Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Jean-Pierre Changeux

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Living Beings

Anatomy

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Maouche Kamel; Polette Myriam; Jolly Thomas; Medjber Kahina; Cloëz-Tayarani Isabelle; Changeux Jean-Pierre; Burlet Henriette; Terryn Christine; Coraux Christelle; Zahm Jean-Marie; Birembaut Philippe; Tournier Jean-Marie
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation.
Wiklund Andreas; Granon Sylvie; Faure Philippe; Sundman Eva; Changeux Jean-Pierre; Eriksson Lars I
Object memory in young and aged mice after sevoflurane anaesthesia.
Taly Antoine; Corringer Pierre-Jean; Guedin Denis; Lestage Pierre; Changeux Jean-Pierre
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Jean-Pierre Changeux (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Maouche Kamel; Polette Myriam; Jolly Thomas; Medjber Kahina; Cloëz-Tayarani Isabelle; Changeux Jean-Pierre; Burlet Henriette; Terryn Christine; Coraux Christelle; Zahm Jean-Marie; Birembaut Philippe; Tournier Jean-Marie
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation.
The American journal of pathology 2009;175(5):1868-82.
2009: Wiklund Andreas; Granon Sylvie; Faure Philippe; Sundman Eva; Changeux Jean-Pierre; Eriksson Lars I
Object memory in young and aged mice after sevoflurane anaesthesia.
Neuroreport 2009;20(16):1419-23.
2009: Taly Antoine; Corringer Pierre-Jean; Guedin Denis; Lestage Pierre; Changeux Jean-Pierre
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system.
Nature reviews. Drug discovery 2009;8(9):733-50.
2009: Changeux Jean-Pierre
Nicotinic receptors and nicotine addiction.
Comptes rendus biologies 2009;332(5):421-5.
2009: Grailhe Régis; Cardona Ana; Even Naïla; Seif Isabelle; Changeux Jean-Pierre; Cloëz-Tayarani Isabelle
Regional changes in the cholinergic system in mice lacking monoamine oxidase A.
Brain research bulletin 2009;78(6):283-9.
2009: Lagercrantz Hugo; Changeux Jean-Pierre
The emergence of human consciousness: from fetal to neonatal life.
Pediatric research 2009;65(3):255-60.
2009: Suarez S V; Amadon A; Giacomini E; Wiklund A; Changeux J-P; Le Bihan D; Granon S
Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study.
Psychopharmacology 2009;202(4):599-610.
2009: Bocquet Nicolas; Nury Hugues; Baaden Marc; Le Poupon Chantal; Changeux Jean-Pierre; Delarue Marc; Corringer Pierre-Jean
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation.
Nature 2009;457(7225):111-4.
2008: Maubourguet Nicolas; Lesne Annick; Changeux Jean-Pierre; Maskos Uwe; Faure Philippe
Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration.
PLoS computational biology 2008;4(11):e1000229.
2008: Pons S; Fattore L; Cossu G; Tolu S; Porcu E; McIntosh J M; Changeux J P; Maskos U; Fratta W
Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(47):12318-27.
2008: Wiklund Andreas; Granon Sylvie; Cloëz-Tayarani Isabelle; Faure Philippe; le Sourd Anne-Marie; Sundman Eva; Changeux Jean-Pierre; Eriksson Lars I
Sevoflurane anesthesia alters exploratory and anxiety-like behavior in mice lacking the beta2 nicotinic acetylcholine receptor subunit.
Anesthesiology 2008;109(5):790-8.
2008: Avale Maria Elena; Faure Philippe; Pons Stéphanie; Robledo Patricia; Deltheil Thierry; David Denis J; Gardier Alain M; Maldonado Rafael; Granon Sylvie; Changeux Jean-Pierre; Maskos Uwe
Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(41):15991-6.
2008: Even Naïla; Cardona Ana; Soudant Martine; Corringer Pierre-Jean; Changeux Jean-Pierre; Cloëz-Tayarani Isabelle
Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors.
Neuroreport 2008;19(15):1545-50.
2008: Evrard Alexis; Changeux Jean-Pierre
Abnormal response of dopaminergic neurons to nicotine without perturbation of nicotinic receptors in alphaCGRP knock-out mice.
Brain research 2008;1228():89-96.
2008: Besson Morgane; Suarez Sandra; Cormier Anne; Changeux Jean-Pierre; Granon Sylvie
Chronic nicotine exposure has dissociable behavioural effects on control and beta2-/- mice.
Behavior genetics 2008;38(5):503-14.
2008: Aráoz Rómulo; Herdman Michael; Rippka Rosmarie; Ledreux Aurélie; Molgó Jordi; Changeux Jean-Pierre; Tandeau de Marsac Nicole; Nghiêm Hoàng-Oanh
A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes.
Toxicon : official journal of the International Society on Toxinology 2008;52(1):163-74.
2008: Jackson K J; Martin B R; Changeux J P; Damaj M I
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs.
The Journal of pharmacology and experimental therapeutics 2008;325(1):302-12.
2008: Putz G; Kristufek D; Orr-Urtreger A; Changeux J-P; Huck S; Scholze P
Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes.
Journal of neuroscience research 2008;86(5):972-81.
2008: Changeux Jean-Pierre; Taly Antoine
Nicotinic receptors, allosteric proteins and medicine.
Trends in molecular medicine 2008;14(3):93-102.
2008: Taly Antoine; Changeux Jean-Pierre
Functional organization and conformational dynamics of the nicotinic receptor: a plausible structural interpretation of myasthenic mutations.
Annals of the New York Academy of Sciences 2008;1132():42-52.
2007: Kabbani Nadine; Woll Matthew P; Levenson Robert; Lindstrom Jon M; Changeux Jean-Pierre
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(51):20570-5.
2007: Zanardi Alessio; Ferrari Rosaria; Leo Giuseppina; Maskos Uwe; Changeux Jean-Pierre; Zoli Michele
Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4028-37.
2007: Konstantakaki Maria; Changeux Jean-Pierre; Taly Antoine
Docking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor.
Biochemical and biophysical research communications 2007;359(3):413-8.
2007: Moser N; Mechawar N; Jones I; Gochberg-Sarver A; Orr-Urtreger A; Plomann M; Salas R; Molles B; Marubio L; Roth U; Maskos U; Winzer-Serhan U; Bourgeois J-P; Le Sourd A-M; De Biasi M; Schröder H; Lindstrom J; Maelicke A; Changeux J-P; Wevers A
Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures.
Journal of neurochemistry 2007;102(2):479-92.
2007: Scholze P; Orr-Urtreger A; Changeux J-P; McIntosh J M; Huck S
Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation.
British journal of pharmacology 2007;151(3):414-22.
2007: Besson Morgane; Granon Sylvie; Mameli-Engvall Monica; Cloëz-Tayarani Isabelle; Maubourguet Nicolas; Cormier Anne; Cazala Pierre; David Vincent; Changeux Jean-Pierre; Faure Philippe
Long-term effects of chronic nicotine exposure on brain nicotinic receptors.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8155-60.
2007: Skok M V; Grailhe R; Agenes F; Changeux J-P
The role of nicotinic receptors in B-lymphocyte development and activation.
Life sciences 2007;80(24-25):2334-6.
2007: Cloëz-Tayarani Isabelle; Changeux Jean-Pierre
Nicotine and serotonin in immune regulation and inflammatory processes: a perspective.
Journal of leukocyte biology 2007;81(3):599-606.
2007: Bocquet Nicolas; Prado de Carvalho Lia; Cartaud Jean; Neyton Jacques; Le Poupon Chantal; Taly Antoine; Grutter Thomas; Changeux Jean-Pierre; Corringer Pierre-Jean
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family.
Nature 2007;445(7123):116-9.
2006: Changeux Jean-Pierre
The Ferrier Lecture 1998. The molecular biology of consciousness investigated with genetically modified mice.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006;361(1476):2239-59.
2006: Taly Antoine; Corringer Pierre-Jean; Grutter Thomas; Prado de Carvalho Lia; Karplus Martin; Changeux Jean-Pierre
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16965-70.
2006: Vincent Pierre; Maskos Uwe; Charvet Igor; Bourgeais Laurence; Stoppini Luc; Leresche Nathalie; Changeux Jean-Pierre; Lambert Régis; Meda Paolo; Paupardin-Tritsch Danièle
Live imaging of neural structure and function by fibred fluorescence microscopy.
EMBO reports 2006;7(11):1154-61.
2006: Le Magueresse Corentin; Safiulina Victoria; Changeux Jean-Pierre; Cherubini Enrico
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice.
The Journal of physiology 2006;576(Pt 2):533-46.
2006: Zanetti Lara; de Kerchove D'Exaerde Alban; Zanardi Alessio; Changeux Jean-Pierre; Picciotto Marina R; Zoli Michele
Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum.
Psychopharmacology 2006;187(2):181-8.
2006: Besson M; David V; Suarez S; Cormier A; Cazala P; Changeux J-P; Granon S
Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome.
Psychopharmacology 2006;187(2):189-99.
2006: Villégier Anne-Sophie; Salomon Lucas; Granon Sylvie; Changeux Jean-Pierre; Belluzzi James D; Leslie Frances M; Tassin Jean-Pol
Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(8):1704-13.
2006: Grailhe Regis; Merola Fabienne; Ridard Jacqueline; Couvignou Stephen; Le Poupon Chantal; Changeux Jean-Pierre; Laguitton-Pasquier Helene
Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein.
Chemphyschem : a European journal of chemical physics and physical chemistry 2006;7(7):1442-54.
2006: Mameli-Engvall Monica; Evrard Alexis; Pons Stéphanie; Maskos Uwe; Svensson Torgny H; Changeux Jean-Pierre; Faure Philippe
Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors.
Neuron 2006;50(6):911-21.
2006: Granon Sylvie; Changeux Jean-Pierre
Attention-deficit/hyperactivity disorder: a plausible mouse model?
Acta paediatrica (Oslo, Norway : 1992) 2006;95(6):645-9.
2006: David Vincent; Besson Morgane; Changeux Jean-Pierre; Granon Sylvie; Cazala Pierre
Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors.
Neuropharmacology 2006;50(8):1030-40.
2006: Dehaene Stanislas; Changeux Jean-Pierre; Naccache Lionel; Sackur Jérôme; Sergent Claire
Conscious, preconscious, and subliminal processing: a testable taxonomy.
Trends in cognitive sciences 2006;10(5):204-11.
2006: Sunesen Morten; de Carvalho Lia Prado; Dufresne Virginie; Grailhe Regis; Savatier-Duclert Nathalie; Gibor Gilad; Peretz Asher; Attali Bernard; Changeux Jean-Pierre; Paas Yoav
Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter.
The Journal of biological chemistry 2006;281(21):14875-81.
2006: Corringer Pierre-Jean; Sallette Jérôme; Changeux Jean-Pierre
Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity?
Journal of physiology, Paris 2006;99(2-3):162-71.
2006: Walters Carrie L; Brown Sharon; Changeux Jean-Pierre; Martin Billy; Damaj M Imad
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice.
Psychopharmacology 2006;184(3-4):339-44.
2006: Skok Marina; Grailhe Regis; Agenes Fabien; Changeux Jean-Pierre
The role of nicotinic acetylcholine receptors in lymphocyte development.
Journal of neuroimmunology 2006;171(1-2):86-98.
2006: Gutkin Boris S; Dehaene Stanislas; Changeux Jean-Pierre
A neurocomputational hypothesis for nicotine addiction.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):1106-11.
2006: Molles B E; Maskos U; Pons S; Besson M; Guiard P; Guilloux J-P; Evrard A; Cormier A; Mameli-Engvall M; Cloëz-Tayarani I; Nakatani H; Dufour N; Bemelmans A-P; Mallet J; Cazala P; Gardier A M; David V; Faure P; Granon S; Changeux J-P
Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors.
Journal of molecular neuroscience : MN 2006;30(1-2):105-6.
2006: Grutter Thomas; de Carvalho Lia Prado; Dufresne Virginie; Taly Antoine; Changeux Jean-Pierre
Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel.
Journal of molecular neuroscience : MN 2006;30(1-2):63-4.
2005: Grutter Thomas; de Carvalho Lia Prado; Dufresne Virginie; Taly Antoine; Edelstein Stuart J; Changeux Jean-Pierre
Molecular tuning of fast gating in pentameric ligand-gated ion channels.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18207-12.
2005: Paas Yoav; Gibor Gilad; Grailhe Regis; Savatier-Duclert Nathalie; Dufresne Virginie; Sunesen Morten; de Carvalho Lia Prado; Changeux Jean-Pierre; Attali Bernard
Pore conformations and gating mechanism of a Cys-loop receptor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15877-82.
2005: Gotti Cecilia; Moretti Milena; Zanardi Alessio; Gaimarri Annalisa; Champtiaux Nicolas; Changeux Jean-Pierre; Whiteaker Paul; Marks Michael J; Clementi Francesco; Zoli Michele
Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype alpha3beta2(alpha5 or beta3) enriched in retinocollicular afferents.
Molecular pharmacology 2005;68(4):1162-71.
2005: Mrsic-Flogel Thomas D; Hofer Sonja B; Creutzfeldt Claire; Cloëz-Tayarani Isabelle; Changeux Jean-Pierre; Bonhoeffer Tobias; Hübener Mark
Altered map of visual space in the superior colliculus of mice lacking early retinal waves.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(29):6921-8.
2005: Maskos U; Molles B E; Pons S; Besson M; Guiard B P; Guilloux J-P; Evrard A; Cazala P; Cormier A; Mameli-Engvall M; Dufour N; Cloëz-Tayarani I; Bemelmans A-P; Mallet J; Gardier A M; David V; Faure P; Granon S; Changeux J-P
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.
Nature 2005;436(7047):103-7.
2005: Skok Marina; Grailhe Régis; Changeux Jean-Pierre
Nicotinic receptors regulate B lymphocyte activation and immune response.
European journal of pharmacology 2005;517(3):246-51.
2005: Changeux Jean-Pierre; Edelstein Stuart J
Allosteric mechanisms of signal transduction.
Science (New York, N.Y.) 2005;308(5727):1424-8.
2005: Taly Antoine; Delarue Marc; Grutter Thomas; Nilges Michael; Le Novère Nicolas; Corringer Pierre-Jean; Changeux Jean-Pierre
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism.
Biophysical journal 2005;88(6):3954-65.
2005: Sallette Jérôme; Pons Stéphanie; Devillers-Thiery Anne; Soudant Martine; Prado de Carvalho Lia; Changeux Jean-Pierre; Corringer Pierre Jean
Nicotine upregulates its own receptors through enhanced intracellular maturation.
Neuron 2005;46(4):595-607.
2005: Dehaene Stanislas; Changeux Jean-Pierre
Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness.
PLoS biology 2005;3(5):e141.
2005: Gisiger Thomas; Kerszberg Michel; Changeux Jean-Pierre
Acquisition and performance of delayed-response tasks: a neural network model.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(5):489-506.
2005: Grutter Thomas; Prado de Carvalho Lia; Virginie Dufresne; Taly Antoine; Fischer Markus; Changeux Jean-Pierre
A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels.
Comptes rendus biologies 2005;328(3):223-34.
2005: Cohen Gary; Roux Jean-Christophe; Grailhe Régis; Malcolm Girvan; Changeux Jean-Pierre; Lagercrantz Hugo
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3817-21.
2004: Strochlic Laure; Cartaud Annie; Mejat Alexandre; Grailhe Régis; Schaeffer Laurent; Changeux Jean-Pierre; Cartaud Jean
14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18189-94.
2004: Cormier Anne; Paas Yoav; Zini Roland; Tillement Jean-Paul; Lagrue Gilbert; Changeux Jean-Pierre; Grailhe Régis
Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice.
Molecular pharmacology 2004;66(6):1712-8.
2004: Dauger S; Durand E; Cohen G; Lagercrantz H; Changeux J-P; Gaultier C; Gallego J
Control of breathing in newborn mice lacking the beta-2 nAChR subunit.
Acta physiologica Scandinavica 2004;182(2):205-12.
2004: Pons S; Sallette J; Bourgeois J P; Taly A; Changeux J P; Devillers-Thiéry A
Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha 7-5HT3A receptor.
The European journal of neuroscience 2004;20(8):2022-30.
2004: Maggi Laura; Sola Elisabetta; Minneci Federico; Le Magueresse Corentin; Changeux Jean Pierre; Cherubini Enrico
Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus.
The Journal of physiology 2004;559(Pt 3):863-74.
2004: Schütz Burkhard; Mauer Daniela; Salmon Anne-Marie; Changeux Jean-Pierre; Zimmer Andreas
Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice.
The Journal of comparative neurology 2004;476(1):32-43.
2004: Léna Clément; Popa Daniela; Grailhe Régis; Escourrou Pierre; Changeux Jean-Pierre; Adrien Joëlle
Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(25):5711-8.
2004: Mechawar Naguib; Saghatelyan Armen; Grailhe Régis; Scoriels Linda; Gheusi Gilles; Gabellec Marie-Madeleine; Lledo Pierre-Marie; Changeux Jean-Pierre
Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9822-6.
2004: Cordero-Erausquin Matilde; Pons Stéphanie; Faure Philippe; Changeux Jean-Pierre
Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord.
Pain 2004;109(3):308-18.
2004: Salmon Anne-Marie; Evrard Alexis; Damaj Imad; Changeux Jean-Pierre
Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice.
Neuroscience letters 2004;360(1-2):73-6.
2004: Sallette Jérôme; Bohler Sébastien; Benoit Pierre; Soudant Martine; Pons Stéphanie; Le Novère Nicolas; Changeux Jean-Pierre; Corringer Pierre Jean
An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine.
The Journal of biological chemistry 2004;279(18):18767-75.
2004: Grailhe Régis; de Carvalho Lia Prado; Paas Yoav; Le Poupon Chantal; Soudant Martine; Bregestovski Piotr; Changeux Jean-Pierre; Corringer Pierre-Jean
Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons.
The European journal of neuroscience 2004;19(4):855-62.
2004: Grutter Thomas; Le Novère Nicolas; Changeux Jean-Pierre
Rational understanding of nicotinic receptors drug binding.
Current topics in medicinal chemistry 2004;4(6):645-50.
2004: Champtiaux Nicolas; Changeux Jean-Pierre
Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system.
Progress in brain research 2004;145():235-51.
2003: Grubb Matthew S; Rossi Francesco M; Changeux Jean Pierre; Thompson Ian D
Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor.
Neuron 2003;40(6):1161-72.
2003: Sunesen Morten; Huchet-Dymanus Monique; Christensen Morten O; Changeux Jean-Pierre
Phosphorylation-elicited quaternary changes of GA binding protein in transcriptional activation.
Molecular and cellular biology 2003;23(22):8008-18.
2003: Skok Marina V; Kalashnik Elena N; Koval Ludmila N; Tsetlin Victor I; Utkin Yuriy N; Changeux Jean-Pierre; Grailhe Régis
Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines.
Molecular pharmacology 2003;64(4):885-9.
2003: Devillers-Thiéry A; Bourgeois J P; Pons S; Le Sourd A; Pucci B; Changeux J P
An in vitro study of the sub-cellular distribution of nicotinic receptors.
Biology of the cell / under the auspices of the European Cell Biology Organization 2003;95(6):373-81.
2003: Paas Yoav; Cartaud Jean; Recouvreur Michel; Grailhe Regis; Dufresne Virginie; Pebay-Peyroula Eva; Landau Ehud M; Changeux Jean-Pierre
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11309-14.
2003: Champtiaux Nicolas; Gotti Cecilia; Cordero-Erausquin Matilde; David Denis J; Przybylski Cédric; Léna Clément; Clementi Francesco; Moretti Milena; Rossi Francesco M; Le Novère Nicolas; McIntosh J Michael; Gardier Alain M; Changeux Jean-Pierre
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(21):7820-9.
2003: Granon Sylvie; Faure Philippe; Changeux Jean-Pierre
Executive and social behaviors under nicotinic receptor regulation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9596-601.
2003: Dehaene Stanislas; Sergent Claire; Changeux Jean-Pierre
A neuronal network model linking subjective reports and objective physiological data during conscious perception.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8520-5.
2003: Sunesen Morten; Changeux Jean-Pierre
Transcription in neuromuscular junction formation: who turns on whom?
Journal of neurocytology 2003;32(5-8):677-84.
2003: Han Zhi-Yan; Zoli Michele; Cardona Ana; Bourgeois Jean-Pierre; Changeux Jean-Pierre; Le Novère Nicolas
Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta.
The Journal of comparative neurology 2003;461(1):49-60.
2003: Grutter Thomas; Prado de Carvalho Lia; Le Novère Nicolas; Corringer Pierre Jean; Edelstein Stuart; Changeux Jean-Pierre
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors.
The EMBO journal 2003;22(9):1990-2003.
2003: Marubio L M; Gardier A M; Durier S; David D; Klink R; Arroyo-Jimenez M M; McIntosh J M; Rossi F; Champtiaux N; Zoli M; Changeux J-P
Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors.
The European journal of neuroscience 2003;17(7):1329-37.
2003: Maggi Laura; Le Magueresse Corentin; Changeux Jean-Pierre; Cherubini Enrico
Nicotine activates immature "silent" connections in the developing hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):2059-64.
2002: Le Novère Nicolas; Corringer Pierre-Jean; Changeux Jean-Pierre
The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences.
Journal of neurobiology 2002;53(4):447-56.
2002: de Kerchove D'Exaerde Alban; Cartaud Jean; Ravel-Chapuis Aymeric; Seroz Thierry; Pasteau Fabien; Angus Lindsay M; Jasmin Bernard J; Changeux Jean-Pierre; Schaeffer Laurent
Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression.
EMBO reports 2002;3(11):1075-81.
2002: Marchand Sophie; Devillers-Thiéry Anne; Pons Stéphanie; Changeux Jean-Pierre; Cartaud Jean
Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(20):8891-901.
2002: Cohen Gary; Han Zhi-Yan; Grailhe Régis; Gallego Jorge; Gaultier Claude; Changeux Jean-Pierre; Lagercrantz Hugo
beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13272-7.
2002: Martinez Karen L; Gohon Yann; Corringer Pierre-Jean; Tribet Christophe; Mérola Fabienne; Changeux Jean-Pierre; Popot Jean-Luc
Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints.
FEBS letters 2002;528(1-3):251-6.
2002: Champtiaux N; Changeux J P
Knock-out and knock-in mice to investigate the role of nicotinic receptors in the central nervous system.
Current drug targets. CNS and neurological disorders 2002;1(4):319-30.
2002: Ferrari R; Le Novère N; Picciotto M R; Changeux J P; Zoli M
Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections.
The European journal of neuroscience 2002;15(11):1810-8.
2002: Shoaib M; Gommans J; Morley A; Stolerman I P; Grailhe R; Changeux J-P
The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion.
Neuropharmacology 2002;42(4):530-9.
2002: Fruchart-Gaillard Carole; Gilquin Bernard; Antil-Delbeke Stephanie; Le Novère Nicolas; Tamiya Toru; Corringer Pierre-Jean; Changeux Jean-Pierre; Ménez André; Servent Denis
Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3216-21.
2002: Le Novère Nicolas; Grutter Thomas; Changeux Jean-Pierre
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3210-5.
2002: Laudenbach Vincent; Medja Fadia; Zoli Michele; Rossi Francesco M; Evrard Philippe; Changeux Jean-Pierre; Gressens Pierre
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):423-5.
2002: Champtiaux Nicolas; Han Zhi-Yan; Bessis Alain; Rossi Francesco Mattia; Zoli Michele; Marubio Lisa; McIntosh J Michael; Changeux Jean-Pierre
Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(4):1208-17.
2002: Fischer Markus; Haase Ilka; Feicht Richard; Richter Gerald; Gerhardt Stefan; Changeux Jean-Pierre; Huber Robert; Bacher Adelbert
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
European journal of biochemistry / FEBS 2002;269(2):519-26.
2001: Le Novère N; Changeux J P
The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1412):1121-30.
2001: Grutter T; Changeux J P
Nicotinic receptors in wonderland.
Trends in biochemical sciences 2001;26(8):459-63.
2001: Schaeffer L; de Kerchove d'Exaerde A; Changeux J P
Targeting transcription to the neuromuscular synapse.
Neuron 2001;31(1):15-22.
2001: Changeux J; Edelstein S J
Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors.
Current opinion in neurobiology 2001;11(3):369-77.
2001: Lukas R J; Lucero L; Buisson B; Galzi J L; Puchacz E; Fryer J D; Changeux J P; Bertrand D
Neurotoxicity of channel mutations in heterologously expressed alpha7-nicotinic acetylcholine receptors.
The European journal of neuroscience 2001;13(10):1849-60.
2001: Rossi F M; Pizzorusso T; Porciatti V; Marubio L M; Maffei L; Changeux J P
Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6453-8.
2001: Zachariou V; Caldarone B J; Weathers-Lowin A; George T P; Elsworth J D; Roth R H; Changeux J P; Picciotto M R
Nicotine receptor inactivation decreases sensitivity to cocaine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(5):576-89.
2001: Changeux J P
Cajal on neurons, molecules, and consciousness.
Annals of the New York Academy of Sciences 2001;929():147-51.
2001: Salmon A M; Damaj M I; Marubio L M; Epping-Jordan M P; Merlo-Pich E; Changeux J P
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice.
Nature neuroscience 2001;4(4):357-8.
2001: Fischer M; Corringer P J; Schott K; Bacher A; Changeux J P
A method for soluble overexpression of the alpha7 nicotinic acetylcholine receptor extracellular domain.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3567-70.
2001: Klink R; de Kerchove d'Exaerde A; Zoli M; Changeux J P
Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(5):1452-63.
2001: Bohler S; Gay S; Bertrand S; Corringer P J; Edelstein S J; Changeux J P; Bertrand D
Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit.
Biochemistry 2001;40(7):2066-74.
2001: Cordero-Erausquin M; Changeux J P
Tonic nicotinic modulation of serotoninergic transmission in the spinal cord.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2803-7.
2001: Altiok N; Changeux J P
Electrical activity regulates AChR gene expression via JNK, PKCzeta and Sp1 in skeletal chick muscle.
FEBS letters 2001;487(3):333-8.
2001: Grady S R; Meinerz N M; Cao J; Reynolds A M; Picciotto M R; Changeux J P; McIntosh J M; Marks M J; Collins A C
Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum.
Journal of neurochemistry 2001;76(1):258-68.
2001: Le Novère N; Changeux J P
LGICdb: the ligand-gated ion channel database.
Nucleic acids research 2001;29(1):294-5.
2000: Marks M J; Stitzel J A; Grady S R; Picciotto M R; Changeux J P; Collins A C
Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype.
Neuropharmacology 2000;39(13):2632-45.
2000: Han Z Y; Le Novère N; Zoli M; Hill J A; Champtiaux N; Changeux J P
Localization of nAChR subunit mRNAs in the brain of Macaca mulatta.
The European journal of neuroscience 2000;12(10):3664-74.
2000: Antil-Delbeke S; Gaillard C; Tamiya T; Corringer P J; Changeux J P; Servent D; Ménez A
Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor.
The Journal of biological chemistry 2000;275(38):29594-601.
2000: Rogner U C; Spyropoulos D D; Le Novère N; Changeux J P; Avner P
Control of neurulation by the nucleosome assembly protein-1-like 2.
Nature genetics 2000;25(4):431-5.
2000: Tsuneki H; Klink R; Léna C; Korn H; Changeux J P
Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.
The European journal of neuroscience 2000;12(7):2475-85.
2000: Martinez K L; Corringer P J; Edelstein S J; Changeux J P; Mérola F
Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy.
Biochemistry 2000;39(23):6979-90.
2000: Cordero-Erausquin M; Marubio L M; Klink R; Changeux J P
Nicotinic receptor function: new perspectives from knockout mice.
Trends in pharmacological sciences 2000;21(6):211-7.
2000: Gisiger T; Dehaene S; Changeux J P
Computational models of association cortex.
Current opinion in neurobiology 2000;10(2):250-9.
2000: Servent D; Antil-Delbeke S; Gaillard C; Corringer P J; Changeux J P; Ménez A
Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors.
European journal of pharmacology 2000;393(1-3):197-204.
2000: Whiteaker P; Marks M J; Grady S R; Lu Y; Picciotto M R; Changeux J P; Collins A C
Pharmacological and null mutation approaches reveal nicotinic receptor diversity.
European journal of pharmacology 2000;393(1-3):123-35.
2000: Marubio L M; Changeux J
Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function.
European journal of pharmacology 2000;393(1-3):113-21.
2000: Nghiêm H O; Bettendorff L; Changeux J P
Specific phosphorylation of Torpedo 43K rapsyn by endogenous kinase(s) with thiamine triphosphate as the phosphate donor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(3):543-54.
2000: Paas Y; Devillers-Thiéry A; Teichberg V I; Changeux J P; Eisenstein M
How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors.
Trends in pharmacological sciences 2000;21(3):87-92.
2000: Changeux J P; Dehaene S
Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2000;35(2-3):179-87.
2000: Paas-Rozner M; Dayan M; Paas Y; Changeux J P; Wirguin I; Sela M; Mozes E
Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2168-73.
2000: Dehaene S; Changeux J P
Reward-dependent learning in neuronal networks for planning and decision making.
Progress in brain research 2000;126():217-29.
2000: Corringer P J; Le Novère N; Changeux J P
Nicotinic receptors at the amino acid level.
Annual review of pharmacology and toxicology 2000;40():431-58.
1999: Epping-Jordan M P; Picciotto M R; Changeux J P; Pich E M
Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice.
Psychopharmacology 1999;147(1):25-6.
1999: Léna C; de Kerchove D'Exaerde A; Cordero-Erausquin M; Le Novère N; del Mar Arroyo-Jimenez M; Changeux J P
Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12126-31.
1999: le Novère N; Zoli M; Léna C; Ferrari R; Picciotto M R; Merlo-Pich E; Changeux J P
Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion.
Neuroreport 1999;10(12):2497-501.
1999: Arroyo-Jim nez M M; Bourgeois J P; Marubio L M; Le Sourd A M; Ottersen O P; Rinvik E; Fairén A; Changeux J P
Ultrastructural localization of the alpha4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(15):6475-87.
1999: Lukas R J; Changeux J P; Le Novère N; Albuquerque E X; Balfour D J; Berg D K; Bertrand D; Chiappinelli V A; Clarke P B; Collins A C; Dani J A; Grady S R; Kellar K J; Lindstrom J M; Marks M J; Quik M; Taylor P W; Wonnacott S
International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.
Pharmacological reviews 1999;51(2):397-401.
1999: Le Novère N; Corringer P J; Changeux J P
Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation.
Biophysical journal 1999;76(5):2329-45.
1999: Marks M J; Whiteaker P; Calcaterra J; Stitzel J A; Bullock A E; Grady S R; Picciotto M R; Changeux J P; Collins A C
Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit.
The Journal of pharmacology and experimental therapeutics 1999;289(2):1090-103.
1999: Léna C; Changeux J P
The role of beta 2-subunit-containing nicotinic acetylcholine receptors in the brain explored with a mutant mouse.
Annals of the New York Academy of Sciences 1999;868():611-6.
1999: Marubio L M; del Mar Arroyo-Jimenez M; Cordero-Erausquin M; Léna C; Le Novère N; de Kerchove d'Exaerde A; Huchet M; Damaj M I; Changeux J P
Reduced antinociception in mice lacking neuronal nicotinic receptor subunits.
Nature 1999;398(6730):805-10.
1999: Corringer P J; Bertrand S; Galzi J L; Devillers-Thiéry A; Changeux J P; Bertrand D
Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor.
Neuron 1999;22(4):831-43.
1999: Salmon A M; Damaj I; Sekine S; Picciotto M R; Marubio L; Changeux J P
Modulation of morphine analgesia in alphaCGRP mutant mice.
Neuroreport 1999;10(4):849-54.
1999: Gramolini A O; Angus L M; Schaeffer L; Burton E A; Tinsley J M; Davies K E; Changeux J P; Jasmin B J
Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3223-7.
1999: Zoli M; Picciotto M R; Ferrari R; Cocchi D; Changeux J P
Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors.
The EMBO journal 1999;18(5):1235-44.
1999: Le Novère N; Changeux J P
The Ligand Gated Ion Channel Database.
Nucleic acids research 1999;27(1):340-2.
1999: Picciotto M R; Zoli M; Changeux J P
Use of knock-out mice to determine the molecular basis for the actions of nicotine.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 1999;1 Suppl 2():S121-5; discussion S139-40.
1999: Bertrand D; Changeux J P
Nicotinic receptor: a prototype of allosteric ligand-gated ion channels and its possible implications in epilepsy.
Advances in neurology 1999;79():171-88.
1999: Corringer P J; Bertrand S; Galzi J L; Devillers-Thiéry A; Changeux J P; Bertrand D
Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels.
Novartis Foundation symposium 1999;225():215-24; discussion 224-30.
1998: Changeux J P; Edelstein S J
Allosteric receptors after 30 years.
Neuron 1998;21(5):959-80.
1998: Dehaene S; Kerszberg M; Changeux J P
A neuronal model of a global workspace in effortful cognitive tasks.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14529-34.
1998: Lu Y; Grady S; Marks M J; Picciotto M; Changeux J P; Collins A C
Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes.
The Journal of pharmacology and experimental therapeutics 1998;287(2):648-57.
1998: Kerszberg M; Changeux J P
A simple molecular model of neurulation.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(9):758-70.
1998: Hoedemaekers A; Bessereau J L; Graus Y; Guyon T; Changeux J P; Berrih-Aknin S; van Breda Vriesman P; De Baets M H
Role of the target organ in determining susceptibility to experimental autoimmune myasthenia gravis.
Journal of neuroimmunology 1998;89(1-2):131-41.
1998: Watanabe H; Zoli M; Changeux J P
Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene.
The European journal of neuroscience 1998;10(7):2244-53.
1998: Salmon A M; Bruand C; Cardona A; Changeux J P; Berrih-Aknin S
An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis.
The Journal of clinical investigation 1998;101(11):2340-50.
1998: Zoli M; Léna C; Picciotto M R; Changeux J P
Identification of four classes of brain nicotinic receptors using beta2 mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4461-72.
1998: Schaeffer L; Duclert N; Huchet-Dymanus M; Changeux J P
Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor.
The EMBO journal 1998;17(11):3078-90.
1998: Hoedemaekers A; Bessereau J L; Graus Y; Guyon T; Changeux J P; Berrih-Aknin S; Van Breda Vriesman P; De Baets M
Differential susceptibility of young and old rat neuromuscular junctions to antibody-mediated AChR degradation in experimental autoimmune myasthenia gravis.
Annals of the New York Academy of Sciences 1998;841():550-4.
1998: Changeux J P; Bertrand D; Corringer P J; Dehaene S; Edelstein S; Léna C; Le Novère N; Marubio L; Picciotto M; Zoli M
Brain nicotinic receptors: structure and regulation, role in learning and reinforcement.
Brain research. Brain research reviews 1998;26(2-3):198-216.
1998: Bessereau J L; Laudenbach V; Le Poupon C; Changeux J P
Nonmyogenic factors bind nicotinic acetylcholine receptor promoter elements required for response to denervation.
The Journal of biological chemistry 1998;273(21):12786-93.
1998: Servent D; Thanh H L; Antil S; Bertrand D; Corringer P J; Changeux J P; Ménez A
Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors.
Journal of physiology, Paris 1998;92(2):107-11.
1998: Léna C; Changeux J P
Allosteric nicotinic receptors, human pathologies.
Journal of physiology, Paris 1998;92(2):63-74.
1998: Changeux J P; Dehaene S
Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1998;321(2-3):241-7.
1998: Krause R M; Buisson B; Bertrand S; Corringer P J; Galzi J L; Changeux J P; Bertrand D
Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor.
Molecular pharmacology 1998;53(2):283-94.
1998: Picciotto M R; Zoli M; Rimondini R; Léna C; Marubio L M; Pich E M; Fuxe K; Changeux J P
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
Nature 1998;391(6663):173-7.
1998: Corringer P J; Bertrand S; Bohler S; Edelstein S J; Changeux J P; Bertrand D
Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(2):648-57.
1998: Changeux J P
[Reflections of a neurobiologist on the origin of ethics]
Comptes rendus des séances de la Société de biologie et de ses filiales 1998;192(6):1041-9.
1998: Edelstein S J; Changeux J P
Allosteric transitions of the acetylcholine receptor.
Advances in protein chemistry 1998;51():121-84.
1997: Edelstein S J; Schaad O; Changeux J P
Myasthenic nicotinic receptor mutant interpreted in terms of the allosteric model.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1997;320(12):953-61.
1997: Beeri R; Le Novère N; Mervis R; Huberman T; Grauer E; Changeux J P; Soreq H
Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice.
Journal of neurochemistry 1997;69(6):2441-51.
1997: Bertrand S; Devillers-Thiéry A; Palma E; Buisson B; Edelstein S J; Corringer P J; Changeux J P; Bertrand D
Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants.
Neuroreport 1997;8(16):3591-6.
1997: Edelstein S J; Schaad O; Changeux J P
Single binding versus single channel recordings: a new approach to study ionotropic receptors.
Biochemistry 1997;36(45):13755-60.
1997: Dehaene S; Changeux J P
A hierarchical neuronal network for planning behavior.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):13293-8.
1997: Léna C; Changeux J P
Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders.
Current opinion in neurobiology 1997;7(5):674-82.
1997: Picciotto M R; Zoli M; Zachariou V; Changeux J P
Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine.
Biochemical Society transactions 1997;25(3):824-9.
1997: Changeux J P
Variation and selection in neural function.
Trends in neurosciences 1997;20(7):291-3.
1997: Bessis A; Champtiaux N; Chatelin L; Changeux J P
The neuron-restrictive silencer element: a dual enhancer/silencer crucial for patterned expression of a nicotinic receptor gene in the brain.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5906-11.
1997: Altiok N; Altiok S; Changeux J P
Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity.
The EMBO journal 1997;16(4):717-25.
1997: Léna C; Changeux J P
Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(2):576-85.
1996: Changeux J P
Molecular mechanisms of synaptic transmission and its regulation: application to models of cognitive functions.
NeuroImage 1996;4(3 Pt 2):S7-11.
1996: Edelstein S J; Changeux J P
Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors.
Experientia 1996;52(12):1083-90.
1996: Edelstein S J; Schaad O; Henry E; Bertrand D; Changeux J P
A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions.
Biological cybernetics 1996;75(5):361-79.
1996: Le Novère N; Zoli M; Changeux J P
Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain.
The European journal of neuroscience 1996;8(11):2428-39.
1996: Galzi J L; Bertrand S; Corringer P J; Changeux J P; Bertrand D
Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor.
The EMBO journal 1996;15(21):5824-32.
1996: Yu D; Zhang L; Eiselé J L; Bertrand D; Changeux J P; Weight F F
Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor.
Molecular pharmacology 1996;50(4):1010-6.
1996: Milton N G; Bessis A; Changeux J P; Latchman D S
Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors.
The Biochemical journal 1996;317 ( Pt 2)():419-23.
1996: Duclert A; Savatier N; Schaeffer L; Changeux J P
Identification of an element crucial for the sub-synaptic expression of the acetylcholine receptor epsilon-subunit gene.
The Journal of biological chemistry 1996;271(29):17433-8.
1996: Paas Y; Devillers-Thiéry A; Changeux J P; Medevielle F; Teichberg V I
Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor.
The EMBO journal 1996;15(7):1548-56.
1996: Galzi J L; Edelstein S J; Changeux J
The multiple phenotypes of allosteric receptor mutants.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1853-8.
1996: Changeux J P; Bessis A; Bourgeois J P; Corringer P J; Devillers-Thiery A; Eiselé J L; Kerszberg M; Léna C; Le Novère N; Picciotto M; Zoli M
Nicotinic receptors and brain plasticity.
Cold Spring Harbor symposia on quantitative biology 1996;61():343-62.
1995: Bessis A; Salmon A M; Zoli M; Le Novère N; Picciotto M; Changeux J P
Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice.
Neuroscience 1995;69(3):807-19.
1995: Dehaene S; Changeux J P
Neuronal models of prefrontal cortical functions.
Annals of the New York Academy of Sciences 1995;769():305-19.
1995: Koike S; Schaeffer L; Changeux J P
Identification of a DNA element determining synaptic expression of the mouse acetylcholine receptor delta-subunit gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10624-8.
1995: Altiok N; Bessereau J L; Changeux J P
ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate.
The EMBO journal 1995;14(17):4258-66.
1995: Antony C; Huchet M; Changeux J P; Cartaud J
Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle.
The Journal of cell biology 1995;130(4):959-68.
1995: Legay C; Huchet M; Massoulié J; Changeux J P
Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization.
The European journal of neuroscience 1995;7(8):1803-9.
1995: Milton N G; Bessis A; Changeux J P; Latchman D S
The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c.
The Journal of biological chemistry 1995;270(25):15143-7.
1995: Galzi J L; Changeux J P
Neuronal nicotinic receptors: molecular organization and regulations.
Neuropharmacology 1995;34(6):563-82.
1995: Corringer P J; Galzi J L; Eiselé J L; Bertrand S; Changeux J P; Bertrand D
Identification of a new component of the agonist binding site of the nicotinic alpha 7 homooligomeric receptor.
The Journal of biological chemistry 1995;270(20):11749-52.
1995: Granon S; Poucet B; Thinus-Blanc C; Changeux J P; Vidal C
Nicotinic and muscarinic receptors in the rat prefrontal cortex: differential roles in working memory, response selection and effortful processing.
Psychopharmacology 1995;119(2):139-44.
1995: Li X M; Zoli M; Finnman U B; Le Novère N; Changeux J P; Fuxe K
A single (-)-nicotine injection causes change with a time delay in the affinity of striatal D2 receptors for antagonist, but not for agonist, nor in the D2 receptor mRNA levels in the rat substantia nigra.
Brain research 1995;679(1):157-67.
1995: Changeux J P
Thudichum Medal Lecture. The acetylcholine receptor: a model for allosteric membrane proteins.
Biochemical Society transactions 1995;23(2):195-205.
1995: Duclert A; Changeux J P
Acetylcholine receptor gene expression at the developing neuromuscular junction.
Physiological reviews 1995;75(2):339-68.
1995: Zoli M; Le Novère N; Hill J A; Changeux J P
Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 1):1912-39.
1995: Picciotto M R; Zoli M; Léna C; Bessis A; Lallemand Y; Le Novère N; Vincent P; Pich E M; Brûlet P; Changeux J P
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain.
Nature 1995;374(6517):65-7.
1995: Jasmin B J; Antony C; Changeux J P; Cartaud J
Nerve-dependent plasticity of the Golgi complex in skeletal muscle fibres: compartmentalization within the subneural sarcoplasm.
The European journal of neuroscience 1995;7(3):470-9.
1995: Le Novère N; Changeux J P
Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells.
Journal of molecular evolution 1995;40(2):155-72.
1995: Cartaud A; Jasmin B J; Changeux J P; Cartaud J
Direct involvement of a lamin-B-related (54 kDa) protein in the association of intermediate filaments with the postsynaptic membrane of the Torpedo marmorata electrocyte.
Journal of cell science 1995;108 ( Pt 1)():153-60.
1994: Kerszberg M; Changeux J P
Partners make patterns in morphogenesis.
Current biology : CB 1994;4(11):1046-7.
1994: Granon S; Vidal C; Thinus-Blanc C; Changeux J P; Poucet B
Working memory, response selection, and effortful processing in rats with medial prefrontal lesions.
Behavioral neuroscience 1994;108(5):883-91.
1994: Changeux J P; Edelstein S J
On allosteric mechanisms and acetylcholine receptors.
Trends in biochemical sciences 1994;19(10):399-400.
1994: Changeux J P; Andersen P; Berridge M J; Blakemore C; Bliss T; Gamero A F; Freund T; Grantyn R; Grillner S; Hepp K
European brain research.
Nature 1994;369(6482):601.
1994: Kerszberg M; Changeux J P
A model for reading morphogenetic gradients: autocatalysis and competition at the gene level.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5823-7.
1994: Mendelzon D; Changeux J P; Nghiêm H O
Phosphorylation of myogenin in chick myotubes: regulation by electrical activity and by protein kinase C. Implications for acetylcholine receptor gene expression.
Biochemistry 1994;33(9):2568-75.
1994: Bessereau J L; Stratford-Perricaudet L D; Piette J; Le Poupon C; Changeux J P
In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1304-8.
1993: Eiselé J L; Bertrand S; Galzi J L; Devillers-Thiéry A; Changeux J P; Bertrand D
Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities.
Nature 1993;366(6454):479-83.
1993: Changeux J P
[The chemistry of cerebral communications]
Bulletin de l'Académie nationale de médecine 1993;177(9):1573-85.
1993: Changeux J P
Chemical signaling in the brain.
Scientific American 1993;269(5):58-62.
1993: Venkatasubramanian K; Audhya T; Goldstein G; Revah F; Mulle C; Pinset C; Changeux J P; Quik M; Babu U
Notice of retraction.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10409.
1993: Devillers-Thiéry A; Galzi J L; Eiselé J L; Bertrand S; Bertrand D; Changeux J P
Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels.
The Journal of membrane biology 1993;136(2):97-112.
1993: Quik M; Cook R G; Revah F; Changeux J P; Patrick J
Presence of alpha-cobratoxin and phospholipase A2 activity in thymopoietin preparations.
Molecular pharmacology 1993;44(3):678-9.
1993: Changeux J P
Allosteric proteins: from regulatory enzymes to receptors--personal recollections.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(9):625-34.
1993: Vidal C; Changeux J P
Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro.
Neuroscience 1993;56(1):23-32.
1993: Benoit P; Changeux J P
Voltage dependencies of the effects of chlorpromazine on the nicotinic receptor channel from mouse muscle cell line So18.
Neuroscience letters 1993;160(1):81-4.
1993: Bertrand D; Galzi J L; Devillers-Thiéry A; Bertrand S; Changeux J P
Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):6971-5.
1993: Bertrand D; Galzi J L; Devillers-Thiéry A; Bertrand S; Changeux J P
Stratification of the channel domain in neurotransmitter receptors.
Current opinion in cell biology 1993;5(4):688-93.
1993: Aslanian D; Grof P; Galzi J L; Changeux J P
A Raman spectroscopic study of acetylcholine receptor-rich membranes from Torpedo marmorata. Interaction of the receptor with carbamylcholine and (+)-tubocurarine.
Biochimica et biophysica acta 1993;1148(2):291-302.
1993: Léna C; Changeux J P; Mulle C
Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2680-8.
1993: Bessis A; Savatier N; Devillers-Thiéry A; Bejanin S; Changeux J P
Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene.
Nucleic acids research 1993;21(9):2185-92.
1993: Piette J; Huchet M; Houzelstein D; Changeux J P
Compartmentalized expression of the alpha- and gamma-subunits of the acetylcholine receptor in recently fused myofibers.
Developmental biology 1993;157(1):205-13.
1993: Léna C; Changeux J P
Allosteric modulations of the nicotinic acetylcholine receptor.
Trends in neurosciences 1993;16(5):181-6.
1993: Duclert A; Savatier N; Changeux J P
An 83-nucleotide promoter of the acetylcholine receptor epsilon-subunit gene confers preferential synaptic expression in mouse muscle.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):3043-7.
1993: Hill J A; Zoli M; Bourgeois J P; Changeux J P
Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(4):1551-68.
1993: Daubas P; Salmon A M; Zoli M; Geoffroy B; Devillers-Thiéry A; Bessis A; Médevielle F; Changeux J P
Chicken neuronal acetylcholine receptor alpha 2-subunit gene exhibits neuron-specific expression in the brain and spinal cord of transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2237-41.
1993: Cartaud J; Changeux J P
Post-transcriptional compartmentalization of acetylcholine receptor biosynthesis in the subneural domain of muscle and electrocyte junctions.
The European journal of neuroscience 1993;5(3):191-202.
1993: Bessereau J L; Mendelzon D; LePoupon C; Fiszman M; Changeux J P; Piette J
Muscle-specific expression of the acetylcholine receptor alpha-subunit gene requires both positive and negative interactions between myogenic factors, Sp1 and GBF factors.
The EMBO journal 1993;12(2):443-9.
1992: Salmon A M; Changeux J P
Regulation of an acetylcholine receptor LacZ transgene by muscle innervation.
Neuroreport 1992;3(11):973-6.
1992: Changeux J P; Galzi J L; Devillers-Thiéry A; Bertrand D
The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis.
Quarterly reviews of biophysics 1992;25(4):395-432.
1992: Devillers-Thiéry A; Galzi J L; Bertrand S; Changeux J P; Bertrand D
Stratified organization of the nicotinic acetylcholine receptor channel.
Neuroreport 1992;3(11):1001-4.
1992: Galzi J L; Devillers-Thiéry A; Hussy N; Bertrand S; Changeux J P; Bertrand D
Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.
Nature 1992;359(6395):500-5.
1992: Epstein H F; Fischman D A; Bader D; Changeux J P; Buckhold K; Ordahl C P; Hoffman E; Kedes L H; Konieczny S; Leinwand L A
Myoblast therapy.
Science (New York, N.Y.) 1992;257(5071):738.
1992: Changeux J P; Devillers-Thiéry A; Galzi J L; Bertrand D
New mutants to explore nicotinic receptor functions.
Trends in pharmacological sciences 1992;13(8):299-301.
1992: Cartaud A; Ludosky M A; Tomé F M; Collin H; Stetzkowski-Marden F; Khurana T S; Kunkel L M; Fardeau M; Changeux J P; Cartaud J
Localization of dystrophin and dystrophin-related protein at the electromotor synapse and neuromuscular junction in Torpedo marmorata.
Neuroscience 1992;48(4):995-1003.
1992: Chatrenet B; Kotzba-Hibert F; Mulle C; Changeux J P; Goeldner M P; Hirth C
Photoactivatable agonist of the nicotinic acetylcholine receptor: potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor.
Molecular pharmacology 1992;41(6):1100-6.
1992: Changeux J P; Duclert A; Sekine S
Calcitonin gene-related peptides and neuromuscular interactions.
Annals of the New York Academy of Sciences 1992;657():361-78.
1992: Mulle C; Léna C; Changeux J P
Potentiation of nicotinic receptor response by external calcium in rat central neurons.
Neuron 1992;8(5):937-45.
1992: Piette J; Huchet M; Duclert A; Fujisawa-Sehara A; Changeux J P
Localization of mRNAs coding for CMD1, myogenin and the alpha-subunit of the acetylcholine receptor during skeletal muscle development in the chicken.
Mechanisms of development 1992;37(1-2):95-106.
1992: Bertrand D; Devillers-Thiéry A; Revah F; Galzi J L; Hussy N; Mulle C; Bertrand S; Ballivet M; Changeux J P
Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1261-5.
1992: Mulle C; Choquet D; Korn H; Changeux J P
Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation.
Neuron 1992;8(1):135-43.
1992: Changeux J P
Functional organisation of the nicotinic acetylcholine receptor.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;314(9 Suppl):89-94.
1992: Changeux J P; Devillers-Thiéry A; Galzi J L; Revah F
The acetylcholine receptor: a model of an allosteric membrane protein mediating intercellular communication.
Ciba Foundation symposium 1992;164():66-89; discussion 87-97.
1991: Laufer R; Klarsfeld A; Changeux J P
Phorbol esters inhibit the activity of the chicken acetylcholine receptor alpha-subunit gene promoter. Role of myogenic regulators.
European journal of biochemistry / FEBS 1991;202(3):813-8.
1991: Galzi J L; Bertrand D; Devillers-Thiéry A; Revah F; Bertrand S; Changeux J P
Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis.
FEBS letters 1991;294(3):198-202.
1991: Nghi:em H O; Hill J; Changeux J P
Developmental changes in the subcellular distribution of the 43K (v1) polypeptides in Torpedo marmorata electrocyte: support for a role in acetylcholine receptor stabilization.
Development (Cambridge, England) 1991;113(4):1059-67.
1991: Négrerie M; Aslanian D; Bouet F; Ménez A; Nghiêm H O; Changeux J P
Interaction of modified neurotoxins from Naja nigricollis with the nicotinic acetylcholine receptor from Torpedo marmorata. A Raman spectroscopy study.
FEBS letters 1991;292(1-2):249-53.
1991: Revah F; Bertrand D; Galzi J L; Devillers-Thiéry A; Mulle C; Hussy N; Bertrand S; Ballivet M; Changeux J P
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor.
Nature 1991;353(6347):846-9.
1991: Pinset C; Mulle C; Benoit P; Changeux J P; Chelly J; Gros F; Montarras D
Functional adult acetylcholine receptor develops independently of motor innervation in Sol 8 mouse muscle cell line.
The EMBO journal 1991;10(9):2411-8.
1991: Mulle C; Vidal C; Benoit P; Changeux J P
Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(8):2588-97.
1991: Galzi J L; Revah F; Bouet F; Ménez A; Goeldner M; Hirth C; Changeux J P
Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):5051-5.
1991: Hill J A; Nghiêm H O; Changeux J P
Serine-specific phosphorylation of nicotinic receptor associated 43K protein.
Biochemistry 1991;30(22):5579-85.
1991: Changeux J P
Compartmentalized transcription of acetylcholine receptor genes during motor endplate epigenesis.
The New biologist 1991;3(5):413-29.
1991: Klarsfeld A; Bessereau J L; Salmon A M; Triller A; Babinet C; Changeux J P
An acetylcholine receptor alpha-subunit promoter conferring preferential synaptic expression in muscle of transgenic mice.
The EMBO journal 1991;10(3):625-32.
1991: Villar M J; Roa M; Huchet M; Changeux J P; Valentino K L; Hökfelt T
Occurrence of neuropeptide K-like immunoreactivity in ventral horn cells of the chicken spinal cord during development.
Brain research 1991;541(1):149-53.
1991: Dehaene S; Changeux J P
The Wisconsin Card Sorting Test: theoretical analysis and modeling in a neuronal network.
Cerebral cortex (New York, N.Y. : 1991) 1991;1(1):62-79.
1991: Duclert A; Piette J; Changeux J P
Influence of innervation of myogenic factors and acetylcholine receptor alpha-subunit mRNAs.
Neuroreport 1991;2(1):25-8.
1991: Galzi J L; Revah F; Bessis A; Changeux J P
Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain.
Annual review of pharmacology and toxicology 1991;31():37-72.
1991: Jasmin B J; Changeux J P; Cartaud J
Organization and dynamics of microtubules in Torpedo marmorata electrocyte: selective association with specialized domains of the postsynaptic membrane.
Neuroscience 1991;43(1):151-62.
1991: Roa M; Changeux J P
Characterization and developmental evolution of a high-affinity binding site for calcitonin gene-related peptide on chick skeletal muscle membrane.
Neuroscience 1991;41(2-3):563-70.
1990: Changeux J P
The TiPS lecture. The nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels.
Trends in pharmacological sciences 1990;11(12):485-92.
1990: Daubas P; Devillers-Thiéry A; Geoffroy B; Martinez S; Bessis A; Changeux J P
Differential expression of the neuronal acetylcholine receptor alpha 2 subunit gene during chick brain development.
Neuron 1990;5(1):49-60.
1990: Galzi J L; Revah F; Black D; Goeldner M; Hirth C; Changeux J P
Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites.
The Journal of biological chemistry 1990;265(18):10430-7.
1990: Revah F; Galzi J L; Giraudat J; Haumont P Y; Lederer F; Changeux J P
The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4675-9.
1990: Piette J; Bessereau J L; Huchet M; Changeux J P
Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor alpha-subunit gene.
Nature 1990;345(6273):353-5.
1990: Bessis A; Simon-Chazottes D; Devillers-Thiéry A; Guénet J L; Changeux J P
Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor.
FEBS letters 1990;264(1):48-52.
1990: Jasmin B J; Cartaud A; Ludosky M A; Changeux J P; Cartaud J
Asymmetric distribution of dystrophin in developing and adult Torpedo marmorata electrocyte: evidence for its association with the acetylcholine receptor-rich membrane.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3938-41.
1990: Jasmin B J; Changeux J P; Cartaud J
Compartmentalization of cold-stable and acetylated microtubules in the subsynaptic domain of chick skeletal muscle fibre.
Nature 1990;344(6267):673-5.
1990: Garcia L; Pinçon-Raymond M; Romey G; Changeux J P; Lazdunski M; Rieger F
Induction of normal ultrastructure by CGRP treatment in dysgenic myotubes.
FEBS letters 1990;263(1):147-52.
1990: Bessereau J L; Fontaine B; Changeux J P
Denervation of mouse skeletal muscle differentially affects the expression of the jun and fos proto-oncogenes.
The New biologist 1990;2(4):375-83.
1990: Duclert A; Piette J; Changeux J P
Induction of acetylcholine receptor alpha-subunit gene expression in chicken myotubes by blocking electrical activity requires ongoing protein synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1391-5.
1990: Mulle C; Changeux J P
A novel type of nicotinic receptor in the rat central nervous system characterized by patch-clamp techniques.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(1):169-75.
1990: Changeux J P; Benoît P; Bessis A; Cartaud J; Devillers-Thiéry A; Fontaine B; Galzi J L; Klarsfeld A; Laufer R; Mulle C
Regulation of acetylcholine receptor gene expression by neural factors and electrical activity during motor endplate formation.
Biochemical Society symposium 1990;56():9-12.
1990: Changeux J P; Babinet C; Bessereau J L; Bessis A; Cartaud A; Cartaud J; Daubas P; Devillers-Thiéry A; Duclert A; Hill J A
Compartmentalization of acetylcholine receptor gene expression during development of the neuromuscular junction.
Cold Spring Harbor symposia on quantitative biology 1990;55():381-96.
1990: Changeux J P; Benoit P; Bessis A; Cartaud J; Devillers-Thiery A; Fontaine B; Galzi J L; Klarsfeld A; Laufer R; Mulle C
The acetylcholine receptor: functional architecture and regulation.
Advances in second messenger and phosphoprotein research 1990;24():15-9.
1989: Canlon B; Cartaud J; Changeux J P
Localization of alpha-bungarotoxin binding sites on outer hair cells from the guinea-pig cochlea.
Acta physiologica Scandinavica 1989;137(4):549-50.
1989: Changeux J P; Dehaene S
Neuronal models of cognitive functions.
Cognition 1989;33(1-2):63-109.
1989: Jasmin B J; Cartaud J; Bornens M; Changeux J P
Golgi apparatus in chick skeletal muscle: changes in its distribution during end plate development and after denervation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):7218-22.
1989: Giraudat J; Gali J; Revah F; Changeux J; Haumont P; Lederer F
The noncompetitive blocker [(3)H]chlorpromazine labels segment M2 but not segment M1 of the nicotinic acetylcholine receptor alpha-subunit.
FEBS letters 1989;253(1-2):190-8.
1989: Fontaine B; Changeux J P
Localization of nicotinic acetylcholine receptor alpha-subunit transcripts during myogenesis and motor endplate development in the chick.
The Journal of cell biology 1989;108(3):1025-37.
1989: Piette J; Klarsfeld A; Changeux J P
Interaction of nuclear factors with the upstream region of the alpha-subunit gene of chicken muscle acetylcholine receptor: variations with muscle differentiation and denervation.
The EMBO journal 1989;8(3):687-94.
1989: Klarsfeld A; Laufer R; Fontaine B; Devillers-Thiéry A; Dubreuil C; Changeux J P
Regulation of muscle AChR alpha subunit gene expression by electrical activity: involvement of protein kinase C and Ca2+.
Neuron 1989;2(3):1229-36.
1989: Laufer R; Changeux J P
Calcitonin gene-related peptide and cyclic AMP stimulate phosphoinositide turnover in skeletal muscle cells. Interaction between two second messenger systems.
The Journal of biological chemistry 1989;264(5):2683-9.
1989: Changeux J P
The acetylcholine receptor: its molecular biology and biotechnological prospects.
BioEssays : news and reviews in molecular, cellular and developmental biology 1989;10(2-3):48-54.
1989: Kordeli E; Cartaud J; Nghiêm H O; Devillers-Thiéry A; Changeux J P
Asynchronous assembly of the acetylcholine receptor and of the 43-kD nu1 protein in the postsynaptic membrane of developing Torpedo marmorata electrocyte.
The Journal of cell biology 1989;108(1):127-39.
1989: Vidal C; Changeux J P
Pharmacological profile of nicotinic acetylcholine receptors in the rat prefrontal cortex: an electrophysiological study in a slice preparation.
Neuroscience 1989;29(2):261-70.
1989: Changeux J P; Fontaine B; Klarsfeld A; Laufer R; Cartaud J
Molecular biology of acetylcholine receptor long-term evolution during motor end-plate morphogenesis.
Progress in brain research 1989;79():15-25.
1989: Laufer R; Changeux J P
Activity-dependent regulation of gene expression in muscle and neuronal cells.
Molecular neurobiology 1989;3(1-2):1-53.
1989: Kirilovsky J; Duclert A; Fontaine B; Devillers-Thiery A; Osterlund M; Changeux J P
Acetylcholine receptor expression in primary cultures of embryonic chick myotubes--II. Comparison between the effects of spinal cord cells and calcitonin gene-related peptide.
Neuroscience 1989;32(2):289-96.
1989: Osterlund M; Fontaine B; Devillers-Thiery A; Geoffroy B; Changeux J P
Acetylcholine receptor expression in primary cultures of embryonic chick myotubes--I. Discoordinate regulation of alpha-, gamma- and delta-subunit gene expression by calcitonin gene-related peptide and by muscle electrical activity.
Neuroscience 1989;32(2):279-87.
1989: Fontaine B; Klarsfeld A; Laufer R; Hökfelt T; Changeux J P
[Possible trophic role on the neuromuscular junction of a neuropeptide co-existing with acetylcholine in motor neurons of the spinal cord]
Revue neurologique 1989;145(3):194-200.
1988: Mulle C; Benoit P; Pinset C; Roa M; Changeux J P
Calcitonin gene-related peptide enhances the rate of desensitization of the nicotinic acetylcholine receptor in cultured mouse muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5728-32.
1988: Dennis M; Giraudat J; Kotzyba-Hibert F; Goeldner M; Hirth C; Chang J Y; Lazure C; Chrétien M; Changeux J P
Amino acids of the Torpedo marmorata acetylcholine receptor alpha subunit labeled by a photoaffinity ligand for the acetylcholine binding site.
Biochemistry 1988;27(7):2346-57.
1988: Langenbuch-Cachat J; Bon C; Mulle C; Goeldner M; Hirth C; Changeux J P
Photoaffinity labeling of the acetylcholine binding sites on the nicotinic receptor by an aryldiazonium derivative.
Biochemistry 1988;27(7):2337-45.
1988: Fontaine B; Sassoon D; Buckingham M; Changeux J P
Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.
The EMBO journal 1988;7(3):603-9.
1988: Villar M J; Huchet M; Hökfelt T; Changeux J P; Fahrenkrug J; Brown J C
Existence and coexistence of calcitonin gene-related peptide, vasoactive intestinal polypeptide- and somatostatin-like immunoreactivities in spinal cord motoneurons of developing embryos and post-hatch chicks.
Neuroscience letters 1988;86(1):114-8.
1987: Taguchi T; Huchet M; Roa M; Changeux J P; Henderson C E
A subpopulation of embryonic telencephalic neurons survive and develop in vitro in response to factors derived from the periphery.
Brain research 1987;465(1-2):125-32.
1987: Fontaine B; Klarsfeld A; Changeux J P
Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways.
The Journal of cell biology 1987;105(3):1337-42.
1987: Henderson C E; Hauser S L; Huchet M; Dessi F; Hentati F; Taguchi T; Changeux J P; Fardeau M
Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons.
Neurology 1987;37(8):1361-4.
1987: Giraudat J; Dennis M; Heidmann T; Haumont P Y; Lederer F; Changeux J P
Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the beta and delta chains.
Biochemistry 1987;26(9):2410-8.
1987: Dehaene S; Changeux J P; Nadal J P
Neural networks that learn temporal sequences by selection.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2727-31.
1987: Revah F; Mulle C; Pinset C; Audhya T; Goldstein G; Changeux J P
Calcium-dependent effect of the thymic polypeptide thymopoietin on the desensitization of the nicotinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3477-81.
1987: Laufer R; Changeux J P
Calcitonin gene-related peptide elevates cyclic AMP levels in chick skeletal muscle: possible neurotrophic role for a coexisting neuronal messenger.
The EMBO journal 1987;6(4):901-6.
1987: Klarsfeld A; Daubas P; Bourachot B; Changeux J P
A 5'-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells.
Molecular and cellular biology 1987;7(2):951-5.
1987: Kordeli E; Cartaud J; Nghiêm H O; Changeux J P
The Torpedo electrocyte: a model system for the study of receptor-cytoskeleton interactions.
Journal of receptor research 1987;7(1-4):71-88.
1987: Kordeli E; Cartaud J; Nghiêm H O; Changeux J P
In situ localization of soluble and filamentous actin in Torpedo marmorata electrocyte.
Biology of the cell / under the auspices of the European Cell Biology Organization 1987;59(1):61-8.
1986: Hauser S L; Cazenave P A; Lyon-Caen O; Taguchi T; Huchet M; Nuret H; Changeux J P; Henderson C E
Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases.
Neurology 1986;36(12):1614-8.
1986: Heidmann O; Buonanno A; Geoffroy B; Robert B; Guénet J L; Merlie J P; Changeux J P
Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse.
Science (New York, N.Y.) 1986;234(4778):866-8.
1986: Heidmann T; Changeux J P
Characterization of the transient agonist-triggered state of the acetylcholine receptor rapidly labeled by the noncompetitive blocker [3H]chlorpromazine: additional evidence for the open channel conformation.
Biochemistry 1986;25(20):6109-13.
1986: Fontaine B; Klarsfeld A; Hökfelt T; Changeux J P
Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes.
Neuroscience letters 1986;71(1):59-65.
1986: Changeux J P; Pinset C; Ribera A B
Effects of chlorpromazine and phencyclidine on mouse C2 acetylcholine receptor kinetics.
The Journal of physiology 1986;378():497-513.
1986: Giraudat J; Dennis M; Heidmann T; Chang J Y; Changeux J P
Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2719-23.
1986: Toulouse G; Dehaene S; Changeux J P
Spin glass model of learning by selection.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(6):1695-8.
1986: Kordeli E; Cartaud J; Nghiêm H O; Pradel L A; Dubreuil C; Paulin D; Changeux J P
Evidence for a polarity in the distribution of proteins from the cytoskeleton in Torpedo marmorata electrocytes.
The Journal of cell biology 1986;102(3):748-61.
1986: Henderson C E; Benoit P; Huchet M; Guenet J L; Changeux J P
Increase of neurite-promoting activity for spinal neurons in muscles of 'paralysé' mice and tenotomised rats.
Brain research 1986;390(1):65-70.
1986: Bourgeois J P; Toutant M; Gouzé J L; Changeux J P
Effect of activity on the selective stabilization of the motor innervation of fast muscle posterior latissimus dorsi from chick embryo.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1986;4(5):415-29.
1986: Yeramian E; Changeux J P
[A model for long-term changes in synaptic efficacy based on the interaction of the acetylcholine receptor with the 43,000 dalton sub-synaptic protein]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1986;302(17):609-16.
1986: Changeux J P
Coexistence of neuronal messengers and molecular selection.
Progress in brain research 1986;68():373-403.
1985: Chemouilli P; Heidmann T; Changeux J P; Bachy A; Morre M
Allosteric effects of diprobutine on acetylcholine receptors.
European journal of pharmacology 1985;117(2):205-14.
1985: Klarsfeld A; Changeux J P
Activity regulates the levels of acetylcholine receptor alpha-subunit mRNA in cultured chicken myotubes.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(13):4558-62.
1985: Giraudat J; Montecucco C; Bisson R; Changeux J P
Transmembrane topology of acetylcholine receptor subunits probed with photoreactive phospholipids.
Biochemistry 1985;24(13):3121-7.
1984: Giraudat J; Devillers-Thiery A; Perriard J C; Changeux J P
Complete nucleotide sequence of Torpedo marmorata mRNA coding for the 43,000-dalton nu 2 protein: muscle-specific creatine kinase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7313-7.
1984: Popot J L; Changeux J P
Nicotinic receptor of acetylcholine: structure of an oligomeric integral membrane protein.
Physiological reviews 1984;64(4):1162-239.
1984: Changeux J P; Devillers-Thiéry A; Chemouilli P
Acetylcholine receptor: an allosteric protein.
Science (New York, N.Y.) 1984;225(4668):1335-45.
1984: Tzartos S J; Changeux J P
Lipid-dependent recovery of alpha-bungarotoxin and monoclonal antibody binding to the purified alpha-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers.
The Journal of biological chemistry 1984;259(18):11512-9.
1984: Henderson C E; Huchet M; Changeux J P
Neurite-promoting activities for embryonic spinal neurons and their developmental changes in the chick.
Developmental biology 1984;104(2):336-47.
1984: Bon F; Lebrun E; Gomel J; Van Rapenbusch R; Cartaud J; Popot J L; Changeux J P
Image analysis of the heavy form of the acetylcholine receptor from Torpedo marmorata.
Journal of molecular biology 1984;176(2):205-37.
1984: Benoit P; Delhaye-Bouchaud N; Changeux J P; Mariani J
Stability of multiple innervation of Purkinje cells by climbing fibers in the agranular cerebellum of old rats X-irradiated at birth.
Brain research 1984;316(2):310-3.
1984: Heidmann T; Changeux J P
Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(6):1897-901.
1984: Klarsfeld A; Devillers-Thiéry A; Giraudat J; Changeux J P
A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications.
The EMBO journal 1984;3(1):35-41.
1984: Devillers-Thiery A; Giraudat J; Bentaboulet M; Klarsfeld A; Changeux J P
Molecular genetics of Torpedo marmorata acetylcholine receptor.
Advances in experimental medicine and biology 1984;181():17-29.
1984: Cartaud J; Kordeli C; Nghiêm H O; Changeux J P
The postsynaptic domain in Torpedo marmorata electric organ: molecular architecture and stabilization mechanisms.
Progress in clinical and biological research 1984;164():255-63.
1984: Nghiêm H O; Cartaud J; Dubreuil C; Kordeli C; Petit-Koskas E; Buttin G; Changeux J P
Monoclonal antibody directed against the 43 000 dalton v1 polypeptide from Torpedo marmorata electric organ.
Developments in biological standardization 1984;57():393-8.
1984: Heidmann A; Heidmann T; Changeux J P
[Selective stabilization of neuronal representations by resonance between spontaneous prerepresentations of the cerebral network and percepts evoked by interaction with the outside world]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1984;299(20):839-44.
1983: Heidmann T; Bernhardt J; Neumann E; Changeux J P
Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata.
Biochemistry 1983;22(23):5452-9.
1983: Nghiêm H O; Cartaud J; Dubreuil C; Kordeli C; Buttin G; Changeux J P
Production and characterization of a monoclonal antibody directed against the 43,000-dalton v1 polypeptide from Torpedo marmorata electric organ.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(20):6403-7.
1983: Oswald R E; Heidmann T; Changeux J P
Multiple affinity states for noncompetitive blockers revealed by [3H]phencyclidine binding to acetylcholine receptor rich membrane fragments from Torpedo marmorata.
Biochemistry 1983;22(13):3128-36.
1983: Heidmann T; Oswald R E; Changeux J P
Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from torpedo marmorata.
Biochemistry 1983;22(13):3112-27.
1983: Henderson C E; Huchet M; Changeux J P
Denervation increases a neurite-promoting activity in extracts of skeletal muscle.
Nature 1983;302(5909):609-11.
1983: Devillers-Thiery A; Giraudat J; Bentaboulet M; Changeux J P
Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(7):2067-71.
1983: Tzartos S J; Changeux J P
High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.
The EMBO journal 1983;2(3):381-7.
1983: Gouzé J L; Lasry J M; Changeux J P
Selective stabilization of muscle innervation during development: a mathematical model.
Biological cybernetics 1983;46(3):207-15.
1983: Changeux J P
Concluding remarks: on the "singularity" of nerve cells and its ontogenesis.
Progress in brain research 1983;58():465-78.
1983: Changeux J P; Bon F; Cartaud J; Devillers-Thiéry A; Giraudat J; Heidmann T; Holton B; Nghiêm H O; Popot J L; Van Rapenbusch R
Allosteric properties of the acetylcholine receptor protein from Torpedo marmorata.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 1():35-52.
1982: Heidmann T; Changeux J P
[Molecular model of the regulation of chemical synapse efficiency at the postsynaptic level]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1982;295(12):665-70.
1982: Heidmann T; Oswald R; Changeux J P
[The high affinity binding site for chlorpromazine is present only as a single copy per cholinergic receptor molecule and is shared by four polypeptide chains]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1982;295(5):345-9.
1982: Bon F; Lebrun E; Gomel J; van Rapenbusch R; Cartaud J; Popot J L; Changeux J P
[Relative orientation of the two oligomers composing the heavy form of the acetylcholine receptor from Torpedo marmorata]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1982;295(3):199-204.
1982: Oswald R E; Changeux J P
Crosslinking of alpha-bungarotoxin to the acetylcholine receptor from Torpedo marmorata by ultraviolet light irradiation.
FEBS letters 1982;139(2):225-9.
1982: Changeux J P; Dennis S G
Signal transduction across cellular membranes.
Neurosciences Research Program bulletin 1982;20(3):267-426.
1982: Giraudat J; Devillers-Thiery A; Auffray C; Rougeon F; Changeux J P
Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.
The EMBO journal 1982;1(6):713-7.
1982: Rousselet A; Cartaud J; Devaux P F; Changeux J P
The rotational diffusion of the acetylcholine receptor in Torpeda marmorata membrane fragments studied with a spin-labelled alpha-toxin: importance of the 43 000 protein(s).
The EMBO journal 1982;1(4):439-45.
1981: Oswald R E; Changeux J P
Selective labeling of the delta subunit of the acetylcholine receptor by a covalent local anesthetic.
Biochemistry 1981;20(25):7166-74.
1981: Heidmann T; Changeux J P
Stabilization of the high affinity state of the membrane-bound acetylcholine receptor from Torpedo marmorata by noncompetitive-blockers. Evidence for dual interaction and pharmacological selectivity.
FEBS letters 1981;131(2):239-44.
1981: Cartaud J; Sobel A; Rousselet A; Devaux P F; Changeux J P
Consequences of alkaline treatment for the ultrastructure of the acetylcholine-receptor-rich membranes from Torpedo marmorata electric organ.
The Journal of cell biology 1981;90(2):418-26.
1981: Popot J L; Cartaud J; Changeux J P
Reconstitution of a functional acetylcholine receptor. Incorporation into artificial lipid vesicles and pharmacology of the agonist-controlled permeability changes.
European journal of biochemistry / FEBS 1981;118(2):203-14.
1981: Mariani J; Changeux J P
Ontogenesis of olivocerebellar relationships. II. Spontaneous activity of inferior olivary neurons and climbing fibermediated activity of cerebellar Purkinje cells in developing rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(7):703-9.
1981: Mariani J; Changeux J P
Ontogenesis of olivocerebellar relationships. I. Studies by intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the developing rat cerebellum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(7):696-702.
1981: Saitoh T; Changeux J P
Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4430-4.
1981: Oswald R; Changeux J P
Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(6):3925-9.
1981: Wennogle L P; Oswald R; Saitoh T; Changeux J P
Dissection of the 66 000-dalton subunit of the acetylcholine receptor.
Biochemistry 1981;20(9):2492-7.
1981: Henderson C E; Huchet M; Changeux J P
Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2625-9.
1981: Toutant M; Toutant J P; Renaud D; Le Douarin G; Changeux J P
[Effects of chronic medullary stimulation on the total number of sites of acetylcholinesterase activity of the posterior latissimus dorsi muscle of chick embryo]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1981;292(12):771-5.
1981: Changeux J P; Courrège P; Danchin A; Lasry J M
[A biochemical mechanism for the epigenesis of the neuromuscular junction]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1981;292(6):449-53.
1981: Heidmann T; Cuisinier J B; Changeux J P
[Preservation of the allosteric properties of the protein receptor for acetylcholine in detergent solution without addition of lipids]
Comptes rendus des séances de l'Académie des sciences. Série III, Sciences de la vie 1981;292(1):13-5.
1980: Heidmann T; Changeux J P
Interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata in the millisecond time range: resolution of an "intermediate" conformational transition and evidence for positive cooperative effects.
Biochemical and biophysical research communications 1980;97(3):889-96.
1980: Cartaud J; Popot J L; Changeux J P
Light and heavy forms of the acetylcholine receptor from Torpedo marmorata electric organ: morphological identification using reconstituted vesicles.
FEBS letters 1980;121(2):327-32.
1980: Labat-Robert J; Saitoh T; Godeau G; Robert L; Changeux J P
Distribution of macromolecules from the intercellular matrix in the electroplaque of Electrophorus electricus.
FEBS letters 1980;120(2):259-63.
1980: Heidmann T; Sobel A; Popot J L; Changeux J P
Reconstitution of a functional acetylcholine receptor. Conservation of the conformational and allosteric transitions and recovery of the permeability response; role of lipids.
European journal of biochemistry / FEBS 1980;110(1):35-55.
1980: Sobel A; Heidmann T; Cartaud J; Changeux J P
Reconstitution of a functional acetylcholine receptor. Polypeptide chains, ultrastructure, and binding sites for acetylcholine and local anesthetics.
European journal of biochemistry / FEBS 1980;110(1):13-33.
1980: Waksman G; Changeux J P; Roques B P
Structural requirements for agonist and noncompetitive blocking action of acylcholine derivatives on Electrophorus electricus electroplaque.
Molecular pharmacology 1980;18(1):20-7.
1980: Saitoh T; Oswald R; Wennogle L P; Changeux J P
Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin.
FEBS letters 1980;116(1):30-6.
1980: Mariani J; Changeux J P
[Intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the developing rat]
Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles 1980;291(1):97-100.
1980: Betz H; Bourgeois J P; Changeux J P
Evolution of cholinergic proteins in developing slow and fast skeletal muscles in chick embryo.
The Journal of physiology 1980;302():197-218.
1980: Toutant M; Bourgeois J P; Toutant J P; Renaud D; Le Douarin G; Changeux J P
Chronic stimulation of the spinal cord in developing chick embryo causes the differentiation of multiple clusters of acetylcholine receptor in the posterior latissimus dorsi muscle.
Developmental biology 1980;76(2):384-95.
1980: Wennogle L P; Changeux J P
Transmembrane orientation of proteins present in acetylcholine receptor-rich membranes from Torpedo marmorata studied by selective proteolysis.
European journal of biochemistry / FEBS 1980;106(2):381-93.
1980: Heidmann T; Sobel A; Changeux J P
Conservation of the kinetic and allosteric properties of the acetylcholine receptor in its Na cholate soluble 9 S form : effect of lipids.
Biochemical and biophysical research communications 1980;93(1):127-33.
1980: Saitoh T; Changeux J P
Phosphorylation in vitro of membrane fragments from Torpedo marmorata electric organ. Effect on membrane solubilization by detergents.
European journal of biochemistry / FEBS 1980;105(1):51-62.
1980: Waksman G; Oswald R; Changeux J P; Roques B P
Synthesis and pharmacological activity on Electrophorus electricus electroplaque of photoaffinity labelling derivatives of the non-competitive blockers di- and tri-methisoquin.
FEBS letters 1980;111(1):23-8.
1980: Oswald R; Sobel A; Waksman G; Roques B; Changeux J P
Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata.
FEBS letters 1980;111(1):29-34.
1980: Mariani J; Changeux J P
Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse.
Journal of neurobiology 1980;11(1):41-50.
1979: Saitoh T; Wennogle L P; Changeux J P
Factors regulating the susceptibility of the acetylcholine receptor protein to heat inactivation.
FEBS letters 1979;108(2):489-94.
1979: Woodhams P; Mallet J; Changeux J P; Balázs R
Immunological studies on the Purkinje cells from rat and mouse cerebella. II. Immunohistochemical specificity of the antiserum to purkinje cells.
Developmental biology 1979;72(2):320-6.
1979: Mallet J; Christen R; Changeux J P
Immunological studies on the Purkinje cells from rat and mouse cerebella. I. Evidence for antibodies characteristic of the Purkinje cells.
Developmental biology 1979;72(2):308-19.
1979: Bon C; Changeux J P; Jeng T W; Fraenkel-Conrat H
Postsynaptic effects of crotoxin and of its isolated subunits.
European journal of biochemistry / FEBS 1979;99(3):471-81.
1979: Changeux J P; Heidmann T; Popot J L; Sobel A
Reconstitution of a functional acetylcholine regulator under defined conditions.
FEBS letters 1979;105(1):181-7.
1979: Devillers-Thiery A; Changeux J P; Paroutaud P; Strosberg A D
The amino-terminal sequence of the 40,000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata.
FEBS letters 1979;104(1):99-105.
1979: Betz H; Changeux J P
Regulation of muscle acetylcholine receptor synthesis in vitro by cyclic nucleotide derivatives.
Nature 1979;278(5706):749-52.
1979: Heidmann T; Changeux J P
Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites.
European journal of biochemistry / FEBS 1979;94(1):281-96.
1979: Heidmann T; Changeux J P
Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata.
European journal of biochemistry / FEBS 1979;94(1):255-79.
1979: Changeux J P
The acetylcholine receptor: an "allosteric" membrane protein.
Harvey lectures 1979;75():85-254.
1979: Sobel A; Hofler J; Heidmann T; Changeux J P
Structural and functional properties of the acetylcholine regulator.
Advances in cytopharmacology 1979;3():191-6.
1979: Mikoshiba K; Huchet M; Changeux J P
Biochemical and immunological studies on the P400 protein, a protein characteristic of the Purkinje cell from mouse and rat cerebellum.
Developmental neuroscience 1979;2(6):254-75.
1978: Bourgeois J P; Popot J L; Ryter A; Changeux J P
Quantitative studies on the localization of the cholinergic receptor protein in the normal and denervated electroplaque from Electrophorus electricus.
The Journal of cell biology 1978;79(1):200-16.
1978: Heidmann T; Sobel A; Changeux J P
Recovery of allosteric interactions between a fluorescent cholinergic agonist and local anesthetics after removal of the detergent from cholate-solubilized membrane fragments rich in acetylcholine receptor.
FEBS letters 1978;94(2):397-404.
1978: Benoit P; Changeux J P
Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat.
Brain research 1978;149(1):89-96.
1978: Popot J L; Demel R A; Sobel A; Van Deenen L L; Changeux J P
Interaction of the acetylcholine (nicotinic) receptor protein from Torpedo marmorata electric organ with monolayers of pure lipids.
European journal of biochemistry / FEBS 1978;85(1):27-42.
1978: Merlie J P; Changeux J P; Gros F
Skeletal muscle acetylcholine receptor. Purification, characterization, and turnover in muscle cell cultures.
The Journal of biological chemistry 1978;253(8):2882-91.
1978: Mikoshiba K; Changeux J P
Morphological and biochemical studies on isolated molecular and granular layers from bovine cerebellum.
Brain research 1978;142(3):487-504.
1978: Briley M S; Changeux J P
Recovery of some functional properties of the detergent-extracted cholinergic receptor protein from Torpedo marmorata after reintegration into a membrane environment.
European journal of biochemistry / FEBS 1978;84(2):429-39.
1978: Sobel A; Heidmann T; Hofler J; Changeux J P
Distinct protein components from Torpedo marmorata membranes carry the acetylcholine receptor site and the binding site for local anesthetics and histrionicotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(1):510-4.
1978: Changeux J P; Mikoshiba K
Genetic and 'epigenetic' factors regulating synapse formation in vertebrate cerebellum and neuromuscular junction.
Progress in brain research 1978;48():43-66.
1978: Heidmann T; Changeux J P
Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states.
Annual review of biochemistry 1978;47():317-57.
1977: Sobel A; Heidmann T; Changeux J P
[Purification of a protein binding quinacrine and histrionicotoxin from membrane fragments rich in cholinergic receptors in Torpedo marmorata]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1977;285(14):1255-8.
1977: Mariani J; Crepel F; Mikoshiba K; Changeux J P; Sotelo C
Anatomical, physiological and biochemical studies of the cerebellum from Reeler mutant mouse.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1977;281(978):1-28.
1977: Grünhagen H H; Iwatsubo M; Changeux J P
Fast kinetic studies on the interaction of cholinergic agonists with the membrane-bound acetylcholine receptor from Torpedo marmorata as revealed by quinacrine fluorescence.
European journal of biochemistry / FEBS 1977;80(1):225-42.
1977: Sobel A; Weber M; Changeux J P
Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent-extracted forms from Torpedo marmorata electric organ.
European journal of biochemistry / FEBS 1977;80(1):215-24.
1977: Popot J L; Demel R A; Sobel A; van Deenen L L; Changeux J P
[Preferential affinity of acetylcholine receptor protein for certain lipids studied using monolayer cultures]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1977;285(9):1005-8.
1977: Teichberg V I; Sobel A; Changeux J P
In vitro phosphorylation of the acetylcholine receptor.
Nature 1977;267(5611):540-2.
1977: Atlas D; Teichberg V I; Changeux J P
Direct evidence for beta-adrenoreceptors on the Purkinje cells of mouse cerebellum.
Brain research 1977;128(3):532-6.
1977: Betz H; Bourgeois J P; Changeux J P
Evidnece for degradation of the acetylcholine (nicotinic) receptor in skeletal muscle during the development of the chick embryo.
FEBS letters 1977;77(2):219-24.
1977: Bon C; Changeux J P
Ceruleotoxin: a possible marker of the cholinergic ionophore.
European journal of biochemistry / FEBS 1977;74(1):43-51.
1977: Bon C; Changeux J P
Chemical and pharmacological characterization of toxic polypeptides from the venom of Bungarus caeruleus.
European journal of biochemistry / FEBS 1977;74(1):31-42.
1977: Heidmann T; Iwatsubo M; Changeux J P
[Study by a rapid mixing method of the interaction between a fluorescent cholinergic agonist and membrane fragments rich in cholinergic receptors from Torpedo marmorata]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1977;284(9):771-4.
1977: Teichberg V I; Changeux J P
Evidence for protein phosphorylation and dephosphorylation in membrane fragments isolated from the electric organ of Electrophorus electricus.
FEBS letters 1977;74(1):71-6.
1977: Sobel A; Changeux J P
Purification and characterization of the cholinergic receptor protein in its membrane-bound and detergent-soluble forms from the electric organ of Torpedo marmorata.
Biochemical Society transactions 1977;5(2):511-4.
1977: Briley M S; Changeux J P
Isolation and purification of the nicotinic acetylcholine receptor and its functional reconstitution into a membrane environment.
International review of neurobiology 1977;20():31-63.
1976: Changeux J P; Danchin A
Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks.
Nature 1976;264(5588):705-12.
1976: Merlie J P; Changeux J P; Gros F
Acetylcholine receptor degradation measured by pulse chase labelling.
Nature 1976;264(5581):74-6.
1976: Grünhagen H H; Iwatsubo M; Changeux J
[Rapid changes in the intensity of fluorescence observed in the presence of cholinergic agonists with Torpedo marmorata membrane fragments rich in cholinergic receptors and labelled with quinacrine]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1976;283(9):1105-8.
1976: Grünhagen H H; Changeux J P
Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. V. Qualitative correlation between pharmacological effects and equilibration processes of the cholinergic receptor protein as revealed by the structural probe quinacrine.
Journal of molecular biology 1976;106(3):517-35.
1976: Grünhagen H H; Changeux J P
Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. IV. Quinacrine: a fluorescent probe for the conformational transitions of the cholinergic receptor protein in its membrane-bound state.
Journal of molecular biology 1976;106(3):497-516.
1976: Sugiyama H; Popot J L; Changeux J P
Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. III. Pharmocological desensitization in vitro of the receptor-rich membrane fragments by cholinergic agonists.
Journal of molecular biology 1976;106(3):485-96.
1976: Popot J L; Sugiyama H; Changeux J P
Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. II. The permeability response of the receptor-rich membrane fragments to cholinergic agonists in vitro.
Journal of molecular biology 1976;106(3):469-83.
1976: Moreau M; Changeux J P
Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. I. Pharmacological properties of the electroplaque.
Journal of molecular biology 1976;106(3):457-67.
1976: Teichberg V I; Changeux J P
Presence of two forms of acetylcholine receptor with different isoelectric points in the electric organ of Electrophorus electricus and their catalytic interconversion in vitro.
FEBS letters 1976;67(3):264-8.
1976: Giacobini-Robecchi M G; Giacobini G; Filogamo G; Changeux J P
[Comparative action of chronic injection of alpha toxin from Naja nigricolis and of botulinum toxin A on the development of chick embryo dorsal and ventral spinal roots]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1976;283(3):271-4.
1976: Mallet J; Huchet M; Pougeois R; Changeux J P
Anatomical, physiological and biochemical studies on the cerebellum from mutant mice. III. Protein differences associated with the weaver, staggerer and nervous mutations.
Brain research 1976;103(2):291-312.
1976: Kato G; Changeux J P
Studies on the effect of histrionicotoxin on the monocellular electroplax from Electrophorus electricus and on the binding of (3H)acetylcholine to membrane fragments from Torpedo marmorata.
Molecular pharmacology 1976;12(1):92-100.
1976: Changeux J P; Benedetti L; Bourgeois J P; Brisson A; Cartaud J; Devaux P; Grünhagen H; Moreau M; Popot J L; Sobel A; Weber M
Some structural properties of the cholinergic receptor protein in its membrane environmental relevant to its function as a pharmacological receptor.
Cold Spring Harbor symposia on quantitative biology 1976;40():211-30.
1975: Benoit P; Changeux J P
Consequences of tenotomy on the evolution of multiinnervation in developing rat soleus muscle.
Brain research 1975;99(2):354-8.
1975: Bon C; Changeux J P
Ceruleotoxin: an acidic neurotoxin from the venom of Bungarus caeruleus which blocks the response to a cholinergic agonist without binding to the cholinergic receptor site.
FEBS letters 1975;59(2):212-6.
1975: Merlie J P; Sobel A; Changeux J P; Gros F
Synthesis of acetylcholine receptor during differentiation of cultured embryonic muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(10):4028-32.
1975: Grünhagen H; Changeux J P
[Structural transitions of the Torpedo cholinergic receptor in its membrane state as demonstrated by a fluorescent local anesthetic: quinacrine]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1975;281(14):1047-50.
1975: Weber M; David-Pfeuty T; Changeux J P
Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(9):3443-7.
1975: Sugiyama H; Changeux J P
Interconversion between different states of affinity for acetylcholine of the cholinergic receptor protein from Torpedo marmorata.
European journal of biochemistry / FEBS 1975;55(3):505-15.
1975: Barrantes F J; Changeux J P; Lunt G G; Sobel A
Differences between detergent-extracted acetylcholine receptor and "cholinergic proteolipid.".
Nature 1975;256(5515):325-7.
1975: Lester H A; Changeux J P; Sheridan R E
Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques.
The Journal of general physiology 1975;65(6):797-816.
1975: Brisson A; Devaux P F; Changeux J P
[Local anesthetic effect of several lipid-soluble compounds on the carbamylcholine response of the Electrophorus electroplax and the acetylcholine binding to the cholinergic receptor of Torpedo]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1975;280(18):2153-6.
1975: Mallet J; Huchet M; Pougeois R; Changeux J P
A protein difference associated with defects of the Purkinje cell in staggerer and nervous mutant mice.
FEBS letters 1975;52(2):216-20.
1975: Brisson A D; Scandella C J; Bienvenüe A; Devaux P F; Cohen J B; Changeux J P
Interaction of a spin-labeled long chain acylcholine with the cholinergic receptor protein in its membrane environment.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(3):1087-91.
1975: Cohen J B; Changeux J P
The cholinergic receptor protein in its membrane environment.
Annual review of pharmacology 1975;15():83-103.
1974: Crepel F; Mariani J; Korn H; Changeux J P
[Electrophysiology of the cerebellar cortex in the staggerer mutant mouse]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1974;277(24):2761-3.
1974: Popot J L; Sugiyama H; Changeux J P
[In vitro demonstration of drug desensitization of the acetylcholine receptor with fragments of excitable membrane from the torpedo fish]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1974;279(22):1721-4.
1974: Mallet J; Huchet M; Shelanski M; Changeux J P
Protein differences associated with the absence of granule cells in the cerebella from the mutant weaver mouse and from x-irradiated rat.
FEBS letters 1974;46(1):243-6.
1974: Sotelo C; Changeux J P
Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse.
Brain research 1974;77(3):484-91.
1974: Meunier J C; Sealock R; Olsen R; Changeux J P
Purification and properties of the cholinergic receptor protein from Electrophorus electricus electric tissue.
European journal of biochemistry / FEBS 1974;45(2):371-94.
1974: Hazelbauer G L; Changeux J P
Reconstitution of a chemically excitable membrane.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1479-83.
1974: Dupont Y; Cohen J B; Changeux J P
X-ray diffraction study of membrane fragments rich in acetylcholine receptor protein prepared from the electric organ of Torpedo marmorata.
FEBS letters 1974;40(1):130-3.
1974: Sotelo C; Changeux J P
Transsynaptic degeneration 'en cascade' in the cerebellar cortex of staggerer mutant mice.
Brain research 1974;67(3):519-26.
1974: Cohen J B; Weber M; Changeux J P
[Effect of local anesthetics on the binding properties of cholinergic receptors of the torpedo]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1974;278(9):1269-72.
1974: Weber M; Changeux J P
Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. 3. Effects of local anaesthetics on the binding of the tritiated alpha-neurotoxin.
Molecular pharmacology 1974;10(1):35-40.
1974: Weber M; Changeux J P
Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated alpha-neurotoxin.
Molecular pharmacology 1974;10(1):15-34.
1974: Weber M; Changeux J P
Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. I. Binding of the tritiated alpha-neurotoxin in the absence of effector.
Molecular pharmacology 1974;10(1):1-14.
1973: Hucho F; Changeux J P
Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue.
FEBS letters 1973;38(1):11-5.
1973: Cohen J B; Changeux J P
Interaction of a fluorescent ligand with membrane-bound cholinergic receptor from Torpedo marmorata.
Biochemistry 1973;12(24):4855-64.
1973: Bourgeois J P; Popot J L; Ryter A; Changeux J P
Consequences of denervation on the distribution of the cholinergic (nicotinic) receptor sites from Electrophorus electricus revealed by high resolution autoradiography.
Brain research 1973;62(2):557-63.
1973: Meunier J C; Sugiyama H; Cartaud J; Sealock R; Changeux J P
Functional properties of the purified cholinergic receptor protein from Electrophorus electricus.
Brain research 1973;62(2):307-15.
1973: Changeux J P; Courrège P; Danchin A
A theory of the epigenesis of neuronal networks by selective stabilization of synapses.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(10):2974-8.
1973: Sugiyama H; Benda P; Meunier J C; Changeux J P
Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus.
FEBS letters 1973;35(1):124-8.
1973: Cohen J B; Changeux J P
[Interaction of a fluorescent ligand with the protein receptor of acetylcholine present in Torpedo marmorata membrane fragments]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1973;277(6):603-6.
1973: Changeux J P
Cholinergic receptors in Electrophorus.
Neurosciences Research Program bulletin 1973;11(3):246-52.
1973: Giacobini G; Filogamo G; Weber M; Boquet P; Changeux J P
Effects of a snake alpha-neurotoxin on the development of innervated skeletal muscles in chick embryo.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(6):1708-12.
1973: Cartaud J; Benedetti E L; Cohen J B; Meunier J C; Changeux J P
Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata.
FEBS letters 1973;33(1):109-13.
1973: Meunier J C; Changeux J P
Comparison between the affinities for reversible cholinergic ligands of a purified and membrane bound state of the acetylcholine-receptor protein from Electrophorus electricus.
FEBS letters 1973;32(1):143-8.
1973: Menex A; Bouet F; Morgat J L; Ronsseray A M; Boquet P; Changeux J P; Fromageot P
Studies of tubocurarine labelled with iodine or tritium.
Biochimie 1973;55(8):919-24.
1972: Olsen R W; Meunier J C; Changeux J P
Progress in the purification of the cholinergic receptor protein from Electrophorus electricus by affinity chromatography.
FEBS letters 1972;28(1):96-100.
1972: Cohen J B; Weber M; Huchet M; Changeux J P
Purification from Torpedo marmorata electric tissue of membrane fragments particularly rich in cholinergic receptor protein.
FEBS letters 1972;26(1):43-7.
1972: Meunier J C; Olsen R W; Changeux J P
Studies on the cholinergic receptor protein from Electrophorus electricus. Effect of detergents on some hydrodynamic properties of the receptor protein in solution.
FEBS letters 1972;24(1):63-8.
1972: Lefever R; Changeux J P
[A theory for sodium ion transport during electric stimulation]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1972;275(4):591-4.
1972: Changeux J P
Studies on the molecular mechanism of the response of an excitable membrane to cholinergic agents.
Chemistry and physics of lipids 1972;8(4):355-65.
1972: Meunier J C; Olsen R W; Menez A; Fromageot P; Boquet P; Changeux J P
Some physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by a tritiated alpha-toxin from Naja nigricollis venom.
Biochemistry 1972;11(7):1200-10.
1972: Weber M; Menez A; Fromageot P; Boquet P; Changeux J P
[Effect of cholinergic agents and local anesthetics on the kinetics of binding of tritiated toxin of Naja nigricollis to the cholinergic receptor]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1972;274(10):1575-8.
1972: Changeux J P; Huchet M; Cartaud J
[Partial reconstitution of an excitable membrane after dissolution by sodium deoxycholate]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1972;274(1):122-5.
1971: Changeux J P; Meunier J C; Huchet M
Studies on the cholinergic receptor protein of Electrophorus electricus. I. An assay in vitro for the cholinergic receptor site and solubilization of the receptor protein from electric tissue.
Molecular pharmacology 1971;7(5):538-53.
1971: Meunier J C; Olsen R; Menez A; Morgat J L; Fromageot P; Ronseray A M; Boquet P; Changeux J P
[Some physical properties of the acetylcholine protein receptor studied with a radioactive neurotoxin]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1971;273(5):595-8.
1971: Meunier J C; Huchet M; Boquet P; Changeux J P
[Separation of the receptor protein of acetylcholine and acetylcholinesterase]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1971;272(1):117-20.
1970: Blumenthal R; Changeux J P
About the changes of internal ionic concentration in the isolated electroplax during chemical excitation.
Biochimica et biophysica acta 1970;219(2):398-404.
1970: Changeux J P; Kasai M; Lee C Y
Use of a snake venom toxin to characterize the cholinergic receptor protein.
Proceedings of the National Academy of Sciences of the United States of America 1970;67(3):1241-7.
1970: Changeux J P; Kasai M; Huchet M; Meunier J C
[Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1970;270(23):2864-7.
1970: Valeur B; Patrick J; Podleski T; Monnerie L; Changeux J P
[Perfecting an apparatus allowing to measure changes of extrinsic fluorescence intensit y associated with electric excitation of electroplaque isolated from gymnotus]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1970;270(21):2583-6.
1970: Kasai M; Changeux J P
[Demonstration of the excitation by cholinergic agonists from fractions of purified membranes, in vitro]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1970;270(10):1400-3.
1970: Benda P; Tsuji S; Daussant J; Changeux J P
Localization of acetylcholinesterase by immunofluorescence in eel electroplax.
Nature 1970;225(5238):1149-50.
1970: Blumenthal R; Changeux J P; Lefever R
[A theory of electric excitation of biological membranes]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1970;270(2):389-92.
1970: Podleski T; Changeux J P; Blumenthal R; Kasai M
Conformational transitions in the course of membrane excitation. In: Molecular properties of drug receptors.
Ciba Foundation symposium 1970;():197-228.
1969: Changeux J P; Gautron J; Israël M; Podleski T
[Separation of excitable membranes from the electric organ of Electrophorus electricus]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1969;269(18):1788-91.
1969: Kasai M; Changeux J P; Monnerie L
In vitro interaction of 1-anilino 8 naphthalene sulfonate with excitable membranes isolated from the electric organ of Electrophorus electricus.
Biochemical and biophysical research communications 1969;36(3):420-7.
1969: Podleski T; Meunier J C; Changeux J P
Compared effects of dithiotreitol on the interaction of an affinity-labeling reagent with acetylcholinesterase and the excitable membrane of the electroplax.
Proceedings of the National Academy of Sciences of the United States of America 1969;63(4):1239-46.
1969: Changeux J P; Ryter A; Leuzinger W; Barrand P; Podleski T
On the association of tyrocidine with acetylcholinesterase.
Proceedings of the National Academy of Sciences of the United States of America 1969;62(3):986-93.
1969: Podleski T; Changeux J P
Effects associated with permeability changes caused by gramicidin A in electroplax membrane.
Nature 1969;221(5180):541-5.
1968: Changeux J P; Podleski T R
On the excitability and cooperativity of the electroplax membrane.
Proceedings of the National Academy of Sciences of the United States of America 1968;59(3):944-50.
1968: Changeux J P; Rubin M M
Allosteric interactions in aspartate transcarbamylase. 3. Interpretation of experimental data in terms of the model of Monod, Wyman, and Changeux.
Biochemistry 1968;7(2):553-61.
1968: Changeux J P; Gerhart J C; Schachman H K
Allosteric interactions in aspartate transcarbamylase. I. Binding of specific ligands to the native enzyme and its isolated subunits.
Biochemistry 1968;7(2):531-8.
1967: Changeux J P; Thiéry J
On the mode of action of colicins: a model of regulation at the membrane level.
Journal of theoretical biology 1967;17(2):315-8.
1967: Changeux J P; Podleski T R; Wofsy L
Affinity labeling of the acetylcholine-receptor.
Proceedings of the National Academy of Sciences of the United States of America 1967;58(5):2063-70.
1967: Podleski T; Changeux J P
Electrical phenomena associated with the activity of the membrane-bound acetylcholinesterase.
Science (New York, N.Y.) 1967;157(796):1579-81.
1967: Orth G; Vielle F; Changeux J P
On the arginase of the Shope papillomas.
Virology 1967;31(4):729-32.
1966: Rubin M M; Changeux J P
On the nature of allosteric transitions: implications of non-exclusive ligand binding.
Journal of molecular biology 1966;21(2):265-74.
1966: Changeux J P
Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs.
Molecular pharmacology 1966;2(5):369-92.
1966: Changeux J P
[Effects of ionic forces and curarizing agents on the acetylcholine esterase properties of the electric tissue of Torpedo marmorata]
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1966;262(8):937-40.
1966: Sanchez C; Changeux J P
[On the properties of biosynthetic L-threonine desaminase of a mutant of E. coli K 12]
Bulletin de la Société de chimie biologique 1966;48(5):705-13.
1965: MONOD J; WYMAN J; CHANGEUX J P
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.
Journal of molecular biology 1965;12():88-118.
1965: CHANGEUX J P
THE CONTROL OF BIOCHEMICAL REACTIONS.
Scientific American 1965;212():36-45.
1965: CHANGEUX J P
[ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHESIZED L-THREONINE DEAMINASE. VI. GENERAL DISCUSSION.]
Bulletin de la Société de chimie biologique 1965;47():281-300.
1965: CHANGEUX J P
[ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHESIZED L-THREONINE DEAMINASE. V. THE ALLOSTERIC TRANSITION.]
Bulletin de la Société de chimie biologique 1965;47():267-80.
1965: CHANGEUX J P
[ON THE ALLOSTERIC OF BIOSYNTHESIZED L-THREONINE DEAMINASE. IV. THE DESENSITIZATION PHENOMENON.]
Bulletin de la Société de chimie biologique 1965;47():113-39.
1964: CHANGEUX J P
ALLOSTERIC INTERACTIONS INTERPRETED IN TERMS OF QUATERNARY STRUCTURE.
Brookhaven symposia in biology 1964;17():232-49.
1964: CHANGEUX J P
[ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHETIC L-THREONINE DEAMINASE. II. KINETICS OF ACTION OF BIOSYNTHETIC L-THREONINE DEAMINASE WITH RESPECT TO THE NATURAL SUBSTRATE AND INHIBITOR.]
Bulletin de la Société de chimie biologique 1964;46():947-61.
1964: CHANGEUX J P
[ON THE ALLOSTERIC PROPERTIES OF L-THREONINE DEAMINASE. I. METHODS OF STUDYING BIOSYNTHETIC L-THREONINE DEAMINASE.]
Bulletin de la Société de chimie biologique 1964;46():927-46.
1964: CHANGEUX J P
[ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHETIC L-THREONINE DEAMINASE. 3. INTERPRETATION OF THE INHIBITORY EFFECT OF L-ISOLEUCINE: STERIC HINDRANCE OR ALLOSTERIC EFFECT.]
Bulletin de la Société de chimie biologique 1964;46():1151-73.
1963: MONOD J; CHANGEUX J P; JACOB F
Allosteric proteins and cellular control systems.
Journal of molecular biology 1963;6():306-29.
1962: CHANGEUX J P
[Effect of L-threonine and L-isoleucine analogs on L-threonine desaminase.]
Journal of molecular biology 1962;4():220-5.
1961: CHANGEUX J P
The feedback control mechanisms of biosynthetic L-threonine deaminase by L-isoleucine.
Cold Spring Harbor symposia on quantitative biology 1961;26():313-8.
1960: CHANGEUX J P
[On the biochemical expression of genetic determinants of Escherichia coli introduced to Salmonella typhimurium.]
Comptes rendus hebdomadaires des séances de l'Académie des sciences 1960;250():1575-7.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Jean-Pierre Changeux

Research Profile (preview)

Chemicals & Drugs

Physiology

Living Beings

Anatomy

Concepts & Ideas

Genes & Molecular Sequences

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Jean-Pierre Changeux (preview)

All Publications