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Hak-Kim Chan

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Adam Guastella; Ian B Hickie; Gail Alvares; Hak-Kim Chan; Timothy F Chen; Richard B Banati
Unitary hormonal models, peripheral markers, and evaluation of response to drug: A response to Weisman and Feldman.
Adam Guastella; Ian B Hickie; Margaret M McGuinness; Melissa Otis; Elizabeth A Woods; Hak-Kim Chan; Timothy F Chen; Hannah M Disinger; Richard B Banati
Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research.
Qi Tony Zhou; Mauro Citterio; Patricia Tang; Zhenbo Tong; Runyu Yang; Hak-Kim Chan
Effect of device design on the aerosolization of a carrier-based dry powder inhaler--a case study on Aerolizer(®) Foradile (®).

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2013: Adam Guastella; Ian B Hickie; Gail Alvares; Hak-Kim Chan; Timothy F Chen; Richard B Banati
Unitary hormonal models, peripheral markers, and evaluation of response to drug: A response to Weisman and Feldman.
Psychoneuroendocrinology 2013;38(5):627-8.
2013: Adam Guastella; Ian B Hickie; Margaret M McGuinness; Melissa Otis; Elizabeth A Woods; Hak-Kim Chan; Timothy F Chen; Hannah M Disinger; Richard B Banati
Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research.
Psychoneuroendocrinology 2013;38(5):612-25.
2013: Qi Tony Zhou; Mauro Citterio; Patricia Tang; Zhenbo Tong; Runyu Yang; Hak-Kim Chan
Effect of device design on the aerosolization of a carrier-based dry powder inhaler--a case study on Aerolizer(®) Foradile (®).
The AAPS journal 2013;15(2):511-22.
2012: Sunalene G Devadason; Sabine Haeussermann; Claudius Kietzig; Philip J Kuehl; Stephen Newman; Knut Sommerer; Hak-Kim Chan; Glyn Taylor
Validation of radiolabeling of drug formulations for aerosol deposition assessment of orally inhaled products.
Journal of aerosol medicine and pulmonary drug delivery 2012;25 Suppl 1():S6-9.
2012: John Fleming; Philip J Kuehl; Beth L Laube; Dale L Bailey; Hak-Kim Chan; Joy Conway; Stephen Newman
Standardization of techniques for using single-photon emission computed tomography (SPECT) for aerosol deposition assessment of orally inhaled products.
Journal of aerosol medicine and pulmonary drug delivery 2012;25 Suppl 1():S29-51.
2012: John Gar Yan Chan; Daniela Traini; Paul M Young; Hak-Kim Chan; Philip Chi Lip Kwok
Delivery of high solubility polyols by vibrating mesh nebulizer to enhance mucociliary clearance.
Journal of aerosol medicine and pulmonary drug delivery 2012;25(5):297-305.
2012: Patricia Tang; Zhenbo Tong; Runyu Yang; Philip Chi Lip Kwok; Judy Agnes Raper; Hak-Kim Chan
Does the United States Pharmacopeia throat introduce de-agglomeration of carrier-free powder from inhalers?
Pharmaceutical research 2012;29(7):1797-807.
2012: Suzanne M D'Addio; Philip Chi Lip Kwok; Robert K Prud'homme; John Gar Yan Chan; Hak-Kim Chan
Constant size, variable density aerosol particles by ultrasonic spray freeze drying.
International journal of pharmaceutics 2012;427(2):185-91.
2012: William Wong; Hak-Kim Chan; David F Fletcher; Daniela Traini; Paul M Young
The use of computational approaches in inhaler development.
Advanced drug delivery reviews 2012;64(4):312-22.
2012: Jenny Ka-Wing Lam; Wanling Liang; Hak-Kim Chan
Pulmonary delivery of therapeutic siRNA.
Advanced drug delivery reviews 2012;64(1):1-15.
2011: Keishi Yamasaki; Kaori Fukushige; Philip Chi Lip Kwok; Robert K Prud'homme; Hak-Kim Chan
Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former.
International journal of pharmaceutics 2011;420(1):34-42.
2011: William Wong; Hak-Kim Chan; John Crapper; David F Fletcher; Daniela Traini; Paul M Young
Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of the influence of grid structures for agglomerated systems.
Journal of pharmaceutical sciences 2011;100(11):4710-21.
2011: William Wong; David F Fletcher; Daniela Traini; Hak-Kim Chan; John Crapper; Paul M Young
Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of impaction effects for agglomerated systems.
Journal of pharmaceutical sciences 2011;100(7):2744-54.
2011: John Gar Yan Chan; Philip Chi Lip Kwok; Paul M Young; Hak-Kim Chan; Daniela Traini
Mannitol delivery by vibrating mesh nebulisation for enhancing mucociliary clearance.
Journal of pharmaceutical sciences 2011;100(7):2693-702.
2011: Hak-Kim Chan
Nanodrug particles and nanoformulations for drug delivery.
Advanced drug delivery reviews 2011;63(6):405.
2011: Hak-Kim Chan; Philip Chi Lip Kwok
Production methods for nanodrug particles using the bottom-up approach.
Advanced drug delivery reviews 2011;63(6):406-16.
2011: Jian Zhang; Libo Wu; Hak-Kim Chan; Wiwik Watanabe
Formation, characterization, and fate of inhaled drug nanoparticles.
Advanced drug delivery reviews 2011;63(6):441-55.
2011: Philip Chi Lip Kwok; Amolnat Tunsirikongkon; William Glover; Hak-Kim Chan
Formation of protein nano-matrix particles with controlled surface architecture for respiratory drug delivery.
Pharmaceutical research 2011;28(4):788-96.
2011: Patricia Tang; Hak-Kim Chan; Dorrilyn Rajbhandari; Paul Phipps
Method to introduce mannitol powder to intubated patients to improve sputum clearance.
Journal of aerosol medicine and pulmonary drug delivery 2011;24(1):1-9.
2011: Sie Huey Lee; Desmond Heng; Wai Kiong Ng; Hak-Kim Chan; Reginald B H Tan
Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy.
International journal of pharmaceutics 2011;403(1-2):192-200.
2011: Wipaporn Rojanarat; Hak-Kim Chan; Narumon Changsan; Sirirat Pinsuwan; Ekawat Tawithong; Teerapol Srichana
Isoniazid proliposome powders for inhalation-preparation, characterization and cell culture studies.
International journal of molecular sciences 2011;12(7):4414-34.
2010: Jeffry G Weers; John Bell; Hak-Kim Chan; David Cipolla; Craig Dunbar; Anthony J Hickey; Ian J Smith
Pulmonary formulations: what remains to be done?
Journal of aerosol medicine and pulmonary drug delivery 2010;23 Suppl 2():S5-23.
2010: David Cipolla; Hak-Kim Chan; Jeffrey Schuster; Dino Farina
Personalizing aerosol medicine: development of delivery systems tailored to the individual.
Therapeutic delivery 2010;1(5):667-82.
2010: Santoso Adi; Zhenbo Tong; Hak-Kim Chan; Runyu Yang; Aibing Yu
Impact angles as an alternative way to improve aerosolisation of powders for inhalation?
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;41(2):320-7.
2010: William Wong; David F Fletcher; Daniela Traini; Hak-Kim Chan; John Crapper; Paul M Young
Particle aerosolisation and break-up in dry powder inhalers 1: evaluation and modelling of venturi effects for agglomerated systems.
Pharmaceutical research 2010;27(7):1367-76.
2010: Susan Hoe; Daniela Traini; Hak-Kim Chan; Paul M Young
The contribution of different formulation components on the aerosol charge in carrier-based dry powder inhaler systems.
Pharmaceutical research 2010;27(7):1325-36.
2010: Handoko Adi; Paul M Young; Hak-Kim Chan; Helen Agus; Daniela Traini
Co-spray-dried mannitol-ciprofloxacin dry powder inhaler formulation for cystic fibrosis and chronic obstructive pulmonary disease.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(3):239-47.
2010: Philip Chi Lip Kwok; Sebastiaan J Trietsch; Michiko Kumon; Hak-Kim Chan
Electrostatic charge characteristics of jet nebulized aerosols.
Journal of aerosol medicine and pulmonary drug delivery 2010;23(3):149-59.
2010: Handoko Adi; Philip Chi Lip Kwok; John Crapper; Paul M Young; Daniela Traini; Hak-Kim Chan
Does electrostatic charge affect powder aerosolisation?
Journal of pharmaceutical sciences 2010;99(5):2455-61.
2010: Michiko Kumon; Philip Chi Lip Kwok; Handoko Adi; Desmond Heng; Hak-Kim Chan
Can low-dose combination products for inhalation be formulated in single crystalline particles?
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(1):16-24.
2010: Syed Anuar Faua'ad Syed Muhammad; Tim Langrish; Patricia Tang; Handoko Adi; Hak-Kim Chan; Sergei G Kazarian; Fariba Dehghani
A novel method for the production of crystalline micronised particles.
International journal of pharmaceutics 2010;388(1-2):114-22.
2010: William Wong; John Crapper; Hak-Kim Chan; Daniela Traini; Paul M Young
Pharmacopeial methodologies for determining aerodynamic mass distributions of ultra-high dose inhaler medicines.
Journal of pharmaceutical and biomedical analysis 2010;51(4):853-7.
2010: Handoko Adi; Hak-Kim Chan; Rania Salama; Paul M Young; Daniela Traini
Controlled release antibiotics for dry powder lung delivery.
Drug development and industrial pharmacy 2010;36(1):119-26.
2009: Philip Chi Lip Kwok; Hak-Kim Chan
Electrostatics of pharmaceutical inhalation aerosols.
The Journal of pharmacy and pharmacology 2009;61(12):1587-99.
2009: Susan Hoe; Daniela Traini; Hak-Kim Chan; Paul M Young
The influence of flow rate on the aerosol deposition profile and electrostatic charge of single and combination metered dose inhalers.
Pharmaceutical research 2009;26(12):2639-46.
2009: Susan Hoe; Daniela Traini; Hak-Kim Chan; Paul M Young
Measuring charge and mass distributions in dry powder inhalers using the electrical Next Generation Impactor (eNGI).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(2):88-94.
2009: Rania O Salama; Leigh Ladd; Hak-Kim Chan; Daniela Traini; Paul M Young
Development of an in vivo ovine dry powder inhalation model for the evaluation of conventional and controlled release microparticles.
The AAPS journal 2009;11(3):465-8.
2009: Rania Salama; Daniela Traini; Hak-Kim Chan; Paul M Young
Recent advances in controlled release pulmonary therapy.
Current drug delivery 2009;6(4):404-14.
2009: Rania O Salama; Daniela Traini; Hak-Kim Chan; Adrian Sung; Alaina J Ammit; Paul M Young
Preparation and evaluation of controlled release microparticles for respiratory protein therapy.
Journal of pharmaceutical sciences 2009;98(8):2709-17.
2009: Paul M Young; Philip Kwok; Handoko Adi; Hak-Kim Chan; Daniela Traini
Lactose composite carriers for respiratory delivery.
Pharmaceutical research 2009;26(4):802-10.
2009: P Tang; Hak-Kim Chan; Herbert Chiou; K Ogawa; M D Jones; H Adi; G Buckton; R K Prud'homme; Judy A Raper
Characterisation and aerosolisation of mannitol particles produced via confined liquid impinging jets.
International journal of pharmaceutics 2009;367(1-2):51-7.
2009: Susan Hoe; Paul M Young; Hak-Kim Chan; Daniela Traini
Introduction of the electrical next generation impactor (eNGI) and investigation of its capabilities for the study of pressurized metered dose inhalers.
Pharmaceutical research 2009;26(2):431-7.
2009: Narumon Changsan; Hak-Kim Chan; Frances Separovic; Teerapol Srichana
Physicochemical characterization and stability of rifampicin liposome dry powder formulations for inhalation.
Journal of pharmaceutical sciences 2009;98(2):628-39.
2008: Santoso Adi; Handoko Adi; Hak-Kim Chan; Paul M Young; Daniela Traini; Runyu Yang; Aibing Yu
Scanning white-light interferometry as a novel technique to quantify the surface roughness of micron-sized particles for inhalation.
Langmuir : the ACS journal of surfaces and colloids 2008;24(19):11307-12.
2008: Santoso Adi; Handoko Adi; Patricia Tang; Daniela Traini; Hak-Kim Chan; Paul M Young
Micro-particle corrugation, adhesion and inhalation aerosol efficiency.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(1-2):12-8.
2008: Rania O Salama; Daniela Traini; Hak-Kim Chan; Paul M Young
Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 2: evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(1):145-52.
2008: Hak-Kim Chan
What is the role of particle morphology in pharmaceutical powder aerosols?
Expert opinion on drug delivery 2008;5(8):909-14.
2008: Handoko Adi; Paul M Young; Hak-Kim Chan; Peter Stewart; Helen Agus; Daniela Traini
Cospray dried antibiotics for dry powder lung delivery.
Journal of pharmaceutical sciences 2008;97(8):3356-66.
2008: Desmond Heng; David J Cutler; Hak-Kim Chan; Jimmy Yun; Judy A Raper
Dissolution kinetic behavior of drug nanoparticles and their conformity to the diffusion model.
Langmuir : the ACS journal of surfaces and colloids 2008;24(14):7538-44.
2008: Desmond Heng; David J Cutler; Hak-Kim Chan; Jimmy Yun; Judy A Raper
What is a suitable dissolution method for drug nanoparticles?
Pharmaceutical research 2008;25(7):1696-701.
2008: Handoko Adi; Daniela Traini; Hak-Kim Chan; Paul M Young
The influence of drug morphology on aerosolisation efficiency of dry powder inhaler formulations.
Journal of pharmaceutical sciences 2008;97(7):2780-8.
2008: Rania Salama; Susan Hoe; Hak-Kim Chan; Daniela Traini; Paul M Young
Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 1: influence of polymer concentration on physical and in vitro characteristics.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(2):486-95.
2008: Stephen P Newman; Hak-Kim Chan
In vitro/in vivo comparisons in pulmonary drug delivery.
Journal of aerosol medicine and pulmonary drug delivery 2008;21(1):77-84.
2008: William Glover; Hak-Kim Chan; Stefan Eberl; Evangelia Daviskas; Jordan Verschuer
Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers.
International journal of pharmaceutics 2008;349(1-2):314-22.
2008: Tingting Hu; Herbert Chiou; Hak-Kim Chan; Jian-Feng Chen; Jimmy Yun
Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation.
Journal of pharmaceutical sciences 2008;97(2):944-9.
2008: Philip Chi Lip Kwok; Hak-Kim Chan
Effect of relative humidity on the electrostatic charge properties of dry powder inhaler aerosols.
Pharmaceutical research 2008;25(2):277-88.
2008: Herbert Chiou; Hak-Kim Chan; Robert K Prud'homme; Judy A Raper
Evaluation on the use of confined liquid impinging jets for the synthesis of nanodrug particles.
Drug development and industrial pharmacy 2008;34(1):59-64.
2007: Desmond Heng; Patricia Tang; Julie M Cairney; Hak-Kim Chan; David J Cutler; Rania Salama; Jimmy Yun
Focused-ion-beam milling: a novel approach to probing the interior of particles used for inhalation aerosols.
Pharmaceutical research 2007;24(9):1608-17.
2007: Matthew S Coates; Hak-Kim Chan; David F Fletcher; Herbert Chiou
Influence of mouthpiece geometry on the aerosol delivery performance of a dry powder inhaler.
Pharmaceutical research 2007;24(8):1450-6.
2007: Paul M Young; Hak-Kim Chan; Herbert Chiou; Stephen Edge; Terence H S Tee; Daniela Traini
The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance.
Journal of pharmaceutical sciences 2007;96(5):1331-41.
2007: Paul M Young; Adrian Sung; Daniela Traini; Philip Kwok; Herbert Chiou; Hak-Kim Chan
Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems.
Pharmaceutical research 2007;24(5):963-70.
2007: Herbert Chiou; Li Li; Tingting Hu; Hak-Kim Chan; Jian-Feng Chen; Jimmy Yun
Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitation.
International journal of pharmaceutics 2007;331(1):93-8.
2007: Jolyon Mitchell; Steve Newman; Hak-Kim Chan
In vitro and in vivo aspects of cascade impactor tests and inhaler performance: a review.
AAPS PharmSciTech 2007;8(4):E110.
2007: Abolghasem Jouyban; Sh Soltanpour; S Soltani; Hak-Kim Chan; William E Acree
Solubility prediction of drugs in water-cosolvent mixtures using Abraham solvation parameters.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2007;10(3):263-77.
2007: Paul M Young; Herbert Chiou; Terrance Tee; Daniela Traini; Hak-Kim Chan; Frank Thielmann; Dan Burnett
The use of organic vapor sorption to determine low levels of amorphous content in processed pharmaceutical powders.
Drug development and industrial pharmacy 2007;33(1):91-7.
2006: Abolghasem Jouyban; Maryam Khoubnasabjafari; Hak-Kim Chan; William E Acree
Mathematical representation of solubility of amino acids in binary aqueous-organic solvent mixtures at various temperatures using the Jouyban-Acree model.
Die Pharmazie 2006;61(9):789-92.
2006: Matthew S Coates; Hak-Kim Chan; David F Fletcher; Judy A Raper
Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 2: Air inlet size.
Journal of pharmaceutical sciences 2006;95(6):1382-92.
2006: Abolghasem Jouyban; Nora Yat Knork Chew; Hak-Kim Chan; Maryam Khoubnasabjafari; William E Acree
Solubility prediction of salicylic acid in water-ethanol-propylene glycol mixtures using the Jouyban-Acree model.
Die Pharmazie 2006;61(4):318-21.
2006: Abolghasem Jouyban; Hak-Kim Chan; Nora Yat Knork Chew; Maryam Khoubnasabjafari; William E Acree
Solubility prediction of paracetamol in binary and ternary solvent mixtures using Jouyban-Acree model.
Chemical & pharmaceutical bulletin 2006;54(4):428-31.
2006: William Glover; Hak-Kim Chan; Stefan Eberl; Evangelia Daviskas; Sandra Anderson
Lung deposition of mannitol powder aerosol in healthy subjects.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(4):522-32.
2006: Hak-Kim Chan
Dry powder aerosol delivery systems: current and future research directions.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(1):21-7.
2006: Stefan Eberl; Hak-Kim Chan; Evangelia Daviskas
SPECT Imaging for Radioaerosol Deposition and Clearance Studies.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(1):8-20.
2006: Hak-Kim Chan; Herbert Chiou; Philip Kwok
The 15th International Society of Aerosols in Medicine Congress. Perth, Australia, 14-18 March 2005.
Expert opinion on drug delivery 2006;3(1):163-7.
2005: Philip Chi Lip Kwok; William Glover; Hak-Kim Chan
Electrostatic charge characteristics of aerosols produced from metered dose inhalers.
Journal of pharmaceutical sciences 2005;94(12):2789-99.
2005: Nora Y K Chew; Boris Y Shekunov; Henry H Y Tong; Albert H L Chow; Charles Savage; James Wu; Hak-Kim Chan
Effect of amino acids on the dispersion of disodium cromoglycate powders.
Journal of pharmaceutical sciences 2005;94(10):2289-300.
2005: Heikki O Koskela; Ruth Martens; John D Brannan; Sandra D Anderson; Jörg D Leuppi; Hak-Kim Chan
Dissociation in the effect of nedocromil on mannitol-induced cough or bronchoconstriction in asthmatic subjects.
Respirology (Carlton, Vic.) 2005;10(4):442-8.
2005: Matthew S Coates; Hak-Kim Chan; David F Fletcher; Judy A Raper
Influence of air flow on the performance of a dry powder inhaler using computational and experimental analyses.
Pharmaceutical research 2005;22(9):1445-53.
2005: Matthew S Coates; David F Fletcher; Hak-Kim Chan; Judy A Raper
The role of capsule on the performance of a dry powder inhaler using computational and experimental analyses.
Pharmaceutical research 2005;22(6):923-32.
2005: Abolghasem Jouyban; Nora Yat Knork Chew; Hak-Kim Chan; Mohammad Sabour; William E Acree
A unified cosolvency model for calculating solute solubility in mixed solvents.
Chemical & pharmaceutical bulletin 2005;53(6):634-7.
2005: Abolghasem Jouyban; Maryam Khoubnasabjafari; Hak-Kim Chan
Modeling the entrainer effects on solubility of solutes in supercritical carbon dioxide.
Chemical & pharmaceutical bulletin 2005;53(3):290-5.
2005: Nora Y K Chew; Patricia Tang; Hak-Kim Chan; Judy A Raper
How much particle surface corrugation is sufficient to improve aerosol performance of powders?
Pharmaceutical research 2005;22(1):148-52.
2005: Evangelia Daviskas; Sandra D Anderson; Kerry Gomes; Peter Briffa; Belinda Cochrane; Hak-Kim Chan; Iven H Young; Bruce K Rubin
Inhaled mannitol for the treatment of mucociliary dysfunction in patients with bronchiectasis: effect on lung function, health status and sputum.
Respirology (Carlton, Vic.) 2005;10(1):46-56.
2005: Jörg D Leuppi; Ryan Tandjung; Sandra D Anderson; Daiana Stolz; Martin H Brutsche; Roland Bingisser; André P Perruchoud; Christian Surber; Andreas Knoblauch; Morgan Andersson; Lennart Greiff; Hak-Kim Chan; Michael Tamm
Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of concept.
Pulmonary pharmacology & therapeutics 2005;18(2):83-8.
2004: Matthew S Coates; David F Fletcher; Hak-Kim Chan; Judy A Raper
Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 1: Grid structure and mouthpiece length.
Journal of pharmaceutical sciences 2004;93(11):2863-76.
2004: Nora Y K Chew; Helen K Reddel; Sinthia Z Bosnic-Anticevich; Hak-Kim Chan
Effect of mouthpiece washing on aerosol performance of CFC-free Ventolin.
The Journal of asthma : official journal of the Association for the Care of Asthma 2004;41(7):721-7.
2004: Heikki O Koskela; Liisa Hyvärinen; John D Brannan; Hak-Kim Chan; Sandra D Anderson
Coughing during mannitol challenge is associated with asthma.
Chest 2004;125(6):1985-92.
2004: Hak-Kim Chan; Andrew R Clark; Jane C Feeley; Mei-Chang Kuo; S Russ Lehrman; Katherine Pikal-Cleland; Danforth Miller; Reinhard Vehring; David Lechuga-Ballesteros
Physical stability of salmon calcitonin spray-dried powders for inhalation.
Journal of pharmaceutical sciences 2004;93(3):792-804.
2004: Abolghasem Jouyban; Hak-Kim Chan; S Romero; Maryam Khoubnasabjafari; P Bustamante
Solubility prediction in water-ethanol mixtures based on the excess free energy approach using a minimum number of experimental data.
Die Pharmazie 2004;59(2):117-20.
2004: Abolghasem Jouyban; Shahla Soltanpour; Hak-Kim Chan
A simple relationship between dielectric constant of mixed solvents with solvent composition and temperature.
International journal of pharmaceutics 2004;269(2):353-60.
2004: Jian-Feng Chen; Min-Yi Zhou; Lei Shao; Yu-Yong Wang; Jimmy Yun; Nora Y K Chew; Hak-Kim Chan
Feasibility of preparing nanodrugs by high-gravity reactive precipitation.
International journal of pharmaceutics 2004;269(1):267-74.
2003: Rana T Bustami; Hak-Kim Chan; Theresa Sweeney; Fariba Dehghani; Neil R Foster
Generation of fine powders of recombinant human deoxyribonuclease using the aerosol solvent extraction system.
Pharmaceutical research 2003;20(12):2028-35.
2003: Heikki O Koskela; Liisa Hyvärinen; John D Brannan; Hak-Kim Chan; Sandra D Anderson
Responsiveness to three bronchial provocation tests in patients with asthma.
Chest 2003;124(6):2171-7.
2003: Heikki O Koskela; Liisa Hyvärinen; John D Brannan; Hak-Kim Chan; Sandra D Anderson
Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma.
Chest 2003;124(4):1341-9.
2003: Hak-Kim Chan; Nora Y K Chew
Novel alternative methods for the delivery of drugs for the treatment of asthma.
Advanced drug delivery reviews 2003;55(7):793-805.
2003: Heikki O Koskela; Antti Taivainen; Hannu Tukiainen; Hak-Kim Chan
Inhalation challenge with bovine dander allergens: who needs it?
Chest 2003;124(1):383-91.
2003: Abolghasem Jouyban; F Jabbaribar; Hak-Kim Chan
An improved empirical model to calculate solute solubility in supercritical carbon dioxide.
Die Pharmazie 2003;58(6):396-8.
2003: Abolghasem Jouyban; Hak-Kim Chan; Maryam Khoubnasabjafari; BJ Clark
Calculation of electrophoretic mobility in ternary solvent electrolyte systems.
Journal of pharmaceutical and biomedical analysis 2003;32(2):203-8.
2003: Abolghasem Jouyban; Hak-Kim Chan; Brian John Clark; Ernst Kenndler
Comparison of different algorithms to calculate electrophoretic mobility of analytes as a function of binary solvent composition.
Electrophoresis 2003;24(10):1596-602.
2003: Karen Holzer; Sandra D Anderson; Hak-Kim Chan; Jo A Douglass
Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes.
American journal of respiratory and critical care medicine 2003;167(4):534-7.
2002: Evangelia Daviskas; Sandra D Anderson; Stefan Eberl; Hak-Kim Chan; Iven H Young; J Paul Seale
Effects of terbutaline in combination with mannitol on mucociliary clearance.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(6):1423-9.
2002: Abolghasem Jouyban; Hak-Kim Chan; Brian J Clark; William E Acree
Mathematical representation of apparent dissociation constants in aqueous-organic solvent mixtures.
International journal of pharmaceutics 2002;246(1-2):135-42.
2002: Abolghasem Jouyban; Hak-Kim Chan; Mohammad Barzegar-Jalali; William E Acree
A model to represent solvent effects on the chemical stability of solutes in mixed solvent systems.
International journal of pharmaceutics 2002;243(1-2):167-72.
2002: Nora Y K Chew; Hak-Kim Chan
Effect of powder polydispersity on aerosol generation.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2002;5(2):162-8.
2002: Abolghasem Jouyban; Susana Romero; Hak-Kim Chan; Brian John Clark; Pilar Bustamante
A cosolvency model to predict solubility of drugs at several temperatures from a limited number of solubility measurements.
Chemical & pharmaceutical bulletin 2002;50(5):594-9.
2002: Abolghasem Jouyban; Mahboob Rehman; Boris Y Shekunov; Hak-Kim Chan; Brian J Clark; Peter York
Solubility prediction in supercritical CO(2) using minimum number of experiments.
Journal of pharmaceutical sciences 2002;91(5):1287-95.
2002: Yuen-Han Lam; Rana T Bustami; Tung Phan; Hak-Kim Chan; Frances Separovic
A solid-state NMR study of protein mobility in lyophilized protein-sugar powders.
Journal of pharmaceutical sciences 2002;91(4):943-51.
2002: John D Brannan; Heikki O Koskela; Sandra D Anderson; Hak-Kim Chan
Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects.
Respirology (Carlton, Vic.) 2002;7(1):37-44.
2002: Nora Y K Chew; Hak-Kim Chan
The role of particle properties in pharmaceutical powder inhalation formulations.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(3):325-30.
2002: Sandra D Anderson; John D Brannan; Hak-Kim Chan
Use of aerosols for bronchial provocation testing in the laboratory: where we have been and where we are going.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(3):313-24.
2002: Hak-Kim Chan; Stefan Eberl; Evangelia Daviskas; Chris J Constable; Iven Young
Changes in lung deposition of aerosols due to hygroscopic growth: a fast SPECT study.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2002;15(3):307-11.
2002: Abolghasem Jouyban; Maryam Khoubnasabjafari; Hak-Kim Chan; Brian J Clark; William E Acree
Solubility prediction of anthracene in mixed solvents using a minimum number of experimental data.
Chemical & pharmaceutical bulletin 2002;50(1):21-5.
2001: Nora Y K Chew; Hak-Kim Chan
Use of solid corrugated particles to enhance powder aerosol performance.
Pharmaceutical research 2001;18(11):1570-7.
2001: Jörg D Leuppi; Cheryl Margaret Salome; Christine R Jenkins; Heikki O Koskela; John D Brannan; Sandra D Anderson; M Andersson; Hak-Kim Chan; Ann J Woolcock
Markers of airway inflammation and airway hyperresponsiveness in patients with well-controlled asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(3):444-50.
2001: Stefan Eberl; Hak-Kim Chan; Evangelia Daviskas; Chris J Constable; Iven Young
Aerosol deposition and clearance measurement: a novel technique using dynamic SPET.
European journal of nuclear medicine 2001;28(9):1365-72.
2001: A Jouyban-Gharamaleki; Siavoush Dastmalchi; Hak-Kim Chan; Jalal Hanaee; A Javanmard; Mohammad Barzegar-Jalali
Solubility prediction for furosemide in water-cosolvent mixtures using the minimum number of experiments.
Drug development and industrial pharmacy 2001;27(6):577-83.
2001: John D Brannan; Sandra D Anderson; K Gomes; Gregory G King; Hak-Kim Chan; J Paul Seale
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
American journal of respiratory and critical care medicine 2001;163(6):1420-5.
2001: Jörg D Leuppi; Cheryl Margaret Salome; Christine R Jenkins; Sandra D Anderson; Wei Xuan; Guy B Marks; Heikki O Koskela; John D Brannan; R Freed; M Andersson; Hak-Kim Chan; Ann J Woolcock
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids.
American journal of respiratory and critical care medicine 2001;163(2):406-12.
2001: Evangelia Daviskas; Sandra D Anderson; Stefan Eberl; Hak-Kim Chan; Iven H Young
The 24-h effect of mannitol on the clearance of mucus in patients with bronchiectasis.
Chest 2001;119(2):414-21.
2001: Nora Y K Chew; Hak-Kim Chan
In vitro aerosol performance and dose uniformity between the Foradile Aerolizer and the Oxis Turbuhaler.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2001;14(4):495-501.
2000: Rana T Bustami; Hak-Kim Chan; Fariba Dehghani; Neil R Foster
Generation of micro-particles of proteins for aerosol delivery using high pressure modified carbon dioxide.
Pharmaceutical research 2000;17(11):1360-6.
2000: Heikki O Koskela; M B Di Sciascio; Sandra D Anderson; M Andersson; Hak-Kim Chan; S Gadalla; C Katelaris
Nasal hyperosmolar challenge with a dry powder of mannitol in patients with allergic rhinitis. Evidence for epithelial cell involvement.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(11):1627-36.
2000: Nora Y K Chew; D F Bagster; Hak-Kim Chan
Effect of particle size, air flow and inhaler device on the aerosolisation of disodium cromoglycate powders.
International journal of pharmaceutics 2000;206(1-2):75-83.
2000: John D Brannan; Sandra D Anderson; R Freed; Jörg D Leuppi; Heikki O Koskela; Hak-Kim Chan
Nedocromil sodium inhibits responsiveness to inhaled mannitol in asthmatic subjects.
American journal of respiratory and critical care medicine 2000;161(6):2096-9.
2000: Nora Y K Chew; Hak-Kim Chan
The effect of spacers on the delivery of metered dose aerosols of nedocromil sodium and disodium cromoglycate.
International journal of pharmaceutics 2000;200(1):87-92.
1999: Michael Robinson; Evangelia Daviskas; Stefan Eberl; J Baker; Hak-Kim Chan; Sandra D Anderson; Peter T P Bye
The effect of inhaled mannitol on bronchial mucus clearance in cystic fibrosis patients: a pilot study.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):678-85.
1999: Nora Y K Chew; Hak-Kim Chan
Influence of particle size, air flow, and inhaler device on the dispersion of mannitol powders as aerosols.
Pharmaceutical research 1999;16(7):1098-103.
1999: Evangelia Daviskas; Sandra D Anderson; Stefan Eberl; Hak-Kim Chan; GJ Bautovich
Inhalation of dry powder mannitol improves clearance of mucus in patients with bronchiectasis.
American journal of respiratory and critical care medicine 1999;159(6):1843-8.
1999: Hak-Kim Chan; K L Au-Yeung; I Gonda
Development of a mathematical model for the water distribution in freeze-dried solids.
Pharmaceutical research 1999;16(5):660-5.
1999: Hak-Kim Chan; Evangelia Daviskas; Stefan Eberl; Michael Robinson; GJ Bautovich; Iven Young
Deposition of aqueous aerosol of technetium-99m diethylene triamine penta-acetic acid generated and delivered by a novel system (AERx) in healthy subjects.
European journal of nuclear medicine 1999;26(4):320-7.
1998: Frances Separovic; Yuen-Han Lam; X Ke; Hak-Kim Chan
A solid-state NMR study of protein hydration and stability.
Pharmaceutical research 1998;15(12):1816-21.
1998: Hak-Kim Chan; I Gonda
Solid state characterization of spray-dried powders of recombinant human deoxyribonuclease (rhDNase).
Journal of pharmaceutical sciences 1998;87(5):647-54.
1998: K J Smith; Hak-Kim Chan; KF Brown
Influence of flow rate on aerosol particle size distributions from pressurized and breath-actuated inhalers.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 1998;11(4):231-45.
1997: Evangelia Daviskas; Sandra D Anderson; John D Brannan; Hak-Kim Chan; Stefan Eberl; GJ Bautovich
Inhalation of dry-powder mannitol increases mucociliary clearance.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(11):2449-54.
1997: Hak-Kim Chan; A Clark; I Gonda; M Mumenthaler; C Hsu
Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery.
Pharmaceutical research 1997;14(4):431-7.
1996: Warren H Finlay; K W Stapleton; Hak-Kim Chan; Peter C Zuberbuhler; I Gonda
Regional deposition of inhaled hygroscopic aerosols: in vivo SPECT compared with mathematical modeling.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(1):374-83.
1996: Hak-Kim Chan; K L Au-Yeung; I Gonda
Effects of additives on heat denaturation of rhDNase in solutions.
Pharmaceutical research 1996;13(5):756-61.
1996: Hak-Kim Chan; B Ongpipattanakul; J Au-Yeung
Aggregation of rhDNase occurred during the compression of KBr pellets used for FTIR spectroscopy.
Pharmaceutical research 1996;13(2):238-42.
1995: Hak-Kim Chan; I Gonda
Physicochemical characterization of a new respirable form of nedocromil.
Journal of pharmaceutical sciences 1995;84(6):692-6.
1995: Evangelia Daviskas; Sandra D Anderson; I Gonda; Hak-Kim Chan; P Cook; R Fulton
Changes in mucociliary clearance during and after isocapnic hyperventilation in asthmatic and healthy subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(5):742-51.
1994: Hak-Kim Chan; P R Phipps; I Gonda; P Cook; R Fulton; I Young; G Bautovich
Regional deposition of nebulized hypodense nonisotonic solutions in the human respiratory tract.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(8):1483-9.
1994: JA Regnis; Michael Robinson; Dale Bailey; P Cook; P Hooper; Hak-Kim Chan; I Gonda; G Bautovich; Peter T P Bye
Mucociliary clearance in patients with cystic fibrosis and in normal subjects.
American journal of respiratory and critical care medicine 1994;150(1):66-71.
1989: Hak-Kim Chan; I Gonda
Respirable form of crystals of cromoglycic acid.
Journal of pharmaceutical sciences 1989;78(2):176-80.