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Yen Chang

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Pericardium

Procedures

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Publications

TOP 3
Chieh-Cheng Huang; Yi-Wen Hung; Shiaw-Min Hwang; Wen-Yu Lee; Wei-Wen Lin; Yen Chang; Ding-Yuan Chen; Jee-Wei Chen; Hung-Wen Tsai; Hsing-Wen Sung
A translational approach in using cell sheet fragments of autologous bone marrow-derived mesenchymal stem cells for cellular cardiomyoplasty in a porcine model.
Ding-Yuan Chen; Ko-Jie Chen; Chieh-Cheng Huang; Kun-Ju Lin; Yen Chang; Ko-Ting Chao; Chung-Chi Wang; Hao-Ji Wei; Cheng-Tse Wu; Hsing-Wen Sung
Three-dimensional cell aggregates composed of HUVECs and cbMSCs for therapeutic neovascularization in a mouse model of hindlimb ischemia.
Chun-Wen Hsiao; Ting-Yin Lee; Ren-Ke Li; Zi-Xian Liao; Barnali Maiti; Meng-Yi Bai; Yen Chang; Min-Fan Chung; Cheng-Tse Wu; Hsing-Wen Sung
Electrical coupling of isolated cardiomyocyte clusters grown on aligned conductive nanofibrous meshes for their synchronized beating.

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All Publications

2013: Chieh-Cheng Huang; Yi-Wen Hung; Shiaw-Min Hwang; Wen-Yu Lee; Wei-Wen Lin; Yen Chang; Ding-Yuan Chen; Jee-Wei Chen; Hung-Wen Tsai; Hsing-Wen Sung
A translational approach in using cell sheet fragments of autologous bone marrow-derived mesenchymal stem cells for cellular cardiomyoplasty in a porcine model.
Biomaterials 2013;34(19):4582-91.
2013: Ding-Yuan Chen; Ko-Jie Chen; Chieh-Cheng Huang; Kun-Ju Lin; Yen Chang; Ko-Ting Chao; Chung-Chi Wang; Hao-Ji Wei; Cheng-Tse Wu; Hsing-Wen Sung
Three-dimensional cell aggregates composed of HUVECs and cbMSCs for therapeutic neovascularization in a mouse model of hindlimb ischemia.
Biomaterials 2013;34(8):1995-2004.
2013: Chun-Wen Hsiao; Ting-Yin Lee; Ren-Ke Li; Zi-Xian Liao; Barnali Maiti; Meng-Yi Bai; Yen Chang; Min-Fan Chung; Cheng-Tse Wu; Hsing-Wen Sung
Electrical coupling of isolated cardiomyocyte clusters grown on aligned conductive nanofibrous meshes for their synchronized beating.
Biomaterials 2013;34(4):1063-72.
2012: Chih-Chun Yang; Szu-Tsen Lai; Chung-Yu Lo; Hung-Wen Tsai; Hui Chung Wu; Yen Chang
Mediastinal diffuse large B-cell lymphoma invading the left atrium mimicking coronary artery disease with a mural thrombus.
Journal of the Chinese Medical Association : JCMA 2012;75(11):606-9.
2012: Chieh-Cheng Huang; Shiaw-Min Hwang; Ting-Yin Lee; Wei-Wen Lin; Jiun-Jie Wang; Hao-Ji Wei; Younan Xia; Yi-Chun Yeh; Yen Chang; Sung-Wook Choi; Hsing-Wen Sung
Injectable PLGA porous beads cellularized by hAFSCs for cellular cardiomyoplasty.
Biomaterials 2012;33(16):4069-77.
2012: Wen-Yu Lee; Kun-Ju Lin; Wei-Wen Lin; Hsiang-Yang Ma; Yen Chang; Ding-Yuan Chen; Chieh-Cheng Huang; Shiaw-Min Hwang; Ting-Yin Lee; Jiun-Jie Wang; Hao-Ji Wei; Hsing-Wen Sung
Vascularization and restoration of heart function in rat myocardial infarction using transplantation of human cbMSC/HUVEC core-shell bodies.
Biomaterials 2012;33(7):2127-36.
2011: Wen-Yu Lee; Hung-Wen Tsai; Yen Chang; Ding-Yuan Chen; Jen-Hao Chiang; Li-Wen Hsu; Yi-Wen Hung; Shiaw-Min Hwang; Hsing-Wen Sung
Core-shell cell bodies composed of human cbMSCs and HUVECs for functional vasculogenesis.
Biomaterials 2011;32(33):8446-55.
2011: Wen-Yu Lee; Hao-Ji Wei; Wei-Wen Lin; Yi-Chun Yeh; Shiaw-Min Hwang; Jiun-Jie Wang; Ming-Song Tsai; Yen Chang; Hsing-Wen Sung
Enhancement of cell retention and functional benefits in myocardial infarction using human amniotic-fluid stem-cell bodies enriched with endogenous ECM.
Biomaterials 2011;32(24):5558-67.
2011: Wei-Lin Tsai; I-Chen Tsai; Min-Chi Chen; Wan-Chun Liao; Yen Chang
Comprehensive evaluation of patients with suspected prosthetic heart valve disorders using MDCT.
AJR. American journal of roentgenology 2011;196(2):353-60.
2010: Yi-Chun Yeh; Wen-Yu Lee; Chu-Leng Yu; Shiaw-Min Hwang; Min-Fan Chung; Li-Wen Hsu; Yen Chang; Wei-Wen Lin; Ming-Song Tsai; Hao-Ji Wei; Hsing-Wen Sung
Cardiac repair with injectable cell sheet fragments of human amniotic fluid stem cells in an immune-suppressed rat model.
Biomaterials 2010;31(25):6444-53.
2010: Chieh-Cheng Huang; Chen-Kang Liao; Mei-Ju Yang; Chun-Hung Chen; Shiaw-Min Hwang; Yi-Wen Hung; Yen Chang; Hsing-Wen Sung
A strategy for fabrication of a three-dimensional tissue construct containing uniformly distributed embryoid body-derived cells as a cardiac patch.
Biomaterials 2010;31(24):6218-27.
2010: Sheng-Ling Jan; Shing-Jong Lin; Yun-Ching Fu; Ching-Shiang Chi; Chung-Chi Wang; Hao-Ji Wei; Yen Chang; Betau Hwang; Po-Yen Chen; Huang Fang-Liang; Ming-Chih Lin
Extracorporeal life support for treatment of children with enterovirus 71 infection-related cardiopulmonary failure.
Intensive care medicine 2010;36(3):520-7.
2009: Wen-Yu Lee; Yu-Hsiang Chang; Yi-Chun Yeh; Chun-Hung Chen; Kurt M Lin; Chieh-Cheng Huang; Yen Chang; Hsing-Wen Sung
The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation.
Biomaterials 2009;30(29):5505-13.
2009: Mei-Chin Chen; Chin-Tang Liu; Hung-Wen Tsai; Wei-Yun Lai; Yen Chang; Hsing-Wen Sung
Mechanical properties, drug eluting characteristics and in vivo performance of a genipin-crosslinked chitosan polymeric stent.
Biomaterials 2009;30(29):5560-71.
2009: Mei-Chin Chen; Hung-Wen Tsai; Chin-Tang Liu; Shu-Fen Peng; Wei-Yun Lai; Shiang-Jiuun Chen; Yen Chang; Hsing-Wen Sung
A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs.
Biomaterials 2009;30(11):2102-11.
2009: I-Chen Tsai; Yung-Kai Lin; Yen Chang; Yun-Ching Fu; Chung-Chi Wang; Shih-Rong Hsieh; Hao-Ji Wei; Hung-Wen Tsai; Sheng-Ling Jan; Kuo-Yang Wang; Min-Chi Chen; Clayton Chi-Chang Chen
Correctness of multi-detector-row computed tomography for diagnosing mechanical prosthetic heart valve disorders using operative findings as a gold standard.
European radiology 2009;19(4):857-67.
2009: Mei-Chin Chen; Yen Chang; Chin-Tang Liu; Wei-Yun Lai; Shu-Fen Peng; Yi-Wen Hung; Hung-Wen Tsai; Hsing-Wen Sung
The characteristics and in vivo suppression of neointimal formation with sirolimus-eluting polymeric stents.
Biomaterials 2009;30(1):79-88.
2008: Chun-Hung Chen; Hao-Ji Wei; Wei-Wen Lin; Iwen Chiu; Shiaw-Min Hwang; Chung-Chi Wang; Wen-Yu Lee; Yen Chang; Hsing-Wen Sung
Porous tissue grafts sandwiched with multilayered mesenchymal stromal cell sheets induce tissue regeneration for cardiac repair.
Cardiovascular research 2008;80(1):88-95.
2008: Hao-Ji Wei; Chun-Hung Chen; Wen-Yu Lee; Iwen Chiu; Shiaw-Min Hwang; Wei-Wen Lin; Chieh-Cheng Huang; Yi-Chun Yeh; Yen Chang; Hsing-Wen Sung
Bioengineered cardiac patch constructed from multilayered mesenchymal stem cells for myocardial repair.
Biomaterials 2008;29(26):3547-56.
2008: I-Chen Tsai; Wen-Lieng Lee; Chen-Rong Tsao; Yen Chang; Min-Chi Chen; Tain Lee; Wan-Chun Liao
Comprehensive evaluation of ischemic heart disease using MDCT.
AJR. American journal of roentgenology 2008;191(1):64-72.
2008: Chung-Chi Wang; Chun-Hung Chen; Wei-Wen Lin; Shiaw-Min Hwang; Patrick C H Hsieh; Po-Hong Lai; Yi-Chun Yeh; Yen Chang; Hsing-Wen Sung
Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction.
Cardiovascular research 2008;77(3):515-24.
2007: Chun-Hung Chen; Yen Chang; Chung-Chi Wang; Chih-Hao Huang; Chieh-Cheng Huang; Yi-Chun Yeh; Shiaw-Min Hwang; Hsing-Wen Sung
Construction and characterization of fragmented mesenchymal-stem-cell sheets for intramuscular injection.
Biomaterials 2007;28(31):4643-51.
2007: Mei-Chin Chen; Hung-Wen Tsai; Yen Chang; Wei-Yun Lai; Fwu-Long Mi; Chin-Tang Liu; Hen-Sheng Wong; Hsing-Wen Sung
Rapidly self-expandable polymeric stents with a shape-memory property.
Biomacromolecules 2007;8(9):2774-80.
2007: Hao-Ji Wei; Hang-Hsing Yang; Chun-Hung Chen; Wei-Wen Lin; Sung-Ching Chen; Po-Hong Lai; Yen Chang; Hsing-Wen Sung
Gelatin microspheres encapsulated with a nonpeptide angiogenic agent, ginsenoside Rg1, for intramyocardial injection in a rat model with infarcted myocardium.
Journal of controlled release : official journal of the Controlled Release Society 2007;120(1-2):27-34.
2007: Yen Chang; Po-Hong Lai; Hao-Ji Wei; Wei-Wen Lin; Chun-Hung Chen; Shiaw-Min Hwang; Sung-Ching Chen; Hsing-Wen Sung
Tissue regeneration observed in a basic fibroblast growth factor-loaded porous acellular bovine pericardium populated with mesenchymal stem cells.
The Journal of thoracic and cardiovascular surgery 2007;134(1):65-73, 73.e1-4.
2006: Hao-Ji Wei; Sung-Ching Chen; Yen Chang; Shiaw-Min Hwang; Wei-Wen Lin; Po-Hong Lai; Huihua Kenny Chiang; Lee-Feng Hsu; Hang-Hsing Yang; Hsing-Wen Sung
Porous acellular bovine pericardia seeded with mesenchymal stem cells as a patch to repair a myocardial defect in a syngeneic rat model.
Biomaterials 2006;27(31):5409-19.
2006: Yen Chang; Po-Hong Lai; Chung-Chi Wang; Sung-Ching Chen; Wei-Chun Chang; Hsing-Wen Sung
Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial adhesions.
The Journal of thoracic and cardiovascular surgery 2006;132(4):867-74.
2006: Po-Hong Lai; Yen Chang; Sung-Ching Chen; Chung-Chi Wang; Huang-Chien Liang; Wei-Chun Chang; Hsing-Wen Sung
Acellular biological tissues containing inherent glycosaminoglycans for loading basic fibroblast growth factor promote angiogenesis and tissue regeneration.
Tissue engineering 2006;12(9):2499-508.
2005: Yen Chang; Cheng-Kuo Hsu; Hao-Ji Wei; Sung-Ching Chen; Huang-Chien Liang; Po-Hong Lai; Hsing-Wen Sung
Cell-free xenogenic vascular grafts fixed with glutaraldehyde or genipin: in vitro and in vivo studies.
Journal of biotechnology 2005;120(2):207-19.
2005: Mei-Chin Chen; Hsiang-Fa Liang; Ya-Ling Chiu; Yen Chang; Hao-Ji Wei; Hsing-Wen Sung
A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus.
Journal of controlled release : official journal of the Controlled Release Society 2005;108(1):178-89.
2005: Yen Chang; Sung-Ching Chen; Hao-Ji Wei; Tsu-Juey Wu; Huang-Chien Liang; Po-Hong Lai; Hang-Hsing Yang; Hsing-Wen Sung
Tissue regeneration observed in a porous acellular bovine pericardium used to repair a myocardial defect in the right ventricle of a rat model.
The Journal of thoracic and cardiovascular surgery 2005;130(3):705-11.
2005: Po-Hong Lai; Yen Chang; Huang-Chien Liang; Sung-Ching Chen; Hao-Ji Wei; Hsing-Wen Sung
Peritoneal regeneration induced by an acellular bovine pericardial patch in the repair of abdominal wall defects.
The Journal of surgical research 2005;127(2):85-92.
2005: Huang-Chien Liang; Chiung-Tong Chen; Yen Chang; Ya-Chun Huang; Sung-Ching Chen; Hsing-Wen Sung
Loading of a novel angiogenic agent, ginsenoside Rg1 in an acellular biological tissue for tissue regeneration.
Tissue engineering 2005;11(5-6):835-46.
2005: Hao-Ji Wei; Huang-Chien Liang; Meng-Horng Lee; Ya-Chun Huang; Yen Chang; Hsing-Wen Sung
Construction of varying porous structures in acellular bovine pericardia as a tissue-engineering extracellular matrix.
Biomaterials 2005;26(14):1905-13.
2005: Ya-Chun Huang; Chiung-Tong Chen; Sung-Ching Chen; Po-Hong Lai; Huang-Chien Liang; Yen Chang; Lin-Chien Yu; Hsing-Wen Sung
A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration.
Pharmaceutical research 2005;22(4):636-46.
2004: Chung-Lin Tsai; Hao-Ji Wei; Shih-Rong Hsieh; Yen Chang
Salvage of left Cabrol limb occlusion by minimally invasive direct coronary bypass grafting.
Interactive cardiovascular and thoracic surgery 2004;3(4):678-81.
2004: Chien-Chang Chen; Chung-Chi Wang; Shih-Rong Hsieh; Hung-Wen Tsai; Hao-Ji Wei; Yen Chang
Application of European system for cardiac operative risk evaluation (EuroSCORE) in coronary artery bypass surgery for Taiwanese.
Interactive cardiovascular and thoracic surgery 2004;3(4):562-5.
2004: Huang-Chien Liang; Yen Chang; Cheng-Kuo Hsu; Meng-Horng Lee; Hsing-Wen Sung
Effects of crosslinking degree of an acellular biological tissue on its tissue regeneration pattern.
Biomaterials 2004;25(17):3541-52.
2004: Yi-Chien Chen; Wen-Hsiang Chang; Yen Chang; Chun-Ming Huang; Hsing-Wen Sung
A natural compound (reuterin) produced by Lactobacillus reuteri for hemoglobin polymerization as a blood substitute.
Biotechnology and bioengineering 2004;87(1):34-42.
2004: Hung-Wen Tsai; Shih-Rong Hsieh; Hao-Ji Wei; Chung-Chi Wang; Yen Chang; Hui-Ching Ho
Determinants of in-hospital mortality after surgery for acute type A aortic dissection.
Journal of the Formosan Medical Association = Taiwan yi zhi 2004;103(6):428-31.
2004: Hao-Ji Wei; Chung-Chi Wang; Shih-Rong Hsieh; Hung-Wen Tsai; Yen Chang
Feasibility and short-term results of total arterial coronary artery bypass in Taiwanese.
Journal of the Formosan Medical Association = Taiwan yi zhi 2004;103(6):422-7.
2004: Wen-Hsiang Chang; Yen Chang; Yi-Chien Chen; Hsing-Wen Sung
Hemoglobin polymerized with a naturally occurring crosslinking agent as a blood substitute: in vitro and in vivo studies.
Artificial cells, blood substitutes, and immobilization biotechnology 2004;32(2):243-62.
2004: Yen Chang; Meng-Horng Lee; Huang-Chien Liang; Cheng-Kuo Hsu; Hsing-Wen Sung
Acellular bovine pericardia with distinct porous structures fixed with genipin as an extracellular matrix.
Tissue engineering 2004;10(5-6):881-92.
2004: Yen Chang; Huang-Chien Liang; Hao-Ji Wei; Chih-Ping Chu; Hsing-Wen Sung
Tissue regeneration patterns in acellular bovine pericardia implanted in a canine model as a vascular patch.
Journal of biomedical materials research. Part A 2004;69(2):323-33.
2003: Hsiang-Fa Liang; Chiun-Nan Chen; Yen Chang; Hsing-Wen Sung
Natural antimicrobial agent (reuterin) produced by lactobacillus reuteri for sanitization of biological tissues inoculated with pseudomonas aeruginosa.
Biotechnology and bioengineering 2003;84(2):233-9.
2003: Yin-Tai Hong; Yun-Ching Fu; Chao-Huei Chen; Sheng-Ling Jan; Teh-Ming Wang; Yen Chang; Ching-Shiang Chi
Vascular ring due to double aortic arch with atretic left arch and left ligamentum arteriosum: report of one case.
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 2003;44(3):168-70.
2003: Yun-Ching Fu; Ching-Shiang Chi; Sheng-Ling Jan; Teh-Ming Wang; Po-Yen Chen; Yen Chang; Guan Chou; Chieh-Chung Lin; Betau Hwang; Shih-Lan Hsu
Pulmonary edema of enterovirus 71 encephalomyelitis is associated with left ventricular failure: implications for treatment.
Pediatric pulmonology 2003;35(4):263-8.
2003: Hung-Wen Tsai; Chung-Chi Wang; Hao-Ji Wei; Fong-Chung Lai; Shih-Rong Hsieh; Yen Chang
Mitral valve repair--early and medium-term results.
Journal of the Chinese Medical Association : JCMA 2003;66(3):173-6.
2003: Wen-Hsiang Chang; Yen Chang; Po-Hong Lai; Hsing-Wen Sung
A genipin-crosslinked gelatin membrane as wound-dressing material: in vitro and in vivo studies.
Journal of biomaterials science. Polymer edition 2003;14(5):481-95.
2002: Hsing-Wen Sung; Chiun-Nan Chen; Yen Chang; Hsiang-Fa Liang
Biocompatibility study of biological tissues fixed by a natural compound (reuterin) produced by Lactobacillus reuteri.
Biomaterials 2002;23(15):3203-14.
2002: Yen Chang; Chen-Chi Tsai; Huang-Chien Liang; Hsing-Wen Sung
In vivo evaluation of cellular and acellular bovine pericardia fixed with a naturally occurring crosslinking agent (genipin).
Biomaterials 2002;23(12):2447-57.
2001: Yen Chang; C C Tsai; Huang-Chien Liang; Hsing-Wen Sung
Reconstruction of the right ventricular outflow tract with a bovine jugular vein graft fixed with a naturally occurring crosslinking agent (genipin) in a canine model.
The Journal of thoracic and cardiovascular surgery 2001;122(6):1208-18.
2001: C C Tsai; Yen Chang; Hsing-Wen Sung; J C Hsu; C N Chen
Effects of heparin immobilization on the surface characteristics of a biological tissue fixed with a naturally occurring crosslinking agent (genipin): an in vitro study.
Biomaterials 2001;22(6):523-33.
2000: Hsing-Wen Sung; Yen Chang; IL Liang; Wen-Hsiang Chang; Yi-Chien Chen
Fixation of biological tissues with a naturally occurring crosslinking agent: fixation rate and effects of pH, temperature, and initial fixative concentration.
Journal of biomedical materials research 2000;52(1):77-87.
1999: Hsing-Wen Sung; Yen Chang; CT Chiu; Chiun-Nan Chen; Huang-Chien Liang
Crosslinking characteristics and mechanical properties of a bovine pericardium fixed with a naturally occurring crosslinking agent.
Journal of biomedical materials research 1999;47(2):116-26.
1999: Hsing-Wen Sung; Yen Chang; CT Chiu; Chiun-Nan Chen; Huang-Chien Liang
Mechanical properties of a porcine aortic valve fixed with a naturally occurring crosslinking agent.
Biomaterials 1999;20(19):1759-72.
1998: Hung-Wen Tsai; Shulan Hsieh; P C Li; Fong-Chung Lai; Y T Yu; Yen Chang
Malignant fibrous histocytoma of the heart presenting as right ventricular outflow tract obstruction: a case report.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 1998;61(8):484-7.
1998: J H Lu; Yen Chang; Hsing-Wen Sung; Y T Chiu; P C Yang; B Hwang
Heparinization on pericardial substitutes can reduce adhesion and epicardial inflammation in the dog.
The Journal of thoracic and cardiovascular surgery 1998;115(5):1111-20.
1998: Chun-Che Shih; Shiau-Ting Lai; Yen Chang
Computed tomography in the determination of surgical emergency for symptomatic abdominal aortic aneurysm.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 1998;61(4):210-5.
1997: Hsing-Wen Sung; CS Hsu; H C Chen; HL Hsu; Yen Chang; J H Lu; P C Yang
Fixation of various porcine arteries with an epoxy compound.
Artificial organs 1997;21(1):50-8.
1996: Hsing-Wen Sung; Yen Chang; Y T Chiu; HL Hsu; C C Shih; J H Lu; P C Yang
Evaluation of an epoxy-fixed biological patch with ionically bound heparin as a pericardial substitute.
Biomaterials 1996;17(17):1693-701.