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Sean Alber

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Anamika Bose; Peter A Cohen; James H Finke; Jorge A Garcia; Jennifer S Ko; Brian I Rini; Jennifer L Taylor; Simon C Watkins; Sean Alber; Walter J Storkus
Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination.
Xi Zhao; Anamika Bose; Hideo Komita; Jennifer L Taylor; Mayumi Kawabe; Nina Chi; Laima Spokas; Devin B Lowe; Christina Goldbach; Sean Alber; Simon C Watkins; Lisa H Butterfield; Pawel Kalinski; John M Kirkwood; Walter J Storkus
Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens.
Guojun Chen; Xiaoyan Yang; Sean Alber; Vladimir Shusterman; Guy Salama
Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen.

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All Publications

2011: Anamika Bose; Peter A Cohen; James H Finke; Jorge A Garcia; Jennifer S Ko; Brian I Rini; Jennifer L Taylor; Simon C Watkins; Sean Alber; Walter J Storkus
Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination.
International journal of cancer. Journal international du cancer 2011;129(9):2158-70.
2011: Xi Zhao; Anamika Bose; Hideo Komita; Jennifer L Taylor; Mayumi Kawabe; Nina Chi; Laima Spokas; Devin B Lowe; Christina Goldbach; Sean Alber; Simon C Watkins; Lisa H Butterfield; Pawel Kalinski; John M Kirkwood; Walter J Storkus
Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):805-14.
2011: Guojun Chen; Xiaoyan Yang; Sean Alber; Vladimir Shusterman; Guy Salama
Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen.
The Journal of physiology 2011;589(Pt 5):1061-80.
2010: Nam Vo; Hyoung Yeon Seo; Andria Robinson; Gwendolyn Sowa; Douglas Bentley; Lauren Taylor; Rebecca K Studer; Arvydas Usas; Johnny Huard; Sean Alber; simon simon watkins; Joon Lee; Paulo Coehlo; Dong Wang; Mattia Loppini; Paul D Robbins; Laura J Niedernhofer; James Kang
Accelerated aging of intervertebral discs in a mouse model of progeria.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010;28(12):1600-7.
2010: Angela D Pardee; Dustin McCurry; Sean Alber; Peisheng Hu; Alan L Epstein; Walter J Storkus
A therapeutic OX40 agonist dynamically alters dendritic, endothelial, and T cell subsets within the established tumor microenvironment.
Cancer research 2010;70(22):9041-52.
2010: Chang-Sook Hong; Wendy Fellows; Ajay Niranjan; Sean Alber; simon simon watkins; Justus B Cohen; Joseph C Glorioso; P Grandi
Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection.
Gene therapy 2010;17(10):1200-5.
2010: Lazar Vujanovic; David E Szymkowski; Sean Alber; simon simon watkins; Nikola L Vujanovic; Lisa H Butterfield
Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.
Blood 2010;116(4):575-83.
2009: Liang Zheng; Zhihong Zhou; Ling Lin; Sean Alber; simon simon watkins; Naftali Kaminski; Augustine M K Choi; Danielle Morse
Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosis.
American journal of respiratory cell and molecular biology 2009;41(1):85-92.
2009: Narasimhan J Venkatachari; Sean Alber; simon simon watkins; Velpandi Ayyavoo
HIV-1 infection of DC: evidence for the acquisition of virus particles from infected T cells by antigen uptake mechanism.
PloS one 2009;4(10):e7470.
2008: Hideo Komita; Xi Zhao; Jennifer L Taylor; Louis J Sparvero; Andrew A Amoscato; Sean Alber; simon simon watkins; Angela D Pardee; Amy Wesa; Walter J Storkus
CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growth.
Cancer research 2008;68(19):8076-84.
2008: Ling Lin; Zhihong Zhou; Liang Zheng; Sean Alber; simon simon watkins; Prabir Ray; Naftali Kaminski; Yingze Zhang; Danielle Morse
Cross talk between Id1 and its interactive protein Dril1 mediate fibroblast responses to transforming growth factor-beta in pulmonary fibrosis.
The American journal of pathology 2008;173(2):337-46.
2008: Alexander Hoetzel; Tamás Dolinay; Simone Vallbracht; Yingze Zhang; hong pyo kim; Emeka Ifedigbo; Sean Alber; A Murat Kaynar; Rene Schmidt; Stefan W Ryter; Augustine M K Choi
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.
American journal of respiratory and critical care medicine 2008;177(11):1223-32.
2007: Robert S B Clark; Paula D Nathaniel; Xiaopeng Zhang; C Edward Dixon; Sean Alber; simon simon watkins; John A Melick; Patrick M Kochanek; Steven H Graham
boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(2):316-26.
2006: Xiaopeng Zhang; Sean Alber; simon simon watkins; Patrick M Kochanek; Donald W Marion; Steven H Graham; Robert S B Clark
Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans.
Journal of neurotrauma 2006;23(11):1583-90.
2006: Angela Y Song; Morad Askari; Erdrin Azemi; Sean Alber; Dennis J Hurwitz; Kacey Marra; Kenneth C Shestak; Richard Debski; J Peter Rubin
Biomechanical properties of the superficial fascial system.
Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 2006;26(4):395-403.
2006: Aklile Berhanu; Jian Huang; Sean Alber; simon simon watkins; Walter J Storkus
Combinational FLt3 ligand and granulocyte macrophage colony-stimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8(+) T-cell cross-priming but is ineffective as a therapy.
Cancer research 2006;66(9):4895-903.
2006: Fengtian He; Jiang Li; Ying Mu; Ramalinga Kuruba; Zheng Ma; Annette Wilson; Sean Alber; Yu Jiang; Troy Stevens; simon simon watkins; Bruce R Pitt; Wen Xie; Song Li
Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells.
Circulation research 2006;98(2):192-9.
2005: Robbie B Mailliard; Sean Alber; Hongmei Shen; simon simon watkins; John M Kirkwood; Ronald Herberman; Pawel Kalinski
IL-18-induced CD83+CCR7+ NK helper cells.
The Journal of experimental medicine 2005;202(7):941-53.
2005: Annette Wilson; Wen Zhou; Hunter C Champion; Sean Alber; Zi-Lue Tang; Steven Kennel; simon simon watkins; Leaf Huang; Bruce R Pitt; Song Li
Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):510-8.
2005: Olga Azhipa; Kei Kimizuka; Atsunori Nakao; Hideyoshi Toyokawa; Toyokazu Okuda; Joao Seda Neto; Sean Alber; Takashi Kaizu; Angus W Thomson; Anthony J Demetris; Noriko Murase
Comparative analysis of the fate of donor dendritic cells and B cells and their influence on alloreactive T cell responses under tacrolimus immunosuppression.
Clinical immunology (Orlando, Fla.) 2005;114(2):199-209.
2005: Zhihong Zhou; Ruiping Song; Cheryl L Fattman; Sara Greenhill; Sean Alber; Tim D Oury; Augustine M K Choi; Danielle Morse
Carbon monoxide suppresses bleomycin-induced lung fibrosis.
The American journal of pathology 2005;166(1):27-37.
2004: Eva Pizzoferrato; Ye Liu; Andrea Gambotto; Michaele J Armstrong; Michael T Stang; William Gooding; Sean Alber; Stuart H Shand; simon simon watkins; Walter J Storkus; John H Yim
Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin.
Cancer research 2004;64(22):8381-8.
2004: Tracy Cook; Zifa Wang; Sean Alber; Kaihong Liu; simon simon watkins; Yoram Vodovotz; Timothy R Billiar; David Blumberg
Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53.
Cancer research 2004;64(21):8015-21.
2004: Wen Ning; Chao-Jun Li; Naftali Kaminski; Carol A Feghali-Bostwick; Sean Alber; Yuanpu P Di; Sherrie L Otterbein; Ruiping Song; Shizu Hayashi; Zhihong Zhou; David J Pinsky; simon simon watkins; Joseph M Pilewski; Frank C Sciurba; David G Peters; James C Hogg; Augustine M K Choi
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(41):14895-900.
2004: Ravi Ramani; Michael A Mathier; Ping Wang; Gregory Gibson; Sandra Tögel; Jennifer Dawson; Anthony Bauer; Sean Alber; simon simon watkins; Charles F McTiernan; Arthur M Feldman
Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling.
American journal of physiology. Heart and circulatory physiology 2004;287(3):H1369-77.
2004: Runkuan Yang; Takashi Uchiyama; Sean Alber; Xiaonan Han; simon simon watkins; Russell L Delude; Mitchell Fink
Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis.
Critical care medicine 2004;32(7):1453-9.
2004: Zifa Wang; Tracy Cook; Sean Alber; Kaihong Liu; Imre Kovesdi; simon simon watkins; Yoram Vodovotz; Timothy R Billiar; David Blumberg
Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity.
Cancer research 2004;64(4):1386-95.
2004: Richard Steinman; Beatrice B Yaroslavskiy; Julie P Goff; Sean Alber; simon simon watkins
Cdk-inhibitors and exit from quiescence in primitive haematopoietic cell subsets.
British journal of haematology 2004;124(3):358-65.
2003: Kevin Brown; Wentao Gao; Sean Alber; Anita M Trichel; Michael Murphey-Corb; simon simon watkins; Andrea Gambotto; Simon M Barratt-Boyes
Adenovirus-transduced dendritic cells injected into skin or lymph node prime potent simian immunodeficiency virus-specific T cell immunity in monkeys.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6875-82.
2003: Tomohide Tatsumi; Jian Huang; William Gooding; Andrea Gambotto; Paul D Robbins; Nikola L Vujanovic; Sean Alber; simon simon watkins; Hideho Okada; Walter J Storkus
Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity.
Cancer research 2003;63(19):6378-86.
2003: Purnima Pathre; Kuntala Shome; Anna Blumental-Perry; Anna Bielli; Charles J Haney; Sean Alber; simon simon watkins; Guillermo Romero; Meir Aridor
Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export.
The EMBO journal 2003;22(16):4059-69.
2003: Ruiping Song; Masatoshi Kubo; Danielle Morse; Zhihong Zhou; Xuchen Zhang; James H Dauber; James P Fabisiak; Sean Alber; simon simon watkins; Brian Zuckerbraun; Leo E Otterbein; Wen Ning; Tim D Oury; Patty J Lee; Kenneth R McCurry; Augustine M K Choi
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects.
The American journal of pathology 2003;163(1):231-42.
2003: Danielle Morse; Leo E Otterbein; simon simon watkins; Sean Alber; Zhihong Zhou; Richard A Flavell; Roger J Davis; Augustine M K Choi
Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice.
American journal of physiology. Lung cellular and molecular physiology 2003;285(1):L250-7.
2003: Junlan Zhang; Annette Wilson; Sean Alber; Zheng Ma; Zi-Lue Tang; E Satoh; O Mazda; simon simon watkins; Leaf Huang; Bruce R Pitt; Song Li
Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein-Barr virus-based episomal plasmid.
Gene therapy 2003;10(9):822-6.
2003: Michael A Pezzone; simon simon watkins; Sean Alber; William E King; william chesney de groat; Michael B Chancellor; Matthew Fraser
Identification of c-kit-positive cells in the mouse ureter: the interstitial cells of Cajal of the urinary tract.
American journal of physiology. Renal physiology 2003;284(5):F925-9.
2003: Xing Yuan; Zheng Ma; Wen Zhou; Takuro Niidome; Sean Alber; Leaf Huang; simon simon watkins; Song Li
Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium.
Biochemical and biophysical research communications 2003;302(1):6-11.
2003: Richard E Redlinger; Takashi Shimizu; Thierry Remy; Sean Alber; simon simon watkins; Edward M Barksdale
Cellular mechanisms of interleukin-12-mediated neuroblastoma regression.
Journal of pediatric surgery 2003;38(2):199-204.
2003: Joy L Collins; Yoram Vodovotz; Christian Hierholzer; Raphael T Villavicencio; Shubing Liu; Sean Alber; David J Gallo; Donna B Stolz; simon simon watkins; Anthony Godfrey; William Gooding; Edward Kelly; Andrew B Peitzman; Timothy R Billiar
Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock.
Shock (Augusta, Ga.) 2003;19(2):117-22.
2002: Zheng Ma; Junlan Zhang; Sean Alber; John Dileo; Yoichi Negishi; Donna Stolz; simon simon watkins; Leaf Huang; Bruce R Pitt; Song Li
Lipid-mediated delivery of oligonucleotide to pulmonary endothelium.
American journal of respiratory cell and molecular biology 2002;27(2):151-9.
2002: Zheng Ma; Zhibao Mi; Annette Wilson; Sean Alber; Paul D Robbins; simon simon watkins; Bruce R Pitt; Song Li
Redirecting adenovirus to pulmonary endothelium by cationic liposomes.
Gene therapy 2002;9(3):176-82.
2001: Beatrice B Yaroslavskiy; simon simon watkins; Sean Alber; Richard A Steinman
Dynamic changes in p27kip1 variant expression in activated lymphocytes.
Journal of cellular biochemistry 2001;83(3):380-9.
2001: Evan P Nadler; Ala Stanford; Xiao-Ru Zhang; Laura C Schall; Sean Alber; simon simon watkins; Henri R Ford
Intestinal cytokine gene expression in infants with acute necrotizing enterocolitis: interleukin-11 mRNA expression inversely correlates with extent of disease.
Journal of pediatric surgery 2001;36(8):1122-9.
2001: Toru Kubota; M Miyagishima; Carole S Frye; Sean Alber; GS Bounoutas; Toshiaki Kadokami; simon simon watkins; Charles F McTiernan; Arthur M Feldman
Overexpression of tumor necrosis factor- alpha activates both anti- and pro-apoptotic pathways in the myocardium.
Journal of molecular and cellular cardiology 2001;33(7):1331-44.
2001: Evan P Nadler; EC Dickinson; Donna Beer-Stolz; Sean Alber; simon simon watkins; D W Pratt; Henri R Ford
Scavenging nitric oxide reduces hepatocellular injury after endotoxin challenge.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(1):G173-81.
2001: Beatrice B Yaroslavskiy; D B Stolz; simon simon watkins; Sean Alber; Neil A Bradbury; Richard A Steinman
p27Kip1 localizes to detergent-insoluble microdomains within lymphocyte membranes.
Molecular medicine (Cambridge, Mass.) 2001;7(1):49-58.
2000: C A Black; Lisa C Rohan; M Cost; simon simon watkins; Romesh A Draviam; Sean Alber; Robert P Edwards
Vaginal mucosa serves as an inductive site for tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5077-83.
2000: EC Dickinson; R Tuncer; Evan P Nadler; U Koltuksuz; Patricia Boyle; Sean Alber; simon simon watkins; Henri R Ford
Recombinant human interleukin-11 prevents mucosal atrophy and bowel shortening in the defunctionalized intestine.
Journal of pediatric surgery 2000;35(7):1079-83.
1999: EC Dickinson; R Tuncer; Evan P Nadler; Patricia Boyle; Sean Alber; S Watkins; H Ford
NOX, a novel nitric oxide scavenger, reduces bacterial translocation in rats after endotoxin challenge.
The American journal of physiology 1999;277(6 Pt 1):G1281-7.
1999: Maryam Feili-Hariri; Xin Dong; Sean Alber; simon simon watkins; Russell D Salter; Penelope A Morel
Immunotherapy of NOD mice with bone marrow-derived dendritic cells.
Diabetes 1999;48(12):2300-8.
1998: EC Dickinson; J C Gorga; M Garrett; R Tuncer; Patricia Boyle; simon simon watkins; Sean Alber; Maria Parizhskaya; Massimo Trucco; MI Rowe; Henri R Ford
Immunoglobulin A supplementation abrogates bacterial translocation and preserves the architecture of the intestinal epithelium.
Surgery 1998;124(2):284-90.
1998: Flordeliza S Villanueva; R J Jankowski; S Klibanov; M L Pina; Sean Alber; simon simon watkins; Gary H Brandenburger; William R Wagner
Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells.
Circulation 1998;98(1):1-5.
1998: R Benoit; S Rowe; simon simon watkins; Patricia Boyle; M Garrett; Sean Alber; J Wiener; MI Rowe; Henri R Ford
Pure endotoxin does not pass across the intestinal epithelium in vitro.
Shock (Augusta, Ga.) 1998;10(1):43-8.