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John Chan

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Lee Kozakiewicz; Jiayao Phuah; Joanne Flynn; John Chan
The Role of B Cells and Humoral Immunity in Mycobacterium tuberculosis Infection.
Venkataswamy Manjunatha; Andres Baena; John Chan; Michael F Goldberg; William R. Jacobs Jr.; Steven A Porcelli
In vitro culture medium influences the vaccine efficacy of Mycobacterium bovis BCG.
Kari A Sweeney; Manjunatha M Venkataswamy; Paras Jain; John Kim; Regy Lukose; Diane Ordway; Ian M Orme; Steven A Porcelli; Rani S Sellers; John Chan; Bing Chen; Mei Chen; Dee N Dao; Michael F Goldberg; Marcela Henao Tamayo; Tsungda Hsu; William R. Jacobs Jr.
A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis.

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All Publications

2013: Lee Kozakiewicz; Jiayao Phuah; Joanne Flynn; John Chan
The Role of B Cells and Humoral Immunity in Mycobacterium tuberculosis Infection.
Advances in experimental medicine and biology 2013;783():225-50.
2012: Venkataswamy Manjunatha; Andres Baena; John Chan; Michael F Goldberg; William R. Jacobs Jr.; Steven A Porcelli
In vitro culture medium influences the vaccine efficacy of Mycobacterium bovis BCG.
Vaccine 2012;30(6):1038-49.
2011: Kari A Sweeney; Manjunatha M Venkataswamy; Paras Jain; John Kim; Regy Lukose; Diane Ordway; Ian M Orme; Steven A Porcelli; Rani S Sellers; John Chan; Bing Chen; Mei Chen; Dee N Dao; Michael F Goldberg; Marcela Henao Tamayo; Tsungda Hsu; William R. Jacobs Jr.
A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis.
Nature medicine 2011;17(10):1261-8.
2011: J L Flynn; John Chan; P L Lin
Macrophages and control of granulomatous inflammation in tuberculosis.
Mucosal immunology 2011;4(3):271-8.
2009: Venkataswamy Manjunatha; Andres Baena; Michael F Goldberg; Gabriel Bricard; Jin S Im; John Chan; Faye Reddington; Gurdyal S Besra; William R. Jacobs Jr.; Steven A Porcelli
Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):1644-56.
2009: Joshua E Drumm; Kaixia Mi; Patrick Bilder; Meihao Sun; Jihyeon Lim; Helle Bielefeldt-Ohmann; Randall Basaraba; Melvin So; Guofeng Zhu; JoAnn M Tufariello; Angelo A Izzo; Ian M Orme; Steven C Almo; Thomas S Leyh; John Chan
Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection.
PLoS pathogens 2009;5(5):e1000460.
2009: Paul J Maglione; John Chan
How B cells shape the immune response against Mycobacterium tuberculosis.
European journal of immunology 2009;39(3):676-86.
2009: Anup Kesavan; Megan Brooks; JoAnn Tufariello; John Chan; Yukari C Manabe
Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model.
Tuberculosis (Edinburgh, Scotland) 2009;89(1):17-21.
2008: Lars Ny; Hua Li; Shankar Mukherjee; Katarina Persson; Bo Holmqvist; Dazhi Zhao; Vitaliy Shtutin; Huan Huang; Louis M Weiss; Fabiana S Machado; Stephen M Factor; John Chan; Herbert B Tanowitz; Linda Jelicks
A magnetic resonance imaging study of intestinal dilation in Trypanosoma cruzi-infected mice deficient in nitric oxide synthase.
The American journal of tropical medicine and hygiene 2008;79(5):760-7.
2008: Vanaja Kumar; Prabakaran Loganathan; Gomathi Sivaramakrishnan; Jordan Kriakov; Azger Dusthakeer; Balaji Subramanyam; John Chan; William R. Jacobs Jr.; Narayanan Paranji Rama
Characterization of temperate phage Che12 and construction of a new tool for diagnosis of tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2008;88(6):616-23.
2008: Eleanor Russell-Goldman; Jiayong Xu; Xiaobing Wang; John Chan; JoAnn M Tufariello
A Mycobacterium tuberculosis Rpf double-knockout strain exhibits profound defects in reactivation from chronic tuberculosis and innate immunity phenotypes.
Infection and immunity 2008;76(9):4269-81.
2008: Dee N Dao; Kari Sweeney; Tsungda Hsu; Sudagar S Gurcha; Ivan P Nascimento; Dan Roshevsky; Gurdyal S Besra; John Chan; Steven A Porcelli; William R. Jacobs Jr.
Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production.
PLoS pathogens 2008;4(6):e1000081.
2008: J Christian J Ray; Jian Wang; John Chan; Denise E Kirschner
The timing of TNF and IFN-gamma signaling affects macrophage activation strategies during Mycobacterium tuberculosis infection.
Journal of theoretical biology 2008;252(1):24-38.
2008: Yukari C Manabe; Anup Kesavan; Javier Lopez-Molina; Christine L Hatem; Megan Brooks; Ricardo Fujiwara; Karl Hochstein; M Louise M Pitt; Joann Tufariello; John Chan; David N McMurray; William R Bishai; Arthur M Dannenberg; Susana Mendez
The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome.
Tuberculosis (Edinburgh, Scotland) 2008;88(3):187-96.
2008: Azger Dusthackeer; Vanaja Kumar; Selvakumar Subbian; Gomathi Sivaramakrishnan; Guofang Zhu; Balaji Subramanyam; Sameer Hassan; Selvakumar Nagamaiah; John Chan; Narayanan Paranji Rama
Construction and evaluation of luciferase reporter phages for the detection of active and non-replicating tubercle bacilli.
Journal of microbiological methods 2008;73(1):18-25.
2008: Paul J Maglione; Jiayong Xu; Arturo Casadevall; John Chan
Fc gamma receptors regulate immune activation and susceptibility during Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3329-38.
2008: Soumya D Chakravarty; Guofeng Zhu; Ming C Tsai; Vellore P Mohan; Simeone Marino; Denise E Kirschner; Luqi Huang; Joanne Flynn; John Chan
Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs.
Infection and immunity 2008;76(3):916-26.
2007: Simeone Marino; Dhruv Sud; Hillarie Plessner; Philana Ling Lin; John Chan; JoAnne L Flynn; Denise E Kirschner
Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue.
PLoS computational biology 2007;3(10):1909-24.
2007: Joseph Hinchey; Sunhee C Lee; Bo Y Jeon; Randall J Basaraba; Venkataswamy Manjunatha; Bing Chen; John Chan; Miriam Braunstein; Ian M Orme; Steven C Derrick; Sheldon L Morris; William R. Jacobs Jr.; Steven A Porcelli
Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.
The Journal of clinical investigation 2007;117(8):2279-88.
2007: Paul J Maglione; Jiayong Xu; John Chan
B cells moderate inflammatory progression and enhance bacterial containment upon pulmonary challenge with Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7222-34.
2007: Hillarie L Plessner; Philana Ling Lin; Tadahiko Kohno; James S Louie; Denise E Kirschner; John Chan; JoAnne L Flynn
Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis.
The Journal of infectious diseases 2007;195(11):1643-50.
2007: Apoorva Bhatt; Nagatoshi Fujiwara; Kiranmai Bhatt; Sudagar S Gurcha; Laurent Kremer; Bing Chen; John Chan; Steven A Porcelli; Kazuo Kobayashi; Gurdyal S Besra; William R. Jacobs Jr.
Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5157-62.
2007: Soumya D Chakravarty; Jiayong Xu; Bao Lu; Craig Gerard; Joanne Flynn; John Chan
The chemokine receptor CXCR3 attenuates the control of chronic Mycobacterium tuberculosis infection in BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1723-35.
2006: Vasan K Sambandamurthy; Steven C Derrick; Tsungda Hsu; Bing Chen; Michelle H. Larsen; Kripa V Jalapathy; Mei Chen; John Kim; Steven A Porcelli; John Chan; Sheldon L Morris; William R. Jacobs Jr.
Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.
Vaccine 2006;24(37-39):6309-20.
2006: JoAnn M Tufariello; Kaixia Mi; Jiayong Xu; Yukari C Manabe; Anup Kesavan; Joshua Drumm; Kathryn Tanaka; William R. Jacobs Jr.; John Chan
Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis.
Infection and immunity 2006;74(5):2985-95.
2006: Eleanor Roy; A Dharshan De Silva; Vasan K Sambandamurthy; Simon O Clark; Evangelos Stavropoulos; William R. Jacobs Jr.; John Brennan; John Chan; Ann Williams; M Joseph Colston; Ricardo E Tascon
Induction of high levels of protective immunity in mice after vaccination using dendritic cells infected with auxotrophic mutants of Mycobacterium tuberculosis.
Immunology letters 2006;103(2):196-9.
2006: Ryan Senaratne; A Dharshan De Silva; Spencer J Williams; Joseph D Mougous; J Rachel Reader; Tianjiao Zhang; Stephen Chan; Ben Sidders; Dong H Lee; John Chan; Carolyn R Bertozzi; Lee W Riley
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.
Molecular microbiology 2006;59(6):1744-53.
2006: Ming C Tsai; Soumya Chakravarty; Guofeng Zhu; Jiayong Xu; Kathryn Tanaka; Cameron Koch; Joann Tufariello; Joanne Flynn; John Chan
Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension.
Cellular microbiology 2006;8(2):218-32.
2005: Eugenie Dubnau; John Chan; V P Mohan; Issar Smith
responses of mycobacterium tuberculosis to growth in the mouse lung.
Infection and immunity 2005;73(6):3754-7.
2005: JoAnne L Flynn; John Chan
What's good for the host is good for the bug.
Trends in microbiology 2005;13(3):98-102.
2004: Holly M Scott Algood; Philana Ling Lin; David Yankura; Alvin Jones; John Chan; JoAnne L Flynn
TNF influences chemokine expression of macrophages in vitro and that of CD11b+ cells in vivo during Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6846-57.
2004: John Chan; JoAnne Flynn
The immunological aspects of latency in tuberculosis.
Clinical immunology (Orlando, Fla.) 2004;110(1):2-12.
2004: JoAnn M Tufariello; William R. Jacobs Jr.; John Chan
Individual Mycobacterium tuberculosis resuscitation-promoting factor homologues are dispensable for growth in vitro and in vivo.
Infection and immunity 2004;72(1):515-26.
2003: Holly M Scott Algood; John Chan; JoAnne L Flynn
Chemokines and tuberculosis.
Cytokine & growth factor reviews 2003;14(6):467-77.
2003: JoAnn M Tufariello; John Chan; JoAnne L Flynn
Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection.
The Lancet infectious diseases 2003;3(9):578-90.
2003: Hideaki Ohno; Guofeng Zhu; Vellore P Mohan; Darien Chu; Shigeru Kohno; William R. Jacobs Jr.; John Chan
The effects of reactive nitrogen intermediates on gene expression in Mycobacterium tuberculosis.
Cellular microbiology 2003;5(9):637-48.
2003: JoAnne L Flynn; John Chan
Immune evasion by Mycobacterium tuberculosis: living with the enemy.
Current opinion in immunology 2003;15(4):450-5.
2003: Guofeng Zhu; Huifang Xiao; Vellore P Mohan; Kathryn Tanaka; Sanjay Tyagi; Fred Tsen; Padmini Salgame; John Chan
Gene expression in the tuberculous granuloma: analysis by laser capture microdissection and real-time PCR.
Cellular microbiology 2003;5(7):445-53.
2003: Huan Huang; Stefka B Petkova; Alex W Cohen; Boumediene Bouzahzah; John Chan; Jian-nian Zhou; Stephen M Factor; Louis M Weiss; Mohan Krishnamachary; Shankar Mukherjee; Murray Wittner; Richard N Kitsis; Richard G Pestell; Michael P Lisanti; Chris Albanese; Herbert B Tanowitz
Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Infection and immunity 2003;71(5):2859-67.
2003: Miriam Braunstein; Benjamin J Espinosa; John Chan; John Belisle; William R. Jacobs Jr.
SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis.
Molecular microbiology 2003;48(2):453-64.
2003: Svetoslav Bardarov; Horng Dou; Katherine Eisenach; Niaz Banaiee; S u Ya; John Chan; William R. Jacobs Jr.; Paul F Riska
Detection and drug-susceptibility testing of M. tuberculosis from sputum samples using luciferase reporter phage: comparison with the Mycobacteria Growth Indicator Tube (MGIT) system.
Diagnostic microbiology and infectious disease 2003;45(1):53-61.
2002: Svetoslav Bardarov; Svetoslav Bardarov Jr; Martin S Pavelka Jr; Vasan Sambandamurthy; Michelle H. Larsen; JoAnn Tufariello; John Chan; Graham F Hatfull; William R Jacobs Jr
Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.
Microbiology (Reading, England) 2002;148(Pt 10):3007-17.
2002: Madhulika Chandra; Herbert B Tanowitz; Stefka B Petkova; Huan Huang; Louis M Weiss; Murray Wittner; Stephen M Factor; Vitaliy Shtutin; Linda Jelicks; John Chan; Jamshid Shirani
Significance of inducible nitric oxide synthase in acute myocarditis caused by Trypanosoma cruzi (Tulahuen strain).
International journal for parasitology 2002;32(7):897-905.
2002: Herbert B Tanowitz; Louis M Weiss; John Chan
Neutrophil migration and sepsis.
Critical care medicine 2002;30(5):1169-70.
2002: Somia Perdow Hickman; John Chan; Padmini Salgame
Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4636-42.
2001: Charles A Scanga; VP Mohan; Kathryn Tanaka; DAvid Alland; JoAnne L Flynn; John Chan
The inducible nitric oxide synthase locus confers protection against aerogenic challenge of both clinical and laboratory strains of Mycobacterium tuberculosis in mice.
Infection and immunity 2001;69(12):7711-7.
2001: Edward D Chan; John Chan; N W Schluger
What is the role of nitric oxide in murine and human host defense against tuberculosis?Current knowledge.
American journal of respiratory cell and molecular biology 2001;25(5):606-12.
2001: JoAnne L Flynn; John Chan
Tuberculosis: latency and reactivation.
Infection and immunity 2001;69(7):4195-201.
2001: VP Mohan; Charles A Scanga; K Yu; Holly M Scott; Kathryn Tanaka; E Tsang; M M Tsai; JoAnne L Flynn; John Chan
Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology.
Infection and immunity 2001;69(3):1847-55.
2001: J L Flynn; John Chan
Immunology of tuberculosis.
Annual review of immunology 2001;19():93-129.
2000: Huan Huang; Stefka B Petkova; Richard G Pestell; Boumediene Bouzahzah; John Chan; H Magazine; Louis M Weiss; George Christ; Michael P Lisanti; Stephen Douglas; Vitaliy Shtutin; Sandra K Halonen; Murray Wittner; Herbert B Tanowitz
Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S148-50.
2000: Stefka B Petkova; Herbert B Tanowitz; H I Magazine; Stephen M Factor; John Chan; Richard G Pestell; Boumediene Bouzahzah; Stephen Douglas; Vitaliy Shtutin; Stephen A Morris; E Tsang; Louis M Weiss; George Christ; Murray Wittner; Huan Huang
Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2000;9(5):257-65.
2000: C Hu; T Mayadas-Norton; Kathryn Tanaka; John Chan; Padmini Salgame
Mycobacterium tuberculosis infection in complement receptor 3-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2596-602.
2000: Charles A Scanga; VP Mohan; K Yu; H Joseph; Kathryn Tanaka; John Chan; JoAnne L Flynn
Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2.
The Journal of experimental medicine 2000;192(3):347-58.
2000: Herbert B Tanowitz; John Chan
Gram-positive sepsis.
Critical care medicine 2000;28(8):3081-2.
2000: Eugenie Dubnau; John Chan; Catherine Raynaud; V P Mohan; Marie-Antoinette Lanéelle; K Yu; Annaïk Quémard; Issar Smith; Mamadou Daffé
Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice.
Molecular microbiology 2000;36(3):630-7.
2000: Y Tian; Y Xing; Richard Magliozzo; K Yu; B R Bloom; John Chan
A commercial preparation of catalase inhibits nitric oxide production by activated murine macrophages: role of arginase.
Infection and immunity 2000;68(5):3015-8.
2000: Mary K Hondalus; Svetoslav Bardarov; R Russell; John Chan; William R. Jacobs Jr.; Barry R Bloom
Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis.
Infection and immunity 2000;68(5):2888-98.
2000: J Browning Paul; Emilie-Jeanne Wang; Massimo Pettoello-Mantovani; CA Raker; SV Yurasov; M M Goldstein; James W Horner; John Chan; Harris Goldstein
Mice transgenic for monocyte-tropic HIV type 1 produce infectious virus and display plasma viremia: a new in vivo system for studying the postintegration phase of HIV replication.
AIDS research and human retroviruses 2000;16(5):481-92.
1999: L Ny; Katarina Persson; Bengt Larsson; John Chan; Louis M Weiss; M Wittner; Huan Huang; Herbert B Tanowitz
Localization and activity of nitric oxide synthases in the gastrointestinal tract of Trypanosoma cruzi-infected mice.
Journal of neuroimmunology 1999;99(1):27-35.
1999: Charles A Scanga; VP Mohan; H Joseph; K Yu; John Chan; JoAnne L Flynn
Reactivation of latent tuberculosis: variations on the Cornell murine model.
Infection and immunity 1999;67(9):4531-8.
1999: Linda Jelicks; Jamshid Shirani; Murray Wittner; Madhulika Chandra; Louis M Weiss; Stephen M Factor; I Bekirov; Vicki L Braunstein; John Chan; Huan Huang; Herbert B Tanowitz
Application of cardiac gated magnetic resonance imaging in murine Chagas' disease.
The American journal of tropical medicine and hygiene 1999;61(2):207-14.
1999: Paul F Riska; Ya Su; Svetoslav Bardarov; L Freundlich; G Sarkis; Graham F Hatfull; C Carrière; V Kumar; John Chan; William R. Jacobs Jr.
Rapid film-based determination of antibiotic susceptibilities of Mycobacterium tuberculosis strains by using a luciferase reporter phage and the Bronx Box.
Journal of clinical microbiology 1999;37(4):1144-9.
1999: K Yu; C Mitchell; Y Xing; Richard Magliozzo; B R Bloom; John Chan
Toxicity of nitrogen oxides and related oxidants on mycobacteria: M. tuberculosis is resistant to peroxynitrite anion.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;79(4):191-8.
1999: Huan Huang; John Chan; Murray Wittner; Linda Jelicks; Stephen A Morris; Stephen M Factor; Louis M Weiss; Vicki L Braunstein; Cyrus J Bacchi; Nigel Yarlett; Madhulika Chandra; Jamshid Shirani; Herbert B Tanowitz
Expression of cardiac cytokines and inducible form of nitric oxide synthase (NOS2) in Trypanosoma cruzi-infected mice.
Journal of molecular and cellular cardiology 1999;31(1):75-88.
1998: JoAnne L Flynn; Charles A Scanga; Kathryn Tanaka; John Chan
Effects of aminoguanidine on latent murine tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1796-803.
1997: C Carrière; Paul F Riska; O Zimhony; Jordan Kriakov; Svetoslav Bardarov; Judah Burns; John Chan; William R. Jacobs Jr.
Conditionally replicating luciferase reporter phages: improved sensitivity for rapid detection and assessment of drug susceptibility of Mycobacterium tuberculosis.
Journal of clinical microbiology 1997;35(12):3232-9.
1997: Paul F Riska; William R. Jacobs Jr.; Barry R Bloom; John McKitrick; John Chan
Specific identification of Mycobacterium tuberculosis with the luciferase reporter mycobacteriophage: use of p-nitro-alpha-acetylamino-beta-hydroxy propiophenone.
Journal of clinical microbiology 1997;35(12):3225-31.
1996: John Chan; Y Tian; Kathryn Tanaka; M S Tsang; K Yu; P Salgame; D Carroll; Yvonne Kress; R Teitelbaum; Barry R Bloom
Effects of protein calorie malnutrition on tuberculosis in mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14857-61.
1995: JoAnne L Flynn; M M Goldstein; John Chan; K J Triebold; K Pfeffer; Charles J Lowenstein; R Schreiber; T W Mak; Barry R Bloom
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice.
Immunity 1995;2(6):561-72.
1995: John Chan; Kathryn Tanaka; D Carroll; J Flynn; B R Bloom
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.
Infection and immunity 1995;63(2):736-40.
1994: Barry R Bloom; J Flynn; K McDonough; Y Kress; John Chan
Experimental approaches to mechanisms of protection and pathogenesis in M. tuberculosis infection.
Immunobiology 1994;191(4-5):526-36.
1993: JoAnne L Flynn; John Chan; K J Triebold; Dyana Dalton; Timothy A Stewart; Barry R Bloom
An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.
The Journal of experimental medicine 1993;178(6):2249-54.
1993: William R. Jacobs Jr.; R G Barletta; R Udani; John Chan; Gary Kalkut; Gabriel Sosne; T Kieser; G J Sarkis; Graham F Hatfull; Barry R Bloom
Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages.
Science (New York, N.Y.) 1993;260(5109):819-22.
1992: John Chan; Y Xing; Richard Magliozzo; Barry R Bloom
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.
The Journal of experimental medicine 1992;175(4):1111-22.
1991: John Chan; X D Fan; S W Hunter; Patrick J Brennan; Barry R Bloom
Lipoarabinomannan, a possible virulence factor involved in persistence of Mycobacterium tuberculosis within macrophages.
Infection and immunity 1991;59(5):1755-61.
1989: C L Cooper; Christoph Mueller; T A Sinchaisri; C Pirmez; John Chan; G Kaplan; S M Young; I L Weissman; Barry R Bloom; Thomas H Rea
Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization.
The Journal of experimental medicine 1989;169(5):1565-81.
1989: John Chan; T Fujiwara; P Brennan; M McNeil; S J Turco; J C Sibille; M Snapper; Philip Aisen; B R Bloom
Microbial glycolipids: possible virulence factors that scavenge oxygen radicals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2453-7.
1984: John Chan; John McKitrick; R S Klein
Mycobacterium gordonae in the acquired immunodeficiency syndrome.
Annals of internal medicine 1984;101(3):400.