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Pierre Chambon

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Golonzhka Olga; Liang Xiaobo; Messaddeq Nadia; Bornert Jean-Marc; Campbell Adam L; Metzger Daniel; Chambon Pierre; Ganguli-Indra Gitali; Leid Mark; Indra Arup K
Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation.
Mascrez Bénédicte; Ghyselinck Norbert B; Chambon Pierre; Mark Manuel
A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.
Zhang Zhikun; Hener Pierre; Frossard Nelly; Kato Shigeaki; Metzger Daniel; Li Mei; Chambon Pierre
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.

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All Publications

2009: Golonzhka Olga; Liang Xiaobo; Messaddeq Nadia; Bornert Jean-Marc; Campbell Adam L; Metzger Daniel; Chambon Pierre; Ganguli-Indra Gitali; Leid Mark; Indra Arup K
Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation.
The Journal of investigative dermatology 2009;129(6):1459-70.
2009: Mascrez Bénédicte; Ghyselinck Norbert B; Chambon Pierre; Mark Manuel
A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4272-7.
2009: Zhang Zhikun; Hener Pierre; Frossard Nelly; Kato Shigeaki; Metzger Daniel; Li Mei; Chambon Pierre
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1536-41.
2009: Toutain Céline E; Brouchet Laurent; Raymond-Letron Isabelle; Vicendo Patricia; Bergès Hortense; Favre Julie; Fouque Marie-José; Krust Andrée; Schmitt Anne-Marie; Chambon Pierre; Gourdy Pierre; Arnal Jean-François; Lenfant Françoise
Prevention of skin flap necrosis by estradiol involves reperfusion of a protected vascular network.
Circulation research 2009;104(2):245-54, 12p following 254.
2009: Wendling Olivia; Bornert Jean-Marc; Chambon Pierre; Metzger Daniel
Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse.
Genesis (New York, N.Y. : 2000) 2009;47(1):14-8.
2009: Mark Manuel; Ghyselinck Norbert B; Chambon Pierre
Function of retinoic acid receptors during embryonic development.
Nuclear receptor signaling 2009;7():e002.
2008: Hill Jonathan A; Hall Jason A; Sun Cheng-Ming; Cai Qi; Ghyselinck Norbert; Chambon Pierre; Belkaid Yasmine; Mathis Diane; Benoist Christophe
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.
Immunity 2008;29(5):758-70.
2008: Mark Manuel; Jacobs Hugues; Oulad-Abdelghani Mustapha; Dennefeld Christine; Féret Betty; Vernet Nadège; Codreanu Carmen-Alina; Chambon Pierre; Ghyselinck Norbert B
STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation.
Journal of cell science 2008;121(Pt 19):3233-42.
2008: Mandillo Silvia; Tucci Valter; Hölter Sabine M; Meziane Hamid; Banchaabouchi Mumna Al; Kallnik Magdalena; Lad Heena V; Nolan Patrick M; Ouagazzal Abdel-Mouttalib; Coghill Emma L; Gale Karin; Golini Elisabetta; Jacquot Sylvie; Krezel Wojtek; Parker Andy; Riet Fabrice; Schneider Ilka; Marazziti Daniela; Auwerx Johan; Brown Steve D M; Chambon Pierre; Rosenthal Nadia; Tocchini-Valentini Glauco; Wurst Wolfgang
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study.
Physiological genomics 2008;34(3):243-55.
2008: Küppers Eva; Krust Andre; Chambon Pierre; Beyer Cordian
Functional alterations of the nigrostriatal dopamine system in estrogen receptor-alpha knockout (ERKO) mice.
Psychoneuroendocrinology 2008;33(6):832-8.
2008: Konishi Morichika; Nakamura Hirotoshi; Miwa Hiroyuki; Chambon Pierre; Ornitz David M; Itoh Nobuyuki
Role of Fgf receptor 2c in adipocyte hypertrophy in mesenteric white adipose tissue.
Molecular and cellular endocrinology 2008;287(1-2):13-9.
2008: Liao Wen-Lin; Tsai Hsiu-Chao; Wang Hsiao-Fang; Chang Josephine; Lu Kuan-Ming; Wu Hsiao-Lin; Lee Yi-Chao; Tsai Ting-Fen; Takahashi Hiroshi; Wagner Michael; Ghyselinck Norbert B; Chambon Pierre; Liu Fu-Chin
Modular patterning of structure and function of the striatum by retinoid receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6765-70.
2008: Malanchi Ilaria; Peinado Hector; Kassen Deepika; Hussenet Thomas; Metzger Daniel; Chambon Pierre; Huber Marcel; Hohl Daniel; Cano Amparo; Birchmeier Walter; Huelsken Joerg
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Nature 2008;452(7187):650-3.
2008: Douin-Echinard Victorine; Laffont Sophie; Seillet Cyril; Delpy Laurent; Krust Andrée; Chambon Pierre; Gourdy Pierre; Arnal Jean-François; Guéry Jean-Charles
Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):3661-9.
2008: Ignat Mihaela; Teletin Marius; Tisserand Johan; Khetchoumian Konstantin; Dennefeld Christine; Chambon Pierre; Losson Régine; Mark Manuel
Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2598-603.
2008: Orengo James P; Chambon Pierre; Metzger Daniel; Mosier Dennis R; Snipes G Jackson; Cooper Thomas A
Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2646-51.
2008: Ratnacaram Chandrahas Koumar; Teletin Marius; Jiang Ming; Meng Xiangjun; Chambon Pierre; Metzger Daniel
Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2521-6.
2008: Antal Maria Cristina; Krust Andrée; Chambon Pierre; Mark Manuel
Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2433-8.
2007: Ruiz Alberto; Ghyselinck Norbert B; Mata Nathan; Nusinowitz Steven; Lloyd Marcia; Dennefeld Christine; Chambon Pierre; Bok Dean
Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage.
Investigative ophthalmology & visual science 2007;48(12):5377-87.
2007: Khetchoumian Konstantin; Teletin Marius; Tisserand Johan; Mark Manuel; Herquel Benjamin; Ignat Mihaela; Zucman-Rossi Jessica; Cammas Florence; Lerouge Thierry; Thibault Christelle; Metzger Daniel; Chambon Pierre; Losson Régine
Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.
Nature genetics 2007;39(12):1500-6.
2007: Slezak Michal; Göritz Christian; Niemiec Aurore; Frisén Jonas; Chambon Pierre; Metzger Daniel; Pfrieger Frank W
Transgenic mice for conditional gene manipulation in astroglial cells.
Glia 2007;55(15):1565-76.
2007: MacLean Glenn; Li Hui; Metzger Daniel; Chambon Pierre; Petkovich Martin
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice.
Endocrinology 2007;148(10):4560-7.
2007: Dali-Youcef Nassim; Mataki Chikage; Coste Agnès; Messaddeq Nadia; Giroud Sylvain; Blanc Stéphane; Koehl Christian; Champy Marie-France; Chambon Pierre; Fajas Lluis; Metzger Daniel; Schoonjans Kristina; Auwerx Johan
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10703-8.
2007: Indra Arup Kumar; Castaneda Eduardo; Antal Maria Cristina; Jiang Ming; Messaddeq Nadia; Meng Xiangjun; Loehr Christiane V; Gariglio Patricio; Kato Shigeaki; Wahli Walter; Desvergne Béatrice; Metzger Daniel; Chambon Pierre
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
The Journal of investigative dermatology 2007;127(5):1250-60.
2007: Mukai Hideo; Tsurugizawa Tomokazu; Murakami Gen; Kominami Shiro; Ishii Hirotaka; Ogiue-Ikeda Mari; Takata Norio; Tanabe Nobuaki; Furukawa Aizo; Hojo Yasushi; Ooishi Yuuki; Morrison John H; Janssen William G M; Rose John A; Chambon Pierre; Kato Shigeaki; Izumi Shunsuke; Yamazaki Takeshi; Kimoto Tetsuya; Kawato Suguru
Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons.
Journal of neurochemistry 2007;100(4):950-67.
2007: Metzger D; Chambon P
Contribution of targeted conditional somatic mutagenesis to deciphering retinoid X receptor functions and to generating mouse models of human diseases.
Handbook of experimental pharmacology 2007;(178):511-24.
2006: Germain Pierre; Chambon Pierre; Eichele Gregor; Evans Ronald M; Lazar Mitchell A; Leid Mark; De Lera Angel R; Lotan Reuben; Mangelsdorf David J; Gronemeyer Hinrich
International Union of Pharmacology. LXIII. Retinoid X receptors.
Pharmacological reviews 2006;58(4):760-72.
2006: Germain Pierre; Chambon Pierre; Eichele Gregor; Evans Ronald M; Lazar Mitchell A; Leid Mark; De Lera Angel R; Lotan Reuben; Mangelsdorf David J; Gronemeyer Hinrich
International Union of Pharmacology. LX. Retinoic acid receptors.
Pharmacological reviews 2006;58(4):712-25.
2006: Vernet Nadège; Dennefeld Christine; Guillou Florian; Chambon Pierre; Ghyselinck Norbert B; Mark Manuel
Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.
The EMBO journal 2006;25(24):5816-25.
2006: Schuler Michael; Ali Faisal; Chambon Céline; Duteil Delphine; Bornert Jean-Marc; Tardivel Aubry; Desvergne Béatrice; Wahli Walter; Chambon Pierre; Metzger Daniel
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes.
Cell metabolism 2006;4(5):407-14.
2006: Mukherjee Atish; Soyal Selma M; Fernandez-Valdivia Rodrigo; Gehin Martine; Chambon Pierre; Demayo Francesco J; Lydon John P; O'Malley Bert W
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse.
Molecular and cellular biology 2006;26(17):6571-83.
2006: Li Mei; Hener Pierre; Zhang Zhikun; Kato Shigeaki; Metzger Daniel; Chambon Pierre
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11736-41.
2006: Calléja Cécile; Messaddeq Nadia; Chapellier Benoit; Yang Haiyuan; Krezel Wojciech; Li Mei; Metzger Daniel; Mascrez Bénédicte; Ohta Kiminori; Kagechika Hiroyuki; Endo Yasuyuki; Mark Manuel; Ghyselinck Norbert B; Chambon Pierre
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.
Genes & development 2006;20(11):1525-38.
2006: Ghyselinck Norbert B; Vernet Nadège; Dennefeld Christine; Giese Norbert; Nau Heinz; Chambon Pierre; Viville Stéphane; Mark Manuel
Retinoids and spermatogenesis: lessons from mutant mice lacking the plasma retinol binding protein.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(6):1608-22.
2006: Vermot Julien; Garnier Jean-Marie; Dierich Andrée; Niederreither Karen; Harvey Richard P; Chambon Pierre; Dollé Pascal
Conditional (loxP-flanked) allele for the gene encoding the retinoic acid-synthesizing enzyme retinaldehyde dehydrogenase 2 (RALDH2).
Genesis (New York, N.Y. : 2000) 2006;44(3):155-8.
2006: Vernet Nadège; Dennefeld Christine; Rochette-Egly Cécile; Oulad-Abdelghani Mustapha; Chambon Pierre; Ghyselinck Norbert B; Mark Manuel
Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis.
Endocrinology 2006;147(1):96-110.
2006: Mark Manuel; Ghyselinck Norbert B; Chambon Pierre
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis.
Annual review of pharmacology and toxicology 2006;46():451-80.
2005: Argmann Carmen A; Chambon Pierre; Auwerx Johan
Mouse phenogenomics: the fast track to "systems metabolism".
Cell metabolism 2005;2(6):349-60.
2005: Matt Nicolas; Dupé Valérie; Garnier Jean-Marie; Dennefeld Christine; Chambon Pierre; Mark Manuel; Ghyselinck Norbert B
Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells.
Development (Cambridge, England) 2005;132(21):4789-800.
2005: Li Mei; Messaddeq Nadia; Teletin Marius; Pasquali Jean-Louis; Metzger Daniel; Chambon Pierre
Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14795-800.
2005: Indra Arup Kumar; Dupé Valérie; Bornert Jean-Marc; Messaddeq Nadia; Yaniv Moshe; Mark Manuel; Chambon Pierre; Metzger Daniel
Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.
Development (Cambridge, England) 2005;132(20):4533-44.
2005: Hoegberg Pi; Schmidt Carsten K; Fletcher Nick; Nilsson Charlotte B; Trossvik Christina; Gerlienke Schuur A; Brouwer Abraham; Nau Heinz; Ghyselinck Norbert B; Chambon Pierre; Håkansson Helen
Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms.
Chemico-biological interactions 2005;156(1):25-39.
2005: Metzger D; Imai T; Jiang M; Takukawa R; Desvergne B; Wahli W; Chambon P
Functional role of RXRs and PPARgamma in mature adipocytes.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(1):51-8.
2005: Chambon Pierre
The nuclear receptor superfamily: a personal retrospect on the first two decades.
Molecular endocrinology (Baltimore, Md.) 2005;19(6):1418-28.
2005: Wietrzych Marta; Meziane Hamid; Sutter Anne; Ghyselinck Norbert; Chapman Paul F; Chambon Pierre; Krezel Wojciech
Working memory deficits in retinoid X receptor gamma-deficient mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(3):318-26.
2005: Schnütgen Frank; De-Zolt Silke; Van Sloun Petra; Hollatz Melanie; Floss Thomas; Hansen Jens; Altschmied Joachim; Seisenberger Claudia; Ghyselinck Norbert B; Ruiz Patricia; Chambon Pierre; Wurst Wolfgang; von Melchner Harald
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7221-6.
2005: Matt Nicolas; Schmidt Carsten K; Dupé Valérie; Dennefeld Christine; Nau Heinz; Chambon Pierre; Mark Manuel; Ghyselinck Norbert B
Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(1):167-76.
2005: Schuler Michael; Ali Faisal; Metzger Elisabeth; Chambon Pierre; Metzger Daniel
Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse.
Genesis (New York, N.Y. : 2000) 2005;41(4):165-70.
2005: Vermot Julien; Schuhbaur Brigitte; Le Mouellic Hervé; McCaffery Peter; Garnier Jean-Marie; Hentsch Didier; Brûlet Philippe; Niederreither Karen; Chambon Pierre; Dollé Pascal; Le Roux Isabelle
Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons.
Development (Cambridge, England) 2005;132(7):1611-21.
2005: Vermot Julien; Gallego Llamas Jabier; Fraulob Valérie; Niederreither Karen; Chambon Pierre; Dollé Pascal
Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo.
Science (New York, N.Y.) 2005;308(5721):563-6.
2005: Serpente Patricia; Tümpel Stefan; Ghyselinck Norbert B; Niederreither Karen; Wiedemann Leanne M; Dollé Pascal; Chambon Pierre; Krumlauf Robb; Gould Alex P
Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation.
Development (Cambridge, England) 2005;132(3):503-13.
2005: Metzger Daniel; Li Mei; Chambon Pierre
Targeted somatic mutagenesis in the mouse epidermis.
Methods in molecular biology (Clifton, N.J.) 2005;289():329-40.
2004: Khetchoumian Konstantin; Teletin Marius; Mark Manuel; Lerouge Thierry; Cerviño Margarita; Oulad-Abdelghani Mustapha; Chambon Pierre; Losson Régine
TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.
The Journal of biological chemistry 2004;279(46):48329-41.
2004: Champy Marie-France; Selloum Mohammed; Piard Laetitia; Zeitler Valerie; Caradec Claudia; Chambon Pierre; Auwerx Johan
Mouse functional genomics requires standardization of mouse handling and housing conditions.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(10):768-83.
2004: Chambon Pierre
How I became one of the fathers of a superfamily.
Nature medicine 2004;10(10):1027-31.
2004: Mark Manuel; Ghyselinck Norbert B; Chambon Pierre
Retinoic acid signalling in the development of branchial arches.
Current opinion in genetics & development 2004;14(5):591-8.
2004: Cammas Florence; Herzog Marielle; Lerouge Thierry; Chambon Pierre; Losson Régine
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation.
Genes & development 2004;18(17):2147-60.
2004: Yamada Takashi; Kawano Hirotaka; Sekine Keisuke; Matsumoto Takahiro; Fukuda Toru; Azuma Yoshiaki; Itaka Keiji; Chung Ung-il; Chambon Pierre; Nakamura Kozo; Kato Shigeaki; Kawaguchi Hiroshi
SRC-1 is necessary for skeletal responses to sex hormones in both males and females.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(9):1452-61.
2004: Garidou Lucile; Laffont Sophie; Douin-Echinard Victorine; Coureau Christiane; Krust Andrée; Chambon Pierre; Guéry Jean-Charles
Estrogen receptor alpha signaling in inflammatory leukocytes is dispensable for 17beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2435-42.
2004: Yan Kai-Ping; Dollé Pascal; Mark Manuel; Lerouge Thierry; Wendling Olivia; Chambon Pierre; Losson Régine
Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene.
Gene 2004;334():3-13.
2004: Nielsen Anders Lade; Jørgensen Poul; Lerouge Thierry; Cerviño Margarita; Chambon Pierre; Losson Régine
Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif.
Molecular and cellular biology 2004;24(12):5184-96.
2004: Imai Takeshi; Takakuwa Reiko; Marchand Sandra; Dentz Emilie; Bornert Jean-Marc; Messaddeq Nadia; Wendling Olivia; Mark Manuel; Desvergne Béatrice; Wahli Walter; Chambon Pierre; Metzger Daniel
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4543-7.
2004: Mark Manuel; Yoshida-Komiya Hiromi; Gehin Martine; Liao Lan; Tsai Ming-Jer; O'Malley Bert W; Chambon Pierre; Xu Jianming
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4453-8.
2004: Mascrez Bénédicte; Ghyselinck Norbert B; Watanabe Mitsuhiro; Annicotte Jean-Sébastien; Chambon Pierre; Auwerx Johan; Mark Manuel
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
EMBO reports 2004;5(3):285-90.
2004: Mori Mikiro; Metzger Daniel; Picaud Serge; Hindelang Colette; Simonutti Manuel; Sahel José; Chambon Pierre; Mark Manuel
Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium.
The American journal of pathology 2004;164(2):701-10.
2004: Oudet Pierre; Chambon Pierre
Seeing is believing.
Cell 2004;116(2 Suppl):S79-80, 1 p following S80.
2003: Dupé Valérie; Matt Nicolas; Garnier Jean-Marie; Chambon Pierre; Mark Manuel; Ghyselinck Norbert B
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14036-41.
2003: Rayasam Geetha Vani; Wendling Olivia; Angrand Pierre-Olivier; Mark Manuel; Niederreither Karen; Song Luyan; Lerouge Thierry; Hager Gordon L; Chambon Pierre; Losson Régine
NSD1 is essential for early post-implantation development and has a catalytically active SET domain.
The EMBO journal 2003;22(12):3153-63.
2003: Niederreither Karen; Vermot Julien; Le Roux Isabelle; Schuhbaur Brigitte; Chambon Pierre; Dollé Pascal
The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system.
Development (Cambridge, England) 2003;130(11):2525-34.
2003: Ménissier de Murcia Josiane; Ricoul Michelle; Tartier Laurence; Niedergang Claude; Huber Aline; Dantzer Françoise; Schreiber Valérie; Amé Jean-Christophe; Dierich Andrée; LeMeur Marianne; Sabatier Laure; Chambon Pierre; de Murcia Gilbert
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse.
The EMBO journal 2003;22(9):2255-63.
2003: Matt Nicolas; Ghyselinck Norbert B; Wendling Olivia; Chambon Pierre; Mark Manuel
Retinoic acid-induced developmental defects are mediated by RARbeta/RXR heterodimers in the pharyngeal endoderm.
Development (Cambridge, England) 2003;130(10):2083-93.
2003: Schnütgen Frank; Doerflinger Nathalie; Calléja Cécile; Wendling Olivia; Chambon Pierre; Ghyselinck Norbert B
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse.
Nature biotechnology 2003;21(5):562-5.
2003: Abu-Abed Suzan; Dollé Pascal; Metzger Daniel; Wood Caroline; MacLean Glenn; Chambon Pierre; Petkovich Martin
Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1.
Development (Cambridge, England) 2003;130(7):1449-59.
2003: Maret Arlette; Coudert Jérôme D; Garidou Lucile; Foucras Gilles; Gourdy Pierre; Krust Andrée; Dupont Sonia; Chambon Pierre; Druet Philippe; Bayard Francis; Guéry Jean-Charles
Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells.
European journal of immunology 2003;33(2):512-21.
2003: Vermot Julien; Niederreither Karen; Garnier Jean-Marie; Chambon Pierre; Dollé Pascal
Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1763-8.
2003: Weber Philipp; Schuler Michael; Gérard Christelle; Mark Manuel; Metzger Daniel; Chambon Pierre
Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis.
Biology of reproduction 2003;68(2):553-9.
2003: Oosterveen Tony; Niederreither Karen; Dollé Pascal; Chambon Pierre; Meijlink Frits; Deschamps Jacqueline
Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain.
The EMBO journal 2003;22(2):262-9.
2003: Dupont Sonia; Dennefeld Christine; Krust Andrée; Chambon Pierre; Mark Manuel
Expression of Sox9 in granulosa cells lacking the estrogen receptors, ERalpha and ERbeta.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;226(1):103-6.
2003: Metzger Daniel; Indra Arup Kumar; Li Mei; Chapellier Benoit; Calleja Cécile; Ghyselinck Norbert B; Chambon Pierre
Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes.
Methods in enzymology 2003;364():379-408.
2002: Picard Frédéric; Géhin Martine; Annicotte Jean- Sébastien; Rocchi Stéphane; Champy Marie-France; O'Malley Bert W; Chambon Pierre; Auwerx Johan
SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
Cell 2002;111(7):931-41.
2002: Romand Raymond; Hashino Eri; Dollé Pascal; Vonesch Jean-Luc; Chambon Pierre; Ghyselinck Norbert B
The retinoic acid receptors RARalpha and RARgamma are required for inner ear development.
Mechanisms of development 2002;119(2):213-23.
2002: Niederreither Karen; Vermot Julien; Fraulob Valerie; Chambon Pierre; Dolle Pascal
Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16111-6.
2002: Nielsen Anders Lade; Sanchez Cecilia; Ichinose Hiroshi; Cerviño Margarita; Lerouge Thierry; Chambon Pierre; Losson Régine
Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha.
The EMBO journal 2002;21(21):5797-806.
2002: Cammas Florence; Oulad-Abdelghani Mustapha; Vonesch Jean-Luc; Huss-Garcia Yolande; Chambon Pierre; Losson Régine
Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction.
Journal of cell science 2002;115(Pt 17):3439-48.
2002: Gehin Martine; Mark Manuel; Dennefeld Christine; Dierich Andrée; Gronemeyer Hinrich; Chambon Pierre
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.
Molecular and cellular biology 2002;22(16):5923-37.
2002: Niederreither Karen; Vermot Julien; Schuhbaur Brigitte; Chambon Pierre; Dollé Pascal
Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse.
Development (Cambridge, England) 2002;129(15):3563-74.
2002: Bastien Julie; Adam-Stitah Sylvie; Plassat Jean-Luc; Chambon Pierre; Rochette-Egly Cecile
The phosphorylation site located in the A region of retinoic X receptor alpha is required for the antiproliferative effect of retinoic acid (RA) and the activation of RA target genes in F9 cells.
The Journal of biological chemistry 2002;277(32):28683-9.
2002: Giannì Maurizio; Bauer Annie; Garattini Enrico; Chambon Pierre; Rochette-Egly Cécile
Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation.
The EMBO journal 2002;21(14):3760-9.
2002: Chapellier Benoit; Mark Manuel; Messaddeq Nadia; Calléja Cécile; Warot Xavier; Brocard Jacques; Gérard Christelle; Li Mei; Metzger Daniel; Ghyselinck Norbert B; Chambon Pierre
Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.
The EMBO journal 2002;21(13):3402-13.
2002: Gianni Maurizio; Kopf Eliezer; Bastien Julie; Oulad-Abdelghani Mustapha; Garattini Enrico; Chambon Pierre; Rochette-Egly Cecile
Down-regulation of the phosphatidylinositol 3-kinase/Akt pathway is involved in retinoic acid-induced phosphorylation, degradation, and transcriptional activity of retinoic acid receptor gamma 2.
The Journal of biological chemistry 2002;277(28):24859-62.
2002: Benecke Arndt; Gaudon Claudine; Garnier Jean-Marie; vom Baur Elmar; Chambon Pierre; Losson Régine
ADA3-containing complexes associate with estrogen receptor alpha.
Nucleic acids research 2002;30(11):2508-14.
2002: Ghyselinck N B; Chapellier B; Calléja C; Kumar Indra A; Li M; Messaddeq N; Mark M; Metzger D; Chambon P
[Genetic dissection of retinoic acid function in epidermis physiology]
Annales de dermatologie et de vénéréologie 2002;129(5 Pt 2):793-9.
2002: Weber Philipp; Cammas Florence; Gerard Christelle; Metzger Daniel; Chambon Pierre; Losson Régine; Mark Manuel
Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse.
Development (Cambridge, England) 2002;129(10):2329-37.
2002: Niederreither Karen; Abu-Abed Suzan; Schuhbaur Brigitte; Petkovich Martin; Chambon Pierre; Dollé Pascal
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development.
Nature genetics 2002;31(1):84-8.
2002: Darblade B; Pendaries C; Krust A; Dupont S; Fouque M-J; Rami J; Chambon P; Bayard F; Arnal J-F
Estradiol alters nitric oxide production in the mouse aorta through the alpha-, but not beta-, estrogen receptor.
Circulation research 2002;90(4):413-9.
2002: Tini Marc; Benecke Arndt; Um Soo-Joong; Torchia Joseph; Evans Ronald M; Chambon Pierre
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription.
Molecular cell 2002;9(2):265-77.
2002: Chapellier Benoit; Mark Manuel; Garnier Jean-Marie; Dierich Andrée; Chambon Pierre; Ghyselinck Norbert B
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):95-8.
2002: Chapellier Benoit; Mark Manuel; Bastien Julie; Dierich Andrée; LeMeur Marianne; Chambon Pierre; Ghyselinck Norbert B
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):91-4.
2002: Chapellier Benoit; Mark Manuel; Garnier Jean-Marie; LeMeur Marianne; Chambon Pierre; Ghyselinck Norbert B
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor alpha (RARalpha) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):87-90.
2002: Pendaries C; Darblade B; Rochaix P; Krust A; Chambon P; Korach K S; Bayard F; Arnal J F
The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2205-10.
2002: Abu-Abed Suzan; MacLean Glenn; Fraulob Valérie; Chambon Pierre; Petkovich Martin; Dollé Pascal
Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis.
Mechanisms of development 2002;110(1-2):173-7.
2002: Niederreither Karen; Fraulob Valérie; Garnier Jean-Marie; Chambon Pierre; Dollé Pascal
Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse.
Mechanisms of development 2002;110(1-2):165-71.
2001: Weber P; Metzger D; Chambon P
Temporally controlled targeted somatic mutagenesis in the mouse brain.
The European journal of neuroscience 2001;14(11):1777-83.
2001: Krezel W; Dupont S; Krust A; Chambon P; Chapman P F
Increased anxiety and synaptic plasticity in estrogen receptor beta -deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(21):12278-82.
2001: MacLean G; Abu-Abed S; Dollé P; Tahayato A; Chambon P; Petkovich M
Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development.
Mechanisms of development 2001;107(1-2):195-201.
2001: Romand R; Albuisson E; Niederreither K; Fraulob V; Chambon P; Dollé P
Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development.
Mechanisms of development 2001;106(1-2):185-9.
2001: Rochette-Egly C; Chambon P
F9 embryocarcinoma cells: a cell autonomous model to study the functional selectivity of RARs and RXRs in retinoid signaling.
Histology and histopathology 2001;16(3):909-22.
2001: Mascrez B; Mark M; Krezel W; Dupé V; LeMeur M; Ghyselinck N B; Chambon P
Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.
Development (Cambridge, England) 2001;128(11):2049-62.
2001: Wendling O; Ghyselinck N B; Chambon P; Mark M
Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning.
Development (Cambridge, England) 2001;128(11):2031-8.
2001: Dilworth F J; Chambon P
Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription.
Oncogene 2001;20(24):3047-54.
2001: Angrand P O; Apiou F; Stewart A F; Dutrillaux B; Losson R; Chambon P
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines.
Genomics 2001;74(1):79-88.
2001: Mori M; Ghyselinck N B; Chambon P; Mark M
Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.
Investigative ophthalmology & visual science 2001;42(6):1312-8.
2001: Metzger D; Chambon P
Site- and time-specific gene targeting in the mouse.
Methods (San Diego, Calif.) 2001;24(1):71-80.
2001: van den Akker E; Fromental-Ramain C; de Graaff W; Le Mouellic H; Brûlet P; Chambon P; Deschamps J
Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes.
Development (Cambridge, England) 2001;128(10):1911-21.
2001: Beckstead R; Ortiz J A; Sanchez C; Prokopenko S N; Chambon P; Losson R; Bellen H J
Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription.
Molecular cell 2001;7(4):753-65.
2001: Nielsen A L; Oulad-Abdelghani M; Ortiz J A; Remboutsika E; Chambon P; Losson R
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins.
Molecular cell 2001;7(4):729-39.
2001: Imai T; Jiang M; Kastner P; Chambon P; Metzger D
Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4581-6.
2001: Niederreither K; Vermot J; Messaddeq N; Schuhbaur B; Chambon P; Dollé P
Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.
Development (Cambridge, England) 2001;128(7):1019-31.
2001: Kastner P; Lawrence H J; Waltzinger C; Ghyselinck N B; Chambon P; Chan S
Positive and negative regulation of granulopoiesis by endogenous RARalpha.
Blood 2001;97(5):1314-20.
2001: Li M; Chiba H; Warot X; Messaddeq N; Gérard C; Chambon P; Metzger D
RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations.
Development (Cambridge, England) 2001;128(5):675-88.
2001: Abu-Abed S; Dollé P; Metzger D; Beckett B; Chambon P; Petkovich M
The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.
Genes & development 2001;15(2):226-40.
2001: Imai T; Jiang M; Chambon P; Metzger D
Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):224-8.
2000: Dilworth F J; Fromental-Ramain C; Yamamoto K; Chambon P
ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro.
Molecular cell 2000;6(5):1049-58.
2000: Chiba H; Chambon P; Metzger D
F9 embryonal carcinoma cells engineered for tamoxifen-dependent Cre-mediated site-directed mutagenesis and doxycycline-inducible gene expression.
Experimental cell research 2000;260(2):334-9.
2000: Li M; Indra A K; Warot X; Brocard J; Messaddeq N; Kato S; Metzger D; Chambon P
Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis.
Nature 2000;407(6804):633-6.
2000: Dupont S; Krust A; Gansmuller A; Dierich A; Chambon P; Mark M
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes.
Development (Cambridge, England) 2000;127(19):4277-91.
2000: Kopf E; Plassat J L; Vivat V; de Thé H; Chambon P; Rochette-Egly C
Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway.
The Journal of biological chemistry 2000;275(43):33280-8.
2000: Rochette-Egly C; Plassat J L; Taneja R; Chambon P
The AF-1 and AF-2 activating domains of retinoic acid receptor-alpha (RARalpha) and their phosphorylation are differentially involved in parietal endodermal differentiation of F9 cells and retinoid-induced expression of target genes.
Molecular endocrinology (Baltimore, Md.) 2000;14(9):1398-410.
2000: Benecke A; Chambon P; Gronemeyer H
Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.
EMBO reports 2000;1(2):151-7.
2000: Mollard R; Ghyselinck N B; Wendling O; Chambon P; Mark M
Stage-dependent responses of the developing lung to retinoic acid signaling.
The International journal of developmental biology 2000;44(5):457-62.
2000: Romand R; Sapin V; Ghyselinck N B; Avan P; Le Calvez S; Dollé P; Chambon P; Mark M
Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice.
The European journal of neuroscience 2000;12(8):2793-804.
2000: Cammas F; Garnier J; Chambon P; Losson R
Correlation of the exon/intron organization to the conserved domains of the mouse transcriptional corepressor TIF1beta.
Gene 2000;253(2):231-5.
2000: Plassat J; Penna L; Chambon P; Rochette-Egly C
The conserved amphipatic alpha-helical core motif of RARgamma and RARalpha activating domains is indispensable for RA-induced differentiation of F9 cells.
Journal of cell science 2000;113 ( Pt 16)():2887-95.
2000: Bourguet W; Andry V; Iltis C; Klaholz B; Potier N; Van Dorsselaer A; Chambon P; Gronemeyer H; Moras D
Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: purification, crystallization, and preliminary X-ray diffraction analysis.
Protein expression and purification 2000;19(2):284-8.
2000: Cammas F; Mark M; Dollé P; Dierich A; Chambon P; Losson R
Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development.
Development (Cambridge, England) 2000;127(13):2955-63.
2000: Bastien J; Adam-Stitah S; Riedl T; Egly J M; Chambon P; Rochette-Egly C
TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7.
The Journal of biological chemistry 2000;275(29):21896-904.
2000: Mollard R; Viville S; Ward S J; Décimo D; Chambon P; Dollé P
Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.
Mechanisms of development 2000;94(1-2):223-32.
2000: Egea P F; Mitschler A; Rochel N; Ruff M; Chambon P; Moras D
Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.
The EMBO journal 2000;19(11):2592-601.
2000: Sapin V; Bouillet P; Oulad-Abdelghani M; Dastugue B; Chambon P; Dollé P
Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation.
Mechanisms of development 2000;92(2):295-9.
2000: Wendling O; Dennefeld C; Chambon P; Mark M
Retinoid signaling is essential for patterning the endoderm of the third and fourth pharyngeal arches.
Development (Cambridge, England) 2000;127(8):1553-62.
2000: Bourguet W; Vivat V; Wurtz J M; Chambon P; Gronemeyer H; Moras D
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Molecular cell 2000;5(2):289-98.
2000: Imai T; Chambon P; Metzger D
Inducible site-specific somatic mutagenesis in mouse hepatocytes.
Genesis (New York, N.Y. : 2000) 2000;26(2):147-8.
2000: Subbarayan V; Mark M; Messadeq N; Rustin P; Chambon P; Kastner P
RXRalpha overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRalpha-null fetuses.
The Journal of clinical investigation 2000;105(3):387-94.
2000: Niederreither K; Vermot J; Schuhbaur B; Chambon P; Dollé P
Retinoic acid synthesis and hindbrain patterning in the mouse embryo.
Development (Cambridge, England) 2000;127(1):75-85.
2000: Indra A K; Li M; Brocard J; Warot X; Bornert J M; Gérard C; Messaddeq N; Chambon P; Metzger D
Targeted somatic mutagenesis in mouse epidermis.
Hormone research 2000;54(5-6):296-300.
1999: Nielsen A L; Ortiz J A; You J; Oulad-Abdelghani M; Khechumian R; Gansmuller A; Chambon P; Losson R
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.
The EMBO journal 1999;18(22):6385-95.
1999: Indra A K; Warot X; Brocard J; Bornert J M; Xiao J H; Chambon P; Metzger D
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases.
Nucleic acids research 1999;27(22):4324-7.
1999: Dupé V; Ghyselinck N B; Wendling O; Chambon P; Mark M
Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse.
Development (Cambridge, England) 1999;126(22):5051-9.
1999: Ghyselinck N B; Båvik C; Sapin V; Mark M; Bonnier D; Hindelang C; Dierich A; Nilsson C B; Håkansson H; Sauvant P; Azaïs-Braesco V; Frasson M; Picaud S; Chambon P
Cellular retinol-binding protein I is essential for vitamin A homeostasis.
The EMBO journal 1999;18(18):4903-14.
1999: Mark M; Ghyselinck N B; Wendling O; Dupé V; Mascrez B; Kastner P; Chambon P
A genetic dissection of the retinoid signalling pathway in the mouse.
The Proceedings of the Nutrition Society 1999;58(3):609-13.
1999: Géhin M; Vivat V; Wurtz J M; Losson R; Chambon P; Moras D; Gronemeyer H
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
Chemistry & biology 1999;6(8):519-29.
1999: Adam-Stitah S; Penna L; Chambon P; Rochette-Egly C
Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases.
The Journal of biological chemistry 1999;274(27):18932-41.
1999: Chazaud C; Chambon P; Dollé P
Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis.
Development (Cambridge, England) 1999;126(12):2589-96.
1999: Remboutsika E; Lutz Y; Gansmuller A; Vonesch J L; Losson R; Chambon P
The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin.
Journal of cell science 1999;112 ( Pt 11)():1671-83.
1999: Davenne M; Maconochie M K; Neun R; Pattyn A; Chambon P; Krumlauf R; Rijli F M
Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain.
Neuron 1999;22(4):677-91.
1999: Gaudon C; Chambon P; Losson R
Role of the essential yeast protein PSU1 in p6anscriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors.
The EMBO journal 1999;18(8):2229-40.
1999: Niederreither K; Subbarayan V; Dollé P; Chambon P
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development.
Nature genetics 1999;21(4):444-8.
1999: Dupé V; Ghyselinck N B; Thomazy V; Nagy L; Davies P J; Chambon P; Mark M
Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods.
Developmental biology 1999;208(1):30-43.
1999: Dilworth F J; Fromental-Ramain C; Remboutsika E; Benecke A; Chambon P
Ligand-dependent activation of transcription in vitro by retinoic acid receptor alpha/retinoid X receptor alpha heterodimers that mimics transactivation by retinoids in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):1995-2000.
1999: Venturini L; You J; Stadler M; Galien R; Lallemand V; Koken M H; Mattei M G; Ganser A; Chambon P; Losson R; de Thé H
TIF1gamma, a novel member of the transcriptional intermediary factor 1 family.
Oncogene 1999;18(5):1209-17.
1999: Wendling O; Chambon P; Mark M
Retinoid X receptors are essential for early mouse development and placentogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):547-51.
1999: Krezel W; Kastner P; Chambon P
Differential expression of retinoid receptors in the adult mouse central nervous system.
Neuroscience 1999;89(4):1291-300.
1998: Mascrez B; Mark M; Dierich A; Ghyselinck N B; Kastner P; Chambon P
The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.
Development (Cambridge, England) 1998;125(23):4691-707.
1998: Chambon P
Spatio-temporally-controlled somatic mutations in the mouse.
Pathologie-biologie 1998;46(9):671-3.
1998: Gaub M P; Lutz Y; Ghyselinck N B; Scheuer I; Pfister V; Chambon P; Rochette-Egly C
Nuclear detection of cellular retinoic acid binding proteins I and II with new antibodies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(10):1103-11.
1998: Barros A C; Erway L C; Krezel W; Curran T; Kastner P; Chambon P; Forrest D
Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.
Neuroreport 1998;9(13):2933-7.
1998: Niederreither K; Harbers M; Chambon P; Dollé P
Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis.
Oncogene 1998;17(12):1577-85.
1998: Brocard J; Feil R; Chambon P; Metzger D
A chimeric Cre recombinase inducible by synthetic,but not by natural ligands of the glucocorticoid receptor.
Nucleic acids research 1998;26(17):4086-90.
1998: Um S; Harbers M; Benecke A; Pierrat B; Losson R; Chambon P
Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase.
The Journal of biological chemistry 1998;273(33):20728-36.
1998: Ghyselinck N B; Wendling O; Messaddeq N; Dierich A; Lampron C; Décimo D; Viville S; Chambon P; Mark M
Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.
Developmental biology 1998;198(2):303-18.
1998: Fraser R A; Heard D J; Adam S; Lavigne A C; Le Douarin B; Tora L; Losson R; Rochette-Egly C; Chambon P
The putative cofactor TIF1alpha is a protein kinase that is hyperphosphorylated upon interaction with liganded nuclear receptors.
The Journal of biological chemistry 1998;273(26):16199-204.
1998: Huang N; vom Baur E; Garnier J M; Lerouge T; Vonesch J L; Lutz Y; Chambon P; Losson R
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators.
The EMBO journal 1998;17(12):3398-412.
1998: vom Baur E; Harbers M; Um S J; Benecke A; Chambon P; Losson R
The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors.
Genes & development 1998;12(9):1278-89.
1998: Le Douarin B; You J; Nielsen A L; Chambon P; Losson R
TIF1alpha: a possible link between KRAB zinc finger proteins and nuclear receptors.
The Journal of steroid biochemistry and molecular biology 1998;65(1-6):43-50.
1998: Klaholz B P; Renaud J P; Mitschler A; Zusi C; Chambon P; Gronemeyer H; Moras D
Conformational adaptation of agonists to the human nuclear receptor RAR gamma.
Nature structural biology 1998;5(3):199-202.
1998: Gavalas A; Studer M; Lumsden A; Rijli F M; Krumlauf R; Chambon P
Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch.
Development (Cambridge, England) 1998;125(6):1123-36.
1998: Studer M; Gavalas A; Marshall H; Ariza-McNaughton L; Rijli F M; Chambon P; Krumlauf R
Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning.
Development (Cambridge, England) 1998;125(6):1025-36.
1998: Krezel W; Ghyselinck N; Samad T A; Dupé V; Kastner P; Borrelli E; Chambon P
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.
Science (New York, N.Y.) 1998;279(5352):863-7.
1998: Mark M; Ghyselinck N B; Kastner P; Dupé V; Wendling O; Krezel W; Mascrez B; Chambon P
Mesectoderm is a major target of retinoic acid action.
European journal of oral sciences 1998;106 Suppl 1():24-31.
1998: Oulad-Abdelghani M; Chazaud C; Bouillet P; Mattei M G; Dollé P; Chambon P
Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.
The International journal of developmental biology 1998;42(1):23-32.
1998: Abu-Abed S S; Beckett B R; Chiba H; Chithalen J V; Jones G; Metzger D; Chambon P; Petkovich M
Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha.
The Journal of biological chemistry 1998;273(4):2409-15.
1998: Voegel J J; Heine M J; Tini M; Vivat V; Chambon P; Gronemeyer H
The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways.
The EMBO journal 1998;17(2):507-19.
1998: Rijli F M; Gavalas A; Chambon P
Segmentation and specification in the branchial region of the head: the role of the Hox selector genes.
The International journal of developmental biology 1998;42(3):393-401.
1997: Warot X; Fromental-Ramain C; Fraulob V; Chambon P; Dollé P
Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts.
Development (Cambridge, England) 1997;124(23):4781-91.
1997: Kastner P; Messaddeq N; Mark M; Wendling O; Grondona J M; Ward S; Ghyselinck N; Chambon P
Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.
Development (Cambridge, England) 1997;124(23):4749-58.
1997: Brocard J; Warot X; Wendling O; Messaddeq N; Vonesch J L; Chambon P; Metzger D
Spatio-temporally controlled site-specific somatic mutagenesis in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14559-63.
1997: Samad T A; Krezel W; Chambon P; Borrelli E
Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14349-54.
1997: Sapin V; Dollé P; Hindelang C; Kastner P; Chambon P
Defects of the chorioallantoic placenta in mouse RXRalpha null fetuses.
Developmental biology 1997;191(1):29-41.
1997: Taneja R; Rochette-Egly C; Plassat J L; Penna L; Gaub M P; Chambon P
Phosphorylation of activation functions AF-1 and AF-2 of RAR alpha and RAR gamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment.
The EMBO journal 1997;16(21):6452-65.
1997: Chiba H; Clifford J; Metzger D; Chambon P
Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.
The Journal of cell biology 1997;139(3):735-47.
1997: Mark M; Rijli F M; Chambon P
Homeobox genes in embryogenesis and pathogenesis.
Pediatric research 1997;42(4):421-9.
1997: Gavalas A; Davenne M; Lumsden A; Chambon P; Rijli F M
Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning.
Development (Cambridge, England) 1997;124(19):3693-702.
1997: Oulad-Abdelghani M; Chazaud C; Bouillet P; Sapin V; Chambon P; Dollé P
Meis2, a novel mouse Pbx-related homeobox gene induced by retinoic acid during differentiation of P19 embryonal carcinoma cells.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;210(2):173-83.
1997: Sumi-Ichinose C; Ichinose H; Metzger D; Chambon P
SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.
Molecular and cellular biology 1997;17(10):5976-86.
1997: Ward S J; Chambon P; Ong D E; Båvik C
A retinol-binding protein receptor-mediated mechanism for uptake of vitamin A to postimplantation rat embryos.
Biology of reproduction 1997;57(4):751-5.
1997: Vivat V; Zechel C; Wurtz J M; Bourguet W; Kagechika H; Umemiya H; Shudo K; Moras D; Gronemeyer H; Chambon P
A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers.
The EMBO journal 1997;16(18):5697-709.
1997: Subbarayan V; Kastner P; Mark M; Dierich A; Gorry P; Chambon P
Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.
Mechanisms of development 1997;66(1-2):131-42.
1997: Rijli F M; Chambon P
Genetic interactions of Hox genes in limb development: learning from compound mutants.
Current opinion in genetics & development 1997;7(4):481-7.
1997: Feil R; Wagner J; Metzger D; Chambon P
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains.
Biochemical and biophysical research communications 1997;237(3):752-7.
1997: Boudjelal M; Taneja R; Matsubara S; Bouillet P; Dolle P; Chambon P
Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells.
Genes & development 1997;11(16):2052-65.
1997: Rochette-Egly C; Adam S; Rossignol M; Egly J M; Chambon P
Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7.
Cell 1997;90(1):97-107.
1997: de Murcia J M; Niedergang C; Trucco C; Ricoul M; Dutrillaux B; Mark M; Oliver F J; Masson M; Dierich A; LeMeur M; Walztinger C; Chambon P; de Murcia G
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7303-7.
1997: Ghyselinck N B; Dupé V; Dierich A; Messaddeq N; Garnier J M; Rochette-Egly C; Chambon P; Mark M
Role of the retinoic acid receptor beta (RARbeta) during mouse development.
The International journal of developmental biology 1997;41(3):425-47.
1997: Mengus G; May M; Carré L; Chambon P; Davidson I
Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.
Genes & development 1997;11(11):1381-95.
1997: Chiba H; Clifford J; Metzger D; Chambon P
Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells.
Molecular and cellular biology 1997;17(6):3013-20.
1997: Bouillet P; Sapin V; Chazaud C; Messaddeq N; Décimo D; Dollé P; Chambon P
Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein.
Mechanisms of development 1997;63(2):173-86.
1997: Le Douarin B; Nielsen A L; You J; Chambon P; Losson R
TIF1 alpha: a chromatin-specific mediator for the ligand-dependent activation function AF-2 of nuclear receptors?
Biochemical Society transactions 1997;25(2):605-12.
1997: Umemiya H; Kagechika H; Fukasawa H; Kawachi E; Ebisawa M; Hashimoto Y; Eisenmann G; Erb C; Pornon A; Chambon P; Gronemeyer H; Shudo K
Action mechanism of retinoid-synergistic dibenzodiazepines.
Biochemical and biophysical research communications 1997;233(1):121-5.
1997: Ichinose H; Garnier J M; Chambon P; Losson R
Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.
Gene 1997;188(1):95-100.
1997: Fraser R A; Rossignol M; Heard D J; Egly J M; Chambon P
SUG1, a putative transcriptional mediator and subunit of the PA700 proteasome regulatory complex, is a DNA helicase.
The Journal of biological chemistry 1997;272(11):7122-6.
1997: Niederreither K; McCaffery P; Dräger U C; Chambon P; Dollé P
Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development.
Mechanisms of development 1997;62(1):67-78.
1997: Sapin V; Ward S J; Bronner S; Chambon P; Dollé P
Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(2):199-210.
1997: Dupé V; Davenne M; Brocard J; Dollé P; Mark M; Dierich A; Chambon P; Rijli F M
In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE).
Development (Cambridge, England) 1997;124(2):399-410.
1997: Kastner P; Mark M; Ghyselinck N; Krezel W; Dupé V; Grondona J M; Chambon P
Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.
Development (Cambridge, England) 1997;124(2):313-26.
1997: Rochel N; Renaud J P; Ruff M; Vivat V; Granger F; Bonnier D; Lerouge T; Chambon P; Gronemeyer H; Moras D
Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.
Biochemical and biophysical research communications 1997;230(2):293-6.
1997: Mark M; Kastner P; Ghyselinck N B; Krezel W; Dupé V; Chambon P
[Genetic control of the development by retinoic acid]
Comptes rendus des séances de la Société de biologie et de ses filiales 1997;191(1):77-90.
1996: Le Douarin B; Nielsen A L; Garnier J M; Ichinose H; Jeanmougin F; Losson R; Chambon P
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
The EMBO journal 1996;15(23):6701-15.
1996: Brocard J; Kastner P; Chambon P
Two novel RXR alpha isoforms from mouse testis.
Biochemical and biophysical research communications 1996;229(1):211-8.
1996: Fromental-Ramain C; Warot X; Messadecq N; LeMeur M; Dollé P; Chambon P
Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod.
Development (Cambridge, England) 1996;122(10):2997-3011.
1996: Oulad-Abdelghani M; Bouillet P; Décimo D; Gansmuller A; Heyberger S; Dollé P; Bronner S; Lutz Y; Chambon P
Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.
The Journal of cell biology 1996;135(2):469-77.
1996: Feil R; Brocard J; Mascrez B; LeMeur M; Metzger D; Chambon P
Ligand-activated site-specific recombination in mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10887-90.
1996: Lefebvre O; Chenard M P; Masson R; Linares J; Dierich A; LeMeur M; Wendling C; Tomasetto C; Chambon P; Rio M C
Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein.
Science (New York, N.Y.) 1996;274(5285):259-62.
1996: Bertolotti A; Lutz Y; Heard D J; Chambon P; Tora L
hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.
The EMBO journal 1996;15(18):5022-31.
1996: Nakshatri H; Bouillet P; Bhat-Nakshatri P; Chambon P
Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells.
Gene 1996;174(1):79-84.
1996: Bouillet P; Oulad-Abdelghani M; Ward S J; Bronner S; Chambon P; Dollé P
A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid.
Mechanisms of development 1996;58(1-2):141-52.
1996: Clifford J; Chiba H; Sobieszczuk D; Metzger D; Chambon P
RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids.
The EMBO journal 1996;15(16):4142-55.
1996: Taneja R; Thisse B; Rijli F M; Thisse C; Bouillet P; Dollé P; Chambon P
The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos.
Developmental biology 1996;177(2):397-412.
1996: Krezel W; Dupé V; Mark M; Dierich A; Kastner P; Chambon P
RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9010-4.
1996: Chen J Y; Clifford J; Zusi C; Starrett J; Tortolani D; Ostrowski J; Reczek P R; Chambon P; Gronemeyer H
Two distinct actions of retinoid-receptor ligands.
Nature 1996;382(6594):819-22.
1996: Lavigne A C; Mengus G; May M; Dubrovskaya V; Tora L; Chambon P; Davidson I
Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein.
The Journal of biological chemistry 1996;271(33):19774-80.
1996: Grondona J M; Kastner P; Gansmuller A; Décimo D; Chambon P; Mark M
Retinal dysplasia and degeneration in RARbeta2/RARgamma2 compound mutant mice.
Development (Cambridge, England) 1996;122(7):2173-88.
1996: Voegel J J; Heine M J; Zechel C; Chambon P; Gronemeyer H
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.
The EMBO journal 1996;15(14):3667-75.
1996: May M; Mengus G; Lavigne A C; Chambon P; Davidson I
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
The EMBO journal 1996;15(12):3093-104.
1996: Oulad-Abdelghani M; Bouillet P; Chazaud C; Dollé P; Chambon P
AP-2.2: a novel AP-2-related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells.
Experimental cell research 1996;225(2):338-47.
1996: Niederreither K; Ward S J; Dollé P; Chambon P
Morphological and molecular characterization of retinoic acid-induced limb duplications in mice.
Developmental biology 1996;176(2):185-98.
1996: Taneja R; Roy B; Plassat J L; Zusi C F; Ostrowski J; Reczek P R; Chambon P
Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):6197-202.
1996: Le Douarin B; vom Baur E; Zechel C; Heery D; Heine M; Vivat V; Gronemeyer H; Losson R; Chambon P
Ligand-dependent interaction of nuclear receptors with potential transcriptional intermediary factors (mediators).
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1339):569-78.
1996: Båvik C; Ward S J; Chambon P
Developmental abnormalities in cultured mouse embryos deprived of retinoic by inhibition of yolk-sac retinol binding protein synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3110-4.
1996: Fromental-Ramain C; Warot X; Lakkaraju S; Favier B; Haack H; Birling C; Dierich A; Doll e P; Chambon P
Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning.
Development (Cambridge, England) 1996;122(2):461-72.
1996: Favier B; Rijli F M; Fromental-Ramain C; Fraulob V; Chambon P; Dollé P
Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton.
Development (Cambridge, England) 1996;122(2):449-60.
1996: Wurtz J M; Bourguet W; Renaud J P; Vivat V; Chambon P; Moras D; Gronemeyer H
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(2):206.
1996: Chazaud C; Oulad-Abdelghani M; Bouillet P; Décimo D; Chambon P; Dollé P
AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis.
Mechanisms of development 1996;54(1):83-94.
1996: vom Baur E; Zechel C; Heery D; Heine M J; Garnier J M; Vivat V; Le Douarin B; Gronemeyer H; Chambon P; Losson R
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.
The EMBO journal 1996;15(1):110-24.
1996: Kastner P; Mark M; Leid M; Gansmuller A; Chin W; Grondona J M; Décimo D; Krezel W; Dierich A; Chambon P
Abnormal spermatogenesis in RXR beta mutant mice.
Genes & development 1996;10(1):80-92.
1996: Wurtz J M; Bourguet W; Renaud J P; Vivat V; Chambon P; Moras D; Gronemeyer H
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(1):87-94.
1995: Bouillet P; Chazaud C; Oulad-Abdelghani M; Dollé P; Chambon P
Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells.
Developmental dynamics : an official publication of the American Association of Anatomists 1995;204(4):372-82.
1995: Roy B; Taneja R; Chambon P
Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.
Molecular and cellular biology 1995;15(12):6481-7.
1995: Kastner P; Mark M; Chambon P
Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?
Cell 1995;83(6):859-69.
1995: Renaud J P; Rochel N; Ruff M; Vivat V; Chambon P; Gronemeyer H; Moras D
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid.
Nature 1995;378(6558):681-9.
1995: Bourguet W; Ruff M; Bonnier D; Granger F; Boeglin M; Chambon P; Moras D; Gronemeyer H
Purification, functional characterization, and crystallization of the ligand binding domain of the retinoid X receptor.
Protein expression and purification 1995;6(5):604-8.
1995: Scheer E; Mattei M G; Jacq X; Chambon P; Tora L
Organization and chromosomal localization of the gene (TAF2H) encoding the human TBP-associated factor II 30 (TAFII30).
Genomics 1995;29(1):269-72.
1995: Rijli F M; Matyas R; Pellegrini M; Dierich A; Gruss P; Dollé P; Chambon P
Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8185-9.
1995: Bouillet P; Oulad-Abdelghani M; Vicaire S; Garnier J M; Schuhbaur B; Dollé P; Chambon P
Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2).
Developmental biology 1995;170(2):420-33.
1995: Taneja R; Bouillet P; Boylan J F; Gaub M P; Roy B; Gudas L J; Chambon P
Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7854-8.
1995: Boam D S; Davidson I; Chambon P
A TATA-less promoter containing binding sites for ubiquitous transcription factors mediates cell type-specific regulation of the gene for transcription enhancer factor-1 (TEF-1).
The Journal of biological chemistry 1995;270(33):19487-94.
1995: Metzger D; Clifford J; Chiba H; Chambon P
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6991-5.
1995: Rochette-Egly C; Oulad-Abdelghani M; Staub A; Pfister V; Scheuer I; Chambon P; Gaub M P
Phosphorylation of the retinoic acid receptor-alpha by protein kinase A.
Molecular endocrinology (Baltimore, Md.) 1995;9(7):860-71.
1995: Bourguet W; Ruff M; Chambon P; Gronemeyer H; Moras D
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha.
Nature 1995;375(6530):377-82.
1995: Lohnes D; Mark M; Mendelsohn C; Dollé P; Decimo D; LeMeur M; Dierich A; Gorry P; Chambon P
Developmental roles of the retinoic acid receptors.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):475-86.
1995: Le Douarin B; Zechel C; Garnier J M; Lutz Y; Tora L; Pierrat P; Heery D; Gronemeyer H; Chambon P; Losson R
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.
The EMBO journal 1995;14(9):2020-33.
1995: Metzger D; Berry M; Ali S; Chambon P
Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo.
Molecular endocrinology (Baltimore, Md.) 1995;9(5):579-91.
1995: Lefebvre O; Régnier C; Chenard M P; Wendling C; Chambon P; Basset P; Rio M C
Developmental expression of mouse stromelysin-3 mRNA.
Development (Cambridge, England) 1995;121(4):947-55.
1995: Mengus G; May M; Jacq X; Staub A; Tora L; Chambon P; Davidson I
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.
The EMBO journal 1995;14(7):1520-31.
1995: Metzger D; Ali S; Bornert J M; Chambon P
Characterization of the amino-terminal transcriptional activation function of the human estrogen receptor in animal and yeast cells.
The Journal of biological chemistry 1995;270(16):9535-42.
1995: Chen J Y; Penco S; Ostrowski J; Balaguer P; Pons M; Starrett J E; Reczek P; Chambon P; Gronemeyer H
RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.
The EMBO journal 1995;14(6):1187-97.
1995: Okada A; Bellocq J P; Rouyer N; Chenard M P; Rio M C; Chambon P; Basset P
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2730-4.
1995: Le Douarin B; Pierrat B; vom Baur E; Chambon P; Losson R
A new version of the two-hybrid assay for detection of protein-protein interactions.
Nucleic acids research 1995;23(5):876-8.
1995: Boylan J F; Lufkin T; Achkar C C; Taneja R; Chambon P; Gudas L J
Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
Molecular and cellular biology 1995;15(2):843-51.
1995: Lampron C; Rochette-Egly C; Gorry P; Dollé P; Mark M; Lufkin T; LeMeur M; Chambon P
Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal.
Development (Cambridge, England) 1995;121(2):539-48.
1995: Mark M; Lohnes D; Mendelsohn C; Dupé V; Vonesch J L; Kastner P; Rijli F; Bloch-Zupan A; Chambon P
Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton.
The International journal of developmental biology 1995;39(1):111-21.
1995: Favier B; Le Meur M; Chambon P; Dollé P
Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):310-4.
1995: Chambon P
The molecular and genetic dissection of the retinoid signaling pathway.
Recent progress in hormone research 1995;50():317-32.
1994: Rijli F M; Dollé P; Fraulob V; LeMeur M; Chambon P
Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;201(4):366-77.
1994: Mendelsohn C; Mark M; Dollé P; Dierich A; Gaub M P; Krust A; Lampron C; Chambon P
Retinoic acid receptor beta 2 (RAR beta 2) null mutant mice appear normal.
Developmental biology 1994;166(1):246-58.
1994: Durand B; Saunders M; Gaudon C; Roy B; Losson R; Chambon P
Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.
The EMBO journal 1994;13(22):5370-82.
1994: Rochette-Egly C; Lutz Y; Pfister V; Heyberger S; Scheuer I; Chambon P; Gaub M P
Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.
Biochemical and biophysical research communications 1994;204(2):525-36.
1994: Chen Z P; Shemshedini L; Durand B; Noy N; Chambon P; Gronemeyer H
Pure and functionally homogeneous recombinant retinoid X receptor.
The Journal of biological chemistry 1994;269(41):25770-6.
1994: Jacq X; Brou C; Lutz Y; Davidson I; Chambon P; Tora L
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor.
Cell 1994;79(1):107-17.
1994: Mendelsohn C; Lohnes D; Décimo D; Lufkin T; LeMeur M; Chambon P; Mark M
Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.
Development (Cambridge, England) 1994;120(10):2749-71.
1994: Lohnes D; Mark M; Mendelsohn C; Dollé P; Dierich A; Gorry P; Gansmuller A; Chambon P
Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.
Development (Cambridge, England) 1994;120(10):2723-48.
1994: Gorry P; Lufkin T; Dierich A; Rochette-Egly C; Décimo D; Dollé P; Mark M; Durand B; Chambon P
The cellular retinoic acid binding protein I is dispensable.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9032-6.
1994: Kastner P; Grondona J M; Mark M; Gansmuller A; LeMeur M; Decimo D; Vonesch J L; Dollé P; Chambon P
Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.
Cell 1994;78(6):987-1003.
1994: Chaudhary S; Brou C; Valentin M E; Burton N; Tora L; Chambon P; Davidson I
A cell-specific factor represses stimulation of transcription in vitro by transcriptional enhancer factor 1.
Molecular and cellular biology 1994;14(8):5290-9.
1994: Basset P; Wolf C; Rouyer N; Bellocq J P; Rio M C; Chambon P
Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior.
Cancer 1994;74(3 Suppl):1045-9.
1994: Pierrat B; Heery D M; Chambon P; Losson R
A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast.
Gene 1994;143(2):193-200.
1994: Chambon P
The retinoid signaling pathway: molecular and genetic analyses.
Seminars in cell biology 1994;5(2):115-25.
1994: Heery D M; Pierrat B; Gronemeyer H; Chambon P; Losson R
Homo- and heterodimers of the retinoid X receptor (RXR) activated transcription in yeast.
Nucleic acids research 1994;22(5):726-31.
1994: Zechel C; Shen X Q; Chen J Y; Chen Z P; Chambon P; Gronemeyer H
The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.
The EMBO journal 1994;13(6):1425-33.
1994: Zechel C; Shen X Q; Chambon P; Gronemeyer H
Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements.
The EMBO journal 1994;13(6):1414-24.
1994: Vonesch J L; Nakshatri H; Philippe M; Chambon P; Dollé P
Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;199(3):199-213.
1994: Mendelsohn C; Larkin S; Mark M; LeMeur M; Clifford J; Zelent A; Chambon P
RAR beta isoforms: distinct transcriptional control by retinoic acid and specific spatial patterns of promoter activity during mouse embryonic development.
Mechanisms of development 1994;45(3):227-41.
1994: Lescure A; Lutz Y; Eberhard D; Jacq X; Krol A; Grummt I; Davidson I; Chambon P; Tora L
The N-terminal domain of the human TATA-binding protein plays a role in transcription from TATA-containing RNA polymerase II and III promoters.
The EMBO journal 1994;13(5):1166-75.
1994: Dollé P; Fraulob V; Kastner P; Chambon P
Developmental expression of murine retinoid X receptor (RXR) genes.
Mechanisms of development 1994;45(2):91-104.
1994: Nakshatri H; Chambon P
The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers.
The Journal of biological chemistry 1994;269(2):890-902.
1994: Rouyer N; Wolf C; Chenard M P; Rio M C; Chambon P; Bellocq J P; Basset P
Stromelysin-3 gene expression in human cancer: an overview.
Invasion & metastasis 1994;14(1-6):269-75.
1993: Chambon P
The molecular and genetic dissection of the retinoid signalling pathway.
Gene 1993;135(1-2):223-8.
1993: Mader S; Chen J Y; Chen Z; White J; Chambon P; Gronemeyer H
The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.
The EMBO journal 1993;12(13):5029-41.
1993: Rijli F M; Mark M; Lakkaraju S; Dierich A; Dollé P; Chambon P
A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene.
Cell 1993;75(7):1333-49.
1993: Dollé P; Dierich A; LeMeur M; Schimmang T; Schuhbaur B; Chambon P; Duboule D
Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs.
Cell 1993;75(3):431-41.
1993: Mark M; Lufkin T; Vonesch J L; Ruberte E; Olivo J C; Dollé P; Gorry P; Lumsden A; Chambon P
Two rhombomeres are altered in Hoxa-1 mutant mice.
Development (Cambridge, England) 1993;119(2):319-38.
1993: Boylan J F; Lohnes D; Taneja R; Chambon P; Gudas L J
Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9601-5.
1993: Rasmussen U B; Wolf C; Mattei M G; Chenard M P; Bellocq J P; Chambon P; Rio M C; Basset P
Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma.
Cancer research 1993;53(17):4096-101.
1993: Mark M; Lufkin T; Dollé P; Dierich A; LeMeur M; Chambon P
Roles of Hox genes: what we have learnt from gain of function and loss of function mutations in the mouse.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1993;316(9):995-1008.
1993: Lufkin T; Lohnes D; Mark M; Dierich A; Gorry P; Gaub M P; LeMeur M; Chambon P
High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7225-9.
1993: Perez A; Kastner P; Sethi S; Lutz Y; Reibel C; Chambon P
PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.
The EMBO journal 1993;12(8):3171-82.
1993: Dollé P; Lufkin T; Krumlauf R; Mark M; Duboule D; Chambon P
Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7666-70.
1993: Murphy G; Segain J P; O'Shea M; Cockett M; Ioannou C; Lefebvre O; Chambon P; Basset P
The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase.
The Journal of biological chemistry 1993;268(21):15435-41.
1993: Lefebvre O; Wolf C; Kédinger M; Chenard M P; Tomasetto C; Chambon P; Rio M C
The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression.
The Journal of cell biology 1993;122(1):191-8.
1993: Nagpal S; Friant S; Nakshatri H; Chambon P
RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.
The EMBO journal 1993;12(6):2349-60.
1993: Hwang J J; Chambon P; Davidson I
Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1.
The EMBO journal 1993;12(6):2337-48.
1993: Ruberte E; Friederich V; Chambon P; Morriss-Kay G
Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development.
Development (Cambridge, England) 1993;118(1):267-82.
1993: Lohnes D; Kastner P; Dierich A; Mark M; LeMeur M; Chambon P
Function of retinoic acid receptor gamma in the mouse.
Cell 1993;73(4):643-58.
1993: Heery D M; Zacharewski T; Pierrat B; Gronemeyer H; Chambon P; Losson R
Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4281-5.
1993: Bocquel M T; Ji J; Ylikomi T; Benhamou B; Vergezac A; Chambon P; Gronemeyer H
Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerization.
The Journal of steroid biochemistry and molecular biology 1993;45(4):205-15.
1993: Schaeffer L; Roy R; Humbert S; Moncollin V; Vermeulen W; Hoeijmakers J H; Chambon P; Egly J M
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor.
Science (New York, N.Y.) 1993;260(5104):58-63.
1993: Ali S; Metzger D; Bornert J M; Chambon P
Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.
The EMBO journal 1993;12(3):1153-60.
1993: Wolf C; Rouyer N; Lutz Y; Adida C; Loriot M; Bellocq J P; Chambon P; Basset P
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1843-7.
1993: Mader S; Chambon P; White J H
Defining a minimal estrogen receptor DNA binding domain.
Nucleic acids research 1993;21(5):1125-32.
1993: Brou C; Chaudhary S; Davidson I; Lutz Y; Wu J; Egly J M; Tora L; Chambon P
Distinct TFIID complexes mediate the effect of different transcriptional activators.
The EMBO journal 1993;12(2):489-99.
1993: Brou C; Wu J; Ali S; Scheer E; Lang C; Davidson I; Chambon P; Tora L
Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor.
Nucleic acids research 1993;21(1):5-12.
1993: Gilbert D M; Heery D M; Losson R; Chambon P; Lemoine Y
Estradiol-inducible squelching and cell growth arrest by a chimeric VP16-estrogen receptor expressed in Saccharomyces cerevisiae: suppression by an allele of PDR1.
Molecular and cellular biology 1993;13(1):462-72.
1993: Allenby G; Bocquel M T; Saunders M; Kazmer S; Speck J; Rosenberger M; Lovey A; Kastner P; Grippo J F; Chambon P
Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):30-4.
1993: Mader S; Leroy P; Chen J Y; Chambon P
Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors.
The Journal of biological chemistry 1993;268(1):591-600.
1992: Wolf C; Chenard M P; Durand de Grossouvre P; Bellocq J P; Chambon P; Basset P
Breast-cancer-associated stromelysin-3 gene is expressed in basal cell carcinoma and during cutaneous wound healing.
The Journal of investigative dermatology 1992;99(6):870-2.
1992: Garcia T; Benhamou B; Gofflo D; Vergezac A; Philibert D; Chambon P; Gronemeyer H
Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2071-8.
1992: Rochette-Egly C; Gaub M P; Lutz Y; Ali S; Scheuer I; Chambon P
Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2197-209.
1992: Lufkin T; Mark M; Hart C P; Dollé P; LeMeur M; Chambon P
Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene.
Nature 1992;359(6398):835-41.
1992: Leid M; Kastner P; Chambon P
Multiplicity generates diversity in the retinoic acid signalling pathways.
Trends in biochemical sciences 1992;17(10):427-33.
1992: Ylikomi T; Bocquel M T; Berry M; Gronemeyer H; Chambon P
Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors.
The EMBO journal 1992;11(10):3681-94.
1992: Durand B; Saunders M; Leroy P; Leid M; Chambon P
All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs.
Cell 1992;71(1):73-85.
1992: Fischer L; Gerard M; Chalut C; Lutz Y; Humbert S; Kanno M; Chambon P; Egly J M
Cloning of the 62-kilodalton component of basic transcription factor BTF2.
Science (New York, N.Y.) 1992;257(5075):1392-5.
1992: Chambon P; Courtney M; Kourilsky P; Lathe R
In memoriam. Jean-Pierre Lecocq, 1947-1992.
Gene 1992;118(1):1-4.
1992: Gilbert D M; Losson R; Chambon P
Ligand dependence of estrogen receptor induced changes in chromatin structure.
Nucleic acids research 1992;20(17):4525-31.
1992: Nagpal S; Saunders M; Kastner P; Durand B; Nakshatri H; Chambon P
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors.
Cell 1992;70(6):1007-19.
1992: Ruberte E; Friederich V; Morriss-Kay G; Chambon P
Differential distribution patterns of CRABP I and CRABP II transcripts during mouse embryogenesis.
Development (Cambridge, England) 1992;115(4):973-87.
1992: Gaub M P; Rochette-Egly C; Lutz Y; Ali S; Matthes H; Scheuer I; Chambon P
Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation.
Experimental cell research 1992;201(2):335-46.
1992: Mendelsohn C; Ruberte E; Chambon P
Retinoid receptors in vertebrate limb development.
Developmental biology 1992;152(1):50-61.
1992: Metzger D; Losson R; Bornert J M; Lemoine Y; Chambon P
Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast.
Nucleic acids research 1992;20(11):2813-7.
1992: White J; Brou C; Wu J; Lutz Y; Moncollin V; Chambon P
The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes.
The EMBO journal 1992;11(6):2229-40.
1992: Nagpal S; Zelent A; Chambon P
RAR-beta 4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiator codon.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2718-22.
1992: Kastner P; Perez A; Lutz Y; Rochette-Egly C; Gaub M P; Durand B; Lanotte M; Berger R; Chambon P
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.
The EMBO journal 1992;11(2):629-42.
1992: Shemshedini L; Ji J W; Brou C; Chambon P; Gronemeyer H
In vitro activity of the transcription activation functions of the progesterone receptor. Evidence for intermediary factors.
The Journal of biological chemistry 1992;267(3):1834-9.
1992: Moncollin V; Fischer L; Cavallini B; Egly J M; Chambon P
Class II (B) general transcription factor (TFIIB) that binds to the template-committed preinitiation complex is different from general transcription factor BTF3.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):397-401.
1992: Benhamou B; Garcia T; Lerouge T; Vergezac A; Gofflo D; Bigogne C; Chambon P; Gronemeyer H
A single amino acid that determines the sensitivity of progesterone receptors to RU486.
Science (New York, N.Y.) 1992;255(5041):206-9.
1992: Lohnes D; Dierich A; Ghyselinck N; Kastner P; Lampron C; LeMeur M; Lufkin T; Mendelsohn C; Nakshatri H; Chambon P
Retinoid receptors and binding proteins.
Journal of cell science. Supplement 1992;16():69-76.
1991: Gerard M; Fischer L; Moncollin V; Chipoulet J M; Chambon P; Egly J M
Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.
The Journal of biological chemistry 1991;266(31):20940-5.
1991: Mendelsohn C; Ruberte E; LeMeur M; Morriss-Kay G; Chambon P
Developmental analysis of the retinoic acid-inducible RAR-beta 2 promoter in transgenic animals.
Development (Cambridge, England) 1991;113(3):723-34.
1991: Leroy P; Nakshatri H; Chambon P
Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10138-42.
1991: Rochette-Egly C; Lutz Y; Saunders M; Scheuer I; Gaub M P; Chambon P
Retinoic acid receptor gamma: specific immunodetection and phosphorylation.
The Journal of cell biology 1991;115(2):535-45.
1991: Hareuveni M; Wreschner D H; Kieny M P; Dott K; Gautier C; Tomasetto C; Keydar I; Chambon P; Lathe R
Vaccinia recombinants expressing secreted and transmembrane forms of breast cancer-associated epithelial tumour antigen (ETA).
Vaccine 1991;9(9):618-26.
1991: White J H; Brou C; Wu J; Burton N; Egly J M; Chambon P
Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7674-8.
1991: Lufkin T; Dierich A; LeMeur M; Mark M; Chambon P
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression.
Cell 1991;66(6):1105-19.
1991: Hu L; Crowe D L; Rheinwald J G; Chambon P; Gudas L J
Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell carcinoma cell lines.
Cancer research 1991;51(15):3972-81.
1991: Smith W C; Nakshatri H; Leroy P; Rees J; Chambon P
A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter.
The EMBO journal 1991;10(8):2223-30.
1991: Xiao J H; Davidson I; Matthes H; Garnier J M; Chambon P
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1.
Cell 1991;65(4):551-68.
1991: Vasios G; Mader S; Gold J D; Leid M; Lutz Y; Gaub M P; Chambon P; Gudas L
The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element.
The EMBO journal 1991;10(5):1149-58.
1991: Turcotte B; Meyer M E; Bellard M; Dretzen G; Gronemeyer H; Chambon P
Control of transcription of the chicken progesterone receptor gene. In vitro and in vivo studies.
The Journal of biological chemistry 1991;266(4):2582-9.
1991: Schwartz L H; Koerner F C; Edgerton S M; Sawicka J M; Rio M C; Bellocq J P; Chambon P; Thor A D
pS2 expression and response to hormonal therapy in patients with advanced breast cancer.
Cancer research 1991;51(2):624-8.
1991: Ruberte E; Dolle P; Chambon P; Morriss-Kay G
Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos.
Development (Cambridge, England) 1991;111(1):45-60.
1991: Zelent A; Mendelsohn C; Kastner P; Krust A; Garnier J M; Ruffenach F; Leroy P; Chambon P
Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.
The EMBO journal 1991;10(1):71-81.
1991: Leroy P; Krust A; Zelent A; Mendelsohn C; Garnier J M; Kastner P; Dierich A; Chambon P
Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.
The EMBO journal 1991;10(1):59-69.
1991: Gronemeyer H; Meyer M E; Bocquel M T; Kastner P; Turcotte B; Chambon P
Progestin receptors: isoforms and antihormone action.
The Journal of steroid biochemistry and molecular biology 1991;40(1-3):271-8.
1991: Kastner P; Perez A; Lutz Y; Rochette-Egly C; Gaub M P; Chambon P
[Fusion proteins between PML and alpha-RAR in acute promyelocytic leukemia]
Comptes rendus des séances de la Société de biologie et de ses filiales 1991;185(6):391-401.
1990: Hareuveni M; Gautier C; Kieny M P; Wreschner D; Chambon P; Lathe R
Vaccination against tumor cells expressing breast cancer epithelial tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9498-502.
1990: Meyer M E; Pornon A; Ji J W; Bocquel M T; Chambon P; Gronemeyer H
Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.
The EMBO journal 1990;9(12):3923-32.
1990: Nicholson R C; Mader S; Nagpal S; Leid M; Rochette-Egly C; Chambon P
Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.
The EMBO journal 1990;9(13):4443-54.
1990: Brand N J; Petkovich M; Chambon P
Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha).
Nucleic acids research 1990;18(23):6799-806.
1990: Gaub M P; Bellard M; Scheuer I; Chambon P; Sassone-Corsi P
Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex.
Cell 1990;63(6):1267-76.
1990: Dollé P; Ruberte E; Leroy P; Morriss-Kay G; Chambon P
Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis.
Development (Cambridge, England) 1990;110(4):1133-51.
1990: Basset P; Bellocq J P; Wolf C; Stoll I; Hutin P; Limacher J M; Podhajcer O L; Chenard M P; Rio M C; Chambon P
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas.
Nature 1990;348(6303):699-704.
1990: Tasset D; Tora L; Fromental C; Scheer E; Chambon P
Distinct classes of transcriptional activating domains function by different mechanisms.
Cell 1990;62(6):1177-87.
1990: Berry M; Metzger D; Chambon P
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.
The EMBO journal 1990;9(9):2811-8.
1990: Turcotte B; Meyer M E; Bocquel M T; Bélanger L; Chambon P
Repression of the alpha-fetoprotein gene promoter by progesterone and chimeric receptors in the presence of hormones and antihormones.
Molecular and cellular biology 1990;10(9):5002-6.
1990: Kastner P; Bocquel M T; Turcotte B; Garnier J M; Horwitz K B; Chambon P; Gronemeyer H
Transient expression of human and chicken progesterone receptors does not support alternative translational initiation from a single mRNA as the mechanism generating two receptor isoforms.
The Journal of biological chemistry 1990;265(21):12163-7.
1990: Ponglikitmongkol M; White J H; Chambon P
Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements.
The EMBO journal 1990;9(7):2221-31.
1990: Kastner P; Krust A; Turcotte B; Stropp U; Tora L; Gronemeyer H; Chambon P
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.
The EMBO journal 1990;9(5):1603-14.
1990: Zheng X M; Black D; Chambon P; Egly J M
Sequencing and expression of complementary DNA for the general transcription factor BTF3.
Nature 1990;344(6266):556-9.
1990: Kastner P; Krust A; Mendelsohn C; Garnier J M; Zelent A; Leroy P; Staub A; Chambon P
Murine isoforms of retinoic acid receptor gamma with specific patterns of expression.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2700-4.
1990: Jeltsch J M; Turcotte B; Garnier J M; Lerouge T; Krozowski Z; Gronemeyer H; Chambon P
Characterization of multiple mRNAs originating from the chicken progesterone receptor gene. Evidence for a specific transcript encoding form A.
The Journal of biological chemistry 1990;265(7):3967-74.
1990: Tomasetto C; Rio M C; Gautier C; Wolf C; Hareuveni M; Chambon P; Lathe R
hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma.
The EMBO journal 1990;9(2):407-14.
1990: Ruberte E; Dolle P; Krust A; Zelent A; Morriss-Kay G; Chambon P
Specific spatial and temporal distribution of retinoic acid receptor gamma transcripts during mouse embryogenesis.
Development (Cambridge, England) 1990;108(2):213-22.
1990: Mullick A; Chambon P
Characterization of the estrogen receptor in two antiestrogen-resistant cell lines, LY2 and T47D.
Cancer research 1990;50(2):333-8.
1990: Rochette-Egly C; Fromental C; Chambon P
General repression of enhanson activity by the adenovirus-2 E1A proteins.
Genes & development 1990;4(1):137-50.
1989: Cavallini B; Faus I; Matthes H; Chipoulet J M; Winsor B; Egly J M; Chambon P
Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9803-7.
1989: Vasios G W; Gold J D; Petkovich M; Chambon P; Gudas L J
A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9099-103.
1989: Dollé P; Ruberte E; Kastner P; Petkovich M; Stoner C M; Gudas L J; Chambon P
Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.
Nature 1989;342(6250):702-5.
1989: Macchi M; Bornert J M; Davidson I; Kanno M; Rosales R; Vigneron M; Xiao J H; Fromental C; Chambon P
The SV40 TC-II(kappa B) enhanson binds ubiquitous and cell type specifically inducible nuclear proteins from lymphoid and non-lymphoid cell lines.
The EMBO journal 1989;8(13):4215-27.
1989: Kanno M; Fromental C; Staub A; Ruffenach F; Davidson I; Chambon P
The SV40 TC-II(kappa B) and the related H-2Kb enhansons exhibit different cell type specific and inducible proto-enhancer activities, but the SV40 core sequence and the AP-2 binding site have no enhanson properties.
The EMBO journal 1989;8(13):4205-14.
1989: Tora L; White J; Brou C; Tasset D; Webster N; Scheer E; Chambon P
The human estrogen receptor has two independent nonacidic transcriptional activation functions.
Cell 1989;59(3):477-87.
1989: Lennard A C; Matthes H W; Egly J M; Chambon P
Stereospecific relationships between elements in an SV40/adenovirus-2 heterologous promoter.
Nucleic acids research 1989;17(17):6903-14.
1989: Tora L; Mullick A; Metzger D; Ponglikitmongkol M; Park I; Chambon P
The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.
The EMBO journal 1989;8(7):1981-6.
1989: Hashimoto Y; Petkovich M; Gaub M P; Kagechika H; Shudo K; Chambon P
The retinoic acid receptors alpha and beta are expressed in the human promyelocytic leukemia cell line HL-60.
Molecular endocrinology (Baltimore, Md.) 1989;3(7):1046-52.
1989: Krust A; Kastner P; Petkovich M; Zelent A; Chambon P
A third human retinoic acid receptor, hRAR-gamma.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5310-4.
1989: Zelent A; Krust A; Petkovich M; Kastner P; Chambon P
Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.
Nature 1989;339(6227):714-7.
1989: Webster N J; Green S; Tasset D; Ponglikitmongkol M; Chambon P
The transcriptional activation function located in the hormone-binding domain of the human oestrogen receptor is not encoded in a single exon.
The EMBO journal 1989;8(5):1441-6.
1989: Meyer M E; Gronemeyer H; Turcotte B; Bocquel M T; Tasset D; Chambon P
Steroid hormone receptors compete for factors that mediate their enhancer function.
Cell 1989;57(3):433-42.
1989: Gaub M P; Lutz Y; Ruberte E; Petkovich M; Brand N; Chambon P
Antibodies specific to the retinoic acid human nuclear receptors alpha and beta.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3089-93.
1989: Bocquel M T; Kumar V; Stricker C; Chambon P; Gronemeyer H
The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific.
Nucleic acids research 1989;17(7):2581-95.
1989: Green S; Chambon P
Chimeric receptors used to probe the DNA-binding domain of the estrogen and glucocorticoid receptors.
Cancer research 1989;49(8 Suppl):2282s-2285s.
1989: Mader S; Kumar V; de Verneuil H; Chambon P
Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element.
Nature 1989;338(6212):271-4.
1989: Nunez A M; Berry M; Imler J L; Chambon P
The 5' flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein.
The EMBO journal 1989;8(3):823-9.
1989: Berry M; Nunez A M; Chambon P
Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(4):1218-22.
1989: Eul J; Meyer M E; Tora L; Bocquel M T; Quirin-Stricker C; Chambon P; Gronemeyer H
Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli.
The EMBO journal 1989;8(1):83-90.
1988: Tora L; Gaub M P; Mader S; Dierich A; Bellard M; Chambon P
Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter.
The EMBO journal 1988;7(12):3771-8.
1988: Mattei M G; Petkovich M; Mattei J F; Brand N; Chambon P
Mapping of the human retinoic acid receptor to the q21 band of chromosome 17.
Human genetics 1988;80(2):186-8.
1988: Fromental C; Kanno M; Nomiyama H; Chambon P
Cooperativity and hierarchical levels of functional organization in the SV40 enhancer.
Cell 1988;54(7):943-53.
1988: Davidson I; Xiao J H; Rosales R; Staub A; Chambon P
The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence.
Cell 1988;54(7):931-42.
1988: Webster N J; Green S; Jin J R; Chambon P
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function.
Cell 1988;54(2):199-207.
1988: Cavallini B; Huet J; Plassat J L; Sentenac A; Egly J M; Chambon P
A yeast activity can substitute for the HeLa cell TATA box factor.
Nature 1988;334(6177):77-80.
1988: Metzger D; White J H; Chambon P
The human oestrogen receptor functions in yeast.
Nature 1988;334(6177):31-6.
1988: Rio M C; Bellocq J P; Gairard B; Koehl C; Renaud R; Chambon P
[Specific expression of human pS2 gene in breast cancer]
Biochimie 1988;70(7):961-8.
1988: Arveiler B; Petkovich M; Mandel J L; Chambon P
A PstI RFLP for the human retinoic acid receptor in 17q21.
Nucleic acids research 1988;16(13):6252.
1988: Tora L; Gronemeyer H; Turcotte B; Gaub M P; Chambon P
The N-terminal region of the chicken progesterone receptor specifies target gene activation.
Nature 1988;333(6169):185-8.
1988: Brand N; Petkovich M; Krust A; Chambon P; de Thé H; Marchio A; Tiollais P; Dejean A
Identification of a second human retinoic acid receptor.
Nature 1988;332(6167):850-3.
1988: Mattei M G; Krust A; Stropp U; Mattei J F; Chambon P
Assignment of the human progesterone receptor to the q22 band of chromosome 11.
Human genetics 1988;78(1):96-7.
1988: Webster N; Jin J R; Green S; Hollis M; Chambon P
The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator.
Cell 1988;52(2):169-78.
1987: Kumar V; Green S; Stack G; Berry M; Jin J R; Chambon P
Functional domains of the human estrogen receptor.
Cell 1987;51(6):941-51.
1987: Gronemeyer H; Turcotte B; Quirin-Stricker C; Bocquel M T; Meyer M E; Krozowski Z; Jeltsch J M; Lerouge T; Garnier J M; Chambon P
The chicken progesterone receptor: sequence, expression and functional analysis.
The EMBO journal 1987;6(13):3985-94.
1987: Rio M C; Bellocq J P; Gairard B; Rasmussen U B; Krust A; Koehl C; Calderoli H; Schiff V; Renaud R; Chambon P
Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9243-7.
1987: Petkovich M; Brand N J; Krust A; Chambon P
A human retinoic acid receptor which belongs to the family of nuclear receptors.
Nature 1987;330(6147):444-50.
1987: Nomiyama H; Fromental C; Xiao J H; Chambon P
Cell-specific activity of the constituent elements of the simian virus 40 enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):7881-5.
1987: Xiao J H; Davidson I; Macchi M; Rosales R; Vigneron M; Staub A; Chambon P
In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer.
Genes & development 1987;1(8):794-807.
1987: Rosales R; Vigneron M; Macchi M; Davidson I; Xiao J H; Chambon P
In vitro binding of cell-specific and ubiquitous nuclear proteins to the octamer motif of the SV40 enhancer and related motifs present in other promoters and enhancers.
The EMBO journal 1987;6(10):3015-25.
1987: Xiao J H; Davidson I; Ferrandon D; Rosales R; Vigneron M; Macchi M; Ruffenach F; Chambon P
One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer.
The EMBO journal 1987;6(10):3005-13.
1987: Gaub M P; Dierich A; Astinotti D; Touitou I; Chambon P
The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.
The EMBO journal 1987;6(8):2313-20.
1987: Dierich A; Gaub M P; LePennec J P; Astinotti D; Chambon P
Cell-specificity of the chicken ovalbumin and conalbumin promoters.
The EMBO journal 1987;6(8):2305-12.
1987: Zheng X M; Moncollin V; Egly J M; Chambon P
A general transcription factor forms a stable complex with RNA polymerase B (II).
Cell 1987;50(3):361-8.
1987: Matthes H W; Staub A; Chambon P
The segmented paper method: DNA synthesis and mutagenesis by rapid microscale "shotgun gene synthesis".
Methods in enzymology 1987;154():250-87.
1986: Davidson I; Fromental C; Augereau P; Wildeman A; Zenke M; Chambon P
Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts.
Nature 1986;323(6088):544-8.
1986: Jeltsch J M; Krozowski Z; Quirin-Stricker C; Gronemeyer H; Simpson R J; Garnier J M; Krust A; Jacob F; Chambon P
Cloning of the chicken progesterone receptor.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5424-8.
1986: Wildeman A G; Zenke M; Schatz C; Wintzerith M; Grundström T; Matthes H; Takahashi K; Chambon P
Specific protein binding to the simian virus 40 enhancer in vitro.
Molecular and cellular biology 1986;6(6):2098-105.
1986: Zenke M; Grundström T; Matthes H; Wintzerith M; Schatz C; Wildeman A; Chambon P
Multiple sequence motifs are involved in SV40 enhancer function.
The EMBO journal 1986;5(2):387-97.
1986: Takahashi K; Vigneron M; Matthes H; Wildeman A; Zenke M; Chambon P
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter.
Nature 1986;319(6049):121-6.
1985: Miyamoto N G; Moncollin V; Egly J M; Chambon P
Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter.
The EMBO journal 1985;4(13A):3563-70.
1985: Barrera-Saldana H; Takahashi K; Vigneron M; Wildeman A; Davidson I; Chambon P
All six GC-motifs of the SV40 early upstream element contribute to promoter activity in vivo and in vitro.
The EMBO journal 1985;4(13B):3839-49.
1985: Grundström T; Zenke W M; Wintzerith M; Matthes H W; Staub A; Chambon P
Oligonucleotide-directed mutagenesis by microscale 'shot-gun' gene synthesis.
Nucleic acids research 1985;13(9):3305-16.
1984: Wildeman A G; Sassone-Corsi P; Grundström T; Zenke M; Chambon P
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor.
The EMBO journal 1984;3(13):3129-33.
1984: Miyamoto N G; Moncollin V; Wintzerith M; Hen R; Egly J M; Chambon P
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor.
Nucleic acids research 1984;12(23):8779-99.
1984: Egly J M; Miyamoto N G; Moncollin V; Chambon P
Is actin a transcription initiation factor for RNA polymerase B?
The EMBO journal 1984;3(10):2363-71.
1984: Vigneron M; Barrera-Saldana H A; Baty D; Everett R E; Chambon P
Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters.
The EMBO journal 1984;3(10):2373-82.
1984: Baty D; Barrera-Saldana H A; Everett R D; Vigneron M; Chambon P
Mutational dissection of the 21 bp repeat region of the SV40 early promoter reveals that it contains overlapping elements of the early-early and late-early promoters.
Nucleic acids research 1984;12(2):915-32.
1983: Wasylyk B; Wasylyk C; Matthes H; Wintzerith M; Chambon P
Transcription from the SV40 early-early and late-early overlapping promoters in the absence of DNA replication.
The EMBO journal 1983;2(9):1605-11.

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