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Ta-Yuan Chang

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Ta-Yuan Chang; Ren-Yin Chen; Bing-Fang Hwang; Chiu-Shong Liu; Ven-Shing Wang; Bo-Ying Bao; Jim-Shoung Lai
Occupational noise exposure and incident hypertension in men: a prospective cohort study.
Steve Poirier; Peter Schu; Ta-Yuan Chang; William S Garver; Gaétan Mayer; Stephanie R Murphy; Nabil G Seidah
The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins.
Jiunn-Bey Pao; Ying-Pi Yang; Ta-Yuan Chang; Tzyh-Chyuan Hour; Chun-Nung Huang; Chao-Yuan Huang; Shu-Pin Huang; Shin-Hun Juang; Yu-Hsuan Lan; Hong-Zin Lee; Te-Ling Lu; Bo-Ying Bao
Vitamin D receptor gene variants and clinical outcomes after androgen-deprivation therapy for prostate cancer.

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2013: Ta-Yuan Chang; Ren-Yin Chen; Bing-Fang Hwang; Chiu-Shong Liu; Ven-Shing Wang; Bo-Ying Bao; Jim-Shoung Lai
Occupational noise exposure and incident hypertension in men: a prospective cohort study.
American journal of epidemiology 2013;177(8):818-25.
2013: Steve Poirier; Peter Schu; Ta-Yuan Chang; William S Garver; Gaétan Mayer; Stephanie R Murphy; Nabil G Seidah
The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins.
Traffic (Copenhagen, Denmark) 2013;14(4):458-69.
2013: Jiunn-Bey Pao; Ying-Pi Yang; Ta-Yuan Chang; Tzyh-Chyuan Hour; Chun-Nung Huang; Chao-Yuan Huang; Shu-Pin Huang; Shin-Hun Juang; Yu-Hsuan Lan; Hong-Zin Lee; Te-Ling Lu; Bo-Ying Bao
Vitamin D receptor gene variants and clinical outcomes after androgen-deprivation therapy for prostate cancer.
World journal of urology 2013;31(2):281-7.
2013: Wen-Chien Ting; Ying-Pi Yang; Bang-Jau You; Ta-Yuan Chang; Lu-Min Chen; Yu-Hsuan Lan; Hong-Zin Lee; Jiunn-Bey Pao; Bo-Ying Bao
Common genetic variants in Wnt signaling pathway genes as potential prognostic biomarkers for colorectal cancer.
PloS one 2013;8(2):e56196.
2013: Chia-Cheng Yu; Ta-Yuan Chang; Tzyh-Chyuan Hour; Chun-Hsiung Huang; Chun-Nung Huang; Chao-Yuan Huang; Shu-Pin Huang; Yung-Chin Lee; Chia-Chu Liu; Bang-Jau You; Bo-Ying Bao
Molecular markers in sex hormone pathway genes associated with the efficacy of androgen-deprivation therapy for prostate cancer.
PloS one 2013;8(1):e54627.
2012: Ta-Yuan Chang; Hsiu-Hui Hsieh; Bo-Ying Bao; Chiu-Shong Liu; Jim-Shoung Lai
Effects of environmental noise exposure on 24-h ambulatory vascular properties in adults.
Environmental research 2012;118():112-7.
2012: Ven-Shing Wang; Ta-Yuan Chang; San-Yue Chen; Long-Chen Huang; Chien-Chen Lai; Keh-Ping Chao
Application of solid phase microextraction on dental composite resin analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;903():88-94.
2012: Ta-Yuan Chang; Hsiao-Ching Lin; Wei-Ting Yang; Bo-Ying Bao; Chang-Chuan Chan
A modified Nordic prediction model of road traffic noise in a Taiwanese city with significant motorcycle traffic.
The Science of the total environment 2012;432():375-81.
2012: Maximillian A Rogers; David Shapiro; Boris L Vaisman; Elena Bryleva; Catherine C Y Chang; Mark M Kushnir; Jay Liu; A Wayne Meikle; Alan T Remaley; Alan L Rockwood; Ta-Yuan Chang
Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase.
The Journal of biological chemistry 2012;287(21):17483-92.
2012: Bing-Fang Hwang; Ta-Yuan Chang; Kang-Yin Cheng; Chiu-Shong Liu
Gene-environment interaction between angiotensinogen and chronic exposure to occupational noise contribute to hypertension.
Occupational and environmental medicine 2012;69(4):236-42.
2012: Robert A Maue; Carlos A A Penatti; Donna M Porter; Maximillian A Rogers; Kevin Seburn; Benjamin S Szwergold; John W Totenhagen; Theodore P Trouard; marie T vanier; Bing Wang; Christine M Wooley; Ivan A Borbon; Robert W Burgess; Catherine C Chang; Ta-Yuan Chang; David J Graber; Brent T Harris; Leslie P Henderson; Robert P Erickson
A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.
Human molecular genetics 2012;21(4):730-50.
2012: Ta-Yuan Chang; Shen-En Jian; Chiu-Shong Liu; Ven-Shing Wang; Li-Hao Young; Bo-Ying Bao
Noise frequency components and the prevalence of hypertension in workers.
The Science of the total environment 2012;416():89-96.
2011: Ta-Yuan Chang; Chiu-Shong Liu; Bo-Ying Bao; Su-Fei Li; Tzu-I Chen; Yen-Ju Lin
Characterization of road traffic noise exposure and prevalence of hypertension in central Taiwan.
The Science of the total environment 2011;409(6):1053-7.
2011: Bo-Ying Bao; Jiunn-Bey Pao; Chun-Nung Huang; Yeong-Shiau Pu; Ta-Yuan Chang; Yu-Hsuan Lan; Te-Ling Lu; Hong-Zin Lee; Shin-Hun Juang; Lu-Min Chen; Chi-Jeng Hsieh; Shu-Pin Huang
Polymorphisms inside microRNAs and microRNA target sites predict clinical outcomes in prostate cancer patients receiving androgen-deprivation therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(4):928-36.
2011: Shu-Pin Huang; Yu-Hsuan Lan; Te-Ling Lu; Jiunn-Bey Pao; Ta-Yuan Chang; Hong-Zin Lee; Wen-Hui Yang; Chi-Jeng Hsieh; Lu-Min Chen; Li-Chia Huang; Wen-Chien Ting; Bo-Ying Bao
Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer.
BJU international 2011;107(3):486-92.
2011: Ta-Yuan Chang; Chiu-Shong Liu; Kuei-Hung Huang; Ren-Yin Chen; Jim-Shoung Lai; Bo-Ying Bao
High-frequency hearing loss, occupational noise exposure and hypertension: a cross-sectional study in male workers.
Environmental health : a global access science source 2011;10():35.
2010: Catherine C Y Chang; Akira Miyazaki; Ruhong Dong; Alireza Kheirollah; Chunjiang Yu; Yong Geng; Henry N Higgs; Ta-Yuan Chang
Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescence spectroscopy.
Biochemistry 2010;49(46):9957-63.
2010: Bo-Ying Bao; Jiunn-Bey Pao; Victor C Lin; Chun-Nung Huang; Ta-Yuan Chang; Yu-Hsuan Lan; Te-Ling Lu; Hong-Zin Lee; Lu-Min Chen; Wen-Chien Ting; Chi-Jeng Hsieh; Shu-Pin Huang
Individual and cumulative association of prostate cancer susceptibility variants with clinicopathologic characteristics of the disease.
Clinica chimica acta; international journal of clinical chemistry 2010;411(17-18):1232-7.
2010: XiaoFeng Lei; Yukio Fujiwara; Catherine C Y Chang; Ta-Yuan Chang; Motohiro Takeya; Naomi Sakashita
Association of ACAT1-positive vesicles with late endosomes/ lysosomes in cholesterol-rich human macrophages.
Journal of atherosclerosis and thrombosis 2010;17(7):740-50.
2010: Ta-Yuan Chang; Kuei-Hung Huang; Chiu-Shong Liu; Ruei-Hao Shie; Keh-Ping Chao; Wen-Hsin Hsu; Bo-Ying Bao
Exposure to volatile organic compounds and kidney dysfunction in thin film transistor liquid crystal display (TFT-LCD) workers.
Journal of hazardous materials 2010;178(1-3):934-40.
2010: Naomi Sakashita; Catherine C Y Chang; Xiaofeng Lei; Yukio Fujiwara; Motohiro Takeya; Ta-Yuan Chang
Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity.
Journal of lipid research 2010;51(6):1263-72.
2010: Bo-Ying Bao; Victor C Lin; Shu-Hung Huang; Jiunn-Bey Pao; Ta-Yuan Chang; Te-Ling Lu; Yu-Hsuan Lan; Lu-Min Chen; Wen-Chien Ting; Wen-Hui Yang; Chi-Jeng Hsieh; Shu-Pin Huang
Clinical significance of tumor necrosis factor receptor superfamily member 11b polymorphism in prostate cancer.
Annals of surgical oncology 2010;17(6):1675-81.
2010: Ta-Yuan Chang; Catherine C Y Chang; Elena Bryleva; Maximillian A Rogers; Stephanie R Murphy
Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease.
IUBMB life 2010;62(4):261-7.
2010: Elena Y Bryleva; Maximillian A Rogers; Catherine C Y Chang; Floyd Buen; Brent T Harris; Estelle Rousselet; Nabil G Seidah; Salvatore Oddo; Frank M LaFerla; Thomas A Spencer; William F Hickey; Ta-Yuan Chang
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3081-6.
2010: Ta-Yuan Chang; Shen-Ju Lin; Ruei-Hao Shie; Shih-Wei Tsai; Hui-Tsung Hsu; Ching-Tsan Tsai; Hsien-Wen Kuo; Chow-Feng Chiang; Jim-Shoung Lai
Characterization of volatile organic compounds in the vicinity of an optoelectronics industrial park in Taiwan.
Journal of the Air & Waste Management Association (1995) 2010;60(1):55-62.
2010: Ta-Yuan Chang; Ven-Shing Wang; Shou-Yu Lin; Hsin-Yu Yen; Jim-Shoung Lai; Chiu-Shong Liu
Co-exposure to noise, N,N-dimethylformamide, and toluene on 24-hour ambulatory blood pressure in synthetic leather workers.
Journal of occupational and environmental hygiene 2010;7(1):14-22.
2010: Shu-Pin Huang; Wen-Chien Ting; Lu-Min Chen; Li-Chia Huang; Chia-Chu Liu; Chien-Wei Chen; Chi-Jeng Hsieh; Wen-Hui Yang; Ta-Yuan Chang; Hong-Zin Lee; Bo-Ying Bao
Association analysis of Wnt pathway genes on prostate-specific antigen recurrence after radical prostatectomy.
Annals of surgical oncology 2010;17(1):312-22.
2009: Shu-Pin Huang; Li-Chia Huang; Wen-Chien Ting; Lu-Min Chen; Ta-Yuan Chang; Te-Ling Lu; Yu-Hsuan Lan; Chia-Chu Liu; Wen-Hui Yang; Hong-Zin Lee; Chi-Jeng Hsieh; Bo-Ying Bao
Prognostic significance of prostate cancer susceptibility variants on prostate-specific antigen recurrence after radical prostatectomy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):3068-74.
2009: Ta-Yuan Chang; Yu-An Lai; Hsiu-Hui Hsieh; Jim-Shoung Lai; Chiu-Shong Liu
Effects of environmental noise exposure on ambulatory blood pressure in young adults.
Environmental research 2009;109(7):900-5.
2009: Ta-Yuan Chang; Bo-Liang Li; Catherine C Y Chang; Yasuomi Urano
Acyl-coenzyme A:cholesterol acyltransferases.
American journal of physiology. Endocrinology and metabolism 2009;297(1):E1-9.
2009: Lei Lei; Ying Xiong; Jia Chen; Jin-Bo Yang; Yi Wang; Xin-Ying Yang; Catherine C Y Chang; Bao-Liang Song; Ta-Yuan Chang; Bo-Liang Li
TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation.
Journal of lipid research 2009;50(6):1057-67.
2009: Ta-Yuan Chang; Ven-Shing Wang; Bing-Fang Hwang; Hsin-Yu Yen; Jim-Shoung Lai; Chiu-Shong Liu; Shou-Yu Lin
Effects of co-exposure to noise and mixture of organic solvents on blood pressure.
Journal of occupational health 2009;51(4):332-9.
2008: Yasuomi Urano; Hiroshi Watanabe; Stephanie R Murphy; Yohei Shibuya; Yong Geng; Andrew A Peden; Catherine C Y Chang; Ta-Yuan Chang
Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16513-8.
2008: Jia Chen; Xiao-Nan Zhao; Li Yang; Guang-Jing Hu; Ming Lu; Ying Xiong; Xin-Ying Yang; Catherine C Y Chang; Bao-Liang Song; Ta-Yuan Chang; Bo-Liang Li
RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform.
Cell research 2008;18(9):921-36.
2008: Ta-Yuan Chang; Catherine Chang
Ezetimibe blocks internalization of the NPC1L1/cholesterol complex.
Cell metabolism 2008;7(6):469-71.
2008: Patrick C Reid; Song Lin; marie T vanier; Yoshiko Ohno-Iwashita; H James Harwood; William F Hickey; Catherine C Y Chang; Ta-Yuan Chang
Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation.
Journal of neuroscience methods 2008;168(1):15-25.
2007: Yoshio Yamauchi; Patrick C Reid; Jeffrey B Sperry; Koichi Furukawa; Motohiro Takeya; Catherine C Y Chang; Ta-Yuan Chang
Plasma membrane rafts complete cholesterol synthesis by participating in retrograde movement of precursor sterols.
The Journal of biological chemistry 2007;282(48):34994-5004.
2007: Ta-Yuan Chang; Ta-Chen Su; Shou-Yu Lin; Ruei-Man Jain; Chang-Chuan Chan
Effects of occupational noise exposure on 24-hour ambulatory vascular properties in male workers.
Environmental health perspectives 2007;115(11):1660-4.
2007: Zhan-Yun Guo; Catherine C Y Chang; Ta-Yuan Chang
Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1.
Biochemistry 2007;46(35):10063-71.
2006: Shigeki Sugii; Song Lin; Nobutaka Ohgami; Masato Ohashi; Catherine C Y Chang; Ta-Yuan Chang
Roles of endogenously synthesized sterols in the endocytic pathway.
The Journal of biological chemistry 2006;281(32):23191-206.
2006: Bao-Liang Song; Can-Hua Wang; Xiao-Min Yao; Li Yang; Wen-Jing Zhang; Zhen-Zhen Wang; Xiao-Nan Zhao; Jin-Bo Yang; Wei Qi; Xin-Ying Yang; Kenji Inoue; Zhi-Xin Lin; Hui-Zhan Zhang; Tatsuhiko Kodama; Catherine C Y Chang; Yin-Kun Liu; Ta-Yuan Chang; Bo-Liang Li
Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.
The Biochemical journal 2006;394(Pt 3):617-26.
2006: Catherine Chang; Ruhong Dong; Akira Miyazaki; Naomi Sakashita; Yi Zhang; Jay Liu; Michael Guo; Bo-Liang Li; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis.
Acta biochimica et biophysica Sinica 2006;38(3):151-6.
2006: Chang-Chuan Chan; Ruei-Hao Shie; Ta-Yuan Chang; Dai-Hua Tsai
Workers' exposures and potential health risks to air toxics in a petrochemical complex assessed by improved methodology.
International archives of occupational and environmental health 2006;79(2):135-42.
2006: Bo-Liang Li; Ta-Yuan Chang; Jia Chen; Catherine Cy Chang; Xiao-Nan Zhao
Human ACAT1 gene expression and its involvement in the development of atherosclerosis.
Future cardiology 2006;2(1):93-9.
2006: Ta-Yuan Chang; Catherine C Y Chang; Nobutaka Ohgami; Yoshio Yamauchi
Cholesterol sensing, trafficking, and esterification.
Annual review of cell and developmental biology 2006;22():129-57.
2005: Xiao-Min Yao; Can-Hua Wang; Bao-Liang Song; Xin-Ying Yang; Zhen-Zhen Wang; Wei Qi; Zhi-Xin Lin; Catherine C Y Chang; Ta-Yuan Chang; Bo-Liang Li
Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes.
Acta biochimica et biophysica Sinica 2005;37(12):797-806.
2005: Zhan-Yun Guo; Song Lin; Jennifer A Heinen; Catherine C Y Chang; Ta-Yuan Chang
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain.
The Journal of biological chemistry 2005;280(45):37814-26.
2005: Jay Liu; Catherine C Y Chang; Emily J Westover; Douglas F Covey; Ta-Yuan Chang
Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies.
The Biochemical journal 2005;391(Pt 2):389-97.
2005: Colleen A Paul; Patrick C Reid; Aimee K Boegle; Barbara Karten; M Zhang; Zhi-Gang Jiang; D Franz; L Lin; Ta-Yuan Chang; Jean E Vance; J Blanchette-Mackie; Robert A Maue
Adenovirus expressing an NPC1-GFP fusion gene corrects neuronal and nonneuronal defects associated with Niemann pick type C disease.
Journal of neuroscience research 2005;81(5):706-19.
2005: Ta-Yuan Chang; Patrick C Reid; Shigeki Sugii; Nobutaka Ohgami; Cruz Jonathan; Catherine C Y Chang
Niemann-Pick type C disease and intracellular cholesterol trafficking.
The Journal of biological chemistry 2005;280(22):20917-20.
2005: Zhan-Yun Guo; Catherine C Y Chang; Xiaohui Lu; Jiang Chen; Bo-Liang Li; Ta-Yuan Chang
The disulfide linkage and the free sulfhydryl accessibility of acyl-coenzyme A:cholesterol acyltransferase 1 as studied by using mPEG5000-maleimide.
Biochemistry 2005;44(17):6537-46.
2004: Li Yang; Oneil Lee; Jia Chen; Jiang Chen; Catherine C Y Chang; Pei Zhou; Zhen-Zhen Wang; Han-Hui Ma; Hui-fang Sha; Jiu-xian Feng; Yi Wang; Xin-Ying Yang; Li Wang; Ruhong Dong; Kim Ornvold; Bo-Liang Li; Ta-Yuan Chang
Human acyl-coenzyme A:cholesterol acyltransferase 1 (acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with additional sequence at the N terminus.
The Journal of biological chemistry 2004;279(44):46253-62.
2004: Yoshio Yamauchi; Catherine C Y Chang; Michi Hayashi; Sumiko Abe-Dohmae; Patrick C Reid; Ta-Yuan Chang; Shinji Yokoyama
Intracellular cholesterol mobilization involved in the ABCA1/apolipoprotein-mediated assembly of high density lipoprotein in fibroblasts.
Journal of lipid research 2004;45(10):1943-51.
2004: Nobutaka Ohgami; Dennis C Ko; Matthew Thomas; Matthew P Scott; Catherine C Y Chang; Ta-Yuan Chang
Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12473-8.
2004: Li Yang; Jin-Bo Yang; Jia Chen; Guang Yao Yu; Pei Zhou; Lei Lei; Zhen-Zhen Wang; Catherine Cy Chang; Xin Ying Yang; Ta-Yuan Chang; Bo-Liang Li
Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone.
Cell research 2004;14(4):315-23.
2004: Li Yang; Jiang Chen; Catherine C Y Chang; Xin-Ying Yang; Zhen-Zhen Wang; Ta-Yuan Chang; Bo-Liang Li
A stable upstream stem-loop structure enhances selection of the first 5'-ORF-AUG as a main start codon for translation initiation of human ACAT1 mRNA.
Acta biochimica et biophysica Sinica 2004;36(4):259-68.
2004: Ta-Yuan Chang; Lukas Jyuhn-Hsiarn Lee; Jung-Der Wang; Ruei-Hao Shie; Chang-Chuan Chan
Occupational risk assessment on allergic contact dermatitis in a resin model making process.
Journal of occupational health 2004;46(2):148-52.
2004: Patrick C Reid; Naomi Sakashita; Shigeki Sugii; Yoshiko Ohno-Iwashita; Yukiko Shimada; William F Hickey; Ta-Yuan Chang
A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain.
Journal of lipid research 2004;45(3):582-91.
2003: Ta-Yuan Chang; Ruei-Man Jain; Chiu-Sen Wang; Chang-Chuan Chan
Effects of occupational noise exposure on blood pressure.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2003;45(12):1289-96.
2003: Naomi Sakashita; Akira Miyazaki; Catherine C Y Chang; Ta-Yuan Chang; Emi Kiyota; Maki Satoh; Yoshihiro Komohara; Peter M Morganelli; Seikoh Horiuchi; Motohiro Takeya
Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies.
Laboratory investigation; a journal of technical methods and pathology 2003;83(11):1569-81.
2003: Chang-Chuan Chan; Yi-Ping Lin; Hsiu-Hsi Chen; Ta-Yuan Chang; Tsun-Jen Cheng; Li-Sheng Chen
A population-based study on the immediate and prolonged effects of the 1999 Taiwan earthquake on mortality.
Annals of epidemiology 2003;13(7):502-8.
2003: Shigeki Sugii; Patrick C Reid; Nobutaka Ohgami; Hong Du; Ta-Yuan Chang
Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol.
The Journal of biological chemistry 2003;278(29):27180-9.
2003: Song Lin; Xiaohui Lu; Catherine C Y Chang; Ta-Yuan Chang
Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location.
Molecular biology of the cell 2003;14(6):2447-60.
2003: Patrick C Reid; Shigeki Sugii; Ta-Yuan Chang
Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice.
Journal of lipid research 2003;44(5):1010-9.
2003: Shigeki Sugii; Patrick C Reid; Nobutaka Ohgami; Yukiko Shimada; Robert A Maue; Haruaki Ninomiya; Yoshiko Ohno-Iwashita; Ta-Yuan Chang
Biotinylated theta-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells.
Journal of lipid research 2003;44(5):1033-41.
2003: Volker Wiegand; Ta-Yuan Chang; Jerome F Strauss; Falk Fahrenholz; Gerald Gimpl
Transport of plasma membrane-derived cholesterol and the function of Niemann-Pick C1 Protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):782-4.
2003: Yi Zhang; CHUNJIANG YU; Jay Liu; Thomas A Spencer; Catherine C Y Chang; Ta-Yuan Chang
Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1.
The Journal of biological chemistry 2003;278(13):11642-7.
2003: Naoya Sawamura; Jian-Sheng Gong; Ta-Yuan Chang; Katsuhiko Yanagisawa; Makoto Michikawa
Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells.
Journal of neurochemistry 2003;84(5):1086-96.
2003: Nadeem Khan; Jiangang Shen; Ta-Yuan Chang; Catherine C Chang; Peter C W Fung; Oleg Y Grinberg; Eugene Demidenko; Harold Swartz
Plasma membrane cholesterol: a possible barrier to intracellular oxygen in normal and mutant CHO cells defective in cholesterol metabolism.
Biochemistry 2003;42(1):23-9.
2002: Cruz Jonathan; Matthew Thomas; Edmund Wong; Nobutaka Ohgami; Shigeki Sugii; Thomas Curphey; Catherine C Y Chang; Ta-Yuan Chang
Synthesis and biochemical properties of a new photoactivatable cholesterol analog 7,7-azocholestanol and its linoleate ester in Chinese hamster ovary cell lines.
Journal of lipid research 2002;43(8):1341-7.
2002: Michael Buszczak; Xiaohui Lu; William A Segraves; Ta-Yuan Chang; Lynn Cooley
Mutations in the midway gene disrupt a Drosophila acyl coenzyme A: diacylglycerol acyltransferase.
Genetics 2002;160(4):1511-8.
2002: CHUNJIANG YU; Yi Zhang; Xiaohui Lu; Jun Chen; Catherine C Y Chang; Ta-Yuan Chang
Role of the N-terminal hydrophilic domain of acyl-coenzyme A:cholesterol acyltransferase 1 on the enzyme's quaternary structure and catalytic efficiency.
Biochemistry 2002;41(11):3762-9.
2002: Xiaohui Lu; Song Lin; Catherine C Y Chang; Ta-Yuan Chang
Mutant acyl-coenzyme A:cholesterol acyltransferase 1 devoid of cysteine residues remains catalytically active.
The Journal of biological chemistry 2002;277(1):711-8.
2001: Ta-Yuan Chang; Catherine C Y Chang; Xiaohui Lu; Song Lin
Catalysis of ACAT may be completed within the plane of the membrane: a working hypothesis.
Journal of lipid research 2001;42(12):1933-8.
2001: Jin-Bo Yang; Z J Duan; W Yao; Oneil Lee; Li Yang; Xin-Ying Yang; X Sun; Catherine C Y Chang; Ta-Yuan Chang; Bo-Liang Li
Synergistic transcriptional activation of human Acyl-coenzyme A: cholesterol acyltransterase-1 gene by interferon-gamma and all-trans-retinoic acid THP-1 cells.
The Journal of biological chemistry 2001;276(24):20989-98.
2001: Ta-Yuan Chang; Catherine C Y Chang; Song Lin; CHUNJIANG YU; Bo-Liang Li; Akira Miyazaki
Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2.
Current opinion in lipidology 2001;12(3):289-96.
2001: Bao-Liang Song; Wei Qi; Xin-Ying Yang; Catherine C Y Chang; J Q Zhu; Ta-Yuan Chang; Bo-Liang Li
Organization of human ACAT-2 gene and its cell-type-specific promoter activity.
Biochemical and biophysical research communications 2001;282(2):580-8.
2001: KK Maung; Akira Miyazaki; H Nomiyama; Catherine C Y Chang; Ta-Yuan Chang; Seikoh Horiuchi
Induction of acyl-coenzyme A:cholesterol acyltransferase-1 by 1,25-dihydroxyvitamin D(3) or 9-cis-retinoic acid in undifferentiated THP-1 cells.
Journal of lipid research 2001;42(2):181-7.
2000: Cruz Jonathan; Ta-Yuan Chang
Fate of endogenously synthesized cholesterol in Niemann-Pick type C1 cells.
The Journal of biological chemistry 2000;275(52):41309-16.
2000: Catherine C Y Chang; Naomi Sakashita; Kim Ornvold; Oneil Lee; ET Chang; Ruhong Dong; Song Lin; C Y Lee; Stephen C Strom; R Kashyap; J J Fung; R V Farese; Jean-François Patoiseau; André Delhon; Ta-Yuan Chang
Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine.
The Journal of biological chemistry 2000;275(36):28083-92.
2000: Leslie P Henderson; L Lin; A Prasad; Colleen A Paul; Ta-Yuan Chang; Robert A Maue
Embryonic striatal neurons from niemann-pick type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness.
The Journal of biological chemistry 2000;275(26):20179-87.
2000: Cruz Jonathan; Shigeki Sugii; CHUNJIANG YU; Ta-Yuan Chang
Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.
The Journal of biological chemistry 2000;275(6):4013-21.
2000: Naomi Sakashita; Akira Miyazaki; Motohiro Takeya; Seikoh Horiuchi; Catherine C Y Chang; Ta-Yuan Chang; Kiyoshi Takahashi
Localization of human acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues.
The American journal of pathology 2000;156(1):227-36.
1999: CHUNJIANG YU; Jun Chen; Song Lin; Jay Liu; Catherine C Y Chang; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro.
The Journal of biological chemistry 1999;274(51):36139-45.
1999: Song Lin; D Cheng; M S Liu; Jun Chen; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.
The Journal of biological chemistry 1999;274(33):23276-85.
1999: Bo-Liang Li; X L Li; Z J Duan; Oneil Lee; Song Lin; Z M Ma; Catherine C Y Chang; Xin-Ying Yang; Jonathan P Park; Thuluvancheri K Mohandas; Walter W Noll; L Chan; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene organization and evidence that the 4.3-kilobase ACAT-1 mRNA is produced from two different chromosomes.
The Journal of biological chemistry 1999;274(16):11060-71.
1998: Catherine C Y Chang; C Y Lee; ET Chang; Cruz Jonathan; M C Levesque; Ta-Yuan Chang
Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.
The Journal of biological chemistry 1998;273(52):35132-41.
1998: Akira Miyazaki; Naomi Sakashita; Oneil Lee; Kiyoshi Takahashi; Seikoh Horiuchi; Hideki Hakamata; Peter M Morganelli; Catherine C Y Chang; Ta-Yuan Chang
Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(10):1568-74.
1998: Oneil Lee; Catherine C Y Chang; W Lee; Ta-Yuan Chang
Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines.
Journal of lipid research 1998;39(8):1722-7.
1997: Ta-Yuan Chang; M T Hasan; J Chin; Catherine C Y Chang; D M Spillane; J Chen
Chinese hamster ovary cell mutants affecting cholesterol metabolism.
Current opinion in lipidology 1997;8(2):65-71.
1997: Ta-Yuan Chang; Catherine C Y Chang; D Cheng
Acyl-coenzyme A:cholesterol acyltransferase.
Annual review of biochemistry 1997;66():613-38.
1996: H Matsuda; Hideki Hakamata; Akira Miyazaki; Masakazu Sakai; Catherine C Y Chang; Ta-Yuan Chang; S Kobori; Motoaki Shichiri; Seikoh Horiuchi
Activation of acyl-coenzyme A:cholesterol acyltransferase activity by cholesterol is not due to altered mRNA levels in HepG2 cells.
Biochimica et biophysica acta 1996;1301(1-2):76-84.
1995: Catherine C Y Chang; J Chen; M A Thomas; D Cheng; V A Del Priore; Roger S Newton; Michael E Pape; Ta-Yuan Chang
Regulation and immunolocalization of acyl-coenzyme A: cholesterol acyltransferase in mammalian cells as studied with specific antibodies.
The Journal of biological chemistry 1995;270(49):29532-40.
1995: D M Spillane; J W Reagan; N J Kennedy; D L Schneider; Ta-Yuan Chang
Translocation of both lysosomal LDL-derived cholesterol and plasma membrane cholesterol to the endoplasmic reticulum for esterification may require common cellular factors involved in cholesterol egress from the acidic compartments (lysosomes/endosomes).
Biochimica et biophysica acta 1995;1254(3):283-94.
1995: D Cheng; Catherine C Y Chang; X Qu; Ta-Yuan Chang
Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system.
The Journal of biological chemistry 1995;270(2):685-95.
1994: M T Hasan; Ta-Yuan Chang
Somatic cell genetic analysis of two classes of CHO cell mutants expressing opposite phenotypes in sterol-dependent regulation of cholesterol metabolism.
Somatic cell and molecular genetics 1994;20(6):481-91.
1994: Ta-Yuan Chang; Catherine C Y Chang; K M Cadigan
The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosis.
Trends in cardiovascular medicine 1994;4(5):223-30.
1994: M T Hasan; Catherine C Y Chang; Ta-Yuan Chang
Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression.
Somatic cell and molecular genetics 1994;20(3):183-94.
1994: Catherine C Y Chang; Walter W Noll; N Nutile-McMenemy; E A Lindsay; A Baldini; W Chang; Ta-Yuan Chang
Localization of acyl coenzyme A:cholesterol acyltransferase gene to human chromosome 1q25.
Somatic cell and molecular genetics 1994;20(1):71-4.
1993: Catherine C Y Chang; H Y Huh; K M Cadigan; Ta-Yuan Chang
Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.
The Journal of biological chemistry 1993;268(28):20747-55.
1991: M T Hasan; R Subbaroyan; Ta-Yuan Chang
High-efficiency stable gene transfection using chloroquine-treated Chinese hamster ovary cells.
Somatic cell and molecular genetics 1991;17(5):513-7.
1990: K M Cadigan; D M Spillane; Ta-Yuan Chang
Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking.
The Journal of cell biology 1990;110(2):295-308.
1989: S P Shi; Catherine C Y Chang; G W Gould; Ta-Yuan Chang
Comparison of phosphatidylethanolamine and phosphatidylcholine vesicles produced by treating cholate-phospholipid micelles with cholestyramine.
Biochimica et biophysica acta 1989;982(2):187-95.
1989: K M Cadigan; Catherine C Y Chang; Ta-Yuan Chang
Isolation of Chinese hamster ovary cell lines expressing human acyl-coenzyme A/cholesterol acyltransferase activity.
The Journal of cell biology 1989;108(6):2201-10.
1988: K M Cadigan; Ta-Yuan Chang
A simple method for reconstitution of CHO cell and human fibroblast acyl coenzyme A: cholesterol acyltransferase activity into liposomes.
Journal of lipid research 1988;29(12):1683-92.
1988: K M Cadigan; J G Heider; Ta-Yuan Chang
Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity.
The Journal of biological chemistry 1988;263(1):274-82.
1986: J B Ventimiglia; M C Levesque; Ta-Yuan Chang
Preparation and characterization of unilamellar vesicles from cholate-phospholipid micelle treated with cholestyramine.
Analytical biochemistry 1986;157(2):323-30.