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Hunter Champion

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Hunter C Champion
When to initiate intravenous therapy and/or refer.
M Patricia George; Mark T Gladwin; Siobhan Guyach; Christopher Janssen; Heather M Kling; Alison Morris; Jessica Murphy; Alexandra Brower; Jonathan P Carney; Hunter C Champion; Marc Simon; Rebecca Tarantelli; Karen A Norris
Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension.
Jayan Nagendran; Ian Paterson; Ivan M Rebeyka; David B Ross; Gopinath Sutendra; Linda Webster; Hunter C Champion; Brian Chiu; Alois Haromy; Evangelos D Michelakis
Endothelin axis is upregulated in human and rat right ventricular hypertrophy.

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All Publications

2013: Hunter C Champion
When to initiate intravenous therapy and/or refer.
The American journal of cardiology 2013;111(8 Suppl):21C-4C.
2013: M Patricia George; Mark T Gladwin; Siobhan Guyach; Christopher Janssen; Heather M Kling; Alison Morris; Jessica Murphy; Alexandra Brower; Jonathan P Carney; Hunter C Champion; Marc Simon; Rebecca Tarantelli; Karen A Norris
Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension.
American journal of respiratory cell and molecular biology 2013;48(3):374-81.
2013: Jayan Nagendran; Ian Paterson; Ivan M Rebeyka; David B Ross; Gopinath Sutendra; Linda Webster; Hunter C Champion; Brian Chiu; Alois Haromy; Evangelos D Michelakis
Endothelin axis is upregulated in human and rat right ventricular hypertrophy.
Circulation research 2013;112(2):347-54.
2012: Kapil Parakh; Stuart D Russell; Kranthi K Sitammagari; Ilan S Wittstein; Lili A Barouch; Kenneth L Baughman; Hunter C Champion; Bettina Heidecker; Daniel P Judge; Edward K Kasper; Michelle M Kittleson; Joshua M Hare
The variable natural history of idiopathic dilated cardiomyopathy.
The Israel Medical Association journal : IMAJ 2012;14(11):666-71.
2012: Robert Segal; Jochen Steppan; Dan E Berkowitz; Arthur L Burnett; Hunter C Champion; Johanna L Hannan; Jae Hyung Kim; Omer Kutlu; Xiaopu Liu; Trinity J Bivalacqua
Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.
Journal of andrology 2012;33(6):1169-75.
2012: Daniela Valdez-Jasso; Marc A Simon; Hunter C Champion; Michael S Sacks
A murine experimental model for the mechanical behaviour of viable right-ventricular myocardium.
The Journal of physiology 2012;590(Pt 18):4571-84.
2012: Anna R Hemnes; Karen B Maynard; Hunter C Champion; Linda Gleaves; Niki Penner; James West; John H Newman
Testosterone negatively regulates right ventricular load stress responses in mice.
Pulmonary circulation 2012;2(3):352-8.
2012: J Agustin Cruz; Archana Gangopadhyay; Andres I Rodriguez; Sruti Shiva; Yinna Wang; Nabil S Zeineh; Eileen M Bauer; Hunter C Champion; Philip M Bauer
Chronic hypoxia induces right heart failure in caveolin-1-/- mice.
American journal of physiology. Heart and circulatory physiology 2012;302(12):H2518-27.
2012: M Patricia George; Mark T Gladwin; Hunter C Champion; Karen A Norris; Alison Morris
Injection drug use as a "second hit" in the pathogenesis of HIV-associated pulmonary hypertension.
American journal of respiratory and critical care medicine 2012;185(11):1144-6.
2012: Nicholas K H Khoo; Ronald P Mason; Claudette M St Croix; Simon C Watkins; Nadiezhda Cantu-Medellin; Hunter C Champion; Jason E Devlin; Alexander M Fleming; Bruce Freeman; Eric E Kelley
Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study.
Free radical biology & medicine 2012;52(11-12):2312-9.
2012: G Frazziano; Hunter C Champion; Patrick J Pagano
NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone.
American journal of physiology. Heart and circulatory physiology 2012;302(11):H2166-77.
2012: Ferhaan Ahmad; Hunter C Champion; Naftali Kaminski
Toward systems biology of pulmonary hypertension.
Circulation 2012;125(12):1477-9.
2012: Alison Morris; Karen A Norris; Vikas Singh; Chad Steele; Yingze Zhang; Michelle Busch; Hunter C Champion; M Patricia George; Matthew R Gingo; Mark T Gladwin; Maria Hillenbrand; Cathy Kessinger; Lorrie Lucht; Deborah McMahon; Frank C Sciurba
Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era.
AIDS (London, England) 2012;26(6):731-40.
2012: Philip M Bauer; Maria J Calzada; Hunter C Champion; Monica Feijoo-Cuaresma; Joseph M Pilewski; Natasha M Rogers; Mingyi Yao; Brian Zuckerbraun; Eileen M Bauer; Jeff S Isenberg
Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.
Cardiovascular research 2012;93(4):682-93.
2012: R Saggar; Hunter C Champion; G D Lewis; R Naeije; D M Systrom; R Saggar
Pulmonary vascular responses to exercise: a haemodynamic observation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2012;39(2):231-4.
2012: Daniel J Kass; Katrina Loh; Mark Markowski; Revathi Rajkumar; Eileen Rattigan; Anjali Saqi; Asaf Savir; Liyang Yu; Ferhaan Ahmad; Rehan Kahloon; Hunter C Champion
Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats.
PloS one 2012;7(4):e35388.
2011: Ari L Zaiman; Hunter C Champion; rachel damico; Hazim El-Haddad; D Clark Files; Marc K Halushka; Paul M Hassoun; Laura Johnston; Priya Kesari; Richard N Kitsis; Shehzin Mozammel; Allen C Myers; Chang-Fu Peng; Larissa A Shimoda; Mara Swaim; Alan Thoms-Chesley; Michael T Crow
A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension.
Circulation 2011;124(23):2533-42.
2011: Milena A Gebska; Blake K Stevenson; Anna R Hemnes; Trinity J Bivalacqua; Azeb Haile; Geoffrey G Hesketh; Christopher I Murray; Ari L Zaiman; Marc K Halushka; Nispa Krongkaew; Travis D Strong; CA Cooke; Hazim El-Haddad; Rubin M Tuder; Dan E Berkowitz; Hunter C Champion
Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.
Cardiovascular research 2011;90(2):353-63.
2011: M Patricia George; Hunter C Champion; Joseph M Pilewski
Lung transplantation for pulmonary hypertension.
Pulmonary circulation 2011;1(2):182-91.
2011: Bettina Heidecker; Michelle M Kittleson; Edward K Kasper; Ilan S Wittstein; Hunter C Champion; Stuart D Russell; Ralph Hruban; E Rene Rodriguez; Kenneth L Baughman; Joshua M Hare
Transcriptomic biomarkers for the accurate diagnosis of myocarditis.
Circulation 2011;123(11):1174-84.
2011: Biljana Musicki; Hunter C Champion; Lewis Hsu; Trinity J Bivalacqua; Arthur L Burnett
Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis.
The journal of sexual medicine 2011;8(2):419-26.
2011: M Patricia George; Alexandra Brower; Heather Kling; Tim Shipley; Jan Kristoff; Todd A Reinhart; Michael Murphey-Corb; Mark T Gladwin; Hunter C Champion; Alison Morris; Karen A Norris
Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques.
AIDS research and human retroviruses 2011;27(2):103-11.
2011: V D Steen; Hunter C Champion
Is exercise-induced pulmonary hypertension ready for prime time in systemic sclerosis?
International journal of clinical practice. Supplement 2011;(169):1-3.
2010: Christian Gratzke; Travis D Strong; Milena A Gebska; Hunter C Champion; Christian G Stief; Arthur L Burnett; Trinity J Bivalacqua
Activated RhoA/Rho kinase impairs erectile function after cavernous nerve injury in rats.
The Journal of urology 2010;184(5):2197-204.
2010: Thomas J LaRocca; Martina Schwarzkopf; Perry Altman; Shihong Zhang; Achla Gupta; Ivone Gomes; Zikiar Alvin; Hunter C Champion; Georges Haddad; Roger J Hajjar; Lakshmi A Devi; Alison D Schecter; Sima T Tarzami
β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4.
Journal of cardiovascular pharmacology 2010;56(5):548-59.
2010: Christopher J Gregg; Jochen Steppan; Daniel R Gonzalez; Hunter C Champion; Alexander C Phan; Daniel Nyhan; Artin A Shoukas; Joshua M Hare; Lili A Barouch; Dan E Berkowitz
β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.
Anesthesia and analgesia 2010;111(4):870-7.
2010: Brian B Graham; Margaret M Mentink-Kane; Hazim El-Haddad; Shawn Purnell; Li Zhang; Ari L Zaiman; Elizabeth F Redente; David W H Riches; Paul M Hassoun; Angela Bandeira; Hunter C Champion; Ghazwan Butrous; Thomas A Wynn; Rubin M Tuder
Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
The American journal of pathology 2010;177(3):1549-61.
2010: Anthony R White; Sungwoo Ryoo; Lukasz Bugaj; David O Attarzadeh; Srikanth Thiyagarajan; Kexun Chen; Sarah Attwater; Bryce Abbot; Dechun Li; Hunter C Champion; Artin A Shoukas; Daniel Nyhan; Joshua M Hare; Dan E Berkowitz; Eric C Tuday
Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway.
European journal of applied physiology 2010;110(2):395-404.
2010: Trinity J Bivalacqua; Ashley E Ross; Travis D Strong; Milena A Gebska; Biljana Musicki; Hunter C Champion; Arthur L Burnett
Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice.
Urology 2010;76(2):510.e7-12.
2010: Arantza Campo; Stephen C Mathai; Jérôme Le Pavec; Ari L Zaiman; Laura K Hummers; Danielle Boyce; Traci Housten; Hunter C Champion; Noah Lechtzin; Fredrick M Wigley; Reda E Girgis; Paul M Hassoun
Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2010;182(2):252-60.
2010: Clarke G Tankersley; Roger D Peng; Djahida Bedga; Kathleen L Gabrielson; Hunter C Champion
Variation in echocardiographic and cardiac hemodynamic effects of PM and ozone inhalation exposure in strains related to Nppa and Npr1 gene knock-out mice.
Inhalation toxicology 2010;22(8):695-707.
2010: Thomas A White; Tyra A Witt; Shuchong Pan; Cheryl S Mueske; Laurel S Kleppe; Eric W Holroyd; Hunter C Champion; Robert D Simari
Tissue factor pathway inhibitor overexpression inhibits hypoxia-induced pulmonary hypertension.
American journal of respiratory cell and molecular biology 2010;43(1):35-45.
2010: Bettina Heidecker; guillaume lamirault; Edward K Kasper; Ilan S Wittstein; Hunter C Champion; Elayne Breton; Stuart D Russell; Jennifer Hall; Michelle M Kittleson; Kenneth L Baughman; Joshua M Hare
The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences.
European heart journal 2010;31(10):1188-96.
2010: Weiwen Deng; Trinity J Bivalacqua; Hunter C Champion; Wayne J G Hellstrom; Subramanyam N Murthy; Philip J Kadowitz
Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the lung for pulmonary hypertension.
Methods in molecular biology (Clifton, N.J.) 2010;610():309-21.
2010: Weiwen Deng; Trinity J Bivalacqua; Hunter C Champion; Wayne J G Hellstrom; Subramanyam N Murthy; Philip J Kadowitz
Superoxide dismutase - a target for gene therapeutic approach to reduce oxidative stress in erectile dysfunction.
Methods in molecular biology (Clifton, N.J.) 2010;610():213-27.
2010: Stephen C Mathai; M Bueso; Laura K Hummers; D Boyce; Noah Lechtzin; J Le Pavec; Arantza Campo; Hunter C Champion; T Housten; Paul R Forfia; Ari L Zaiman; Fredrick M Wigley; Reda E Girgis; Paul M Hassoun
Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(1):95-104.
2009: An L Moens; Jordan S Leyton-Mange; Xiaolin Niu; Ronghua Yang; Oscar Horacio Cingolani; Elisabeth K Arkenbout; Hunter C Champion; Djahida Bedja; Kathleen L Gabrielson; Juan Chen; Yong Xia; Ashley B Hale; Keith M Channon; Marc K Halushka; NORMAN BARKER; Floris L Wuyts; Pawel M Kaminski; Michael S Wolin; David A Kass; Lili A Barouch
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.
Journal of molecular and cellular cardiology 2009;47(5):576-85.
2009: Daniel Angelini; QINGNING SU; Kazuyo Yamaji-Kegan; Chunling Fan; Xingwu Teng; Paul M Hassoun; Stephen C Yang; Hunter C Champion; Rubin M Tuder; Roger Johns
Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
American journal of respiratory cell and molecular biology 2009;41(5):553-61.
2009: Jae Hyung Kim; Lukasz J Bugaj; Young Jun Oh; Trinity J Bivalacqua; Sungwoo Ryoo; Kevin G Soucy; Lakshmi Santhanam; Alanah Webb; Andre Camara; Gautam Sikka; Daniel Nyhan; Artin A Shoukas; Monica Ilies; David W Christianson; Hunter C Champion; Dan E Berkowitz
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;107(4):1249-57.
2009: Hunter C Champion; Evangelos D Michelakis; Paul M Hassoun
Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications.
Circulation 2009;120(11):992-1007.
2009: Anna R Hemnes; P R Forfia; Hunter C Champion
Assessment of pulmonary vasculature and right heart by invasive haemodynamics and echocardiography.
International journal of clinical practice. Supplement 2009;(162):4-19.
2009: Trinity J Bivalacqua; Biljana Musicki; Lewis Hsu; Mark T Gladwin; Arthur L Burnett; Hunter C Champion
Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism.
The journal of sexual medicine 2009;6(9):2494-504.
2009: Michelle M Kittleson; Diane V Skojec; Ilan S Wittstein; Hunter C Champion; Daniel P Judge; Lili A Barouch; Marc K Halushka; Joshua M Hare; Edward K Kasper; Stuart D Russell
The change in B-type natriuretic peptide levels over time predicts significant rejection in cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2009;28(7):704-9.
2009: Biljana Musicki; Ashley E Ross; Hunter C Champion; Arthur L Burnett; Trinity J Bivalacqua
Posttranslational modification of constitutive nitric oxide synthase in the penis.
Journal of andrology 2009;30(4):352-62.
2009: David B Badesch; Hunter C Champion; Miguel Angel Gomez Sanchez; Marius M Hoeper; James E Loyd; Alessandra Manes; Michael McGoon; Robert Naeije; Horst Olschewski; Ronald J Oudiz; Adam Torbicki
Diagnosis and assessment of pulmonary arterial hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S55-66.
2009: Hossein A Ghofrani; Robyn J Barst; Raymond L Benza; Hunter C Champion; Karen A Fagan; Friedrich Grimminger; Marc Humbert; Gérald Simonneau; Duncan J Stewart; Carlo Ventura; Lewis J Rubin
Future perspectives for the treatment of pulmonary arterial hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S108-17.
2009: Caitlin S Thompson-Torgerson; Hunter C Champion; Lakshmi Santhanam; Z Leah Harris; Artin A Shoukas
Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function.
American journal of physiology. Heart and circulatory physiology 2009;296(6):H1926-32.
2009: Eric S Weiss; Hunter C Champion; Jason A Williams; WM BAUMGARTNER; Ashish S Shah
Long-acting oral phosphodiesterase inhibition preconditions against reperfusion injury in an experimental lung transplantation model.
The Journal of thoracic and cardiovascular surgery 2009;137(5):1249-57.
2009: Jacob Abraham; James OTIS Mudd; Navin K Kapur; Navin Kapur; Kelly Klein; Hunter C Champion; Ilan S Wittstein
Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists.
Journal of the American College of Cardiology 2009;53(15):1320-5.
2009: Micah R Fisher; Paul R Forfia; Elzbieta Chamera; Traci Housten-Harris; Hunter C Champion; Reda E Girgis; Mary C Corretti; Paul M Hassoun
Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension.
American journal of respiratory and critical care medicine 2009;179(7):615-21.
2009: Daniel Angelini; QINGNING SU; Kazuyo Yamaji-Kegan; Chunling Fan; John T Skinner; Hunter C Champion; Michael T Crow; Roger Johns
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2009;296(4):L582-93.
2009: Stephen C Mathai; Laura K Hummers; Hunter C Champion; Fredrick M Wigley; Ari L Zaiman; Paul M Hassoun; Reda E Girgis
Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease.
Arthritis and rheumatism 2009;60(2):569-77.
2009: Trinity J Bivalacqua; Thomas E Sussan; Melina A Gebska; Travis D Strong; Dan E Berkowitz; Shyam Biswal; Arthur L Burnett; Hunter C Champion
Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.
The Journal of urology 2009;181(2):899-906.
2009: Thomas E Sussan; Tirumalai Rangasamy; David J Blake; Deepti Malhotra; Hazim El-Haddad; Djahida Bedja; Melinda S Yates; Ponvijay Kombairaju; Masayuki Yamamoto; Karen T Liby; Michael B. Sporn; Kathleen L Gabrielson; Hunter C Champion; Rubin M Tuder; Thomas W Kensler; Shyam Biswal
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):250-5.
2008: Manling Zhang; Norimichi Koitabashi; Takahiro Nagayama; Ryan Rambaran; Ning Feng; Eiki Takimoto; Trisha Koenke; Brian O'Rourke; Hunter C Champion; Michael T Crow; David A Kass
Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes.
Cellular signalling 2008;20(12):2231-6.
2008: Ryan J Tedford; Anna R Hemnes; Stuart D Russell; Ilan S Wittstein; Mobusher Mahmud; Ari L Zaiman; Stephen C Mathai; David R Thiemann; Paul M Hassoun; Reda E Girgis; Jonathan B Orens; Ashish S Shah; David D Yuh; John V Conte; Hunter C Champion
PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support.
Circulation. Heart failure 2008;1(4):213-9.
2008: Trinity J Bivalacqua; THOMAS GUZZO; Edward M Schaeffer; Milena A Gebska; Hunter C Champion; Arthur L Burnett; Mark L Gonzalgo
Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo.
Urology 2008;72(5):1169-73.
2008: Bettina Heidecker; Edward K Kasper; Ilan S Wittstein; Hunter C Champion; Elayne Breton; Stuart D Russell; Michelle M Kittleson; Kenneth L Baughman; Joshua M Hare
Transcriptomic biomarkers for individual risk assessment in new-onset heart failure.
Circulation 2008;118(3):238-46.
2008: Anna R Hemnes; Hunter C Champion
Right heart function and haemodynamics in pulmonary hypertension.
International journal of clinical practice. Supplement 2008;(160):11-9.
2008: Clarke G Tankersley; Hunter C Champion; Eiki Takimoto; Kathleen L Gabrielson; Djahida Bedja; Vikas Misra; Hazim El-Haddad; Richard Rabold; Wayne Mitzner
Exposure to inhaled particulate matter impairs cardiac function in senescent mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(1):R252-63.
2008: Paul R Forfia; Stephen C Mathai; Micah R Fisher; Traci Housten-Harris; Anna R Hemnes; Hunter C Champion; Reda E Girgis; Paul M Hassoun
Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2008;177(12):1364-9.
2008: An L Moens; Eiki Takimoto; Carlo G Tocchetti; Khalid Chakir; Djahida Bedja; Gianfranco Cormaci; Elizabeth A Ketner; Maulik Majmudar; Kathleen L Gabrielson; Marc K Halushka; James B Mitchell; Shyam Biswal; Keith M Channon; Michael S Wolin; Nicholas J Alp; Nazareno Paolocci; Hunter C Champion; David A Kass
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.
Circulation 2008;117(20):2626-36.
2008: An L Moens; Christiaan Vrints; Marc J Claeys; Jean-Pierre Timmermans; Hunter C Champion; David A Kass
Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease.
American journal of physiology. Heart and circulatory physiology 2008;294(5):H1971-7.
2008: T D Strong; Milena A Gebska; Hunter C Champion; Arthur L Burnett; Trinity J Bivalacqua
Stem and endothelial progenitor cells in erection biology.
International journal of impotence research 2008;20(3):243-54.
2008: Sungwoo Ryoo; Gaurav Gupta; Alexandre Benjo; Hyun Kyo Lim; Andre Camara; Gautam Sikka; Hyun Kyo Lim; Jayson Sohi; Lakshmi Santhanam; Kevin G Soucy; Eric Tuday; Ezra Baraban; Monica Ilies; Gary Gerstenblith; Daniel Nyhan; Artin A Shoukas; David W Christianson; Nicholas J Alp; Hunter C Champion; David L Huso; Dan E Berkowitz
Endothelial arginase II: a novel target for the treatment of atherosclerosis.
Circulation research 2008;102(8):923-32.
2008: Ari L Zaiman; Megan Podowski; Satya Medicherla; Kimberley Gordy; Fang Xu; Lijie Zhen; Larissa A Shimoda; Enid R Neptune; Linda Higgins; Alison Murphy; Sarvajit Chakravarty; Protter Andrew; Pravin B Sehgal; Hunter C Champion; Rubin M Tuder
Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.
American journal of respiratory and critical care medicine 2008;177(8):896-905.
2008: An L Moens; Hunter C Champion; Marc J Claeys; Barbara Tavazzi; Pawel M Kaminski; Michael S Wolin; Dirk J Borgonjon; Luc Van Nassauw; Azeb Haile; Menekhem M Zviman; Djahida Bedja; Floris L Wuyts; Rebecca S Elsaesser; Paul Cos; Kathleen L Gabrielson; Giuseppe Lazzarino; Nazareno Paolocci; Jean-Pierre Timmermans; Christiaan Vrints; David A Kass
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury.
Circulation 2008;117(14):1810-9.
2008: Dmitry N Grigoryev; Stephen C Mathai; Micah R Fisher; Reda E Girgis; Ari L Zaiman; Traci Housten-Harris; Chris Cheadle; Li Gao; Laura K Hummers; Hunter C Champion; Joe G. N. Garcia; Fredrick M Wigley; Rubin M Tuder; Kathleen C Barnes; Paul M Hassoun
Identification of candidate genes in scleroderma-related pulmonary arterial hypertension.
Translational research : the journal of laboratory and clinical medicine 2008;151(4):197-207.
2008: Hunter C Champion
The heart in scleroderma.
Rheumatic diseases clinics of North America 2008;34(1):181-90; viii.
2008: Travis D Strong; Milena A Gebska; Arthur L Burnett; Hunter C Champion; Trinity J Bivalacqua
Endothelium-specific gene and stem cell-based therapy for erectile dysfunction.
Asian journal of andrology 2008;10(1):14-22.
2008: Anna R Hemnes; Ari L Zaiman; Hunter C Champion
PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation.
American journal of physiology. Lung cellular and molecular physiology 2008;294(1):L24-33.
2007: T Rinda Soong; Lili A Barouch; Hunter C Champion; Fredrick M Wigley; Marc K Halushka
New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy--a report of 2 cases.
Human pathology 2007;38(12):1858-63.
2007: David A Kass; Hunter C Champion; Joseph A Beavo
Phosphodiesterase type 5: expanding roles in cardiovascular regulation.
Circulation research 2007;101(11):1084-95.
2007: Bobby D Nossaman; Trinity J Bivalacqua; Hunter C Champion; Syed R Baber; Philip J Kadowitz
Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat.
Journal of cardiovascular pharmacology 2007;50(4):358-66.
2007: T D Strong; Hunter C Champion; P J Kadowitz; Trinity J Bivalacqua
Reply: potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells.
International journal of impotence research 2007;19(5):530.
2007: David A Kass; Eiki Takimoto; Takahiro Nagayama; Hunter C Champion
Phosphodiesterase regulation of nitric oxide signaling.
Cardiovascular research 2007;75(2):303-14.
2007: Trinity J Bivalacqua; Muammer Kendirci; Hunter C Champion; Wayne J G Hellstrom; Karl-Erik Andersson; Petter Hedlund
Dysregulation of cGMP-dependent protein kinase 1 (PKG-1) impairs erectile function in diabetic rats: influence of in vivo gene therapy of PKG1alpha.
BJU international 2007;99(6):1488-94.
2007: Trinity J Bivalacqua; Tongyun Liu; Biljana Musicki; Hunter C Champion; Arthur L Burnett
Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis.
European urology 2007;51(6):1732-40.
2007: Mobusher Mahmud; Hunter C Champion
Right ventricular failure complicating heart failure: pathophysiology, significance, and management strategies.
Current cardiology reports 2007;9(3):200-8.
2007: Michelle M Kittleson; Valeriani Bead; Michael Fradley; Marcus E St John; Hunter C Champion; Edward K Kasper; Stuart D Russell; Ilan S Wittstein; Joshua M Hare
Elevated uric acid levels predict allograft vasculopathy in cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2007;26(5):498-503.
2007: Reda E Girgis; Shehzin Mozammel; Hunter C Champion; Dechun Li; Xinqi Peng; Larissa A Shimoda; Rubin M Tuder; Roger Johns; Paul M Hassoun
Regression of chronic hypoxic pulmonary hypertension by simvastatin.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1105-10.
2007: Eiki Takimoto; Diego F Belardi; Carlo G Tocchetti; Susan Vahebi; Gianfrancesco Cormaci; Elizabeth A Ketner; An L Moens; Hunter C Champion; David A Kass
Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
Circulation 2007;115(16):2159-67.
2007: Lewis Hsu; Hunter C Champion; Sally A Campbell-Lee; Trinity J Bivalacqua; Elizabeth A Manci; Bhalchandra A Diwan; Daniel M Schimel; Audrey E Cochard; Xunde Wang; Alan N Schechter; Constance T Noguchi; Mark T Gladwin
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Blood 2007;109(7):3088-98.
2007: Paul R Forfia; Myung Lee; Richard S Tunin; Mobusher Mahmud; Hunter C Champion; David A Kass
Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart.
Journal of the American College of Cardiology 2007;49(10):1079-88.
2007: Michelle M Kittleson; Marcus E St John; Valeriani Bead; Hunter C Champion; Edward K Kasper; Stuart D Russell; Ilan S Wittstein; Joshua M Hare
Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels.
Heart (British Cardiac Society) 2007;93(3):365-7.
2007: Stephen C Mathai; Reda E Girgis; Micah R Fisher; Hunter C Champion; Traci Housten-Harris; Ari L Zaiman; Paul M Hassoun
Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(3):469-75.
2007: Trinity J Bivalacqua; Arthur L Burnett; Wayne J G Hellstrom; Hunter C Champion
Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase.
American journal of physiology. Heart and circulatory physiology 2007;292(3):H1340-51.
2007: Trinity J Bivalacqua; Weiwen Deng; Muammer Kendirci; Mustafa F Usta; Christine Robinson; Bradley K Taylor; Subramanyam N Murthy; Hunter C Champion; Wayne J G Hellstrom; Philip J Kadowitz
Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction.
American journal of physiology. Heart and circulatory physiology 2007;292(3):H1278-90.
2007: Navin K Kapur; Clayton B Deming; Sunil Kapur; Ce Bian; Hunter C Champion; J Kevin Donahue; David A Kass; Jeffrey J Rade
Hemodynamic modulation of endocardial thromboresistance.
Circulation 2007;115(1):67-75.
2007: M Y Maslov; Vadappuram P Chacko; Matthias Stuber; An L Moens; David A Kass; Hunter C Champion; Robert G Weiss
Altered high-energy phosphate metabolism predicts contractile dysfunction and subsequent ventricular remodeling in pressure-overload hypertrophy mice.
American journal of physiology. Heart and circulatory physiology 2007;292(1):H387-91.
2007: Kenneth C Bilchick; Jennifer G Duncan; Rajashree Ravi; Eiki Takimoto; Hunter C Champion; Wei Dong Gao; Linda B Stull; David A Kass; Anne M Murphy
Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
American journal of physiology. Heart and circulatory physiology 2007;292(1):H318-25.
2006: Muammer Kendirci; Patrick E Teloken; Hunter C Champion; Wayne J G Hellstrom; Trinity J Bivalacqua
Gene therapy for erectile dysfunction: fact or fiction?
European urology 2006;50(6):1208-22.
2006: Kazuyo Yamaji-Kegan; QINGNING SU; Daniel Angelini; Hunter C Champion; Roger Johns
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
American journal of physiology. Lung cellular and molecular physiology 2006;291(6):L1159-68.
2006: Arthur L Burnett; Trinity J Bivalacqua; Hunter C Champion; Biljana Musicki
Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism.
The journal of sexual medicine 2006;3(6):1077-84.
2006: Paul R Forfia; Micah R Fisher; Stephen C Mathai; Traci Housten-Harris; Anna R Hemnes; Barry A Borlaug; Elzbieta Chamera; Mary C Corretti; Hunter C Champion; Theodore P Abraham; Reda E Girgis; Paul M Hassoun
Tricuspid annular displacement predicts survival in pulmonary hypertension.
American journal of respiratory and critical care medicine 2006;174(9):1034-41.
2006: Micah R Fisher; Stephen C Mathai; Hunter C Champion; Reda E Girgis; Traci Housten-Harris; Laura K Hummers; Jerry Krishnan; Fredrick M Wigley; Paul M Hassoun
Clinical differences between idiopathic and scleroderma-related pulmonary hypertension.
Arthritis and rheumatism 2006;54(9):3043-50.
2006: John Elrod; Mark R Duranski; Will Langston; James J M Greer; Ling Tao; Tammy R Dugas; Christopher Kevil; Hunter C Champion; David J Lefer
eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling.
Circulation research 2006;99(1):78-85.
2006: Anna R Hemnes; Hunter C Champion
Sildenafil, a PDE5 inhibitor, in the treatment of pulmonary hypertension.
Expert review of cardiovascular therapy 2006;4(3):293-300.
2006: Arthur L Burnett; Trinity J Bivalacqua; Hunter C Champion; Biljana Musicki
Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism.
Urology 2006;67(5):1043-8.
2006: Liming Jin; Tongyun Liu; Gwen A Lagoda; Hunter C Champion; Trinity J Bivalacqua; Arthur L Burnett
Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):536-8.
2006: K Joseph Hurt; Sena F Sezen; Hunter C Champion; Julie K Crone; Michael A Palese; Paul L Huang; Akira Sawa; Xiaojiang Luo; Biljana Musicki; Solomon H Snyder; Arthur L Burnett
Alternatively spliced neuronal nitric oxide synthase mediates penile erection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3440-3.
2006: Anthony R White; Sungwoo Ryoo; Dechun Li; Hunter C Champion; Jochen Steppan; Danming Wang; Daniel Nyhan; Artin A Shoukas; Joshua M Hare; Dan E Berkowitz
Knockdown of arginase I restores NO signaling in the vasculature of old rats.
Hypertension 2006;47(2):245-51.
2006: Steven P Schulman; Lewis C Becker; David A Kass; Hunter C Champion; Michael L Terrin; Sandra Forman; Kavita V Ernst; Mark D Kelemen; Susan N Townsend; Anne Capriotti; Joshua M Hare; Gary Gerstenblith
L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.
JAMA : the journal of the American Medical Association 2006;295(1):58-64.
2005: Katrina M Miranda; Tatsuo Katori; Claudia L Torres de Holding; Lynta Thomas; Lisa A Ridnour; William J McLendon; Stephanie M Cologna; Andrew S Dutton; Hunter C Champion; Daniele Mancardi; Carlo G Tocchetti; Joseph E Saavedra; Larry K Keefer; Kendall N Houk; Jon M Fukuto; David A Kass; Nazareno Paolocci; David A Wink
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
Journal of medicinal chemistry 2005;48(26):8220-8.
2005: Biljana Musicki; Hunter C Champion; Robyn E Becker; Melissa F Kramer; Tongyun Liu; Sena F Sezen; Arthur L Burnett
In vivo analysis of chronic phosphodiesterase-5 inhibition with sildenafil in penile erectile tissues: no tachyphylaxis effect.
The Journal of urology 2005;174(4 Pt 1):1493-6.
2005: Annette Wilson; Wen Zhou; Hunter C Champion; Sean Alber; Zi-Lue Tang; Steven Kennel; simon simon watkins; Leaf Huang; Bruce R Pitt; Song Li
Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):510-8.
2005: Tomohisa Nagoshi; Takashi Matsui; Takuma Aoyama; Annarosa Leri; Piero Anversa; Ling Li; Wataru Ogawa; Federica del Monte; Judith K Gwathmey; luanda grazette; Brian Hemmings; Brian Hemmings; David A Kass; Hunter C Champion; Anthony Rosenzweig
PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury.
The Journal of clinical investigation 2005;115(8):2128-38.
2005: Reda E Girgis; Hunter C Champion; Gregory B Diette; Roger Johns; Solbert Permutt; JIM SYLVESTER
Decreased exhaled nitric oxide in pulmonary arterial hypertension: response to bosentan therapy.
American journal of respiratory and critical care medicine 2005;172(3):352-7.
2005: Biljana Musicki; Hunter C Champion; Robyn E Becker; Tongyun Liu; Melissa F Kramer; Arthur L Burnett
Erection capability is potentiated by long-term sildenafil treatment: role of blood flow-induced endothelial nitric-oxide synthase phosphorylation.
Molecular pharmacology 2005;68(1):226-32.
2005: Richard H Sohn; Clayton B Deming; David C Johns; Hunter C Champion; Ce Bian; Kevin Gardner; Jeffrey J Rade
Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B.
Blood 2005;105(10):3910-7.
2005: Eiki Takimoto; Hunter C Champion; Manxiang Li; Shuxun Ren; E Rene Rodriguez; Barbara Tavazzi; Giuseppe Lazzarino; Nazareno Paolocci; Kathleen L Gabrielson; Yibin Wang; David A Kass
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.
The Journal of clinical investigation 2005;115(5):1221-31.
2005: Hunter C Champion
Targeting protein phosphatase 1 in heart failure.
Circulation research 2005;96(7):708-10.
2005: Trinity J Bivalacqua; Mustafa F Usta; Muammer Kendirci; Leena Pradhan; Xavier Alvarez; Hunter C Champion; Philip J Kadowitz; Wayne J G Hellstrom
Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy.
The journal of sexual medicine 2005;2(2):187-97; discussion 197-8.
2005: Patrick Segers; Dimitrios Georgakopoulos; Marina Afanasyeva; Hunter C Champion; Daniel P Judge; Huntly Millar; Pascal Verdonck; David A Kass; Nikos Stergiopulos; Nico Westerhof
Conductance catheter-based assessment of arterial input impedance, arterial function, and ventricular-vascular interaction in mice.
American journal of physiology. Heart and circulatory physiology 2005;288(3):H1157-64.
2005: Ilan S Wittstein; David R Thiemann; João A C Lima; Kenneth L Baughman; Steven P Schulman; Gary Gerstenblith; Katherine C Wu; Jeffrey J Rade; Trinity J Bivalacqua; Hunter C Champion
Neurohumoral features of myocardial stunning due to sudden emotional stress.
The New England journal of medicine 2005;352(6):539-48.
2005: Hunter C Champion; Trinity J Bivalacqua; Eiki Takimoto; David A Kass; Arthur L Burnett
Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1661-6.
2005: Eiki Takimoto; Hunter C Champion; Manxiang Li; Diego F Belardi; Shuxun Ren; E Rene Rodriguez; Djahida Bedja; Kathleen L Gabrielson; Yibin Wang; David A Kass
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
Nature medicine 2005;11(2):214-22.
2005: Eiki Takimoto; Hunter C Champion; Diego F Belardi; Javid Moslehi; Marco Mongillo; Evanthia Mergia; David C Montrose; Takayoshi Isoda; Kate Aufiero; Manuela Zaccolo; Wolfgang R Dostmann; Carolyn J Smith; David A Kass
cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
Circulation research 2005;96(1):100-9.
2005: Trinity J Bivalacqua; Biljana Musicki; Mustafa F Usta; Hunter C Champion; Philip J Kadowitz; Arthur L Burnett; Wayne J G Hellstrom
Endothelial nitric oxide synthase gene therapy for erectile dysfunction.
Current pharmaceutical design 2005;11(31):4059-67.
2004: Trinity J Bivalacqua; Hunter C Champion; Mustafa F Usta; Selim Cellek; Kanchan Chitaley; R Clinton Webb; Ronald W Lewis; Thomas M Mills; Wayne J G Hellstrom; Philip J Kadowitz
RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(24):9121-6.
2004: Hunter C Champion; Dimitrios Georgakopoulos; Eiki Takimoto; Takayoshi Isoda; Yibin Wang; David A Kass
Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3.
Circulation research 2004;94(5):657-63.
2004: Hunter C Champion; David A Kass
Calcium handler mishandles heart.
Nature medicine 2004;10(3):239-40.
2004: Trinity J Bivalacqua; Mustafa F Usta; Hunter C Champion; Somboon Leungwattanakij; Paul A Dabisch; Dennis B McNamara; Philip J Kadowitz; Wayne J G Hellstrom
Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats.
International journal of impotence research 2004;16(1):21-9.
2004: Bobby D Nossaman; Paul A Dabisch; John T Liles; Syed R Baber; Hunter C Champion; Alan D Kaye; CJ Feng; M Anwar; Trinity J Bivalacqua; JA Santiago; Bracken J De Witt; Philip J Kadowitz
Peroxynitrite does not impair pulmonary and systemic vascular responses.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(2):455-62.
2004: Trinity J Bivalacqua; Weiwen Deng; Hunter C Champion; Wayne J G Hellstrom; Philip J Kadowitz
Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction.
Methods in molecular biology (Clifton, N.J.) 2004;279():173-85.
2003: Hunter C Champion; Dimitrios Georgakopoulos; Saptarsi Haldar; Lili Wang; Yibin Wang; David A Kass
Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine heart: application to study of phospholamban physiology.
Circulation 2003;108(22):2790-7.
2003: Trinity J Bivalacqua; Mustafa F Usta; Hunter C Champion; Philip J Kadowitz; Wayne J G Hellstrom
Endothelial dysfunction in erectile dysfunction: role of the endothelium in erectile physiology and disease.
Journal of andrology 2003;24(6 Suppl):S17-37.
2003: Dan E Berkowitz; Ron White; Dechun Li; Khalid M Minhas; Amy Cernetich; Soonyul Kim; Sean Burke; Artin A Shoukas; Daniel Nyhan; Hunter C Champion; Joshua M Hare
Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
Circulation 2003;108(16):2000-6.
2003: Syed R Baber; Hunter C Champion; Trinity J Bivalacqua; Albert L Hyman; Philip J Kadowitz
Role of cyclooxygenase-2 in the generation of vasoactive prostanoids in the rat pulmonary and systemic vascular beds.
Circulation 2003;108(7):896-901.
2003: Xingwu Teng; Dechun Li; Hunter C Champion; Roger Johns
FIZZ1/RELMalpha, a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties.
Circulation research 2003;92(10):1065-7.
2003: Trinity J Bivalacqua; Mustafa F Usta; Hunter C Champion; Dave Adams; Dennis B Namara; Asim B Abdel-Mageed; Philip J Kadowitz; Wayne J G Hellstrom
Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.
The Journal of urology 2003;169(5):1911-7.
2003: Nazareno Paolocci; Tatsuo Katori; Hunter C Champion; Marcus E St John; Katrina M Miranda; Jon M Fukuto; David A Wink; David A Kass
Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5537-42.
2003: Trinity J Bivalacqua; Jeffrey S Armstrong; John Biggerstaff; Asim B Abdel-Mageed; Philip J Kadowitz; Wayne J G Hellstrom; Hunter C Champion
Gene transfer of extracellular SOD to the penis reduces O2-* and improves erectile function in aged rats.
American journal of physiology. Heart and circulatory physiology 2003;284(4):H1408-21.
2003: Somboon Leungwattanakij; Trinity J Bivalacqua; Mustafa F Usta; Dae-Yul Yang; Jae-Seog Hyun; Hunter C Champion; Asim B Abdel-Mageed; Wayne J G Hellstrom
Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum.
Journal of andrology 2003;24(2):239-45.
2003: Hunter C Champion; Trinity J Bivalacqua; Robert L Pierce; William A Murphy; David H Coy; Albert L Hyman; Philip J Kadowitz
Responses to human CGRP, ADM, and PAMP in human thymic arteries.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;284(2):R531-7.
2003: Hunter C Champion; Michel W Skaf; Joshua M Hare
Role of nitric oxide in the pathophysiology of heart failure.
Heart failure reviews 2003;8(1):35-46.
2002: Kanchan Chitaley; Trinity J Bivalacqua; Hunter C Champion; Mustafa F Usta; Wayne J G Hellstrom; Thomas M Mills; R Clinton Webb
Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats.
Biochemical and biophysical research communications 2002;298(3):427-32.
2002: Trinity J Bivalacqua; Albert L Hyman; Philip J Kadowitz; Nazareno Paolocci; David A Kass; Hunter C Champion
Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse. Influence of gene transfer in vivo.
Regulatory peptides 2002;108(2-3):129-33.
2002: Trinity J Bivalacqua; Hunter C Champion; Wayne J G Hellstrom
Implications of nitric oxide synthase isoforms in the pathophysiology of Peyronie's disease.
International journal of impotence research 2002;14(5):345-52.
2002: Hunter C Champion; Trinity J Bivalacqua; Stanley S Greenberg; Thomas D Giles; Albert L Hyman; Philip J Kadowitz
Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13248-53.
2002: Trinity J Bivalacqua; Hunter C Champion; Mrugeshkumar K Shah; Bracken J De Witt; Edward Inscho; Philip J Kadowitz
Comparative responses to alpha,beta-methylene-ATP in cat pulmonary, mesenteric, and hindquarter vascular beds.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(4):1287-95.
2002: Trinity J Bivalacqua; Hunter C Champion; David G Lambert; Philip J Kadowitz
Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(6):R1696-709.
2002: Luis A Ortiz; Hunter C Champion; Joseph A Lasky; Federica Gambelli; Evelyne Gozal; Gary Hoyle; Mary B Beasley; Albert L Hyman; Mitchell Friedman; Philip J Kadowitz
Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-kappaB and AP-1.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1209-21.
2002: Hunter C Champion; Trinity J Bivalacqua; James E Zadina; Abba J Kastin; Albert L Hyman; Philip J Kadowitz
Role of nitric oxide in mediating vasodilator responses to opioid peptides in the rat.
Clinical and experimental pharmacology & physiology 2002;29(3):229-32.
2001: Trinity J Bivalacqua; Hunter C Champion; Asim B Abdel-Mageed; Philip J Kadowitz; Wayne J G Hellstrom
Gene transfer of prepro-calcitonin gene-related peptide restores erectile function in the aged rat.
Biology of reproduction 2001;65(5):1371-7.
2001: Mrugeshkumar K Shah; Hunter C Champion; Trinity J Bivalacqua; Philip J Kadowitz
Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat.
Life sciences 2001;69(21):2561-71.
2001: Hunter C Champion; Robert L Pierce; Trinity J Bivalacqua; William A Murphy; David H Coy; Philip J Kadowitz
Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat.
Peptides 2001;22(9):1427-34.
2001: Mrugeshkumar K Shah; Trinity J Bivalacqua; Hunter C Champion; Philip J Kadowitz
Vasodilator responses to ATP and UTP are cAMP dependent in the mesenteric vascular bed of the cat.
Journal of cardiovascular pharmacology and therapeutics 2001;6(3):287-95.
2001: Trinity J Bivalacqua; Hunter C Champion; Bracken J De Witt; J E Saavedra; Joseph A Hrabie; Larry K Keefer; Philip J Kadowitz
Analysis of vasodilator responses to novel nitric oxide donors in the hindquarters vascular bed of the cat.
Journal of cardiovascular pharmacology 2001;38(1):120-9.
2001: Suresh C Sikka; Hunter C Champion; Trinity J Bivalacqua; LS Estrada; R Wang; M Rajasekaran; B B Aggarwal; Wayne J G Hellstrom
Role of genitourinary inflammation in infertility: synergistic effect of lipopolysaccharide and interferon-gamma on human spermatozoa.
International journal of andrology 2001;24(3):136-41.
2001: Trinity J Bivalacqua; Wayne J G Hellstrom; Philip J Kadowitz; Hunter C Champion
Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction.
Biochemical and biophysical research communications 2001;283(4):923-7.
2001: Trinity J Bivalacqua; Hunter C Champion; Somboon Leungwattanakij; Dae-Yul Yang; Jae-Seog Hyun; Asim B Abdel-Mageed; Suresh C Sikka; Philip J Kadowitz; Wayne J G Hellstrom
Evaluation of nitric oxide synthase and arginase in the induction of a Peyronie's-like condition in the rat.
Journal of andrology 2001;22(3):497-506.
2001: PC Doherty; Trinity J Bivalacqua; Hunter C Champion; Philip J Kadowitz; B Greenwood-Van Meerveld; I Berzetei-Gurske; Wayne J G Hellstrom
Direct effects of selective type 5 phosphodiesterase inhibitors alone or with other vasodilators on the erectile response in cats.
The Journal of urology 2001;165(3):1004-9.
2001: R Yoast; Michael A. Williams; SD Deitchman; Hunter C Champion
Report of the Council on Scientific Affairs: methadone maintenance and needle-exchange programs to reduce the medical and public health consequences of drug abuse.
Journal of addictive diseases 2001;20(2):15-40.
2000: Giuseppina Mazzocchi; Gian Paolo Rossi; Ludwik K Malendowicz; Hunter C Champion; Gastone G Nussdorfer
Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells.
FEBS letters 2000;487(2):194-8.
2000: Trinity J Bivalacqua; Hunter C Champion; Wayne J G Hellstrom; Philip J Kadowitz
Pharmacotherapy for erectile dysfunction.
Trends in pharmacological sciences 2000;21(12):484-9.
2000: Bracken J De Witt; E A Garrison; Hunter C Champion; Philip J Kadowitz
L-163,491 is a partial angiotensin AT(1) receptor agonist in the hindquarters vascular bed of the cat.
European journal of pharmacology 2000;404(1-2):213-9.
2000: Trinity J Bivalacqua; Hunter C Champion; Y S Mehta; Asim B Abdel-Mageed; Suresh C Sikka; Louis J Ignarro; Philip J Kadowitz; Wayne J G Hellstrom
Adenoviral gene transfer of endothelial nitric oxide synthase (eNOS) to the penis improves age-related erectile dysfunction in the rat.
International journal of impotence research 2000;12 Suppl 3():S8-17.
2000: Hunter C Champion; Philip J Kadowitz
Vasodilator responses to ATP and UTP are not dependent on nitric oxide release, K+(ATP) channel activation, or the release of vasodilator prostaglandins in the hindlimb vascular bed of the cat.
Canadian journal of physiology and pharmacology 2000;78(8):612-21.
2000: Barry D Dickinson; RD Altman; SD Deitchman; Hunter C Champion
Safety of over-the-counter inhalers for asthma: report of the council on scientific affairs.
Chest 2000;118(2):522-6.
2000: Mrugeshkumar K Shah; Stephanie Y Hugghins; Hunter C Champion; Trinity J Bivalacqua
New therapies for treating hypertension: what every physician should know.
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 2000;152(7):334-44.
2000: Stephanie Y Hugghins; Hunter C Champion; G Cheng; Philip J Kadowitz; James R Jeter
Vasorelaxant responses to endomorphins, nociceptin, albuterol, and adrenomedullin in isolated rat aorta.
Life sciences 2000;67(4):471-6.
2000: Paola G Andreis; Anna Markowska; Hunter C Champion; Giuseppina Mazzocchi; Ludwik K Malendowicz; Gastone G Nussdorfer
Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism.
Endocrinology 2000;141(6):2098-104.
2000: Trinity J Bivalacqua; E K Diner; T E Novak; Y Vohra; Suresh C Sikka; Hunter C Champion; Philip J Kadowitz; Wayne J G Hellstrom
A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression.
The Journal of urology 2000;163(6):1992-8.
2000: Trinity J Bivalacqua; Hunter C Champion; S K Purohit; William A Murphy; David H Coy; Philip J Kadowitz; Wayne J G Hellstrom
Nitric oxide-mediated erectile effects of galantide but not galanin in vivo.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2000;4(2):94-102.
2000: Hunter C Champion; Trinity J Bivalacqua; K Toyoda; D D Heistad; Albert L Hyman; Philip J Kadowitz
In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse.
Circulation 2000;101(8):923-30.
2000: Hunter C Champion; D J Villnave; A Tower; Philip J Kadowitz; Albert L Hyman
A novel right-heart catheterization technique for in vivo measurement of vascular responses in lungs of intact mice.
American journal of physiology. Heart and circulatory physiology 2000;278(1):H8-H15.
1999: Giuseppina Mazzocchi; Giovanna Albertin; Paola G Andreis; Giuliano Neri; Ludwik K Malendowicz; Hunter C Champion; Meltem Bahcelioglu; PJ Kadowitz; Gastone G Nussdorfer
Distribution, functional role, and signaling mechanism of adrenomedullin receptors in the rat adrenal gland.
Peptides 1999;20(12):1479-87.
1999: Trinity J Bivalacqua; Hunter C Champion; R Wang; Philip J Kadowitz; PC Doherty; Wayne J G Hellstrom
Feline penile erection induced by transurethral administration of sodium nitroprusside.
Urological research 1999;27(6):432-6.
1999: Hunter C Champion; G G Nussdorfer; Philip J Kadowitz
Structure-activity relationships of adrenomedullin in the circulation and adrenal gland.
Regulatory peptides 1999;85(1):1-8.
1999: Trinity J Bivalacqua; A Dalal; Hunter C Champion; Philip J Kadowitz
Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.
The American journal of physiology 1999;277(5 Pt 1):E838-47.
1999: Trinity J Bivalacqua; Hunter C Champion; M Rajasekaran; Suresh C Sikka; Philip J Kadowitz; PC Doherty; Wayne J G Hellstrom
Potentiation of erectile response and cAMP accumulation by combination of prostaglandin E1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE 4).
The Journal of urology 1999;162(5):1848-55.
1999: Hunter C Champion; Trinity J Bivalacqua; DG Lambert; Rasheed A Abassi; Philip J Kadowitz
Analysis of vasoconstrictor responses to histamine in the hindlimb vascular bed of the rabbit.
The American journal of physiology 1999;277(4 Pt 2):R1179-87.
1999: Hunter C Champion; Trinity J Bivalacqua; Albert L Hyman; Louis J Ignarro; Wayne J G Hellstrom; Philip J Kadowitz
Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11648-52.
1999: Hunter C Champion; Trinity J Bivalacqua; Fiona M D'Souza; Luis A Ortiz; James R Jeter; K Toyoda; D D Heistad; Albert L Hyman; Philip J Kadowitz
Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.
Circulation research 1999;84(12):1422-32.
1999: Hunter C Champion; Trinity J Bivalacqua; R Wang; Philip J Kadowitz; Larry K Keefer; J E Saavedra; Joseph A Hrabie; PC Doherty; Wayne J G Hellstrom
Induction of penile erection by intracavernosal and transurethral administration of novel nitric oxide donors in the cat.
The Journal of urology 1999;161(6):2013-9.
1999: Anna S Belloni; Gian Paolo Rossi; Paola G Andreis; Francesco Aragona; Hunter C Champion; PJ Kadowitz; WA Murphy; DH Coy; Gastone G Nussdorfer
Proadrenomedullin N-terminal 20 peptide (PAMP), acting through PAMP(12-20)-sensitive receptors, inhibits Ca2+-dependent, agonist-stimulated secretion of human adrenal glands.
Hypertension 1999;33(5):1185-9.
1999: Anna S Belloni; Paola G Andreis; V Meneghelli; Hunter C Champion; PJ Kadowitz; DH Coy; WA Murphy; Gastone G Nussdorfer
Adrenomedullin and calcitonin gene-related peptide (CGRP) interact with a common receptor of the CGRP1 subtype in the human adrenal zona glomerulosa.
Endocrine research 1999;25(1):29-34.
1999: Hunter C Champion; Philip J Kadowitz
Vasodepressor responses to [D-Ala2]-endomorphin 2 (TAPP) are mediated by an L-NAME-sensitive mechanism in the rat.
Journal of cardiovascular pharmacology 1999;33(2):280-4.
1999: Hunter C Champion; Trinity J Bivalacqua; James E Zadina; Abba J Kastin; Philip J Kadowitz
Vasodilator responses to the endomorphin peptides, but not nociceptin/OFQ, are mediated by nitric oxide release.
Annals of the New York Academy of Sciences 1999;897():165-72.
1999: Hunter C Champion; Trinity J Bivalacqua; DG Lambert; Dennis B McNamara; Philip J Kadowitz
Analysis of the effects of candesartan on responses to angiotensin II in the hindquarters vascular bed of the cat.
Journal of the American Society of Nephrology : JASN 1999;10 Suppl 11():S101-3.
1999: Trinity J Bivalacqua; A Dalal; DG Lambert; Hunter C Champion; Philip J Kadowitz
Effects of candesartan and PD123319 on responses to angiotensin II in the anesthetized mouse.
Journal of the American Society of Nephrology : JASN 1999;10 Suppl 11():S98-100.
1999: Hunter C Champion; Trinity J Bivalacqua; DG Lambert; Dennis B McNamara; Philip J Kadowitz
The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat.
Journal of the American Society of Nephrology : JASN 1999;10 Suppl 11():S95-7.
1998: Hunter C Champion; Robert L Pierce; Philip J Kadowitz
Nociceptin, a novel endogenous ligand for the ORL1 receptor, dilates isolated resistance arteries from the rat.
Regulatory peptides 1998;78(1-3):69-74.
1998: Hunter C Champion; Trinity J Bivalacqua; R Wang; Wayne J G Hellstrom; Philip J Kadowitz
[Tyr1]-nociceptin and nociceptin have similar naloxone-insensitive erectile activity in the cat.
Journal of andrology 1998;19(6):747-53.
1998: Trinity J Bivalacqua; M Rajasekaran; Hunter C Champion; R Wang; Suresh C Sikka; Philip J Kadowitz; Wayne J G Hellstrom
The influence of castration on pharmacologically induced penile erection in the cat.
Journal of andrology 1998;19(5):551-7.
1998: Anna S Belloni; Paola G Andreis; Gian Paolo Rossi; Hunter C Champion; PJ Kadowitz; WA Murphy; DH Coy; Gastone G Nussdorfer
Structure-activity relationships of adrenomedullin in the adrenal gland.
Endocrine research 1998;24(3-4):729-30.
1998: Hunter C Champion; Philip J Kadowitz
Influence of nimodipine on vasoconstrictor responses in the hindquarters vascular bed of the cat.
The Journal of pharmacy and pharmacology 1998;50(6):673-80.
1998: Dennis B McNamara; Hunter C Champion; Philip J Kadowitz
Pharmacologic management of peripheral vascular disease.
The Surgical clinics of North America 1998;78(3):447-64.
1998: Hunter C Champion; Philip J Kadowitz
D-[Ala2]endomorphin 2 and endomorphin 2 have nitric oxide-dependent vasodilator activity in rats.
The American journal of physiology 1998;274(5 Pt 2):H1690-7.
1998: Bulent Gumusel; Q Hao; Albert L Hyman; Philip J Kadowitz; Hunter C Champion; J K Chang; Jawahar Mehta; Howard Lippton
Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats.
The American journal of physiology 1998;274(4 Pt 2):H1255-63.
1998: Albert L Hyman; Q Hao; A Tower; Philip J Kadowitz; Hunter C Champion; Bulent Gumusel; Howard Lippton
Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats.
The American journal of physiology 1998;274(4 Pt 2):H1218-29.
1998: Hunter C Champion; Philip J Kadowitz
R-(-)-alpha-methyl-histamine has nitric oxide-mediated vasodilator activity in the mesenteric vascular bed of the cat.
European journal of pharmacology 1998;343(2-3):209-16.
1998: Hunter C Champion; LS Estrada; L N Estrada; J G Filep; Philip J Kadowitz
Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ETA/ETB receptor antagonist, in the hind-limb vascular bed of the cat.
Canadian journal of physiology and pharmacology 1998;76(2):141-7.
1998: DG Lambert; Hunter C Champion; Philip J Kadowitz
Inhibitory effects of candesartan on responses to angiotensin peptides in the hindquarters vascular bed of the cat.
Canadian journal of physiology and pharmacology 1998;76(2):133-40.
1998: Anna S Belloni; Paola G Andreis; Gian Paolo Rossi; A Mingrino; Hunter C Champion; PJ Kadowitz; WA Murphy; DH Coy; Gastone G Nussdorfer
Inhibitory effect of adrenomedullin (ADM) on the aldosterone response of human adrenocortical cells to angiotensin-II: role of ADM(22-52)-sensitive receptors.
Life sciences 1998;63(26):2313-21.
1998: Hunter C Champion; Trinity J Bivalacqua; DE Friedman; James E Zadina; Abba J Kastin; Philip J Kadowitz
Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat.
Peptides 1998;19(9):1595-602.
1998: Anna S Belloni; V Meneghelli; Hunter C Champion; W A Murray; DH Coy; PJ Kadowitz; Gastone G Nussdorfer
Autoradiographic evidence that zona glomerulosa and capsular vessels of the human adrenal cortex are provided with different subtypes of adrenomedullin receptors.
Peptides 1998;19(9):1581-4.
1998: Hunter C Champion; Trinity J Bivalacqua; D G Lambert; S M McWilliams; J E Zadina; A J Kastin; Philip J Kadowitz
Endomorphin 1 and 2, the endogenous mu-opioid agonists, produce biphasic changes in systemic arterial pressure in the cat.
Life sciences 1998;63(9):PL131-6.
1998: Hunter C Champion; James E Zadina; Abba J Kastin; Philip J Kadowitz
Endomorphin 1 and 2 have vasodepressor activity in the anesthetized mouse.
Peptides 1998;19(5):925-9.
1998: Marc A Czapla; Hunter C Champion; James E Zadina; Abba J Kastin; Laszlo Hackler; LJ Ge; Philip J Kadowitz
Endomorphin 1 and 2, endogenous mu-opioid agonists, decrease systemic arterial pressure in the rat.
Life sciences 1998;62(13):PL175-9.
1998: Hunter C Champion; Marc A Czapla; Philip J Kadowitz
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
The American journal of physiology 1998;274(1 Pt 1):E115-23.
1997: E A Garrison; Hunter C Champion; Philip J Kadowitz
[Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.
The American journal of physiology 1997;273(6 Pt 1):E1059-64.
1997: Hunter C Champion; Donald L Akers; JA Santiago; DG Lambert; Dennis B McNamara; Philip J Kadowitz
Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat.
Molecular and cellular biochemistry 1997;176(1-2):5-11.
1997: Hunter C Champion; Philip J Kadowitz
Analysis of the effects of candesartan in the mesenteric vascular bed of the cat.
Hypertension 1997;30(5):1260-6.
1997: Hunter C Champion; R Wang; JA Santiago; William A Murphy; David H Coy; Philip J Kadowitz; Wayne J G Hellstrom
Comparison of responses to adrenomedullin and calcitonin gene-related peptide in the feline erection model.
Journal of andrology 1997;18(5):513-21.
1997: Bracken J Dewitt; Hunter C Champion; JR Marrone; Dennis B McNamara; Thomas D Giles; Stanley S Greenberg; Philip J Kadowitz
Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
The American journal of physiology 1997;273(3 Pt 1):L588-94.
1997: LS Estrada; Hunter C Champion; R Wang; M Rajasekaran; Wayne J G Hellstrom; B Aggarwal; Suresh C Sikka
Effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human sperm motility, viability and motion parameters.
International journal of andrology 1997;20(4):237-42.
1997: Hunter C Champion; Philip J Kadowitz
NO release and the opening of K+ATP channels mediate vasodilator responses to histamine in the cat.
The American journal of physiology 1997;273(2 Pt 2):H928-37.
1997: Hunter C Champion; R Wang; Wayne J G Hellstrom; Philip J Kadowitz
Nociceptin, a novel endogenous ligand for the ORL1 receptor, has potent erectile activity in the cat.
The American journal of physiology 1997;273(1 Pt 1):E214-9.
1997: Hunter C Champion; Philip J Kadowitz
Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.
The American journal of physiology 1997;273(1 Pt 2):R414-22.
1997: Hunter C Champion; James E Zadina; Abba J Kastin; Laszlo Hackler; LJ Ge; Philip J Kadowitz
The endogenous mu-opioid receptor agonists endomorphins 1 and 2 have novel hypotensive activity in the rabbit.
Biochemical and biophysical research communications 1997;235(3):567-70.
1997: Hunter C Champion; DG Lambert; S M McWilliams; Mrugeshkumar K Shah; William A Murphy; David H Coy; Philip J Kadowitz
Comparison of responses to rat and human adrenomedullin in the hindlimb vascular bed of the cat.
Regulatory peptides 1997;70(2-3):161-5.
1997: Hunter C Champion; Philip J Kadowitz
[Tyr1]-nociceptin, a novel nociceptin analog, decreases systemic arterial pressure by a naloxone-insensitive mechanism in the rat.
Biochemical and biophysical research communications 1997;234(2):309-12.
1997: Hunter C Champion; William A Murphy; David H Coy; Philip J Kadowitz
Proadrenomedullin NH2-terminal 20 peptide has direct vasodilator activity in the cat.
The American journal of physiology 1997;272(4 Pt 2):R1047-54.
1997: JA Santiago; Hunter C Champion; Philip J Kadowitz
T-kinin has endothelium-dependent vasodilator activity in the cat.
The American journal of physiology 1997;272(3 Pt 2):H1491-8.
1997: Hunter C Champion; R Wang; B B Shenassa; William A Murphy; David H Coy; Wayne J G Hellstrom; Philip J Kadowitz
Adrenomedullin induces penile erection in the cat.
European journal of pharmacology 1997;319(1):71-5.
1997: Hunter C Champion; James E Zadina; Abba J Kastin; Philip J Kadowitz
The endogenous mu-opioid agonists, endomorphin 1 and 2, have vasodilator activity in the hindquarters vascular bed of the rat.
Life sciences 1997;61(26):PL 409-15.
1997: Hunter C Champion; Philip J Kadowitz
[Tyr1]-nociceptin has naloxone-insensitive vasodilator activity in the hindquarters vascular bed of the rat.
Life sciences 1997;61(26):PL 403-8.
1997: Marc A Czapla; Hunter C Champion; Philip J Kadowitz
Decreases in systemic arterial and hindquarters perfusion pressure in response to nociceptin are not inhibited by naloxone in the rat.
Peptides 1997;18(8):1197-200.
1997: Hunter C Champion; James E Zadina; Abba J Kastin; Laszlo Hackler; LJ Ge; Philip J Kadowitz
Endomorphin 1 and 2, endogenous ligands for the mu-opioid receptor, decrease cardiac output, and total peripheral resistance in the rat.
Peptides 1997;18(9):1393-7.
1997: Hunter C Champion; JA Santiago; Marc A Czapla; Trinity J Bivalacqua; C Ilgenfritz; Philip J Kadowitz
Comparison of responses to T-kinin and bradykinin in the mesenteric vascular bed of the cat.
Peptides 1997;18(9):1357-64.
1997: Marc A Czapla; Hunter C Champion; Philip J Kadowitz
Nociceptin, an endogenous ligand for the ORL1 receptor, has vasodilator activity in the hindquarters vascular bed of the rat.
Peptides 1997;18(6):793-5.
1997: Hunter C Champion; Marc A Czapla; Philip J Kadowitz
Nociceptin, an endogenous ligand for the ORL1 receptor, decreases cardiac output and total peripheral resistance in the rat.
Peptides 1997;18(5):729-32.
1997: Hunter C Champion; Marc A Czapla; DE Friedman; DG Lambert; William A Murphy; David H Coy; Philip J Kadowitz
Tone-dependent vasodilator responses to proadrenomedullin NH2-terminal 20 peptide in the hindquarters vascular bed of the rat.
Peptides 1997;18(4):513-9.
1997: Hunter C Champion; DE Friedman; DG Lambert; William A Murphy; David H Coy; Philip J Kadowitz
Adrenomedullin (16-31) has pressor activity in the rat but not the cat.
Peptides 1997;18(1):133-6.
1997: Hunter C Champion; Philip J Kadowitz
Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat.
Life sciences 1997;60(16):PL 241-5.
1997: Rebecca Fry; Hunter C Champion; T C Lawrence; William A Murphy; David H Coy; Philip J Kadowitz
Proadrenomedullin NH2-terminal peptide (PAMP)(12-20) has vasodepressor activity in the rat and cat.
Life sciences 1997;60(10):PL161-7.
1997: Hunter C Champion; JA Santiago; William A Murphy; David H Coy; Philip J Kadowitz
Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat.
The American journal of physiology 1997;272(1 Pt 2):R234-42.
1996: Hunter C Champion; JA Santiago; E A Garrison; D Y Cheng; David H Coy; William A Murphy; Robert J Ascuitto; Nancy Ross-Ascuitto; Dennis B McNamara; Philip J Kadowitz
Analysis of cardiovascular responses to PACAP-27, PACAP-38, and vasoactive intestinal polypeptide.
Annals of the New York Academy of Sciences 1996;805():429-41; discussion 442.
1996: Bracken J Dewitt; D Y Cheng; T J McMahon; J R Marrone; Hunter C Champion; P J Kandowitz
Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation.
The American journal of physiology 1996;271(6 Pt 1):L924-31.
1996: Hunter C Champion; Rebecca Fry; William A Murphy; David H Coy; Philip J Kadowitz
Catecholamine release mediates pressor effects of adrenomedullin-(15-22) in the rat.
Hypertension 1996;28(6):1041-6.
1996: Hunter C Champion; E A Garrison; L S Estrada; J M Potter; Philip J Kadowitz
Analysis of responses to angiotensin I and angiotensin I-(3-10) in the mesenteric vascular bed of the cat.
European journal of pharmacology 1996;309(3):251-9.
1996: Hunter C Champion; C C Erickson; M L Simoneaux; Trinity J Bivalacqua; William A Murphy; David H Coy; Philip J Kadowitz
Proadrenomedullin NH2-terminal 20 peptide has cAMP-mediated vasodilator activity in the mesenteric vascular bed of the cat.
Peptides 1996;17(8):1379-87.
1996: Hunter C Champion; C D Duperier; W E Fitzgerald; DG Lambert; William A Murphy; David H Coy; Philip J Kadowitz
[MPR14]-rADM(14-50), a novel analog of adrenomedullin, possesses potent vasodilator activity in the hindlimb vascular bed of the cat.
Life sciences 1996;59(1):PL1-7.
1995: JA Santiago; E A Garrison; Hunter C Champion; R E Smith; O Del Rio; Philip J Kadowitz
Analysis of responses to kallidin, DABK, and DAK in feline hindlimb vascular bed.
The American journal of physiology 1995;269(6 Pt 2):H2057-64.
1995: JA Santiago; E Garrison; W L Purnell; R E Smith; Hunter C Champion; David H Coy; William A Murphy; Philip J Kadowitz
Comparison of responses to adrenomedullin and adrenomedullin analogs in the mesenteric vascular bed of the cat.
European journal of pharmacology 1995;272(1):115-8.