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Jorge Reis-Filho

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Disorders

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Oligonucleotide Array Sequence Analysis

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Paul M Wilkerson; Jorge S Reis-Filho
The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.
Daniel Wetterskog; Paul M Wilkerson; Silvana Di Palma; Roger A'Hern; Mattias K Andersson; Karen Fritchie; Zoran Gatalica; Arnaud Gauthier; Maryou B K Lambros; Rachael Natrajan; Daniel N Rodrigues; Brian P Rubin; Sami Shousha; Göran Stenman; Chantal Töpfer; Anne Vincent-Salomon; Vesna Vukovic; Britta Weigelt; Jorge S Reis-Filho
Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations.
Britta Weigelt; Jorge S Reis-Filho
Activating mutations in HER2: neu opportunities and neu challenges.

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All Publications

2013: Paul M Wilkerson; Jorge S Reis-Filho
The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.
Genes, chromosomes & cancer 2013;52(4):333-55.
2013: Daniel Wetterskog; Paul M Wilkerson; Silvana Di Palma; Roger A'Hern; Mattias K Andersson; Karen Fritchie; Zoran Gatalica; Arnaud Gauthier; Maryou B K Lambros; Rachael Natrajan; Daniel N Rodrigues; Brian P Rubin; Sami Shousha; Göran Stenman; Chantal Töpfer; Anne Vincent-Salomon; Vesna Vukovic; Britta Weigelt; Jorge S Reis-Filho
Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations.
Histopathology 2013;62(4):543-50.
2013: Britta Weigelt; Jorge S Reis-Filho
Activating mutations in HER2: neu opportunities and neu challenges.
Cancer discovery 2013;3(2):145-7.
2013: Ivana Kurelac; Maryou B K Lambros; Alan MacKay; Antonio Melcarne; Luca Morandi; Isabella Morra; Jorge S Reis-Filho; Giovanni Tallini; Marcella Attimonelli; Francesco Maria Calabrese; Claudio Ceccarelli; Giovanna Cenacchi; Erica Di Cesare; Giuseppe Gasparre
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Human molecular genetics 2013;22(2):226-38.
2012: S Guiu; B T Hennessy; S Loi; S Michiels; F André; J Cortes; C Denkert; A Di Leo; T Sorlie; C Sotiriou; N Turner; M Van de Vijver; G Viale; Jorge S Reis-Filho
Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(12):2997-3006.
2012: Britta Weigelt; Jorge S Reis-Filho; C Swanton
Genomic analyses to select patients for adjuvant chemotherapy: trials and tribulations.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23 Suppl 10():x211-8.
2012: Anneleen Daemen; Jessica R Frankum; Joe W Gray; Obi L Griffith; Lakshmi R Jakkula; James E Korkola; Christopher J Lord; Rachael Natrajan; Jorge S Reis-Filho; Paul T Spellman; Alan Ashworth; Rachel Brough; Nicholas J Wang; Denise M Wolf; Laura J van't Veer
Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib.
Breast cancer research and treatment 2012;135(2):505-17.
2012: Emad A Rakha; Ian O Ellis; Zsolt Hodi; Andrew H S Lee; Joseph Roberts; Nadia M Villena Salinas; Jorge S Reis-Filho
Low-estrogen receptor-positive breast cancer: the impact of tissue sampling, choice of antibody, and molecular subtyping.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(23):2929-30; author reply 2931.
2012: Charlotte K Y Ng; Helen N Pemberton; Jorge S Reis-Filho
Breast cancer intratumor genetic heterogeneity: causes and implications.
Expert review of anticancer therapy 2012;12(8):1021-32.
2012: Simon J Furney; Jarle Hakas; Meenhard Herlyn; Iwanka Kozarewa; Maryou B K Lambros; christopher Lord; Alan Mackay; Costas Mitsopoulos; Hiroshi Murata; Jorge S Reis-Filho; Gerda Ricken; Samra Turajlic; Marketa Zvelebil; Alan Ashworth; Kerry Fenwick; Richard Marais
Genomic characterisation of acral melanoma cell lines.
Pigment cell & melanoma research 2012;25(4):488-92.
2012: Philip J Stephens; Patrick S Tarpey; Jon Teague; Benita Tan Kiat Tee; Gilles Thomas; Gulisa Turashvili; Andrew Tutt; Marc van de Vijver; Peter Van Loo; Laura van 't Veer; Ignacio Varela; Ana Cristina Vargas; David C Wedge; Lucy R Yates; Samuel A J R Aparicio; David Beare; Graham R Bignell; Anne-Lise Børresen-Dale; Sandrine Boyault; Annegien Broeks; Adam Butler; Carlos Caldas; Peter J Campbell; Michael Spencer Chapman; Angela Cheverton; Suet-Feung Chin; Helen Davies; Christine Desmedt; Douglas Easton; Aquila Fatima; John Foekens; P Andrew Futreal; John Gamble; Chris Greenman; Jonathan Hinton; Bernice Wong Huimin; Alagu Jayakumar; Mingming Jia; David Jones; Sunil R Lakhani; Anita Langerød; Calli Latimer; King Wai Lau; Ming Ta Michael Lee; Odette Mariani; John Martens; Sancha Martin; David J McBride; Stuart McLaren; Andrew Menzies; Penelope Miron; Laura Mudie; Serena Nik-Zainal; Elli Papaemmanuil; Roland Rad; Keiran Raine; Jorge S Reis-Filho; Andrea L Richardson; Anne Vincent Salomon; Chen-Yang Shen; Christos Sotiriou; Michael R Stratton
The landscape of cancer genes and mutational processes in breast cancer.
Nature 2012;486(7403):400-4.
2012: Felipe C Geyer; Ibrahim Khalifeh; Magali Lacroix-Triki; Maryou B K Lambros; Alan Mackay; Caterina Marchiò; Rachael Natrajan; Sandra Orru; Neill Patani; Anna Sapino; Fernando C Schmitt; Nour Sneige; Britta Weigelt; Jelle Wesseling; Constance Albarracin; Pierre-Emmanuel Colombo; Arnaud Gauthier; Jorge S Reis-Filho
Molecular evidence in support of the neoplastic and precursor nature of microglandular adenosis.
Histopathology 2012;60(6B):E115-30.
2012: Rachael Natrajan; Vidya Pawar; Tatiana Popova; Daniel-Nava Rodruigues; Dominique Stoppa-Lyonnet; Charles Swanton; Samra Turajlic; Petra van der Groep; Paulus van Diest; Anne Vincent-Salomon; Patty Wai; Britta Weigelt; Paul M Wilkerson; Roger A'hern; Alan Ashworth; Jason Carroll; Olivier Delattre; Ian O Ellis; Adriana C Flora; William D Foulkes; Simon J Furney; Andrew R Green; Anita Grigoriadis; Marc Henri Stern; Iwanka Kozarewa; Maryou B Lambros; Christopher J Lord; Alan Mackay; Elodie Manie; Richard Marais; Odette Mariani; Simon McDade; Jorge S Reis-Filho
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
The Journal of pathology 2012;227(1):29-41.
2012: Lucia Hernandez; Maryou B K Lambros; Alan Mackay; Caterina Marchiò; Rachael Natrajan; Jose Palacios; Vidya Pawar; Roger A'hern; Cecilia Cabral; Adriana Campion-Flora; Arnaud Gauthier; Daniel Nava Rodrigues; Britta Weigelt; Paul M Wilkerson; Jorge S Reis-Filho
Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection.
The Journal of pathology 2012;227(1):42-52.
2012: Nicholas C Turner; Jorge S Reis-Filho
Genetic heterogeneity and cancer drug resistance.
The lancet oncology 2012;13(4):e178-85.
2012: Rachel Brough; christopher Lord; Rachael Natrajan; Jorge S Reis-Filho; Radost Vatcheva; Ilirjana Bajrami; Alan Ashworth
APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.
The EMBO journal 2012;31(5):1160-76.
2012: Samra Turajlic; Marketa Zvelebil; Costas Mitsopoulos; Jorge S Reis-Filho; Gordon Stamp; Meirion Thomas; Alan Ashworth; Simon J Furney; Felipe C Geyer; Jarle Hakas; Iwanka Kozarewa; Maryou B K Lambros; James Larkin; christopher Lord; Alan Mackay; Richard Marais
Whole genome sequencing of matched primary and metastatic acral melanomas.
Genome research 2012;22(2):196-207.
2012: Joel Rae; Jorge S Reis-Filho; Dorothy C Bennett; Nathalie Dhomen; Amaya Viros; Robert Hayward; B Jack Longley; Richard Marais
(V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
The Journal of investigative dermatology 2012;132(2):488-91.
2012: David Sarrio; Chris K Franklin; Alan Mackay; Jorge S Reis-Filho; Clare M Isacke
Epithelial and mesenchymal subpopulations within normal basal breast cell lines exhibit distinct stem cell/progenitor properties.
Stem cells (Dayton, Ohio) 2012;30(2):292-303.
2012: Roberto Tonelli; Andrea Tortori; Linda J Valentijn; Zoë S Walters; Brenda Summersgill; Kathryn R Taylor; Khin Thway; Valentina Ambrosini; Annalisa Astolfi; Ryan Bishop; Consuelo Camerin; Giorgio Cantelli-Forti; Roberto Corradini; Korinne Di Leo; Andrea Faccini; Stefano Fanti; Serena Formica; Monica Franzoni; Patrizia Hrelia; Ivo Leuschner; Rosangela Marchelli; Alan McIntyre; Edoardo Missiaglia; Cristina Nanni; Andrea Pession; Stefania Purgato; Jorge S Reis-Filho; Jane Renshaw; Joanna Selfe; Salvatore Serravalle; Janet Shipley
Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):796-807.
2012: Raphaëlle Duprez; Arnaud Gauthier; Roger A' Hern; Magali Lacroix-Triki; Maryou B K Lambros; Gaëtan Macgrogan; Alan Mackay; Patrick Michenet; Rachael Natrajan; Vidya Pawar; Anne Vincent-Salomon; Eric Ward; Britta Weigelt; Paul M Wilkerson; Flavie Arbion; Pierre-Emanuel Colombo; Frances Daley; Jorge S Reis-Filho
Immunophenotypic and genomic characterization of papillary carcinomas of the breast.
The Journal of pathology 2012;226(3):427-41.
2012: Felipe C Geyer; Ivana Kurelac; Maryou B K Lambros; Maria A Lopez-Garcia; Alan Mackay; Rachael Natrajan; Moira Ragazzi; Jorge S Reis-Filho; Alan Ashworth; Dario de Biase; Vincenzo Eusebi; Giuseppe Gasparre; Giovanni Tallini
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology.
Breast cancer research and treatment 2012;132(1):15-28.
2012: Fei Su; James L Troy; Kerstin Trunzer; Amaya Viros; Qiongqing Wang; Bernice Matusow; Hong Yang; Alfonso Zambon; Chao Zhang; Luc Andries; Gideon Bollag; Elizabeth A Burton; Paul B Chapman; Bartosz Chmielowski; Nathalie Dhomen; Keith T Flaherty; Felipe Geyer; Rene Gonzalez; Gaston Habets; Julie S Hang; Robert Hayward; Holly Hilton; Thomas E Hutson; Andrew K Joe; Damien Kee; Min Jung Kim; Mark Kockx; Xiangju Kong; Richard C Koya; Maryou Lambros; Richard J Lee; Brian Lestini; Roger S Lo; Yan Ma; Matthew Martin; Grant A McArthur; Carla Milagre; Stephen Mok; Hoa Nguyen; Dan Niculescu-Duvaz; Ion Niculescu-Duvaz; Johannes Noe; Keith B Nolop; Nicholas J Otte; Natasha Preece; Igor Puzanov; Jorge S Reis-Filho; Antoni Ribas; Lídia Robert; Jeffrey A Sosman; Olivia Spleiss; Caroline J Springer; Richard Marais
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
The New England journal of medicine 2012;366(3):207-15.
2012: Anita Grigoriadis; Alan Mackay; Rachel Natrajan; Elodie Noel; Jorge S Reis-Filho; Jessica Frankum; Pei Jun Wu; Andrew Tutt
Molecular characterisation of cell line models for triple-negative breast cancers.
BMC genomics 2012;13():619.
2012: Charlotte Ng; Anita Grigoriadis; Britta Weigelt; Jorge S Reis-Filho
Prognostic signatures in breast cancer: correlation does not imply causation.
Breast cancer research : BCR 2012;14(3):313.
2012: Rachael Natrajan; Jose Palacios; Monica Arnedos; Felipe C Geyer; Hugo Horlings; Bas Kreike; Maryou B K Lambros; Anita Langerød; Alan Mackay; Fabien Reyal; Kai-Keen Shiu; Marc J van de Vijver; Britta Weigelt; Daniel Wetterskog; Paul M Wilkerson; Jorge S Reis-Filho
Functional characterization of the 19q12 amplicon in grade III breast cancers.
Breast cancer research : BCR 2012;14(2):R53.
2012: Mohammed Aleskandarany; Fabricio F Barros; Ahmed A Benhasouna; Ian O Ellis; Andrew R Green; Keith Neal; Jorge S Reis-Filho; Emad A Rakha
Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer.
Breast cancer research : BCR 2012;14(1):R3.
2012: Felipe C Geyer; Britta Weigelt; Daniel N Rodrigues; Jorge S Reis-Filho
Molecular classification of estrogen receptor-positive/luminal breast cancers.
Advances in anatomic pathology 2012;19(1):39-53.
2012: Daniel Wetterskog; Roger A'Hern; Maria C Cabral; Zoran Gatalica; Arnaud Gauthier; Felipe C Geyer; Maryou B K Lambros; Maria Angeles Lopez-Garcia; Alan Mackay; Fernanda Milanezi; Rachael Natrajan; Nicholas Orr; Jose Palacios; Jorge S Reis-Filho; Kai-Keen Shiu; Sami Shousha; Britta Weigelt
Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers.
The Journal of pathology 2012;226(1):84-96.
2012: Neill Patani; Konstantin J Dedes; Lesley-Ann Martin; Felipe C Geyer; Mitch Dowsett; Rachael Natrajan; Eric Ward; Maryou B Lambros; Jorge S Reis-Filho
Non-existence of caveolin-1 gene mutations in human breast cancer.
Breast cancer research and treatment 2012;131(1):307-10.
2012: Neill Patani; Jorge S Reis-Filho; Lesley-Ann Martin; Mitch Dowsett
The role of caveolin-1 in human breast cancer.
Breast cancer research and treatment 2012;131(1):1-15.
2012: Britta Weigelt; Alan Ashworth; Lajos Pusztai; Jorge S Reis-Filho
Challenges translating breast cancer gene signatures into the clinic.
Nature reviews. Clinical oncology 2012;9(1):58-64.
2011: Dan R Robinson; Michael Sabel; Sunita Shankar; Javed Siddiqui; Yi-Mi Wu; Irfan A Asangani; Bushra Ateeq; Xuhong Cao; Thomas J Giordano; Catherine S Grasso; Matthew Iyer; Xiaojun Jing; Shanker Kalyana-Sundaram; Celina G Kleer; Chandan Kumar; Maryou B Lambros; Robert J Lonigro; Christopher A. Maher; Rohit Mehra; Rachael Natrajan; Nallasivam Palanisamy; Michael Quist; Jorge S Reis-Filho; Arul M Chinnaiyan
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Nature medicine 2011;17(12):1646-51.
2011: Jorge S Reis-Filho; Lajos Pusztai
Gene expression profiling in breast cancer: classification, prognostication, and prediction.
Lancet 2011;378(9805):1812-23.
2011: Cathy B Moelans; Jorge S Reis-Filho; Paulus van Diest
Implications of rarity of chromosome 17 polysomy in breast cancer.
The lancet oncology 2011;12(12):1087-9.
2011: N Rajan; Jorge S Reis-Filho; Maya Sieber-Blum; J Burn; O Clewes; R Elliott; J Langtry; C J Lord; A Mackay; A Ashworth
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.
Oncogene 2011;30(41):4243-60.
2011: Maryou B K Lambros; Mirja Laschet; Marthe Mansour; Susanne Muller; Rachael Natrajan; Beatrice Oelze; Nicholas Orr; Neill Patani; Vidya Pawar; Radost Vatcheva; Paul M Wilkerson; Jorge S Reis-Filho
High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform.
Laboratory investigation; a journal of technical methods and pathology 2011;91(10):1491-501.
2011: Chey Loveday; Zosia Miedzybrodzka; Patrick J Morrison; Joan Paterson; Mary Porteous; Emma Ramsay; Jorge S Reis-Filho; Anthony Renwick; Mark T Rogers; Elise Ruark; Sheila Seal; Susan Shanley; Katie Snape; Clare Turnbull; Lisa Walker; Margaret Warren-Perry; Julian W Adlard; Antonis C Antoniou; Alan Ashworth; Julian Barwell; Jonathan Berg; Georgina Bowden; Angela F Brady; Carole Brewer; Glen Brice; Cyril Chapman; Jackie Cook; Rosemarie Davidson; Alan Donaldson; Fiona Douglas; Diana Eccles; D Gareth Evans; Jessica R Frankum; Lynn Greenhalgh; Alex Henderson; Deborah Hughes; Louise Izatt; Bolot Kalmyrzaev; Ajith Kumar; Fiona Lalloo; Christopher J Lord; Nazneen Rahman
Germline mutations in RAD51D confer susceptibility to ovarian cancer.
Nature genetics 2011;43(9):879-82.
2011: Paul M Wilkerson; Daniel Wetterskog; Alan Ashworth; Konstantin Dedes; Jessica Frankum; Maryou B K Lambros; christopher Lord; Alan Mackay; Marthe Mansour; Rachael Natrajan; Jorge S Reis-Filho
Functional characterization of EMSY gene amplification in human cancers.
The Journal of pathology 2011;225(1):29-42.
2011: Neill Patani; Violetta Barbashina; Arnaud Gauthier; Maryou B K Lambros; Alan Mackay; Marthe Mansour; Jorge S Reis-Filho
Direct evidence for concurrent morphological and genetic heterogeneity in an invasive ductal carcinoma of triple-negative phenotype.
Journal of clinical pathology 2011;64(9):822-8.
2011: Munir R Tanas; Sharon W Weiss; Rob B West; Marketa Zvelebil; Mark A Rubin; Andrea Sboner; Raf Sciot; Alan Ashworth; Maria Debiec-Rychter; Michele R Erickson-Johnson; Kerry Fenwick; John Flanagan; Mark B Gerstein; Philip J Hanwright; Jessica Hespelt; Benjamin L Hoch; Alexander J Lazar; christopher Lord; Yuling Luo; Costas Mitsopoulos; Rachael Natrajan; Andre M Oliveira; Jorge S Reis-Filho; Brian P Rubin
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma.
Science translational medicine 2011;3(98):98ra82.
2011: Rachel Sharpe; Jonathan C Welti; Alan Ashworth; Maria T Herrera-Abreu; Damian Johnson; Alan Mackay; Rachael Natrajan; Alex Pearson; Jorge S Reis-Filho; Andrew R Reynolds; Nicholas C Turner
FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(16):5275-86.
2011: Rachel Brough; Maria Antonietta Cerone; Sara Costa-Cabral; Konstantin Dedes; Jessica R Frankum; Maryou B K Lambros; Spiros Linardopoulos; christopher Lord; Alan Mackay; Ana M Mendes-Pereira; Rachael Natrajan; Rumana Rafiq; Teeara Rawjee; Jorge S Reis-Filho; Rachel Sharpe; Kai-Keen Shiu; David Sims; Nicholas C Turner; Daniel Wetterskog; Amar S Ahmad; Ilirjana Bajrami; Alan Ashworth
Functional viability profiles of breast cancer.
Cancer discovery 2011;1(3):260-73.
2011: Daniela Hungermann; Burkhard Brandt; Horst Buerger; Rachael Natrajan; Kathrin Poos; Jorge S Reis-Filho; Hartmut Schmidt; Nicola Tidow; Eberhard Korsching
Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer.
The Journal of pathology 2011;224(4):517-28.
2011: David H Nguyen; Hellen A Oketch-Rabah; Irineu Illa-Bochaca; Felipe C Geyer; Jorge S Reis-Filho; Jian-Hua Mao; Shraddha A Ravani; Jiri Zavadil; Alexander D Borowsky; D Joseph Jerry; Karen A Dunphy; Jae Hong Seo; Sandra Z Haslam; Daniel Medina; Mary Helen Barcellos-Hoff
Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type.
Cancer cell 2011;19(5):640-51.
2011: Rachael Natrajan; Jorge S Reis-Filho
Next-generation sequencing applied to molecular diagnostics.
Expert review of molecular diagnostics 2011;11(4):425-44.
2011: Konstantin Dedes; Daniel Wetterskog; Alan Ashworth; Stan B Kaye; Jorge S Reis-Filho
Emerging therapeutic targets in endometrial cancer.
Nature reviews. Clinical oncology 2011;8(5):261-71.
2011: Alan Mackay; Britta Weigelt; Anita Grigoriadis; Bas Kreike; Rachael Natrajan; Roger A'Hern; David S P Tan; Mitch Dowsett; Alan Ashworth; Jorge S Reis-Filho
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Journal of the National Cancer Institute 2011;103(8):662-73.
2011: Konstantin Dedes; Paul M Wilkerson; Daniel Wetterskog; Britta Weigelt; Alan Ashworth; Jorge S Reis-Filho
Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.
Cell cycle (Georgetown, Tex.) 2011;10(8):1192-9.
2011: Alan Ashworth; Christopher J Lord; Jorge S Reis-Filho
Genetic interactions in cancer progression and treatment.
Cell 2011;145(1):30-8.
2011: Ana Cristina Vargas; Jorge S Reis-Filho; Sunil R Lakhani
Phenotype-genotype correlation in familial breast cancer.
Journal of mammary gland biology and neoplasia 2011;16(1):27-40.
2011: David S P Tan; Marjan Iravani; W Glenn McCluggage; Maryou B K Lambros; Fernanda Milanezi; Alan Mackay; Charles Gourley; Felipe C Geyer; Radost Vatcheva; Joanne Millar; Karen Thomas; Rachael Natrajan; Kay Savage; Kerry Fenwick; Alistair Williams; Charles Jameson; Mona El-Bahrawy; Martin E Gore; Hani Gabra; Stanley B Kaye; Alan Ashworth; Jorge S Reis-Filho
Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1521-34.
2011: L A Henry; D A Johnson; D Sarrió; S Lee; P R Quinlan; Tim Crook; A M Thompson; Jorge S Reis-Filho; Clare M Isacke
Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome.
Oncogene 2011;30(9):1046-58.
2011: Fabrice Andre; Lisa M McShane; Stefan Michiels; David F Ransohoff; Douglas G Altman; Jorge S Reis-Filho; Daniel F Hayes; Lajos Pusztai
Biomarker studies: a call for a comprehensive biomarker study registry.
Nature reviews. Clinical oncology 2011;8(3):171-6.
2011: Robin L Jones; Federico Rojo; Roger A'Hern; Nadia Villena; Janine Salter; Josep Maria Corominas; Sonia Servitja; Ian E Smith; Ana Rovira; Jorge S Reis-Filho; Mitchell Dowsett; Joan Albanell
Nuclear NF-κB/p65 expression and response to neoadjuvant chemotherapy in breast cancer.
Journal of clinical pathology 2011;64(2):130-5.
2011: Moira Ragazzi; Dario de Biase; Christine M Betts; Anna Farnedi; Saime Sezgin Ramadan; Giovanni Tallini; Jorge S Reis-Filho; Vincenzo Eusebi
Oncocytic carcinoma of the breast: frequency, morphology and follow-up.
Human pathology 2011;42(2):166-75.
2011: Sunil Badve; David J Dabbs; Stuart J Schnitt; Frederick L Baehner; Thomas Decker; Vincenzo Eusebi; Stephen B Fox; Shu Ichihara; Jocelyne Jacquemier; Sunil R Lakhani; José Palacios; Emad A Rakha; Andrea L Richardson; Fernando C Schmitt; Puay Hoon Tan; Gary M Tse; Britta Weigelt; Ian O Ellis; Jorge S Reis-Filho
Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(2):157-67.
2011: Felipe C Geyer; Magali Lacroix-Triki; Kay Savage; Monica Arnedos; Maryou B K Lambros; Alan Mackay; Rachael Natrajan; Jorge S Reis-Filho
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(2):209-31.
2011: Kevin C H Ha; Jarle Hakas; Iwanka Kozarewa; Emilie Lalonde; Maryou B K Lambros; Lili Li; Chris J Lord; Jacek Majewski; Costas Mitsopoulos; Rachael Natrajan; Jorge S Reis-Filho; Anne Vincent-Salomon; Alan Ashworth; Mark Basik; Luca Cavallone; Kerry Fenwick; William D Foulkes
Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines.
BMC medical genomics 2011;4():75.
2011: Olivia Wansbury; Marketa Zvelebil; Kathryn Davidson; Howard Kendrick; Naoko Kogata; Alan Mackay; Costas Mitsopoulos; Jorge S Reis-Filho; Christiana Ruhrberg; Matthew J Smalley; BA Howard
Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment.
Breast cancer research : BCR 2011;13(4):R79.
2011: Pierre-Emmanuel Colombo; Fernanda Milanezi; Britta Weigelt; Jorge S Reis-Filho
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Breast cancer research : BCR 2011;13(3):212.
2011: Caterina Marchiò; Mitch Dowsett; Jorge S Reis-Filho
Revisiting the technical validation of tumour biomarker assays: how to open a Pandora's box.
BMC medicine 2011;9():41.
2011: Huiling Xu; Max Yan; Yuqian Yan; Michael McKay; Catriona M McNeil; Ewan Ka Millar; Rachael Natrajan; Sandra Alison O'Toole; Jennifer Patra; Robert G Ramsay; Jorge S Reis-Filho; Robert L Sutherland; SM Swagemakers; Jonathan M Tomaszewski; Peter van der Spek; Sandra Verschoor; Stephen B Fox
Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers.
Breast cancer research : BCR 2011;13(1):R9.
2011: Konstantin Dedes; Rachael Natrajan; Maryou B K Lambros; Felipe C Geyer; Maria Angeles Lopez-Garcia; Kay Savage; Robin L Jones; Jorge S Reis-Filho
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer.
European journal of cancer (Oxford, England : 1990) 2011;47(1):138-50.
2010: Thomas Rio Frio; Josée Lavoie; Nancy Hamel; Felipe C Geyer; Yaël B Kushner; David J Novak; Landon Wark; Cristian Capelli; Jorge S Reis-Filho; Sabine Mai; Tomi Pastinen; Marc D Tischkowitz; Victoria A Marcus; William D Foulkes
Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia.
The New England journal of medicine 2010;363(27):2628-37.
2010: Monika Graeser; Afshan McCarthy; christopher Lord; Kay Savage; Margaret Hills; Janine Salter; Nicholas Orr; Marina Parton; Ian E Smith; Jorge S Reis-Filho; Mitch Dowsett; Alan Ashworth; Nicholas C Turner
A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(24):6159-68.
2010: Tarek M A Abdel-Fatah; Des G Powe; Graham Ball; Maria A Lopez-Garcia; Hany O Habashy; Andrew Green; Jorge S Reis-Filho; Ian O Ellis
Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer.
The Journal of pathology 2010;222(4):388-99.
2010: Konstantin Dedes; Maria-Angeles Lopez-Garcia; Felipe C Geyer; Maryou B K Lambros; Kay Savage; Radost Vatcheva; Paul Wilkerson; Daniel Wetterskog; Magali Lacroix-Triki; Rachael Natrajan; Jorge S Reis-Filho
Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study.
Breast cancer research and treatment 2010;124(3):653-66.
2010: William D Foulkes; Ian E Smith; Jorge S Reis-Filho
Triple-negative breast cancer.
The New England journal of medicine 2010;363(20):1938-48.
2010: Magali Lacroix-Triki; Paula H Suarez; Alan Mackay; Maryou B K Lambros; Rachael Natrajan; Kay Savage; Felipe C Geyer; Britta Weigelt; Alan Ashworth; Jorge S Reis-Filho
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type.
The Journal of pathology 2010;222(3):282-98.
2010: Magali Lacroix-Triki; Felipe C Geyer; Maryou B K Lambros; Kay Savage; Ian O Ellis; Andrew H S Lee; Jorge S Reis-Filho
β-catenin/Wnt signalling pathway in fibromatosis, metaplastic carcinomas and phyllodes tumours of the breast.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(11):1438-48.
2010: Rebecca A Burrell; Nicolai Juul; Stephen R Johnston; Jorge S Reis-Filho; Zoltan Szallasi; Charles Swanton
Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer.
Journal of cellular biochemistry 2010;111(4):782-90.
2010: Steven Whittaker; Delphine Ménard; Ruth Kirk; Lesley M Ogilvie; Douglas Hedley; Alfonso Zambon; Filipa Lopes; Natasha Preece; Helen Anuradha Manne; Sareena Rana; Maryou B K Lambros; Jorge S Reis-Filho; Richard Marais; Caroline J Springer
A novel, selective, and efficacious nanomolar pyridopyrazinone inhibitor of V600EBRAF.
Cancer research 2010;70(20):8036-44.
2010: Konstantin Dedes; Daniel Wetterskog; Ana M Mendes-Pereira; Rachael Natrajan; Maryou B K Lambros; Felipe C Geyer; Radost Vatcheva; Kay Savage; Alan Mackay; christopher Lord; Alan Ashworth; Jorge S Reis-Filho
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors.
Science translational medicine 2010;2(53):53ra75.
2010: W Glenn McCluggage; Ian Harley; JP Houghton; Felipe C Geyer; Alan MacKay; Jorge S Reis-Filho
Composite cervical adenocarcinoma composed of adenoma malignum and gastric type adenocarcinoma (dedifferentiated adenoma malignum) in a patient with Peutz Jeghers syndrome.
Journal of clinical pathology 2010;63(10):935-41.
2010: Emad A Rakha; Arjun Patel; Des G Powe; Ahmed Benhasouna; Andrew Green; Maryou B K Lambros; Jorge S Reis-Filho; Ian O Ellis
Clinical and biological significance of E-cadherin protein expression in invasive lobular carcinoma of the breast.
The American journal of surgical pathology 2010;34(10):1472-9.
2010: Maryou B K Lambros; Rachael Natrajan; Felipe C Geyer; Maria A Lopez-Garcia; Konstantin Dedes; Kay Savage; Magali Lacroix-Triki; Robin L Jones; christopher Lord; Spiros Linardopoulos; Alan Ashworth; Jorge S Reis-Filho
PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(10):1334-45.
2010: Gemma Molyneux; Felipe C Geyer; Fiona-Ann Magnay; Afshan McCarthy; Howard Kendrick; Rachael Natrajan; Alan Mackay; Anita Grigoriadis; Andrew Tutt; Alan Ashworth; Jorge S Reis-Filho; Matthew J Smalley
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.
Cell stem cell 2010;7(3):403-17.
2010: Jorge S Reis-Filho; Britta Weigelt; Debora Fumagalli; Christos Sotiriou
Molecular profiling: moving away from tumor philately.
Science translational medicine 2010;2(47):47ps43.
2010: Maria A Lopez-Garcia; Felipe C Geyer; Rachael Natrajan; Bas Kreike; Alan Mackay; Anita Grigoriadis; Jorge S Reis-Filho; Britta Weigelt
Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas.
The Journal of pathology 2010;222(1):64-75.
2010: Magali Lacroix-Triki; Felipe Correa Geyer; Jorge S Reis-Filho
Caveolin-1 P132L mutation in human cancers: 1 CAVeat to be voiced.
The Journal of molecular diagnostics : JMD 2010;12(5):562-5.
2010: Anastasia Constantinidou; Robin L Jones; Jorge S Reis-Filho
Beyond triple-negative breast cancer: the need to define new subtypes.
Expert review of anticancer therapy 2010;10(8):1197-213.
2010: Maria A Lopez-Garcia; Felipe C Geyer; Magali Lacroix-Triki; Caterina Marchió; Jorge S Reis-Filho
Breast cancer precursors revisited: molecular features and progression pathways.
Histopathology 2010;57(2):171-92.
2010: Erika Resetkova; Jorge S Reis-Filho; Rohit K Jain; Rutika Mehta; Mangesh Thorat; Harikrishna Nakshatri; Sunil Badve
Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment.
Breast cancer research and treatment 2010;123(1):97-108.
2010: Carla Milagre; Nathalie Dhomen; Felipe C Geyer; Robert Hayward; Maryou B K Lambros; Jorge S Reis-Filho; Richard Marais
A mouse model of melanoma driven by oncogenic KRAS.
Cancer research 2010;70(13):5549-57.
2010: Felipe C Geyer; Maryou B K Lambros; Rachael Natrajan; Rutika Mehta; Alan Mackay; Kay Savage; Suzanne Parry; Alan Ashworth; Sunil Badve; Jorge S Reis-Filho
Genomic and immunohistochemical analysis of adenosquamous carcinoma of the breast.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(7):951-60.
2010: Kai-Keen Shiu; Rachael Natrajan; Felipe C Geyer; Alan Ashworth; Jorge S Reis-Filho
DNA amplifications in breast cancer: genotypic-phenotypic correlations.
Future oncology (London, England) 2010;6(6):967-84.
2010: Britta Weigelt; Felipe C Geyer; Jorge S Reis-Filho
Histological types of breast cancer: how special are they?
Molecular oncology 2010;4(3):192-208.
2010: William D Foulkes; Jorge S Reis-Filho; Steven A Narod
Tumor size and survival in breast cancer--a reappraisal.
Nature reviews. Clinical oncology 2010;7(6):348-53.
2010: Rachael Natrajan; Britta Weigelt; Alan Mackay; Felipe C Geyer; Anita Grigoriadis; David S P Tan; Chris Jones; Christopher J Lord; Radost Vatcheva; Socorro M Rodriguez-Pinilla; José Palacios; Alan Ashworth; Jorge S Reis-Filho
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers.
Breast cancer research and treatment 2010;121(3):575-89.
2010: Thomas J Hudson; Warwick Anderson; Axel Artez; Anna D Barker; Cindy Bell; Rosa R Bernabé; M K Bhan; Fabien Calvo; Iiro Eerola; Daniela S Gerhard; Alan Guttmacher; Mark Guyer; Fiona M Hemsley; Jennifer L Jennings; David Kerr; Peter Klatt; Patrik Kolar; Jun Kusada; David P Lane; Frank Laplace; Lu Youyong; Gerd Nettekoven; Brad Ozenberger; Jane Peterson; T S Rao; Jacques Remacle; Alan J Schafer; Tatsuhiro Shibata; Michael R Stratton; Joseph G Vockley; Koichi Watanabe; Huanming Yang; Matthew M F Yuen; Bartha M Knoppers; Martin Bobrow; Anne Cambon-Thomsen; Lynn G Dressler; Stephanie O M Dyke; Yann Joly; Kazuto Kato; Karen L Kennedy; Pilar Nicolás; Michael J Parker; Emmanuelle Rial-Sebbag; Carlos M Romeo-Casabona; Kenna M Shaw; Susan Wallace; Georgia L Wiesner; Nikolajs Zeps; Peter Lichter; Andrew V Biankin; Christian Chabannon; Lynda Chin; Bruno Clément; Enrique de Alava; Françoise Degos; Martin L Ferguson; Peter Geary; D Neil Hayes; Thomas J Hudson; Amber L Johns; Arek Kasprzyk; Hidewaki Nakagawa; Robert J Penny; Miguel A Piris; Rajiv Sarin; Aldo Scarpa; Tatsuhiro Shibata; Marc van de Vijver; P Andrew Futreal; Hiroyuki Aburatani; Mónica Bayés; David D L Botwell; Peter J Campbell; Xavier Estivill; Daniela S Gerhard; Sean M Grimmond; Ivo Gut; Martin Hirst; Carlos López-Otín; Partha Majumder; Marco Marra; John D McPherson; Hidewaki Nakagawa; Zemin Ning; Xose S Puente; Yijun Ruan; Tatsuhiro Shibata; Michael R Stratton; Hendrik G Stunnenberg; Harold Swerdlow; Victor E Velculescu; Richard K Wilson; Hong H Xue; Liu Yang; Paul Spellman; Gary D Bader; Paul C Boutros; Peter J Campbell; Paul Flicek; Gad Getz; Roderic Guigó; Guangwu Guo; David Haussler; Simon Heath; Tim J Hubbard; Tao Jiang; Steven M Jones; Qibin Li; Nuria López-Bigas; Ruibang Luo; Lakshmi Muthuswamy; B F Francis Ouellette; John Pearson; Xose S Puente; Victor Quesada; Benjamin J Raphael; Chris Sander; Tatsuhiro Shibata; Terence P Speed; Lincoln D Stein; Joshua M Stuart; Jon W Teague; Yasushi Totoki; Tatsuhiko Tsunoda; Alfonso Valencia; David A Wheeler; Honglong Wu; Shancen Zhao; Guangyu Zhou; Lincoln D Stein; Roderic Guigó; Tim J Hubbard; Yann Joly; Steven M Jones; Arek Kasprzyk; Mark Lathrop; Nuria López-Bigas; B F Francis Ouellette; Paul T Spellman; Jon W Teague; Gilles Thomas; Alfonso Valencia; Teruhiko Yoshida; Karen L Kennedy; Myles Axton; Stephanie O M Dyke; P Andrew Futreal; Daniela S Gerhard; Chris Gunter; Mark Guyer; Thomas J Hudson; John D McPherson; Linda J Miller; Brad Ozenberger; Kenna M Shaw; Arek Kasprzyk; Lincoln D Stein; Junjun Zhang; Syed A Haider; Jianxin Wang; Christina K Yung; Anthony Cross; Yong Liang; Saravanamuttu Gnaneshan; Jonathan Guberman; Jack Hsu; Martin Bobrow; Don R C Chalmers; Karl W Hasel; Yann Joly; Terry S H Kaan; Karen L Kennedy; Bartha M Knoppers; William W Lowrance; Tohru Masui; Pilar Nicolás; Emmanuelle Rial-Sebbag; Laura Lyman Rodriguez; Catherine Vergely; Teruhiko Yoshida; Sean M Grimmond; Andrew V Biankin; David D L Bowtell; Nicole Cloonan; Anna deFazio; James R Eshleman; Dariush Etemadmoghadam; Brooke A Gardiner; James G Kench; Aldo Scarpa; Robert L Sutherland; Margaret A Tempero; Nicola J Waddell; Peter J Wilson; John D McPherson; Steve Gallinger; Ming-Sound Tsao; Patricia A Shaw; Gloria M Petersen; Debabrata Mukhopadhyay; Lynda Chin; Ronald A DePinho; Sarah Thayer; Lakshmi Muthuswamy; Kamran Shazand; Timothy Beck; Michelle Sam; Lee Timms; Vanessa Ballin; Youyong Lu; Jiafu Ji; Xiuqing Zhang; Feng Chen; Xueda Hu; Guangyu Zhou; Qi Yang; Geng Tian; Lianhai Zhang; Xiaofang Xing; Xianghong Li; Zhenggang Zhu; Yingyan Yu; Jun Yu; Huanming Yang; Mark Lathrop; Jörg Tost; Paul Brennan; Ivana Holcatova; David Zaridze; Alvis Brazma; Lars Egevard; Egor Prokhortchouk; Rosamonde Elizabeth Banks; Mathias Uhlén; Anne Cambon-Thomsen; Juris Viksna; Fredrik Ponten; Konstantin Skryabin; Michael R Stratton; P Andrew Futreal; Ewan Birney; Ake Borg; Anne-Lise Børresen-Dale; Carlos Caldas; John A Foekens; Sancha Martin; Jorge S Reis-Filho; Andrea L Richardson; Christos Sotiriou; Hendrik G Stunnenberg; Giles Thoms; Marc van de Vijver; Laura van't Veer; Fabien Calvo; Daniel Birnbaum; Hélène Blanche; Pascal Boucher; Sandrine Boyault; Christian Chabannon; Ivo Gut; Jocelyne D Masson-Jacquemier; Mark Lathrop; Iris Pauporté; Xavier Pivot; Anne Vincent-Salomon; Eric Tabone; Charles Theillet; Gilles Thomas; Jörg Tost; Isabelle Treilleux; Fabien Calvo; Paulette Bioulac-Sage; Bruno Clément; Thomas Decaens; Françoise Degos; Dominique Franco; Ivo Gut; Marta Gut; Simon Heath; Mark Lathrop; Didier Samuel; Gilles Thomas; Jessica Zucman-Rossi; Peter Lichter; Roland Eils; Benedikt Brors; Jan O Korbel; Andrey Korshunov; Pablo Landgraf; Hans Lehrach; Stefan Pfister; Bernhard Radlwimmer; Guido Reifenberger; Michael D Taylor; Christof von Kalle; Partha P Majumder; Rajiv Sarin; T S Rao; M K Bhan; Aldo Scarpa; Paolo Pederzoli; Rita A Lawlor; Massimo Delledonne; Alberto Bardelli; Andrew V Biankin; Sean M Grimmond; Thomas Gress; David S Klimstra; Giuseppe Zamboni; Tatsuhiro Shibata; Yusuke Nakamura; Hidewaki Nakagawa; Jun Kusada; Tatsuhiko Tsunoda; Satoru Miyano; Hiroyuki Aburatani; Kazuto Kato; Akihiro Fujimoto; Teruhiko Yoshida; Elias Campo; Carlos López-Otín; Xavier Estivill; Roderic Guigó; Silvia de Sanjosé; Miguel A Piris; Emili Montserrat; Marcos González-Díaz; Xose S Puente; Pedro Jares; Alfonso Valencia; Heinz Himmelbaue; Victor Quesada; Silvia Bea; Michael R Stratton; P Andrew Futreal; Peter J Campbell; Anne Vincent-Salomon; Andrea L Richardson; Jorge S Reis-Filho; Marc van de Vijver; Gilles Thomas; Jocelyne D Masson-Jacquemier; Samuel Aparicio; Ake Borg; Anne-Lise Børresen-Dale; Carlos Caldas; John A Foekens; Hendrik G Stunnenberg; Laura van't Veer; Douglas F Easton; Paul T Spellman; Sancha Martin; Anna D Barker; Lynda Chin; Francis S Collins; Carolyn Corlies Compton; Martin L Ferguson; Daniela S Gerhard; Gad Getz; Chris Gunter; Alan Guttmacher; Mark Guyer; D Neil Hayes; Eric S Lander; Brad Ozenberger; Robert Penny; Jane Peterson; Chris Sander; Kenna M Shaw; Terence P Speed; Paul T Spellman; Joseph G Vockley; David A Wheeler; Richard K Wilson; Thomas J Hudson; Lynda Chin; Bartha M Knoppers; Eric S Lander; Peter Lichter; Lincoln D Stein; Michael R Stratton; Warwick Anderson; Anna D Barker; Cindy Bell; Martin Bobrow; Wylie Burke; Francis S Collins; Carolyn C Compton; Ronald A DePinho; Douglas F Easton; P Andrew Futreal; Daniela S Gerhard; Anthony R Green; Mark Guyer; Stanley R Hamilton; Tim J Hubbard; Olli P Kallioniemi; Karen L Kennedy; Timothy J Ley; Edison T Liu; Youyong Lu; Partha Majumder; Marco Marra; Brad Ozenberger; Jane Peterson; Alan J Schafer; Paul T Spellman; Hendrik G Stunnenberg; Brandon J Wainwright; Richard K Wilson; Anthony Cros; Brooke B Gardiner; Heinz Himmelbauer; Huanming Yang
International network of cancer genome projects.
Nature 2010;464(7291):993-8.
2010: N Turner; Maryou B K Lambros; H M Horlings; A Pearson; R Sharpe; Rachael Natrajan; F C Geyer; M van Kouwenhove; Bas Kreike; Alan Mackay; Alan Ashworth; Marc J van de Vijver; Jorge S Reis-Filho
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets.
Oncogene 2010;29(14):2013-23.
2010: Britta Weigelt; Alan Mackay; Roger A'hern; Rachael Natrajan; David S P Tan; Mitch Dowsett; Alan Ashworth; Jorge S Reis-Filho
Breast cancer molecular profiling with single sample predictors: a retrospective analysis.
The lancet oncology 2010;11(4):339-49.
2010: Emad A Rakha; Jorge S Reis-Filho; Ian O Ellis
Combinatorial biomarker expression in breast cancer.
Breast cancer research and treatment 2010;120(2):293-308.
2010: Felipe C Geyer; Britta Weigelt; Rachael Natrajan; Maryou B K Lambros; Dario de Biase; Radost Vatcheva; Kay Savage; Alan Mackay; Alan Ashworth; Jorge S Reis-Filho
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas.
The Journal of pathology 2010;220(5):562-73.
2010: Caterina Marchiò; Britta Weigelt; Jorge S Reis-Filho
Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas).
Journal of clinical pathology 2010;63(3):220-8.
2010: Nicholas Turner; Alex Pearson; Rachel Sharpe; Maryou Lambros; Felipe Geyer; Maria A Lopez-Garcia; Rachael Natrajan; Caterina Marchio; Elizabeth Jane Iorns; Alan Mackay; Cheryl Gillett; Anita Grigoriadis; Andrew Tutt; Jorge S Reis-Filho; Alan Ashworth
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.
Cancer research 2010;70(5):2085-94.
2010: Tarek M Abdel-Fatah; Des G Powe; Johnson Agboola; Martyna Adamowicz-Brice; Roger W Blamey; Maria A Lopez-Garcia; Andrew Green; Jorge S Reis-Filho; Ian O Ellis
The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers.
The Journal of pathology 2010;220(4):419-34.
2010: Peter T Simpson; Jorge S Reis-Filho; Sunil R Lakhani
Breast pathology: beyond morphology.
Seminars in diagnostic pathology 2010;27(1):91-6.
2010: Pamela Klingbeil; Rachael Natrajan; Gemma Everitt; Radost Vatcheva; Caterina Marchio; Jose Palacios; Horst Buerger; Jorge S Reis-Filho; Clare M Isacke
CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification.
Breast cancer research and treatment 2010;120(1):95-109.
2010: Lee Lancashire; D G Powe; Jorge S Reis-Filho; E Rakha; C Lemetre; B Weigelt; T M Abdel-Fatah; Andrew Green; R Mukta; R Blamey; E C Paish; R C Rees; Ian O Ellis; G R Ball
A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks.
Breast cancer research and treatment 2010;120(1):83-93.
2010: Sonja J Heidorn; Carla Milagre; Steven Whittaker; Arnaud Nourry; Ion Niculescu-Duvas; Nathalie Dhomen; Jahan Hussain; Jorge S Reis-Filho; Caroline J Springer; Catrin Pritchard; Richard Marais
Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
Cell 2010;140(2):209-21.
2010: Magali Lacroix-Triki; Maryou B K Lambros; Felipe C Geyer; Paula H Suarez; Jorge S Reis-Filho; Britta Weigelt
Absence of microsatellite instability in mucinous carcinomas of the breast.
International journal of clinical and experimental pathology 2010;4(1):22-31.
2010: Britta Weigelt; Jorge S Reis-Filho
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry.
Breast cancer research : BCR 2010;12 Suppl 4():S5.
2010: Emad A Rakha; Jorge S Reis-Filho; Frederick Baehner; David J Dabbs; Thomas Decker; Vincenzo Eusebi; Stephen B Fox; Shu Ichihara; Jocelyne Jacquemier; Sunil R Lakhani; José Palacios; Andrea L Richardson; Stuart J Schnitt; Fernando C Schmitt; Puay Hoon Tan; Gary M Tse; Sunil Badve; Ian O Ellis
Breast cancer prognostic classification in the molecular era: the role of histological grade.
Breast cancer research : BCR 2010;12(4):207.
2010: Peter A Hall; Jorge S Reis-Filho; Ian Pm Tomlinson; Richard Poulsom
An introduction to genes, genomes and disease.
The Journal of pathology 2010;220(2):109-13.
2010: Britta Weigelt; Frederick L Baehner; Jorge S Reis-Filho
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade.
The Journal of pathology 2010;220(2):263-80.
2010: Britta Weigelt; Felipe C Geyer; Rachael Natrajan; Maria A Lopez-Garcia; Amar S Ahmad; Kay Savage; Bas Kreike; Jorge S Reis-Filho
The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type.
The Journal of pathology 2010;220(1):45-57.
2010: Robin L Jones; Janine Salter; Roger A'Hern; Ashutosh Nerurkar; Marina Parton; Jorge S Reis-Filho; Ian E Smith; Mitchell Dowsett
Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer.
Breast cancer research and treatment 2010;119(2):315-23.
2009: Philip J Stephens; David J McBride; Meng-Lay Lin; Ignacio Varela; Erin D Pleasance; Jared T Simpson; Lucy A Stebbings; Catherine Leroy; Sarah Edkins; Laura J Mudie; Chris D Greenman; Mingming Jia; Calli Latimer; Jon W Teague; King Wai Lau; John Burton; Michael A Quail; Harold Swerdlow; Carol Churcher; Rachael Natrajan; Anieta M Sieuwerts; John Martens; Daniel P Silver; Anita Langerød; Hege E G Russnes; John A Foekens; Jorge S Reis-Filho; Laura van 't Veer; Andrea L Richardson; Anne-Lise Børresen-Dale; Peter J Campbell; P Andrew Futreal; Michael R Stratton
Complex landscapes of somatic rearrangement in human breast cancer genomes.
Nature 2009;462(7276):1005-10.
2009: Britta Weigelt; Jorge S Reis-Filho
Histological and molecular types of breast cancer: is there a unifying taxonomy?
Nature reviews. Clinical oncology 2009;6(12):718-30.
2009: Felipe C Geyer; Yael B Kushner; Maryou B K Lambros; Rachael Natrajan; Alan Mackay; Narinder Tamber; Kerry Fenwick; Dave Purnell; Alan Ashworth; Rosemary A Walker; Jorge S Reis-Filho
Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma.
Histopathology 2009;55(6):732-43.
2009: Leisl M Packer; Philip East; Jorge S Reis-Filho; Richard Marais
Identification of direct transcriptional targets of (V600E)BRAF/MEK signalling in melanoma.
Pigment cell & melanoma research 2009;22(6):785-98.
2009: Alan Mackay; Narinder Tamber; Kerry Fenwick; Marjan Iravani; Anita Grigoriadis; Tim Dexter; Christopher J Lord; Jorge S Reis-Filho; Alan Ashworth
A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines.
Breast cancer research and treatment 2009;118(3):481-98.
2009: Afshan McCarthy; christopher Lord; Kay Savage; Anita Grigoriadis; Darrin P Smith; Britta Weigelt; Jorge S Reis-Filho; Alan Ashworth
Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.
The Journal of pathology 2009;219(3):306-16.
2009: Britta Weigelt; Felipe C Geyer; Hugo M Horlings; Bas Kreike; Hans Halfwerk; Jorge S Reis-Filho
Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(11):1401-14.
2009: Felipe C Geyer; Maria A Lopez-Garcia; Maryou B K Lambros; Jorge S Reis-Filho
Genetic characterization of breast cancer and implications for clinical management.
Journal of cellular and molecular medicine 2009;13(10):4090-103.
2009: Dorine A Bax; Nathalie Gaspar; Suzanne E Little; Lynley Marshall; Lara Perryman; Marie Regairaz; Marta Viana-Pereira; Raisa Vuononvirta; Swee Y Sharp; Jorge S Reis-Filho; João N Stávale; Safa Al-Sarraj; Rui M Reis; Gilles Vassal; Andrew D J Pearson; Darren Hargrave; David W Ellison; Paul Workman; Chris Jones
EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(18):5753-61.
2009: Olga Martinho; Adhemar Longatto Filho; Maryou B K Lambros; Albino Martins; C Pinheiro; A Silva; Fernando Pardal; J Amorim; A Mackay; Fernanda Milanezi; N Tamber; K Fenwick; A Ashworth; Jorge S Reis-Filho; José M Lopes; Rui M Reis
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.
British journal of cancer 2009;101(6):973-82.
2009: Caterina Marchiò; Maryou B K Lambros; Patrizia Gugliotta; Ludovica Verdun Di Cantogno; Cristina Botta; Barbara Pasini; David S P Tan; Alan Mackay; Kerry Fenwick; Narinder Tamber; Gianni Bussolati; Alan Ashworth; Jorge S Reis-Filho; Anna Sapino
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis.
The Journal of pathology 2009;219(1):16-24.
2009: C Westbury; Jorge S Reis-Filho; Tim Dexter; Betania Mahler-Araujo; Kerry Fenwick; Marjan Iravani; Anita Grigoriadis; Suzanne Parry; David Robertson; Alan Mackay; Alan Ashworth; John R Yarnold; Clare M Isacke
Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ERalpha) in response to therapeutic radiation.
The Journal of pathology 2009;219(1):131-40.
2009: Britta Weigelt; Bas Kreike; Jorge S Reis-Filho
Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis.
Breast cancer research and treatment 2009;117(2):273-80.
2009: Felipe Correa Geyer; Jorge S Reis-Filho
Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?
International journal of surgical pathology 2009;17(4):285-302.
2009: Maryou B K Lambros; David S P Tan; Robin L Jones; Radost Vatcheva; Kay Savage; N Tamber; Kerry Fenwick; Alan Mackay; Alan Ashworth; Jorge S Reis-Filho
Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication.
Journal of clinical pathology 2009;62(7):604-12.
2009: Caterina Marchiò; Marjan Iravani; Rachael Natrajan; Maryou B K Lambros; Felipe C Geyer; Kay Savage; Suzanne Parry; Narinder Tamber; Kerry Fenwick; Alan Mackay; Fernando C Schmitt; Gianni Bussolati; Ian O Ellis; Alan Ashworth; Anna Sapino; Jorge S Reis-Filho
Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components.
The Journal of pathology 2009;218(3):301-15.
2009: Robin L Jones; Janine Salter; Roger A'Hern; Ash Nerurkar; Marina Parton; Jorge S Reis-Filho; Ian E Smith; Mitchell Dowsett
The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer.
Breast cancer research and treatment 2009;116(1):53-68.
2009: Emad Rakha; Jorge S Reis-Filho
Basal-like breast carcinoma: from expression profiling to routine practice.
Archives of pathology & laboratory medicine 2009;133(6):860-8.
2009: Rachael Natrajan; Maryou B K Lambros; Socorro María Rodríguez-Pinilla; Gema Moreno-Bueno; David S P Tan; Caterina Marchió; Radost Vatcheva; Sydonia Rayter; Betania Mahler-Araujo; Laura G Fulford; Daniela Hungermann; Alan Mackay; Anita Grigoriadis; Kerry Fenwick; Narinder Tamber; David Hardisson; Andrew Tutt; José Palacios; christopher Lord; Horst Buerger; Alan Ashworth; Jorge S Reis-Filho
Tiling path genomic profiling of grade 3 invasive ductal breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2711-22.
2009: Raisa Vuononvirta; Neil J Sebire; Boo Messahel; Nina Perusinghe; Jorge S Reis-Filho; Kathy Pritchard-Jones; Gordan M Vujanic; Chris Jones
Expression of hepatocyte growth factor and its receptor met in Wilms' tumors and nephrogenic rests reflects their roles in kidney development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2723-30.
2009: Nathalie Dhomen; Jorge S Reis-Filho; Silvy da Rocha Dias; Robert Hayward; Kay Savage; Veronique Delmas; Lionel Larue; Catrin Pritchard; Richard Marais
Oncogenic Braf induces melanocyte senescence and melanoma in mice.
Cancer cell 2009;15(4):294-303.
2009: Emad A Rakha; Somaia E Elsheikh; Mohammed Aleskandarany; Hany O Habashi; Andrew Green; Desmond G Powe; Maysa E El-Sayed; Ahmed Benhasouna; Jean-Sebastien Brunet; Lars A Akslen; Andy J Evans; Roger Blamey; Jorge S Reis-Filho; William D Foulkes; Ian O Ellis
Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(7):2302-10.
2009: David S P Tan; Maryou B K Lambros; Sydonia Rayter; Rachael Natrajan; Radost Vatcheva; Qiong Gao; Caterina Marchiò; Felipe C Geyer; Kay Savage; Suzanne Parry; Kerry Fenwick; Narinder Tamber; Alan Mackay; Tim Dexter; Charles Jameson; W Glenn McCluggage; Alistair R W Williams; Ashley Graham; Dana Faratian; Mona El-Bahrawy; Adam J Paige; Hani Gabra; Martin E Gore; Marketa Zvelebil; Christopher J Lord; Stanley B Kaye; Alan Ashworth; Jorge S Reis-Filho
PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(7):2269-80.
2009: Rachael Natrajan; Maryou B K Lambros; Felipe C Geyer; Caterina Marchio; David S P Tan; Radost Vatcheva; Kai-Keen Shiu; Daniela Hungermann; Socorro Maria Rodriguez-Pinilla; José Palacios; Alan Ashworth; Horst Buerger; Jorge S Reis-Filho
Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype?
Genes, chromosomes & cancer 2009;48(4):351-65.
2009: Rafael Malagoli Rocha; Cristiana Buzelin Nunes; Fernanda Squarcio Fernandes Sanches; Gislene Fátima Silva Rocha; Flávio Nepomuceno de Oliveira; Jorge S Reis-Filho; Maryou B Lambros; Helenice Gobbi
Rabbit antibodies for hormone receptors and HER2 evaluation in breast cancer.
Revista da Associação Médica Brasileira (1992) 2009;55(2):163-8.
2009: F C Geyer; T Decker; Jorge S Reis-Filho
[Genome-wide expression profiling as a clinical tool: are we there yet?].
Der Pathologe 2009;30(2):141-6.
2009: Emad A Rakha; Maysa E El-Sayed; Jorge S Reis-Filho; Ian O Ellis
Patho-biological aspects of basal-like breast cancer.
Breast cancer research and treatment 2009;113(3):411-22.
2009: Jorge S Reis-Filho
Next-generation sequencing.
Breast cancer research : BCR 2009;11 Suppl 3():S12.
2009: Elizabeth Jane Iorns; Christopher J Lord; Anita Grigoriadis; Sarah McDonald; Kerry Fenwick; Alan Mackay; Charles A Mein; Rachael Natrajan; Kay Savage; Narinder Tamber; Jorge S Reis-Filho; Nicholas C Turner; Alan Ashworth
Integrated functional, gene expression and genomic analysis for the identification of cancer targets.
PloS one 2009;4(4):e5120.
2009: Felipe C Geyer; Caterina Marchio; Jorge S Reis-Filho
The role of molecular analysis in breast cancer.
Pathology 2009;41(1):77-88.
2008: Raisa Vuononvirta; Neil J Sebire; Anthony R Dallosso; Jorge S Reis-Filho; Richard D Williams; Alan Mackay; Kerry Fenwick; Anita Grigoriadis; Alan Ashworth; Kathy Pritchard-Jones; Keith W Brown; Gordan M Vujanic; Chris Jones
Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-II-associated Wilms tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(23):7635-44.
2008: C Marchiò; Rachael Natrajan; K K Shiu; Maryou B K Lambros; S M Rodriguez-Pinilla; D S P Tan; christopher Lord; D Hungermann; Kerry Fenwick; N Tamber; Alan Mackay; José Palacios; A Sapino; H Buerger; Alan Ashworth; Jorge S Reis-Filho
The genomic profile of HER2-amplified breast cancers: the influence of ER status.
The Journal of pathology 2008;216(4):399-407.
2008: Jorge S Reis-Filho; Sunil R Lakhani
Breast cancer special types: why bother?
The Journal of pathology 2008;216(4):394-8.
2008: D S P Tan; Maryou B K Lambros; C Marchiò; Jorge S Reis-Filho
ESR1 amplification in endometrial carcinomas: hope or hyperbole?
The Journal of pathology 2008;216(3):271-4.
2008: D S P Tan; C Marchiò; Jorge S Reis-Filho
Hereditary breast cancer: from molecular pathology to tailored therapies.
Journal of clinical pathology 2008;61(10):1073-82.
2008: Kai-Keen Shiu; David S P Tan; Jorge S Reis-Filho
Development of therapeutic approaches to 'triple negative' phenotype breast cancer.
Expert opinion on therapeutic targets 2008;12(9):1123-37.
2008: S Parry; K Savage; C Marchiò; Jorge S Reis-Filho
Nestin is expressed in basal-like and triple negative breast cancers.
Journal of clinical pathology 2008;61(9):1045-50.
2008: David S P Tan; Caterina Marchió; Robin L Jones; Kay Savage; Ian E Smith; Mitch Dowsett; Jorge S Reis-Filho
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients.
Breast cancer research and treatment 2008;111(1):27-44.
2008: Emad A Rakha; Ian O Ellis; Jorge S Reis-Filho
Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(8):1060-1; author reply 1061-2.
2008: C Marchiò; Marjan Iravani; Rachael Natrajan; M B Lambros; Kay Savage; N Tamber; Kerry Fenwick; Alan Mackay; R Senetta; S Di Palma; F C Schmitt; G Bussolati; L O Ellis; Alan Ashworth; A Sapino; Jorge S Reis-Filho
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast.
The Journal of pathology 2008;215(4):398-410.
2008: C B Nunes; R M Rocha; Jorge S Reis-Filho; M B Lambros; G F S Rocha; F S F Sanches; F N Oliveira; Helenice Gobbi
Comparative analysis of six different antibodies against Her2 including the novel rabbit monoclonal antibody (SP3) and chromogenic in situ hybridisation in breast carcinomas.
Journal of clinical pathology 2008;61(8):934-8.
2008: S E Elsheikh; Andrew Green; E A Rakha; R M Samaka; A A Ammar; D Powe; Jorge S Reis-Filho; Ian O Ellis
Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype.
British journal of cancer 2008;99(2):327-34.
2008: Jorge S Reis-Filho; Suzanne Drury; Maryou B Lambros; Caterina Marchio; Nichola Johnson; Rachael Natrajan; Janine Salter; Pauline Levey; Olivia Fletcher; Julian Peto; Alan Ashworth; Mitch Dowsett
ESR1 gene amplification in breast cancer: a common phenomenon?
Nature genetics 2008;40(7):809-10; author reply 810-2.
2008: Peter T Simpson; Jorge S Reis-Filho; M B K Lambros; C Jones; D Steele; Alan Mackay; M Iravani; K Fenwick; Tim Dexter; A Jones; L Reid; L Da Silva; S J Shin; D Hardisson; Alan Ashworth; Fernando C Schmitt; José Palacios; Sunil R Lakhani
Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas.
The Journal of pathology 2008;215(3):231-44.
2008: Kay Savage; Samuel Leung; S Katrina Todd; Lindsay A Brown; Robin L Jones; David Robertson; Michelle James; Suzanne Parry; S Maria Rodrigues Pinilla; David Huntsman; Jorge S Reis-Filho
Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis.
Breast cancer research and treatment 2008;110(2):245-56.
2008: Jorge S Reis-Filho; Rachael Natrajan; R Vatcheva; M B K Lambros; C Marchió; B Mahler-Araújo; C Paish; Z Hodi; V Eusebi; Ian O Ellis
Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6'split apart' probes.
Histopathology 2008;52(7):840-6.
2008: Emad A Rakha; Jorge S Reis-Filho; Ian O Ellis
Basal-like breast cancer: a critical review.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(15):2568-81.
2008: Edurne Arriola; Caterina Marchio; David S P Tan; Suzanne C Drury; Maryou B K Lambros; Rachael Natrajan; Socorro Maria Rodriguez-Pinilla; Alan Mackay; Narinder Tamber; Kerry Fenwick; Chris Jones; Mitch Dowsett; Alan Ashworth; Jorge S Reis-Filho
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines.
Laboratory investigation; a journal of technical methods and pathology 2008;88(5):491-503.
2008: B Mahler-Araujo; K Savage; S Parry; Jorge S Reis-Filho
Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype.
Journal of clinical pathology 2008;61(5):615-20.
2008: Somaia Elsheikh; Andrew Green; Mohammed Aleskandarany; Matthew Grainge; Claire E Paish; Maryou B K Lambros; Jorge S Reis-Filho; Ian O Ellis
CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome.
Breast cancer research and treatment 2008;109(2):325-35.
2008: Matthew J Smalley; Jorge S Reis-Filho; Alan Ashworth
BRCA1 and stem cells: tumour typecasting.
Nature cell biology 2008;10(4):377-9.
2008: Tarek M A Abdel-Fatah; Desmond G Powe; Zsolt Hodi; Jorge S Reis-Filho; Andrew H S Lee; Ian O Ellis
Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family.
The American journal of surgical pathology 2008;32(4):513-23.
2008: Mangesh Thorat; C Marchio; Akira Morimiya; K Savage; Harikrishna Nakshatri; Jorge S Reis-Filho; Sunil Badve
Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis.
Journal of clinical pathology 2008;61(3):327-32.
2008: Stacey L Edwards; Rachel Brough; christopher Lord; Rachael Natrajan; Radost Vatcheva; Douglas A Levine; Jeff Boyd; Jorge S Reis-Filho; Alan Ashworth
Resistance to therapy caused by intragenic deletion in BRCA2.
Nature 2008;451(7182):1111-5.
2008: Emad A Rakha; Jorge S Reis-Filho; Ian O Ellis
Impact of basal-like breast carcinoma determination for a more specific therapy.
Pathobiology : journal of immunopathology, molecular and cellular biology 2008;75(2):95-103.
2008: David S P Tan; Jorge S Reis-Filho
Comparative genomic hybridisation arrays: high-throughput tools to determine targeted therapy in breast cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology 2008;75(2):63-74.
2008: David Robertson; Kay Savage; Jorge S Reis-Filho; Clare M Isacke
Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue.
BMC cell biology 2008;9():13.
2008: Jorge S Reis-Filho; Andrew Tutt
Triple negative tumours: a critical review.
Histopathology 2008;52(1):108-18.
2008: Emad A Rakha; Maysa E El-Sayed; Jorge S Reis-Filho; Ian O Ellis
Expression profiling technology: its contribution to our understanding of breast cancer.
Histopathology 2008;52(1):67-81.
2008: Rachael Natrajan; W Warren; Boo Messahel; Jorge S Reis-Filho; Marie-Anne Brundler; Jeffrey S Dome; Paul E Grundy; Gordan M Vujanic; Kathy Pritchard-Jones; Chris Jones
Complex patterns of chromosome 9 alterations including the p16INK4a locus in Wilms tumours.
Journal of clinical pathology 2008;61(1):95-102.
2007: Selma Esseghir; S Katrina Todd; Toby Hunt; Richard Poulsom; Ivan Plaza-Menacho; Jorge S Reis-Filho; Clare M Isacke
A role for glial cell derived neurotrophic factor induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer.
Cancer research 2007;67(24):11732-41.
2007: Sarah Elizabeth Pinder; Jorge S Reis-Filho
Non-operative breast pathology.
Journal of clinical pathology 2007;60(12):1297-9.
2007: Andrew H S Lee; E C Paish; C Marchio; A Sapino; F C Schmitt; Ian O Ellis; Jorge S Reis-Filho
The expression of Wilms' tumour-1 and Ca125 in invasive micropapillary carcinoma of the breast.
Histopathology 2007;51(6):824-8.
2007: Edurne Arriola; Socorro Maria Rodriguez-Pinilla; Maryou B K Lambros; Robin L Jones; Michelle James; Kay Savage; Ian E Smith; Mitch Dowsett; Jorge S Reis-Filho
Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer.
Breast cancer research and treatment 2007;106(2):181-9.
2007: Jorge S Reis-Filho; Sarah Elizabeth Pinder
Non-operative breast pathology: lobular neoplasia.
Journal of clinical pathology 2007;60(12):1321-7.
2007: Sarah Elizabeth Pinder; Jorge S Reis-Filho
Non-operative breast pathology: columnar cell lesions.
Journal of clinical pathology 2007;60(12):1307-12.
2007: Dirk Wienke; Gareth C Davies; Damian A Johnson; Justin Sturge; Maryou B K Lambros; Kay Savage; Somaia Elbauomy Elsheikh; Andrew Green; Ian O Ellis; David Robertson; Jorge S Reis-Filho; Clare M Isacke
The collagen receptor Endo180 (CD280) Is expressed on basal-like breast tumor cells and promotes tumor growth in vivo.
Cancer research 2007;67(21):10230-40.
2007: Chris Jones; Maria Rodriguez-Pinilla; Maryou B K Lambros; Dorine A Bax; Boo Messahel; Gordan M Vujanic; Jorge S Reis-Filho; Kathy Pritchard-Jones
c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours.
Journal of clinical pathology 2007;60(11):1226-31.
2007: Charlotte Westbury; A Pearson; A Nerurkar; Jorge S Reis-Filho; D Steele; Clare Peckitt; G Sharp; John Yarnold
Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride.
The British journal of radiology 2007;80(959):934-8.
2007: S Maria Rodriguez-Pinilla; Robin L Jones; Maryou B K Lambros; Edurne Arriola; Kay Savage; Michelle James; Sarah Elizabeth Pinder; Jorge S Reis-Filho
MYC amplification in breast cancer: a chromogenic in situ hybridisation study.
Journal of clinical pathology 2007;60(9):1017-23.
2007: Suzanne E Little; Dorine A Bax; Maria Rodriguez-Pinilla; Rachael Natrajan; Boo Messahel; Kathy Pritchard-Jones; Gordan M Vujanic; Jorge S Reis-Filho; Chris Jones
Multifaceted dysregulation of the epidermal growth factor receptor pathway in clear cell sarcoma of the kidney.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(15 Pt 1):4360-4.
2007: Maryou B K Lambros; Rachael Natrajan; Jorge S Reis-Filho
Chromogenic and fluorescent in situ hybridization in breast cancer.
Human pathology 2007;38(8):1105-22.
2007: David S P Tan; Maryou B K Lambros; Rachael Natrajan; Jorge S Reis-Filho
Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research.
Laboratory investigation; a journal of technical methods and pathology 2007;87(8):737-54.
2007: Selma Esseghir; Alan Kennedy; Pooja Seedhar; Ashutosh Nerurkar; Richard Poulsom; Jorge S Reis-Filho; Clare M Isacke
Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(11):3164-73.
2007: Silvana Di Palma; Maryou B K Lambros; Kay Savage; Chris Jones; Alan Mackay; Tim Dexter; Marjan Iravani; Kerry Fenwick; Alan Ashworth; Jorge S Reis-Filho
Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells.
Journal of clinical pathology 2007;60(5):492-9.
2007: Marc Tischkowitz; Bing Xia; Nelly Sabbaghian; Jorge S Reis-Filho; Nancy Hamel; Guilan Li; erik van beers; Lili Li; Tayma Khalil; Louise A Quenneville; Atilla Omeroglu; Aletta Poll; Pierre Lepage; Nora Wong; petra nederlof; Alan Ashworth; Patricia N Tonin; Steven A Narod; David M Livingston; William D Foulkes
Analysis of PALB2/FANCN-associated breast cancer families.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6788-93.
2007: Sarah Elizabeth Pinder; Elena Provenzano; Jorge S Reis-Filho
Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management.
Pathology 2007;39(2):208-16.
2007: Socorro M Rodriguez-Pinilla; David Sarrio; Gema Moreno-Bueno; Yolanda Rodriguez-Gil; Miguel A Martinez; Lucia Hernandez; David Hardisson; Jorge S Reis-Filho; José Palacios
Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(4):474-81.
2007: Maria Fernanda C Amary; Fitim Berisha; Fabiola Del Carlo Bernardi; Amanda Herbert; Michelle James; Jorge S Reis-Filho; Cyril Fisher; Andrew G Nicholson; Roberto Tirabosco; Tim C Diss; Adrienne M Flanagan
Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(4):482-96.
2007: Nicholas C Turner; Jorge S Reis-Filho; A M Russell; Robert J Springall; Kenneth Ryder; Dawn Steele; Kay Savage; Cheryl E Gillett; Fernando C Schmitt; Alan Ashworth; Andrew Tutt
BRCA1 dysfunction in sporadic basal-like breast cancer.
Oncogene 2007;26(14):2126-32.
2007: Tarek M A Abdel-Fatah; Desmond G Powe; Zsolt Hodi; Andrew H S Lee; Jorge S Reis-Filho; Ian O Ellis
High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma.
The American journal of surgical pathology 2007;31(3):417-26.
2007: A McCarthy; Kay Savage; A Gabriel; C Naceur; Jorge S Reis-Filho; Alan Ashworth
A mouse model of basal-like breast carcinoma with metaplastic elements.
The Journal of pathology 2007;211(4):389-98.
2007: Paraskevi Briassouli; Florence Chan; Kay Savage; Jorge S Reis-Filho; Spiros Linardopoulos
Aurora-A regulation of nuclear factor-kappaB signaling by phosphorylation of IkappaBalpha.
Cancer research 2007;67(4):1689-95.
2007: J-Y Pierga; Jorge S Reis-Filho; Susan J Cleator; Tim Dexter; Alan Mackay; P Simpson; Kerry Fenwick; Marjan Iravani; Janine Salter; Margaret Hills; Chris Jones; Alan Ashworth; Ian E Smith; T Powles; Mitch Dowsett
Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy.
British journal of cancer 2007;96(2):341-51.
2007: Emad A Rakha; David S P Tan; William D Foulkes; Ian O Ellis; Andrew Tutt; Torsten O Nielsen; Jorge S Reis-Filho
Are triple-negative tumours and basal-like breast cancer synonymous?
Breast cancer research : BCR 2007;9(6):404; author reply 405.
2007: Ana L Gomes; Jorge S Reis-Filho; José M Lopes; Olga Martinho; Maryou B K Lambros; Albino Martins; Fernando Schmitt; Fernando Pardal; Rui M Reis
Molecular alterations of KIT oncogene in gliomas.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(5):399-408.
2007: Somaia Elbauomy Elsheikh; Andrew Green; Maryou B K Lambros; Nicholas C Turner; Matthew J Grainge; Desmond G Powe; Ian O Ellis; Jorge S Reis-Filho
FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis.
Breast cancer research : BCR 2007;9(2):R23.
2007: Laura G Fulford; Jorge S Reis-Filho; Kenneth Ryder; Chris Jones; Cheryl E Gillett; Andrew M Hanby; Douglas Easton; Sunil R Lakhani
Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival.
Breast cancer research : BCR 2007;9(1):R4.
2007: Kay Savage; Maryou B K Lambros; David Robertson; Robin L Jones; Chris Jones; Alan Mackay; Michelle James; Jason L Hornick; Emílio M Pereira; Fernanda Milanezi; Christopher D M Fletcher; Fernando C Schmitt; Alan Ashworth; Jorge S Reis-Filho
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):90-101.
2007: Edurne Arriola; Maryou B K Lambros; Chris Jones; Tim Dexter; Alan Mackay; David S P Tan; Narinder Tamber; Kerry Fenwick; Alan Ashworth; Mitch Dowsett; Jorge S Reis-Filho
Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation.
Laboratory investigation; a journal of technical methods and pathology 2007;87(1):75-83.
2007: Rachael Natrajan; Suzanne E Little; N Sodha; Jorge S Reis-Filho; Alan Mackay; Kerry Fenwick; Alan Ashworth; Elizabeth J. Perlman; Jeffrey S Dome; Paul E Grundy; Kathy Pritchard-Jones; Chris Jones
Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour.
The Journal of pathology 2007;211(1):52-9.
2006: Rachael Natrajan; Suzanne E Little; Jorge S Reis-Filho; Lara Hing; Boo Messahel; Paul E Grundy; Jeffrey S Dome; Toni Schneider; Gordan M Vujanic; Kathy Pritchard-Jones; Chris Jones
Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7284-93.
2006: Rachael Natrajan; Jorge S Reis-Filho; Suzanne E Little; Boo Messahel; Marie-Anne Brundler; Jeffrey S Dome; Paul E Grundy; Gordan M Vujanic; Kathy Pritchard-Jones; Chris Jones
Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.
Cancer research 2006;66(23):11148-55.
2006: Selma Esseghir; Jorge S Reis-Filho; A Kennedy; M James; M J O'Hare; R Jeffery; Richard Poulsom; Clare M Isacke
Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts.
The Journal of pathology 2006;210(4):420-30.
2006: Jorge S Reis-Filho; Peter T Simpson; Nicholas C Turner; Maryou B K Lambros; Chris Jones; Alan Mackay; Anita Grigoriadis; David Sarrio; Kay Savage; Tim Dexter; Marjan Iravani; Kerry Fenwick; Barbara Weber; David Hardisson; Fernando C Schmitt; José Palacios; Sunil R Lakhani; Alan Ashworth
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6652-62.
2006: Nicholas C Turner; Jorge S Reis-Filho
Basal-like breast cancer and the BRCA1 phenotype.
Oncogene 2006;25(43):5846-53.
2006: Rachael Natrajan; Richard D Williams; Sandra Hing; Alan Mackay; Jorge S Reis-Filho; Kerry Fenwick; Marjan Iravani; Haukur Valgeirsson; Anita Grigoriadis; Cordelia F Langford; Oliver M Dovey; Simon G Gregory; B L Weber; Alan Ashworth; Paul E Grundy; Kathy Pritchard-Jones; Chris Jones
Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.
The Journal of pathology 2006;210(1):49-58.
2006: Jorge S Reis-Filho; Céline Pinheiro; Maryou B K Lambros; Fernanda Milanezi; Silvia Carvalho; Kay Savage; Peter T Simpson; Chris Jones; S Swift; Alan Mackay; Rui M Reis; J L Hornick; Emílio M Pereira; Fátima Baltazar; Christopher D M Fletcher; Alan Ashworth; Sunil R Lakhani; Fernando C Schmitt
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas.
The Journal of pathology 2006;209(4):445-53.
2006: Laura G Fulford; D F Easton; Jorge S Reis-Filho; A Sofronis; Cheryl E Gillett; Sunil R Lakhani; Andrew M Hanby
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast.
Histopathology 2006;49(1):22-34.
2006: Jorge S Reis-Filho; Fernanda Milanezi; Dawn Steele; Kay Savage; Peter T Simpson; Jahn M Nesland; Emílio M Pereira; Sunil R Lakhani; Fernando C Schmitt
Metaplastic breast carcinomas are basal-like tumours.
Histopathology 2006;49(1):10-21.
2006: Jorge S Reis-Filho; Kay Savage; Maryou B K Lambros; Michelle James; Dawn Steele; Robin L Jones; Mitch Dowsett
Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(7):999-1009.
2006: S Banerjee; Jorge S Reis-Filho; S Ashley; D Steele; Alan Ashworth; S R Lakhani; I E Smith
Basal-like breast carcinomas: clinical outcome and response to chemotherapy.
Journal of clinical pathology 2006;59(7):729-35.
2006: Maryou B K Lambros; Peter T Simpson; Chris Jones; Rachael Natrajan; Charlotte Westbury; Dawn Steele; Kay Savage; Alan Mackay; Fernando C Schmitt; Alan Ashworth; Jorge S Reis-Filho
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization.
Laboratory investigation; a journal of technical methods and pathology 2006;86(4):398-408.
2006: Jorge S Reis-Filho; Charlotte Westbury; J-Y Pierga
The impact of expression profiling on prognostic and predictive testing in breast cancer.
Journal of clinical pathology 2006;59(3):225-31.
2006: Jorge S Reis-Filho; Dawn Steele; Silvana Di Palma; Robin L Jones; Kay Savage; Michelle James; Fernanda Milanezi; Fernando C Schmitt; Alan Ashworth
Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(2):307-19.
2006: Suzanne E Little; Raisa Vuononvirta; Jorge S Reis-Filho; Rachael Natrajan; Marjan Iravani; Kerry Fenwick; Alan Mackay; Alan Ashworth; Kathy Pritchard-Jones; Chris Jones
Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.
Genomics 2006;87(2):298-306.
2006: Anita Grigoriadis; Alan Mackay; Jorge S Reis-Filho; Dawn Steele; Christian Iseli; Brian J Stevenson; Victor Jongeneel; Haukur Valgeirsson; Kerry Fenwick; Marjan Iravani; Maria Leao; Andrew J G Simpson; Robert L Strausberg; Parmjit S Jat; Alan Ashworth; A Munro Neville; Michael J O'Hare
Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.
Breast cancer research : BCR 2006;8(5):R56.
2005: Jorge S Reis-Filho; Fernando Carlos de Landér Schmitt
Fluorescence in situ hybridization, comparative genomic hybridization, and other molecular biology techniques in the analysis of effusions.
Diagnostic cytopathology 2005;33(5):294-9.
2005: Jorge S Reis-Filho
Re: Korsching et al. The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol 2005; 206: 451-457.
The Journal of pathology 2005;207(3):367-9; author reply 370-1.
2005: Jean-Yves Pierga; Jorge S Reis-Filho
Ewing's sarcoma of the rectum: can we afford not to use molecular pathology?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7761-2; author reply 7762.
2005: Jorge S Reis-Filho; Peter T Simpson; Chris Jones; Dawn Steele; Alan Mackay; Marjan Iravani; Kerry Fenwick; Haukur Valgeirsson; Maryou B K Lambros; Alan Ashworth; José Palacios; Fernando Schmitt; Sunil R Lakhani
Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity.
The Journal of pathology 2005;207(1):1-13.
2005: Sunil R Lakhani; Jorge S Reis-Filho; Laura Fulford; Frederique Penault-Llorca; Marc van der Vijver; Suzanne Parry; Timothy Bishop; Javier Benitez; Carmen Rivas; Yves-Jean Bignon; Jenny Chang-Claude; Ute Hamann; Cees J Cornelisse; Peter Devilee; Matthias W Beckmann; Carolin Nestle-Krämling; Peter A Daly; Neva Haites; Jenny Varley; Fiona Lalloo; Gareth Evans; Christine Maugard; Hanne Meijers-Heijboer; Jan G M Klijn; Edith Olah; barry gusterson; Silvana Pilotti; Paolo Radice; Siegfried Scherneck; Hagay Sobol; Jocelyne Jacquemier; Teresa Wagner; Julian Peto; Michael R Stratton; Lesley McGuffog; Douglas F Easton
Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5175-80.
2005: Peter T Simpson; Theodora Gale; Jorge S Reis-Filho; Chris Jones; Suzanne Parry; John P Sloane; Andrew M Hanby; Sarah Elizabeth Pinder; Andrew H S Lee; stephen humphreys; Ian O Ellis; Sunil R Lakhani
Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis.
The American journal of surgical pathology 2005;29(6):734-46.
2005: Jorge S Reis-Filho; Peter T Simpson; Theodora Gale; Sunil R Lakhani
The molecular genetics of breast cancer: the contribution of comparative genomic hybridization.
Pathology, research and practice 2005;201(11):713-25.
2005: Rui M Reis; Jorge S Reis-Filho; Adhemar Longatto Filho; Stanislav I Tomarev; Paula Silva; José M Lopes
Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors.
Pathology, research and practice 2005;201(12):771-6.
2005: Jorge S Reis-Filho; Fernanda Milanezi; Silvia Carvalho; Peter T Simpson; Dawn Steele; Kay Savage; Maryou B K Lambros; Emílio M Pereira; Jahn M Nesland; Sunil R Lakhani; Fernando C Schmitt
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis.
Breast cancer research : BCR 2005;7(6):R1028-35.
2005: Peter T Simpson; Jorge S Reis-Filho; Theodora Gale; Sunil R Lakhani
Molecular evolution of breast cancer.
The Journal of pathology 2005;205(2):248-54.
2004: Sandra Angèle; Chris Jones; Jorge S Reis-Filho; Laura G Fulford; Isabelle Treilleux; Sunil R Lakhani; Janet Hall
Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast.
Journal of clinical pathology 2004;57(11):1179-84.
2004: Catherine L Clarke; Jennifer Sandle; Suzanne C Parry; Jorge S Reis-Filho; Michael J O'Hare; Sunil R Lakhani
Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype.
The Journal of pathology 2004;204(2):147-52.
2004: Chris Jones; Emily Ford; Cheryl E Gillett; Kenneth Ryder; Samantha Merrett; Jorge S Reis-Filho; Laura G Fulford; Andrew M Hanby; Sunil R Lakhani
Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 1):5988-97.
2004: Ana Preto; José Cameselle-Teijeiro; Julio Moldes-Boullosa; Paula Soares; Jorge F Cameselle-Teijeiro; Paula Silva; Jorge S Reis-Filho; Rosa M Reyes-Santías; Natividad Alfonsín-Barreiro; Jerónimo Forteza; Manuel Sobrinho-Simões
Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(7):819-26.
2004: Chris Jones; Alan Mackay; Anita Grigoriadis; Antonio Cossu; Jorge S Reis-Filho; Laura G Fulford; Tim Dexter; Susan Davies; Karen Bulmer; Emily Ford; Suzanne Parry; Mario Budroni; Giuseppe Palmieri; A Munro Neville; Michael J O'Hare; Sunil R Lakhani
Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer.
Cancer research 2004;64(9):3037-45.
2004: Peter T Simpson; Theodora Gale; Jorge S Reis-Filho; Chris Jones; Suzanne Parry; Dawn Steele; Antonio Cossu; Mario Budroni; Giuseppe Palmieri; Sunil R Lakhani
Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue.
The Journal of pathology 2004;202(3):274-85.
2004: Jorge S Reis-Filho; Sara Ricardo; Fátima Gärtner; Fernando C Schmitt
Bilateral gonadoblastomas in a dog with mixed gonadal dysgenesis.
Journal of comparative pathology 2004;130(2-3):229-33.
2004: J Cruz; Jorge S Reis-Filho; J M Lopes
Malignant peripheral nerve sheath tumour-like primary cutaneous malignant melanoma.
Journal of clinical pathology 2004;57(2):218-20.
2004: Jorge S Reis-Filho; Maria Emília Paiva; José Manuel Lopes
August 2003: 47-year-old female with a 7-year history of osteomalacia and hypophosphatemia.
Brain pathology (Zurich, Switzerland) 2004;14(1):111-2, 115.
2004: Jorge S Reis-Filho; Laura G Fulford; B Crebassa; S Carpentier; Sunil R Lakhani
Collagenous spherulosis in an adenomyoepithelioma of the breast.
Journal of clinical pathology 2004;57(1):83-6.
2003: Jorge S Reis-Filho; Laura G Fulford; Alex Freeman; Sunil R Lakhani
Pathologic quiz case: a 93-year-old woman with an enlarged and tender left breast. Histiocytoid variant of lobular breast carcinoma.
Archives of pathology & laboratory medicine 2003;127(12):1626-8.
2003: Jorge S Reis-Filho; Laura G Fulford; Sunil R Lakhani; Fernando C Schmitt
Pathologic quiz case: a 62-year-old woman with a 4.5-cm nodule in the right breast. Lipid-rich breast carcinoma.
Archives of pathology & laboratory medicine 2003;127(9):e396-8.
2003: Jorge S Reis-Filho; C Gonçalves; Fátima Gärtner
Rectal leiomyosarcoma in a dog and review of gastrointestinal stromal tumours.
The Veterinary record 2003;153(7):215-7.
2003: Jorge S Reis-Filho; Peter T Simpson; Albino Martins; Ana Preto; Fátima Gärtner; Fernando C Schmitt
Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray.
Virchows Archiv : an international journal of pathology 2003;443(2):122-32.
2003: M Pia-Foschini; Jorge S Reis-Filho; Vincenzo Eusebi; S R Lakhani
Salivary gland-like tumours of the breast: surgical and molecular pathology.
Journal of clinical pathology 2003;56(7):497-506.
2003: Jorge S Reis-Filho; Fernanda Milanezi; Isabel Amendoeira; André Albergaria; Fernando C Schmitt
Distribution of p63, a novel myoepithelial marker, in fine-needle aspiration biopsies of the breast: an analysis of 82 samples.
Cancer 2003;99(3):172-9.
2003: Jorge S Reis-Filho
Re: Sastre-Garau et al. Inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: clinicopathological and genetic analysis of a case with evidence for clonality. J Pathol 2002; 196: 97-102.
The Journal of pathology 2003;200(2):269-71; author reply 271.
2003: Jorge S Reis-Filho; José Manuel Lopes
Pathologic quiz case: a 53-year-old man with a slowly enlarging mass in the right leg.
Archives of pathology & laboratory medicine 2003;127(5):627-8.
2003: João Cruz; Jorge S Reis-Filho; José Manuel Lopes
Primary cutaneous malignant melanoma with lipoblast-like cells.
Archives of pathology & laboratory medicine 2003;127(3):370-1.
2003: Jorge S Reis-Filho
Primary salivary clear cell tumors.
Archives of pathology & laboratory medicine 2003;127(3):278-9; author reply 279.
2003: Jorge S Reis-Filho; Fernanda Milanezi; Joana Paredes; Paula Silva; Emílio M Pereira; Sueli A Maeda; Leda V de Carvalho; Fernando C Schmitt
Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2003;11(1):1-8.
2003: Jorge S Reis-Filho; Fernando C Schmitt
Lymphangiogenesis in tumors: what do we know?
Microscopy research and technique 2003;60(2):171-80.
2003: Jorge S Reis-Filho; Peter T Simpson; Laura G Fulford; Albino Martins; Fernando C Schmitt
P63-driven nuclear accumulation of beta-catenin is not a frequent event in human neoplasms.
Pathology, research and practice 2003;199(12):785-93.
2003: Jorge S Reis-Filho; Sunil R Lakhani
The diagnosis and management of pre-invasive breast disease: genetic alterations in pre-invasive lesions.
Breast cancer research : BCR 2003;5(6):313-9.
2003: Peter T Simpson; Theodora Gale; Laura G Fulford; Jorge S Reis-Filho; Sunil R Lakhani
The diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ.
Breast cancer research : BCR 2003;5(5):258-62.
2003: João Cruz; Jorge S Reis-Filho; Paula Silva; José Manuel Lopes
Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas.
Oncology 2003;65(1):72-82.
2003: Fernando C Schmitt; Jorge S Reis-Filho
c-myc, not her-2/neu, can predict the prognosis of breast cancer patients: how novel, how accurate, and how significant?
Breast cancer research : BCR 2003;5(4):188-91.
2003: João Cruz; Jorge S Reis-Filho; José Manuel Lopes
Cutaneous malignant melanoma: the great simulator.
International journal of surgical pathology 2003;11(1):35.
2003: Jorge S Reis-Filho; Ana Preto; Paula Soares; Sara Ricardo; José Cameselle-Teijeiro; Manuel Sobrinho-Simões
p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(1):43-8.
2003: Jorge S Reis-Filho; F C Schmitt
p63 expression in sarcomatoid/metaplastic carcinomas of the breast.
Histopathology 2003;42(1):94-5.
2002: Fernando C Schmitt; Jorge S Reis-Filho
Oncogenes, granules and breast cancer: what has c-myc to do with apocrine changes?
Breast (Edinburgh, Scotland) 2002;11(6):463-5.
2002: Jorge S Reis-Filho; Beatriz Torio; André Albergaria; Fernando C Schmitt
Maspin expression in normal skin and usual cutaneous carcinomas.
Virchows Archiv : an international journal of pathology 2002;441(6):551-8.
2002: Jorge S Reis-Filho; Fernanda Milanezi; Isabel Amendoeira; André Albergaria; Fernando C Schmitt
p63 Staining of myoepithelial cells in breast fine needle aspirates: a study of its role in differentiating in situ from invasive ductal carcinomas of the breast.
Journal of clinical pathology 2002;55(12):936-9.
2002: Jorge S Reis-Filho; Maria Emília Paiva; José Manuel Lopes
Pathologic quiz case. A 36-year-old woman with muscle pain and weakness. Phosphaturic mesenchymal tumor (mixed connective tissue variant)/oncogenic osteomalacia.
Archives of pathology & laboratory medicine 2002;126(10):1245-6.
2002: Jorge S Reis-Filho; Beatriz Torio; André Albergaria; Fernando C Schmitt
p63 expression in normal skin and usual cutaneous carcinomas.
Journal of cutaneous pathology 2002;29(9):517-23.
2002: Roderick H W Simpson; E M Pereira; A C Ribeiro; A Abdulkadir; Jorge S Reis-Filho
Polymorphous low-grade adenocarcinoma of the salivary glands with transformation to high-grade carcinoma.
Histopathology 2002;41(3):250-9.
2002: Jorge S Reis-Filho; André Albergaria; Fernanda Milanezi; Isabel Amendoeira; Fernando C Schmitt
Naked nuclei revisited: p63 Immunoexpression.
Diagnostic cytopathology 2002;27(3):135-8.
2002: Jorge S Reis-Filho; Fernando C Schmitt
Taking advantage of basic research: p63 is a reliable myoepithelial and stem cell marker.
Advances in anatomic pathology 2002;9(5):280-9.
2002: Jorge S Reis-Filho; Conceição Souto-Moura; José Manuel Lopes
Classic Kaposi's sarcoma of the tongue: case report with emphasis on the differential diagnosis.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2002;60(8):951-4.
2002: Jorge S Reis-Filho; Fernando C Schmitt; Maria Fernanda Soares; Teresa M S Figueiredo; José Fillus-Neto
Fine needle aspiration cytology of paratesticular rhabdomyosarcoma mimicking a testicular germ cell tumor.
Acta cytologica 2002;46(4):787-9.
2002: Jorge S Reis-Filho; Teresa M Figueiredo; Fernando C Schmitt
Pathologic quiz case. Multicystic ovarian tumor in a 46-year-old female patient.
Archives of pathology & laboratory medicine 2002;126(7):871, 872.
2002: Carla Costa; Raquel Soares; Jorge S Reis-Filho; Dina Leitão; Isabel Amendoeira; Fernando C Schmitt
Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer.
Journal of clinical pathology 2002;55(6):429-34.
2002: Emílio M Pereira; Sueli A Maeda; Jorge S Reis-Filho
Sarcomatoid variant of anaplastic large cell lymphoma mimicking a primary breast cancer: a challenging diagnosis.
Archives of pathology & laboratory medicine 2002;126(6):723-6.
2002: Jorge S Reis-Filho; Fernanda Milanezi; Fernando C Schmitt
Maspin is expressed in the nuclei of breast myoepithelial cells.
The Journal of pathology 2002;197(2):272-3; author reply 273-4.
2002: José Manuel Lopes; J M Nesland; Jorge S Reis-Filho; R Holm
Differential Ki67 and bcl-2 immunoexpression in solid-glandular and spindle cell components of biphasic synovial sarcoma: a double immunostaining assessment with cytokeratin and vimentin.
Histopathology 2002;40(5):464-71.
2002: Jorge S Reis-Filho; Maria Emília Paiva; José Manuel Lopes
Congenital composite hemangioendothelioma: case report and reappraisal of the hemangioendothelioma spectrum.
Journal of cutaneous pathology 2002;29(4):226-31.
2002: Jorge S Reis-Filho; Joana Cancela Paredes; Fernanda Milanezi; Fernando C Schmitt
Clinicopathologic implications of E-cadherin reactivity in patients with lobular carcinoma in situ of the breast.
Cancer 2002;94(7):2114-5; author reply 2115-6.
2002: Emílio M Pereira; Ieda Millas; Jorge S Reis-Filho; Sueli A Maeda; Marcello Franco
Eosinophilic angiocentric fibrosis of the sinonasal tract: report on the clinicopathologic features of a case and review of the literature.
Head & neck 2002;24(3):307-11.
2002: Jorge S Reis-Filho; Leonora Z B Pope; Cynthia M S R Balderrama; José Fillus-Neto; Fernando C Schmitt
Epithelioid malignant peripheral nerve sheath tumour: case report and review of the previously published cases.
Cytopathology : official journal of the British Society for Clinical Cytology 2002;13(1):54-63.
2002: Jorge S Reis-Filho; Leonora Z B Pope; Fernanda Milanezi; Cynthia M S R Balderrama; Maria José Serapião; Fernando C Schmitt
Primary epithelial malignant mesothelioma of the pericardium with deciduoid features: cytohistologic and immunohistochemical study.
Diagnostic cytopathology 2002;26(2):117-22.
2002: Joana Paredes; Fernanda Milanezi; Jorge S Reis-Filho; Dina Leitão; Daniel Athanazio; Fernando Schmitt
Aberrant P-cadherin expression: is it associated with estrogen-independent growth in breast cancer?
Pathology, research and practice 2002;198(12):795-801.
2002: Jorge S Reis-Filho; Paula Silva; Fernanda Milanezi; José Manuel Lopes
Hyaline cell-rich chondroid syringoma: case report and review of the literature.
Pathology, research and practice 2002;198(11):755-64.
2002: Jorge S Reis-Filho; Fernanda Milanezi; Josefo Ferro; Fernando C Schmitt
Pediatric pigmented dermatofibrosarcoma protuberans (Bednár tumor): case report and review of the literature with emphasis on the differential diagnosis.
Pathology, research and practice 2002;198(9):621-6.
2002: Ana Preto; Jorge S Reis-Filho; Sara Ricardo; Paula Soares
P63 expression in papillary and anaplastic carcinomas of the thyroid gland: lack of an oncogenetic role in tumorigenesis and progression.
Pathology, research and practice 2002;198(7):449-54.
2002: Adelina Gama; Joana Paredes; Maria F Milanezi; Jorge S Reis-Filho; Fatima Gartner; Fernando C Schmitt
P-cadherin expression in canine lactating mammary gland.
Journal of cellular biochemistry 2002;86(3):420-1.
2002: Jorge S Reis-Filho; R Soares; F C Schmitt
Angiogenesis in lymph node metastases.
Histopathology 2002;40(1):103-5.
2002: Jorge S Reis-Filho; Fernanda Milanezi; Maria Fernanda Soares; José Fillus-Neto; Fernando C Schmitt
Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature.
Journal of cutaneous pathology 2002;29(1):59-62.
2002: Hugo Brito; Emílio M Pereira; Jorge S Reis-Filho; Sueli A Maeda
Giant cell collagenoma: case report and review of the literature.
Journal of cutaneous pathology 2002;29(1):48-51.
2002: Raquel Soares; Jorge S Reis-Filho; Fatima Gartner; Fernando C Schmitt
Vascular endothelial growth factor, transforming growth factor-alpha, and estrogen receptors: possible cross-talks and interactions.
The American journal of pathology 2002;160(1):381-2; author reply 382-3.
2001: Carlos R de Medeiros; Luiz F Bleggi-Torres; LN Faoro; Jorge S Reis-Filho; L C Silva; BC de Medeiros; G Loddo; Ricardo Pasquini
Cavernous sinus thrombosis caused by zygomycosis after unrelated bone marrow transplantation.
Transplant infectious disease : an official journal of the Transplantation Society 2001;3(4):231-4.
2001: Ewerton Maggio; Mario Rodrigues Montemor Netto; Emerson Gasparetto; Jorge S Reis-Filho; F A Tironi; Luiz Bleggi Torres
[Cerebrovascular diseases in patients aged 15 to 40 years: neuropathological findings in 47 cases].
Arquivos de neuro-psiquiatria 2001;59(4):920-5.
2001: Jorge S Reis-Filho; Fernando C Schmitt
Amphicrine gastric carcinoma.
Archives of pathology & laboratory medicine 2001;125(11):1513-4.
2001: Jorge S Reis-Filho; LN Faoro; Emerson Gasparetto; J T Totsugui; Fernando C Schmitt
Mammary epithelioid myofibroblastoma arising in bilateral gynecomastia: case report with immunohistochemical profile.
International journal of surgical pathology 2001;9(4):331-4.
2001: Luiz F Bleggi-Torres; Jorge S Reis-Filho; LN Faoro; Lúcia de Noronha; Mario Rodrigues Montemor Netto; Ricardo Ramina
April 2001: a 70 year old woman with recurrent meningioma.
Brain pathology (Zurich, Switzerland) 2001;11(4):481-2, 487.
2001: Jorge S Reis-Filho; Emerson Gasparetto; F C Schmitt; J Fillus-Neto; J S Reis Filho
Pseudoepitheliomatous hyperplasia in cutaneous malignant melanoma: a rare and misleading feature.
Journal of cutaneous pathology 2001;28(9):496-7.
2001: Vânia Oliveira Carvalho; Kerstin Taniguchi; Susana Giraldi; Jeanine Bertogna; Leide Parolin Marinoni; J N Fillus; Jorge S Reis-Filho
Congenital plaquelike glomus tumor in a child.
Pediatric dermatology 2001;18(3):223-6.
2001: Jorge S Reis-Filho; José Fillus-Neto; E Schonemann; AM Sanderson; Fernando C Schmitt
Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study.
Acta cytologica 2001;45(3):407-10.
2001: Jorge S Reis-Filho; F S Schmitt
Reactive spindle cell nodules of the breast.
American journal of clinical pathology 2001;115(5):781-2.
2001: Jorge S Reis-Filho; Fernanda Milanezi; Paula Silva; Fernando C Schmitt
Maspin expression in myoepithelial tumors of the breast.
Pathology, research and practice 2001;197(12):817-21.
2001: Jorge S Reis-Filho; Fernanda Milanezi; Leonora Z B Pope; José Fillus-Neto; Fernando C Schmitt
Primary fibromatosis of the breast in a patient with multiple desmoid tumors--report of a case with evaluation of estrogen and progesterone receptors.
Pathology, research and practice 2001;197(11):775-9.
2000: Jorge S Reis-Filho; Maria F Milanezi; C G Moreira; Lineu César Werneck; P Boscardin; Sérgio Ossamu Ioshii; F C Schmitt
Invasive medullary thymoma associated with Myasthenia gravis: an unusual case.
Arquivos de neuro-psiquiatria 2000;58(4):1110-4.
2000: Mario Rodrigues Montemor Netto; Emerson Gasparetto; LN Faoro; Jorge S Reis-Filho; G S Toni; A D Carvalho Neto; Luiz Bleggi Torres
[Neurocysticercosis: a clinical and pathological study of 27 necropsied cases].
Arquivos de neuro-psiquiatria 2000;58(3B):883-9.
2000: Emerson Gasparetto; LN Faoro; Jorge S Reis-Filho; Luiz Bleggi Torres
[Haemangioblastomas: clinical, epidemiological and pathological findings in 14 cases].
Arquivos de neuro-psiquiatria 2000;58(2A):310-4.
2000: Jorge S Reis-Filho; Emerson Gasparetto; LN Faoro; João Cândido Araújo; Luiz Bleggi Torres
[Medulloblastomas: clinical, epidemiological and pathological findings in 28 cases].
Arquivos de neuro-psiquiatria 2000;58(1):76-80.
2000: Jorge S Reis-Filho; LN Faoro; C Carrilho; Luiz F Bleggi-Torres; Fernando C Schmitt
Evaluation of cell proliferation, epidermal growth factor receptor, and bcl-2 immunoexpression as prognostic factors for patients with World Health Organization grade 2 oligodendroglioma.
Cancer 2000;88(4):862-9.
2000: Jorge S Reis-Filho; C Carrilho; C Valenti; Dina Leitão; C A Ribeiro; S G Ribeiro; Fernando C Schmitt
Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas?
Pathology, research and practice 2000;196(12):835-40.
1999: Luiz Bleggi Torres; Jorge S Reis-Filho; Mario Rodrigues Montemor Netto; LA Dellé; BG Sluminsky; F A Tironi; Affonso Antoniuk; Ricardo Ramina
[Ependymomas: Clinical, epidemiological and clinico-pathological findings of 22 cases].
Arquivos de neuro-psiquiatria 1999;57(2A):261-6.
1999: Luiz Bleggi Torres; Jorge S Reis-Filho; Mario Rodrigues Montemor Netto; LA Dellé; BG Sluminsky; LN Faoro; Affonso Antoniuk; Ricardo Ramina
[Craniopharyngioma: clinical, epidemiological and pathological findings in 25 cases].
Arquivos de neuro-psiquiatria 1999;57(2A):255-60.
1999: Jorge S Reis-Filho; Mario Rodrigues Montemor Netto; BG Sluminsky; LA Dellé; Affonso Antoniuk; Ricardo Ramina; Luiz Bleggi Torres
[Oligodendroglioma: a pathological and clinical study of 15 cases].
Arquivos de neuro-psiquiatria 1999;57(2A):249-54.
1998: Jorge S Reis-Filho; Mario Rodrigues Montemor Netto; J G Loyola Netto; J C de Araújo; Sérgio A Antoniuk; Luiz Bleggi Torres
[Tuberous sclerosis: case report with histopathological and ultrastructural study].
Arquivos de neuro-psiquiatria 1998;56(3B):671-6.
1998: Luiz Bleggi Torres; Jorge S Reis-Filho; Mario Rodrigues Montemor Netto; Lúcia de Noronha; A B Aléssio; Arnolfo de Carvalho Neto
[Infantile desmoplastic ganglioglioma: a clinical, histopathological and epidemiological study of five cases].
Arquivos de neuro-psiquiatria 1998;56(3A):443-8.
1997: Luiz Bleggi Torres; GV Jacob; Jorge S Reis-Filho; Lúcia de Noronha
[Primary pediatric tumours of the central nervous system. Anatomopathological study of 623 cases].
Arquivos de neuro-psiquiatria 1997;55(4):795-800.
1996: Luiz Bleggi Torres; S Bizinelli; B Werner; Jorge S Reis-Filho; J E Telles
[Granular cell tumor of the esophagus: report of two cases with endoscopic removal and immunohistochemistry].
Arquivos de gastroenterologia 1996;33(4):217-20.