Steven Cohen; U A Mirza; A Hoffmann; Brian T Chait; Robert G Roeder; Y Nakatani; Stephen K Burley
Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature 1996;380(6572):316-22.
1996: A A Stewart; J D Haley; G Y Qu; K Stam; D Fenyö; Brian T Chait; D R Marshak; A Y Ng; G Marley; K K Iwata
Umbilical cord transforming growth factor-beta 3: isolation, comparison with recombinant TGF-beta 3 and cellular localization.
Growth factors (Chur, Switzerland) 1996;13(1-2):87-98.
1996: Y Zhao; Brian T Chait
Probing antibody-antigen interactions by mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 1996;66():129-36.
1996: Rong Wang; Brian T Chait
Posttranslational modifications analyzed by automated protein ladder sequencing.
Methods in molecular biology (Clifton, N.J.) 1996;61():161-70.
1996: J Z Chou; Brian T Chait; Rong Wang; Mary Jeanne Kreek
Differential biotransformation of dynorphin A (1-17) and dynorphin A (1-13) peptides in human blood, ex vivo.
Peptides 1996;17(6):983-90.
1996: J Yu; Brian T Chait; L Toll; Mary Jeanne Kreek
Nociceptin in vitro biotransformation in human blood.
Peptides 1996;17(5):873-6.
1996: Ronald C Beavis; Brian T Chait
Matrix-assisted laser desorption ionization mass-spectrometry of proteins.
Methods in enzymology 1996;270():519-51.
1996: Steven Cohen; Brian T Chait
Influence of matrix solution conditions on the MALDI-MS analysis of peptides and proteins.
Analytical chemistry 1996;68(1):31-7.
1995: JL Halaas; K S Gajiwala; M Maffei; Steven Cohen; Brian T Chait; daniel rabinowitz; R L Lallone; S K Burley; Jeffrey M Friedman
Weight-reducing effects of the plasma protein encoded by the obese gene.
Science (New York, N.Y.) 1995;269(5223):543-6.
1995: U A Mirza; Brian T Chait; Harry M Lander
Monitoring reactions of nitric oxide with peptides and proteins by electrospray ionization-mass spectrometry.
The Journal of biological chemistry 1995;270(29):17185-8.
1995: Juha P Himanen; K Schneider; Brian T Chait; James M Manning
Participation and strength of interaction of lysine 95(beta) in the polymerization of hemoglobin S as determined by its site-directed substitution by isoleucine.
The Journal of biological chemistry 1995;270(23):13885-91.
1995: Steven Cohen; A R Ferré-D'Amaré; Stephen K Burley; Brian T Chait
Probing the solution structure of the DNA-binding protein Max by a combination of proteolysis and mass spectrometry.
Protein science : a publication of the Protein Society 1995;4(6):1088-99.
1995: K Schneider; Brian T Chait
Increased stability of nucleic acids containing 7-deaza-guanosine and 7-deaza-adenosine may enable rapid DNA sequencing by matrix-assisted laser desorption mass spectrometry.
Nucleic acids research 1995;23(9):1570-5.
1995: Jacqueline Chauvet; G Michel; Y Ouedraogo; J Chou; Brian T Chait; Roger Acher
A new neurohypophysial peptide, seritocin ([Ser5,Ile8]-oxytocin), identified in a dryness-resistant African toad, Bufo regularis.
International journal of peptide and protein research 1995;45(5):482-7.
1995: Archil Shartava; C A Monteiro; F Aladar Bencsath; K Schneider; Brian T Chait; R Gussio; L A Casoria-Scott; Arvind K Shah; C A Heuerman; Steven R Goodman
A posttranslational modification of beta-actin contributes to the slow dissociation of the spectrin-protein 4.1-actin complex of irreversibly sickled cells.
The Journal of cell biology 1995;128(5):805-18.
1995: K Stam; A A Stewart; G Y Qu; K K Iwata; D Fenyö; Brian T Chait; D R Marshak; J D Haley
Physical and biological characterization of a growth-inhibitory activity purified from the neuroepithelioma cell line A673.
The Biochemical journal 1995;305 ( Pt 1)():87-92.
1995: S K Chowdhury; K J Vavra; P G Brake; T Banks; J Falvo; R Wahl; J Eshraghi; G Gonyea; Brian T Chait; C H Vestal
Examination of recombinant truncated mature human fibroblast collagenase by mass spectrometry: identification of differences with the published sequence and determination of stable isotope incorporation.
Rapid communications in mass spectrometry : RCM 1995;9(7):563-9.
1994: H Ge; Y Zhao; Brian T Chait; Robert G Roeder
Phosphorylation negatively regulates the function of coactivator PC4.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12691-5.
1994: H Tang; Konstantin Severinov; A Goldfarb; D Fenyo; Brian T Chait; Richard H. Ebright
Location, structure, and function of the target of a transcriptional activator protein.
Genes & development 1994;8(24):3058-67.
1994: U A Mirza; Brian T Chait
Effects of anions on the positive ion electrospray ionization mass spectra of peptides and proteins.
Analytical chemistry 1994;66(18):2898-904.
1994: Konstantin Severinov; David Fenyö; Elena Severinova; Arkady Mustaev; Brian T Chait; Alex Goldfarb; Seth A Darst
The sigma subunit conserved region 3 is part of "5'-face" of active center of Escherichia coli RNA polymerase.
The Journal of biological chemistry 1994;269(33):20826-8.
1994: T S Krishna; David Fenyö; X P Kong; S Gary; Brian T Chait; P Burgers; John Kuriyan
Crystallization of proliferating cell nuclear antigen (PCNA) from Saccharomyces cerevisiae.
Journal of molecular biology 1994;241(2):265-8.
1994: Y Yang; W V Sweeney; K Schneider; Brian T Chait; J P Tam
Two-step selective formation of three disulfide bridges in the synthesis of the C-terminal epidermal growth factor-like domain in human blood coagulation factor IX.
Protein science : a publication of the Protein Society 1994;3(8):1267-75.
1994: H Yanase; Sean M Cahill; J J Martin de Llano; Lois R Manning; K Schneider; Brian T Chait; Kim Vandegriff; Robert M Winslow; James M Manning
Properties of a recombinant human hemoglobin with aspartic acid 99(beta), an important intersubunit contact site, substituted by lysine.
Protein science : a publication of the Protein Society 1994;3(8):1213-23.
1994: Photini Sinnis; P Clavijo; D Fenyö; Brian T Chait; Carla Hand; Victor Nussenzweig
Structural and functional properties of region II-plus of the malaria circumsporozoite protein.
The Journal of experimental medicine 1994;180(1):297-306.
1994: Brian T Chait
Mass spectrometry--a useful tool for the protein X-ray crystallographer and NMR spectroscopist.
Structure (London, England : 1993) 1994;2(6):465-7.
1994: W Zhang; Andrew J Czernik; T Yungwirth; R Aebersold; Brian T Chait
Matrix-assisted laser desorption mass spectrometric peptide mapping of proteins separated by two-dimensional gel electrophoresis: determination of phosphorylation in synapsin I.
Protein science : a publication of the Protein Society 1994;3(4):677-86.
1994: G Carmel; B Leichus; Xiaodong Cheng; S D Patterson; U Mirza; Brian T Chait; Jeffrey Kuret
Expression, purification, crystallization, and preliminary x-ray analysis of casein kinase-1 from Schizosaccharomyces pombe.
The Journal of biological chemistry 1994;269(10):7304-9.
1994: Rong Wang; Brian T Chait
High-accuracy mass measurement as a tool for studying proteins.
Current opinion in biotechnology 1994;5(1):77-84.
1994: M J Rao; K Schneider; Brian T Chait; T L Chao; H Keller; S Anderson; Belur N Manjula; R Kumar; Seetharama A Acharya
Recombinant hemoglobin A produced in transgenic swine: structural equivalence with human hemoglobin A.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):695-700.
1993: J J Martin de Llano; W Jones; K Schneider; Brian T Chait; James M Manning; G Rodgers; L J Benjamin; B Weksler
Biochemical and functional properties of recombinant human sickle hemoglobin expressed in yeast.
The Journal of biological chemistry 1993;268(36):27004-11.
1993: Brian T Chait; Rong Wang; Ronald C Beavis; S B Kent
Protein ladder sequencing.
Science (New York, N.Y.) 1993;262(5130):89-92.
1993: Ales Vancura; A O'Connor; S D Patterson; U Mirza; Brian T Chait; Jeffrey Kuret
Isolation and properties of YCK2, a Saccharomyces cerevisiae homolog of casein kinase-1.
Archives of biochemistry and biophysics 1993;305(1):47-53.
1993: D W Ownby; H Zhu; K Schneider; R C Beavis; Brian T Chait; Austen F Riggs
The extracellular hemoglobin of the earthworm, Lumbricus terrestris. Determination of subunit stoichiometry.
The Journal of biological chemistry 1993;268(18):13539-47.
1993: David A Harris; Mary T Huber; P van Dijken; Show-Ling Shyng; Brian T Chait; R Wang
Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.
Biochemistry 1993;32(4):1009-16.
1993: U A Mirza; Steven Cohen; Brian T Chait
Heat-induced conformational changes in proteins studied by electrospray ionization mass spectrometry.
Analytical chemistry 1993;65(1):1-6.
1992: J S Lindsey; T Chaudhary; Brian T Chait
252Cf plasma desorption mass spectrometry in the synthesis of porphyrin model systems.
Analytical chemistry 1992;64(22):2804-14.
1992: Ameurfina D Santos; Julita S Imperial; T Chaudhary; R C Beavis; Brian T Chait; J P Hunsperger; Baldomero M Olivera; Michael E Adams; David R Hillyard
Heterodimeric structure of the spider toxin omega-agatoxin IA revealed by precursor analysis and mass spectrometry.
The Journal of biological chemistry 1992;267(29):20701-5.
1992: Brian T Chait; S B Kent
Weighing naked proteins: practical, high-accuracy mass measurement of peptides and proteins.
Science (New York, N.Y.) 1992;257(5078):1885-94.
1992: A E Stewart; Simona Raffioni; T Chaudhary; Brian T Chait; P Luporini; Ralph A Bradshaw
The disulfide bond pairing of the pheromones Er-1 and Er-2 of the ciliated protozoan Euplotes raikovi.
Protein science : a publication of the Protein Society 1992;1(6):777-85.
1992: Simona Raffioni; Cristina Miceli; A Vallesi; S K Chowdhury; Brian T Chait; P Luporini; Ralph A Bradshaw
Primary structure of Euplotes raikovi pheromones: comparison of five sequences of pheromones from cells with variable mating interactions.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2071-5.
1991: Franz Hillenkamp; Michael Karas; R C Beavis; Brian T Chait
Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers.
Analytical chemistry 1991;63(24):1193A-1203A.
1991: P Löw; Gustav Dallner; S Mayor; S Cohen; Brian T Chait; Anant K Menon
The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene residues.
The Journal of biological chemistry 1991;266(29):19250-7.
1991: S K Chowdhury; Brian T Chait
Method for the electrospray ionization of highly conductive aqueous solutions.
Analytical chemistry 1991;63(15):1660-4.
1991: S Aduru; Brian T Chait
Californium-252 plasma desorption mass spectrometry of oligosaccharides and glycoconjugates: control of ionization and fragmentation.
Analytical chemistry 1991;63(15):1621-5.
1991: Lois R Manning; S Morgan; Ronald C Beavis; Brian T Chait; James M Manning; John R Hess; M Cross; D L Currell; M A Marini; Robert M Winslow
Preparation, properties, and plasma retention of human hemoglobin derivatives: comparison of uncrosslinked carboxymethylated hemoglobin with crosslinked tetrameric hemoglobin.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3329-33.
1991: D E Goldberg; A F Slater; Ronald C Beavis; Brian T Chait; Anthony Cerami; G B Henderson
Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease.
The Journal of experimental medicine 1991;173(4):961-9.
1991: V Katta; Brian T Chait
Conformational changes in proteins probed by hydrogen-exchange electrospray-ionization mass spectrometry.
Rapid communications in mass spectrometry : RCM 1991;5(4):214-7.
1991: V Katta; S K Chowdhury; Brian T Chait
Use of a single-quadrupole mass spectrometer for collision-induced dissociation studies of multiply charged peptide ions produced by electrospray ionization.
Analytical chemistry 1991;63(2):174-8.
1990: S K Chowdhury; Brian T Chait
Analysis of mixtures of closely related forms of bovine trypsin by electrospray ionization mass spectrometry: use of charge state distributions to resolve ions of the different forms.
Biochemical and biophysical research communications 1990;173(3):927-31.
1990: Ronald C Beavis; Brian T Chait
High-accuracy molecular mass determination of proteins using matrix-assisted laser desorption mass spectrometry.
Analytical chemistry 1990;62(17):1836-40.
1990: Ronald C Beavis; Brian T Chait
Rapid, sensitive analysis of protein mixtures by mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6873-7.
1990: Te Piao King; D Moran; D F Wang; L Kochoumian; Brian T Chait
Structural studies of a hornet venom allergen antigen 5, Dol m V and its sequence similarity with other proteins.
Protein sequences & data analysis 1990;3(3):263-6.
1990: J Buck; G Ritter; L Dannecker; V Katta; Steven Cohen; Brian T Chait; U Hämmerling
Retinol is essential for growth of activated human B cells.
The Journal of experimental medicine 1990;171(5):1613-24.
1990: S K Chowdhury; V Katta; Brian T Chait
Electrospray ionization mass spectrometric peptide mapping: a rapid, sensitive technique for protein structure analysis.
Biochemical and biophysical research communications 1990;167(2):686-92.
1990: S K Chowdhury; V Katta; Brian T Chait
An electrospray-ionization mass spectrometer with new features.
Rapid communications in mass spectrometry : RCM 1990;4(3):81-7.
1990: Susan Pollak; S Halpine; Brian T Chait; Steven Birken
High resolution high performance liquid chromatography fingerprinting of purified human chorionic gonadotropin demonstrates that oxidation is a cause of hormone heterogeneity.
Endocrinology 1990;126(1):199-208.
1989: Ronald C Beavis; Brian T Chait
Matrix-assisted laser-desorption mass spectrometry using 355 nm radiation.
Rapid communications in mass spectrometry : RCM 1989;3(12):436-9.
1989: Ronald C Beavis; Brian T Chait
Cinnamic acid derivatives as matrices for ultraviolet laser desorption mass spectrometry of proteins.
Rapid communications in mass spectrometry : RCM 1989;3(12):432-5.
1989: Y Ito; Jan L Breslow; Brian T Chait
Apolipoprotein C-III0 lacks carbohydrate residues: use of mass spectrometry to study apolipoprotein structure.
Journal of lipid research 1989;30(11):1781-7.
1989: David D Woo; I Clark-Lewis; Brian T Chait; S B Kent
Chemical synthesis in protein engineering: total synthesis, purification and covalent structural characterization of a mitogenic protein, human transforming growth factor-alpha.
Protein engineering 1989;3(1):29-37.
1989: C J Wallace; P Mascagni; Brian T Chait; J F Collawn; Yvonne Paterson; A E Proudfoot; S B Kent
Substitutions engineered by chemical synthesis at three conserved sites in mitochondrial cytochrome c. Thermodynamic and functional consequences.
The Journal of biological chemistry 1989;264(26):15199-209.
1989: K M Khandke; T Fairwell; Brian T Chait; Belur N Manjula
Influence of ions on cyclization of the amino terminal glutamine residues of tryptic peptides of streptococcal PepM49 protein. Resolution of cyclized peptides by HPLC and characterization by mass spectrometry.
International journal of peptide and protein research 1989;34(2):118-23.
1989: S K Chowdhury; Brian T Chait
A mass spectrometric technique for detecting and identifying by-products in the synthesis of peptides.
Analytical biochemistry 1989;180(2):387-95.
1989: Ronald C Beavis; Brian T Chait
Factors affecting the ultraviolet laser desorption of proteins.
Rapid communications in mass spectrometry : RCM 1989;3(7):233-7.
1989: S Burman; D Wellner; Brian T Chait; T Chaudhary; Esther Breslow
Complete assignment of neurophysin disulfides indicates pairing in two separate domains.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):429-33.
1988: Simona Raffioni; P Luporini; Brian T Chait; S S Disper; Ralph A Bradshaw
Primary structure of the mating pheromone Er-1 of the ciliate Euplotes raikovi.
The Journal of biological chemistry 1988;263(34):18152-9.
1988: RB Merrifield; J Singer; Brian T Chait
Mass spectrometric evaluation of synthetic peptides for deletions and insertions.
Analytical biochemistry 1988;174(2):399-414.
1988: K Furukawa; Brian T Chait; K O Lloyd
Identification of N-glycolylneuraminic acid-containing gangliosides of cat and sheep erythrocytes. 252Cf fission fragment ionization mass spectrometry in the analysis of glycosphingolipids.
The Journal of biological chemistry 1988;263(29):14939-47.
1988: Werner Ens; D E Main; Kenneth G Standing; Brian T Chait
Comparison of relative quasi-molecular ion yields for 8-keV ion and 252Cf fission fragment bombardment.
Analytical chemistry 1988;60(15):1494-8.
1988: S Burman; Esther Breslow; Brian T Chait; T Chaudhary
Application of high-performance liquid chromatography in neurophysin disulfide assignment.
Journal of chromatography 1988;443():285-98.
1988: J F Garcia-Bustos; Brian T Chait; Alexander Tomasz
Altered peptidoglycan structure in a pneumococcal transformant resistant to penicillin.
Journal of bacteriology 1988;170(5):2143-7.
1987: J F Garcia-Bustos; Brian T Chait; Alexander Tomasz
Structure of the peptide network of pneumococcal peptidoglycan.
The Journal of biological chemistry 1987;262(32):15400-5.
1987: F Lafortune; R Beavis; X Tang; Kenneth G Standing; Brian T Chait
Narrowing the gap between keV and fission fragment secondary ion yields with nitrocellulose.
Rapid communications in mass spectrometry : RCM 1987;1(7-8):114-6.
1987: S Burman; Esther Breslow; Brian T Chait; T Chaudhary
Partial assignment of disulfide pairs in neurophysins.
Biochemical and biophysical research communications 1987;148(2):827-33.
1987: J A Leo; E R Williams; I J Amster; J J Furlong; B H Wang; Fred W McLafferty; Brian T Chait; F H Field
Californium-252 plasma desorption with Fourier transform mass spectrometry.
Analytical chemistry 1987;59(14):1880-2.
1986: R Bucala; P C Ulrich; Brian T Chait; F A Bencsath; A Cerami
Structure of lysine adducts with 16 alpha-hydroxyestrone and cortisol.
Journal of steroid biochemistry 1986;25(1):127-33.
1986: Jane Gale; B L Bentz; Brian T Chait; F H Field; Robert J Cotter
Reduction in liquid secondary ion mass spectrometry. Comparison of the fission fragment and liquid secondary ion mass spectra of organic dyestuffs.
Analytical chemistry 1986;58(6):1070-6.
1986: Brian T Chait; F H Field
A rapid, sensitive mass spectrometric method for investigating microscale chemical reactions of surface adsorbed peptides and proteins.
Biochemical and biophysical research communications 1986;134(1):420-6.
1985: Alan H Fairlamb; P Blackburn; P Ulrich; Brian T Chait; A Cerami
Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids.
Science (New York, N.Y.) 1985;227(4693):1485-7.
1984: Andrew P Feinberg; P M Vidal; J J Fox; KA Watanabe; Moon Woo Chun; F H Field; A Bencsath; Brian T Chait; F S Philips
Structures of metabolites isolated from urine of mice treated with the antiviral agent, 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-methyluracil.
Drug metabolism and disposition: the biological fate of chemicals 1984;12(6):784-6.