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Pablo Alejandro Silveira

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Jessica Stolp; Shirng-Wern Tsaih; Wenyu Zhang; Timothy Stearns; Harold Chapman; Yi-Guang Chen; Selwyn L Cox; Vivien Henck; David V Serreze; Pablo Alejandro Silveira
Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.
eliana marino; Pablo Alejandro Silveira; Jessica Stolp; Shane T Grey
B cell-directed therapies in type 1 diabetes.
Helen M McGuire; Alexis Vogelzang; Cindy S Ma; William E Hughes; Pablo Alejandro Silveira; Stuart G Tangye; Daniel Christ; David Fulcher; Marika Falcone; Cecile King
A subset of interleukin-21+ chemokine receptor CCR9+ T helper cells target accessory organs of the digestive system in autoimmunity.

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All Publications

2012: Jessica Stolp; Shirng-Wern Tsaih; Wenyu Zhang; Timothy Stearns; Harold Chapman; Yi-Guang Chen; Selwyn L Cox; Vivien Henck; David V Serreze; Pablo Alejandro Silveira
Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(3):1406-17.
2011: eliana marino; Pablo Alejandro Silveira; Jessica Stolp; Shane T Grey
B cell-directed therapies in type 1 diabetes.
Trends in immunology 2011;32(6):287-94.
2011: Helen M McGuire; Alexis Vogelzang; Cindy S Ma; William E Hughes; Pablo Alejandro Silveira; Stuart G Tangye; Daniel Christ; David Fulcher; Marika Falcone; Cecile King
A subset of interleukin-21+ chemokine receptor CCR9+ T helper cells target accessory organs of the digestive system in autoimmunity.
Immunity 2011;34(4):602-15.
2010: Selwyn Lewis Cox; Jessica Stolp; Nicole L Hallahan; Jacqueline Counotte; Wenyu Zhang; David V Serreze; Antony Basten; Pablo Alejandro Silveira
Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice.
European journal of immunology 2010;40(12):3413-25.
2010: Antony Basten; Pablo Alejandro Silveira
B-cell tolerance: mechanisms and implications.
Current opinion in immunology 2010;22(5):566-74.
2009: S Lewis Cox; Pablo Alejandro Silveira
Emerging roles for B lymphocytes in Type 1 diabetes.
Expert review of clinical immunology 2009;5(3):311-24.
2008: François D Dufour; Pablo Alejandro Silveira; Alan G Baxter
Interactions between B-lymphocytes and type 1 NKT cells in autoimmune diabetes.
Journal of immunotoxicology 2008;5(2):249-57.
2007: Desmond K Y Ang; Thomas C Brodnicki; Margaret A Jordan; Wendy E Wilson; Pablo Alejandro Silveira; Briony L Gliddon; Alan G Baxter; Ian R van Driel
Two genetic loci independently confer susceptibility to autoimmune gastritis.
International immunology 2007;19(9):1135-44.
2007: Yi-Guang Chen; John P Driver; Pablo Alejandro Silveira; David V Serreze
Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice.
Immunogenetics 2007;59(9):705-12.
2007: Fabienne Mackay; Pablo Alejandro Silveira; Robert Brink
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling.
Current opinion in immunology 2007;19(3):327-36.
2007: Yi-Guang Chen; Pablo Alejandro Silveira; Melissa A Osborne; Harold D Chapman; David V Serreze
Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.
Diabetes 2007;56(2):424-30.
2007: Pablo Alejandro Silveira; David V Serreze; Shane T Grey
Invasion of the killer B's in type 1 diabetes.
Frontiers in bioscience : a journal and virtual library 2007;12():2183-93.
2006: Pablo Alejandro Silveira; Harold D Chapman; Jessica Stolp; Ellis Johnson; S Lewis Cox; Kara Hunter; Linda S Wicker; David V Serreze
Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7033-41.
2006: Pablo Alejandro Silveira; Shane T Grey
B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes.
Trends in endocrinology and metabolism: TEM 2006;17(4):128-35.
2005: Peter C Reifsnyder; Renhua Li; Pablo Alejandro Silveira; Gary Churchill; David V Serreze; Edward H Leiter
Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.
Genes and immunity 2005;6(6):528-38.
2005: Alan G Baxter; Margaret A Jordan; Pablo Alejandro Silveira; Wendy E Wilson; Ian R van Driel
Genetic control of susceptibility to autoimmune gastritis.
International reviews of immunology 2005;24(1-2):55-62.
2004: Pablo Alejandro Silveira; Joseph Dombrowsky; Ellis Johnson; Harold D Chapman; David Nemazee; David V Serreze
B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):5086-94.
2003: David V Serreze; Pablo Alejandro Silveira
The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes.
Current directions in autoimmunity 2003;6():212-27.
2002: Pablo Alejandro Silveira; Ellis Johnson; Harold D Chapman; Thi Bui; Roland Tisch; David V Serreze
The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors.
European journal of immunology 2002;32(12):3657-66.
2002: Ian R van Driel; Alan G Baxter; Karen L Laurie; Tricia D Zwar; Nicole L La Gruta; Louise M Judd; Katrina L Scarff; Pablo Alejandro Silveira; Paul A Gleeson
Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis.
Autoimmunity reviews 2002;1(5):290-7.
2001: Pablo Alejandro Silveira; Wendy E Wilson; Luis M Esteban; Margaret A Jordan; Christine G Hawke; Ian R van Driel; Alan G Baxter
Identification of the Gasa3 and Gasa4 autoimmune gastritis susceptibility genes using congenic mice and partitioned, segregative and interaction analyses.
Immunogenetics 2001;53(9):741-50.
2001: David V Serreze; Ellis A Johnson; Harold D Chapman; Robert T Graser; Michele P Marron; Teresa P DiLorenzo; Pablo Alejandro Silveira; Y Yoshimura; Stanley G Nathenson; S Joyce
Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Diabetes 2001;50(9):1992-2000.
2001: Ellis A Johnson; Pablo Alejandro Silveira; Harold D Chapman; Edward H Leiter; David V Serreze
Inhibition of autoimmune diabetes in nonobese diabetic mice by transgenic restoration of H2-E MHC class II expression: additive, but unequal, involvement of multiple APC subtypes.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2404-10.
2001: Lynn D Poulton; Mark J Smyth; Christine G Hawke; Pablo Alejandro Silveira; D Shepherd; Olga V Naidenko; Dale I Godfrey; Alan G Baxter
Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.
International immunology 2001;13(7):887-96.
2001: Pablo Alejandro Silveira; Alan G Baxter
The NOD mouse as a model of SLE.
Autoimmunity 2001;34(1):53-64.
2000: Margaret A Jordan; Pablo Alejandro Silveira; D P Shepherd; C Chu; SJ Kinder; J Chen; L J Palmisano; Lynn D Poulton; Alan G Baxter
Linkage analysis of systemic lupus erythematosus induced in diabetes-prone nonobese diabetic mice by Mycobacterium bovis.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1673-84.
1999: Pablo Alejandro Silveira; Alan G Baxter; W E Cain; Ian R van Driel
A major linkage region on distal chromosome 4 confers susceptibility to mouse autoimmune gastritis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5106-11.
1998: Pablo Alejandro Silveira; R Howson; P Silveira; david williams; Alan G Baxter
Characterization and specificity of B-cell responses in lupus induced by Mycobacterium bovis in NOD/Lt mice.
Immunology 1998;95(1):8-17.
1998: Kirsten J L Hammond; Lynn D Poulton; L J Palmisano; Pablo Alejandro Silveira; Dale I Godfrey; Alan G Baxter
alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.
The Journal of experimental medicine 1998;187(7):1047-56.
1997: Dale I Godfrey; SJ Kinder; Pablo Alejandro Silveira; Alan G Baxter
Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes.
Journal of autoimmunity 1997;10(3):279-85.