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Cheng-Wei Tom Chang

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Venkatareddy Udumula; Jianjun Zhang; Ka Yee Chan; Marina Y Fosso; Young Wan Ham; Jie Li; Ravi Rai; Cheng-Wei Tom Chang
Investigation of antibacterial mode of action for traditional and amphiphilic aminoglycosides.
Taihei Ito; Takashi Kenmochi; Tomonori Saito; Satoshi Suzuki; Cheng-Wei Tom Chang; Dong Chen; Jon Y Takemoto
Mesobiliverdin IXα Enhances Rat Pancreatic Islet Yield and Function.
Stephen T Lee; Kip E Panter; Kevin D Welch; Jianjun Zhang; Dale R Gardner; Benedict T Green; Cheng-Wei Tom Chang
Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and KAAD-cyclopamine.

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All Publications

2013: Venkatareddy Udumula; Jianjun Zhang; Ka Yee Chan; Marina Y Fosso; Young Wan Ham; Jie Li; Ravi Rai; Cheng-Wei Tom Chang
Investigation of antibacterial mode of action for traditional and amphiphilic aminoglycosides.
Bioorganic & medicinal chemistry letters 2013;23(6):1671-5.
2013: Taihei Ito; Takashi Kenmochi; Tomonori Saito; Satoshi Suzuki; Cheng-Wei Tom Chang; Dong Chen; Jon Y Takemoto
Mesobiliverdin IXα Enhances Rat Pancreatic Islet Yield and Function.
Frontiers in pharmacology 2013;4():50.
2012: Stephen T Lee; Kip E Panter; Kevin D Welch; Jianjun Zhang; Dale R Gardner; Benedict T Green; Cheng-Wei Tom Chang
Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and KAAD-cyclopamine.
Journal of pharmaceutical and biomedical analysis 2012;66():282-6.
2012: Marina Y Fosso; Rylee Gregory; Ka Yee Chan; Cheng-Wei Tom Chang
Library synthesis and antibacterial investigation of cationic anthraquinone analogs.
ACS combinatorial science 2012;14(3):231-5.
2011: Ka Yee Chan; Jianjun Zhang; Cheng-Wei Tom Chang
Mode of action investigation for the antibacterial cationic anthraquinone analogs.
Bioorganic & medicinal chemistry letters 2011;21(21):6353-6.
2011: Jianjun Zhang; Nathan Redman; Anthony Phillip Litke; Jia Zeng; Jixun Zhan; Ka Yee Chan; Cheng-Wei Tom Chang
Synthesis and antibacterial activity study of a novel class of cationic anthraquinone analogs.
Bioorganic & medicinal chemistry 2011;19(1):498-503.
2010: Jianjun Zhang; Anthony Litke; Katherine Keller; Ravi Rai; Cheng-Wei Tom Chang
Synthesis of novel aminoglycosides via allylic azide rearrangement for investigating the significance of 2'-amino group.
Bioorganic & medicinal chemistry 2010;18(4):1396-405.
2009: Jianjun Zhang; Katherine Keller; Jon Y Takemoto; Mekki Bensaci; Anthony Litke; Przemyslaw G Czyryca; Cheng-Wei Tom Chang
Synthesis and combinational antibacterial study of 5''-modified neomycin.
The Journal of antibiotics 2009;62(10):539-44.
2009: Cheng-Wei Tom Chang
Predictable enzymatic glycosylation.
Chemistry & biology 2009;16(6):579-80.
2009: Jianjun Zhang; Cheng-Wei Tom Chang
One-pot synthesis of 1- and 2-substituted naphtho[2,3-d][1,2,3]triazole-4,9-diones.
The Journal of organic chemistry 2009;74(11):4414-7.
2009: Jianjun Zhang; Cheng-Wei Tom Chang
Divergent synthesis of three classes of aryl N-glycosides by solvent control.
The Journal of organic chemistry 2009;74(2):685-95.
2008: Jianjun Zhang; Fang-I Chiang; Long Wu; Przemyslaw Greg Czyryca; Ding Li; Cheng-Wei Tom Chang
Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria.
Journal of medicinal chemistry 2008;51(23):7563-73.
2008: Jianjun Zhang; Massoud Garrossian; Dale Gardner; Arash Garrossian; Young-Tae Chang; Yun Kyung Kim; Cheng-Wei Tom Chang
Synthesis and anticancer activity studies of cyclopamine derivatives.
Bioorganic & medicinal chemistry letters 2008;18(4):1359-63.
2007: Jie Li; Fang-I Chiang; Hsiao-Nung Chen; Cheng-Wei Tom Chang
Synthesis and antibacterial activity of pyranmycin derivatives with N-1 and O-6 modifications.
Bioorganic & medicinal chemistry 2007;15(24):7711-9.
2007: Jie Li; Fang-I Chiang; Hsiao-Nung Chen; Cheng-Wei Tom Chang
Investigation of the regioselectivity for the staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification.
The Journal of organic chemistry 2007;72(11):4055-66.
2007: Jianjun Zhang; Hsiao-Nung Chen; Fang-I Chiang; Jon Y Takemoto; Mekki Bensaci; Cheng-Wei Tom Chang
Sonication-assisted library synthesis of oxazolidinone-carbohydrate conjugates.
Journal of combinatorial chemistry 2007;9(1):17-9.
2006: Shenglou Deng; Umesh Gangadharmath; Cheng-Wei Tom Chang
Sonochemistry: a powerful way of enhancing the efficiency of carbohydrate synthesis.
The Journal of organic chemistry 2006;71(14):5179-85.
2006: Ravi Rai; Hsiao-Nung Chen; Przemyslaw G Czyryca; Jie Li; Cheng-Wei Tom Chang
Design and synthesis of pyrankacin: a pyranmycin class of broad-spectrum aminoglycoside antibiotic.
Organic letters 2006;8(5):887-9.
2006: Stephen T Lee; Kristin Wildeboer; Kip E Panter; William R Kem; Dale R Gardner; Russell J Molyneux; Cheng-Wei Tom Chang; Ferenc Soti; James A Pfister
Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine.
Neurotoxicology and teratology 2006;28(2):220-8.
2005: Jinhua Wang; Jie Li; Hsiao-Nung Chen; Huiwen Chang; Christabel Tomla Tanifum; Hsiu-Hsiang Liu; Przemyslaw G Czyryca; Cheng-Wei Tom Chang
Glycodiversification for the optimization of the kanamycin class aminoglycosides.
Journal of medicinal chemistry 2005;48(20):6271-85.
2005: Jie Li; Hsiao-Nung Chen; Huiwen Chang; Jinhua Wang; Cheng-Wei Tom Chang
Tuning the regioselectivity of the Staudinger reaction for the facile synthesis of kanamycin and neomycin class antibiotics with N-1 modification.
Organic letters 2005;7(14):3061-4.
2005: Stephen T Lee; Russell J Molyneux; Kip E Panter; Cheng-Wei Tom Chang; Dale R Gardner; James A Pfister; Massoud Garrossian
Ammodendrine and N-methylammodendrine enantiomers: isolation, optical rotation, and toxicity.
Journal of natural products 2005;68(5):681-5.
2004: Jinhua Wang; Bryan Elchert; Yu Hui; Jon Y Takemoto; Mekki Bensaci; John Wennergren; Huiwen Chang; Ravi Rai; Cheng-Wei Tom Chang
Synthesis of trehalose-based compounds and their inhibitory activities against Mycobacterium smegmatis.
Bioorganic & medicinal chemistry 2004;12(24):6397-413.
2004: Jinhua Wang; Jie Li; Przemyslaw G Czyryca; Huiwen Chang; Jeff Kao; Cheng-Wei Tom Chang
Synthesis of an unusual branched-chain sugar, 5-C-methyl-L-idopyranose for SAR studies of pyranmycins: implication for the future design of aminoglycoside antibiotics.
Bioorganic & medicinal chemistry letters 2004;14(17):4389-93.
2004: Jie Li; Jinhua Wang; Przemyslaw G Czyryca; Huiwen Chang; Thomas Orsak; Richard Evanson; Cheng-Wei Tom Chang
Application of glycodiversification: expedient synthesis and antibacterial evaluation of a library of kanamycin B analogues.
Organic letters 2004;6(9):1381-4.
2004: Bryan Elchert; Jie Li; Jinhua Wang; Yu Hui; Ravi Rai; Roger Ptak; Priscilla Ward; Jon Y Takemoto; Mekki Bensaci; Cheng-Wei Tom Chang
Application of the synthetic aminosugars for glycodiversification: synthesis and antimicrobial studies of pyranmycin.
The Journal of organic chemistry 2004;69(5):1513-23.
2003: Jie Li; Jinhua Wang; Yu Hui; Cheng-Wei Tom Chang
Exploring the optimal site for modifications of pyranmycins with the extended arm approach.
Organic letters 2003;5(4):431-4.
2002: Cheng-Wei Tom Chang; Yu Hui; Bryan Elchert; Jinhua Wang; Jie Li; Ravi Rai
Pyranmycins, a novel class of aminoglycosides with improved acid stability: the SAR of D-pyranoses on ring III of pyranmycin.
Organic letters 2002;4(26):4603-6.
2002: Jinhua Wang; Jie Li; David Tuttle; Jon Y Takemoto; Cheng-Wei Tom Chang
The Synthesis of L-aminosugar and the studies of L-pyranoses on the ring III of pyranmycins.
Organic letters 2002;4(23):3997-4000.
2002: Yu Hui; Cheng-Wei Tom Chang
Convenient divergent synthesis of a library of trehalosamine analogues.
Organic letters 2002;4(13):2245-8.