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Irene Ann Chen

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Publications

TOP 3
Aaron M Leconte; Benjamin Allen; Irene Ann Chen; Bryan C Dickinson; David D Yang; David R Liu
A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.
Kevin Leu; Jesus-Mario Luevano; Benedikt Obermayer; Clemens Richert; Rebecca M Turk-MacLeod; Caterina Yuan; Eric Chen; Ulrich Gerland; Eric Kervio; Irene Ann Chen
Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.
Irene Ann Chen; Martin A Nowak
From prelife to life: how chemical kinetics become evolutionary dynamics.

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All Publications

2013: Aaron M Leconte; Benjamin Allen; Irene Ann Chen; Bryan C Dickinson; David D Yang; David R Liu
A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.
Biochemistry 2013;52(8):1490-9.
2013: Kevin Leu; Jesus-Mario Luevano; Benedikt Obermayer; Clemens Richert; Rebecca M Turk-MacLeod; Caterina Yuan; Eric Chen; Ulrich Gerland; Eric Kervio; Irene Ann Chen
Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.
Journal of the American Chemical Society 2013;135(1):354-66.
2012: Irene Ann Chen; Martin A Nowak
From prelife to life: how chemical kinetics become evolutionary dynamics.
Accounts of chemical research 2012;45(12):2088-96.
2012: Nilesh Vaidya; Ramon Xulvi-Brunet; Irene Ann Chen; Eric J Hayden; Michael L Manapat; Niles Lehman
Spontaneous network formation among cooperative RNA replicators.
Nature 2012;491(7422):72-7.
2012: Julien Derr; Isaac Joseph; Kevin Leu; Michael L Manapat; Martin A Nowak; Sudha Rajamani; Ramon Xulvi-Brunet; Irene Ann Chen
Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences.
Nucleic acids research 2012;40(10):4711-22.
2011: Kevin Leu; Benedikt Obermayer; Sudha Rajamani; Ulrich Gerland; Irene Ann Chen
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA.
Nucleic acids research 2011;39(18):8135-47.
2011: Abraham Lin; Jose Jimenez; Julien Derr; Pedro Vera; Michael L Manapat; Kevin M Esvelt; Laura Villanueva; David R. Liu; Irene Ann Chen
Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model.
PloS one 2011;6(5):e19991.
2010: Irene Ann Chen; Michael Schindlinger
Quadruplet codons: one small step for a ribosome, one giant leap for proteins: an expanded genetic code could address fundamental questions about algorithmic information, biological function, and the origins of life.
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(8):650-4.
2010: Irene Ann Chen; Peter Walde
From self-assembled vesicles to protocells.
Cold Spring Harbor perspectives in biology 2010;2(7):a002170.
2010: Sudha Rajamani; Justin K Ichida; Tibor Antal; Douglas A Treco; Kevin Leu; Martin A Nowak; Jack W Szostak; Irene Ann Chen
Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.
Journal of the American Chemical Society 2010;132(16):5880-5.
2010: Michael L Manapat; Irene Ann Chen; Martin A Nowak
The basic reproductive ratio of life.
Journal of theoretical biology 2010;263(3):317-27.
2009: Irene Ann Chen
Cell division: breaking up is easy to do.
Current biology : CB 2009;19(8):R327-8.
2006: Irene Ann Chen
GE Prize-winning essay. The emergence of cells during the origin of life.
Science (New York, N.Y.) 2006;314(5805):1558-9.
2005: Shelly M Fujikawa; Irene Ann Chen; Jack W Szostak
Shrink-wrap vesicles.
Langmuir : the ACS journal of surfaces and colloids 2005;21(26):12124-9.
2005: Irene Ann Chen; Kourosh Salehi-Ashtiani; Jack W Szostak
RNA catalysis in model protocell vesicles.
Journal of the American Chemical Society 2005;127(38):13213-9.
2004: Irene Ann Chen; Richard W Roberts; Jack W Szostak
The emergence of competition between model protocells.
Science (New York, N.Y.) 2004;305(5689):1474-6.
2004: Irene Ann Chen; Jack W Szostak
A kinetic study of the growth of fatty acid vesicles.
Biophysical journal 2004;87(2):988-98.
2004: Irene Ann Chen; Jack W Szostak
Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):7965-70.
2003: Aaron F Straight; Amy Cheung; John Limouze; Irene Ann Chen; Nick J Westwood; James R Sellers; Timothy J Mitchison
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.
Science (New York, N.Y.) 2003;299(5613):1743-7.
2000: Peter Kast; C Grisostomi; Irene Ann Chen; Sheng Li; Ute Krengel; Y Xue; Donald Hilvert
A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
The Journal of biological chemistry 2000;275(47):36832-8.