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Chien-Hsing Chang

Research Profile

Chemicals & Drugs

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Tumor Cell Line

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TOP 3
Robert M Sharkey; Catharina M van Rij; Otto C Boerman; Thomas M Cardillo; Chien-Hsing Chang; Cathelijne Frielink; Habibe Karacay; William J McBride; Celeste Regino; Edmund A Rossi; David M Goldenberg
A new Tri-Fab bispecific antibody for pretargeting Trop-2-expressing epithelial cancers.
David M Goldenberg; Kerstin M Heselmeyer-Haddad; Meiyu Loo; Thomas Ried; David Zagzag; Lissa Y Berroa Garcia; Chien-Hsing Chang; David V Gold
Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo.
Rhona Stein; Pankaj Gupta; Xiaochuan Chen; Thomas M Cardillo; Richard R Furman; Susan Chen; Chien-Hsing Chang; David M Goldenberg
Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways.

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All Publications

2012: Robert M Sharkey; Catharina M van Rij; Otto C Boerman; Thomas M Cardillo; Chien-Hsing Chang; Cathelijne Frielink; Habibe Karacay; William J McBride; Celeste Regino; Edmund A Rossi; David M Goldenberg
A new Tri-Fab bispecific antibody for pretargeting Trop-2-expressing epithelial cancers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(10):1625-32.
2012: David M Goldenberg; Kerstin M Heselmeyer-Haddad; Meiyu Loo; Thomas Ried; David Zagzag; Lissa Y Berroa Garcia; Chien-Hsing Chang; David V Gold
Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo.
International journal of cancer. Journal international du cancer 2012;131(1):49-58.
2010: Rhona Stein; Pankaj Gupta; Xiaochuan Chen; Thomas M Cardillo; Richard R Furman; Susan Chen; Chien-Hsing Chang; David M Goldenberg
Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways.
Blood 2010;115(25):5180-90.
2010: Robert M Sharkey; Edmund A Rossi; William J McBride; Chien-Hsing Chang; David M Goldenberg
Recombinant bispecific monoclonal antibodies prepared by the dock-and-lock strategy for pretargeted radioimmunotherapy.
Seminars in nuclear medicine 2010;40(3):190-203.
2009: David M Goldenberg; Edmund A Rossi; Rhona Stein; Thomas M Cardillo; Myron S Czuczman; Francisco J Hernandez-Ilizaliturri; Hans J Hansen; Chien-Hsing Chang
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.
Blood 2009;113(5):1062-70.
2008: Robert M Sharkey; Habibe Karacay; Samuel Litwin; Edmund A Rossi; William J McBride; Chien-Hsing Chang; David M Goldenberg
Improved therapeutic results by pretargeted radioimmunotherapy of non-Hodgkin's lymphoma with a new recombinant, trivalent, anti-CD20, bispecific antibody.
Cancer research 2008;68(13):5282-90.
2008: David V Gold; David M Goldenberg; Habibe Karacay; Edmund A Rossi; Chien-Hsing Chang; Thomas M Cardillo; William J McBride; Robert M Sharkey
A novel bispecific, trivalent antibody construct for targeting pancreatic carcinoma.
Cancer research 2008;68(12):4819-26.
2008: David M Goldenberg; Edmund A Rossi; Robert M Sharkey; William J McBride; Chien-Hsing Chang
Multifunctional antibodies by the Dock-and-Lock method for improved cancer imaging and therapy by pretargeting.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(1):158-63.
2007: Robert M Sharkey; Habibe Karacay; William J McBride; Edmund A Rossi; Chien-Hsing Chang; David M Goldenberg
Bispecific antibody pretargeting of radionuclides for immuno single-photon emission computed tomography and immuno positron emission tomography molecular imaging: an update.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5577s-5585s.
2007: Rhona Stein; M Jules Mattes; Thomas M Cardillo; Hans J Hansen; Chien-Hsing Chang; Jack Burton; Serengulam V Govindan; David M Goldenberg
CD74: a new candidate target for the immunotherapy of B-cell neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5556s-5563s.
2005: Robert M Sharkey; Thomas M Cardillo; Edmund A Rossi; Chien-Hsing Chang; Habibe Karacay; William J McBride; Hans J Hansen; Ivan D Horak; David M Goldenberg
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody.
Nature medicine 2005;11(11):1250-5.
2005: Robert M Sharkey; Habibe Karacay; Chien-Hsing Chang; William J McBride; Ivan D Horak; David M Goldenberg
Improved therapy of non-Hodgkin's lymphoma xenografts using radionuclides pretargeted with a new anti-CD20 bispecific antibody.
Leukemia 2005;19(6):1064-9.

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