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Francis Ka-Ming Chan

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Publications

TOP 3
Francis Ka-Ming Chan; Kenta Moriwaki; María José De Rosa
Detection of necrosis by release of lactate dehydrogenase activity.
Francis Ka-Ming Chan
Fueling the flames: Mammalian programmed necrosis in inflammatory diseases.
Jixi Li; Ann McDermott; Thomas McQuade; David Moquin; Kenta Moriwaki; Johanna Napetschnig; Ansgar B Siemer; Thomas Walz; Francis Ka-Ming Chan; Ermelinda Damko; Yu-Shan Hsiao; Hao Wu
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.

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All Publications

2013: Francis Ka-Ming Chan; Kenta Moriwaki; María José De Rosa
Detection of necrosis by release of lactate dehydrogenase activity.
Methods in molecular biology (Clifton, N.J.) 2013;979():65-70.
2012: Francis Ka-Ming Chan
Fueling the flames: Mammalian programmed necrosis in inflammatory diseases.
Cold Spring Harbor perspectives in biology 2012;4(11):.
2012: Jixi Li; Ann McDermott; Thomas McQuade; David Moquin; Kenta Moriwaki; Johanna Napetschnig; Ansgar B Siemer; Thomas Walz; Francis Ka-Ming Chan; Ermelinda Damko; Yu-Shan Hsiao; Hao Wu
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.
Cell 2012;150(2):339-50.
2012: Francis Ka-Ming Chan; Eric H Baehrecke
RIP3 finds partners in crime.
Cell 2012;148(1-2):17-8.
2011: Haibing Zhang; Xiaohui Zhou; Thomas McQuade; Jinghe Li; Francis Ka-Ming Chan; Jianke Zhang
Functional complementation between FADD and RIP1 in embryos and lymphocytes.
Nature 2011;471(7338):373-6.
2011: YoungSik Cho; Thomas McQuade; Haibing Zhang; Jianke Zhang; Francis Ka-Ming Chan
RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation.
PloS one 2011;6(8):e23209.
2011: Youngsik Cho; Sreerupa Challa; Francis Ka-Ming Chan
A RNA interference screen identifies RIP3 as an essential inducer of TNF-induced programmed necrosis.
Advances in experimental medicine and biology 2011;691():589-93.
2010: Sreerupa Challa; Melissa Woelfel; Melissa Guildford; David Moquin; Francis Ka-Ming Chan
Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection.
Journal of virology 2010;84(20):10467-76.
2010: Sreerupa Challa; Francis Ka-Ming Chan
Going up in flames: necrotic cell injury and inflammatory diseases.
Cellular and molecular life sciences : CMLS 2010;67(19):3241-53.
2010: David Moquin; Francis Ka-Ming Chan
The molecular regulation of programmed necrotic cell injury.
Trends in biochemical sciences 2010;35(8):434-41.
2010: Young Sik Cho; Seung Yeon Park; Hee Suk Shin; Francis Ka-Ming Chan
Physiological consequences of programmed necrosis, an alternative form of cell demise.
Molecules and cells 2010;29(4):327-32.
2009: Young Sik Cho; Sreerupa Challa; David Moquin; Ryan Genga; Tathagat Dutta Ray; Melissa Guildford; Francis Ka-Ming Chan
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
Cell 2009;137(6):1112-23.
2007: Francis Ka-Ming Chan
Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling.
Cytokine 2007;37(2):101-7.
2006: Melissa Woelfel; Jacqueline Bixby; Michael A Brehm; Francis Ka-Ming Chan
Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3814-20.
2005: Lauren Clancy; Karen Mruk; Kristina Archer; Melissa Woelfel; Juthathip Mongkolsapaya; Gavin Screaton; Michael J Lenardo; Francis Ka-Ming Chan
Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18099-104.
2005: Guo-Min Deng; Lixin Zheng; Francis Ka-Ming Chan; Michael J Lenardo
Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors.
Nature medicine 2005;11(10):1066-72.
2004: Francis Ka-Ming Chan
Monitoring molecular interactions in living cells using flow cytometric analysis of fluorescence resonance energy transfer.
Methods in molecular biology (Clifton, N.J.) 2004;261():371-82.
2004: Francis Ka-Ming Chan; Kevin L Holmes
Flow cytometric analysis of fluorescence resonance energy transfer: a tool for high-throughput screening of molecular interactions in living cells.
Methods in molecular biology (Clifton, N.J.) 2004;263():281-92.
2003: Francis Ka-Ming Chan; Joanna L Shisler; Jacqueline G Bixby; Martin Felices; Lixin Zheng; Michael Appel; Jan Orenstein; Bernard Moss; Michael J Lenardo
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses.
The Journal of biological chemistry 2003;278(51):51613-21.
2001: Francis Ka-Ming Chan; Richard Siegel; David Zacharias; R Swofford; K L Holmes; Roger Y Tsien; Michael J Lenardo
Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein.
Cytometry 2001;44(4):361-8.
2000: Richard Siegel; Francis Ka-Ming Chan; H J Chun; Michael J Lenardo
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity.
Nature immunology 2000;1(6):469-74.
2000: Richard Siegel; J K Frederiksen; David Zacharias; Francis Ka-Ming Chan; M Johnson; D Lynch; Roger Y Tsien; Michael J Lenardo
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.
Science (New York, N.Y.) 2000;288(5475):2354-7.
2000: Francis Ka-Ming Chan; H J Chun; Lixin Zheng; Richard Siegel; K L Bui; Michael J Lenardo
A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling.
Science (New York, N.Y.) 2000;288(5475):2351-4.
2000: Richard Siegel; Francis Ka-Ming Chan; David Zacharias; R Swofford; K L Holmes; Roger Y Tsien; Michael J Lenardo
Measurement of molecular interactions in living cells by fluorescence resonance energy transfer between variants of the green fluorescent protein.
Science's STKE : signal transduction knowledge environment 2000;2000(38):pl1.
2000: Francis Ka-Ming Chan; Michael J Lenardo
A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes.
European journal of immunology 2000;30(2):652-60.
1999: Juehu Wang; Lixin Zheng; Adrian A Lobito; Francis Ka-Ming Chan; Janet Dale; M Sneller; X Yao; Jennifer M Puck; Stephen E Straus; Michael J Lenardo
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.
Cell 1999;98(1):47-58.