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David Chang

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Physiology

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Publications

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Min Zhu; David D Chang; Judith C Gasson; Beth Y Karlan; Lillian Ramos; Romaine E Saxton; Dennis J Slamon
Neutralizing monoclonal antibody to periostin inhibits ovarian tumor growth and metastasis.
Jose A Rodríguez; Miguel A Lopez; Michelle C Thayer; Yunzhe Zhao; Michael Oberholzer; David D Chang; Neville K Kisalu; Manuel L Penichet; Gustavo Helguera; Robijn F Bruinsma; Kent L Hill; Jianwei Miao
Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks.
Rafael G Amado; Michael Wolf; Marc Peeters; Eric Van Cutsem; Salvatore Siena; Daniel J Freeman; Todd Juan; Robert Sikorski; Sid Suggs; Robert Radinsky; Scott D Patterson; David D Chang
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.

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All Publications

2011: Min Zhu; David D Chang; Judith C Gasson; Beth Y Karlan; Lillian Ramos; Romaine E Saxton; Dennis J Slamon
Neutralizing monoclonal antibody to periostin inhibits ovarian tumor growth and metastasis.
Molecular cancer therapeutics 2011;10(8):1500-8.
2009: Jose A Rodríguez; Miguel A Lopez; Michelle C Thayer; Yunzhe Zhao; Michael Oberholzer; David D Chang; Neville K Kisalu; Manuel L Penichet; Gustavo Helguera; Robijn F Bruinsma; Kent L Hill; Jianwei Miao
Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19322-7.
2008: Rafael G Amado; Michael Wolf; Marc Peeters; Eric Van Cutsem; Salvatore Siena; Daniel J Freeman; Todd Juan; Robert Sikorski; Sid Suggs; Robert Radinsky; Scott D Patterson; David D Chang
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(10):1626-34.
2007: Lee S Rosen; Razelle Kurzrock; Marilyn Mulay; Andy Van Vugt; Michelle Purdom; Chaan Ng; Jeffrey Silverman; Antonis Koutsoukos; Yu-Nien Sun; Michael B Bass; Ren Y Xu; Anthony Polverino; Jeffrey S Wiezorek; David D Chang; Robert Benjamin; Roy S Herbst
Safety, pharmacokinetics, and efficacy of AMG 706, an oral multikinase inhibitor, in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(17):2369-76.
2004: Daniela Matei; David D Chang; Meei-Huey Jeng
Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(2):681-90.
2003: Raymond S Maul; Yuhong Song; Kurt Amann; Sachi C Gerbin; Thomas D Pollard; David D Chang
EPLIN regulates actin dynamics by cross-linking and stabilizing filaments.
The Journal of cell biology 2003;160(3):399-407.
2002: Lindsay Gillan; Daniela Matei; David A Fishman; C S Gerbin; Beth Y Karlan; David D Chang
Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility.
Cancer research 2002;62(18):5358-64.
2002: Daniela Matei; Thomas G Graeber; Rae Lynn Baldwin; Beth Y Karlan; Jianyu Rao; David D Chang
Gene expression in epithelial ovarian carcinoma.
Oncogene 2002;21(41):6289-98.
2002: Yuhong Song; Bao Hoang; David D Chang
ROCK-II-induced membrane blebbing and chromatin condensation require actin cytoskeleton.
Experimental cell research 2002;278(1):45-52.
2002: Yuhong Song; Raymond S Maul; C Sachi Gerbin; David D Chang
Inhibition of anchorage-independent growth of transformed NIH3T3 cells by epithelial protein lost in neoplasm (EPLIN) requires localization of EPLIN to actin cytoskeleton.
Molecular biology of the cell 2002;13(4):1408-16.
2002: David D Chang; Bao Hoang; Jenny Liu; Timothy A Springer
Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.
The Journal of biological chemistry 2002;277(10):8140-5.
2001: Jin Zhang; Richard E Clatterbuck; Daniele Rigamonti; David D Chang; Harry C Dietz
Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation.
Human molecular genetics 2001;10(25):2953-60.
2001: Raymond S Maul; C Sachi Gerbin; David D Chang
Characterization of mouse epithelial protein lost in neoplasm (EPLIN) and comparison of mammalian and zebrafish EPLIN.
Gene 2001;262(1-2):155-60.
2000: R S Ismail; Rae Lynn Baldwin; J Fang; Damaris Browning; Beth Y Karlan; Judith C Gasson; David D Chang
Differential gene expression between normal and tumor-derived ovarian epithelial cells.
Cancer research 2000;60(23):6744-9.
2000: Y Song; C Wong; David D Chang
Overexpression of wild-type RhoA produces growth arrest by disrupting actin cytoskeleton and microtubules.
Journal of cellular biochemistry 2000;80(2):229-40.
2000: S Chen; Raymond S Maul; H R Kim; David D Chang
Characterization of the human EPLIN (Epithelial Protein Lost in Neoplasm) gene reveals distinct promoters for the two EPLIN isoforms.
Gene 2000;248(1-2):69-76.
1999: Raymond S Maul; David D Chang
EPLIN, epithelial protein lost in neoplasm.
Oncogene 1999;18(54):7838-41.
1998: Bin Liu; J Liao; X Rao; S A Kushner; CD Chung; David D Chang; Ke Shuai
Inhibition of Stat1-mediated gene activation by PIAS1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10626-31.
1998: David D Chang; No-Hee Park; Christopher T Denny; Stanley F Nelson; M Pe
Characterization of transformation related genes in oral cancer cells.
Oncogene 1998;16(15):1921-30.
1998: J Liliental; David D Chang
Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit.
The Journal of biological chemistry 1998;273(4):2379-83.
1997: David D Chang; C Wong; H Smith; J Liu
ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin.
The Journal of cell biology 1997;138(5):1149-57.

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