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Juhani Knuuti

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Thor Edvardsen; Juhani Knuuti; Gerald Maurer; Sven Plein; Antti Saraste; Patrizio Lancellotti
The year 2012 in the European Heart Journal - Cardiovascular Imaging: Part I.
Ilkka Heinonen; Robert Boushel; Kimmo Kaskinoro; Jukka Kemppainen; Michael Kjaer; Juhani Knuuti; Henning Langberg; Kari K Kalliokoski
Bone blood flow and metabolism in humans: Effect of muscular exercise and other physiological perturbations.
H Honka; Patricia Iozzo; T Ishizu; A Kirjavainen; Juhani Knuuti; J Mäkinen; Veronica Fagerholm; Amalia Gastaldelli; Jarna C Hannukainen; Vesa Oikonen; P Salminen; Antti Saraste; Minna Soinio; Christoffer Kaj-Johan Stark; M Tarkia; Mika Teräs; Tommi Vähäsilta; Pirjo Nuutila
Validation of [18F]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity.

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All Publications

2013: Thor Edvardsen; Juhani Knuuti; Gerald Maurer; Sven Plein; Antti Saraste; Patrizio Lancellotti
The year 2012 in the European Heart Journal - Cardiovascular Imaging: Part I.
European heart journal cardiovascular Imaging 2013;14(6):509-14.
2013: Ilkka Heinonen; Robert Boushel; Kimmo Kaskinoro; Jukka Kemppainen; Michael Kjaer; Juhani Knuuti; Henning Langberg; Kari K Kalliokoski
Bone blood flow and metabolism in humans: Effect of muscular exercise and other physiological perturbations.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(5):1068-74.
2013: H Honka; Patricia Iozzo; T Ishizu; A Kirjavainen; Juhani Knuuti; J Mäkinen; Veronica Fagerholm; Amalia Gastaldelli; Jarna C Hannukainen; Vesa Oikonen; P Salminen; Antti Saraste; Minna Soinio; Christoffer Kaj-Johan Stark; M Tarkia; Mika Teräs; Tommi Vähäsilta; Pirjo Nuutila
Validation of [18F]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity.
Diabetologia 2013;56(4):893-900.
2013: Silvia Morbelli; Francesco Papadia; Nicola Scopinaro; Maria Teresa Verardi; Gian Franco Adami; Samanta Bodrato; Giovanni Camerini; Selene Capitanio; Renzo Cordera; Patricia Iozzo; Juhani Knuuti; Nobuyuki Kudomi; Cecilia Marini; Michela Massollo; Gianmario Sambuceti
Tissue specificity in fasting glucose utilization in slightly obese diabetic patients submitted to bariatric surgery.
Obesity (Silver Spring, Md.) 2013;21(3):E175-81.
2013: Ilkka Heinonen; Dirk J Duncker; Chunlei Han; Jukka Kemppainen; Juhani Knuuti; Matti Luotolahti; Daphne Merkus; Vesa Oikonen; Anna M Savolainen; Kari K Kalliokoski
Pulmonary blood flow and its distribution in highly trained endurance athletes and healthy control subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 2013;114(3):329-34.
2012: Marco Bucci; Manuela Cabiati; Silvia Del Ry; Ronald Borra; Juhani Knuuti; Romina Maggio; Kjell Någren; Pirjo Nuutila; Lionel H Opie; Uberto Pagotto; Jussi P Pärkkä; Riitta Parkkola; Sara Rigazio; Markku Taittonen; Helena Tuunanen; Tapio Viljanen; Patricia Iozzo
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans.
Cardiovascular therapeutics 2012;30(6):333-41.
2012: Geraint Morton; Michael O'Doherty; Divaka Perera; Paul Schleyer; Andreas Schuster; Stacey Baker; Sally Barrington; Amedeo Chiribiri; Erik Hedström; Shazia T Hussain; Andreas Indermuehle; Masaki Ishida; Juhani Knuuti; Eike Nagel
Quantification of absolute myocardial perfusion in patients with coronary artery disease: comparison between cardiovascular magnetic resonance and positron emission tomography.
Journal of the American College of Cardiology 2012;60(16):1546-55.
2012: Olli Hartiala; Nina Hutri-Kähönen; Markus Juonala; Mika Kähönen; Sakari Kainulainen; Sami Kajander; Juhani Knuuti; Tomi Laitinen; Terho Lehtimäki; Costan G Magnussen; Irina Rinta-Kiikka; Antti Saraste; Heikki Ukkonen; Jorma S A Viikari; Jaakko Hartiala; Olli T Raitakari
Adolescence risk factors are predictive of coronary artery calcification at middle age: the cardiovascular risk in young Finns study.
Journal of the American College of Cardiology 2012;60(15):1364-70.
2012: Antti Saraste; Sergey Nesterov; Chunlei Han; Sami Kajander; Juhani Knuuti
PET: Is myocardial flow quantification a clinical reality?
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2012;19(5):1044-59.
2012: Ilkka Heinonen; Dirk J Duncker; Juhani Knuuti; Kari K Kalliokoski
The effect of acute exercise with increasing workloads on inactive muscle blood flow and its heterogeneity in humans.
European journal of applied physiology 2012;112(10):3503-9.
2012: Hanna-Riikka Lehto; Virva Lepomaki; Pirjo Nuutila; Jussi Pärkkä; Riitta Parkkola; Helena Tuunanen; Ronald Borra; Juhani Knuuti; Patricia Iozzo
Effects of acute and one-week fatty acid lowering on cardiac function and insulin sensitivity in relation with myocardial and muscle fat and adiponectin levels.
The Journal of clinical endocrinology and metabolism 2012;97(9):3277-84.
2012: S Masi; Maria-Aurora Morales; Danilo Neglia; Pirjo Nuutila; S Pardini; C Porciello; Piero A Salvadori; A M Sironi; V Chubuchny; Pietro Di Cecco; M Emdin; Ele Ferrannini; Letizia Guiducci; Juhani Knuuti; Riikka Lautamäki; Patricia Iozzo
Similar patterns of myocardial metabolism and perfusion in patients with type 2 diabetes and heart disease of ischaemic and non-ischaemic origin.
Diabetologia 2012;55(9):2494-500.
2012: Antti Saraste; Juhani Knuuti
Novel CT-based imaging markers for high-risk coronary plaques.
European heart journal cardiovascular Imaging 2012;13(8):633-4.
2012: Antti Saraste; Axel Walch; Axel W Weber; Eliane Weidl; Hans-Jürgen Wester; Moritz Wildgruber; Seppo Ylä-Herttuala; Irene Esposito; Gabriele Hölzlwimmer; Juhani Knuuti; Iina Laitinen; Pia Leppänen; Irina Lisinen; Peter B Luppa; Stephan Nekolla; Markus Schwaiger
Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2012;19(4):775-84.
2012: Juhani Knuuti; Antti Saraste
Advances in clinical application of quantitative myocardial perfusion imaging.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2012;19(4):643-6.
2012: Miikka Tarkia; Mika Teräs; Tuula Tolvanen; Tommi Vähäsilta; Mark A Green; Juhani Knuuti; Vesa Oikonen; Tiina Saanijoki; Antti Saraste; Timo Savunen; Christoffer Kaj-Johan Stark; Marjatta Strandberg; Anne Roivainen
Evaluation of 68Ga-labeled tracers for PET imaging of myocardial perfusion in pigs.
Nuclear medicine and biology 2012;39(5):715-23.
2012: Albert Flotats; Juhani Knuuti; Dominique Le Guludec; Frank M Bengel; Claudio Marcassa
CMR versus SPECT for diagnosis of coronary heart disease.
Lancet 2012;379(9832):2145; author reply 2147-8.
2012: Olli Eskola; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Jan Kiss; Juhani Knuuti; Sami Länkimäki; Päivi Marjamäki; Alexandru Naum; Timo Savunen; Jörgen Bergman; Olof Solin
Novel electrophilic synthesis of 6-[¹⁸F]fluorodopamine and comprehensive biological evaluation.
European journal of nuclear medicine and molecular imaging 2012;39(5):800-10.
2012: Ilkka Heinonen; Robert Boushel; Marco Bucci; Jukka Kemppainen; Juhani Knuuti; Pirjo Nuutila; Kari K Kalliokoski
Regulation of subcutaneous adipose tissue blood flow during exercise in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(6):1059-63.
2012: Andrew J Einstein; Juhani Knuuti
Cardiac imaging: does radiation matter?
European heart journal 2012;33(5):573-8.
2012: Richard T George; Vishal C Mehra; Antti Saraste; Juhani Knuuti
Myocardial perfusion by CT versus hybrid imaging.
Cardiology clinics 2012;30(1):135-46.
2012: Ilkka Heinonen; Robert Boushel; Kimmo Kaskinoro; Jukka Kemppainen; Juhani Knuuti; Pirjo Nuutila; Juha E Peltonen; Hannu Sipilä; Kari K Kalliokoski
Effects of adenosine, exercise, and moderate acute hypoxia on energy substrate utilization of human skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;302(3):R385-90.
2012: Ilkka Heinonen; Jukka Kemppainen; Juhani Knuuti; Sergey Nesterov; Toshihiko Fujimoto; Kari K Kalliokoski
Increasing exercise intensity reduces heterogeneity of glucose uptake in human skeletal muscles.
PloS one 2012;7(12):e52191.
2012: Jan Sundell; Jorma Viikari; Ilkka Kantola; Pirjo Nuutila; Olli T Raitakari; Juhani Knuuti
Both BMI and waist circumference are associated with coronary vasoreactivity in overweight and obese men.
Obesity facts 2012;5(5):693-9.
2012: Tuomas O Kiviniemi; Juhani Knuuti; Juha W Koskenvuo; Subhadeep Paul; Tero Aittokallio; Jaakko J Hartiala; Sirpa Jalkanen; Tuula Janatuinen; Tapani Rönnemaa; Jyri O Toikka; Gennady G Yegutkin; Olli T Raitakari
Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes.
Frontiers in physiology 2012;3():338.
2012: Maija T Mäki; Timo H Mäkikallio; Johanna A Miettinen; Sergey Nesterov; Matti Niemelä; Jussi P Pärkkä; Mikko Pietilä; Marjaana Säily; Antti Saraste; Eeva-Riitta Savolainen; Helena Tuunanen; Heikki Ukkonen; Kari Ylitalo; Ville Aalto; K E Juhani Airaksinen; Heikki V Huikuri; Kari Kervinen; Pirjo Koistinen; Juha W Koskenvuo; Riikka Lautamäki; Juhani Knuuti
Cardiac Function, Perfusion, Metabolism, and Innervation following Autologous Stem Cell Therapy for Acute ST-Elevation Myocardial Infarction. A FINCELL-INSIGHT Sub-Study with PET and MRI.
Frontiers in physiology 2012;3():6.
2012: Oliver Gaemperli; Antti Saraste; Juhani Knuuti
Cardiac hybrid imaging.
European heart journal cardiovascular Imaging 2012;13(1):51-60.
2012: Esa Joutsiniemi; Sami Kajander; Juhani Airaksinen; Jaakko Hartiala; Juha W Koskenvuo; Maija Mäki; Mikko Pietilä; Antti Saraste; Markku Saraste; Heikki Ukkonen; Juhani Knuuti
Resting coronary flow velocity in the functional evaluation of coronary artery stenosis: study on sequential use of computed tomography angiography and transthoracic Doppler echocardiography.
European heart journal cardiovascular Imaging 2012;13(1):79-85.
2011: Sami A Kajander; Juhani Airaksinen; Jaakko Hartiala; Esa Joutsiniemi; Maija Mäki; Mikko Pietilä; Antti Saraste; Markku Saraste; Hannu Sipilä; Mika Teräs; Heikki Ukkonen; Juhani Knuuti
Clinical value of absolute quantification of myocardial perfusion with (15)O-water in coronary artery disease.
Circulation. Cardiovascular imaging 2011;4(6):678-84.
2011: Juhani Knuuti
Are coronary plaque characteristics on computed tomography angiography associated with myocardial perfusion?
Journal of the American College of Cardiology 2011;58(17):1817-8.
2011: Ilkka Heinonen; Kari K Kalliokoski; Jukka Kemppainen; Juhani Knuuti; R Matthew Brothers; Craig G Crandall
Local heating, but not indirect whole body heating, increases human skeletal muscle blood flow.
Journal of applied physiology (Bethesda, Md. : 1985) 2011;111(3):818-24.
2011: Pasquale Perrone-Filardi; Zeljko Reiner; Gianmario Sambuceti; Stephen Schroeder; Joanne D Schuijf; Ernst Van der Wall; Stephan Achenbach; Philip A Kaufmann; Juhani Knuuti; Stefan Möhlenkamp; Michael J Zellweger
Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology.
European heart journal 2011;32(16):1986-93, 1993a, 1993b.
2011: Marco Bucci; Silvia Del Ry; Daniela Giannessi; Ronald Borra; Juhani Knuuti; Romina Maggio; Kjell Någren; Pirjo Nuutila; Vesa Oikonen; Riitta Parkkola; Sara Rigazio; Markku Taittonen; Helena Tuunanen; Tapio Viljanen; Patricia Iozzo
Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities.
American journal of physiology. Endocrinology and metabolism 2011;301(1):E105-12.
2011: Gaetano Nucifora; Martin J Schalij; Joop H M Schreur; Joanne D Schuijf; Laurens F Tops; Serge A I P Trines; Olli Turta; Ernst E van der Wall; Jacob M van Werkhoven; Oliver Gaemperli; Mark W Heijenbrok; J Wouter Jukema; Sami Kajander; Philipp A Kaufmann; Juhani Knuuti; Jeroen J Bax
Relationship between obstructive coronary artery disease and abnormal stress testing in patients with paroxysmal or persistent atrial fibrillation.
The international journal of cardiovascular imaging 2011;27(6):777-85.
2011: Noboru Teramoto; Kazuhiro Koshino; Ikuo Yokoyama; Shigeru Miyagawa; Tsutomu Zeniya; Yoshiyuki Hirano; Hajime Fukuda; Junichiro Enmi; Yoshiki Sawa; Juhani Knuuti; Hidehiro Iida
Experimental pig model of old myocardial infarction with long survival leading to chronic left ventricular dysfunction and remodeling as evaluated by PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(5):761-8.
2011: Johanna M U Silvola; Antti Saraste; Sarita Forsback; V Jukka O Laine; Pekka Saukko; Suvi E Heinonen; Seppo Ylä-Herttuala; Anne Roivainen; Juhani Knuuti
Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(5):1011-5.
2011: Helena Tuunanen; Juhani Knuuti
Metabolic remodelling in human heart failure.
Cardiovascular research 2011;90(2):251-7.
2011: Johanna A Miettinen; Kari Ylitalo; Pirjo Hedberg; Kari Kervinen; Matti Niemelä; Marjaana Säily; Pirjo Koistinen; Eeva-Riitta Savolainen; Heikki Ukkonen; Mikko Pietilä; K E Juhani Airaksinen; Juhani Knuuti; Olli Vuolteenaho; Timo H Mäkikallio; Heikki V Huikuri
Effects of intracoronary injection of autologous bone marrow-derived stem cells on natriuretic peptides and inflammatory markers in patients with acute ST-elevation myocardial infarction.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(4):317-25.
2011: Tuomas O Kiviniemi; Thomas Schindler; Mikko Tulppo; Juhani Knuuti; Olli Raitakari; Juha W Koskenvuo
Cold pressor test safety-the incidence of vasovagal reactions.
The American journal of cardiology 2011;107(3):492-3.
2011: Philipp A Kaufmann; Juhani Knuuti
Ionizing radiation risks of cardiac imaging: estimates of the immeasurable.
European heart journal 2011;32(3):269-71.
2011: Jan Sundell; Antti Ylitalo; Juhani Koistinen; Hanna Laine; K E Juhani Airaksinen; Jeroen J Bax; Erik Engblom; Riikka Kalliokoski; Juhani Knuuti
Increased B-type natriuretic Peptide concentration is associated with reduced coronary vasoreactivity in patients with dilated cardiomyopathy but not in healthy young subjects.
ISRN cardiology 2011;2011():638764.
2011: N Koivuviita; Matti Luotolahti; Juhani Knuuti; Pirjo Nuutila; O Raitakari; Risto Tertti; T Vahlberg; Kaj Metsärinne
The effect of revascularization of atherosclerotic renal artery stenosis on coronary flow reserve and peripheral endothelial function.
Nephron. Clinical practice 2011;118(3):c241-8.
2011: Marco Bucci; Esa Joutsiniemi; Antti Saraste; Sami Kajander; Heikki Ukkonen; Markku Saraste; Mikko Pietilä; Hannu T Sipilä; Mika Teräs; Maija Mäki; K E Juhani Airaksinen; Jaakko Hartiala; Juhani Knuuti; Patricia Iozzo
Intrapericardial, but not extrapericardial, fat is an independent predictor of impaired hyperemic coronary perfusion in coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(1):211-8.
2011: Albert Flotats; Juhani Knuuti; Matthias Gutberlet; Claudio Marcassa; Frank M Bengel; Philippe A Kaufmann; Michael R Rees; Birger Hesse
Hybrid cardiac imaging: SPECT/CT and PET/CT. A joint position statement by the European Association of Nuclear Medicine (EANM), the European Society of Cardiac Radiology (ESCR) and the European Council of Nuclear Cardiology (ECNC).
European journal of nuclear medicine and molecular imaging 2011;38(1):201-12.
2010: Johanna A Miettinen; Riikka J Salonen; Matti Niemelä; Kari Kervinen; Marjaana Säily; Pirjo Koistinen; Eeva-Riitta Savolainen; Heikki Ukkonen; Mikko Pietilä; K E Juhani Airaksinen; Juhani Knuuti; Timo H Mäkikallio; Heikki V Huikuri; Kari Ylitalo
Effects of intracoronary infusion of bone marrow-derived stem cells on pulmonary artery pressure and diastolic function after myocardial infarction.
International journal of cardiology 2010;145(3):631-3.
2010: Maija Bry; Riikka Kivelä; Tanja Holopainen; Andrey Anisimov; Tuomas Tammela; Jarkko Soronen; Johanna Silvola; Antti Saraste; Michael Jeltsch; Petra Korpisalo; Peter Carmeliet; Karl B Lemström; Masabumi Shibuya; Seppo Ylä-Herttuala; Leena Alhonen; Eero Mervaala; Leif C Andersson; Juhani Knuuti; Kari Alitalo
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation.
Circulation 2010;122(17):1725-33.
2010: Philippe Kolh; William Wijns; Nicolas Danchin; Carlo Di Mario; Volkmar Falk; Thierry Folliguet; Scot Garg; Kurt Huber; Stefan James; Juhani Knuuti; Jose Lopez-Sendon; Jean Marco; Lorenzo Menicanti; Miodrag Ostojic; Massimo F Piepoli; Charles Pirlet; Jose L Pomar; Nicolaus Reifart; Flavio L Ribichini; Martin J Schalij; Paul Sergeant; Patrick Washington Serruys; Sigmund Silber; Miguel Sousa Uva; David Taggart
Guidelines on myocardial revascularization.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2010;38 Suppl():S1-S52.
2010: Patricia Iozzo; Marco Bucci; Anne Roivainen; Kjell Någren; Mikko J Järvisalo; Jan Kiss; Letizia Guiducci; Barbara Fielding; Alexandru Naum; Ronald Borra; Kirsi Virtanen; Timo Savunen; Piero A Salvadori; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals.
Gastroenterology 2010;139(3):846-56, 856.e1-6.
2010: S Kajander; E Joutsiniemi; Markku Saraste; Mikko Pietilä; Heikki Ukkonen; A Saraste; H T Sipilä; M Teräs; Maija Mäki; J Airaksinen; Jaakko Hartiala; Juhani Knuuti
Cardiac positron emission tomography/computed tomography imaging accurately detects anatomically and functionally significant coronary artery disease.
Circulation 2010;122(6):603-13.
2010: Marko S Laaksonen; Glenn Björklund; Ilkka Heinonen; Jukka Kemppainen; Juhani Knuuti; Heikki Kyröläinen; Kari K Kalliokoski
Perfusion heterogeneity does not explain excess muscle oxygen uptake during variable intensity exercise.
Clinical physiology and functional imaging 2010;30(4):241-9.
2010: Ilkka H Heinonen; Jukka Kemppainen; Kimmo Kaskinoro; Juha E Peltonen; Ronald Borra; Markus Lindroos; Vesa Oikonen; Pirjo Nuutila; Juhani Knuuti; Robert Boushel; Kari K Kalliokoski
Regulation of human skeletal muscle perfusion and its heterogeneity during exercise in moderate hypoxia.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(1):R72-9.
2010: Sami Kajander; Antti Saraste; Heikki Ukkonen; Juhani Knuuti
Anatomy and function: PET-CT.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2010;6 Suppl G():G87-93.
2010: Antti Saraste; Heikki Ukkonen; Sami Kajander; Juhani Knuuti
Integrated anatomy and viability assessment PET-CT.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2010;6 Suppl G():G132-7.
2010: Iina E K Laitinen; Pauliina Luoto; Kjell Någren; Päivi M Marjamäki; Johanna M U Silvola; Sanna Hellberg; V Jukka O Laine; Seppo Ylä-Herttuala; Juhani Knuuti; Anne Roivainen
Uptake of 11C-choline in mouse atherosclerotic plaques.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(5):798-802.
2010: Margarita Margadán-Méndez; Anu Juslin; Sergey Nesterov; Kari Kalliokoski; Juhani Knuuti; Ulla Ruotsalainen
ICA based automatic segmentation of dynamic H(2)(15)O cardiac PET images.
IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society 2010;14(3):795-802.
2010: Juhani Knuuti; Helena Tuunanen
Metabolic imaging in myocardial ischemia and heart failure.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology 2010;54(2):168-76.
2010: Juha W Koskenvuo; Ilkka Kantola; Pirjo Nuutila; Juhani Knuuti; Riitta Parkkola; Ilkka Mononen; Saija Hurme; Riikka Kalliokoski; Jorma S Viikari; Maria Wendelin-Saarenhovi; Tuomas O Kiviniemi; Jaakko Hartiala
Cardiopulmonary involvement in Fabry's disease.
Acta cardiologica 2010;65(2):185-92.
2010: Johanna A Miettinen; Kari Ylitalo; Pirjo Hedberg; Jari Jokelainen; Kari Kervinen; Matti Niemelä; Marjaana Säily; Pirjo Koistinen; Eeva-Riitta Savolainen; Heikki Ukkonen; Mikko Pietilä; K E Juhani Airaksinen; Juhani Knuuti; Olli Vuolteenaho; Timo H Mäkikallio; Heikki V Huikuri
Determinants of functional recovery after myocardial infarction of patients treated with bone marrow-derived stem cells after thrombolytic therapy.
Heart (British Cardiac Society) 2010;96(5):362-7.
2010: Mika Teräs; Tommi Kokki; Nicolas Durand-Schaefer; Tommi Noponen; Mikko Pietilä; Jan Kiss; Erika Hoppela; Hannu T Sipilä; Juhani Knuuti
Dual-gated cardiac PET-clinical feasibility study.
European journal of nuclear medicine and molecular imaging 2010;37(3):505-16.
2010: Ilkka Heinonen; Jukka Kemppainen; Kimmo Kaskinoro; Juha E Peltonen; Ronald Borra; Markus M Lindroos; Vesa Oikonen; Pirjo Nuutila; Juhani Knuuti; Ylva Hellsten; Robert Boushel; Kari K Kalliokoski
Comparison of exogenous adenosine and voluntary exercise on human skeletal muscle perfusion and perfusion heterogeneity.
Journal of applied physiology (Bethesda, Md. : 1985) 2010;108(2):378-86.
2010: Tommi Kokki; Hannu T Sipilä; Mika Teräs; Tommi Noponen; Nicolas Durand-Schaefer; Riku Klén; Juhani Knuuti
Dual gated PET/CT imaging of small targets of the heart: method description and testing with a dynamic heart phantom.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2010;17(1):71-84.
2009: Seppo Ylä-Herttula; Juhani Knuuti; Anne Roivainen
68Ga-DOTA-RGD peptide: biodistribution and binding into atherosclerotic plaques in mice.
European journal of nuclear medicine and molecular imaging 2009;36(12):2058-67.
2009: Heikki Ukkonen; Laurens Tops; Antti Saraste; Alexandru Naum; Juhani Koistinen; Jeroen Bax; Juhani Knuuti
The effect of right ventricular pacing on myocardial oxidative metabolism and efficiency: relation with left ventricular dyssynchrony.
European journal of nuclear medicine and molecular imaging 2009;36(12):2042-8.
2009: Nobuyuki Kudomi; Mikko J Järvisalo; Jan Kiss; Ronald Borra; Antti Viljanen; Tapio Viljanen; Timo Savunen; Juhani Knuuti; Hidehiro Iida; Pirjo Nuutila; Patricia Iozzo
Non-invasive estimation of hepatic glucose uptake from [18F]FDG PET images using tissue-derived input functions.
European journal of nuclear medicine and molecular imaging 2009;36(12):2014-26.
2009: Patricia Iozzo; Riikka Lautamaki; Ronald Borra; Hanna-Riikka Lehto; Marco Bucci; Antti Viljanen; Jussi Parkka; Virva Lepomaki; Romina Maggio; Riitta Parkkola; Juhani Knuuti; Pirjo Nuutila
Contribution of glucose tolerance and gender to cardiac adiposity.
The Journal of clinical endocrinology and metabolism 2009;94(11):4472-82.
2009: Tiina Marjatta Salo; Jan Sundell; Juhani Knuuti; Jukka Kemppainen; Kira Q Stolen; Pirjo Nuutila; Timo H Mäkikallio; Heikki V Huikuri; K E Juhani Airaksinen
Fractal scaling properties of heart rate dynamics and myocardial efficiency in dilated cardiomyopathy.
Clinical research in cardiology : official journal of the German Cardiac Society 2009;98(11):725-30.
2009: Lionel Henry Opie; Juhani Knuuti
The adrenergic-fatty acid load in heart failure.
Journal of the American College of Cardiology 2009;54(18):1637-46.
2009: Sergey Nesterov; Chunlei Han; Maija Mäki; Sami Kajander; Alexandru Naum; Hans Helenius; Irina Lisinen; Heikki Ukkonen; Mikko Pietilä; Esa Joutsiniemi; Juhani Knuuti
Myocardial perfusion quantitation with 15O-labelled water PET: high reproducibility of the new cardiac analysis software (Carimas).
European journal of nuclear medicine and molecular imaging 2009;36(10):1594-602.
2009: Juhani Knuuti
Integrated positron emission tomography/computed tomography (PET/CT) in coronary disease.
Heart (British Cardiac Society) 2009;95(17):1457-63.
2009: Niina Koivuviita; Risto Tertti; Mikko J Järvisalo; Mikko Pietilä; Jarna Hannukainen; Jan Sundell; Pirjo Nuutila; Juhani Knuuti; Kaj Metsärinne
Increased basal myocardial perfusion in patients with chronic kidney disease without symptomatic coronary artery disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(9):2773-9.
2009: Tiina Ujula; Satu Salomäki; Pauliina Virsu; Petteri Lankinen; Tatu J Mäkinen; Anu Autio; Gennady G Yegutkin; Juhani Knuuti; Sirpa Jalkanen; Anne Roivainen
Synthesis, 68Ga labeling and preliminary evaluation of DOTA peptide binding vascular adhesion protein-1: a potential PET imaging agent for diagnosing osteomyelitis.
Nuclear medicine and biology 2009;36(6):631-41.
2009: Jan Kiss; Alexandru Naum; Nobuyuki Kudomi; Juhani Knuuti; Patricia Iozzo; Timo Savunen; Pirjo Nuutila
Non-invasive diagnosis of acute mesenteric ischaemia using PET.
European journal of nuclear medicine and molecular imaging 2009;36(8):1338-45.
2009: Iina Laitinen; Antti Saraste; Eliane Weidl; Thorsten Poethko; Axel W Weber; Stephan Nekolla; Pia Leppänen; Seppo Ylä-Herttuala; Gabriele Hölzlwimmer; Axel Walch; Irene Esposito; Hans-Jürgen Wester; Juhani Knuuti; Markus Schwaiger
Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.
Circulation. Cardiovascular imaging 2009;2(4):331-8.
2009: Juhani Knuuti; Sami Kajander; Maija Mäki; Heikki Ukkonen
Quantification of myocardial blood flow will reform the detection of CAD.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2009;16(4):497-506.
2009: Antti Viljanen; Anna Karmi; Ronald Borra; Jussi P Pärkkä; Virva Lepomäki; Riitta Parkkola; Riikka Lautamäki; Mikko J Järvisalo; Markku Taittonen; Tapani Rönnemaa; Patricia Iozzo; Juhani Knuuti; Pirjo Nuutila; Olli T Raitakari
Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults.
The American journal of cardiology 2009;103(12):1721-6.
2009: Miikka-Juhani Honka; Markku Vänttinen; Patricia Iozzo; Kirsi A Virtanen; Riikka Lautamäki; Kirsti Hällsten; Ronald J H Borra; Teemu Takala; Antti Viljanen; Jukka Kemppainen; Jussi Pihlajamäki; Juhani Knuuti; Pirjo Nuutila; Markku Laakso
The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2009;58(4):541-6.
2009: Gaetano Nucifora; Joanne D Schuijf; Laurens F Tops; Jacob M van Werkhoven; Sami Kajander; J Wouter Jukema; Joop H M Schreur; Mark W Heijenbrok; Serge A Trines; Oliver Gaemperli; Olli Turta; Philipp A Kaufmann; Juhani Knuuti; Martin J Schalij; Jeroen J Bax
Prevalence of coronary artery disease assessed by multislice computed tomography coronary angiography in patients with paroxysmal or persistent atrial fibrillation.
Circulation. Cardiovascular imaging 2009;2(2):100-6.
2009: Heikki Ukkonen; Keiichiro Yoshinaga; Jean N DaSilva; Rob S B Beanlands; Juhani Knuuti
Cardiovascular drug development using radiopharmaceuticals.
Current pharmaceutical design 2009;15(9):935-42.
2009: Iina Laitinen; Päivi Marjamäki; Kjell Någren; Jukka Laine; Ian Wilson; Pia Leppänen; Seppo Ylä-Herttuala; Anne Roivainen; Juhani Knuuti
Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques.
European journal of nuclear medicine and molecular imaging 2009;36(1):73-80.
2008: Juhani Knuuti
Cardiac hybrid imaging with low radiation dose.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2008;15(6):743-4.
2008: Heikki Ukkonen; Jan Sundell; Juhani Knuuti
Effects of CRT on myocardial innervation, perfusion and metabolism.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2008;10 Suppl 3():iii114-7.
2008: Heikki V Huikuri; Kari Kervinen; Matti Niemelä; Kari Ylitalo; Marjaana Säily; Pirjo Koistinen; Eeva-Riitta Savolainen; Heikki Ukkonen; Mikko Pietilä; Juhani K E Airaksinen; Juhani Knuuti; Timo H Mäkikallio
Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction.
European heart journal 2008;29(22):2723-32.
2008: Ilkka Heinonen; Sergey Nesterov; Kaisa Liukko; Jukka Kemppainen; Kjell Någren; Matti Luotolahti; Pauliina Virsu; Vesa Oikonen; Pirjo Nuutila; Urho M Kujala; Heikki Kainulainen; Robert Boushel; Juhani Knuuti; Kari K Kalliokoski
Myocardial blood flow and adenosine A2A receptor density in endurance athletes and untrained men.
The Journal of physiology 2008;586(Pt 21):5193-202.
2008: Nobuyuki Kudomi; Lotfi Slimani; Mikko J Järvisalo; Jan Kiss; Riikka Lautamäki; G A Naum; Timo Savunen; Juhani Knuuti; Hidehiro Iida; Pirjo Nuutila; Patricia Iozzo
Non-invasive estimation of hepatic blood perfusion from H2 15O PET images using tissue-derived arterial and portal input functions.
European journal of nuclear medicine and molecular imaging 2008;35(10):1899-911.
2008: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Mika Scheinin; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy.
Circulation 2008;118(12):1250-8.
2008: Jeroen J Bax; Otakar Kraft; Alfred E Buxton; Jan Gunnar Fjeld; Petr Parízek; Denis Agostini; Juhani Knuuti; Albert Flotats; James Arrighi; Africa Muxi; Marie-Jeanne Alibelli; Gopa Banerjee; Arnold F Jacobson
123 I-mIBG scintigraphy to predict inducibility of ventricular arrhythmias on cardiac electrophysiology testing: a prospective multicenter pilot study.
Circulation. Cardiovascular imaging 2008;1(2):131-40.
2008: Antti Saraste; Ville Kytö; Iina Laitinen; Markku Saraste; Pia Leppänen; Seppo Ylä-Herttuala; Pekka Saukko; Jaakko Hartiala; Juhani Knuuti
Severe coronary artery stenoses and reduced coronary flow velocity reserve in atherosclerotic mouse model: Doppler echocardiography validation study.
Atherosclerosis 2008;200(1):89-94.
2008: Sara Rigazio; Hanna-Riikka Lehto; Helena Tuunanen; Kjell Någren; Mikko Kankaanpaa; Claudia Simi; Ronald Borra; Alexandru G Naum; Riitta Parkkola; Juhani Knuuti; Pirjo Nuutila; Patricia Iozzo
The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humans.
American journal of physiology. Endocrinology and metabolism 2008;295(2):E413-9.
2008: Juha W Koskenvuo; J J Hartiala; P Nuutila; R Kalliokoski; J S Viikari; E Engblom; M Penttinen; Juhani Knuuti; I Mononen; I M Kantola
Twenty-four-month alpha-galactosidase A replacement therapy in Fabry disease has only minimal effects on symptoms and cardiovascular parameters.
Journal of inherited metabolic disease 2008;31(3):432-41.
2008: Maureen M Henneman; Frank M Bengel; Ernst E van der Wall; Juhani Knuuti; Jeroen J Bax
Cardiac neuronal imaging: application in the evaluation of cardiac disease.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2008;15(3):442-55.
2008: Juhani Knuuti
Should we use more PET-CT in clinical cardiology?
European journal of nuclear medicine and molecular imaging 2008;35(5):887-8.
2008: Teemu Kalliokoski; Pirjo Nuutila; Kirsi A Virtanen; Patricia Iozzo; Marco Bucci; Erkki Svedström; Anne Roivainen; Kjell Någren; Tapio Viljanen; Heikki Minn; Juhani Knuuti; Tapani Rönnemaa; Olli Simell
Pancreatic glucose uptake in vivo in men with newly diagnosed type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2008;93(5):1909-14.
2008: Helena Tuunanen; Heikki Ukkonen; Juhani Knuuti
Myocardial fatty acid metabolism and cardiac performance in heart failure.
Current cardiology reports 2008;10(2):142-8.
2008: Juhani Knuuti; Frank M Bengel
Positron emission tomography and molecular imaging.
Heart (British Cardiac Society) 2008;94(3):360-7.
2008: Juhani Knuuti; Roland Hustinx
Highlights of the annual congress of the European Association of Nuclear Medicine, Copenhagen 2007.
European journal of nuclear medicine and molecular imaging 2008;35(3):655-72.
2008: Denis Agostini; Hein J Verberne; Wolfgang Burchert; Juhani Knuuti; Pavol Povinec; Gianmario Sambuceti; Mustafa Unlu; Montserrat Estorch; Gopa Banerjee; Arnold F Jacobson
I-123-mIBG myocardial imaging for assessment of risk for a major cardiac event in heart failure patients: insights from a retrospective European multicenter study.
European journal of nuclear medicine and molecular imaging 2008;35(3):535-46.
2008: Stephen Schroeder; Stephan Achenbach; Frank M Bengel; Christof Burgstahler; Filippo Cademartiri; Pim de Feyter; Richard T George; Philipp Kaufmann; Andreas F Kopp; Juhani Knuuti; Dieter Ropers; Joanne Schuijf; Laurens F Tops; Jeroen J Bax
Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology.
European heart journal 2008;29(4):531-56.
2008: Juhani Knuuti; Don Poldermans; James E Udelson; Frans J Th Wackers; Jeroen J Bax
Imaging highlights from the European Society of Cardiology, American Society of Nuclear Cardiology, and Heart Failure Society of America.
JACC. Cardiovascular imaging 2008;1(1):119-28.
2007: Ilkka Heinonen; Sergey Nesterov; Jukka Kemppainen; Pirjo Nuutila; Juhani Knuuti; Ruut Laitio; Michael Kjaer; Robert Boushel; Kari K Kalliokoski
Role of adenosine in regulating the heterogeneity of skeletal muscle blood flow during exercise in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(6):2042-8.
2007: Juha W Koskenvuo; Henna Karra; Jaakko Lehtinen; Pekka Niemi; Jussi P Pärkkä; Juhani Knuuti; Jaakko Hartiala
Cardiac MRI: accuracy of simultaneous measurement of left and right ventricular parameters using three different sequences.
Clinical physiology and functional imaging 2007;27(6):385-93.
2007: Mika Teräs; Tuula Tolvanen; J J Johansson; J J Williams; Juhani Knuuti
Performance of the new generation of whole-body PET/CT scanners: Discovery STE and Discovery VCT.
European journal of nuclear medicine and molecular imaging 2007;34(10):1683-92.
2007: Robert B Innis; Vincent J Cunningham; Jacques Delforge; Masahiro Fujita; Albert Gjedde; Roger Gunn; James Holden; Sylvain Houle; Sung-Cheng Huang; Masanori Ichise; Hidehiro Iida; Hiroshi Ito; Yuichi Kimura; Robert A Koeppe; Gitte Moos Knudsen; Juhani Knuuti; Adriaan A Lammertsma; Marc Laruelle; Jean Logan; Ralph Paul Maguire; Mark A Mintun; Evan D Morris; Ramin V Parsey; Julie C Price; Mark Slifstein; Vesna Sossi; Tetsuya Suhara; John R Votaw; Dean F Wong; Richard E Carson
Consensus nomenclature for in vivo imaging of reversibly binding radioligands.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(9):1533-9.
2007: Tuomo Nieminen; Juhani Knuuti; Päivi Hämelahti; Mika Kähönen; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Hannu Jokela; Terho Lehtimäki
Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy.
Vascular pharmacology 2007;47(2-3):113-7.
2007: Marko S Laaksonen; Kari K Kalliokoski; Matti Luotolahti; Jukka Kemppainen; Mika Teräs; Heikki Kyröläinen; Pirjo Nuutila; Juhani Knuuti
Myocardial perfusion during exercise in endurance-trained and untrained humans.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(2):R837-43.
2007: Riikka Lautamäki; Tapani Rönnemaa; Risto Huupponen; Terho Lehtimäki; Patricia Iozzo; K E Juhani Airaksinen; Juhani Knuuti; Pirjo Nuutila
Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease.
Metabolism: clinical and experimental 2007;56(7):881-6.
2007: Juhani Knuuti; Riikka Kalliokoski; Tuula Janatuinen; Jarna C Hannukainen; Kari K Kalliokoski; Juha W Koskenvuo; Stefan Lundt
Effect of estradiol-drospirenone hormone treatment on myocardial perfusion reserve in postmenopausal women with angina pectoris.
The American journal of cardiology 2007;99(12):1648-52.
2007: Paul Knaapen; Juhani Knuuti; Albert C van Rossum
The failing heart.
The New England journal of medicine 2007;356(24):2545; author reply 2546.
2007: Helena Tuunanen; Johanna Kuusisto; Jyri O Toikka; Pertti Jääskeläinen; Päivi Marjamäki; Keijo Peuhkurinen; Tapio Viljanen; Petri Sipola; Kira Q Stolen; Jarna C Hannukainen; Pirjo Nuutila; Markku Laakso; Juhani Knuuti
Myocardial perfusion, oxidative metabolism, and free fatty acid uptake in patients with hypertrophic cardiomyopathy attributable to the Asp175Asn mutation in the alpha-tropomyosin gene: a positron emission tomography study.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2007;14(3):354-65.
2007: Jarna C Hannukainen; Tuula Janatuinen; Jyri O Toikka; Mikko J Järvisalo; Olli Heinonen; Jukka Kapanen; Kjell Någren; Pirjo Nuutila; Urho M Kujala; Jaakko Kaprio; Juhani Knuuti; Kari K Kalliokoski
Myocardial and peripheral vascular functional adaptation to exercise training.
Scandinavian journal of medicine & science in sports 2007;17(2):139-47.
2007: Antti Saraste; Juha W Koskenvuo; Markku Saraste; Jussi P Pärkkä; Jyri O Toikka; Alexandru Naum; Heikki Ukkonen; Juhani Knuuti; Juhani Airaksinen; Jaakko Hartiala
Coronary artery flow velocity profile measured by transthoracic Doppler echocardiography predicts myocardial viability after acute myocardial infarction.
Heart (British Cardiac Society) 2007;93(4):456-7.
2007: Alexandru Naum; Helena Tuunanen; Erik Engblom; Vesa Oikonen; Hannu Sipilä; Patricia Iozzo; Pirjo Nuutila; Juhani Knuuti
Simultaneous evaluation of myocardial blood flow, cardiac function and lung water content using [15O]H2O and positron emission tomography.
European journal of nuclear medicine and molecular imaging 2007;34(4):563-72.
2007: Letizia Guiducci; Tove Grönroos; Mikko J Järvisalo; Jan Kiss; Antti Viljanen; Alexandru Naum; Tapio Viljanen; Timo Savunen; Juhani Knuuti; Ele Ferrannini; Piero A Salvadori; Pirjo Nuutila; Patricia Iozzo
Biodistribution of the fatty acid analogue 18F-FTHA: plasma and tissue partitioning between lipid pools during fasting and hyperinsulinemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(3):455-62.
2007: Paul Knaapen; Tjeerd Germans; Juhani Knuuti; Walter J Paulus; Pieter A Dijkmans; Cornelis P Allaart; Adriaan A Lammertsma; Frans C Visser
Myocardial energetics and efficiency: current status of the noninvasive approach.
Circulation 2007;115(7):918-27.
2007: Patricia Iozzo; Mikko J Jarvisalo; Jan Kiss; Ronald Borra; Gratian A Naum; Antti Viljanen; Tapio Viljanen; Amalia Gastaldelli; Emma Buzzigoli; Letizia Guiducci; Elisabetta Barsotti; Timo Savunen; Juhani Knuuti; Merja Haaparanta-Solin; Ele Ferrannini; Pirjo Nuutila
Quantification of liver glucose metabolism by positron emission tomography: validation study in pigs.
Gastroenterology 2007;132(2):531-42.
2007: E Ilveskoski; Terho Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; R Vesalainen; Pirjo Nuutila; Pekka Laippala; Pekka J Karhunen; Juhani Knuuti
Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype.
Scandinavian journal of clinical and laboratory investigation 2007;67(7):723-34.
2007: Mika Kähönen; T Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; H Laine; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti; Tuomo Nieminen
Angiotensin-converting enzyme gene polymorphism and coronary reactivity in young men.
Scandinavian journal of clinical and laboratory investigation 2007;67(6):596-603.
2007: Mari Luomala; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Marika Saarela; Kari Mattila; M Kalijärvi; Tiina Solakivi; Juhani Knuuti; Mikko Hurme; Terho Lehtimäki
High plasma levels of CD40 are associated with low coenzyme Q and vitamin E content of low-density lipoprotein in healthy men.
Scandinavian journal of clinical and laboratory investigation 2007;67(2):115-22.
2007: Anu Juslin; Jyrki Lötjönen; Sergey Nesterov; Kari K Kalliokoski; Juhani Knuuti; Ulla Ruotsalainen
Alignment of 3-dimensional cardiac structures in O-15-labeled water PET emission images with mutual information.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2007;14(1):82-91.
2007: Jarna C Hannukainen; Pirjo Nuutila; Ronald Borra; Borra Ronald; Jaakko Kaprio; Urho M Kujala; Tuula Janatuinen; Olli Heinonen; Jukka Kapanen; Tapio Viljanen; Merja Haaparanta; Tapani Rönnemaa; Riitta Parkkola; Juhani Knuuti; Kari K Kalliokoski
Increased physical activity decreases hepatic free fatty acid uptake: a study in human monozygotic twins.
The Journal of physiology 2007;578(Pt 1):347-58.
2007: Jeroen J Bax; R S Beanlands; F J Klocke; Juhani Knuuti; Adriaan A Lammertsma; M A Schaefers; H R Schelbert; G K Von Schulthess; Leslee J Shaw; G Z Yang; Paolo G Camici
Diagnostic and clinical perspectives of fusion imaging in cardiology: is the total greater than the sum of its parts?
Heart (British Cardiac Society) 2007;93(1):16-22.
2006: Iina Laitinen; Päivi Marjamäki; Merja Haaparanta; Nina Savisto; Jukka Laine; Sanna L Soini; Ian Wilson; Pia Leppänen; Seppo Ylä-Herttuala; Anne Roivainen; Juhani Knuuti
Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries.
European journal of nuclear medicine and molecular imaging 2006;33(12):1461-7.
2006: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure.
Circulation 2006;114(20):2130-7.
2006: Amir Snapir; Jussi Posti; Erkki Kentala; Juha W Koskenvuo; Jan Sundell; Helena Tuunanen; Kristo Hakala; Harry Scheinin; Juhani Knuuti; Mika Scheinin
Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects.
Anesthesiology 2006;105(5):902-10; quiz 1069-70.
2006: Mikko Kankaanpää; Hanna-Riikka Lehto; Jussi P Pärkkä; Markku Komu; Antti Viljanen; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila; Riitta Parkkola; Patricia Iozzo
Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels.
The Journal of clinical endocrinology and metabolism 2006;91(11):4689-95.
2006: Jarna C Hannukainen; Pirjo Nuutila; Jaakko Kaprio; Olli Heinonen; Urho M Kujala; Tuula Janatuinen; Tapani Rönnemaa; Jukka Kapanen; Merja Haaparanta-Solin; Tapio Viljanen; Juhani Knuuti; Kari K Kalliokoski
Relationship between local perfusion and FFA uptake in human skeletal muscle-no effect of increased physical activity and aerobic fitness.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;101(5):1303-11.
2006: Jan Sundell; Hanna Laine; Olli T Raitakari; Matti Luotolahti; Pirjo Nuutila; Juhani Knuuti
Positive family history of coronary artery disease is associated with reduced myocardial vasoreactivity in healthy men.
International journal of cardiology 2006;112(3):289-94.
2006: Helena Tuunanen; Erik Engblom; Alexandru Naum; Mika Scheinin; Kjell Någren; Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Juhani Knuuti
Decreased myocardial free fatty acid uptake in patients with idiopathic dilated cardiomyopathy: evidence of relationship with insulin resistance and left ventricular dysfunction.
Journal of cardiac failure 2006;12(8):644-52.
2006: Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Hanna Laine; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti; Riikka Rontu; Terho Lehtimäki
The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.
Atherosclerosis 2006;188(2):391-7.
2006: Lotfi Slimani; Vesa Oikonen; Kirsti Hällsten; N Savisto; Juhani Knuuti; Pirjo Nuutila; Patricia Iozzo
Exercise restores skeletal muscle glucose delivery but not insulin-mediated glucose transport and phosphorylation in obese subjects.
The Journal of clinical endocrinology and metabolism 2006;91(9):3394-403.
2006: Alan G Fraser; Peter T Buser; Jeroen J Bax; Willem R Dassen; Petros Nihoyannopoulos; Juerg Schwitter; Juhani Knuuti; Martin Höher; Frank M Bengel; András Szatmári
The future of cardiovascular imaging and non-invasive diagnosis. A joint statement from the European Association of Echocardiography, the Working Groups on Cardiovascular Magnetic Resonance, Computers in Cardiology, and Nuclear Cardiology, of the European Society of Cardiology, the European Association of Nuclear Medicine and the Association for European Paediatric Cardiology.
European journal of nuclear medicine and molecular imaging 2006;33(8):955-9.
2006: Alan G Fraser; Peter T Buser; Jeroen J Bax; Willem R Dassen; Petros Nihoyannopoulos; Juerg Schwitter; Juhani Knuuti; Martin Höher; Frank M Bengel; András Szatmári
The future of cardiovascular imaging and non-invasive diagnosis: a joint statement from the European Association of Echocardiography, the Working Groups on Cardiovascular Magnetic Resonance, Computers in Cardiology, and Nuclear Cardiology, of the European Society of Cardiology, the European Association of Nuclear Medicine, and the Association for European Paediatric Cardiology.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2006;7(4):268-73.
2006: Riikka Lautamäki; Ronald Borra; Patricia Iozzo; Markku Komu; Terho Lehtimäki; Marko Salmi; Sirpa Jalkanen; K E Juhani Airaksinen; Juhani Knuuti; Riitta Parkkola; Pirjo Nuutila
Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes.
American journal of physiology. Endocrinology and metabolism 2006;291(2):E282-90.
2006: Alan G Fraser; Peter T Buser; Jeroen J Bax; Willem R Dassen; Petros Nihoyannopoulos; Juerg Schwitter; Juhani Knuuti; Martin Höher; Frank M Bengel; András Szatmári
The future of cardiovascular imaging and non-invasive diagnosis: a joint statement from the European Association of Echocardiography, the Working Groups on Cardiovascular Magnetic Resonance, Computers in Cardiology, and Nuclear Cardiology, of the European Society of Cardiology, the European Association of Nuclear Medicine, and the Association for European Paediatric Cardiology.
European heart journal 2006;27(14):1750-3.
2006: Patricia Iozzo; Amalia Gastaldelli; Mikko J Järvisalo; Jan Kiss; Ronald Borra; Emma Buzzigoli; Antti Viljanen; G Naum; Tapio Viljanen; Vesa Oikonen; Juhani Knuuti; Timo Savunen; Piero A Salvadori; Ele Ferrannini; Pirjo Nuutila
18F-FDG assessment of glucose disposal and production rates during fasting and insulin stimulation: a validation study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(6):1016-22.
2006: Letizia Guiducci; Mikko J Järvisalo; Jan Kiss; Kjell Någren; Antti Viljanen; Alexandru Naum; Amalia Gastaldelli; Timo Savunen; Juhani Knuuti; Piero A Salvadori; Ele Ferrannini; Pirjo Nuutila; Patricia Iozzo
[11C]palmitate kinetics across the splanchnic bed in arterial, portal and hepatic venous plasma during fasting and euglycemic hyperinsulinemia.
Nuclear medicine and biology 2006;33(4):521-8.
2006: Marko S Laaksonen; Riikka Kivelä; Heikki Kyröläinen; Sarianna Sipilä; Harri Selänne; Riikka Lautamäki; Pirjo Nuutila; Juhani Knuuti; Kari K Kalliokoski; Paavo V Komi
Effects of exhaustive stretch-shortening cycle exercise on muscle blood flow during exercise.
Acta physiologica (Oxford, England) 2006;186(4):261-70.
2006: Jussi P Pärkkä; Pekka Niemi; Antti Saraste; Juha W Koskenvuo; Markku Komu; Vesa Oikonen; Jyri O Toikka; Tuomas O Kiviniemi; Juhani Knuuti; Hajime Sakuma; Jaakko Hartiala
Comparison of MRI and positron emission tomography for measuring myocardial perfusion reserve in healthy humans.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(4):772-9.
2006: Marko S Laaksonen; Heikki Kyröläinen; Kari K Kalliokoski; Pirjo Nuutila; Juhani Knuuti
The association between muscle EMG and perfusion in knee extensor muscles.
Clinical physiology and functional imaging 2006;26(2):99-105.
2006: Jan Sundell; Hanna Laine; Pirjo Nuutila; Matti Luotolahti; Juhani Knuuti
Short-term changes in inflammatory response protein (hsCRP) do not parallel with changes in coronary vasoreactivity in obese men.
International journal of obesity (2005) 2006;30(3):460-7.
2006: Reijo Laaksonen; Karin M Thelen; Hannu Päivä; Jussi Matinheikki; Risto Vesalainen; Tuula Janatuinen; Juhani Knuuti; Riikka Rontu; Klaus Von Bergmann; Dieter Lütjohann; Terho Lehtimäki
Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.
Atherosclerosis 2006;185(1):206-9.
2006: Riikka Kalliokoski; Ilkka Kantola; Kari K Kalliokoski; Erik Engblom; Jan Sundell; Jarna C Hannukainen; Tuula Janatuinen; Olli T Raitakari; Juhani Knuuti; Maila Penttinen; Jorma Viikari; Pirjo Nuutila
The effect of 12-month enzyme replacement therapy on myocardial perfusion in patients with Fabry disease.
Journal of inherited metabolic disease 2006;29(1):112-8.
2006: Riikka Lautamäki; K E Juhani Airaksinen; Marko Seppänen; Jyri O Toikka; Risto Härkönen; Matti Luotolahti; Ronald Borra; Jan Sundell; Juhani Knuuti; Pirjo Nuutila
Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease.
Diabetes 2006;55(2):511-6.
2006: Riikka Lautamäki; Pirjo Nuutila; K E Juhani Airaksinen; Aila Leino; Heikki Hiekkanen; Marian Turiceanu; Murray Stewart; Juhani Knuuti; Tapani Rönnemaa
The effect of PPARgamma-agonism on LDL subclass profile in patients with type 2 diabetes and coronary artery disease.
The review of diabetic studies : RDS 2006;3(1):31-8.
2006: Karin M Thelen; Dieter Lütjohann; Risto Vesalainen; Tuula Janatuinen; Juhani Knuuti; Klaus Von Bergmann; Terho Lehtimäki; Reijo Laaksonen
Effect of pravastatin on plasma sterols and oxysterols in men.
European journal of clinical pharmacology 2006;62(1):9-14.
2005: Jeroen J Bax; Theodore P Abraham; S Serge Barold; Ole-A. Breithardt; Jeffrey Wing-Hong Fung; Stephane Garrigue; John Gorcsan; David L Hayes; David A Kass; Juhani Knuuti; Christophe Leclercq; Cecilia Linde; Daniel B Mark; Mark J Monaghan; Petros Nihoyannopoulos; Martin J Schalij; Christophe Stellbrink; Cheuk-Man Yu
Cardiac resynchronization therapy: Part 2--issues during and after device implantation and unresolved questions.
Journal of the American College of Cardiology 2005;46(12):2168-82.
2005: Jeroen J Bax; Theodore P Abraham; S Serge Barold; Ole-A. Breithardt; Jeffrey Wing-Hong Fung; Stephane Garrigue; John Gorcsan; David L Hayes; David A Kass; Juhani Knuuti; Christophe Leclercq; Cecilia Linde; Daniel B Mark; Mark J Monaghan; Petros Nihoyannopoulos; Martin J Schalij; Christophe Stellbrink; Cheuk-Man Yu
Cardiac resynchronization therapy: Part 1--issues before device implantation.
Journal of the American College of Cardiology 2005;46(12):2153-67.
2005: Markku Vänttinen; Pirjo Nuutila; Tiina Kuulasmaa; Jussi Pihlajamäki; Kirsti Hällsten; Kirsi A Virtanen; Riikka Lautamäki; Pauliina Peltoniemi; Teemu Takala; Antti Viljanen; Juhani Knuuti; Markku Laakso
Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene are associated with skeletal muscle glucose uptake.
Diabetes 2005;54(12):3587-91.
2005: Alexandru Naum; Marko S Laaksonen; Helena Tuunanen; Vesa Oikonen; Mika Teräs; Jukka Kemppainen; Mikko J Järvisalo; Pirjo Nuutila; Juhani Knuuti
Motion detection and correction for dynamic ( 15)O-water myocardial perfusion PET studies.
European journal of nuclear medicine and molecular imaging 2005;32(12):1378-83.
2005: Teemu Kalliokoski; Olli Simell; Merja Haaparanta; Tapio Viljanen; Olof Solin; Juhani Knuuti; Pirjo Nuutila
An autoradiographic study of [(18)F]FDG uptake to islets of Langerhans in NOD mouse.
Diabetes research and clinical practice 2005;70(3):217-24.
2005: Jarna C Hannukainen; Kari K Kalliokoski; Pirjo Nuutila; T Fujimoto; Jukka Kemppainen; Tapio Viljanen; Marko S Laaksonen; Riitta Parkkola; Juhani Knuuti; Michael Kjaer
In vivo measurements of glucose uptake in human Achilles tendon during different exercise intensities.
International journal of sports medicine 2005;26(9):727-31.
2005: Jukka Kemppainen; Sargo Aalto; Toshihiko Fujimoto; Kari K Kalliokoski; Jaakko W Långsjö; Vesa Oikonen; Juha Rinne; Pirjo Nuutila; Juhani Knuuti
High intensity exercise decreases global brain glucose uptake in humans.
The Journal of physiology 2005;568(Pt 1):323-32.
2005: Riikka Lautamäki; K E Juhani Airaksinen; Marko Seppänen; Jyri O Toikka; Matti Luotolahti; Elizabeth Ball; Ronald Borra; Risto Härkönen; Patricia Iozzo; Murray Stewart; Juhani Knuuti; Pirjo Nuutila
Rosiglitazone improves myocardial glucose uptake in patients with type 2 diabetes and coronary artery disease: a 16-week randomized, double-blind, placebo-controlled study.
Diabetes 2005;54(9):2787-94.
2005: Kirsi A Virtanen; Patricia Iozzo; Kirsti Hällsten; Risto Huupponen; Riitta Parkkola; Tuula Janatuinen; Fredrik Lönnqvist; Tapio Viljanen; Tapani Rönnemaa; Peter Lönnroth; Juhani Knuuti; Ele Ferrannini; Pirjo Nuutila
Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study.
Diabetes 2005;54(9):2720-6.
2005: Birger Hesse; Kristina Tägil; Alberto Cuocolo; Constantinos Anagnostopoulos; M Bardiés; J Bax; Frank M Bengel; E Busemann Sokole; Glyn Davies; M Dondi; Lars Edenbrandt; P Franken; Andreas Kjaer; Juhani Knuuti; M Lassmann; M Ljungberg; C Marcassa; P Y Marie; F McKiddie; M O'Connor; Elizabeth Prvulovich; R Underwood; Berthe L F van Eck-Smit
EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology.
European journal of nuclear medicine and molecular imaging 2005;32(7):855-97.
2005: Markku Vänttinen; Pirjo Nuutila; Jussi Pihlajamäki; Kirsti Hällsten; Kirsi A Virtanen; Riikka Lautamäki; Pauliina Peltoniemi; Jukka Kemppainen; Teemu Takala; Antti Viljanen; Juhani Knuuti; Markku Laakso
The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study.
The Journal of clinical endocrinology and metabolism 2005;90(7):4249-54.
2005: Jyri K Koort; Tatu J Mäkinen; Esa Suokas; Minna Veiranto; Jari Jalava; Juhani Knuuti; Pertti Törmälä; Hannu T Aro
Efficacy of ciprofloxacin-releasing bioabsorbable osteoconductive bone defect filler for treatment of experimental osteomyelitis due to Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2005;49(4):1502-8.
2005: Jan Sundell; Hanna Laine; Olli T Raitakari; Matti Luotolahti; Pirjo Nuutila; Jorma Viikari; Juhani Knuuti
Increased lipoprotein(a) is associated with reduced myocardial vasoreactivity in young healthy men.
Atherosclerosis 2005;179(1):185-91.
2005: Tatu J Mäkinen; Minna Veiranto; Juhani Knuuti; Jari Jalava; Pertti Törmälä; Hannu T Aro
Efficacy of bioabsorbable antibiotic containing bone screw in the prevention of biomaterial-related infection due to Staphylococcus aureus.
Bone 2005;36(2):292-9.
2005: Riikka Kalliokoski; Kari K Kalliokoski; Jan Sundell; Erik Engblom; Maila Penttinen; Ilkka Kantola; Olli T Raitakari; Juhani Knuuti; Pirjo Nuutila
Impaired myocardial perfusion reserve but preserved peripheral endothelial function in patients with Fabry disease.
Journal of inherited metabolic disease 2005;28(4):563-73.
2005: Jan Sundell; Tuula Janatuinen; Tapani Rönnemaa; Alexandru Naum; Hanna Laine; Matti Luotolahti; Pirjo Nuutila; Olli T Raitakari; Juhani Knuuti
Lifetime glycaemic exposure predicts reduced coronary vasoreactivity in Type 1 diabetic subjects.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(1):45-51.
2005: Kari K Kalliokoski; Juhani Knuuti; Pirjo Nuutila
Relationship between muscle blood flow and oxygen uptake during exercise in endurance-trained and untrained men.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;98(1):380-3.
2004: Eero I T Sihvo; Jari V Räsänen; Juhani Knuuti; Heikki Minn; Markku E S Luostarinen; Tapio Viljanen; Markus Färkkilä; Jarmo A Salo
Adenocarcinoma of the esophagus and the esophagogastric junction: positron emission tomography improves staging and prediction of survival in distant but not in locoregional disease.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004;8(8):988-96.
2004: Kirsti Hällsten; Kirsi A Virtanen; Fredrik Lönnqvist; Tuula Janatuinen; M Turiceanu; Tapani Rönnemaa; Jorma Viikari; T Lehtimäki; Juhani Knuuti; Pirjo Nuutila
Enhancement of insulin-stimulated myocardial glucose uptake in patients with Type 2 diabetes treated with rosiglitazone.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(12):1280-7.
2004: Tarja A Kunnas; Terho Lehtimäki; Pekka J Karhunen; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Seppo T Nikkari
Estrogen receptor genotype modulates myocardial perfusion in young men.
Journal of molecular medicine (Berlin, Germany) 2004;82(12):821-5.
2004: Juhani Knuuti; Jan Sundell; Alexandru Naum; Erik Engblom; Juhani Koistinen; Antti Ylitalo; Kira Q Stolen; Riikka Kalliokoski; Stephan Nekolla; K E Jeroen J Bax; K E Juhani Airaksinen
Assessment of right ventricular oxidative metabolism by PET in patients with idiopathic dilated cardiomyopathy undergoing cardiac resynchronization therapy.
European journal of nuclear medicine and molecular imaging 2004;31(12):1592-8.
2004: Jan Sundell; Tapani Rönnemaa; Hanna Laine; Olli T Raitakari; Matti Luotolahti; Pirjo Nuutila; Juhani Knuuti
High-sensitivity C-reactive protein and impaired coronary vasoreactivity in young men with uncomplicated type 1 diabetes.
Diabetologia 2004;47(11):1888-94.
2004: Janne Aittoniemi; Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Janne Hulkkonen; Mikko Hurme; Terho Lehtimäki
The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men.
International journal of cardiology 2004;97(2):317-8.
2004: Patricia Iozzo; Teemu Takala; Vesa Oikonen; Jörgen Bergman; Tove Grönroos; Ele Ferrannini; Pirjo Nuutila; Juhani Knuuti
Effect of training status on regional disposal of circulating free fatty acids in the liver and skeletal muscle during physiological hyperinsulinemia.
Diabetes care 2004;27(9):2172-7.
2004: Jyri K Koort; Tatu J Mäkinen; Juhani Knuuti; Jari Jalava; Hannu T Aro
Comparative 18F-FDG PET of experimental Staphylococcus aureus osteomyelitis and normal bone healing.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(8):1406-11.
2004: Kari K Kalliokoski; Marko S Laaksonen; Matti Luotolahti; Hanna Laine; Teemu Takala; Pirjo Nuutila; Juhani Knuuti
Myocardial perfusion after marathon running.
Scandinavian journal of medicine & science in sports 2004;14(4):208-14.
2004: Patricia Iozzo; R Lautamaki; F Geisler; Kirsi A Virtanen; Vesa Oikonen; Merja Haaparanta; H Yki-Jarvinen; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Non-esterified fatty acids impair insulin-mediated glucose uptake and disposition in the liver.
Diabetologia 2004;47(7):1149-56.
2004: Patricia Iozzo; Anu K Turpeinen; Teemu Takala; Vesa Oikonen; Jörgen Bergman; Tove Grönroos; Ele Ferrannini; Pirjo Nuutila; Juhani Knuuti
Defective liver disposal of free fatty acids in patients with impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 2004;89(7):3496-502.
2004: Tuula Janatuinen; Juhani Knuuti; Jyri O Toikka; Markku Ahotupa; Pirjo Nuutila; Tapani Rönnemaa; Olli T Raitakari
Effect of pravastatin on low-density lipoprotein oxidation and myocardial perfusion in young adults with type 1 diabetes.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1303-8.
2004: S Richard Underwood; Jeroen J Bax; Jürgen vom Dahl; Michael Y Henein; Juhani Knuuti; Albert C van Rossum; Ernst R Schwarz; Jean-Louis J Vanoverschelde; Ernst E van der Wall; William Wijns
Imaging techniques for the assessment of myocardial hibernation. Report of a Study Group of the European Society of Cardiology.
European heart journal 2004;25(10):815-36.
2004: Jan Sundell; Tuula Janatuinen; Tapani Rönnemaa; Olli T Raitakari; Jyri O Toikka; Pirjo Nuutila; Juhani Knuuti
Diabetic background retinopathy is associated with impaired coronary vasoreactivity in people with Type 1 diabetes.
Diabetologia 2004;47(4):725-31.
2004: Kira Q Stolen; Jukka Kemppainen; Kari K Kalliokoski; Kirsti Hällsten; Matti Luotolahti; Hannu Karanko; Pertti Lehikoinen; Tapio Viljanen; Tiina Salo; K E Juhani Airaksinen; Pirjo Nuutila; Juhani Knuuti
Myocardial perfusion reserve and oxidative metabolism contribute to exercise capacity in patients with dilated cardiomyopathy.
Journal of cardiac failure 2004;10(2):132-40.
2004: Juhani Knuuti
Clinical cardiac PET in the future.
European journal of nuclear medicine and molecular imaging 2004;31(4):467-8.
2004: Jan Sundell; Erik Engblom; Juhani Koistinen; Antti Ylitalo; Alexandru Naum; Kira Q Stolen; Riikka Kalliokoski; Stephan Nekolla; K E Juhani Airaksinen; Jeroen J Bax; Juhani Knuuti
The effects of cardiac resynchronization therapy on left ventricular function, myocardial energetics, and metabolic reserve in patients with dilated cardiomyopathy and heart failure.
Journal of the American College of Cardiology 2004;43(6):1027-33.
2004: Arja Muhonen; Merja Haaparanta; Tove Grönroos; J Bergman; Juhani Knuuti; Susanna Hinkka; Risto-Pekka Happonen
Osteoblastic activity and neoangiogenesis in distracted bone of irradiated rabbit mandible with or without hyperbaric oxygen treatment.
International journal of oral and maxillofacial surgery 2004;33(2):173-8.
2004: Kari K Kalliokoski; Juhani Knuuti; Pirjo Nuutila
Blood transit time heterogeneity is associated to oxygen extraction in exercising human skeletal muscle.
Microvascular research 2004;67(2):125-32.
2004: Hanna Laine; Jan Sundell; P Nuutila; Olli T Raitakari; Matti Luotolahti; T Rönnemaa; T Elomaa; P Koskinen; Juhani Knuuti
Insulin induced increase in coronary flow reserve is abolished by dexamethasone in young men with uncomplicated type 1 diabetes.
Heart (British Cardiac Society) 2004;90(3):270-6.
2004: Riikka Mäkelä; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Olli Jaakkola; Juhani Knuuti; Terho Lehtimäki
Myeloperoxidase gene variation and coronary flow reserve in young healthy men.
Journal of biomedical science 2004;11(1):59-64.
2004: Kira Q Stolen; Jukka Kemppainen; Kari K Kalliokoski; Hannu Karanko; Jyri O Toikka; Tuula Janatuinen; Olli T Raitakari; K E Juhani Airaksinen; Pirjo Nuutila; Juhani Knuuti
Myocardial perfusion reserve and peripheral endothelial function in patients with idiopathic dilated cardiomyopathy.
The American journal of cardiology 2004;93(1):64-8.
2004: Angelika Bischof Delaloye; Liselotte Højgaard; Juhani Knuuti
Peter Ell: portrait of an editor.
European journal of nuclear medicine and molecular imaging 2004;31(1):3-4.
2004: Bo-Lennart Johansson; Jan Sundell; Karin Ekberg; Cathrine Jonsson; Marko Seppänen; Olli T Raitakari; Matti Luotolahti; Pirjo Nuutila; John Wahren; Juhani Knuuti
C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients.
American journal of physiology. Endocrinology and metabolism 2004;286(1):E14-9.
2003: Allan J Aho; Erkki Suominen; Anu Alanen; Antti Yli-Urpo; Juhani Knuuti; Heikki J Aho
Remodeling of the tibia after grafting of a large cavity with particulate bioactive glass-hydroxylapatite--case report on treatment of fibrous dysplasia with 13 years' follow-up.
Acta orthopaedica Scandinavica 2003;74(6):766-70.
2003: Jari V Räsänen; Eero I T Sihvo; Juhani Knuuti; Heikki Minn; Markku E S Luostarinen; Pekka Laippala; Tapio Viljanen; Jarmo A Salo
Prospective analysis of accuracy of positron emission tomography, computed tomography, and endoscopic ultrasonography in staging of adenocarcinoma of the esophagus and the esophagogastric junction.
Annals of surgical oncology 2003;10(8):954-60.
2003: Terho Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Kari Mattila; Erkki Ilveskoski; Mari Luomala; Pekka Saikku; Juhani Knuuti; Mikko Hurme
Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.
Pharmacogenetics 2003;13(10):633-9.
2003: Heinrich R Schelbert; Rob S B Beanlands; Frank M Bengel; Juhani Knuuti; Marcelo F Dicarli; Josef Machac; Randolph Patterson
PET myocardial perfusion and glucose metabolism imaging: Part 2-Guidelines for interpretation and reporting.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2003;10(5):557-71.
2003: Kira Q Stolen; Jukka Kemppainen; Kari K Kalliokoski; Matti Luotolahti; Tapio Viljanen; Pirjo Nuutila; Juhani Knuuti
Exercise training improves insulin-stimulated myocardial glucose uptake in patients with dilated cardiomyopathy.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2003;10(5):447-55.
2003: Timo Mäkelä; Quoc Cuong Pham; Patrick CLARYSSE; Jukka Nenonen; Jyrki Lötjönen; Outi Sipilä; Helena Hänninen; Kirsi Lauerma; Juhani Knuuti; Toivo Katila; Isabelle E Magnin
A 3-D model-based registration approach for the PET, MR and MCG cardiac data fusion.
Medical image analysis 2003;7(3):377-89.
2003: Jukka Kemppainen; Kira Q Stolen; Kari K Kalliokoski; Tiina Salo; Hannu Karanko; Tapio Viljanen; Juhani Airaksinen; Pirjo Nuutila; Juhani Knuuti
Exercise training improves insulin stimulated skeletal muscle glucose uptake independent of changes in perfusion in patients with dilated cardiomyopathy.
Journal of cardiac failure 2003;9(4):286-95.
2003: Kari K Kalliokoski; Marko S Laaksonen; Juhani Knuuti; Pirjo Nuutila
Perfusion distribution between and within muscles during intermittent static exercise in endurance-trained and untrained men.
International journal of sports medicine 2003;24(6):400-3.
2003: Patricia Iozzo; Anu K Turpeinen; Teemu Takala; Vesa Oikonen; Olof Solin; Ele Ferrannini; Pirjo Nuutila; Juhani Knuuti
Liver uptake of free fatty acids in vivo in humans as determined with 14( R, S)-[18F]fluoro-6-thia-heptadecanoic acid and PET.
European journal of nuclear medicine and molecular imaging 2003;30(8):1160-4.
2003: Patricia Iozzo; Kirsti Hallsten; Vesa Oikonen; Kirsi A Virtanen; Riitta Parkkola; Jukka Kemppainen; Olof Solin; Fredrik Lonnqvist; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Effects of metformin and rosiglitazone monotherapy on insulin-mediated hepatic glucose uptake and their relation to visceral fat in type 2 diabetes.
Diabetes care 2003;26(7):2069-74.
2003: Jukka Kemppainen; Håkan Karlsson; Kira Q Stolen; Håkan Karlsson; Marie Björnholm; Olli Heinonen; Pirjo Nuutila; Anna Krook; Juhani Knuuti; Juleen R Zierath
Insulin signalling and resistance in patients with chronic heart failure.
The Journal of physiology 2003;550(Pt 1):305-15.
2003: Jan Sundell; Risto Huupponen; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti
High serum leptin is associated with attenuated coronary vasoreactivity.
Obesity research 2003;11(6):776-82.
2003: Toshihiko Fujimoto; Jukka Kemppainen; Kari K Kalliokoski; Pirjo Nuutila; Masatoshi Ito; Juhani Knuuti
Skeletal muscle glucose uptake response to exercise in trained and untrained men.
Medicine and science in sports and exercise 2003;35(5):777-83.
2003: Patricia Iozzo; Fabian Geisler; Vesa Oikonen; Maija Mäki; Teemu Takala; Olof Solin; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Insulin stimulates liver glucose uptake in humans: an 18F-FDG PET Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(5):682-9.
2003: Patricia Iozzo; Kirsti Hallsten; Vesa Oikonen; Kirsi A Virtanen; Jukka Kemppainen; Olof Solin; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Insulin-mediated hepatic glucose uptake is impaired in type 2 diabetes: evidence for a relationship with glycemic control.
The Journal of clinical endocrinology and metabolism 2003;88(5):2055-60.
2003: Marko S Laaksonen; Kari K Kalliokoski; Heikki Kyröläinen; Jukka Kemppainen; Mika Teräs; Hannu Sipilä; Pirjo Nuutila; Juhani Knuuti
Skeletal muscle blood flow and flow heterogeneity during dynamic and isometric exercise in humans.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H979-86.
2003: Kari K Kalliokoski; Marko S Laaksonen; Teemu Takala; Juhani Knuuti; Pirjo Nuutila
Muscle oxygen extraction and perfusion heterogeneity during continuous and intermittent static exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;94(3):953-8.
2003: Kira Q Stolen; Jukka Kemppainen; Heikki Ukkonen; Kari K Kalliokoski; Matti Luotolahti; Pertti Lehikoinen; Helena Hämäläinen; Tiina Salo; K E Juhani Airaksinen; Pirjo Nuutila; Juhani Knuuti
Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopathy.
Journal of the American College of Cardiology 2003;41(3):460-7.
2003: Kirsti Hällsten; Hannele Yki-Järvinen; Pauliina Peltoniemi; Vesa Oikonen; Teemu Takala; Jukka Kemppainen; Hanna Laine; Jörgen Bergman; Geremia B Bolli; Juhani Knuuti; Pirjo Nuutila
Insulin- and exercise-stimulated skeletal muscle blood flow and glucose uptake in obese men.
Obesity research 2003;11(2):257-65.
2003: Jan Sundell; Juhani Knuuti
Insulin and myocardial blood flow.
Cardiovascular research 2003;57(2):312-9.
2003: Kirsi A Virtanen; Kirsti Hällsten; Riitta Parkkola; Tuula Janatuinen; Fredrik Lönnqvist; Tapio Viljanen; Tapani Rönnemaa; Juhani Knuuti; Risto Huupponen; Peter Lönnroth; Pirjo Nuutila
Differential effects of rosiglitazone and metformin on adipose tissue distribution and glucose uptake in type 2 diabetic subjects.
Diabetes 2003;52(2):283-90.
2003: Kari K Kalliokoski; Tom A Kuusela; Marko S Laaksonen; Juhani Knuuti; Pirjo Nuutila
Muscle fractal vascular branching pattern and microvascular perfusion heterogeneity in endurance-trained and untrained men.
The Journal of physiology 2003;546(Pt 2):529-35.
2003: Tuula Janatuinen; Juha Laakso; Reijo Laaksonen; Risto Vesalainen; Pirjo Nuutila; Terho Lehtimäki; Olli T Raitakari; Juhani Knuuti
Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults.
Vascular medicine (London, England) 2003;8(3):185-9.
2003: Juha W Koskenvuo; Markku Saraste; Pekka Niemi; Juhani Knuuti; Hajime Sakuma; Jyri O Toikka; Markku Komu; Mikko J Järvisalo; Jaakko Hartiala
Correlation of transthoracic Doppler echocardiography and magnetic resonance imaging in measuring left anterior descending artery flow velocity and time-course of dipyridamole-induced coronary flow increase.
Scandinavian journal of clinical and laboratory investigation 2003;63(1):65-72.
2003: Jan Sundell; Hanna Laine; Matti Luotolahti; Pirjo Nuutila; Kari K Kalliokoski; Olli T Raitakari; Juhani Knuuti
Blunted coronary vasoreactivity to insulin is an early alteration in hypertension.
Journal of vascular research 2003;40(1):58-67.
2002: Tarja A Kunnas; Terho Lehtimäki; Reijo Laaksonen; Erkki Ilveskoski; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Pekka J Karhunen; Juhani Knuuti; Seppo T Nikkari
Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study.
Journal of molecular medicine (Berlin, Germany) 2002;80(12):802-7.
2002: Teemu O Takala; Pirjo Nuutila; Kari Pulkki; Vesa Oikonen; Tove Grönroos; Timo Savunen; Tommi Vähäsilta; Matti Luotolahti; Markku Kallajoki; Jörgen Bergman; Sarita Forsback; Juhani Knuuti
14(R,S)-[18F]Fluoro-6-thia-heptadecanoic acid as a tracer of free fatty acid uptake and oxidation in myocardium and skeletal muscle.
European journal of nuclear medicine and molecular imaging 2002;29(12):1617-22.
2002: Kirsti Hällsten; Kirsi A Virtanen; Fredrik Lönnqvist; Hannu Sipilä; Airi Oksanen; Tapio Viljanen; Tapani Rönnemaa; Jorma Viikari; Juhani Knuuti; Pirjo Nuutila
Rosiglitazone but not metformin enhances insulin- and exercise-stimulated skeletal muscle glucose uptake in patients with newly diagnosed type 2 diabetes.
Diabetes 2002;51(12):3479-85.
2002: Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Terho Lehtimäki; Irina Elovaara; Olli Jaakkola; Hannu Jokela; Juha Laakso; Pirjo Nuutila; K Punnonen; Olli T Raitakari; P Saikku; Kimmo Salminen; Juhani Knuuti
High oxidized LDL and elevated plasma homocysteine contribute to the early reduction of myocardial flow reserve in healthy adults.
European journal of clinical investigation 2002;32(11):795-802.
2002: Markku R Asola; Kirsi A Virtanen; Pauliina Peltoniemi; Kjell Någren; Meixiang Yu; Kari Mattila; Sirkku Jyrkkiö; Kaj Metsärinne; Pirjo Nuutila; Juhani Knuuti
Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET.
European journal of nuclear medicine and molecular imaging 2002;29(11):1485-91.
2002: Hannu Päivä; Juha Laakso; Hanna Laine; Reijo Laaksonen; Juhani Knuuti; Olli T Raitakari
Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia.
Journal of the American College of Cardiology 2002;40(7):1241-7.
2002: Arja Muhonen; Jarkko Muhonen; Heikki Minn; Jarmo Kulmala; Jorma Klossner; Mika Teräs; Juhani Knuuti; Risto-Pekka Happonen
The effects of irradiation and hyperbaric oxygen on bone formation during rabbit mandibular distraction.
Archives of oral biology 2002;47(10):701-7.
2002: Jan Sundell; Hanna Laine; Matti Luotolahti; Pirjo Nuutila; Juhani Knuuti
Increased coronary vascular resistance cannot be reduced by inhibiting sympathetic overactivity in hypertension.
Journal of vascular research 2002;39(5):456-62.
2002: Juhani Knuuti; Heinrich R Schelbert; Jeroen J Bax
The need for standardisation of cardiac FDG PET imaging in the evaluation of myocardial viability in patients with chronic ischaemic left ventricular dysfunction.
European journal of nuclear medicine and molecular imaging 2002;29(9):1257-66.
2002: Kirsi A Virtanen; Peter Lönnroth; Riitta Parkkola; Pauliina Peltoniemi; Markku R Asola; Tapio Viljanen; Tuula Tolvanen; Juhani Knuuti; Tapani Rönnemaa; Risto Huupponen; Pirjo Nuutila
Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans.
The Journal of clinical endocrinology and metabolism 2002;87(8):3902-10.
2002: Jukka Kemppainen; Toshihiko Fujimoto; Kari K Kalliokoski; Tapio Viljanen; Pirjo Nuutila; Juhani Knuuti
Myocardial and skeletal muscle glucose uptake during exercise in humans.
The Journal of physiology 2002;542(Pt 2):403-12.
2002: Jan Sundell; Hanna Laine; Matti Luotolahti; Kari K Kalliokoski; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti
Obesity affects myocardial vasoreactivity and coronary flow response to insulin.
Obesity research 2002;10(7):617-24.
2002: Jan Sundell; Hanna Laine; Pirjo Nuutila; Tapani Rönnemaa; Matti Luotolahti; Olli T Raitakari; Juhani Knuuti
The effects of insulin and short-term hyperglycaemia on myocardial blood flow in young men with uncomplicated Type I diabetes.
Diabetologia 2002;45(6):775-82.
2002: Terho Lehtimäki; Reijo Laaksonen; Kari M Mattila; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juha Laakso; Olli Jaakkola; Timo Koivula; Juhani Knuuti
Oestrogen receptor gene variation is a determinant of coronary reactivity in healthy young men.
European journal of clinical investigation 2002;32(6):400-4.
2002: Kari K Kalliokoski; Pirjo Nuutila; Hanna Laine; Matti Luotolahti; Tuula Janatuinen; Olli T Raitakari; Teemu O Takala; Juhani Knuuti
Myocardial perfusion and perfusion reserve in endurance-trained men.
Medicine and science in sports and exercise 2002;34(6):948-53.
2002: Arja Muhonen; Timo Peltomäki; Juhani Knuuti; Olli T Raitakari; Risto-Pekka Happonen
Osteoblastic activity of the rabbit temporomandibular joint during distraction osteogenesis assessed by [18F]fluoride positron emission tomography.
European journal of oral sciences 2002;110(2):144-8.
2002: Jan Sundell; Pirjo Nuutila; Hanna Laine; Matti Luotolahti; Kari K Kalliokoski; Olli T Raitakari; Juhani Knuuti
Dose-dependent vasodilating effects of insulin on adenosine-stimulated myocardial blood flow.
Diabetes 2002;51(4):1125-30.
2002: Tuula Janatuinen; Johan Friberg; Matti K Viljanen; Olli T Raitakari; Pirjo Nuutila; Raija Vainionpää; Jarmo Oksi; Reijo Peltonen; Erik Engblom; Hanna Laine; Juhani Knuuti
Early impairment of coronary flow reserve is not associated with Chlamydia pneumoniae antibodies.
Annals of medicine 2002;34(4):284-90.
2001: Kirsi A Virtanen; Pauliina Peltoniemi; Päivi Marjamäki; Markku R Asola; Lena Strindberg; Riitta Parkkola; Risto Huupponen; Juhani Knuuti; Peter Lönnroth; Pirjo Nuutila
Human adipose tissue glucose uptake determined using [(18)F]-fluoro-deoxy-glucose ([(18)F]FDG) and PET in combination with microdialysis.
Diabetologia 2001;44(12):2171-9.
2001: Pauliina Peltoniemi; Hannele Yki-Järvinen; Hanna Laine; Vesa Oikonen; Tapani Rönnemaa; Kari K Kalliokoski; Olli T Raitakari; Juhani Knuuti; Pirjo Nuutila
Evidence for spatial heterogeneity in insulin- and exercise-induced increases in glucose uptake: studies in normal subjects and patients with type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2001;86(11):5525-33.
2001: Juha W Koskenvuo; Jaakko Hartiala; Juhani Knuuti; Hajime Sakuma; Jyri O Toikka; Markku Komu; Markku Saraste; Pekka Niemi
Assessing coronary sinus blood flow in patients with coronary artery disease: a comparison of phase-contrast MR imaging with positron emission tomography.
AJR. American journal of roentgenology 2001;177(5):1161-6.
2001: Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Terho Lehtimäki
Effects of pravastatin therapy on serum lipids and coronary reactivity are not associated with SREBP cleavage-activating protein polymorphism in healthy young men.
Clinical genetics 2001;60(4):319-21.
2001: R Malin; Reijo Laaksonen; Juhani Knuuti; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Terho Lehtimäki
Paraoxonase genotype modifies the effect of pravastatin on high-density lipoprotein cholesterol.
Pharmacogenetics 2001;11(7):625-33.
2001: Tuula Janatuinen; Reijo Laaksonen; Risto Vesalainen; Olli T Raitakari; Terho Lehtimäki; Pirjo Nuutila; Juhani Knuuti
Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults.
Journal of cardiovascular pharmacology 2001;38(4):561-8.
2001: Bernhard L Gerber; F F Ordoubadi; W Wijns; J L Vanoverschelde; Juhani Knuuti; M Janier; P Melon; P K Blanksma; Anne Bol; J J Bax; Jacques A Melin; P G Camici
Positron emission tomography using(18)F-fluoro-deoxyglucose and euglycaemic hyperinsulinaemic glucose clamp: optimal criteria for the prediction of recovery of post-ischaemic left ventricular dysfunction. Results from the European Community Concerted Action Multicenter study on use of(18)F-fluoro-deoxyglucose Positron Emission Tomography for the Detection of Myocardial Viability.
European heart journal 2001;22(18):1691-701.
2001: Alessandra Bertoldo; Pauliina Peltoniemi; Vesa Oikonen; Juhani Knuuti; Pirjo Nuutila; Claudio Cobelli
Kinetic modeling of [(18)F]FDG in skeletal muscle by PET: a four-compartment five-rate-constant model.
American journal of physiology. Endocrinology and metabolism 2001;281(3):E524-36.
2001: R Malin; Juhani Knuuti; Tuula Janatuinen; Reijo Laaksonen; Risto Vesalainen; Pirjo Nuutila; Hannu Jokela; J Laakso; Olli Jaakkola; Tiina Solakivi; Terho Lehtimäki
Paraoxonase gene polymorphisms and coronary reactivity in young healthy men.
Journal of molecular medicine (Berlin, Germany) 2001;79(8):449-58.
2001: Anne Kalela; Reijo Laaksonen; Terho Lehtimäki; Tommi A Koivu; Matti Höyhtyä; Tuula Janatuinen; Perttu J Pöllänen; Risto Vesalainen; P Saikku; Juhani Knuuti; Seppo T Nikkari
Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases.
The American journal of cardiology 2001;88(2):173-5, A6.
2001: Olli T Raitakari; Jyri O Toikka; Hanna Laine; Markku Ahotupa; H Iida; Jorma S A Viikari; Jaakko Hartiala; Juhani Knuuti
Reduced myocardial flow reserve relates to increased carotid intima-media thickness in healthy young men.
Atherosclerosis 2001;156(2):469-75.
2001: Pauliina Peltoniemi; Hannele Yki-Järvinen; Vesa Oikonen; Airi Oksanen; Teemu Takala; Tapani Rönnemaa; M Erkinjuntti; Juhani Knuuti; Pirjo Nuutila
Resistance to exercise-induced increase in glucose uptake during hyperinsulinemia in insulin-resistant skeletal muscle of patients with type 1 diabetes.
Diabetes 2001;50(6):1371-7.
2001: Kari K Kalliokoski; Vesa Oikonen; Teemu Takala; Hannu Sipilä; Juhani Knuuti; Pirjo Nuutila
Enhanced oxygen extraction and reduced flow heterogeneity in exercising muscle in endurance-trained men.
American journal of physiology. Endocrinology and metabolism 2001;280(6):E1015-21.
2001: Kari K Kalliokoski; Tom A Kuusela; Pirjo Nuutila; Tuula Tolvanen; Vesa Oikonen; Mika Teräs; T E Takala; Juhani Knuuti
Perfusion heterogeneity in human skeletal muscle: fractal analysis of PET data.
European journal of nuclear medicine 2001;28(4):450-6.
2001: Heikki Ukkonen; Juhani Knuuti; C Katoh; H Iida; Hannu Sipilä; Pertti Lehikoinen; Kjell Någren; Liisa-Maria Voipio-Pulkki
Use of [11C]acetate and [15O]O2 PET for the assessment of myocardial oxygen utilization in patients with chronic myocardial infarction.
European journal of nuclear medicine 2001;28(3):334-9.
2001: Juha W Koskenvuo; Hajime Sakuma; Pekka Niemi; Jyri O Toikka; Juhani Knuuti; Hanna Laine; Markku Komu; Martti Kormano; Markku Saraste; Jaakko Hartiala
Global myocardial blood flow and global flow reserve measurements by MRI and PET are comparable.
Journal of magnetic resonance imaging : JMRI 2001;13(3):361-6.
2001: Juhani Knuuti; Teemu Takala; Kjell Någren; Hannu Sipilä; Anu K Turpeinen; M I J Uusitupa; Pirjo Nuutila
Myocardial fatty acid oxidation in patients with impaired glucose tolerance.
Diabetologia 2001;44(2):184-7.
2001: Jukka Nenonen; Katja Pesola; Helena Hänninen; Kirsi Lauerma; Panu Takala; Timo Mäkelä; Markku Makijarvi; Juhani Knuuti; Lauri Toivonen; Toivo Katila
Current-density estimation of exercise-induced ischemia in patients with multivessel coronary artery disease.
Journal of electrocardiology 2001;34 Suppl():37-42.
2001: Markku Saraste; Juha W Koskenvuo; Juhani Knuuti; Jyri O Toikka; Hanna Laine; Pekka Niemi; Hajime Sakuma; Jaakko Hartiala
Coronary flow reserve: measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography.
Clinical physiology (Oxford, England) 2001;21(1):114-22.
2000: Kirsi Lauerma; P Niemi; Helena Hänninen; T Janatuinen; Liisa-Maria Voipio-Pulkki; Juhani Knuuti; Lauri Toivonen; Timo Mäkelä; Markku Makijarvi; Hannu J Aronen
Multimodality MR imaging assessment of myocardial viability: combination of first-pass and late contrast enhancement to wall motion dynamics and comparison with FDG PET-initial experience.
Radiology 2000;217(3):729-36.
2000: Kari K Kalliokoski; Jukka Kemppainen; K Larmola; Teemu Takala; Pauliina Peltoniemi; Airi Oksanen; Ulla Ruotsalainen; C Cobelli; Juhani Knuuti; Pirjo Nuutila
Muscle blood flow and flow heterogeneity during exercise studied with positron emission tomography in humans.
European journal of applied physiology 2000;83(4 -5):395-401.
2000: Heikki Ukkonen; Markku Saraste; Juha Akkila; Juhani Knuuti; M Karanko; H Iida; Pertti Lehikoinen; Kjell Någren; Lasse Lehtonen; Liisa-Maria Voipio-Pulkki
Myocardial efficiency during levosimendan infusion in congestive heart failure.
Clinical pharmacology and therapeutics 2000;68(5):522-31.
2000: Pauliina Peltoniemi; Peter Lönnroth; Hanna Laine; Vesa Oikonen; Tuula Tolvanen; Tove Grönroos; Lena Strindberg; Juhani Knuuti; Pirjo Nuutila
Lumped constant for [(18)F]fluorodeoxyglucose in skeletal muscles of obese and nonobese humans.
American journal of physiology. Endocrinology and metabolism 2000;279(5):E1122-30.
2000: Hajime Sakuma; Juha W Koskenvuo; Pekka Niemi; N Kawada; Jyri O Toikka; Juhani Knuuti; Hanna Laine; Markku Saraste; Martti Kormano; Jaakko Hartiala
Assessment of coronary flow reserve using fast velocity-encoded cine MR imaging: validation study using positron emission tomography.
AJR. American journal of roentgenology 2000;175(4):1029-33.
2000: K A Bergström; R Härkönen; Kalevi Kairemo; Sirkka-Liisa Karonen; Juhani Knuuti; Jyrki T Kuikka; B A Lamberg; Esko Länsimies; K Liewendahl; Paivi Nikkinen; A Rekonen; S Savolainen; Esko Vanninen; E Vauramo; U Wegelius
The development of nuclear medicine in Finland: a review on the occasion of the 40th anniversary of the Finnish Society of Nuclear Medicine.
Clinical physiology (Oxford, England) 2000;20(5):317-29.
1999: O P Pitkanen; Hanna Laine; Jukka Kemppainen; E Eronen; Anna Alanen; Maria Raitakari; O Kirvela; Ulla Ruotsalainen; Juhani Knuuti; V A Koivisto; Pirjo Nuutila
Sodium nitroprusside increases human skeletal muscle blood flow, but does not change flow distribution or glucose uptake.
The Journal of physiology 1999;521 Pt 3():729-37.
1999: Hanna Laine; C Katoh; Matti Luotolahti; Hannele Yki-Järvinen; Ilkka Kantola; Antti Jula; Teemu Takala; Ulla Ruotsalainen; H Iida; Merja Haaparanta; Pirjo Nuutila; Juhani Knuuti
Myocardial oxygen consumption is unchanged but efficiency is reduced in patients with essential hypertension and left ventricular hypertrophy.
Circulation 1999;100(24):2425-30.
1999: Juhani Knuuti; Pirjo Nuutila
PET as a cardiovascular and metabolic research tool.
Annals of medicine 1999;31(6):450-6.
1999: H Scheinin; Mika Scheinin; Juhani Knuuti
PET in drug discovery and development: an introduction.
Annals of medicine 1999;31(6):430-1.
1999: Olli T Raitakari; Jyri O Toikka; Hanna Laine; J Viikari; Juhani Knuuti; Jaakko Hartiala
Reduced myocardial flow reserve does not impair exercise capacity in asymptomatic men.
The American journal of cardiology 1999;84(10):1253-5, A8.
1999: Teemu Takala; Pirjo Nuutila; C Katoh; Matti Luotolahti; J Bergman; Maija Mäki; Vesa Oikonen; Ulla Ruotsalainen; Tove Grönroos; Merja Haaparanta; Jukka Kapanen; Juhani Knuuti
Myocardial blood flow, oxygen consumption, and fatty acid uptake in endurance athletes during insulin stimulation.
The American journal of physiology 1999;277(4 Pt 1):E585-90.
1999: Risto Vesalainen; Mikko Pietilä; Kari U O Tahvanainen; Tuomas Jartti; Mika Teräs; Kjell Någren; Pertti Lehikoinen; Risto Huupponen; Heikki Ukkonen; Markku Saraste; Juhani Knuuti; Liisa-Maria Voipio-Pulkki
Cardiac positron emission tomography imaging with [11C]hydroxyephedrine, a specific tracer for sympathetic nerve endings, and its functional correlates in congestive heart failure.
The American journal of cardiology 1999;84(5):568-74.
1999: Anu K Turpeinen; Teemu Takala; Pirjo Nuutila; T Axelin; Matti Luotolahti; Merja Haaparanta; Jörgen Bergman; Helena Hämäläinen; H Iida; M Mäki; M I J Uusitupa; Juhani Knuuti
Impaired free fatty acid uptake in skeletal muscle but not in myocardium in patients with impaired glucose tolerance: studies with PET and 14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid.
Diabetes 1999;48(6):1245-50.
1999: C Katoh; Ulla Ruotsalainen; Hanna Laine; Sakari Alenius; H Iida; Pirjo Nuutila; Juhani Knuuti
Iterative reconstruction based on median root prior in quantification of myocardial blood flow and oxygen metabolism.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(5):862-7.
1999: Otto Pitkänen; Pirjo Nuutila; Olli T Raitakari; Kimmo Porkka; H Iida; Ilpo Nuotio; Tapani Rönnemaa; Jorma Viikari; Marja-Riitta Taskinen; C Ehnholm; Juhani Knuuti
Coronary flow reserve in young men with familial combined hyperlipidemia.
Circulation 1999;99(13):1678-84.
1999: Teemu Takala; Pirjo Nuutila; Juhani Knuuti; Matti Luotolahti; Hannele Yki-Järvinen
Insulin action on heart and skeletal muscle glucose uptake in weight lifters and endurance athletes.
The American journal of physiology 1999;276(4 Pt 1):E706-11.
1999: E M Rönnemaa; Tapani Rönnemaa; Tapio Utriainen; Maria Raitakari; Hanna Laine; Teemu Takala; Otto Pitkänen; Olli A Kirvelä; Juhani Knuuti; Pirjo Nuutila
Decreased blood flow but unaltered insulin sensitivity of glucose uptake in skeletal muscle of chronic smokers.
Metabolism: clinical and experimental 1999;48(2):239-44.
1998: Maija Mäki; Merja Haaparanta; Pirjo Nuutila; Vesa Oikonen; Matti Luotolahti; Olli Eskola; Juhani Knuuti
Free fatty acid uptake in the myocardium and skeletal muscle using fluorine-18-fluoro-6-thia-heptadecanoic acid.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(8):1320-7.
1998: Hanna Laine; Olli T Raitakari; H Niinikoski; Otto Pitkänen; H Iida; Jorma Viikari; Pirjo Nuutila; Juhani Knuuti
Early impairment of coronary flow reserve in young men with borderline hypertension.
Journal of the American College of Cardiology 1998;32(1):147-53.
1998: Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Tapio Utriainen; Vesa Oikonen; Maria Raitakari; Matti Luotolahti; Olli A Kirvelä; Paolo Vicini; C Cobelli; Pirjo Nuutila; Hannele Yki-Järvinen
Preserved relative dispersion but blunted stimulation of mean flow, absolute dispersion, and blood volume by insulin in skeletal muscle of patients with essential hypertension.
Circulation 1998;97(21):2146-53.
1998: Hanna Laine; H Yki-Jarvinen; O Kirvela; Tuula Tolvanen; Maria Raitakari; Olof Solin; Merja Haaparanta; Juhani Knuuti; Pirjo Nuutila
Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity.
The Journal of clinical investigation 1998;101(5):1156-62.
1998: Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Maria Raitakari; H Iida; Jukka Kapanen; Olli A Kirvelä; Merja Haaparanta; Hannele Yki-Järvinen; Pirjo Nuutila
Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle.
Journal of hypertension 1998;16(2):211-9.
1998: Otto Pitkänen; Pirjo Nuutila; Olli T Raitakari; Tapani Rönnemaa; Päivi J Koskinen; H Iida; Terho Lehtimäki; Hanna Laine; Teemu Takala; Jorma S A Viikari; Juhani Knuuti
Coronary flow reserve is reduced in young men with IDDM.
Diabetes 1998;47(2):248-54.
1997: S Leskinen; K Pulkki; Juhani Knuuti; Olli A Kirvelä; Pertti Lehikoinen; Kjell Någren; Ulla Ruotsalainen; Mika Teräs; U Wegelius; Eeva Salminen
Transport of carbon-11-methionine is enhanced by insulin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(12):1967-70.
1997: Maria Raitakari; Pirjo Nuutila; Juhani Knuuti; Olli T Raitakari; Hanna Laine; Ulla Ruotsalainen; Olli A Kirvelä; Teemu Takala; H Iida; Hannele Yki-Järvinen
Effects of insulin on blood flow and volume in skeletal muscle of patients with IDDM: studies using [15O]H2O, [15O]CO, and positron emission tomography.
Diabetes 1997;46(12):2017-21.
1997: Maija Mäki; Merja Haaparanta; Matti Luotolahti; Pirjo Nuutila; L M Voipio-Pulkki; JR Bergman; Olof Solin; Juhani Knuuti
Fatty acid uptake is preserved in chronically dysfunctional but viable myocardium.
The American journal of physiology 1997;273(5 Pt 2):H2473-80.
1997: M Mäki; Pirjo Nuutila; Hanna Laine; L M Voipio-Pulkki; Merja Haaparanta; Olof Solin; Juhani Knuuti
Myocardial glucose uptake in patients with NIDDM and stable coronary artery disease.
Diabetes 1997;46(9):1491-6.
1997: Olli T Raitakari; Otto Pitkänen; Terho Lehtimäki; Sanni Lahdenperä; H Iida; Seppo Ylä-Herttuala; Jukka S Luoma; K Mattila; T Nikkari; Marja-Riitta Taskinen; Jorma S A Viikari; Juhani Knuuti
In vivo low density lipoprotein oxidation relates to coronary reactivity in young men.
Journal of the American College of Cardiology 1997;30(1):97-102.
1997: O P Pitkanen; Olli T Raitakari; T Ronnemaa; Harri Niinikoski; Pirjo Nuutila; H Iida; Jorma S A Viikari; Juhani Knuuti
Influence of cardiovascular risk status on coronary flow reserve in healthy young men.
The American journal of cardiology 1997;79(12):1690-2.
1997: Heikki Ukkonen; Markku Saraste; Juha Akkila; Juhani Knuuti; Pertti Lehikoinen; Kjell Någren; Lasse Lehtonen; Liisa-Maria Voipio-Pulkki
Myocardial efficiency during calcium sensitization with levosimendan: a noninvasive study with positron emission tomography and echocardiography in healthy volunteers.
Clinical pharmacology and therapeutics 1997;61(5):596-607.
1997: Ulla Ruotsalainen; Maria Raitakari; Pirjo Nuutila; Vesa Oikonen; Hannu Sipilä; Mika Teräs; Juhani Knuuti; P M Bloomfield; H Iida
Quantitative blood flow measurement of skeletal muscle using oxygen-15-water and PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(2):314-9.
1997: Kimmo Malminiemi; Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Vesa Oikonen; Merja Haaparanta; Pirjo Nuutila
Acute effects of celiprolol on muscle blood flow and insulin sensitivity: studies using [15O]-water, [18F]-fluorodeoxyglucose and positron emission tomography.
European journal of clinical pharmacology 1997;52(1):19-26.
1996: Otto Pitkänen; Olli T Raitakari; Harri Niinikoski; Pirjo Nuutila; H Iida; Liisa-Maria Voipio-Pulkki; R Härkönen; U Wegelius; Tapani Rönnemaa; J Viikari; Juhani Knuuti
Coronary flow reserve is impaired in young men with familial hypercholesterolemia.
Journal of the American College of Cardiology 1996;28(7):1705-11.
1996: Maria Raitakari; Pirjo Nuutila; Ulla Ruotsalainen; Hanna Laine; Mika Teräs; H Iida; Sari Mäkimattila; Tapio Utriainen; Vesa Oikonen; Hannu Sipilä; Merja Haaparanta; Olof Solin; U Wegelius; Juhani Knuuti; Hannele Yki-Järvinen
Evidence for dissociation of insulin stimulation of blood flow and glucose uptake in human skeletal muscle: studies using [15O]H2O, [18F]fluoro-2-deoxy-D-glucose, and positron emission tomography.
Diabetes 1996;45(11):1471-7.
1996: Maria Raitakari; Pirjo Nuutila; Ulla Ruotsalainen; Mika Teräs; E Eronen; Hanna Laine; Olli T Raitakari; H Iida; Juhani Knuuti; Hannele Yki-Järvinen
Relationship between limb and muscle blood flow in man.
The Journal of physiology 1996;496 ( Pt 2)():543-9.
1996: Maija Mäki; Matti Luotolahti; Pirjo Nuutila; H Iida; Liisa-Maria Voipio-Pulkki; Ulla Ruotsalainen; Merja Haaparanta; Olof Solin; Jaakko Hartiala; R Härkönen; Juhani Knuuti
Glucose uptake in the chronically dysfunctional but viable myocardium.
Circulation 1996;93(9):1658-66.
1996: Pirjo Nuutila; Maria Raitakari; Hanna Laine; Olli A Kirvelä; Teemu Takala; Tapio Utriainen; Sari Mäkimattila; Otto Pitkänen; Ulla Ruotsalainen; H Iida; Juhani Knuuti; Hannele Yki-Järvinen
Role of blood flow in regulating insulin-stimulated glucose uptake in humans. Studies using bradykinin, [15O]water, and [18F]fluoro-deoxy-glucose and positron emission tomography.
The Journal of clinical investigation 1996;97(7):1741-7.
1995: Maria Raitakari; Juhani Knuuti; Ulla Ruotsalainen; Hanna Laine; P Mäkeä; Mika Teräs; Hannu Sipilä; T Niskanen; Olli T Raitakari; H Iida
Insulin increases blood volume in human skeletal muscle: studies using [15O]CO and positron emission tomography.
The American journal of physiology 1995;269(6 Pt 1):E1000-5.
1995: Juhani Knuuti; Pirjo Nuutila; Liisa-Maria Voipio-Pulkki
[18F]FDG in measuring myocardial glucose uptake.
Circulation 1995;92(10):3146-8.
1995: Pirjo Nuutila; Maija Mäki; Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Matti Luotolahti; Merja Haaparanta; Olof Solin; A Jula; V A Koivisto
Insulin action on heart and skeletal muscle glucose uptake in essential hypertension.
The Journal of clinical investigation 1995;96(2):1003-9.
1995: Juhani Knuuti; Maija Mäki; Hannele Yki-Järvinen; Liisa-Maria Voipio-Pulkki; R Härkönen; Merja Haaparanta; Pirjo Nuutila
The effect of insulin and FFA on myocardial glucose uptake.
Journal of molecular and cellular cardiology 1995;27(7):1359-67.
1995: Jaakko Hartiala; Juhani Knuuti
Imaging of the heart by MRI and PET.
Annals of medicine 1995;27(1):35-45.
1995: Pirjo Nuutila; Juhani Knuuti; Maija Mäki; Hanna Laine; Ulla Ruotsalainen; Mika Teräs; Merja Haaparanta; Olof Solin; Hannele Yki-Järvinen
Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography.
Diabetes 1995;44(1):31-6.
1994: Pirjo Nuutila; Juhani Knuuti; Maria Raitakari; Ulla Ruotsalainen; Mika Teräs; Liisa-Maria Voipio-Pulkki; Merja Haaparanta; Olof Solin; U Wegelius; Hannele Yki-Järvinen
Effect of antilipolysis on heart and skeletal muscle glucose uptake in overnight fasted humans.
The American journal of physiology 1994;267(6 Pt 1):E941-6.
1994: Juhani Knuuti; Hannele Yki-Järvinen; Liisa-Maria Voipio-Pulkki; Maija Mäki; Ulla Ruotsalainen; R Härkönen; Mika Teräs; Merja Haaparanta; Jörgen Bergman; Jaakko Hartiala
Enhancement of myocardial [fluorine-18]fluorodeoxyglucose uptake by a nicotinic acid derivative.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(6):989-98.
1994: Pirjo Nuutila; Juhani Knuuti; Olli Heinonen; Ulla Ruotsalainen; Mika Teräs; Jörgen Bergman; Olof Solin; Hannele Yki-Järvinen; Liisa-Maria Voipio-Pulkki; U Wegelius
Different alterations in the insulin-stimulated glucose uptake in the athlete's heart and skeletal muscle.
The Journal of clinical investigation 1994;93(5):2267-74.
1994: Juhani Knuuti; M Saraste; Pirjo Nuutila; R Härkönen; U Wegelius; A Haapanen; Jörgen Bergman; Merja Haaparanta; T Savunen; Liisa-Maria Voipio-Pulkki
Myocardial viability: fluorine-18-deoxyglucose positron emission tomography in prediction of wall motion recovery after revascularization.
American heart journal 1994;127(4 Pt 1):785-96.
1994: Heikki Minn; Pirjo Nuutila; Paula Lindholm; Ulla Ruotsalainen; Jörgen Bergman; Mika Teräs; Juhani Knuuti
In vivo effects of insulin on tumor and skeletal muscle glucose metabolism in patients with lymphoma.
Cancer 1994;73(5):1490-8.
1993: Juhani Knuuti; Pirjo Nuutila; Ulla Ruotsalainen; Mika Teräs; M Saraste; R Härkönen; A Ahonen; U Wegelius; A Haapanen; Jörgen Bergman
The value of quantitative analysis of glucose utilization in detection of myocardial viability by PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2068-75.
1993: Liisa-Maria Voipio-Pulkki; Pirjo Nuutila; Juhani Knuuti; Ulla Ruotsalainen; Merja Haaparanta; Mika Teräs; U Wegelius; V A Koivisto
Heart and skeletal muscle glucose disposal in type 2 diabetic patients as determined by positron emission tomography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2064-7.
1993: Pirjo Nuutila; Juhani Knuuti; Ulla Ruotsalainen; V A Koivisto; E Eronen; Mika Teräs; Jörgen Bergman; Merja Haaparanta; Liisa-Maria Voipio-Pulkki; J Viikari
Insulin resistance is localized to skeletal but not heart muscle in type 1 diabetes.
The American journal of physiology 1993;264(5 Pt 1):E756-62.
1992: Juhani Knuuti; Pirjo Nuutila; Ulla Ruotsalainen; M Saraste; R Härkönen; A Ahonen; Mika Teräs; Merja Haaparanta; U Wegelius; A Haapanen
Euglycemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(7):1255-62.
1992: Pirjo Nuutila; V A Koivisto; Juhani Knuuti; Ulla Ruotsalainen; Mika Teräs; Merja Haaparanta; Jörgen Bergman; Olof Solin; Liisa-Maria Voipio-Pulkki; U Wegelius
Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo.
The Journal of clinical investigation 1992;89(6):1767-74.