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Ronald Chance

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

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High Pressure Liquid Chromatography

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Publications

TOP 3
Mark L Brader; Muppalla Sukumar; Allen H Pekar; David S McClellan; Ronald E Chance; David B Flora; Amy L Cox; Lynnie Irwin; Sharon R Myers
Hybrid insulin cocrystals for controlled release delivery.
Michael R Defelippis; Ronald E Chance; Bruce Frank
Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics.
Frederick G Hamel; Gerri L Siford; Janet Fawcett; Ronald E Chance; Bruce Frank; William C Duckworth
Differences in the cellular processing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin.

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All Publications

2002: Mark L Brader; Muppalla Sukumar; Allen H Pekar; David S McClellan; Ronald E Chance; David B Flora; Amy L Cox; Lynnie Irwin; Sharon R Myers
Hybrid insulin cocrystals for controlled release delivery.
Nature biotechnology 2002;20(8):800-4.
2001: Michael R Defelippis; Ronald E Chance; Bruce Frank
Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics.
Critical reviews in therapeutic drug carrier systems 2001;18(2):201-64.
1999: Frederick G Hamel; Gerri L Siford; Janet Fawcett; Ronald E Chance; Bruce Frank; William C Duckworth
Differences in the cellular processing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin.
Metabolism: clinical and experimental 1999;48(5):611-7.
1999: Ronald R Bowsher; R A Lynch; Patricia Brown-Augsburger; Paula Santa; W E Legan; J R Woodworth; Ronald E Chance
Sensitive RIA for the specific determination of insulin lispro.
Clinical chemistry 1999;45(1):104-10.
1998: J P Richards; MP Stickelmeyer; David B Flora; Ronald E Chance; Bruce Frank; Michael R Defelippis
Self-association properties of monomeric insulin analogs under formulation conditions.
Pharmaceutical research 1998;15(9):1434-41.
1997: Y Ido; Alessandro Vindigni; K Chang; L Stramm; Ronald E Chance; W F Heath; Richard D Dimarchi; Enrico Di Cera; J R Williamson
Prevention of vascular and neural dysfunction in diabetic rats by C-peptide.
Science (New York, N.Y.) 1997;277(5325):563-6.
1997: Lawrence J Slieker; G S Brooke; Richard D Dimarchi; David B Flora; L K Green; J A Hoffmann; H B Long; L Fan; J E Shields; K L Sundell; PL Surface; Ronald E Chance
Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.
Diabetologia 1997;40 Suppl 2():S54-61.
1997: Jerry Radziuk; J C Davies; W S Pye; J E Shields; Richard D Dimarchi; Ronald E Chance
Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs--LysB28ProB29-human insulin and AspB10LysB28ProB29-human insulin--assessed in a conscious pig model.
Diabetes 1997;46(4):548-56.
1996: Donald R Gehlert; Douglas A Schober; Lisa S Beavers; Robert A Gadski; J A Hoffman; D L Smiley; Ronald E Chance; Ingrid Lundell; Dan Larhammar
Characterization of the peptide binding requirements for the cloned human pancreatic polypeptide-preferring receptor.
Molecular pharmacology 1996;50(1):112-8.
1994: Richard D Dimarchi; Ronald E Chance; H B Long; J E Shields; Lawrence J Slieker
Preparation of an insulin with improved pharmacokinetics relative to human insulin through consideration of structural homology with insulin-like growth factor I.
Hormone research 1994;41 Suppl 2():93-6.
1993: Ronald E Chance; Bruce Frank
Research, development, production, and safety of biosynthetic human insulin.
Diabetes care 1993;16 Suppl 3():133-42.
1993: Gary G Berntson; WB Zipf; Thomas M O'Dorisio; J A Hoffman; Ronald E Chance
Pancreatic polypeptide infusions reduce food intake in Prader-Willi syndrome.
Peptides 1993;14(3):497-503.
1993: Lawrence J Slieker; G S Brooke; Ronald E Chance; L Fan; J A Hoffmann; D C Howey; H B Long; J Mayer; J E Shields; Karen Sundell
Insulin and IGF-I analogs: novel approaches to improved insulin pharmacokinetics.
Advances in experimental medicine and biology 1993;343():25-32.
1992: D N Brems; L A Alter; M J Beckage; Ronald E Chance; Richard D Dimarchi; L K Green; H B Long; A H Pekar; J E Shields; Bruce Frank
Altering the association properties of insulin by amino acid replacement.
Protein engineering 1992;5(6):527-33.
1992: D N Brems; P L Brown; C Bryant; Ronald E Chance; L K Green; H B Long; A A Miller; R Millican; J E Shields; Bruce Frank
Improved insulin stability through amino acid substitution.
Protein engineering 1992;5(6):519-25.
1992: C Bryant; M Strohl; L K Green; H B Long; L A Alter; A H Pekar; Ronald E Chance; D N Brems
Detection of an equilibrium intermediate in the folding of a monomeric insulin analog.
Biochemistry 1992;31(25):5692-8.
1992: W F Heath; R M Belagaje; G S Brooke; Ronald E Chance; J A Hoffmann; H B Long; S G Reams; C Roundtree; W N Shaw; Lawrence J Slieker
(A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin.
The Journal of biological chemistry 1992;267(1):419-25.
1990: J A Hoffmann; Ronald E Chance; M G Johnson
Purification and analysis of the major components of chum salmon protamine contained in insulin formulations using high-performance liquid chromatography.
Protein expression and purification 1990;1(2):127-33.
1984: Bruce Frank; A H Pekar; J M Pettee; E M Schirmer; M G Johnson; Ronald E Chance
Isolation and characterization of a genetic variant of bovine proinsulin.
International journal of peptide and protein research 1984;23(5):506-15.
1984: J R Kimmel; H G Pollock; Ronald E Chance; M G Johnson; J R Reeve; I L Taylor; C Miller; J E Shively
Pancreatic polypeptide from rat pancreas.
Endocrinology 1984;114(5):1725-31.
1983: J A Hoffman; Ronald E Chance
Crystallization of bovine pancreatic polypeptide.
Biochemical and biophysical research communications 1983;116(3):830-5.