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Thomas Ming Swi Chang

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Living Beings

Objects

Artificial Membranes

Procedures

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Artificial Organs

Anatomy

Liver

Occupations

Biotechnology

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Co-Publications
Name
8
Prakash, Satya
7
Yu, WP
6
Yu, Binglan
6
D'Agnillo, F
5
Liu, Zun Chang
4
Sipehia, R
3
Wong, JP
3
Mobed, M
2
Orive, Gorka
2
Pedraz, José Luis
2
de Vos, Paul
2
Calafiore, Riccardo
2
Chow, Kai Ming
2
Hernández, Rosa
2
Hunkeler, David

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Publications

TOP 3
Gu Jingsong; Chang Thomas Ming Swi
Extraction of erythrocyte enzymes for the preparation of polyhemoglobin-catalase-superoxide dismutase.
Stefanescu Ada; Chang Thomas Ming Swi
Use of the labscale tangential flow diafiltrator to remove tetrameric hemoglobin from polyhemoglobin, purify hemolysate, and concentrate polyhemoglobin.
Chang Thomas Ming Swi
Nanobiotechnological modification of hemoglobin and enzymes from this laboratory.

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All Publications

2009: Gu Jingsong; Chang Thomas Ming Swi
Extraction of erythrocyte enzymes for the preparation of polyhemoglobin-catalase-superoxide dismutase.
Artificial cells, blood substitutes, and immobilization biotechnology 2009;37(2):69-77.
2009: Stefanescu Ada; Chang Thomas Ming Swi
Use of the labscale tangential flow diafiltrator to remove tetrameric hemoglobin from polyhemoglobin, purify hemolysate, and concentrate polyhemoglobin.
Artificial cells, blood substitutes, and immobilization biotechnology 2009;37(2):61-8.
2008: Chang Thomas Ming Swi
Nanobiotechnological modification of hemoglobin and enzymes from this laboratory.
Biochimica et biophysica acta 2008;1784(10):1435-40.
2008: Chang Thomas Ming Swi
Safety of red blood cell substitutes as compared to stored donor red blood cells.
Artificial cells, blood substitutes, and immobilization biotechnology 2008;36(1):1-2.
2007: Chang Thomas Ming Swi
50th anniversary of artificial cells: their role in biotechnology, nanomedicine, regenerative medicine, blood substitutes, bioencapsulation, cell/stem cell therapy and nanorobotics.
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(6):545-54.
2007: Wong Naomi S W; Chang Thomas M S
Polyhemoglobin-fibrinogen: a novel oxygen carrier with platelet-like properties in a hemodiluted setting.
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(5):481-9.
2006: Chang Thomas Ming Swi
Blood substitutes based on nanobiotechnology.
Trends in biotechnology 2006;24(8):372-7.
2006: Liu Zun Chang; Chang Thomas Ming Swi
Transdifferentiation of bioencapsulated bone marrow cells into hepatocyte-like cells in the 90% hepatectomized rat model.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(4):566-72.
2006: Chang Thomas Ming Swi
Evolution of artificial cells using nanobiotechnology of hemoglobin based RBC blood substitute as an example.
Artificial cells, blood substitutes, and immobilization biotechnology 2006;34(6):551-66.
2006: Chang Liu Zun; Chang Thomas Ming Swi
Coencapsulation of hepatocytes and bone marrow cells: in vitro and in vivo studies.
Biotechnology annual review 2006;12():137-51.
2006: Yu Binglan; Liu Zunchang; Chang Thomas Ming Swi
Polyhemoglobin with different percentage of tetrameric hemoglobin and effects on vasoactivity and electrocardiogram.
Artificial cells, blood substitutes, and immobilization biotechnology 2006;34(2):159-73.
2005: Chang T M S
The role of artificial cells in cell and organ transplantation in regenerative medicine.
Panminerva medica 2005;47(1):1-9.
2005: Chang Thomas Ming Swi
Therapeutic applications of polymeric artificial cells.
Nature reviews. Drug discovery 2005;4(3):221-35.
2005: Liu Zun Chang; Chang Thomas Ming Swi
Transplantation of bioencapsulated bone marrow stem cells improves hepatic regeneration and survival of 90% hepatectomized rats: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 2005;33(4):405-10.
2004: Chang Thomas Ming Swi
Hemoglobin-based red blood cell substitutes.
Artificial organs 2004;28(9):789-94.
2004: Yu B; Chang T M S
In vitro and in vivo enzyme studies of polyhemoglobin-tyrosinase.
Biotechnology and bioengineering 2004;86(7):835-41.
2004: Yu Binglan; Chang Thomas Ming Swi
Polyhemoglobin-tyrosinase, an oxygen carrier with murine B16F10 melanoma suppression properties: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 2004;32(2):293-302.
2004: Yu Binglan; Chang Thomas Ming Swi
Effects of long-term oral administration of polymeric microcapsules containing tyrosinase on maintaining decreased systemic tyrosine levels in rats.
Journal of pharmaceutical sciences 2004;93(4):831-7.
2004: Chang Thomas Ming Swi
Artificial cells for cell and organ replacements.
Artificial organs 2004;28(3):265-70.
2004: Yu Binglan; Chang Thomas Ming Swi
Effects of combined oral administration and intravenous injection on maintaining decreased systemic tyrosine levels in rats.
Artificial cells, blood substitutes, and immobilization biotechnology 2004;32(1):129-48.
2004: Chang Thomas Ming Swi
Artificial cell bioencapsulation in macro, micro, nano, and molecular dimensions: keynote lecture.
Artificial cells, blood substitutes, and immobilization biotechnology 2004;32(1):1-23.
2004: Chang Thomas Ming Swi
A new red blood cell substitute.
Critical care medicine 2004;32(2):612-3.
2004: Orive Gorka; Hernández Rose Maria; Rodríguez Gascón Alicia; Calafiore Riccardo; Chang Thomas Ming Swi; de Vos Paul; Hortelano Gonzalo; Hunkeler David; Lacík Igor; Pedraz José Luis
History, challenges and perspectives of cell microencapsulation.
Trends in biotechnology 2004;22(2):87-92.
2003: Chow Kai Ming; Liu Zun Chang; Prakash Satya; Chang Thomas M S
Free and microencapsulated Lactobacillus and effects of metabolic induction on urea removal.
Artificial cells, blood substitutes, and immobilization biotechnology 2003;31(4):425-34.
2003: Liu Zun Chang; Chow Kai Ming; Chang Thomas Ming-Swi
Evaluation of two protocols of uremic rat model: partial nephrectomy and infarction.
Renal failure 2003;25(6):935-43.
2003: Chang Thomas M S; Powanda Douglas; Yu W P
Analysis of polyethylene-glycol-polylactide nano-dimension artificial red blood cells in maintaining systemic hemoglobin levels and prevention of methemoglobin formation.
Artificial cells, blood substitutes, and immobilization biotechnology 2003;31(3):231-47.
2003: Liu Z C; Chang T M S
Coencapsulation of hepatocytes and bone marrow stem cells: in vitro conversion of ammonia and in vivo lowering of bilirubin in hyperbilirubemia Gunn rats.
The International journal of artificial organs 2003;26(6):491-7.
2003: Chang Thomas Ming Swi
Artificial cells for replacement of metabolic organ functions.
Artificial cells, blood substitutes, and immobilization biotechnology 2003;31(2):151-61.
2003: Chang T M S
Future generations of red blood cell substitutes.
Journal of internal medicine 2003;253(5):527-35.
2003: Orive Gorka; Hernández Rosa María; Gascón Alicia R; Calafiore Riccardo; Chang Thomas M S; De Vos Paul; Hortelano Gonzalo; Hunkeler David; Lacík Igor; Shapiro A M James; Pedraz José Luis
Cell encapsulation: promise and progress.
Nature medicine 2003;9(1):104-7.
2002: Yu Binglan; Chang Thomas Ming Swi
In vitro enzyme kinetics of microencapsulated tyrosinase.
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):533-46.
2002: Chang Thomas Ming Swi
Artificial cells. General discussions and perspectives. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):499-501.
2002: Chang Thomas Ming Swi
Artificial cells for artificial organs. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):469-97.
2002: Chang Thomas Ming Swi
Artificial cells containing detoxicants. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):457-68.
2002: Chang Thomas Ming Swi
Artificial cells perfused by body fluids. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):439-56.
2002: Chang Thomas Ming Swi
Red blood cell substitutes. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):421-37.
2002: Chang Thomas Ming Swi
Experimental enzyme therapy. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):407-19.
2002: Chang Thomas Ming Swi
Biological activity of artificial cells. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):397-406.
2002: Chang Thomas Ming Swi
Artificial cells. Biophysical properties. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):375-96.
2002: Chang Thomas Ming Swi
Artificial cells. Preparation. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):349-73.
2002: Chang Thomas Ming Swi
Artificial cells. General consideration. 1972 [classical article]
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(5-6):339-48.
2002: Chang Thomas M S
Oxygen carriers.
Current opinion in investigational drugs (London, England : 2000) 2002;3(8):1187-90.
2002: Liu Zun Chang; Chang Thomas Ming Swi
Increased viability of transplanted hepatocytes when hepatocytes are co-encapsulated with bone marrow stem cells using a novel method.
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(2):99-112.
2002: Powanda D Douglas; Chang Thomas M S
Cross-linked polyhemoglobin-superoxide dismutase-catalase supplies oxygen without causing blood-brain barrier disruption or brain edema in a rat model of transient global brain ischemia-reperfusion.
Artificial cells, blood substitutes, and immobilization biotechnology 2002;30(1):23-37.
2001: Chang T M
Present status of modified hemoglobin as blood substitutes and oral therapy for end stage renal failure using artificial cells containing genetically engineered cells.
Annals of the New York Academy of Sciences 2001;944():362-72.
2000: Chang T M
Red blood cell substitutes.
Baillière's best practice & research. Clinical haematology 2000;13(4):651-67.
2000: Prakash S; Chang T M
Artificial cells microencapsulated genetically engineered E. coli DH5 cells for the lowering of plasma creatinine in-vitro and in-vivo.
Artificial cells, blood substitutes, and immobilization biotechnology 2000;28(5):397-408.
2000: Prakash S; Chang T M
In vitro and in vivo uric acid lowering by artificial cells containing microencapsulated genetically engineered E. coli DH5 cells.
The International journal of artificial organs 2000;23(7):429-35.
2000: Liu Z; Chang T M
Effects of bone marrow cells on hepatocytes: when co-cultured or co-encapsulated together.
Artificial cells, blood substitutes, and immobilization biotechnology 2000;28(4):365-74.
2000: Chang T M; D'Agnillo F; Yu W P; Razack S
Two future generations of blood substitutes based on polyhemoglobin-SOD-catalase and nanoencapsulation.
Advanced drug delivery reviews 2000;40(3):213-8.
2000: Yu W P; Wong J P; Chang T M
Sustained drug release characteristics of biodegradable composite poly(d,l)lactic acid-poly(l)lactic acid microcapsules containing ciprofloxacin.
Artificial cells, blood substitutes, and immobilization biotechnology 2000;28(1):39-55.
2000: Chang T M
Artificial cell biotechnology for medical applications.
Blood purification 2000;18(2):91-6.
1999: Prakash S; Chang T M
Artificial cell microcapsules containing genetically engineered E. coli DH5 cells for in-vitro lowering of plasma potassium, phosphate, magnesium, sodium, chloride, uric acid, cholesterol, and creatinine: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 1999;27(5-6):475-81.
1999: Bruni S; Chang T M
Comparison of bilirubin conjugation in encapsulated hepatocytes, hepatocyte homogenate and intact hepatocytes.
Artificial cells, blood substitutes, and immobilization biotechnology 1999;27(4):357-65.
1999: Bruni S; Chang T M
Kinetic studies of hepatocyte UDP-glucuronosyltransferase: evidence of an allosteric enzyme.
Artificial cells, blood substitutes, and immobilization biotechnology 1999;27(4):343-56.
1999: Chang T M
Artificial cells, encapsulation, and immobilization.
Annals of the New York Academy of Sciences 1999;875():71-83.
1999: Prakash S; Chang T M
Growth kinetics of genetically engineered E. coli DH 5 cells in artificial cell APA membrane microcapsules: preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 1999;27(3):291-301.
1999: Yu W P; Wong J P; Chang T M
Biodegradable polylactic acid nanocapsules containing ciprofloxacin: preparation and characterization.
Artificial cells, blood substitutes, and immobilization biotechnology 1999;27(3):263-78.
1999: Chang T M
Future prospects for artificial blood.
Trends in biotechnology 1999;17(2):61-7.
1998: Chang T M
Artificial cells with emphasis on cell encapsulation of genetically engineered cells.
Artificial organs 1998;22(11):958-65.
1998: Mobed M; Chang T M
Adsorption of chitin derivatives onto liposomes: optimization of adsorption conditions.
Journal of microencapsulation 1998;15(5):595-607.
1998: Mobed M; Chang T M
Comparison of polymerically stabilized PEG-grafted liposomes and physically adsorbed carboxymethylchitin and carboxymethyl/glycolchitin liposomes for biological applications.
Biomaterials 1998;19(13):1167-77.
1998: D'Agnillo F; Chang T M
Polyhemoglobin-superoxide dismutase-catalase as a blood substitute with antioxidant properties.
Nature biotechnology 1998;16(7):667-71.
1998: Yu W P; Wong J P; Chang T M
Preparation of polylactic acid microcapsules containing ciprofloxacin.
Journal of microencapsulation 1998;15(4):515-23.
1998: D'Agnillo F; Chang T M
Absence of hemoprotein-associated free radical events following oxidant challenge of crosslinked hemoglobin-superoxide dismutase catalase.
Free radical biology & medicine 1998;24(6):906-12.
1998: Chang T M
Pharmaceutical and therapeutic applications of artificial cells including microencapsulation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;45(1):3-8.
1998: Prakash S; Chang T M
Growth and survival of renal failure rats that received oral microencapsulated genetically engineered E. coli DH5 cells for urea removal.
Artificial cells, blood substitutes, and immobilization biotechnology 1998;26(1):35-51.
1998: Chang T M
Modified hemoglobin blood substitutes: present status and future perspectives.
Biotechnology annual review 1998;4():75-112.
1998: Chang T M
Modified hemoglobin-based blood substitutes: crosslinked, recombinant and encapsulated hemoglobin.
Vox sanguinis 1998;74 Suppl 2():233-41.
1997: Chang T M
Artificial cells and bioencapsulation in bioartificial organs.
Annals of the New York Academy of Sciences 1997;831():249-59.
1997: Mobed M; Chang T M
Kinetic aspects of polyelectrolyte adsorption: adsorption of chitin derivatives onto liposomes as a model system.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(4):367-77.
1997: Razack S; D'Agnillo F; Chang T M
Crosslinked hemoglobin-superoxide dismutase-catalase scavenges free radicals in a rat model of intestinal ischemia-reperfusion injury.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):181-92.
1997: D'Agnillo F; Chang T M
Reduction of hydroxyl radical generation in a rat hindlimb model of ischemia-reperfusion injury using crosslinked hemoglobin-superoxide dismutase-catalase.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):163-80.
1997: Chang T M
Recent and future developments in modified hemoglobin and microencapsulated hemoglobin as red blood cell substitutes.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):1-24.
1997: Chang T M; Prakash S
Artificial cells for bioencapsulation of cells and genetically engineered E. coli. For cell therapy, gene therapy, and removal of urea and ammonia.
Methods in molecular biology (Clifton, N.J.) 1997;63():343-58.
1996: Prakash S; Chang T M
Microencapsulated genetically engineered live E. coli DH5 cells administered orally to maintain normal plasma urea level in uremic rats.
Nature medicine 1996;2(8):883-7.
1996: Prakash S; Chang T M
Microencapsulated genetically engineered E. coli DH5 cells for plasma urea and ammonia removal based on: 1. Column bioreactor and 2. Oral administration in uremic rats.
Artificial cells, blood substitutes, and immobilization biotechnology 1996;24(3):201-18.
1996: Yu W P; Chang T M
Submicron polymer membrane hemoglobin nanocapsules as potential blood substitutes: preparation and characterization.
Artificial cells, blood substitutes, and immobilization biotechnology 1996;24(3):169-83.
1996: Mobed M; Eng M; Chang T M
The importance of standardization of carboxymethylchitin concentration by the dye-binding capacity of alcian blue before adsorption on liposomes.
Artificial cells, blood substitutes, and immobilization biotechnology 1996;24(2):107-20.
1995: Bruni S; Chang T M
Effect of donor strains and age of the recipient in the use of microencapsulated hepatocytes to control hyperbilirubinemia in the Gunn rat.
The International journal of artificial organs 1995;18(6):332-9.
1995: Bruni S; Chang T M
Kinetic analysis of UDP-glucuronosyltransferase in bilirubin conjugation by encapsulated hepatocytes for transplantation into Gunn rats.
Artificial organs 1995;19(5):449-57.
1995: Chang T M
Artificial cells with emphasis on bioencapsulation in biotechnology.
Biotechnology annual review 1995;1():267-95.
1995: Quebec E A; Chang T M
Superoxide dismutase and catalase cross-linked to polyhemoglobin reduces methemoglobin formation in vitro.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(6):693-705.
1995: Safos S; Chang T M
Enzyme replacement therapy in ENU2 phenylketonuric mice using oral microencapsulated phenylalanine ammonia-lyase: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(6):681-92.
1995: Chang T M; Bourget L; Lister C
A new theory of enterorecirculation of amino acids and its use for depleting unwanted amino acids using oral enzyme-artificial cells, as in removing phenylalanine in phenylketonuria.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(1):1-21.
1995: Chang T M
Cross-linked hemoglobins being well into clinical trials, increasing research efforts are now on a second generation red blood cell substitute based on encapsulated hemoglobin.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(3):257-62.
1994: Chang T M; Lister C W
Assessment of blood substitutes: II. In-vitro complement activation of human plasma and blood for safety studies in research, development, industrial production and preclinical analysis.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(2):171-80.
1994: Chang T M; Varma R
Assessment of blood substitutes: I. Efficacy studies in anesthetized and conscious rats with loss of 1/3, 1/2 and 2/3 blood volume.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(2):159-69.
1994: Yu W P; Chang T M
Submicron biodegradable polymer membrane hemoglobin nanocapsules as potential blood substitutes: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):889-93.
1994: Nishiya T; Chang T M
Toxicity of liposomes containing low mol% of dienoyl phosphocholine to blood: use of carboxymethyl chitin to reduce toxicity.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):883-8.
1994: Ilan E; Chang T M
Human hemoglobin anaerobically reacted with divinyl sulfone: a source for oxygen carriers.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):687-93.
1993: Koo J; Chang T M
Secretion of erythropoietin from microencapsulated rat kidney cells: preliminary results.
The International journal of artificial organs 1993;16(7):557-60.
1993: Ilan E; Morton P G; Chang T M
The anaerobic reaction of bovine hemoglobin with divinyl sulfone: structural changes and functional consequences.
Biochimica et biophysica acta 1993;1163(3):257-65.
1993: Chang T M
Safety studies of modified hemoglobin as an oxygen-carrying blood substitute.
Hematologic pathology 1993;7(1):49-55.
1993: Lloyd-George I; Chang T M
Free and microencapsulated Erwinia herbicola for the production of tyrosine.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(3):323-33.
1993: Chang T M
Bioencapsulation in biotechnology.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(3):291-7.
1993: Chang T M
Adequacy of hemoperfusion for blood purification in uremia.
Contributions to nephrology 1993;103():10-25.
1993: Chang T M; Lister C W
Use of finger-prick human blood samples as a more convenient way for in-vitro screening of modified hemoglobin blood substitutes for complement activation: a preliminary report.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(5):685-90.
1993: Prakash S; Chang T M
Genetically engineered E. coli cells containing K. aerogenes gene, microencapsulated in artificial cells for urea and ammonia removal.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(5):629-36.
1993: D'Agnillo F; Chang T M
Cross-linked hemoglobin-superoxide dismutase-catalase scavenges oxygen-derived free radicals and prevents methemoglobin formation and iron release.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(5):609-21.
1993: Coromili V; Chang T M
Polydisperse dextran as a diffusing test solute to study the membrane permeability of alginate polylysine microcapsules.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1993;21(3):427-44.
1992: Ito Y; Chang T M
In vitro study of multicellular hepatocyte spheroids formed in microcapsules.
Artificial organs 1992;16(4):422-7.
1992: Chang T M
Hybrid artificial cells: microencapsulation of living cells.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1992;38(2):128-30.
1992: Chang T M
Artificial cells: 35 years.
Artificial organs 1992;16(1):8-12.
1992: Chang T M
Artificial liver support based on artificial cells with emphasis on encapsulated hepatocytes.
Artificial organs 1992;16(1):71-4.
1992: Mobed M; Nishiya T; Chang T M
Purification and characterization of liposomes encapsulating hemoglobin as potential blood substitutes.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(1):53-70.
1992: Chang T M
Artificial cells in immobilization biotechnology.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(5):1121-43.
1992: Chang T M; Lister C; Nishiya; Varma R
Immunological effects of hemoglobin, encapsulated hemoglobin, polyhemoglobin and conjugated hemoglobin using different immunization schedules.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):611-8.
1992: Chang T M; Lister C
A preclinical screening test for modified hemoglobin to bridge the gap between animal safety studies and use in human.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):565-73.
1992: Chang T M; Varma R
Effect of a single replacement of one of Ringer lactate, hypertonic saline/dextran, 7g% albumin, stroma-free hemoglobin, o-raffinose polyhemoglobin or whole blood on the long term survival of unanesthetized rats with lethal hemorrhagic shock after 67% acute blood loss.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):503-10.
1992: Mobed M; Chang T M
Purification and quantitative determination of carboxymethylchitin incorporation into submicron bilayer-lipid membrane artificial cells (liposomes) encapsulating hemoglobin.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):369-76.
1992: Mobed M; Nishiya T; Chang T M
Preparation of carboxymethylchitin-incorporated submicron bilayer-lipid membrane artificial cells (liposomes) encapsulating hemoglobin.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):365-8.
1992: Ilan E; Morton P G; Chang T M
Bovine hemoglobin anaerobically reacted with divinyl sulfone: a potential source for hypothermic oxygen carriers.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):263-75.
1992: Chang T M
Blood substitutes based on modified hemoglobin prepared by encapsulation or crosslinking: an overview.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):159-79.
1991: Bruni S; Chang T M
Encapsulated hepatocytes for controlling hyperbilirubinemia in Gunn rats.
The International journal of artificial organs 1991;14(4):239-41.
1991: Cattaneo M V; Chang T M
The potential of a microencapsulated urease-zeolite oral sorbent for the removal of urea in uremia.
ASAIO transactions / American Society for Artificial Internal Organs 1991;37(2):80-7.
1991: Garofalo F A; Chang T M
Effects of mass transfer and reaction kinetics on serum cholesterol depletion rates of free and immobilized Pseudomonas pictorum.
Applied biochemistry and biotechnology 1991;27(1):75-91.
1991: Mobed M; Chang T M
Preparation and surface characterization of carboxymethylchitin-incorporated submicron bilayer-lipid membrane artificial cells (liposomes) encapsulating hemoglobin.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1991;19(4):731-44.
1991: Wong H; Chang T M
A novel two step procedure for immobilizing living cells in microcapsules for improving xenograft survival.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1991;19(4):687-97.
1991: Wong H; Chang T M
The microencapsulation of cells within alginate poly-L-lysine microcapsules prepared with the standard single step drop technique: histologically identified membrane imperfections and the associated graft rejection.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1991;19(4):675-86.
1991: Kashani S A; Chang T M
Physicochemical characteristics of hepatic stimulatory factor prepared from cell free supernatant of hepatocyte cultures.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1991;19(3):579-98.
1991: Kashani S A; Chang T M
Effects of hepatic stimulatory factor released from free or microencapsulated hepatocytes on galactosamine induced fulminant hepatic failure animal model.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1991;19(3):565-77.
1991: Chang T M
Therapeutic applications of immobilized proteins and cells.
Bioprocess technology 1991;14():305-18.
1990: Gu K F; Chang T M
Conversion of ammonia or urea into essential amino acids, L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD. L-lactic dehydrogenase for coenzyme recycling.
Applied biochemistry and biotechnology 1990;26(2):115-24.
1990: Ning J; Chang T M
In vivo effects of stroma-free hemoglobin and polyhemoglobin on coagulation factors in rats.
The International journal of artificial organs 1990;13(8):509-16.
1990: Gu K F; Chang T M
Conversion of ammonia or urea into essential amino acids, L-leucine, L-valine, and L-isoleucine, using artificial cells containing an immobilized multienzyme system and dextran-NAD+. 2. Yeast alcohol dehydrogenase for coenzyme recycling.
Biotechnology and applied biochemistry 1990;12(3):227-36.
1990: Khanna R; Chang T M
Characterization of L-histidine ammonia-lyase immobilized by microencapsulation in artificial cells: preparation, kinetics, stability, and in vitro depletion of histidine.
The International journal of artificial organs 1990;13(3):189-95.
1990: Dixit V; Chang T M
Brain edema and the blood brain barrier in galactosamine-induced fulminant hepatic failure rats. An animal model for evaluation of liver support systems.
ASAIO transactions / American Society for Artificial Internal Organs 1990;36(1):21-7.
1990: Walter S V; Chang T M
Chronotropic effects of in vitro perfusion with albumin, stroma-free hemoglobin, and polyhemoglobin solutions.
Biomaterials, artificial cells, and artificial organs 1990;18(2):283-98.
1990: Ning J; Chang T M
Effects of homologous and heterologous stroma-free hemoglobin and polyhemoglobin on complement activation, leucocytes and platelets.
Biomaterials, artificial cells, and artificial organs 1990;18(2):219-32.
1990: Ning J; Chang T M
Whole complement hemolytic activity (CH50) following infusion of stroma-free and polyhemoglobin solutions in rats.
Biomaterials, artificial cells, and artificial organs 1990;18(2):203-17.
1990: Chang T M; Lister C
A screening test for modified hemoglobin blood substitutes before clinical use: based on C3a complement activation in human plasma.
Biomaterials, artificial cells, and artificial organs 1990;18(5):693-701.
1990: Sipehia R; Garfinkle A; Jackson W B; Chang T M
Towards an artificial cornea: surface modifications of optically clear, oxygen permeable soft contact lens materials by ammonia plasma modification technique for the enhanced attachment and growth of corneal epithelial cells.
Biomaterials, artificial cells, and artificial organs 1990;18(5):643-55.
1990: Chang T M
Biotechnological and medical applications based on immobilization of hepatocytes, microorganisms, or enzyme systems by microencapsulation in artificial cells.
Annals of the New York Academy of Sciences 1990;613():109-15.
1989: Chang T M
The use of modified hemoglobin as an oxygen carrying blood substitute.
Transfusion medicine reviews 1989;3(3):213-8.
1989: Daka N J; Sipehia R; Chang T M
Enhanced oxidation of bilirubin by an immobilized tri-enzyme system of glucose oxidase, bilirubin oxidase and horseradish peroxidase.
Biochimica et biophysica acta 1989;991(3):487-9.
1989: Lalla F R; Ning J; Chang T M
Effects of pyridoxalated polyhemoglobin and stroma-free hemoglobin on ADP-induced platelet aggregation.
Biomaterials, artificial cells, and artificial organs 1989;17(3):363-9.
1989: Garofalo F A; Chang T M
Immobilization of P. pictorum in open pore agar, alginate and polylysine-alginate microcapsules for serum cholesterol depletion.
Biomaterials, artificial cells, and artificial organs 1989;17(3):271-89.
1989: Bourget L; Chang T M
Effects of oral administration of artificial cells immobilized phenylalanine ammonia-lyase on intestinal amino acids of phenylketonuric rats.
Biomaterials, artificial cells, and artificial organs 1989;17(2):161-81.
1989: Chang T M; Barre P; Lister C; Kuruvilla S
Artificial cells in medical applications with emphasis on hemoperfusion in aluminium removal and cross-over control clinical trial of reduced time hemoperfusion-hemodialysis.
Contributions to nephrology 1989;70():237-49.
1989: Chang T M
Preparation and characterisation of xanthine oxidase immobilised by microencapsulation in artificial cells for the removal of hypoxanthine.
Biomaterials, artificial cells, and artificial organs 1989;17(5):611-6.
1989: Daka J N; Chang T M
Bilirubin removal by the pseudoperoxidase activity of free and immobilized hemoglobin and hemoglobin co-immobilized with glucose oxidase.
Biomaterials, artificial cells, and artificial organs 1989;17(5):553-62.
1989: Bruni S; Chang T M
Hepatocytes immobilised by microencapsulation in artificial cells: effects on hyperbilirubinemia in Gunn rats.
Biomaterials, artificial cells, and artificial organs 1989;17(4):403-11.
1988: Nishiya T; Okumura Y; Chang T M
Syntheses and properties of circular dichroism active phospholipids.
Chemistry and physics of lipids 1988;49(1-2):69-79.
1988: Nishiya T; DasGupta M; Okumura Y; Chang T M
Circular dichroism study of membrane dynamics focused on effect of monosialogangliosides.
Journal of biochemistry 1988;104(1):62-5.
1988: Chang T M; Langer R; Sparks R E; Reach G
Drug delivery systems in biotechnology.
Artificial organs 1988;12(3):248-51.
1988: Sipehia R; Chawla A S; Daka J; Chang T M
Immobilization of enzymes on polypropylene bead surfaces by anhydrous ammonia gaseous plasma technique.
Journal of biomedical materials research 1988;22(5):417-22.
1988: Zhou M X; Chang T M
Control release of prostaglandin E2 from polylactic acid microcapsules, microparticles and modified microparticles.
Journal of microencapsulation 1988;5(1):27-36.
1988: Gu K F; Chang T M
Conversion of ammonia or urea into L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+. Glucose dehydrogenase for co-factor recycling.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(1):24-8.
1988: Chang T M
Medical applications of artificial cells in transfusion, phenylketonuria, essential amino acid production, and liver support.
Annals of the New York Academy of Sciences 1988;542():507-14.
1988: Chang T M; Varma R
Immunological and systemic effects of transfusions in rats using pyridoxylated hemoglobin and polyhemoglobin from homologous and heterogeneous sources.
Biomaterials, artificial cells, and artificial organs 1988;16(1-3):205-15.
1988: Keipert P E; Chang T M
Pyridoxylated-polyhemoglobin solution: a low viscosity oxygen-delivering blood replacement fluid with normal oncotic pressure and long-term storage feasibility.
Biomaterials, artificial cells, and artificial organs 1988;16(1-3):185-96.
1988: Chang T M; Lister C
Plasma/intestinal concentration patterns suggestive of entero-portal recirculation of amino acids: effects of oral administration of asparaginase, glutaminase and tyrosinase immobilized by microencapsulation in artificial cells.
Biomaterials, artificial cells, and artificial organs 1988;16(5):915-26.
1988: Chang T M
Artificial cells with ultrathin lipid-polymer or lipid-protein membranes.
Advances in experimental medicine and biology 1988;238():215-23.
1988: Kashani S A; Chang T M
Release of hepatic stimulatory substance from cultures of free and microencapsulated hepatocytes: preliminary report.
Biomaterials, artificial cells, and artificial organs 1988;16(4):741-6.
1988: Wong H; Chang T M
The viability and regeneration of artificial cell microencapsulated rat hepatocyte xenograft transplants in mice.
Biomaterials, artificial cells, and artificial organs 1988;16(4):731-9.
1988: Chang T M
Red blood cell substitutes: microencapsulated hemoglobin and cross-linked hemoglobin including pyridoxylated polyhemoglobin & conjugated hemoglobin.
Biomaterials, artificial cells, and artificial organs 1988;16(1-3):11-29.
1987: Chang T M; Farmer M; Geyer R P; Moss G
Blood substitutes based on modified hemoglobin and fluorochemicals.
ASAIO transactions / American Society for Artificial Internal Organs 1987;33(4):819-23.
1987: Wolfe E A; Chang T M
Orally ingested microencapsulated urease and an adsorbent, zirconium phosphate, to remove urea in kidney failure.
The International journal of artificial organs 1987;10(4):269-74.
1987: Keipert P E; Chang T M
Effects of partial and total isovolemic exchange transfusion in fully conscious rats using pyridoxylated polyhemoglobin solution as a colloidal oxygen-delivering blood replacement fluid.
Vox sanguinis 1987;53(1):7-14.
1987: Dixit V; Chang T M
Effects of prostaglandin E2 on brain edema and liver histopathology in a galactosamine-induced fulminant hepatic failure rat model.
Biomaterials, artificial cells, and artificial organs 1987;15(3):559-73.
1987: Zhou M X; Chang T M
Effects of polylactic acid microcapsules containing prostaglandin E2 on the survival rates of grade II coma galactosamine induced fulminant hepatic failure rats.
Biomaterials, artificial cells, and artificial organs 1987;15(3):549-58.
1987: Gu K F; Chang T M
Conversion of urea or ammonia into essential amino acids (L-leucine, L-valine, and L-isoleucine) using multienzyme systems and NADH-dextran immobilised in artificial cells.
Biomaterials, artificial cells, and artificial organs 1987;15(1):297-303.
1987: Chang T M; Varma R
Pyridoxalated heterogenous and homologous polyhemoglobin and hemoglobin: systemic effects of replacement transfusion in rats previously received immunizing doses.
Biomaterials, artificial cells, and artificial organs 1987;15(2):443-51.
1987: Morley D; Chang T M
Effect of membrane thickness of collodion coated activated charcoal on adsorption of small and middle molecules.
Biomaterials, artificial cells, and artificial organs 1987;15(3):617-32.
1987: Chang T M
Applications of artificial cells in medicine and biotechnology.
Biomaterials, artificial cells, and artificial organs 1987;15(1):1-20.
1987: Chang T M
Modified hemoglobin as red blood cell substitutes.
Biomaterials, artificial cells, and artificial organs 1987;15(2):323-8.
1987: Ilan E; Chang T M
Conversion of ammonia to glutamate by L-glutamic dehydrogenase, alcohol dehydrogenase and NAD+ immobilized within lipid-polyamide polyethyleneimine microcapsules.
Advances in experimental medicine and biology 1987;223():189-92.
1986: Sipehia R; Chawla A S; Chang T M
Enhanced albumin binding to polypropylene beads via anhydrous ammonia gaseous plasma.
Biomaterials 1986;7(6):471-3.
1985: Chang T M; Barre P; Kuruvilla S
Long-term reduced time hemoperfusion-hemodialysis compared to standard dialysis: a preliminary crossover analysis.
Transactions - American Society for Artificial Internal Organs 1985;31():572-6.
1982: Chang T M; Barre P; Kuruvilla S; Messier D; Man N; Resurreccion E
Phase one clinical trial of a new composite artificial kidney: a single unit combining dialysis with hemoperfusion.
Transactions - American Society for Artificial Internal Organs 1982;28():43-8.

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