Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

John Challis

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Living Beings

Sheep

Chemicals & Drugs

Anatomy

Disorders

Premature Obstetric Labor

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
30
Lye, Stephen
26
Bocking, Alan
24
Yang, Kaiping
19
Gibb, William
16
Alfaidy, Nadia
15
Newnham, John
14
Sloboda, Deborah
12
Patel, Falguni
11
Riley, Simon
11
moss, Timothy
10
Whittle, Wendy
10
Han, V K M
10
Holloway, Alison
9
Matthews, Stephen
7
McDonald, TJ

Sign-in to see all Coauthors

Publications

TOP 3
Dong Xuesen; Yu Celeste; Shynlova Oksana; Challis John R G; Rennie Paul S; Lye Stephen J
p54nrb is a transcriptional corepressor of the progesterone receptor that modulates transcription of the labor-associated gene, connexin 43 (Gja1).
Newnham John P; Pennell Craig E; Lye Stephen J; Rampono Jonathan; Challis John R G
Early life origins of obesity.
Imperatore Alberto; Li Wei; Petraglia Felice; Challis John R G
Urocortin 2 stimulates estradiol secretion from cultured human placental cells: an effect mediated by the type 2 corticotrophin-releasing hormone (CRH) receptor.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of John Challis (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Dong Xuesen; Yu Celeste; Shynlova Oksana; Challis John R G; Rennie Paul S; Lye Stephen J
p54nrb is a transcriptional corepressor of the progesterone receptor that modulates transcription of the labor-associated gene, connexin 43 (Gja1).
Molecular endocrinology (Baltimore, Md.) 2009;23(8):1147-60.
2009: Newnham John P; Pennell Craig E; Lye Stephen J; Rampono Jonathan; Challis John R G
Early life origins of obesity.
Obstetrics and gynecology clinics of North America 2009;36(2):227-44, xii.
2009: Imperatore Alberto; Li Wei; Petraglia Felice; Challis John R G
Urocortin 2 stimulates estradiol secretion from cultured human placental cells: an effect mediated by the type 2 corticotrophin-releasing hormone (CRH) receptor.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(6):551-8.
2009: Connor Kristin L; Bloomfield Frank H; Oliver Mark H; Harding Jane E; Challis John R G
Effect of periconceptional undernutrition in sheep on late gestation expression of mRNA and protein from genes involved in fetal adrenal steroidogenesis and placental prostaglandin production.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(6):573-83.
2009: Yeganegi Maryam; Watson Carole S; Martins Andrew; Kim Sung O; Reid Gregor; Challis John R G; Bocking Alan D
Effect of Lactobacillus rhamnosus GR-1 supernatant and fetal sex on lipopolysaccharide-induced cytokine and prostaglandin-regulating enzymes in human placental trophoblast cells: implications for treatment of bacterial vaginosis and prevention of preterm labor.
American journal of obstetrics and gynecology 2009;200(5):532.e1-8.
2009: Challis John R G; Connor Kristin
Glucocorticoids, 11beta-hydroxysteroid dehydrogenase: mother, fetus, or both?
Endocrinology 2009;150(3):1073-4.
2008: Casciani Valentina; Premyslova Marina; Luo Daochun; Marinoni Emanuela; Moscarini Massimo; Di Iorio Romolo; Challis John R G
Effect of calcium ionophore A23187 on prostaglandin synthase type 2 and 15-hydroxy-prostaglandin dehydrogenase expression in human chorion trophoblast cells.
American journal of obstetrics and gynecology 2008;199(5):554.e1-8.
2008: Gatford Kathryn L; Owens Julie A; Li Shaofu; Moss Timothy J M; Newnham John P; Challis John R G; Sloboda Deborah M
Repeated betamethasone treatment of pregnant sheep programs persistent reductions in circulating IGF-I and IGF-binding proteins in progeny.
American journal of physiology. Endocrinology and metabolism 2008;295(1):E170-8.
2008: Sloboda Deborah M; Moss Timothy J M; Li Shaofu; Matthews Stephen G; Challis John R G; Newnham John P
Expression of glucocorticoid receptor, mineralocorticoid receptor, and 11beta-hydroxysteroid dehydrogenase 1 and 2 in the fetal and postnatal ovine hippocampus: ontogeny and effects of prenatal glucocorticoid exposure.
The Journal of endocrinology 2008;197(2):213-20.
2008: Hill Jacquelyn L; Campbell M Karen; Zou Guang Yong; Challis John R G; Reid Gregor; Chisaka Hiroshi; Bocking Alan D
Prediction of preterm birth in symptomatic women using decision tree modeling for biomarkers.
American journal of obstetrics and gynecology 2008;198(4):468.e1-7; discussion 468.e7-9.
2008: Blank V; Hirsch E; Challis J R G; Romero R; Lye S J
Cytokine signaling, inflammation, innate immunity and preterm labour - a workshop report.
Placenta 2008;29 Suppl A():S102-4.
2008: Sato Kazuyo; Chisaka Hiroshi; Okamura Kunihiro; Challis John R G
Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-Beta dehydrogenase 2 in cultured human term placental trophoblasts.
Biology of reproduction 2008;78(3):514-20.
2008: Casciani Valentina; Marinoni Emanuela; Bocking Alan D; Moscarini Massimo; Di Iorio Romolo; Challis John R G
Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells.
Reproductive sciences (Thousand Oaks, Calif.) 2008;15(1):40-50.
2007: Rac Valeria E; Scott Catherine A; Small Charlene; Adamson S Lee; Rurak Dan; Challis John R; Lye Stephen J
Dose-dependent effects of meloxicam administration on cyclooxygenase-1 and cyclooxygenase-2 protein expression in intrauterine tissues and fetal tissues of a sheep model of preterm labor.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(8):750-64.
2007: King A E; Kelly R W; Sallenave J-M; Bocking A D; Challis J R G
Innate immune defences in the human uterus during pregnancy.
Placenta 2007;28(11-12):1099-106.
2007: Braun Thorsten; Li Shaofu; Moss Timothy J M; Newnham John P; Challis John R G; Gluckman Peter D; Sloboda Deborah M
Maternal betamethasone administration reduces binucleate cell number and placental lactogen in sheep.
The Journal of endocrinology 2007;194(2):337-47.
2007: Donadio S; Alfaidy N; De Keukeleire B; Micoud J; Feige J J; Challis J R G; Benharouga M
Expression and localization of cellular prion and COMMD1 proteins in human placenta throughout pregnancy.
Placenta 2007;28(8-9):907-11.
2007: Dong Xuesen; Sweet Joan; Challis John R G; Brown Theodore; Lye Stephen J
Transcriptional activity of androgen receptor is modulated by two RNA splicing factors, PSF and p54nrb.
Molecular and cellular biology 2007;27(13):4863-75.
2007: Rizek Rose M; Watson Carole S; Keating Sarah; Tai Hsin-Hsiung; Challis John R G; Bocking Alan D
15-Hydroxyprostaglandin dehydrogenase protein expression in human fetal membranes with and without subclinical inflammation.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(3):260-9.
2007: Saunders Sheri; Bocking Alan; Challis John; Reid Gregor
Effect of Lactobacillus challenge on Gardnerella vaginalis biofilms.
Colloids and surfaces. B, Biointerfaces 2007;55(2):138-42.
2007: Li Wei; Unlugedik Elif; Bocking Alan D; Challis John R G
The role of prostaglandins in the mechanism of lipopolysaccharide-induced proMMP9 secretion from human placenta and fetal membrane cells.
Biology of reproduction 2007;76(4):654-9.
2007: King A E; Paltoo A; Kelly R W; Sallenave J-M; Bocking A D; Challis J R G
Expression of natural antimicrobials by human placenta and fetal membranes.
Placenta 2007;28(2-3):161-9.
2007: Sloboda Deborah M; Moss Timothy J M; Li Shaofu; Doherty Dorota; Nitsos Ilias; Challis John R G; Newnham John P
Prenatal betamethasone exposure results in pituitary-adrenal hyporesponsiveness in adult sheep.
American journal of physiology. Endocrinology and metabolism 2007;292(1):E61-70.
2006: Whittle W L; Holloway A C; Lye S; Challis J R G; Gibb W
The pattern of glucocorticoid and estrogen receptors may explain differences in steroid dependency of intrauterine prostaglandin production at parturition in sheep.
Journal of the Society for Gynecologic Investigation 2006;13(7):506-11.
2006: Rac Valeria E; Small Charlene; Scott Catherine A; Adamson S Lee; Rurak Dan; Challis John R; Lye Stephen J
Meloxicam effectively inhibits preterm labor uterine contractions in a chronically catheterized pregnant sheep model: impact on fetal blood flow and fetal-maternal physiologic parameters.
American journal of obstetrics and gynecology 2006;195(2):528-34.
2006: Premyslova M; Chisaka H; Okamura K; Challis J R G
IL-1beta treatment does not co-ordinately up-regulate mPGES-1 and COX-2 mRNA expression, but results in higher degree of cellular and intracellular co-localization of their immunoreactive proteins in human placenta trophoblast cells.
Placenta 2006;27(6-7):576-86.
2006: Jaquiery A L; Oliver M H; Bloomfield F H; Connor K L; Challis J R G; Harding J E
Fetal exposure to excess glucocorticoid is unlikely to explain the effects of periconceptional undernutrition in sheep.
The Journal of physiology 2006;572(Pt 1):109-18.
2005: Challis John R G; Bloomfield Frank H; Bocking Alan D; Casciani Valentina; Chisaka Hiroshi; Connor Kristin; Dong Xuesen; Gluckman Peter; Harding Jane E; Johnstone Jim; Li Wei; Lye Stephen; Okamura Kunihiro; Premyslova Marina
Fetal signals and parturition.
The journal of obstetrics and gynaecology research 2005;31(6):492-9.
2005: Li Wei; Challis John R G
Corticotropin-releasing hormone and urocortin induce secretion of matrix metalloproteinase-9 (MMP-9) without change in tissue inhibitors of MMP-1 by cultured cells from human placenta and fetal membranes.
The Journal of clinical endocrinology and metabolism 2005;90(12):6569-74.
2005: Sloboda Deborah M; Moss Timothy J M; Li Shaofu; Doherty Dorota A; Nitsos Ilias; Challis John R G; Newnham John P
Hepatic glucose regulation and metabolism in adult sheep: effects of prenatal betamethasone.
American journal of physiology. Endocrinology and metabolism 2005;289(4):E721-8.
2005: Chisaka Hiroshi; Johnstone Jim F; Premyslova Marina; Manduch Zuzka; Challis John R G
Effect of pro-inflammatory cytokines on expression and activity of 11beta-hydroxysteroid dehydrogenase type 2 in cultured human term placental trophoblast and human choriocarcinoma JEG-3 cells.
Journal of the Society for Gynecologic Investigation 2005;12(5):303-9.
2005: Johnstone Jim F; Bocking Alan D; Unlugedik Elif; Challis John R G
The effects of chorioamnionitis and betamethasone on 11beta hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor in preterm human placenta.
Journal of the Society for Gynecologic Investigation 2005;12(4):238-45.
2005: Giannoulias D; Haluska G J; Gravett M G; Sadowsky D W; Challis J R G; Novy M J
Localization of prostaglandin H synthase, prostaglandin dehydrogenase, corticotropin releasing hormone and glucocorticoid receptor in rhesus monkey fetal membranes with labor and in the presence of infection.
Placenta 2005;26(4):289-97.
2005: Dong Xuesen; Shylnova Oksana; Challis John R G; Lye Stephen J
Identification and characterization of the protein-associated splicing factor as a negative co-regulator of the progesterone receptor.
The Journal of biological chemistry 2005;280(14):13329-40.
2005: Campbell M Karen; Challis John R G; DaSilva Orlando; Bocking Alan D
A cohort study found that white blood cell count and endocrine markers predicted preterm birth in symptomatic women.
Journal of clinical epidemiology 2005;58(3):304-10.
2005: Challis John R G; Lye Stephen J; Dong X S O
Transcriptional regulation of human myometrium and the onset of labor.
Journal of the Society for Gynecologic Investigation 2005;12(2):65-6.
2005: Kumarasamy Vasumathy; Mitchell Murray D; Bloomfield Frank H; Oliver Mark H; Campbell Melanie E; Challis John R G; Harding Jane E
Effects of periconceptional undernutrition on the initiation of parturition in sheep.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(1):R67-72.
2005: Sloboda D M; Challis J R G; Moss T J M; Newnham J P
Synthetic glucocorticoids: antenatal administration and long-term implications.
Current pharmaceutical design 2005;11(11):1459-72.
2004: Challis John R G
Maternal corticotropin-releasing hormone, fetal growth, and preterm birth.
American journal of obstetrics and gynecology 2004;191(4):1059-60.
2004: Bloomfield Frank H; Oliver Mark H; Hawkins Paul; Holloway Alison C; Campbell Melanie; Gluckman Peter D; Harding Jane E; Challis John R G
Periconceptional undernutrition in sheep accelerates maturation of the fetal hypothalamic-pituitary-adrenal axis in late gestation.
Endocrinology 2004;145(9):4278-85.
2004: Byrne James D; Wing Deborah A; Fraser Mhoyra; Fassett Michael J; Goodwin T Murphy; Challis John R G
Mifepristone: effect on plasma corticotropin-releasing hormone, adrenocorticotropic hormone, and cortisol in term pregnancy.
Journal of perinatology : official journal of the California Perinatal Association 2004;24(7):416-20.
2004: Törnblom Susanne Abelin; Patel Falguni A; Byström Birgitta; Giannoulias Diana; Malmström Anders; Sennström Maria; Lye Stephen J; Challis John R G; Ekman Gunvor
15-hydroxyprostaglandin dehydrogenase and cyclooxygenase 2 messenger ribonucleic acid expression and immunohistochemical localization in human cervical tissue during term and preterm labor.
The Journal of clinical endocrinology and metabolism 2004;89(6):2909-15.
2004: Li Wei; Alfaidy Nadia; Challis John R G
Expression of extracellular matrix metalloproteinase inducer in human placenta and fetal membranes at term labor.
The Journal of clinical endocrinology and metabolism 2004;89(6):2897-904.
2004: Dong X; Challis J R G; Lye S J
Intramolecular interactions between the AF3 domain and the C-terminus of the human progesterone receptor are mediated through two LXXLL motifs.
Journal of molecular endocrinology 2004;32(3):843-57.
2004: Qi Heng; Gervais Michelle L; Li Wei; DeCaprio James A; Challis John R G; Ohh Michael
Molecular cloning and characterization of the von Hippel-Lindau-like protein.
Molecular cancer research : MCR 2004;2(1):43-52.
2004: Mirazi Nasser; Alfaidy Nadia; Martin Rebecca; Challis John R G
Effects of dexamethasone and sulfasalazine on prostaglandin E2 output by human placental cells in vitro.
Journal of the Society for Gynecologic Investigation 2004;11(1):22-6.
2004: Reznikov A G; Challis J R G; Berdusco E T M
Developmental changes in the distribution of corticosteroid-binding globulin in fetal and newborn sheep tissues.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 2004;50(4):92-9.
2003: Premyslova Marina; Li Wei; Alfaidy Nadia; Bocking Alan D; Campbell Karen; Gibb William; Challis John R G
Differential expression and regulation of microsomal prostaglandin E(2) synthase in human fetal membranes and placenta with infection and in cultured trophoblast cells.
The Journal of clinical endocrinology and metabolism 2003;88(12):6040-7.
2003: Alfaidy Nadia; Li Wei; MacIntosh Tracy; Yang Kaiping; Challis John
Late gestation increase in 11beta-hydroxysteroid dehydrogenase 1 expression in human fetal membranes: a novel intrauterine source of cortisol.
The Journal of clinical endocrinology and metabolism 2003;88(10):5033-8.
2003: Bloomfield Frank H; Oliver Mark H; Giannoulias C Diana; Gluckman Peter D; Harding Jane E; Challis John R G
Brief undernutrition in late-gestation sheep programs the hypothalamic-pituitary-adrenal axis in adult offspring.
Endocrinology 2003;144(7):2933-40.
2003: Patel Falguni A; Funder John W; Challis John R G
Mechanism of cortisol/progesterone antagonism in the regulation of 15-hydroxyprostaglandin dehydrogenase activity and messenger ribonucleic acid levels in human chorion and placental trophoblast cells at term.
The Journal of clinical endocrinology and metabolism 2003;88(6):2922-33.
2003: Alfaidy Nadia; Sun Meihua; Challis John R G; Gibb William
Expression of membrane prostaglandin E synthase in human placenta and fetal membranes and effect of labor.
Endocrine 2003;20(3):219-25.
2003: Bloomfield Frank H; Oliver Mark H; Hawkins Paul; Campbell Melanie; Phillips David J; Gluckman Peter D; Challis John R G; Harding Jane E
A periconceptional nutritional origin for noninfectious preterm birth.
Science (New York, N.Y.) 2003;300(5619):606.
2003: Gupta Shalini; Gyomorey Sandor; Lye Stephen J; Gibb William; Challis John R G
Effect of labor on glucocorticoid receptor (GR(Total), GRalpha, and GRbeta) proteins in ovine intrauterine tissues.
Journal of the Society for Gynecologic Investigation 2003;10(3):136-44.
2003: McKeown K J; Challis J R G
Regulation of 15-hydroxy prostaglandin dehydrogenase by corticotrophin-releasing hormone through a calcium-dependent pathway in human chorion trophoblast cells.
The Journal of clinical endocrinology and metabolism 2003;88(4):1737-41.
2003: Gurrin Lyle C; Moss Timothy J; Sloboda Deborah M; Hazelton Martin L; Challis John R G; Newnham John P
Uising WinBUGS to fit nonlinear mixed models with an application to pharmacokinetic modelling of insulin response to glucose challenge in sheep exposed antenatally to glucocorticoids.
Journal of biopharmaceutical statistics 2003;13(1):117-39.
2003: Gupta S; Alfaidy N; Holloway A C; Whittle W L; Lye S J; Gibb W; Challis J R G
Effects of cortisol and oestradiol on hepatic 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor proteins in late-gestation sheep fetus.
The Journal of endocrinology 2003;176(2):175-84.
2002: Sloboda D M; Newnham J P; Challis J R G
Repeated maternal glucocorticoid administration and the developing liver in fetal sheep.
The Journal of endocrinology 2002;175(2):535-43.
2002: Gibb W; Challis J R G
Mechanisms of term and preterm birth.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2002;24(11):874-83.
2002: Giannoulias D; Alfaidy N; Holloway A C; Gibb W; Sun M; Lye S J; Challis J R G
Expression of prostaglandin I(2) synthase, but not prostaglandin E synthase, changes in myometrium of women at term pregnancy.
The Journal of clinical endocrinology and metabolism 2002;87(11):5274-82.
2002: Alfaidy N; Gupta S; DeMarco C; Caniggia I; Challis J R G
Oxygen regulation of placental 11 beta-hydroxysteroid dehydrogenase 2: physiological and pathological implications.
The Journal of clinical endocrinology and metabolism 2002;87(10):4797-805.
2002: Martin R L; Whittle W L; Holloway A C; Gyomorey S; Gibb W; Lye S; Challis J R G
Ontogeny and regulation of ovine placental prostaglandin E2 synthase.
Biology of reproduction 2002;67(3):868-73.
2002: Howe D C; Gertler A; Challis J R G
The late gestation increase in circulating ACTH and cortisol in the fetal sheep is suppressed by intracerebroventricular infusion of recombinant ovine leptin.
The Journal of endocrinology 2002;174(2):259-66.
2002: Challis John R G; Sloboda Deborah M; Alfaidy Nadia; Lye Steven J; Gibb William; Patel Fal A; Whittle Wendy L; Newnham John P
Prostaglandins and mechanisms of preterm birth.
Reproduction (Cambridge, England) 2002;124(1):1-17.
2002: Holloway Alison C; Howe David C; Chan Gabriel; Clifton Vicki L; Smith Roger; Challis John R G
Urocortin: a mechanism for the sustained activation of the HPA axis in the late-gestation ovine fetus?
American journal of physiology. Endocrinology and metabolism 2002;283(1):E165-71.
2002: Xu Ping; Alfaidy Nadia; Challis John R G
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in human placenta and fetal membranes in relation to preterm and term labor.
The Journal of clinical endocrinology and metabolism 2002;87(3):1353-61.
2002: Giannoulias D; Patel F A; Holloway A C; Lye S J; Tai H H; Challis J R G
Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium.
The Journal of clinical endocrinology and metabolism 2002;87(3):1345-52.
2002: Patel Falguni A; Challis John R G
Cortisol/progesterone antagonism in regulation of 15-hydroxysteroid dehydrogenase activity and mRNA levels in human chorion and placental trophoblast cells at term.
The Journal of clinical endocrinology and metabolism 2002;87(2):700-8.
2002: Sloboda D M; Moss T J; Gurrin L C; Newnham J P; Challis J R G
The effect of prenatal betamethasone administration on postnatal ovine hypothalamic-pituitary-adrenal function.
The Journal of endocrinology 2002;172(1):71-81.
2002: Newnham John P; Moss Timothy J M; Nitsos Ilias; Sloboda Deborah M; Challis John R G
Nutrition and the early origins of adult disease.
Asia Pacific journal of clinical nutrition 2002;11 Suppl 3():S537-42.
2001: Challis J R; Sloboda D; Matthews S G; Holloway A; Alfaidy N; Patel F A; Whittle W; Fraser M; Moss T J; Newnham J
The fetal placental hypothalamic-pituitary-adrenal (HPA) axis, parturition and post natal health.
Molecular and cellular endocrinology 2001;185(1-2):135-44.
2001: Alfaidy N; Xiong Z G; Myatt L; Lye S J; MacDonald J F; Challis J R
Prostaglandin F2alpha potentiates cortisol production by stimulating 11beta-hydroxysteroid dehydrogenase 1: a novel feedback loop that may contribute to human labor.
The Journal of clinical endocrinology and metabolism 2001;86(11):5585-92.
2001: Challis J R; Lye S J; Gibb W; Whittle W; Patel F; Alfaidy N
Understanding preterm labor.
Annals of the New York Academy of Sciences 2001;943():225-34.
2001: Moss T J; Sloboda D M; Gurrin L C; Harding R; Challis J R; Newnham J P
Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(3):R960-70.
2001: Challis J
Glucose tolerance in adults after prenatal exposure to famine.
Lancet 2001;357(9270):1798.
2001: Holloway A C; Whittle W L; Challis J R
Effects of cortisol and estradiol on pituitary expression of proopiomelanocortin, prohormone convertase-1, prohormone convertase-2, and glucocorticoid receptor mRNA in fetal sheep.
Endocrine 2001;14(3):343-8.
2001: Whittle W L; Patel F A; Alfaidy N; Holloway A C; Fraser M; Gyomorey S; Lye S J; Gibb W; Challis J R
Glucocorticoid regulation of human and ovine parturition: the relationship between fetal hypothalamic-pituitary-adrenal axis activation and intrauterine prostaglandin production.
Biology of reproduction 2001;64(4):1019-32.
2001: Fraser M; Braems G A; Challis J R;
Developmental regulation of corticotrophin receptor gene expression in the adrenal gland of the ovine fetus and newborn lamb: effects of hypoxia during late pregnancy.
The Journal of endocrinology 2001;169(1):1-10.
2001: Challis J R
Understanding pre-term birth.
Clinical and investigative medicine. Médecine clinique et experimentale 2001;24(1):60-7.
2001: Patel F A; Challis J R
Prostaglandins and uterine activity.
Frontiers of hormone research 2001;27():31-56.
2001: Challis J R; Smith S K
Fetal endocrine signals and preterm labor.
Biology of the neonate 2001;79(3-4):163-7.
2000: McKeown K J; Challis J R; Small C; Adamson L; Bocking A D; Fraser M; Rurak D; Riggs K W; Lye S J
Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam, an inhibitor of prostaglandin synthase-II.
Biology of reproduction 2000;63(6):1899-904.
2000: Challis J; Sloboda D; Matthews S; Holloway A; Alfaidy N; Howe D; Fraser M; Newnham J
Fetal hypothalamic-pituitary adrenal (HPA) development and activation as a determinant of the timing of birth, and of postnatal disease.
Endocrine research 2000;26(4):489-504.
2000: Whittle W L; Holloway A C; Lye S J; Gibb W; Challis J R
Prostaglandin production at the onset of ovine parturition is regulated by both estrogen-independent and estrogen-dependent pathways.
Endocrinology 2000;141(10):3783-91.
2000: Holloway A C; Gyomorey S; Challis J R
Effects of labor on pituitary expression of proopiomelanocortin, prohormone convertase (PC)-1, PC-2, and glucocorticoid receptor mRNA in fetal sheep.
Endocrine 2000;13(1):17-23.
2000: Green L R; Kawagoe Y; Fraser M; Challis J R; Richardson B S
Activation of the hypothalamic-pituitary-adrenal axis with repetitive umbilical cord occlusion in the preterm ovine fetus.
Journal of the Society for Gynecologic Investigation 2000;7(4):224-32.
2000: Gyomorey S; Gupta S; Lye S J; Gibb W; Labrie F; Challis J R
Temporal expression of prostaglandin H synthase type 2 (PGHS-2) and P450(C17)in ovine placentomes with the natural onset of labour.
Placenta 2000;21(5-6):478-86.
2000: Whittle W L; Gibb W; Challis J R
The characterization of human amnion epithelial and mesenchymal cells: the cellular expression, activity and glucocorticoid regulation of prostaglandin output.
Placenta 2000;21(4):394-401.
2000: Sloboda D M; Newnham J P; Challis J R
Effects of repeated maternal betamethasone administration on growth and hypothalamic-pituitary-adrenal function of the ovine fetus at term.
The Journal of endocrinology 2000;165(1):79-91.
2000: Gibb W; Sun M; Gyomorey S; Lye S J; Challis J R
Localization of prostaglandin synthase type-1 (PGHS-1) mRNA and prostaglandin synthase type-2 (PGHS-2) mRNA in ovine myometrium and endometrium throughout gestation.
The Journal of endocrinology 2000;165(1):51-8.
2000: Braems G A; Yao L J; Inchley K; Brickenden A; Han V K; Grolla A; Challis J R; Possmayer F
Ovine surfactant protein cDNAs: use in studies on fetal lung growth and maturation after prolonged hypoxemia.
American journal of physiology. Lung cellular and molecular physiology 2000;278(4):L754-64.
2000: Gyomorey S; Lye S J; Gibb W; Challis J R
Fetal-to-maternal progression of prostaglandin H(2) synthase-2 expression in ovine intrauterine tissues during the course of labor.
Biology of reproduction 2000;62(3):797-805.
2000: Pomini F; Patel F A; Mancuso S; Challis J R
Activity and expression of 15-hydroxyprostaglandin dehydrogenase in cultured chorionic trophoblast and villous trophoblast cells and in chorionic explants at term with and without spontaneous labor.
American journal of obstetrics and gynecology 2000;182(1 Pt 1):221-6.
1999: Jeffray T M; Marinoni E; Ramirez M M; Bocking A D; Challis J R
Effect of prenatal betamethasone administration on maternal and fetal corticosteroid-binding globulin concentrations.
American journal of obstetrics and gynecology 1999;181(6):1546-51.
1999: Pomini F; Caruso A; Challis J R
Interleukin-10 modifies the effects of interleukin-1beta and tumor necrosis factor-alpha on the activity and expression of prostaglandin H synthase-2 and the NAD+-dependent 15-hydroxyprostaglandin dehydrogenase in cultured term human villous trophoblast and chorion trophoblast cells.
The Journal of clinical endocrinology and metabolism 1999;84(12):4645-51.
1999: Norwitz E R; Robinson J N; Challis J R
The control of labor.
The New England journal of medicine 1999;341(9):660-6.
1999: Watson C S; White S E; Homan J H; Kimura K A; Brien J F; Fraher L; Challis J R; Bocking A D
Increased cerebral extracellular adenosine and decreased PGE2 during ethanol-induced inhibition of FBM.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;86(4):1410-20.
1999: Nodwell A; Carmichael L; Fraser M; Challis J; Richardson B
Placental release of corticotrophin-releasing hormone across the umbilical circulation of the human newborn.
Placenta 1999;20(2-3):197-202.
1999: Patel F A; Sun K; Challis J R
Local modulation by 11beta-hydroxysteroid dehydrogenase of glucocorticoid effects on the activity of 15-hydroxyprostaglandin dehydrogenase in human chorion and placental trophoblast cells.
The Journal of clinical endocrinology and metabolism 1999;84(2):395-400.
1999: Sun K; Adamson S L; Yang K; Challis J R
Interconversion of cortisol and cortisone by 11beta-hydroxysteroid dehydrogenases type 1 and 2 in the perfused human placenta.
Placenta 1999;20(1):13-9.
1999: Patel F A; Clifton V L; Chwalisz K; Challis J R
Steroid regulation of prostaglandin dehydrogenase activity and expression in human term placenta and chorio-decidua in relation to labor.
The Journal of clinical endocrinology and metabolism 1999;84(1):291-9.
1999: Bocking A D; Challis J R; Korebrits C
New approaches to the diagnosis of preterm labor.
American journal of obstetrics and gynecology 1999;180(1 Pt 3):S247-8.
1999: Challis J R; Patel F A; Pomini F
Prostaglandin dehydrogenase and the initiation of labor.
Journal of perinatal medicine 1999;27(1):26-34.
1998: Stevens M Y; Challis J R; Lye S J
Corticotropin-releasing hormone receptor subtype 1 is significantly up-regulated at the time of labor in the human myometrium.
The Journal of clinical endocrinology and metabolism 1998;83(11):4107-15.
1998: Braems G A; Han V K; Challis J R
Gestational age-dependent changes in the levels of mRNAs encoding cortisol biosynthetic enzymes and IGF-II in the adrenal gland of fetal sheep during prolonged hypoxemia.
The Journal of endocrinology 1998;159(2):257-64.
1998: Carter A M; Challis J R; Svendsen P
Vasodilator response to exogenous adrenocorticotropic hormone in fetal adrenal cortex precedes increased steroidogenesis in sheep at 105-112 days gestation.
European journal of obstetrics, gynecology, and reproductive biology 1998;81(1):87-94.
1998: Clifton V L; Telfer J F; Thompson A J; Cameron I T; Teoh T G; Lye S J; Challis J R
Corticotropin-releasing hormone and proopiomelanocortin-derived peptides are present in human myometrium.
The Journal of clinical endocrinology and metabolism 1998;83(10):3716-21.
1998: Watson C S; Homan J H; White S E; Challis J R; Bocking A D
Prostaglandin E2 inhibition of fetal breathing movements is not sustained during prolonged reduced uterine blood flow in sheep.
Canadian journal of physiology and pharmacology 1998;76(9):858-66.
1998: Wang S; Matthews S G; Yang K; Challis J R
The effect of estradiol on output of adrenocorticotropin and prolactin by fetal sheep anterior pituitary cells.
Canadian journal of physiology and pharmacology 1998;76(9):843-9.
1998: Challis J; Petraglia F; Chwalisz K
Regulation of term and preterm labour, Castellina, Italy, 28 October-1 November 1997.
Placenta 1998;19(7):551-5.
1998: Sun K; Yang K; Challis J R
Glucocorticoid actions and metabolism in pregnancy: implications for placental function and fetal cardiovascular activity.
Placenta 1998;19(5-6):353-60.
1998: Sun K; Yang K; Challis J R
Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen, and the cyclic adenosine 5'-monophosphate pathway in cultured human placental and chorionic trophoblasts.
Biology of reproduction 1998;58(6):1379-84.
1998: Korebrits C; Yu D H; Ramirez M M; Marinoni E; Bocking A D; Challis J R
Antenatal glucocorticoid administration increases corticotrophin-releasing hormone in maternal plasma.
British journal of obstetrics and gynaecology 1998;105(5):556-61.
1998: Korebrits C; Ramirez M M; Watson L; Brinkman E; Bocking A D; Challis J R
Maternal corticotropin-releasing hormone is increased with impending preterm birth.
The Journal of clinical endocrinology and metabolism 1998;83(5):1585-91.
1998: Marinoni E; Korebrits C; Di Iorio R; Cosmi E V; Challis J R
Effect of betamethasone in vivo on placental corticotropin-releasing hormone in human pregnancy.
American journal of obstetrics and gynecology 1998;178(4):770-8.
1998: Xiao Q; Han X; Arany E; Hill D; Challis J R; McDonald T J
Human placenta and fetal membranes contain peptide YY1-36 and peptide YY3-36.
The Journal of endocrinology 1998;156(3):485-92.
1998: Jeffray T M; Matthews S G; Hammond G L; Challis J R
Divergent changes in plasma ACTH and pituitary POMC mRNA after cortisol administration to late-gestation ovine fetus.
The American journal of physiology 1998;274(3 Pt 1):E417-25.
1998: Challis J R
Molecular aspects of preterm labor.
Bulletin et mémoires de l'Académie royale de médecine de Belgique 1998;153(5-6):263-70; discussion 270-3.
1997: Challis J R
Prostaglandins and reproduction--what do knockouts really tell us?
Nature medicine 1997;3(12):1326-7.
1997: Sun K; Yang K; Challis J R
Differential regulation of 11 beta-hydroxysteroid dehydrogenase type 1 and 2 by nitric oxide in cultured human placental trophoblast and chorionic cell preparation.
Endocrinology 1997;138(11):4912-20.
1997: Fraser M; Matthews S G; Braems G; Jeffray T; Challis J R
Developmental regulation of preproenkephalin (PENK) gene expression in the adrenal gland of the ovine fetus and newborn lamb: effects of hypoxemia and exogenous cortisol infusion.
The Journal of endocrinology 1997;155(1):143-9.
1997: Challis J R; Lye S J; Gibb W
Prostaglandins and parturition.
Annals of the New York Academy of Sciences 1997;828():254-67.
1997: Yang K; Langlois D A; Campbell L E; Challis J R; Krkosek M; Yu M
Cellular localization and developmental regulation of 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) gene expression in the ovine placenta.
Placenta 1997;18(7):503-9.
1997: Matthews S G; Challis J R
CRH and AVP-induced changes in synthesis and release of ACTH from the ovine fetal pituitary in vitro: negative influences of cortisol.
Endocrine 1997;6(3):293-300.
1997: Wang S; Matthews S G; Jeffray T M; Stevens M Y; Yang K; Hammond G L; Challis J R
The effects of estradiol-17 beta infusion into fetal sheep in late gestation.
Endocrine 1997;6(3):271-8.
1997: Han X; Berdusco E T; Lu F; Challis J R
Immunolocalisation of P450(C17) in the fetal sheep adrenal gland during gestation and in response to ACTH and glucocorticoid administration.
Equine veterinary journal. Supplement 1997;(24):62-7.
1997: Gagnon R; Murotsuki J; Challis J R; Fraher L; Richardson B S
Fetal sheep endocrine responses to sustained hypoxemic stress after chronic fetal placental embolization.
The American journal of physiology 1997;272(5 Pt 1):E817-23.
1997: Van Meir C A; Ramirez M M; Matthews S G; Calder A A; Keirse M J; Challis J R
Chorionic prostaglandin catabolism is decreased in the lower uterine segment with term labour.
Placenta 1997;18(2-3):109-14.
1997: van Meir C A; Matthews S G; Keirse M J; Ramirez M M; Bocking A; Challis J R
15-hydroxyprostaglandin dehydrogenase: implications in preterm labor with and without ascending infection.
The Journal of clinical endocrinology and metabolism 1997;82(3):969-76.
1997: Carmichael L; Sadowsky D; Olson D; Challis J; Richardson B
Activation of the fetal hypothalamic-pituitary-adrenal axis with prolonged and graded hypoxemia.
Journal of the Society for Gynecologic Investigation 1997;4(1):8-14.
1997: Murotsuki J; Challis J R; Han V K; Fraher L J; Gagnon R
Chronic fetal placental embolization and hypoxemia cause hypertension and myocardial hypertrophy in fetal sheep.
The American journal of physiology 1997;272(1 Pt 2):R201-7.
1997: Sun K; Yang K; Challis J R
Differential expression of 11 beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes.
The Journal of clinical endocrinology and metabolism 1997;82(1):300-5.
1996: Yang K; Fraser M; Yu M; Krkosek M; Challis J R; Lamming G E; Campbell L E; Darnel A
Pattern of 11 beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression in the ovine uterus during the estrous cycle and pregnancy.
Biology of reproduction 1996;55(6):1231-6.
1996: Murotsuki J; Gagnon R; Matthews S G; Challis J R
Effects of long-term hypoxemia on pituitary-adrenal function in fetal sheep.
The American journal of physiology 1996;271(4 Pt 1):E678-85.
1996: Xiao Q; Han X; Challis J R; Hill D J; Spindel E R; Prasad C J; Akagi K; McDonald T J
Gastrin-releasing peptide-like immunoreactivity is present in human maternal and fetal placental membranes.
The Journal of clinical endocrinology and metabolism 1996;81(10):3766-73.
1996: Matthews S G; Challis J R
Regulation of the hypothalamo-pituitary-adrenocortical axis in fetal sheep.
Trends in endocrinology and metabolism: TEM 1996;7(7):239-46.
1996: Watson C S; White S E; Homan J; Abdollah S; Brien J F; Challis J R; Bocking A D
Fetal breathing is not inhibited by ethanol exposure during prolonged reduced uterine blood flow.
Canadian journal of physiology and pharmacology 1996;74(9):1016-24.
1996: Matthews S G; Fraser M; Challis J R
Dopaminergic regulation of pituitary function in the late-gestation fetal sheep.
The Journal of endocrinology 1996;150(2):187-94.
1996: Richardson B; Korkola S; Asano H; Challis J; Polk D; Fraser M
Regional blood flow and the endocrine response to sustained hypoxemia in the preterm ovine fetus.
Pediatric research 1996;40(2):337-43.
1996: Van Meir C A; Sangha R K; Walton J C; Matthews S G; Keirse M J; Challis J R
Immunoreactive 15-hydroxyprostaglandin dehydrogenase (PGDH) is reduced in fetal membranes from patients at preterm delivery in the presence of infection.
Placenta 1996;17(5-6):291-7.
1996: Braems G A; Matthews S G; Challis J R
Differential regulation of proopiomelanocortin messenger ribonucleic acid in the pars distalis and pars intermedia of the pituitary gland after prolonged hypoxemia in fetal sheep.
Endocrinology 1996;137(7):2731-8.
1996: Han V K; Bassett N; Walton J; Challis J R
The expression of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) genes in the human placenta and membranes: evidence for IGF-IGFBP interactions at the feto-maternal interface.
The Journal of clinical endocrinology and metabolism 1996;81(7):2680-93.
1996: Sun M; Ramirez M; Challis J R; Gibb W
Immunohistochemical localization of the glucocorticoid receptor in human fetal membranes and decidua at term and preterm delivery.
The Journal of endocrinology 1996;149(2):243-8.
1996: Gibb W; Matthews S G; Challis J R
Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation.
Biology of reproduction 1996;54(3):654-9.
1996: Carter A M; Challis J R; Svendsen P
Regional adrenal blood flow responses to adrenocorticotropic hormone after chronic embolization of the fetal placental circulation in sheep.
The Journal of endocrinology 1996;148(3):517-22.
1996: Xiao Q; Challis J R; Fraser M; Wlodek M E; Thorburn G D; Cuttita F; Hill D J; St-Pierre S; Spindel E R; McDonald T J
Locations and molecular forms of gastrin-releasing peptide-like immunoreactive entities in ovine pregnancy.
Peptides 1996;17(3):489-95.
1995: Jeffray T M; Berdusco E T; Wallace M; Fowden A; Challis J R
Effects of incremental cortisol and adrenalectomy on plasma corticosteroid binding capacity in fetal sheep.
Canadian journal of physiology and pharmacology 1995;73(11):1568-73.
1995: Ramirez M M; Fraher L J; Goltzman D; Hendy G N; Matthews S G; Sangha R; Challis J R
Immunoreactive parathyroid hormone-related protein: its association with preterm labor.
European journal of obstetrics, gynecology, and reproductive biology 1995;63(1):21-6.
1995: Carter A M; Challis J R; Svendsen P
Effect of arginine vasopressin on regional adrenal blood flow and plasma cortisol concentration in fetal sheep.
European journal of obstetrics, gynecology, and reproductive biology 1995;62(2):235-9.
1995: Matthews S G; Challis J R
Levels of pro-opiomelanocortin and prolactin mRNA in the fetal sheep pituitary following hypoxaemia and glucocorticoid treatment in late gestation.
The Journal of endocrinology 1995;147(1):139-46.
1995: Challis J R; Matthews S G; Van Meir C; Ramirez M M
Current topic: the placental corticotrophin-releasing hormone-adrenocorticotrophin axis.
Placenta 1995;16(6):481-502.
1995: Carter A M; Homan J; Fraser M; Richardson B S; Challis J R
Inhibition of ACTH secretion blocks hypoxia-induced increase of adrenal cortical blood flow in fetal sheep.
The American journal of physiology 1995;269(3 Pt 1):E598-604.
1995: Murotsuki J; Challis J R; Johnston L; Gagnon R
Increased fetal plasma prostaglandin E2 concentrations during fetal placental embolization in pregnant sheep.
American journal of obstetrics and gynecology 1995;173(1):30-5.
1995: Berdusco E T; Yang K; Hammond G L; Challis J R
Corticosteroid-binding globulin (CBG) production by hepatic and extra-hepatic sites in the ovine fetus; effects of CBG on glucocorticoid negative feedback on pituitary cells in vitro.
The Journal of endocrinology 1995;146(1):121-30.
1995: Challis J R; Andres S F; Catz C S; Fisher S J; Hay W W; Hunt J S; Illsley N P; Thornburg K L
Conference report: placental growth and function.
Placenta 1995;16(5):471-5.
1995: Lü F; Yang K; Han V K; Challis J R
Expression, distribution, regulation and function of IGFs in the ovine fetal pituitary.
Journal of molecular endocrinology 1995;14(3):323-36.
1995: Challis J R; Berdusco E T; Jeffray T M; Yang K; Hammond G L
Corticosteroid-binding globulin (CBG) in fetal development.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):523-7.
1995: Matthews S G; Challis J R
Regulation of CRH and AVP mRNA in the developing ovine hypothalamus: effects of stress and glucocorticoids.
The American journal of physiology 1995;268(6 Pt 1):E1096-107.
1995: Matthews S G; Challis J R
Developmental regulation of preproenkephalin mRNA in the ovine paraventricular nucleus: effects of stress and glucocorticoids.
Brain research. Developmental brain research 1995;86(1-2):259-67.
1995: Challis J R
CRH, a placental clock and preterm labour.
Nature medicine 1995;1(5):416.
1995: Matthews S G; Yang K; Challis J R
Changes in glucocorticoid receptor mRNA in the developing ovine pituitary and the effects of exogenous cortisol.
The Journal of endocrinology 1995;144(3):483-90.
1995: Challis J R; Han X; Matthews S G; Fowden A L; Silver M; Holdstock N; McGladdery A; Ousey J C; Allen W R; Rossdale P D
Immunohistochemical localisation of met-enkephalin in the adrenal gland of the fetal and newborn horse.
Equine veterinary journal 1995;27(2):147-9.
1995: Han X; Fowden A L; Silver M; Holdstock N; McGladdery A J; Ousey J C; Allen W R; Rossdale P D; Challis J R
Immunohistochemical localisation of steroidogenic enzymes and phenylethanolamine-N-methyl-transferase (PNMT) in the adrenal gland of the fetal and newborn foal.
Equine veterinary journal 1995;27(2):140-6.
1995: Yang K; Matthews S G; Challis J R
Developmental and glucocorticoid regulation of pituitary 11 beta-hydroxysteroid dehydrogenase 1 gene expression in the ovine fetus and lamb.
Journal of molecular endocrinology 1995;14(1):109-16.
1995: Matthews S G; Lü F; Yang K; Challis J R
Hypothalamic pituitary adrenal function in the sheep fetus.
Reproduction, fertility, and development 1995;7(3):509-16.
1994: Fraser M; McDonald T J; Spindel E R; Fahy M; Hill D; Challis J R
Gastrin-releasing peptide is produced in the pregnant ovine uterus.
Endocrinology 1994;135(6):2440-5.
1994: Lü F; Yang K; Challis J R
Regulation of ovine fetal pituitary function by corticotrophin-releasing hormone, arginine vasopressin and cortisol in vitro.
The Journal of endocrinology 1994;143(1):199-208.
1994: Yang K; Berdusco E T; Challis J R
Opposite effects of glucocorticoid on hepatic 11 beta-hydroxysteroid dehydrogenase mRNA and activity in fetal and adult sheep.
The Journal of endocrinology 1994;143(1):121-6.
1994: Matthews S G; Han X; Lu F; Challis J R
Developmental changes in the distribution of pro-opiomelanocortin and prolactin mRNA in the pituitary of the ovine fetus and lamb.
Journal of molecular endocrinology 1994;13(2):175-85.
1994: Lü F; Han V K; Milne W K; Fraser M; Carter A M; Berdusco E T; Challis J R
Regulation of insulin-like growth factor-II gene expression in the ovine fetal adrenal gland by adrenocorticotropic hormone and cortisol.
Endocrinology 1994;134(6):2628-35.
1994: Sangha R K; Walton J C; Ensor C M; Tai H H; Challis J R
Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor.
The Journal of clinical endocrinology and metabolism 1994;78(4):982-9.
1994: Berdusco E T; Milne W K; Challis J R
Low-dose cortisol infusion increases plasma corticosteroid-binding globulin (CBG) and the amount of hepatic CBG mRNA in fetal sheep on day 100 of gestation.
The Journal of endocrinology 1994;140(3):425-30.
1994: Gagnon R; Challis J; Johnston L; Fraher L
Fetal endocrine responses to chronic placental embolization in the late-gestation ovine fetus.
American journal of obstetrics and gynecology 1994;170(3):929-38.
1993: Langlois D A; Fraher L J; Khalil M W; Fraser M; Challis J R
Preferential increase in prostaglandin endoperoxide H synthase compared with lipoxygenase activity in sheep placenta and amnion at term pregnancy and after intrafetal glucocorticoid administration.
The Journal of endocrinology 1993;139(2):195-204.
1993: Berdusco E T; Yang K; Challis J R; Hammond G L
Tissue distribution of alpha 1-proteinase inhibitor messenger ribonucleic acid and its regulation by glucocorticoids in fetal and neonatal sheep.
Biology of reproduction 1993;49(4):816-21.
1993: Bocking A D; Sinervo K R; Smith G N; Carmichael L; Challis J R; Olson D M; Brien J F
Increased uteroplacental production of prostaglandin E2 during ethanol infusion.
The American journal of physiology 1993;265(3 Pt 2):R640-5.
1993: Berdusco E T; Hammond G L; Jacobs R A; Grolla A; Akagi K; Langlois D; Challis J R
Glucocorticoid-induced increase in plasma corticosteroid-binding globulin levels in fetal sheep is associated with increased biosynthesis and alterations in glycosylation.
Endocrinology 1993;132(5):2001-8.
1993: Challis J R; Adamsons K; Catz C S; Yaffe S J
Workshop report: biological consequences of early placental loss: report of the meeting, and issues for further investigation San Juan, Puerto Rico 21-23 November 1991.
Placenta 1993;14(3):355-60.
1993: Challis J R; Bassett N; Berdusco E T; Han V K; Lu F; Riley S C; Yang K
Foetal endocrine maturation.
Equine veterinary journal. Supplement 1993;(14):35-40.
1993: Carter A M; Richardson B S; Homan J; Towstoless M; Challis J R
Regional adrenal blood flow responses to adrenocorticotropic hormone in fetal sheep.
The American journal of physiology 1993;264(2 Pt 1):E264-9.
1993: Hill D J; Clemmons D R; Riley S C; Bassett N; Challis J R
Immunohistochemical localization of insulin-like growth factors (IGFs) and IGF binding proteins -1, -2 and -3 in human placenta and fetal membranes.
Placenta 1993;14(1):1-12.
1993: Sinclair N R; Challis J R
Tentativeness and fervor in cell biology require negative and positive feedforward control.
Life sciences 1993;52(25):1985-93.
1993: Riley S C; Bassett N S; Berdusco E T; Yang K; Leystra-Lantz C; Luu-Thé V; Labrie F; Challis J R
Changes in the abundance of mRNA for type-I 3 beta-hydroxysteroid dehydrogenase/delta 5-->delta 4 isomerase in the human placenta and fetal membranes during pregnancy and labor.
Gynecologic and obstetric investigation 1993;35(4):199-203.
1992: Han V K; Lu F; Bassett N; Yang K P; Delhanty P J; Challis J R
Insulin-like growth factor-II (IGF-II) messenger ribonucleic acid is expressed in steroidogenic cells of the developing ovine adrenal gland: evidence of an autocrine/paracrine role for IGF-II.
Endocrinology 1992;131(6):3100-9.
1992: Houghton P E; McDonald T J; Challis J R
Diminished insulinotropic effects of gastrin-releasing peptide in pregnant sheep are reproduced by progesterone treatment of nonpregnant animals.
Endocrinology 1992;131(5):2337-43.
1992: Yang K; Smith C L; Dales D; Hammond G L; Challis J R
Cloning of an ovine 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development.
Endocrinology 1992;131(5):2120-6.
1992: Fraser M; Carter A M; Challis J R; McDonald T J
Gastrin releasing peptide immunoreactivity is present in ovine amniotic fluid and fetal and maternal circulations. MRC Group in Fetal and Neonatal Health and Development.
Endocrinology 1992;131(4):2033-5.
1992: Sug-Tang A; Bocking A D; Brooks A N; Hooper S; White S E; Jacobs R A; Fraher L J; Challis J R
Effects of restricting uteroplacental blood flow on concentrations of corticotrophin-releasing hormone, adrenocorticotrophin, cortisol, and prostaglandin E2 in the sheep fetus during late pregnancy.
Canadian journal of physiology and pharmacology 1992;70(10):1396-402.
1992: Riley S C; Dupont E; Walton J C; Luu-The V; Labrie F; Pelletier G; Challis J R
Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5----delta 4 isomerase in human placenta and fetal membranes throughout gestation.
The Journal of clinical endocrinology and metabolism 1992;75(3):956-61.
1992: Riley S C; Boshier D P; Luu-The V; Labrie F; Challis J R
Immunohistochemical localization of 3 beta-hydroxysteroid/delta 5-delta 4-isomerase, tyrosine hydroxylase and phenylethanolamine N-methyl transferase in adrenal glands of sheep fetuses throughout gestation and in neonates.
Journal of reproduction and fertility 1992;96(1):127-34.
1992: Matsuda Y; Patrick J; Carmichael L; Challis J; Richardson B
Effects of sustained hypoxemia on the sheep fetus at midgestation: endocrine, cardiovascular, and biophysical responses.
American journal of obstetrics and gynecology 1992;167(2):531-40.
1992: Brooks A N; Challis J R
Adrenocorticotrophin responses to hypoxaemia in fetal sheep are sustained in the presence of naloxone.
Journal of developmental physiology 1992;17(5):221-5.
1992: Yang K; Hammond G L; Challis J R
Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary gland and adrenal.
Journal of molecular endocrinology 1992;8(2):173-80.
1992: Houghton P E; Buchan A M; Challis J R
Ontogeny of the distribution and colocalization of calbindin D28K within neural and endocrine cells of the gastrointestinal tract of fetal and neonatal sheep.
Regulatory peptides 1992;37(2):73-83.
1992: Cheung P Y; Walton J C; Tai H H; Riley S C; Challis J R
Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy.
Gynecologic and obstetric investigation 1992;33(3):142-6.
1992: Riley S C; Greer I A; Schembri L A; Challis J R
Dexamethasone inhibits basal and stimulated prostaglandin E2 output from human placental cells by inhibition of prostaglandin H synthase.
Gynecologic and obstetric investigation 1992;33(2):85-9.
1991: Yang K; Challis J R; Han V K; Hammond G L
Pro-opiomelanocortin messenger RNA levels increase in the fetal sheep pituitary during late gestation.
The Journal of endocrinology 1991;131(3):483-9.
1991: Brooks A N; Challis J R
Effects of naloxone on the preparturient increase in adrenocorticotrophin and cortisol in foetal sheep.
Journal of neuroendocrinology 1991;3(4):419-24.
1991: Hooper S B; Bocking A D; White S; Challis J R; Han V K
DNA synthesis is reduced in selected fetal tissues during prolonged hypoxemia.
The American journal of physiology 1991;261(2 Pt 2):R508-14.
1991: Boshier D P; Jacobs R A; Han V K; Smith W; Riley S C; Challis J R
Immunohistochemical localization of prostaglandin H synthase in the sheep placenta from early pregnancy to term.
Biology of reproduction 1991;45(2):322-7.
1991: Lü F; Yang K; Challis J R
Characteristics and developmental changes of corticotrophin-releasing hormone-binding sites in the fetal sheep anterior pituitary gland.
The Journal of endocrinology 1991;130(2):223-9.
1991: Bocking A D; Challis J R; White S E
Effect of acutely-induced lactic acidemia on fetal breathing movements, heart rate, blood pressure, ACTH and cortisol in sheep.
Journal of developmental physiology 1991;16(1):45-50.
1991: Yang K P; Challis J R
Opioid receptors are present in the hypothalamus but not detectable in the anterior pituitary of the developing ovine fetus.
Neuroendocrinology 1991;53(6):623-7.
1991: Riley S C; Walton J C; Herlick J M; Challis J R
The localization and distribution of corticotropin-releasing hormone in the human placenta and fetal membranes throughout gestation.
The Journal of clinical endocrinology and metabolism 1991;72(5):1001-7.
1991: Jacobs R A; Han V K; Hammond G L; Challis J R
Effect of adrenocorticotropin administration on the biosynthesis of corticosteroid-binding globulin in fetal sheep.
Endocrinology 1991;128(4):1960-6.
1991: Riley S C; Challis J R
Corticotrophin-releasing hormone production by the placenta and fetal membranes.
Placenta 1991;12(2):105-19.
1991: Jacobs R A; Oosterhuis J; Porter D G; Lobb D K; Yuzpe A A; Challis J R
Immunoreactive adrenocorticotrophin is present in the ovary and in particular the oocyte of several mammalian species.
Journal of reproduction and fertility 1991;91(1):285-91.
1990: Akagi K; Berdusco E T; Challis J R
Cortisol inhibits ACTH but not the AVP response to hypoxaemia in fetal lambs at days 123-128 of gestation.
Journal of developmental physiology 1990;14(6):319-24.
1990: Akagi K; Challis J R
Hormonal and biophysical responses to acute hypoxemia in fetal sheep at 0.7-0.8 gestation.
Canadian journal of physiology and pharmacology 1990;68(12):1527-32.
1990: Buckrell B C; Gartley C J; Mehren K G; Crawshaw G J; Johnson W H; Barker I K; Balke J; Coghill C; Challis J R; Goodrowe K L
Failure to maintain interspecific pregnancy after transfer of Dall's sheep embryos to domestic ewes.
Journal of reproduction and fertility 1990;90(2):387-94.
1990: Cheung P Y; Walton J C; Tai H H; Riley S C; Challis J R
Immunocytochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, and placenta.
American journal of obstetrics and gynecology 1990;163(5 Pt 1):1445-9.
1990: Akagi K; Challis J R
Threshold of hormonal and biophysical responses to acute hypoxemia in fetal sheep at different gestational ages.
Canadian journal of physiology and pharmacology 1990;68(5):549-55.
1990: Jones S A; Challis J R
Steroid, corticotrophin-releasing hormone, ACTH and prostaglandin interactions in the amnion and placenta of early pregnancy in man.
The Journal of endocrinology 1990;125(1):153-9.
1990: Yang K; Jones S A; Challis J R
Changes in glucocorticoid receptor number in the hypothalamus and pituitary of the sheep fetus with gestational age and after adrenocorticotropin treatment.
Endocrinology 1990;126(1):11-7.
1990: Akagi K; Challis J R
Relationship between blood gas values and hormonal response to acute hypoxemia in fetal sheep.
Gynecologic and obstetric investigation 1990;30(2):65-70.
1990: Jones S A; Challis J R
Effects of corticotropin-releasing hormone and adrenocorticotropin on prostaglandin output by human placenta and fetal membranes.
Gynecologic and obstetric investigation 1990;29(3):165-8.
1989: Wlodek M E; Challis J R; Richardson B; Patrick J
The effects of hypoxemia with progressive acidemia on fetal renal function in sheep.
Journal of developmental physiology 1989;12(6):323-8.
1989: Cheung P Y; Challis J R
Prostaglandin E2 metabolism in the human fetal membranes.
American journal of obstetrics and gynecology 1989;161(6 Pt 1):1580-5.
1989: Challis J R; Hooper S
Birth: outcome of a positive cascade.
Baillière's clinical endocrinology and metabolism 1989;3(3):781-93.
1989: Brooks A N; Challis J R
Effects of CRF, AVP and opioid peptides on pituitary-adrenal responses in sheep.
Peptides 1989;10(6):1291-3.
1989: Houghton P E; McDonald T J; Challis J R
Ontogeny of the insulin response to glucose in fetal and adult sheep.
Canadian journal of physiology and pharmacology 1989;67(10):1288-93.
1989: Brooks A N; Power L A; Jones S A; Yang K P; Challis J R
Controls of corticotrophin-releasing factor output by hypothalamic tissue from fetal sheep in vitro.
The Journal of endocrinology 1989;122(1):15-22.
1989: Van Dijk J P; Challis J R
Control and ontogeny of hypothalamic-pituitary-adrenal function in the fetal rat.
Journal of developmental physiology 1989;12(1):1-9.
1989: Yang K; Challis J R
Fetal and adult sheep adrenal cortical cells contain glucocorticoid receptors.
Biochemical and biophysical research communications 1989;162(2):604-11.
1989: Challis J R; Brooks A N
Maturation and activation of hypothalamic-pituitary adrenal function in fetal sheep.
Endocrine reviews 1989;10(2):182-204.
1989: Jones S A; Schneider H; Challis J R
Vitamin D3 metabolites stimulate prostaglandin production by human fetal membranes and placenta in vitro.
American journal of perinatology 1989;6(2):138-41.
1989: Challis J R; Richardson B S; Homan J; Carmichael L
Adrenocorticotropic hormone, cortisol, and progesterone changes in the lamb during the perinatal period.
American journal of obstetrics and gynecology 1989;160(4):967-72.
1989: Challis J R; Fraher L; Oosterhuis J; White S E; Bocking A D
Fetal and maternal endocrine responses to prolonged reductions in uterine blood flow in pregnant sheep.
American journal of obstetrics and gynecology 1989;160(4):926-32.
1989: Jones S A; Brooks A N; Challis J R
Steroids modulate corticotropin-releasing hormone production in human fetal membranes and placenta.
The Journal of clinical endocrinology and metabolism 1989;68(4):825-30.
1989: Jones S A; Challis J R
Local stimulation of prostaglandin production by corticotropin-releasing hormone in human fetal membranes and placenta.
Biochemical and biophysical research communications 1989;159(1):192-9.
1988: van Dijk J P; Tanswell A K; Challis J R
Insulin-like growth factor (IGF)-II and insulin, but not IGF-I, are mitogenic for fetal rat adrenal cells in vitro.
The Journal of endocrinology 1988;119(3):509-16.
1988: Brooks A N; Challis J R
Exogenous opioid regulation of the hypothalamic-pituitary-adrenal axis in fetal sheep.
The Journal of endocrinology 1988;119(3):389-95.
1988: Vilos G A; Challis J R; Lye S J; Possmayer F; Harding P G
Discordant accelerated pulmonary maturation after adrenocorticotropic hormone-induced labor in twin sheep fetuses.
American journal of obstetrics and gynecology 1988;159(6):1321-6.
1988: Van Dijk J P; Challis J R; Tanswell A K
Basal serum-free culture system which supports growth of fetal rat adrenal cells in primary monolayer cell culture.
Journal of developmental physiology 1988;10(5):399-409.
1988: Wlodek M E; Challis J R; Patrick J
Urethral and urachal urine output to the amniotic and allantoic sacs in fetal sheep.
Journal of developmental physiology 1988;10(4):309-19.
1988: Brooks A N; Challis J R
Regulation of the hypothalamic-pituitary-adrenal axis in birth.
Canadian journal of physiology and pharmacology 1988;66(8):1106-12.
1988: Brooks A N; Hapak L K; Lye S J; Challis J R
The effects of pulsed adrenocorticotropin1-24 administration to one twin on the endocrine and uterine activity changes during twin pregnancy in sheep.
Biology of reproduction 1988;38(1):135-42.
1988: Lye S J; Freitag C L; Challis J R
Ovine fetal urachus--physiological and hormonal control of its contractile activity.
The American journal of physiology 1988;254(1 Pt 2):F25-31.
1988: McDonald T J; Houghton P; Challis J R; Hramiak I M
The effect of gastrin-releasing peptide on the endocrine pancreas.
Annals of the New York Academy of Sciences 1988;547():242-54.
1987: Challis J R; Vaughan M
Steroid synthetic and prostaglandin metabolizing activity is present in different cell populations from human fetal membranes and decidua.
American journal of obstetrics and gynecology 1987;157(6):1474-81.
1987: Norman L J; Challis J R
Dose-dependent effects of arginine vasopressin on endocrine and blood gas responses of fetal sheep during the last third of pregnancy.
Canadian journal of physiology and pharmacology 1987;65(11):2291-6.
1987: Power S G; Challis J R
Steroid production by dispersed cells from fetal membranes and intrauterine tissues of sheep.
Journal of reproduction and fertility 1987;81(1):65-76.
1987: Mitchell B F; Challis J R; Lukash L
Progesterone synthesis by human amnion, chorion, and decidua at term.
American journal of obstetrics and gynecology 1987;157(2):349-53.
1987: Davidson B J; Murray R D; Challis J R; Valenzuela G J
Estrogen, progesterone, prolactin, prostaglandin E2, prostaglandin F2 alpha, 13,14-dihydro-15-keto-prostaglandin F2 alpha, and 6-keto-prostaglandin F1 alpha gradients across the uterus in women in labor and not in labor.
American journal of obstetrics and gynecology 1987;157(1):54-8.
1987: Patrick J; Challis J R; Cross J
Effects of maternal indomethacin administration on fetal breathing movements in sheep.
Journal of developmental physiology 1987;9(3):295-300.
1987: Norman L J; Challis J R
Dexamethasone inhibits ovine corticotrophin-releasing factor (oCRF), arginine vasopressin (AVP), and oCRF + AVP stimulated release of ACTH during the last third of pregnancy in the sheep fetus.
Canadian journal of physiology and pharmacology 1987;65(6):1186-92.
1987: Patrick J; Challis J R; Cross J; Olson D M; Lye S J; Turliuk R
The relationship between fetal breathing movements and prostaglandin E2 during ACTH-induced labour in sheep.
Journal of developmental physiology 1987;9(3):287-93.
1987: Brooks A N; Challis J R; Norman L J
Pituitary and adrenal responses to pulsatile ovine corticotropin-releasing factor administered to fetal sheep.
Endocrinology 1987;120(6):2383-8.
1987: Norman L J; Challis J R
Synergism between systemic corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin release in vivo varies as a function of gestational age in the ovine fetus.
Endocrinology 1987;120(3):1052-8.
1987: Power S G; Challis J R
The effects of gestational age and intrafetal ACTH administration on the concentration of progesterone in the fetal membranes, endometrium, and myometrium of pregnant sheep.
Canadian journal of physiology and pharmacology 1987;65(2):136-40.
1987: Power S G; Challis J R
Tissue-specific concentration changes of estrone and estradiol during spontaneous and ACTH-induced parturition in sheep.
Canadian journal of physiology and pharmacology 1987;65(2):130-5.
1986: Nakla S; Skinner K; Mitchell B F; Challis J R
Changes in prostaglandin transfer across human fetal membranes obtained after spontaneous labor.
American journal of obstetrics and gynecology 1986;155(6):1337-41.
1986: Challis J R; Richardson B S; Rurak D; Wlodek M E; Patrick J E
Plasma adrenocorticotropic hormone and cortisol and adrenal blood flow during sustained hypoxemia in fetal sheep.
American journal of obstetrics and gynecology 1986;155(6):1332-6.
1986: Romano W M; Lukash L A; Challis J R; Mitchell B F
Substrate utilization for estrogen synthesis by human fetal membranes and decidua.
American journal of obstetrics and gynecology 1986;155(6):1170-5.
1986: Challis J R; Lye S J; Welsh J
Ovine fetal adrenal maturation at term and during fetal ACTH administration: evidence that the modulating effect of cortisol may involve cAMP.
Canadian journal of physiology and pharmacology 1986;64(8):1085-90.
1986: Olson D M; Lye S J; Challis J R
Prostaglandin concentrations in ovine maternal and fetal tissues at late gestation.
Pediatric research 1986;20(1):83-6.
1986: Mitchell B F; Lye S J; Lukash L; Challis J R
Androstenedione metabolism in the late gestation sheep fetus.
Endocrinology 1986;118(1):63-8.
1986: Powell W A; Mitchell B F; Challis J R
Effects of steroids on progesterone output by explants of human chorion.
Gynecologic and obstetric investigation 1986;22(2):64-72.
1986: Challis J R; Lye S J
Parturition.
Oxford reviews of reproductive biology 1986;8():61-129.
1986: Powell W A; Challis J R
Influence of 20 alpha-dihydroprogesterone on progesterone output by human chorion explants.
Gynecologic and obstetric investigation 1986;22(2):73-8.
1985: Norman L J; Lye S J; Wlodek M E; Challis J R
Changes in pituitary responses to synthetic ovine corticotrophin releasing factor in fetal sheep.
Canadian journal of physiology and pharmacology 1985;63(11):1398-403.
1985: Vilos G A; Challis J R; Pliagas G A; Lye S L; Possmayer F; Harding P G
Propranolol inhibits the maturational effect of adrenocorticotropin in the fetal sheep lung.
American journal of obstetrics and gynecology 1985;153(4):472-7.
1985: Warrick C; Skinner K; Mitchell B F; Challis J R
Relation between cyclic adenosine monophosphate and prostaglandin output by dispersed cells from human amnion and decidua.
American journal of obstetrics and gynecology 1985;153(1):66-71.
1985: Lye S J; Wlodek M E; Challis J R
Possible role of uterine contractions in the short-term fluctuations of plasma ACTH concentration in fetal sheep.
The Journal of endocrinology 1985;106(2):R9-11.
1985: Challis J R; Huhtanen D; Sprague C; Mitchell B F; Lye S J
Modulation by cortisol of adrenocorticotropin-induced activation of adrenal function in fetal sheep.
Endocrinology 1985;116(6):2267-72.
1985: Challis J R; Nancekievill E A; Lye S J
Possible role of cortisol in the stimulation of cortisol-binding capacity in the plasma of fetal sheep.
Endocrinology 1985;116(3):1139-44.
1985: Skinner K A; Challis J R
Changes in the synthesis and metabolism of prostaglandins by human fetal membranes and decidua at labor.
American journal of obstetrics and gynecology 1985;151(4):519-23.
1985: Olson D M; Lye S J; Skinner K; Challis J R
Prostanoid concentrations in maternal/fetal plasma and amniotic fluid and intrauterine tissue prostanoid output in relation to myometrial contractility during the onset of adrenocorticotropin-induced preterm labor in sheep.
Endocrinology 1985;116(1):389-97.
1984: Adamson S L; Patrick J E; Challis J R
Effects of naloxone on the breathing, electrocortical, heart rate, glucose and cortisol responses to hypoxia in the sheep fetus.
Journal of developmental physiology 1984;6(6):495-507.
1984: Lye S J; Wlodek M E; Challis J R
Relation between fetal arterial PO2 and oxytocin-induced uterine contractions in pregnant sheep.
Canadian journal of physiology and pharmacology 1984;62(10):1337-40.
1984: Lye S J; Challis J R
In vivo adrenocorticotropin (1-24)-induced accumulation of cyclic adenosine monophosphate by ovine fetal adrenal cells is inhibited by concomitant infusion of metopirone.
Endocrinology 1984;115(4):1584-7.
1984: Mitchell B F; Caro J; Cross J; Challis J R
Adrenocorticotropic activity of an extract from sheep placental tissue at term.
American journal of obstetrics and gynecology 1984;150(2):217-22.
1984: Mitchell B F; Cross J; Hobkirk R; Challis J R
Formation of unconjugated estrogens from estrone sulfate by dispersed cells from human fetal membranes and decidua.
The Journal of clinical endocrinology and metabolism 1984;58(5):845-9.
1984: Olson D M; Lye S J; Skinner K; Challis J R
Early changes in prostaglandin concentrations in ovine maternal and fetal plasma, amniotic fluid and from dispersed cells of intrauterine tissues before the onset of ACTH-induced pre-term labour.
Journal of reproduction and fertility 1984;71(1):45-55.
1984: Bousquet J; Lye S J; Challis J R
Comparison of leucine enkephalin and adrenocorticotrophin effects on adrenal function in fetal and adult sheep.
Journal of reproduction and fertility 1984;70(2):499-506.
1984: Challis J R; Mitchell B F; Lye S J
Activation of fetal adrenal function.
Journal of developmental physiology 1984;6(1):93-105.
1983: Lye S J; Carnevale P; Olson D M; Challis J R
Stimulation of ovine myometrial activity by 6-keto prostaglandin E1.
Prostaglandins 1983;26(5):731-43.
1983: Olson D M; Skinner K; Challis J R
Prostaglandin output in relation to parturition by cells dispersed from human intrauterine tissues.
The Journal of clinical endocrinology and metabolism 1983;57(4):694-9.
1983: Vilos G A; Challis J R; Lye S J; Possmayer F; Harding P G
Accelerated prepartum maturation of the fetal sheep lung with physiological doses of andrenocorticotrophin.
Journal of developmental physiology 1983;5(5):341-50.
1983: Olson D M; Opavsky M A; Challis J R
Prostaglandin synthesis by human amnion is dependent upon extracellular calcium.
Canadian journal of physiology and pharmacology 1983;61(9):1089-92.
1983: Manchester E L; Lye S J; Challis J R
Activation of ovine fetal adrenal function by pulsatile or continuous administration of adrenocorticotropin-(1-24). II. Effects on adrenal cell responses in vitro.
Endocrinology 1983;113(2):777-82.
1983: Lye S J; Sprague C L; Mitchell B F; Challis J R
Activation of ovine fetal adrenal function by pulsatile or continuous administration of adrenocorticotropin-(1-24). I. Effects on fetal plasma corticosteroids.
Endocrinology 1983;113(2):770-6.
1983: Lye S J; Sprague C L; Challis J R
Modulation of ovine myometrial activity by estradiol-17 beta. The possible involvement of prostaglandins.
Canadian journal of physiology and pharmacology 1983;61(7):729-35.
1983: Windmoller R; Lye S J; Challis J R
Estradiol modulation of ovine uterine activity.
Canadian journal of physiology and pharmacology 1983;61(7):722-8.
1983: Power S G; Challis J R
Activity of 3 beta-hydroxysteroid dehydrogenase-5,4-en isomerase in chorioallantois and amnion from pregnant sheep.
The Journal of endocrinology 1983;97(3):347-56.
1983: Olson D M; Skinner K; Challis J R
Estradiol-17 beta and 2-hydroxyestradiol-17 beta-induced differential production of prostaglandins by cells dispersed from human intrauterine tissues at parturition.
Prostaglandins 1983;25(5):639-51.
1983: Challis J R; Currie W B
Changes in the responsiveness of adrenal cells from foetal goats at different times during pregnancy.
Acta endocrinologica 1983;102(1):122-8.
1983: Grimshaw R N; Mitchell B F; Challis J R
Steroid modulation of pregnenolone to progesterone conversion by human placental cells in vitro.
American journal of obstetrics and gynecology 1983;145(2):234-8.
1983: Challis J R; Sprague C; Patrick J E
Relation between diurnal changes in peripheral plasma progesterone, cortisol, and estriol in normal women at 30-31, 34-35, and 38-39 weeks of gestation.
Gynecologic and obstetric investigation 1983;16(1):33-44.
1983: Challis J R; Patrick J E
Changes in the diurnal rhythms of plasma cortisol in women during the third trimester of pregnancy.
Gynecologic and obstetric investigation 1983;16(1):27-32.
1982: Challis J R; Manchester E L; Mitchell B F; Patrick J E
Activation of adrenal function in fetal sheep by the infusion of adrenocorticotropin to the fetus in utero.
Biology of reproduction 1982;27(5):1026-32.
1982: Mitchell B; Cruickshank B; McLean D; Challis J
Local modulation of progesterone production in human fetal membranes.
The Journal of clinical endocrinology and metabolism 1982;55(6):1237-9.
1982: Carson G D; Challis J R
Changes in plasma cortisol and progesterone after administration of enkephalins to newborn lambs.
Canadian journal of physiology and pharmacology 1982;60(9):1166-70.
1982: Lye S J; Challis J R
Inhibition by PGI-2 of myometrial activity in vivo in non-pregnant ovariectomized sheep.
Journal of reproduction and fertility 1982;66(1):311-5.
1982: Evans C A; Kennedy T G; Patrick J E; Challis J R
The effects of indomethacin on uterine activity and prostaglandin (PG) concentrations during labor induced by administering ACTH to fetal sheep.
Canadian journal of physiology and pharmacology 1982;60(9):1200-9.
1982: Manchester L; Challis J R
The effects of adrenocorticotropin, guanylylimidodiphosphate, dibutyryl adenosine 3',5'-monophosphate, and exogenous substrates on corticosteroid output by ovine fetal adrenal cells at different times in pregnancy.
Endocrinology 1982;111(3):889-95.
1982: Evans C A; Kennedy T G; Challis J R
Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro.
Biology of reproduction 1982;27(1):1-11.
1982: Evans C A; Kennedy T G; Challis J R
Uterine prostaglandin concentrations following fetal death in sheep.
Prostaglandins 1982;23(3):337-46.
1982: Power S G; Patrick J E; Carson G D; Challis J R
The fetal membranes as a possible source of progesterone in the amniotic and allantoic fluids of pregnant sheep.
Endocrinology 1982;110(2):481-6.
1981: Evans C A; Kennedy T G; Patrick J E; Challis J R
Uterine prostaglandin concentrations in sheep during late pregnancy and adrenocorticotropin-induced labor.
Endocrinology 1981;109(5):1533-8.
1981: Challis J R; Patrick J E
Fetal and maternal estrogen concentrations throughout pregnancy in the sheep.
Canadian journal of physiology and pharmacology 1981;59(9):970-8.
1981: Challis J R; Mitchell B F
Hormonal control of preterm and term parturition.
Seminars in perinatology 1981;5(3):192-202.
1981: Challis J R; Workewych J V; Patrick J E
Diurnal changes in the concentration of progesterone in the plasma of women at 34-35 weeks of gestation.
The Journal of endocrinology 1981;89(3):337-41.
1981: Challis J R; Patrick J E; Cross J; Workewych J; Manchester E; Power S
Short-term fluctuations in the concentration of cortisol and progesterone in fetal plasma, maternal plasma, and amniotic and allantoic fluids from sheep during late pregnancy.
Canadian journal of physiology and pharmacology 1981;59(3):261-7.
1981: Carson G D; Challis J R
Maternal steroid changes after fetal death until delivery of the dead sheep fetus.
Canadian journal of physiology and pharmacology 1981;59(2):168-72.
1981: Carson G D; Challis J R
Adrenal responses to prostaglandin E2 in newborn lambs.
American journal of obstetrics and gynecology 1981;139(3):359-63.
1981: Evans C A; Challis J R; Patrick J E; Garfield R E; Cross J; Workewych J; Manchester L; Sprague C; Lukash L; Crankshaw D; Daniel E E; Johnston A; Kennedy T G
The role and regulation of prostaglandins in late pregnancy and parturition in sheep.
Acta veterinaria Scandinavica. Supplementum 1981;77():251-65.
1981: Challis J R; Manchester E L; Mitchell B F; Patrick J E
The development of fetal adrenal function.
Ciba Foundation symposium 1981;86():43-65.
1980: Power S; Patrick J E; Challis J R
The disposition of [3H]cortisol after intra-amniotic administration to sheep late in pregnancy.
Journal of developmental physiology 1980;2(6):357-63.
1980: Challis J R; Patrick J E; Campbell K; Natale R; Richardson B
Diurnal changes in maternal plasma oestrone and oestradiol at 30 to 31, 34 to 35 and 38 to 39 weeks gestational age.
British journal of obstetrics and gynaecology 1980;87(11):983-8.
1980: Namba Y; Smith J B; Fox G S; Challis J R
Plasma cortisol concentrations during Caesarean section.
British journal of anaesthesia 1980;52(10):1027-32.
1980: Patrick J; Challis J
Measurement of human fetal breathing movements in healthy pregnancies using a real-time scanner.
Seminars in perinatology 1980;4(4):275-86.
1980: Glickman J A; Patrick J E; Challis J R
Increase in the response to adrenocorticotrophin of isolated maternal adrenal cells from sheep in late pregnancy.
The Journal of endocrinology 1980;86(1):93-100.
1980: Glickman J A; Challis J R
The changing response pattern of sheep fetal adrenal cells throughout the course of gestation.
Endocrinology 1980;106(5):1371-6.
1980: Challis J R; Socol M; Murata Y; Manning F A; Martin C B
Diurnal variations in maternal and fetal steroids in pregnant rhesus monkeys.
Endocrinology 1980;106(4):1283-8.
1980: Patrick J; Challis J; Campbell K; Carmichael L; Natale R; Richardson B
Circadian rhythms in maternal plasma cortisol and estriol concentrations at 30 to 31, 34 to 35, and 38 to 39 weeks' gestational age.
American journal of obstetrics and gynecology 1980;136(3):325-34.
1980: Challis J R; Greenblatt E
Metabolism of [3H]oestrone sulphate by fetal membranes, placenta and uterine tissues from pregnant rabbits.
Journal of reproduction and fertility 1980;58(1):13-8.
1980: Challis J R; Patrick J E
The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus.
Seminars in perinatology 1980;4(1):23-33.
1980: Challis J R
Endocrinology of parturition.
Mead Johnson Symposium on Perinatal and Developmental Medicine 1980;(15):8-15.
1980: Challis J R
Endocrinology of late pregnancy and parturition.
International review of physiology 1980;22():277-324.
1979: Garfield R E; Rabideau S; Challis J R; Daniel E E
Hormonal control of gap junction formation in sheep myometrium during parturition.
Biology of reproduction 1979;21(4):999-1007.
1979: Patrick J; Challis J; Natale R; Richardson B
Circadian rhythms in maternal plasma cortisol, estrone, estradiol, and estriol at 34 to 35 weeks' gestation.
American journal of obstetrics and gynecology 1979;135(6):791-8.
1979: Thorburn G D; Challis J R
Endocrine control of parturition.
Physiological reviews 1979;59(4):863-918.
1979: Carson G D; Bolla J D; Challis J R
The availability of cortisol in amniotic fluid to the fetus and chorionic and amniotic membranes.
Endocrinology 1979;104(4):1053-8.
1979: Garfield R E; Rabideau S; Challis J R; Daniel E E
Ultrastructural basis for maintenance and termination of pregnancy.
American journal of obstetrics and gynecology 1979;133(3):308-15.
1979: Glickman J A; Carson G D; Challis J R
Differential effects of synthetic adrenocorticotropin1-24 and alpha-melanocyte-stimulating hormone on adrenal function in human and sheep fetuses.
Endocrinology 1979;104(1):34-9.
1979: Crankshaw D J; Challis J R; Patrick J E; Daniel E E
Calcium regulation in the myometrium of pregnant sheep.
Gynecologic and obstetric investigation 1979;10(6):298-305.
1978: Robinson J S; Chapman R L; Challis J R; Mitchell M D; Thorburn G D
Administration of extra-amniotic arachidonic acid and the suppression of uterine prostaglandin synthesis during pregnancy in the rhesus monkey.
Journal of reproduction and fertility 1978;54(2):369-73.
1978: Challis J R; Manning F A
Control of parturition in subhuman primates.
Seminars in perinatology 1978;2(3):247-60.
1978: Challis J R; Carson G D; Naftolin F
Effect of prostaglandin E2 on the concentration of cortisol in the plasma on newborn lambs.
The Journal of endocrinology 1978;76(1):177-8.
1978: Challis J R; Hart I; Louis T M; Mitchell M D; Jenkin G; Robinson J S; Thorburn G D
Prostaglandins in the sheep fetus: implications for fetal function.
Advances in prostaglandin and thromboxane research 1978;4():115-32.
1977: Bolla J; Carson G D; Challis J R
Conversion of PGE2 to PGF2alpha by fetal sheep blood.
Prostaglandins 1977;14(5):873-9.
1977: Challis J R; Bennett M J
Cortisol binding in human amniotic fluid.
American journal of obstetrics and gynecology 1977;129(6):655-61.
1977: Challis J R; Torosis J D
Is alpha MSH a trophic hormone to adrenal function in the foetus?
Nature 1977;269(5631):818-9.
1977: Kendall J Z; Challis J R; Hart I C; Jones C T; Mitchell M D; Ritchie J W; Robinson J S; Thorburn G D
Steroid and prostaglandin concentrations in the plasma of pregnant ewes during infusion of adrenocorticotrophin or dexamethasone to intact or hypophysectomized foetuses.
The Journal of endocrinology 1977;75(1):59-71.
1977: MacKenzie I Z; Pooley G; Challis J R
Changes in the concentration of cortisol in amniotic fluid after intra-amniotic prostaglandin for midtrimester abortion.
British journal of obstetrics and gynaecology 1977;84(8):608-12.
1977: Louis T M; Parry D M; Robinson J S; Thorburn G D; Challis J R
Effects of exogenous progesterone and oestradiol on prostaglandin F and 13,14-dihydro-15-oxo prostaglandin F2alpha concentrations in uteri and plasma of ovariectomized ewes.
The Journal of endocrinology 1977;73(3):427-39.
1977: Challis J R; Hartley P; Johnson P; Patrick J E; Robinson J S; Thorburn G D
Steroids in the amniotic fluid of the rhesus monkey (Macaca mulatta).
The Journal of endocrinology 1977;73(2):355-63.
1977: Challis J R; Jones C T; Robinson J S; Thorburn G D
Development of fetal pituitary-adrenal function.
Journal of steroid biochemistry 1977;8(5):471-8.
1977: Robinson J S; Challis J R; Pooley G; Thorburn G D
Foetal and maternal cortisol and progesterone and maternal oestradiol in prolonged pregnancy after foetal hypophysectomy in sheep.
The Journal of endocrinology 1977;72(2):241-2.
1977: Thorburn G D; Challis J R; Currie W B
Control of parturition in domestic animals.
Biology of reproduction 1977;16(1):18-27.
1977: Challis J R; Kendall J Z; Robinson J S; Thorburn G D
The regulation of corticosteroids during late pregnancy and their role in parturition.
Biology of reproduction 1977;16(1):57-69.
1977: Erickson G F; Challis J R; Ryan K J
Production of prostaglandin F by rabbit granulosa cells and thecal tissue.
Journal of reproduction and fertility 1977;49(1):133-4.
1976: Louis T M; Challis J R; Robinson J S; Thorburn G D
Rapid increase of foetal corticosteroids after prostaglandin E2.
Nature 1976;264(5588):797-9.
1976: Furr B J; Valcaccia B; Challis J R
The effects of Nolvadex (tamoxifen citrate; ICI 46,474) on pregnancy in rabbits.
Journal of reproduction and fertility 1976;48(2):367-9.
1976: Mitchell M D; Patrick J E; Robinson J S; Thorburn G D; Challis J R
Prostaglandins in the plasma and amniotic fluid of rhesus monkeys during pregnancy and after intra-uterine foetal death.
The Journal of endocrinology 1976;71(1):67-76.
1976: Elvidge H; Challis J R; Robinson J S; Roper C; Thorburn G D
Influence of handling and sedation on plasma cortisol in rhesus monkeys (Macaca mulatta).
The Journal of endocrinology 1976;70(2):325-6.
1976: Challis J R; Louis T M; Robinson J S; Thorburn G D
Progesterone and oestradiol in pituitary, brain and uterine tissues of the sheep.
The Journal of endocrinology 1976;69(3):451-2.
1976: Challis J R; Dilley S R; Robinson J S; Thorburn G D
Prostaglandins in the circulation of the fetal lamb.
Prostaglandins 1976;11(6):1041-52.
1976: Challis J R; Forster C S; Furr B J; Robinson J S; Thorburn G D
Production of prostaglandin Falpha in ewes following luteal regression induced with a prostaglandin analogue, Estrumate (cloprostenol; I.C.I. 80996).
Prostaglandins 1976;11(3):537-43.
1976: Challis J R; Calder A A; Dilley S; Forster C S; Hillier K; Hunter D J; MacKenzie I Z; Thorburn G D
Production of prostaglandins E and Falpha by corpora lutea, corpora albicantes and stroma from the human ovary.
The Journal of endocrinology 1976;68(3):401-8.
1976: Fraser I S; Challis J R; Thorburn G D
Metabolic clearance rate and production rate of oestradiol in conscious rabbits.
The Journal of endocrinology 1976;68(02):313-20.
1976: Patrick J E; Challis J R; Johnson P; Robinson J S; Thorburn G D
Cortisol in amniotic fluid of rhesus monkeys.
The Journal of endocrinology 1976;68(1):161-3.
1976: Robinson J S; Challis J R; Furr B J; Louis T M; Thorburn G D
Is the sheep corpus luteum subject to tonic inhibition during the luteal phase of the estrous cycle?
European journal of obstetrics, gynecology, and reproductive biology 1976;6(4):191-9.
1975: Challis J R; Davies I J; Benirschke K; Hendrickx A G; Ryan K J
Proceedings: Effects of dexamethasone on plasma steroid concentrations and foetal adrenal histology in the pregnant rhesus monkey.
The Journal of endocrinology 1975;65(3):40P-41P.
1975: Challis J R; Davies I J; Ryan K J
The effects of dexamethasone and indomethacin on the outcome of pregnancy in the rabbit.
The Journal of endocrinology 1975;64(2):363-70.
1975: Challis J R; Thorburn G D
Prenatal endocrine function and the initiation of parturition.
British medical bulletin 1975;31(1):57-61.
1975: Challis J R; Davies I J; Benirschke K; Hendrickx A G; Ryan K J
The effects of dexamethasone on the peripheral plasma concentrations of androstenedione, testosterone and cortisol in the pregnant rhesus monkey.
Endocrinology 1975;96(1):185-92.
1974: Illingworth D V; Challis J R; Ackland N; Burton A M; Heap R B; Perry J S
Parturition in the guinea-pig; plasma levels of steroid hormones, steroid-binding proteins, and oxytocin, and the effect of corticosteroids, prostaglandins and adrenocorticotrophin.
The Journal of endocrinology 1974;63(3):557-70.
1974: Stephens D B; Challis J R
The activation of oestrous behaviour and the plasma concentration of unconjugated oestrogens in the pig after subcutaneous implantation of oestradiol-17 beta.
Research in veterinary science 1974;17(3):364-71.
1974: Challis J R; Davies I J; Benirschke K; Hendrickx A G; Ryan K J
The effects of dexamethasone on plasma steroid levels and fetal adrenal histology in the pregnant rhesus monkey.
Endocrinology 1974;95(5):1300-5.
1974: Erickson G F; Challis J R; Ryan K J
A developmental study on the capacity of rabbit granulosa cells to respond to trophic hormones and secrete progesterone in vitro.
Developmental biology 1974;40(2):208-24.
1974: Challis J R; Porter D G; Ryan K J
The effects of prostaglandin F2 alpha and ovariectomy on the peripheral plasma steroid concentrations and the evolution of myometrial activity in the pregnant rabbit.
Endocrinology 1974;95(3):783-92.
1974: Challis J R; Erickson G F; Ryan K J
Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory follicles.
Prostaglandins 1974;7(3):183-93.
1974: Challis J R; Davies I J; Benirschke K; Hendrickx A G; Ryan K J
The concentrations of progesterone, estrone and estradiol-17 beta in the peripheral plasma of the rhesus monkey during the final third of gestation, and after the induction of abortion with PGF 2 alpha.
Endocrinology 1974;96(2):547-53.
1974: Porter D G; Challis J R
Failure of high uterine concentrations of progesterone to inhibit myometrial activity in vivo in the post-partum rat.
Journal of reproduction and fertility 1974;39(1):157-62.
1974: Challis J R; Davies I J; Ryan K J
The concentrations of progesterone, estrone and estradiol-17beta in the myometrium of the pregnant rabbit and their relationship to the peripheral plasma steroid concentrations.
Endocrinology 1974;95(1):160-4.
1974: Challis J R; Davies I J; Hendrickx A G; Ryan K J
Prostaglandin F in the peripheral plasma of the rhesus monkey in normal pregnancy and after the administration of dexamethasone and PGF2 alpha.
Prostaglandins 1974;6(5):389-96.
1974: Challis J R; Harrison F A; Heap R B
The extraction of oestrogens, and the rate of secretion of oestrone and oestradiol-17beta by the uterus in the pregnant sheep.
The Journal of endocrinology 1974;61(2):277-84.
1974: Challis J R; Osathanondh R; Ryan K J; Tulchinsky D
Maternal and fetal plasma prostaglandin levels at vaginal delivery and cesarean section.
Prostaglandins 1974;6(4):281-8.
1974: Butron A M; Illingworth D V; Challis J R; McNeilly A S
Placental transfer of oxytocin in the guinea-pig and its release during parturition.
The Journal of endocrinology 1974;60(3):499-506.
1974: Challis J R; Tulchinsky D
A comparison between the concentration of prostaglandin F in human plasma and serum.
Prostaglandins 1974;5(1):27-31.
1974: Challis J R; Kim C K; Naftolin F; Judd H L; Yen S S; Benirschke K
The concentrations of androgens, oestrogens, progesterone and luteinizing hormone in the serum of foetal calves throughout the course of gestations.
The Journal of endocrinology 1974;60(1):107-15.
1973: Challis J R; Davies J; Ryan K J
The concentrations of progesterone, estrone and estradiol-17 beta in the plasma of pregnant rabbits.
Endocrinology 1973;93(4):971-6.
1973: Challis J R; Harrison F A; Heap R B
The metabolic clearance rate, production rate and conversion ratios of oestrone in the sheep.
The Journal of endocrinology 1973;58(3):435-46.
1973: Illingworth D V; Challis J R
Concentrations of oestrogens and progesterone in the plasma of ovariectomized and ovariectomized Norgestrel-treated pregnant guinea-pigs.
Journal of reproduction and fertility 1973;34(2):289-96.
1973: Challis J R; Linzell J L
Oestrone metabolism in pregnant and lactating goats.
The Journal of endocrinology 1973;57(3):451-7.
1973: Illingworth D V; Ackland N; Burton A M; Challis J R; Heap R B; Perry J S
Studies on the endocrinology of parturition in the guinea-pig.
Journal of reproduction and fertility 1973;33(2):361-2.
1973: Challis J R; Harrison F A; Heap R B
The kinetics of oestradiol -17 metabolism in the sheep.
The Journal of endocrinology 1973;57(1):97-110.
1973: Challis J R
The binding of oestrogens to ovine serum albumin.
The Journal of endocrinology 1973;56(2):319-20.
1972: Challis J R; Illingworth D V
Oestrogens in the pregnant guinea-pig.
Journal of reproduction and fertility 1972;31(3):504-5.
1972: Broad S; Challis J R; Heap R B; Jenkin G; Walters D E
Computer analysis of multiple hormone assays (cortisol, oestrogens, progesterone and LH).
The Journal of physiology 1972;226(2):23P-24P.
1972: Challis J R; Harrison F A; Heap R B; Horton E W; Poyser N L
A possible role of oestrogens in the stimulation of prostaglandin F 2 output at the time of parturition in a sheep.
Journal of reproduction and fertility 1972;30(3):485-8.
1972: Bedford C A; Challis J R; Harrison F A; Heap R B
The rôle of oestrogens and progesterone in the onset of parturition in various species.
Journal of reproduction and fertility. Supplement 1972;16():Suppl 16:1-23.
1971: Challis J R; Heap R B; Illingworth D V
Concentrations of oestrogen and progesterone in the plasma of non-pregnant, pregnant and lactating guinea-pigs.
The Journal of endocrinology 1971;51(2):333-45.
1971: Challis J R; Linzell J L
The concentration of total unconjugated oestrogens in the plasma of pregnant goats.
Journal of reproduction and fertility 1971;26(3):401-4.
1971: Challis J R; Harrison F A; Heap R B
Uterine production of oestrogens and progesterone at parturition in the sheep.
Journal of reproduction and fertility 1971;25(2):306-7.
1971: Illingworth D V; Challis J R; Henville A
Plasma levels of progesterone and oestrogen in the pregnant guinea-pig.
Journal of reproduction and fertility 1971;25(2):305-6.
1971: Challis J R
Sharp increase in free circulating oestrogens immediately before parturition in sheep.
Nature 1971;229(5281):208.
1970: Bolton S R; Challis J R; Heap R B; Henville A; Illingworth D V
Protein-binding assays of ovarian steroid hormones.
The Journal of physiology 1970;210(2):95P-96P.
1970: Challis J R; Harrison F A; Heap R B
Oestrogen metabolism in the ewe during late pregnancy.
The Journal of physiology 1970;210(2):93P-95P.
1970: Challis J R; Illingworth D V
The identification of progesterone in flushings from the reproductive tract of non-pregnant guinea-pigs.
Journal of reproduction and fertility 1970;22(3):583-6.
1970: Challis J R; Harrison F A; Heap R B
Metabolic clearance rates and conversions of oestradiol-17-beta in the sheep.
The Biochemical journal 1970;118(2):11P.

Sign-in to see more