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Fang-Rong Chang

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Molecular Structure

Procedures

Drug Screening Assays, Antitumor

Living Beings

Concepts & Ideas

Phenomena

Magnetic Resonance Spectroscopy

Geographic Areas

Taiwan

Co-author Network

Publications

TOP 3
Yu-Chi Tsai; Chin-Chung Wu; Shou-Fang Wu; Yang-Chang Wu; Ming-Hong Yen; Ludger Beerhues; Shang-Yu Chiang; Mohamed El-Shazly; Wan-Chun Lai; Fang-Rong Chang
The oestrogenic and anti-platelet activities of dihydrobenzofuroisocoumarins and homoisoflavonoids from Liriope platyphylla roots.
Fang-Rong Chang; Shu-Li Chen; Yuan-Bin Cheng; Mohamed El-Shazly; Chiao-Ting Yen; Ming-Hong Yen; Cheng-Ying Yu; Yang-Chang Wu
Spirostanoids with 1,4-dien-3-one or 3β,7α-diol-5,6-ene moieties from Solanum violaceum.
Jing-Ru Liou; Chao-Neng Tseng; Chin-Chun Wu; Fang-Rong Chang; Shu-Li Chen; Yueh-Lin Chuang; Ying-Chi Du; Mohamed El-Shazly; Ming-Feng Hou; Pei-Wen Hsieh; Yu-Ming Hsu; Tsong-Long Hwang; Yang-Chang Wu
1,5-Diphenylpent-3-en-1-ynes and methyl naphthalene carboxylates from Lawsonia inermis and their anti-inflammatory activity.

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All Publications

2013: Yu-Chi Tsai; Chin-Chung Wu; Shou-Fang Wu; Yang-Chang Wu; Ming-Hong Yen; Ludger Beerhues; Shang-Yu Chiang; Mohamed El-Shazly; Wan-Chun Lai; Fang-Rong Chang
The oestrogenic and anti-platelet activities of dihydrobenzofuroisocoumarins and homoisoflavonoids from Liriope platyphylla roots.
Food chemistry 2013;140(1-2):305-14.
2013: Fang-Rong Chang; Shu-Li Chen; Yuan-Bin Cheng; Mohamed El-Shazly; Chiao-Ting Yen; Ming-Hong Yen; Cheng-Ying Yu; Yang-Chang Wu
Spirostanoids with 1,4-dien-3-one or 3β,7α-diol-5,6-ene moieties from Solanum violaceum.
Bioorganic & medicinal chemistry letters 2013;23(9):2738-42.
2013: Jing-Ru Liou; Chao-Neng Tseng; Chin-Chun Wu; Fang-Rong Chang; Shu-Li Chen; Yueh-Lin Chuang; Ying-Chi Du; Mohamed El-Shazly; Ming-Feng Hou; Pei-Wen Hsieh; Yu-Ming Hsu; Tsong-Long Hwang; Yang-Chang Wu
1,5-Diphenylpent-3-en-1-ynes and methyl naphthalene carboxylates from Lawsonia inermis and their anti-inflammatory activity.
Phytochemistry 2013;88():67-73.
2013: Yang-Chang Wu; Yi-Hsiu Wu; Yu-Hsuan Lan; Munisamy Sureshbabu; Fang-Rong Chang; Ya-Wen Chang; Yao-Ching Fang; Tsong-Long Hwang
Potent inhibition of human neutrophil activations by bractelactone, a novel chalcone from Fissistigma bracteolatum.
Toxicology and applied pharmacology 2013;266(3):399-407.
2013: Chien-Chih Chiu; Chon-Kit Chou; Jo-Wen Haung; Hsuan-Min Huang; Hurng-Wern Huang; Kuang-Jing Huang; Yang-Chang Wu; Fang-Rong Chang; Hsueh-Wei Chang
Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways.
PloS one 2013;8(5):e64739.
2013: Kuan-Jen Chen; Wei-Chun Chen; Fang-Rong Chang; Hsueh-Wei Chang; Chin-Kai Tseng; Shou-Fang Wu; Jin-Iong Yang; Chi-Chen Yeh; Jin-Ching Lee
Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation.
PloS one 2013;8(2):e57704.
2012: Ming-Wei Lin; Sophie S W Wang; deng-chyang wu; Yang-Chang Wu; Fang-Rong Chang; An-Shen Lin; Yaw-Bin Huang
Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(12):4333-9.
2012: Fang-Rong Chang; Mohamed Ei-Shazly; Kuei-Hsiang Lin; Wen-Hsun Lin; Chiao-Ting Yen; Ming-Hong Yen; Yang-Chang Wu
Anti-human coronavirus (anti-HCoV) triterpenoids from the leaves of Euphorbia neriifolia.
Natural product communications 2012;7(11):1415-7.
2012: Chih-Hui Yang; Chih-Yu Wang; Fang-Rong Chang; Yi-Yao Hsu; Keng-Shiang Huang; Yung-Sheng Lin
Microfluidic-assisted synthesis of hemispherical and discoidal chitosan microparticles at an oil/water interface.
Electrophoresis 2012;33(21):3173-80.
2012: Ching-Yu Yen; Chi-Chen Yeh; Fang-Rong Chang; Hsueh-Wei Chang; Kuo-Feng Chang; Chien-Chih Chiu; Rou-Wen Haung; You-Cheng Hseu; Kuang-Jing Huang; Yang-Chang Wu
Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction.
Mutation research 2012;747(2):253-8.
2012: B Danko; Leonard Amaral; Fang-Rong Chang; D W Chuang; Ana Martins; Joseph Molnár; H C Wang; Yang-Chang Wu; Attila Hunyadi
In vitro cytotoxic activity of novel protoflavone analogs - selectivity towards a multidrug resistant cancer cell line.
Anticancer research 2012;32(7):2863-9.
2012: Hui-Chun Wang; Chin-Chung Wu; Fang-Rong Chang; Wen-Cheng Chou; Da-Wei Chuang; Attila Hunyadi; Alan Yueh-Luen Lee; Wen-Lien Lin; Kevin Yen-Ting Liu; Chao-Neng Tseng; Yang-Chang Wu
Inhibition of ATR-dependent signaling by protoapigenone and its derivative sensitizes cancer cells to interstrand cross-link-generating agents in vitro and in vivo.
Molecular cancer therapeutics 2012;11(7):1443-53.
2012: Chi-Ting Hsieh; Tusty-Jiuan Hsieh; Yi-Hong Tsai; Shou-Fang Wu; Yang-Chang Wu; Chiao-Ting Yen; Da-Wei Chuang; Mohamed El-Shazly; Fang-Rong Chang
Synthesis of chalcone derivatives as potential anti-diabetic agents.
Bioorganic & medicinal chemistry letters 2012;22(12):3912-5.
2012: Ying-Chi Du; Mohamed El-Shazly; Yu-Ming Hsu; Yi-Hsin Lin; Yan-Yu Lin; Fang-Rong Chang; Chieh-Fu Chen; Ping-Jyun Sung; Tung-Ying Wu; Yang-Chang Wu; Mei-Chin Lu
Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2012;19(8-9):788-96.
2012: Chin-Lin Hsu; Pei-Yu Tseng; Fang-Rong Chang; Yi-Fen Chen; Ying-Chi Du; Mohamed El-Shazly; Song-Chwan Fang
Geranyl flavonoid derivatives from the fresh leaves of Artocarpus communis and their anti-inflammatory activity.
Planta medica 2012;78(10):995-1001.
2012: S-F Wu; Yang-Chang Wu; Fang-Rong Chang; Y-S Chuang; C-K Lin; C-K Tseng; J-C Lee
Anti-hepatitis C virus activity of 3-hydroxy caruilignan C from Swietenia macrophylla stems.
Journal of viral hepatitis 2012;19(5):364-70.
2012: Tung-Ying Wu; I-Hui Yang; Fang-Rong Chang; Tusty-Jiuan Hsieh; Robert Shiurba; Yao-Ting Tsai; Jaw-Yan Wang; Wei-Chiao Chang
Isodesacetyluvaricin, an Annonaceous acetogenin, specifically inhibits gene expression of cyclooxygenase-2.
Journal of natural products 2012;75(4):572-6.
2012: Chiao-Ting Yen; Hsin-Fu Yen; Fang-Rong Chang; Chao-Jung Chen; Shu-Li Chen; Tsong-Long Hwang; Chia-Lin Lee; Yang-Chang Wu
Indiosides G-K: steroidal glycosides with cytotoxic and anti-inflammatory activities from Solanum violaceum.
Journal of natural products 2012;75(4):636-43.
2012: Sung-Fei Hsieh; Tain-Jye Hsieh; Tsong-Long Hwang; Chin-Chung Wu; Yang-Chang Wu; Ying-Chi Du; Mohamed El-Shazly; Fang-Rong Chang
Chemical constituents from Farfugium japonicum var. formosanum.
Natural product communications 2012;7(4):435-40.
2012: Chin-San Liu; Yang-Chang Wu; Chen-Chia Chang; Fang-Rong Chang; Wei-Chiao Chang; Ying-Chi Du; Tusty-Jiuan Hsieh
2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation of human aortic smooth muscle cells by increasing the expression of peroxisome proliferator-activated receptor gamma.
Journal of cardiovascular pharmacology 2012;59(4):339-51.
2012: Chia-Chun Hsu; Wei-Kung Tseng; Chau-Chung Wu; Yang-Chang Wu; Ying-Chi Du; Lynn Farh; Fang-Rong Chang
Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(3-4):619-24.
2012: Tusty-Jiuan Hsieh; Min-Chun Liao; Pei-Jung Lien; Chuan-Chia Sun; Yi-Hong Tsai; Fang-Rong Chang; Ying-Chi Du; Yang-Chang Wu
Anti-diabetic properties of non-polar Toona sinensis Roem extract prepared by supercritical-CO2 fluid.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(3-4):779-89.
2012: Ying-Chi Du; Ming-Feng Hou; Yu-Ming Hsu; Wan-Yu Lin; Chi-Yu Lu; Mei-Chin Lu; Ya-Ting Tsui; Tung-Ying Wu; Fang-Rong Chang; Hsuan-Lun Chen; Fu-Ting Cheng; Ming-Hong Yen; Yang-Chang Wu
Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata.
Journal of pharmaceutical and biomedical analysis 2012;58():182-92.
2012: Teigo Asai; Fang-Rong Chang; Yu-Ming Chung; Tomoji Ozeki; Hiroaki Sakurai; Kouwa Yamashita; Yoshiteru Oshima
Tenuipyrone, a novel skeletal polyketide from the entomopathogenic fungus, Isaria tenuipes, cultivated in the presence of epigenetic modifiers.
Organic letters 2012;14(2):513-5.
2012: Chi-Chen Yeh; Fang-Rong Chang; Yi Fang; Hurng-Wern Huang; Jen-Yang Tang; Chao-Neng Tseng; Jing-Iong Yang; Hsueh-Wei Chang
Antiproliferation and induction of apoptosis in Ca9-22 oral cancer cells by ethanolic extract of Gracilaria tenuistipitata.
Molecules (Basel, Switzerland) 2012;17(9):10916-27.
2012: Chi-Chen Yeh; Ya-Ching Chan; Fang-Rong Chang; Li-Yeh Chuang; You-Cheng Hseu; Hurng-Wern Huang; Jin-Ching Lee; Jen-Yang Tang; Chao-Neng Tseng; Jing-Iong Yang; Hsueh-Wei Chang
Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress.
BMC complementary and alternative medicine 2012;12():142.
2012: Hui-Chun Wang; Yang-Chang Wu; Fang-Rong Chang; Wen-Ying Chen; Mei-Hsin Liu; Yi-Ling Tsai; Chin-Chung Wu
Withanolides-induced breast cancer cell death is correlated with their ability to inhibit heat protein 90.
PloS one 2012;7(5):e37764.
2012: Chia-Lin Lee; Ying-Ting Lin; Juan-Chang Yang; Anders Backlund; Fang-Rong Chang; Guan-Yu Chen; Shu-Li Chen; Yang-Chang Wu
Synthesis and biological evaluation of phenanthrenes as cytotoxic agents with pharmacophore modeling and ChemGPS-NP prediction as topo II inhibitors.
PloS one 2012;7(5):e37897.
2012: Yung-Sheng Lin; Chih-Yu Wang; Chih-Hui Yang; Fang-Rong Chang; Keng-Shiang Huang; Wan-Chen Hsieh
An aluminum microfluidic chip fabrication using a convenient micromilling process for fluorescent poly(DL-lactide-co-glycolide) microparticle generation.
Sensors (Basel, Switzerland) 2012;12(2):1455-67.
2011: Yi-Hsiung Lin; Yang-Chang Wu; Fang-Rong Chang; Wen-Hsin Chang; Chien-Chih Lee; Jan-Gowth Chang
16-hydroxycleroda-3,13-dien-15,16-olide regulates the expression of histone-modifying enzymes PRC2 complex and induces apoptosis in CML K562 cells.
Life sciences 2011;89(23-24):886-95.
2011: Wen-Ying Chen; Yu-An Hsieh; Ya-Fei Kang; Ching-I Tsai; Fang-Rong Chang; Yang-Chang Wu; Chin-Chung Wu
Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π.
Investigational new drugs 2011;29(6):1347-59.
2011: Yu-Min Ko; Tung-Ying Wu; Yang-Chang Wu; Fang-Rong Chang; Jinn-Yuh Guh; Lea-Yea Chuang
Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor-α-related pathways in MCF-7 cells.
Journal of ethnopharmacology 2011;137(3):1283-90.
2011: Jyh-Ying Peng; Yuh-Show Tsai; Yang-Chang Wu; Fang-Rong Chang; Yen-Jen Chen; Chung-Chien Chou; Yi-Hung Huang; Lung-Sen Kao; Chung-Chih Lin; Young-Chau Liu; Chun-Nan Hsu
Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics.
PLoS computational biology 2011;7(10):e1002212.
2011: Kung-Kai Kuo; Yu-Hsuan Lan; Chien-Feng Li; Fang-Rong Chang; Lih-Ren Chen; Yi-Ling Chen; Yang-Chang Wu; Yow-Ling Shiue
Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells.
Toxicology and applied pharmacology 2011;256(1):8-23.
2011: Shou-Fang Wu; Fang-Rong Chang; Shu-Li Chen; Tsong-Long Hwang; Kuo-Hsiung Lee; Emika Ohkoshi; Chin-Chung Wu; Yang-Chang Wu
Bioactive components from the heartwood of Pterocarpus santalinus.
Bioorganic & medicinal chemistry letters 2011;21(18):5630-2.
2011: Yu-Ming Chung; Mohamed El-Shazly; Chia-Lin Lee; Yann-Lii Leu; Hui-Chun Wang; Fang-Rong Chang; Ming-Ching Cheng; Yang-Chang Wu
Antioxidant and tyrosinase inhibitory constituents from a desugared sugar cane extract, a byproduct of sugar production.
Journal of agricultural and food chemistry 2011;59(17):9219-25.
2011: Wan-Chun Lai; Hiroshi Nozaki; Hui-Chun Wang; Chih-Chung Wu; Yang-Chang Wu; Juan-Cheng Yang; Guan-Yu Chen; Ken-Ichiro Hayashi; Chia-Jung Hsieh; Michal Korinek; Fang-Rong Chang
Using the pER8:GUS reporter system to screen for phytoestrogens from Caesalpinia sappan.
Journal of natural products 2011;74(8):1698-706.
2011: Juan-Cheng Yang; Fang-Rong Chang; Guan-Yu Chen; Chia-Lin Lee; Yan-Yu Lin; Mei-Chin Lu; Yang-Chang Wu
Selective targeting of breast cancer cells through ROS-mediated mechanisms potentiates the lethality of paclitaxel by a novel diterpene, gelomulide K.
Free radical biology & medicine 2011;51(3):641-57.
2011: Shou-Fang Wu; Fang-Rong Chang; Sheng-Yang Wang; Tsong-Long Hwang; Chia-Lin Lee; Shu-Li Chen; Chin-Chung Wu; Yang-Chang Wu
Anti-inflammatory and cytotoxic neoflavonoids and benzofurans from Pterocarpus santalinus.
Journal of natural products 2011;74(5):989-96.
2011: Huei-Mei Chen; Fang-Rong Chang; Ya-Ching Hsieh; Yu-Jen Cheng; Kun-Chou Hsieh; Lih-Min Tsai; An-Shen Lin; Yang-Chang Wu; Shyng-Shiou F Yuan
A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.
Free radical biology & medicine 2011;50(9):1151-62.
2011: Chien-Chih Chiu; Po-Len Liu; Kuang-Jing Huang; Hui-Min Wang; Kuo-Feng Chang; Chon-Kit Chou; Fang-Rong Chang; Inn-Wen Chong; Kang Fang; Jia-Shing Chen; Hsueh-Wei Chang; Yang-Chang Wu
Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability.
Journal of agricultural and food chemistry 2011;59(8):4288-93.
2011: Pei-Yu Yang; Ming-Feng Chen; Ying-Hsien Kao; Dan-Ning Hu; Fang-Rong Chang; Yang-Chang Wu
Norcantharidin induces apoptosis of breast cancer cells: involvement of activities of mitogen activated protein kinases and signal transducers and activators of transcription.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(3):699-707.
2011: Yu-Ming Chung; Fang-Rong Chang; Tseng-Fu Tseng; Tsann-Long Hwang; Lei-Chin Chen; Shou-Fang Wu; Chia-Lin Lee; Zu-Yau Lin; Li-Yeh Chuang; Jinu-Huang Su; Yang-Chang Wu
A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis.
Bioorganic & medicinal chemistry letters 2011;21(6):1792-4.
2011: Mei-Hui Lin; Fang-Rong Chang; Mu-Yi Hua; Yang-Chang Wu; Shih-Tung Liu
Inhibitory effects of 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose on biofilm formation by Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2011;55(3):1021-7.
2011: Chia-Lin Lee; Chi-Huan Huang; Hui-Chun Wang; Da-Wei Chuang; Ming-Jung Wu; Sheng-Yang Wang; Tsong-Long Hwang; Chin-Chung Wu; Yeh-Long Chen; Fang-Rong Chang; Yang-Chang Wu
First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents.
Organic & biomolecular chemistry 2011;9(1):70-3.
2011: Attila Hunyadi; Chia-Lin Lee; Hui-Chun Wang; Chin-Chung Wu; Fang-Rong Chang; Michael Y Chiang; Da-Wei Chuang; Balazs Danko; Yang-Chang Wu
Direct semi-synthesis of the anticancer lead-drug protoapigenone from apigenin, and synthesis of further new cytotoxic protoflavone derivatives.
PloS one 2011;6(8):e23922.
2011: Chia-Yu Chang; Tain-Junn Cheng; Fang-Rong Chang; Hsien-Yi Wang; Wei-Chih Kan; Shun-Lai Li; Li-Hsueh Huang; Yu-Chun Chen; Wan-Chen Tsai; Chia-Hsin Huang; Chia-Hui Cheng; Guo-Yang Lee; Shiang-Wei Shyue; Yi-Peng Chen; Kao-Chang Lin; Jiunn-Jye Chuu
Macrophage mediated anti-proliferation effects of Anthodia camphorata non-polysaccharide based extracts on human hepatoma cells.
Bioscience, biotechnology, and biochemistry 2011;75(4):624-32.
2011: Jin-Ching Lee; Wei-Chun Chen; Shou-Fang Wu; Chin-Kai Tseng; Ching-Yi Chiou; Fang-Rong Chang; Shih-hsien Hsu; Yang-Chang Wu
Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2.
Antiviral research 2011;89(1):35-42.
2010: Chia-Lin Lee; Yung-Chih Liao; Tsong-Long Hwang; Chin-Chung Wu; Fang-Rong Chang; Yang-Chang Wu
Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.
Bioorganic & medicinal chemistry letters 2010;20(24):7354-7.
2010: Chih-Chuang Liaw; Tung-Ying Wu; Fang-Rong Chang; Yang-Chang Wu
Historic perspectives on Annonaceous acetogenins from the chemical bench to preclinical trials.
Planta medica 2010;76(13):1390-404.
2010: Pei-Yu Yang; Ming-Feng Chen; Chi-Hong Tsai; Dan-Ning Hu; Fang-Rong Chang; Yang-Chang Wu
Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(3):766-75.
2010: Fang-Rong Chang; Yi-Chung Hsieh; Yung-Fu Chang; Kuo-Hsiung Lee; Yang-Chang Wu; Li-Kwan Chang
Inhibition of the Epstein-Barr virus lytic cycle by moronic acid.
Antiviral research 2010;85(3):490-5.
2010: Chiao-Ting Yen; Kyoko Goto; Tsong-Long Hwang; Pei-Chi Wu; Susan L Morris-Natschke; Wan-Chun Lai; Kenneth F Bastow; Fang-Rong Chang; Yang-Chang Wu; Kuo-Hsiung Lee
Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents.
Bioorganic & medicinal chemistry letters 2010;20(3):1037-9.
2010: Yu-Tzu Shih; Ya-Yun Hsu; Fang-Rong Chang; Yang-Chang Wu; Yi-Ching Lo
6-Hydroxycleroda-3,13-dien-15,16-olide protects neuronal cells from lipopolysaccharide-induced neurotoxicity through the inhibition of microglia-mediated inflammation.
Planta medica 2010;76(2):120-7.
2010: Ching-Yu Yen; Chien-Chih Chiu; Fang-Rong Chang; Jeff Yi-Fu Chen; Chi-Ching Hwang; You-Cheng Hseu; Hsin-Ling Yang; Alan Yueh-Luen Lee; Ming-Tz Tsai; Zong-Lun Guo; Yu-Shan Cheng; Yin-Chang Liu; Yu-Hsuan Lan; Yu-Ching Chang; Ying-Chin Ko; Hsueh-Wei Chang; Yang-Chang Wu
4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest.
BMC cancer 2010;10():46.
2009: Huei-Mei Chen; Yang-Chang Wu; Yi-Chen Chia; Fang-Rong Chang; Hseng-Kuang Hsu; Ya-Ching Hsieh; Chih-Chen Chen; Shyng-Shiou F Yuan
Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.
Cancer letters 2009;286(2):161-71.
2009: Chien-Chih Chiu; Hsueh-Wei Chang; Da-Wei Chuang; Fang-Rong Chang; Yu-Ching Chang; Yu-Shan Cheng; Ming-Tz Tsai; Wan-Yu Chen; Su-Shuo Lee; Chih-Kuang Wang; Jeff Yi-Fu Chen; Hui-Min Wang; Chao-Chieh Chen; Yin-Chang Liu; Yang-Chang Wu
Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299.
DNA and cell biology 2009;28(10):501-6.
2009: Chia-Lin Lee; Lien-Chai Chiang; Li-Hung Cheng; Chih-Chuang Liaw; Mohamed H Abd El-Razek; Fang-Rong Chang; Yang-Chang Wu
Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida.
Journal of natural products 2009;72(9):1568-72.
2009: Yu-Yi Hou; Mu-Ling Wu; Yu-Chun Hwang; Fang-Rong Chang; Yang-Chang Wu; Chin-Chung Wu
The natural diterpenoid ovatodiolide induces cell cycle arrest and apoptosis in human oral squamous cell carcinoma Ca9-22 cells.
Life sciences 2009;85(1-2):26-32.
2009: I-Hsiao Chen; Mei-Chin Lu; Ying-Chi Du; Ming-Hong Yen; Chin-Chung Wu; Yung-Husan Chen; Chih-Sheng Hung; Shu-Li Chen; Fang-Rong Chang; Yang-Chang Wu
Cytotoxic triterpenoids from the stems of Microtropis japonica.
Journal of natural products 2009;72(7):1231-6.
2009: Ying-Chi Du; An-Shen Lin; Chin-Chung Wu; Pei-Wen Hsieh; Yung-Husan Chen; I-Hsiao Chen; Shu-Li Chen; Hsin-Fu Yen; Tilo Lübken; Fang-Rong Chang; Yang-Chang Wu
New cytotoxic lupane triterpenes from Perrottetia arisanensis.
Planta medica 2009;75(8):848-55.
2009: Chiao-Ting Yen; Pei-Wen Hsieh; Tsann-Long Hwang; Yu-Hsuan Lan; Fang-Rong Chang; Yang-Chang Wu
Flavonol glycosides from Muehlenbeckia platyclada and their anti-inflammatory activity.
Chemical & pharmaceutical bulletin 2009;57(3):280-2.
2009: Chia-Lin Lee; Fang-Rong Chang; Ming-Hon Yen; Donglei Yu; Yi-Nan Liu; Kenneth F Bastow; Susan L Morris-Natschke; Yang-Chang Wu; Kuo-Hsiung Lee
Cytotoxic phenanthrenequinones and 9,10-dihydrophenanthrenes from Calanthe arisanensis.
Journal of natural products 2009;72(2):210-3.
2009: An-Shen Lin; Chia-Rong Lin; Ying-Chi Du; Tilo Lübken; Michael Y Chiang; I-Hsiao Chen; Chin-Chung Wu; Tsong-Long Hwang; Shu-Li Chen; Ming-Hong Yen; Fang-Rong Chang; Yang-Chang Wu
Acasiane A and B and farnesirane A and B, diterpene derivatives from the roots of Acacia farnesiana.
Planta medica 2009;75(3):256-61.
2009: Mei-Chin Lu; Ying-Chi Du; Jiunn-Jye Chuu; Shiuh-Lin Hwang; Pao-Chuan Hsieh; Chih-Sheng Hung; Fang-Rong Chang; Yang-Chang Wu
Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A.
Archives of toxicology 2009;83(2):121-9.
2009: Nan Wu; Kuang Fu; Yu-Jie Fu; Yuangang Zu; Fang-Rong Chang; Yung-Husan Chen; Xiao-Lei Liu; Yu Kong; Wei Liu; Cheng-Bo Gu
Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves.
Molecules (Basel, Switzerland) 2009;14(3):1032-43.
2008: Pei-Hsuan Chuang; Pei-Wen Hsieh; Yu-Liang Yang; Kuo-Feng Hua; Fang-Rong Chang; Jentaie Shiea; Shih-Hsiung Wu; Yang-Chang Wu
Cyclopeptides with anti-inflammatory activity from seeds of Annona montana.
Journal of natural products 2008;71(8):1365-70.
2008: Chia-Lin Lee; Kyoko Goto; Donglei Yu; Yi-Nan Liu; Kenneth F Bastow; Susan L Morris-Natschke; Fang-Rong Chang; Yang-Chang Wu; Kuo-Hsiung Lee
Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis.
Bioorganic & medicinal chemistry letters 2008;18(15):4275-7.
2008: Chia-Lin Lee; Po-Ching Huang; Pei-Wen Hsieh; Tsann-Long Hwang; Yu-Yi Hou; Fang-Rong Chang; Yang-Chang Wu
(-)-Xanthienopyran, a new inhibitor of superoxide anion generation by activated neutrophils, and further constituents of the seeds of Xanthium strumarium.
Planta medica 2008;74(10):1276-9.
2008: I-Hsiao Chen; Ying-Chi Du; Mei-Chin Lu; An-Shen Lin; Pei-Wen Hsieh; Chin-Chung Wu; Shu-Li Chen; Hsin-Fu Yen; Fang-Rong Chang; Yang-Chang Wu
Lupane-type triterpenoids from Microtropis fokienensis and Perrottetia arisanensis and the apoptotic effect of 28-hydroxy-3-oxo-lup-20(29)-en-30-al.
Journal of natural products 2008;71(8):1352-7.
2008: Yu-Li Chen; Yu-Hsuan Lan; Pei-Wen Hsieh; Chin-Chung Wu; Shu-Li Chen; Chiao-Ting Yen; Fang-Rong Chang; Wen-Chun Hung; Yang-Chang Wu
Bioactive cembrane diterpenoids of Anisomeles indica.
Journal of natural products 2008;71(7):1207-12.
2008: Wen-Ying Chen; Fang-Rong Chang; Zih-You Huang; Jyun-Hong Chen; Yang-Chang Wu; Chin-Chung Wu
Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins.
The Journal of biological chemistry 2008;283(25):17184-93.
2008: Yu-Lin Yang; Shan-Yu Chang; Hsiang-Chun Teng; Yi-Shiuan Liu; Tao-Chen Lee; Lea-Yea Chuang; Jinn-Yuh Guh; Fang-Rong Chang; Tung-Nan Liao; Jau-Shyang Huang; Jeng-Hsien Yeh; Wen-Teng Chang; Min-Yuan Hung; Ching-Jen Wang; Tai-An Chiang; Chien-Ya Hung; Tsung-Jen Hung
Safflower extract: a novel renal fibrosis antagonist that functions by suppressing autocrine TGF-beta.
Journal of cellular biochemistry 2008;104(3):908-19.
2008: Han-Lin Chang; Fang-Rong Chang; Jin-Shan Chen; Hui-Po Wang; Yi-Hsiu Wu; Chien-Chiao Wang; Yang-Chang Wu; Tsann-Long Hwang
Inhibitory effects of 16-hydroxycleroda-3,13(14)E-dien-15-oic acid on superoxide anion and elastase release in human neutrophils through multiple mechanisms.
European journal of pharmacology 2008;586(1-3):332-9.
2008: Chih-Chuang Liaw; Yu-Liang Yang; Mei Chen; Fang-Rong Chang; Shu-Li Chen; Shih-Hsiung Wu; Yang-Chang Wu
Mono-tetrahydrofuran annonaceous acetogenins from Annona squamosa as cytotoxic agents and calcium ion chelators.
Journal of natural products 2008;71(5):764-71.
2008: Yu-Liang Yang; Kuo-Feng Hua; Pei-Hsuan Chuang; Shih-Hsiung Wu; Kuen-Yuh Wu; Fang-Rong Chang; Yang-Chang Wu
New cyclic peptides from the seeds of Annona squamosa L. and their anti-inflammatory activities.
Journal of agricultural and food chemistry 2008;56(2):386-92.
2008: Shou-Fang Wu; Pei-Wen Hsieh; Chin-Chung Wu; Chia-Lin Lee; Shu-Li Chen; Chi-Yu Lu; Tian-Shung Wu; Fang-Rong Chang; Yang-Chang Wu
Camptothecinoids from the seeds of Taiwanese Nothapodytes foetida.
Molecules (Basel, Switzerland) 2008;13(6):1361-71.
2008: Yung-Husan Chen; Fang-Rong Chang; Mei-Chin Lu; Pei-Wen Hsieh; Ming-Jiuan Wu; Ying-Chi Du; Yang-Chang Wu
New benzoyl glucosides and cytotoxic pterosin sesquiterpenes from Pteris ensiformis Burm.
Molecules (Basel, Switzerland) 2008;13(2):255-66.
2008: Yi-Chen Chia; Fang-Rong Chang; Jinn-Chyi Wang; Chin-Chung Wu; Michael Y-N Chiang; Yu-Hsuan Lan; Keh-Shaw Chen; Yang-Chang Wu
Antiplatelet aggregation coumarins from the leaves of Murraya omphalocarpa.
Molecules (Basel, Switzerland) 2008;13(1):122-8.
2008: Chia-Lin Lee; Fang-Rong Chang; Pei-Wen Hsieh; Michael-Y Chiang; Chin-Chung Wu; Zih-You Huang; Yu-Hsuan Lan; Mei Chen; Kuo-Hsiung Lee; Hsin-Fu Yen; Wen-Chun Hung; Yang-Chang Wu
Cytotoxic ent-abietane diterpenes from Gelonium aequoreum.
Phytochemistry 2008;69(1):276-87.
2007: Yu-Hsuan Lan; Hsin-Yu Wang; Chin-Chung Wu; Shu-Li Chen; Chao-Lin Chang; Fang-Rong Chang; Yang-Chang Wu
New constituents from stems of Artabotrys uncinatus.
Chemical & pharmaceutical bulletin 2007;55(11):1597-9.
2007: Yu-Liang Yang; Sue-Ming Chang; Ching-Chung Wu; Pei-Wen Hsieh; Shu-Li Chen; Fang-Rong Chang; Wen-Chun Hung; Hamad H Issa; Yang-Chang Wu
Cytotoxic sesquiterpene lactones from Pseudoelephantopus spicatus.
Journal of natural products 2007;70(11):1761-5.
2007: An-Shen Lin; Kyoko Goto; Fang-Rong Chang; Donglei Yu; Susan L Morris-Natschke; Chin-Chung Wu; Shu-Li Chen; Yang-Chang Wu; Kuo-Hsiung Lee
First total synthesis of protoapigenone and its analogues as potent cytotoxic agents.
Journal of medicinal chemistry 2007;50(16):3921-7.
2007: Yu-Lin Yang; Shyh-Horng Lin; Lea-Yea Chuang; Jinn-Yuh Guh; Tung-Nan Liao; Tao-Chen Lee; Wen-Teng Chang; Fang-Rong Chang; Min-Yuan Hung; Tai-An Chiang; Chien-Ya Hung
CD36 is a novel and potential anti-fibrogenic target in albumin-induced renal proximal tubule fibrosis.
Journal of cellular biochemistry 2007;101(3):735-44.
2007: Hui-Chiu Chang; Fang-Rong Chang; Yu-Chu Wang; Mei-Ren Pan; Wen-Chun Hung; Yang-Chang Wu
A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression.
Molecular cancer therapeutics 2007;6(5):1572-8.
2007: Pei-Wen Hsieh; Zih-You Huang; Jyun-Hong Chen; Fang-Rong Chang; Ching-Chung Wu; Yu-Liang Yang; Michael Y Chiang; Ming-Hon Yen; Shu-Li Chen; Hsin-Fu Yen; Tilo Lübken; Wen-Chun Hung; Yang-Chang Wu
Cytotoxic withanolides from Tubocapsicum anomalum.
Journal of natural products 2007;70(5):747-53.
2007: An-Shen Lin; Fang-Rong Chang; Hsin-Fu Yen; HannaMaria Björkeborn; Per Norlén; Yang-Chang Wu
Novel flavonoids of Thelypteris torresiana.
Chemical & pharmaceutical bulletin 2007;55(4):635-7.
2006: I-Hsiao Chen; Fang-Rong Chang; Chin-Chung Wu; Shu-Li Chen; Pei-Wen Hsieh; Hsin-Fu Yen; Ying-Chi Du; Yang-Chang Wu
Cytotoxic triterpenoids from the leaves of Microtropis fokienensis.
Journal of natural products 2006;69(11):1543-6.
2006: Hamad H Issa; Sue-Ming Chang; Yu-Liang Yang; Fang-Rong Chang; Yang-Chang Wu
New sesquiterpene lactones from the aerial parts of Pseudoelephantopus spicatus.
Chemical & pharmaceutical bulletin 2006;54(11):1599-601.
2006: Fang-Rong Chang; Tsann-Long Hwang; Yu-Liang Yang; Chia-En Li; Chin-Chung Wu; Hamad H Issa; Wen-Bin Hsieh; Yang-Chang Wu
Anti-inflammatory and cytotoxic diterpenes from formosan Polyalthia longifolia var. pendula.
Planta medica 2006;72(14):1344-7.
2006: Yi-Chen Chia; Fang-Rong Chang; Chin-Chung Wu; Che-Ming Teng; Keh-Shaw Chen; Yang-Chang Wu
Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro.
Planta medica 2006;72(13):1238-41.
2006: Donglei Yu; Yojiro Sakurai; Chin-Ho Chen; Fang-Rong Chang; Li Huang; Yoshiki Kashiwada; Kuo-Hsiung Lee
Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.
Journal of medicinal chemistry 2006;49(18):5462-9.
2006: Yu-Hsuan Lan; Fang-Rong Chang; Yu-Liang Yang; Yang-Chang Wu
New constituents from stems of Goniothalamus amuyon.
Chemical & pharmaceutical bulletin 2006;54(7):1040-3.
2006: Fang-Rong Chang; I-Hsiao Chen; Sin-Chung Liao; Hamad H Issa; Ken-ichiro Hayashi; Hiroshi Nozaki; Yang-Chang Wu; Kuo-Hsiung Lee
Three new agarofuran sesquiterpenes reissantins F-H from Reissantia buchananii.
Planta medica 2006;72(1):92-6.
2006: Yung-Husan Chen; Fang-Rong Chang; Chin-Chung Wu; Ming-Hon Yen; Chih-Chuang Liaw; Hui-Chi Huang; Yueh-Hsiung Kuo; Yang-Chang Wu
New cytotoxic 6-oxygenated 8,9-dihydrofurocoumarins, hedyotiscone A - C, from Hedyotis biflora.
Planta medica 2006;72(1):75-8.
2005: Wen-Ying Chen; Chin-Chung Wu; Yu-Hsuan Lan; Fang-Rong Chang; Che-Ming Teng; Yang-Chang Wu
Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells.
European journal of pharmacology 2005;522(1-3):20-9.
2005: Shang-Hsin Yeh; Fang-Rong Chang; Yang-Chang Wu; Yu-Liang Yang; Shi-Kai Zhuo; Tsann-Long Hwang
An anti-inflammatory ent-kaurane from the stems of Annona squamosa that inhibits various human neutrophil functions.
Planta medica 2005;71(10):904-9.
2005: Michael C Roy; Fang-Rong Chang; Hsiao-Chu Huang; Michael Y-N Chiang; Yang-Chang Wu
Cytotoxic principles from the formosan milkweed, Asclepias curassavica.
Journal of natural products 2005;68(10):1494-9.
2005: An-Shen Lin; Fang-Rong Chang; Chin-Chung Wu; Chih-Chuang Liaw; Yang-Chang Wu
New cytotoxic flavonoids from Thelypteris torresiana.
Planta medica 2005;71(9):867-70.
2005: Chin-Chung Wu; Mei-Ling Chan; Wen-Ying Chen; Ching-Yi Tsai; Fang-Rong Chang; Yang-Chang Wu
Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria.
Molecular cancer therapeutics 2005;4(8):1277-85.
2005: Chih-Chuang Liaw; Fang-Rong Chang; Shu-Li Chen; Chin-Chung Wu; Kuo-Hsiung Lee; Yang-Chang Wu
Novel cytotoxic monotetrahydrofuranic Annonaceous acetogenins from Annona montana.
Bioorganic & medicinal chemistry 2005;13(15):4767-76.
2005: Hsia-Fen Hsu; Jer-Yiing Houng; Chao-Lin Chang; Chin-Chung Wu; Fang-Rong Chang; Yang-Chang Wu
Antioxidant activity, cytotoxicity, and DNA information of Glossogyne tenuifolia.
Journal of agricultural and food chemistry 2005;53(15):6117-25.
2005: Fang-Rong Chang; Yang-Chang Wu
New bisbenzylisoquinolines, fatty acid amidic aporphines, and a protoberberine from Formosan Cocculus orbiculatus.
Journal of natural products 2005;68(7):1056-60.
2005: Fang-Rong Chang; Ken-ichiro Hayashi; Nam-Hai Chua; Shuichi Kamio; Zih-You Huang; Hiroshi Nozaki; Yang-Chang Wu
The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists.
Journal of natural products 2005;68(7):971-3.
2005: Yueh-Hsiung Kuo; Hui-Chi Huang; Li-Ming Yang Kuo; Ya-Wen Hsu; Kuo-Hsiung Lee; Fang-Rong Chang; Yang-Chang Wu
New dammarane-type saponins from the galls of Sapindus mukorossi.
Journal of agricultural and food chemistry 2005;53(12):4722-7.
2005: Pei-Wen Hsieh; Tsann-Long Hwang; Chin-Chung Wu; Fang-Rong Chang; Tsai-Wei Wang; Yang-Chang Wu
The evaluation of 2,8-disubstituted benzoxazinone derivatives as anti-inflammatory and anti-platelet aggregation agents.
Bioorganic & medicinal chemistry letters 2005;15(11):2786-9.
2005: Keh-Shaw Chen; Pei-Wen Hsieh; Tsann-Long Hwang; Fang-Rong Chang; Yang-Chang Wu
Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.
Natural product research 2005;19(3):283-6.
2005: Yang-Chang Wu; Fang-Rong Chang; Chung-Yi Chen
Tryptamine-derived amides and alkaloids from the seeds of Annona atemoya.
Journal of natural products 2005;68(3):406-8.
2005: Pei-Wen Hsieh; Fang-Rong Chang; Ching-Chung Wu; Chien-Ming Li; Kuen-Yuh Wu; Su-Li Chen; Hsin-Fu Yen; Yang-Chang Wu
Longicalycinin A, a new cytotoxic cyclic peptide from Dianthus superbus var. longicalycinus (MAXIM.) WILL.
Chemical & pharmaceutical bulletin 2005;53(3):336-8.
2005: Yu-Hsuan Lan; Fang-Rong Chang; Chih-Chuang Liaw; Chin-Chung Wu; Michael-Y Chiang; Yang-Chang Wu
Digoniodiol, deoxygoniopypyrone A, and goniofupyrone A: three new styryllactones from Goniothalamus amuyon.
Planta medica 2005;71(2):153-9.
2004: Chih-Chuang Liaw; Fang-Rong Chang; Yang-Chang Wu; Hui-Kang Wang; Yuka Nakanishi; Kenneth F Bastow; Kuo-Hsiung Lee
Montacin and cis-montacin, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona montana.
Journal of natural products 2004;67(11):1804-8.
2004: Chih-Chuang Liaw; Fang-Rong Chang; Chin-Chung Wu; Shu-Li Chen; Kenneth F Bastow; Ken-ichiro Hayashi; Hiroshi Nozaki; Kuo-Hsiung Lee; Yang-Chang Wu
Nine new cytotoxic monotetrahydrofuranic Annonaceous acetogenins from Annona montana.
Planta medica 2004;70(10):948-59.
2004: Pei-Wen Hsieh; Fang-Rong Chang; Cheng-Hsien Chang; Pei-Wen Cheng; Lien-Chai Chiang; Fu-Long Zeng; Kuei-Hsiang Lin; Yang-Chang Wu
2-Substituted benzoxazinone analogues as anti-human coronavirus (anti-HCoV) and ICAM-1 expression inhibition agents.
Bioorganic & medicinal chemistry letters 2004;14(18):4751-4.
2004: Pei-Wen Hsieh; Fang-Rong Chang; Ching-Chung Wu; Kuen-Yuh Wu; Chien-Ming Li; Su-Li Chen; Yang-Chang Wu
New cytotoxic cyclic peptides and dianthramide from Dianthus superbus.
Journal of natural products 2004;67(9):1522-7.
2004: Hui-Chiu Chang; Fang-Rong Chang; Yang-Chang Wu; Yung-Hsiung Lai
Anti-cancer effect of liriodenine on human lung cancer cells.
The Kaohsiung journal of medical sciences 2004;20(8):365-71.
2004: Pei-Wen Hsieh; Fang-Rong Chang; Kuo-Hsiung Lee; Tsann-Long Hwang; Sue-Ming Chang; Yang-Chang Wu
A new anti-HIV alkaloid, drymaritin, and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra.
Journal of natural products 2004;67(7):1175-7.
2004: Kenichiro Hayashi; Fang-Rong Chang; Yuka Nakanishi; Kenneth F Bastow; Gordon Cragg; Andrew T McPhail; Hiroshi Nozaki; Kuo-Hsiung Lee
Antitumor agents. 233. Lantalucratins A-F, new cytotoxic naphthoquinones from Lantana involucrata.
Journal of natural products 2004;67(6):990-3.
2004: Yu-Liang Yang; Fang-Rong Chang; Tsann-Long Hwang; Wen-Te Chang; Yang-Chang Wu
Inhibitory effects of ent-kauranes from the stems of Annona squamosa on superoxide anion generation by human neutrophils.
Planta medica 2004;70(3):256-8.
2004: Chin-Chung Wu; Wei-Ya Wang; Reen-Yen Kuo; Fang-Rong Chang; Yang-Chang Wu
Antiplatelet effects of KW-7, a new inhibitor of cyclic nucleotide phosphodiesterases.
European journal of pharmacology 2004;483(2-3):187-94.
2003: Pei-Wen Hsieh; Fang-Rong Chang; Andrew T McPhail; Kuo-Hsiung Lee; Yang-Chang Wu
New cembranolide analogues from the formosan soft coral Sinularia flexibilis and their cytotoxicity.
Natural product research 2003;17(6):409-18.
2003: Fang-Rong Chang; Kenichiro Hayashi; I-Hsiao Chen; Chih-Chuang Liaw; Kenneth F Bastow; Yuka Nakanishi; Hiroshi Nozaki; Gordon Cragg; Yang-Chang Wu; Kuo-Hsiung Lee
Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii.
Journal of natural products 2003;66(11):1416-20.
2003: Fang-Rong Chang; Yue-Han Lee; Yu-Liang Yang; Pei-Wen Hsieh; Ashraf Taha Khalil; Chung-Yi Chen; Yang-Chang Wu
Secoiridoid glycoside and alkaloid constituents of Hydrangea chinensis.
Journal of natural products 2003;66(9):1245-8.
2003: Reen-Yen Kuo; Fang-Rong Chang; Chin-Chun Wu; Ramesh Patnam; Wei-Ya Wang; Ying-Chi Du; Yang-Chang Wu
Antiplatelet activity of benzylisoquinoline derivatives oxidized by cerium(IV) ammonium nitrate.
Bioorganic & medicinal chemistry letters 2003;13(16):2789-93.
2003: Hui-Chi Huang; Sin-Chung Liao; Fang-Rong Chang; Yueh-Hsiung Kuo; Yang-Chang Wu
Molluscicidal saponins from Sapindus mukorossi, inhibitory agents of golden apple snails, Pomacea canaliculata.
Journal of agricultural and food chemistry 2003;51(17):4916-9.
2003: Yuka Nakanishi; Fang-Rong Chang; Chih-Chuang Liaw; Yang-Chang Wu; Kenneth F Bastow; Kuo-Hsiung Lee
Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line.
Journal of medicinal chemistry 2003;46(15):3185-8.
2003: Jiu-Hong Wu; Fang-Rong Chang; Kenichiro Hayashi; Hiroaki Shiraki; Chih-Chuang Liaw; Yuka Nakanishi; Kenneth F Bastow; Donglei Yu; Ih-Sheng Chen; Kuo-Hsiung Lee
Antitumor agents. Part 218: Cappamensin A, a new In vitro anticancer principle, from Capparis sikkimensis.
Bioorganic & medicinal chemistry letters 2003;13(13):2223-5.
2003: Yuh-Chwen Chang; Fang-Rong Chang; Ashraf Taha Khalil; Pei-Wen Hsieh; Yang-Chang Wu
Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana.
Zeitschrift für Naturforschung. C, Journal of biosciences 2003;58(7-8):521-6.
2003: Fang-Rong Chang; Chin-Chung Wu; Tsann-Long Hwang; Ramesh Patnam; Reen-Yen Kuo; Wei-Ya Wang; Yu-Hsuan Lan; Yang-Chang Wu
Effect of active synthetic 2-substituted quinazolinones on anti-platelet aggregation and the inhibition of superoxide anion generation by neutrophils.
Archives of pharmacal research 2003;26(7):511-5.
2003: Keh-Shaw Chen; Chin-Chuang Wu; Fang-Rong Chang; Yi-Chen Chia; Michael-Y Chiang; Wei-Ya Wang; Yang-Chang Wu
Bioactive coumarins from the leaves of Murraya omphalocarpa.
Planta medica 2003;69(7):654-7.
2003: Yu-Hsuan Lan; Fang-Rong Chang; Jin-Hsien Yu; Yu-Liang Yang; Yi-Ling Chang; Shiow-Ju Lee; Yang-Chang Wu
Cytotoxic styrylpyrones from Goniothalamus amuyon.
Journal of natural products 2003;66(4):487-90.
2003: Wen-Li Lo; Chin-Chung Wu; Fang-Rong Chang; Wei-Ya Wang; Ashraf Taha Khalil; Kuo-Hsiung Lee; Yang-Chang Wu
Antiplatelet and anti-HIV constituents from Euchresta formosana.
Natural product research 2003;17(2):91-7.
2003: Reen-Yen Kuo; Chin-Chung Wu; Fang-Rong Chang; Jwu-Lai Yeh; Ing-Jun Chen; Yang-Chang Wu
Antiplatelet activity of synthetic pyrrolo-benzylisoquinolines.
Bioorganic & medicinal chemistry letters 2003;13(5):821-3.
2003: Fang-Rong Chang; Chih-Chuang Liaw; Chih-Yuan Lin; Chi-Jung Chou; Hui-Fen Chiu; Yang-Chang Wu
New adjacent Bis-tetrahydrofuran Annonaceous acetogenins from Annona muricata.
Planta medica 2003;69(3):241-6.
2003: Yuh-Chwen Chang; Pei-Wen Hsieh; Fang-Rong Chang; Ru-Rong Wu; Chih-Chuang Liaw; Kuo-Hsiung Lee; Yang-Chang Wu
Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana.
Planta medica 2003;69(2):148-52.
2003: Chih-Chuang Liaw; Fang-Rong Chang; Ming-Jung Wu; Yang-Chang Wu
A novel constituent from Rollinia mucosa, rollicosin, and a new approach to develop annonaceous acetogenins as potential antitumor agents.
Journal of natural products 2003;66(2):279-81.
2003: Wen-Bin Pan; Fang-Rong Chang; Li-Mei Wei; Yang-Chang Wu
New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity.
Journal of natural products 2003;66(2):161-8.
2003: Sheng-Nan Wu; Hung-Ting Chiang; Fang-Rong Chang; Chih-Chuang Liaw; Yang-Chang Wu
Stimulatory effects of squamocin, an Annonaceous acetogenin, on Ca(2+)-activated K+ current in cultured smooth muscle cells of human coronary artery.
Chemical research in toxicology 2003;16(1):15-22.
2003: Ashraf Taha Khalil; Fang-Rong Chang; Yue-Han Lee; Chung-Yi Chen; Chih-Chuang Liaw; Patnam Ramesh; Shyng-Shiou F Yuan; Yang-Chang Wu
Chemical constituents from the Hydrangea chinensis.
Archives of pharmacal research 2003;26(1):15-20.
2002: Yu-Liang Yang; Fang-Rong Chang; Chin-Chung Wu; Wei-Ya Wang; Yang-Chang Wu
New ent-kaurane diterpenoids with anti-platelet aggregation activity from Annona squamosa.
Journal of natural products 2002;65(10):1462-7.
2002: Wen-Li Lo; Fang-Rong Chang; Tian-Jye Hsieh; Yang-Chang Wu
Coumaronochromones and flavanones from Euchresta formosana roots.
Phytochemistry 2002;60(8):839-45.
2002: Chih-Chuang Liaw; Fang-Rong Chang; Chih-Yuan Lin; Chi-Jung Chou; Hui-Fen Chiu; Ming-Jung Wu; Yang-Chang Wu
New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata.
Journal of natural products 2002;65(4):470-5.
2002: Fang-Rong Chang; Tian-Jye Hsieh; Ti-Lung Huang; Chung-Yi Chen; Reen-Yen Kuo; Yuh-Chwen Chang; Hui-Fen Chiu; Yang-Chang Wu
Cytotoxic constituents of the stem bark of Neolitsea acuminatissima.
Journal of natural products 2002;65(3):255-8.
2002: Wen-Li Lo; Fang-Rong Chang; Chih-Chuang Liaw; Yang-Chang Wu
Cytotoxic coumaronochromones from the roots of Euchresta formosana.
Planta medica 2002;68(2):146-51.
2001: J Ito; Fang-Rong Chang; Hui-Kang Wang; Y K Park; M Ikegaki; Nicole Kilgore; Kuo-Hsiung Lee
Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis.
Journal of natural products 2001;64(10):1278-81.
2001: Tian-Jye Hsieh; Fang-Rong Chang; YC Chia; Chung-Yi Chen; Hang-Ching Lin; Hui-Fen Chiu; Yang-Chang Wu
The alkaloids of Artabotrys uncinatus.
Journal of natural products 2001;64(9):1157-61.
2001: Ramesh Patnam; Fang-Rong Chang; Chung-Yi Chen; Reen-Yen Kuo; Yue-Han Lee; Yang-Chang Wu
Hydrachine A, a novel alkaloid from the roots of Hydrangea chinensis.
Journal of natural products 2001;64(7):948-9.
2001: Fang-Rong Chang; Yang-Chang Wu
Novel cytotoxic annonaceous acetogenins from Annona muricata.
Journal of natural products 2001;64(7):925-31.
2001: Reen-Yen Kuo; Fang-Rong Chang; Chung-Yi Chen; Che-Ming Teng; Hsin-Fu Yen; Yang-Chang Wu
Antiplatelet activity of N-methoxycarbonyl aporphines from Rollinia mucosa.
Phytochemistry 2001;57(3):421-5.
2001: Tian-Jye Hsieh; Fang-Rong Chang; YC Chia; Chung-Yi Chen; Hui-Fen Chiu; Yang-Chang Wu
Cytotoxic constituents of the fruits of Cananga odorata.
Journal of natural products 2001;64(5):616-9.
2001: Chung-Yi Chen; Fang-Rong Chang; Wen-Bin Pan; Yang-Chang Wu
Four alkaloids from Annona cherimola.
Phytochemistry 2001;56(7):753-7.
2000: Z Xu; Fang-Rong Chang; Hui-Kang Wang; Yoshiki Kashiwada; Andrew T McPhail; Kenneth F Bastow; Y Tachibana; M Cosentino; Kuo-Hsiung Lee
Anti-HIV agents 45(1) and antitumor agents 205.(2) two new sesquiterpenes, leitneridanins A and B, and the cytotoxic and anti-HIV principles from Leitneria floridana.
Journal of natural products 2000;63(12):1712-5.
2000: Chung-Yi Chen; Fang-Rong Chang; Y C Shih; Tian-Jye Hsieh; YC Chia; Huan-Yi Tseng; H C Chen; S J Chen; Ming-Chu Hsu; Yang-Chang Wu
Cytotoxic constituents of Polyalthia longifolia var. pendula.
Journal of natural products 2000;63(11):1475-8.
2000: Wen-Bin Pan; Fang-Rong Chang; Yang-Chang Wu
Spirostanol sapogenins from the underground parts of Tupistra chinensis.
Chemical & pharmaceutical bulletin 2000;48(9):1350-3.
2000: Y C Chia; Fang-Rong Chang; C M Teng; Yang-Chang Wu
Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii.
Journal of natural products 2000;63(8):1160-3.
2000: Chung-Yi Chen; Fang-Rong Chang; C P Cho; Yang-Chang Wu
ent-kaurane diterpenoids from Annona glabra.
Journal of natural products 2000;63(7):1000-3.
2000: Wen-Bin Pan; Fang-Rong Chang; Yang-Chang Wu
Tupichigenin A, a new steroidal sapogenin from Tupistra chinensis.
Journal of natural products 2000;63(6):861-3.
2000: Fang-Rong Chang; Chung-Yi Chen; P H Wu; Reen-Yen Kuo; Yuh-Chwen Chang; Yang-Chang Wu
New alkaloids from Annona purpurea.
Journal of natural products 2000;63(6):746-8.
1999: Chih-Chuang Liaw; Fang-Rong Chang; Y Y Chen; Hui-Fen Chiu; Ming-Jung Wu; Yang-Chang Wu
New annonaceous acetogenins from Rollinia mucosa.
Journal of natural products 1999;62(12):1613-7.
1999: Chung-Yi Chen; Fang-Rong Chang; Hui-Fen Chiu; Ming-Jung Wu; Yang-Chang Wu
Aromin-A, an Annonaceous acetogenin from Annona cherimola.
Phytochemistry 1999;51(3):429-33.
1998: Fang-Rong Chang; J L Wei; Che-Ming Teng; Yang-Chang Wu
Two new 7-dehydroaporphine alkaloids and antiplatelet action aporphines from the leaves of Annona purpurea.
Phytochemistry 1998;49(7):2015-8.
1998: Fang-Rong Chang; J L Wei; Che-Ming Teng; Yang-Chang Wu
Antiplatelet aggregation constituents from Annona purpurea.
Journal of natural products 1998;61(12):1457-61.
1998: Fang-Rong Chang; Y C Chao; Che-Ming Teng; Yang-Chang Wu
Chemical constituents from Cassytha filiformis II.
Journal of natural products 1998;61(7):863-6.
1998: Fang-Rong Chang; J L Chen; Hui-Fen Chiu; Ming-Jung Wu; Yang-Chang Wu
Acetogenins from seeds of Annona reticulata.
Phytochemistry 1998;47(6):1057-61.
1996: Yang-Chang Wu; Y C Hung; Fang-Rong Chang; M Cosentino; H K Wang; Kuo-Hsiung Lee
Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.
Journal of natural products 1996;59(6):635-7.